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Miyoshi Hiroyuki  三好 浩之

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MIYOSHI Hiroyuki  三好 浩之

三好 浩之  ミヨシ

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Researcher Number 70219830
External Links
Affiliation (based on the past Project Information) *help 2016 – 2018: 慶應義塾大学, 医学部(信濃町), 特任准教授
2015: 慶應義塾大学, 医学部, 特任准教授
2007: RIKEN Bio Resource Center, Subteam for Manipulation of Cell Fate, Team leader
2006: 独立行政法人理化学研究所, 生体情統合技術開発チーム, チームリーダー
2003 – 2005: 独立行政法人理化学研究所, 生体情報統合技術開発チーム, サブチームリーダー
1990: 埼玉県立がんセンター, 研究所血清ウィルス部, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Genome biology / Applied genomics / Biological Sciences
Except Principal Investigator
Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
siRNA / 遺伝子治療 / ゲノム編集 / 神経幹細胞 / iPS細胞 / 自殺遺伝子治療 / 悪性グリオーマ / エピゲノム / リプログラミング / 細胞老化 … More / gene function analysis / gene transfer / vector / lentivirus / 遺伝子機能解析 / 遺伝子導入 / ベクター / レンチウイルス / 幹細胞 / 再プログラム化 / クローン / 核移植 … More
Except Principal Investigator
gene therapy / virus vector / enkephalin / severe pain / 疼痛 / ペインクリニック / ウイルスベクター / 遺伝子治療 / ウイノレスべクター / エンケフアリン / 難治性疼痛 / NotIリンキングクロ-ン / NotI制限酵素地図 / ヒト21番染色体 / 家族性アルツハイマ-病 Less
  • Research Projects

    (6 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (10 People)
  •  ゲノム編集による自殺遺伝子導入iPS細胞を用いた悪性グリオーマの遺伝子細胞治療Principal Investigator

    • Principal Investigator
      三好 浩之
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Keio University
  •  Epigenetic analysis of cellular senescence using the technology for reprogramming cellsPrincipal Investigator

    • Principal Investigator
      Miyoshi Hiroyuki
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Genome biology
    • Research Institution
      Keio University
  •  Basic study of gene therapy for severe pain by using virus vector

    • Principal Investigator
      INOMATA Shinichi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Tsukuba
  •  組織幹細胞を用いた核移殖クローンマウスの作成と再プログラム化の解析Principal Investigator

    • Principal Investigator
      三好 浩之
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Development of method for gene function analysis using lentiviral vectorsPrincipal Investigator

    • Principal Investigator
      MIYOSHI Hiroyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied genomics
    • Research Institution
      RIKEN
  •  ヒト21番染色体DNAの制限酵素地図の作成

    • Principal Investigator
      大木 操
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center

All 2019 2018 2017 2004

All Journal Article Presentation Book

  • [Book] バイオロジクスの開発と品質・安全性確保 下巻 第4部 第2章 第4節 レンチウイルスベクター2018

    • Author(s)
      三好浩之
    • Total Pages
      504
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-18K07301
  • [Book] バイオロジクスの開発と品質・安全性確保 下巻 第4部 第2章 第4節 レンチウイルスベクター2018

    • Author(s)
      三好浩之
    • Total Pages
      504
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-15K06900
  • [Journal Article] Increased Cytotoxicity of Herpes Simplex Virus Thymidine Kinase Expression in Human Induced Pluripotent Stem Cells2019

    • Author(s)
      Iwasawa Chizuru、Tamura Ryota、Sugiura Yuki、Suzuki Sadafumi、Kuzumaki Naoko、Narita Minoru、Suematsu Makoto、Nakamura Masaya、Yoshida Kazunari、Toda Masahiro、Okano Hideyuki、Miyoshi Hiroyuki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 4 Pages: 810-810

    • DOI

      10.3390/ijms20040810

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07301, KAKENHI-PROJECT-18K19622, KAKENHI-PROJECT-15K06900
  • [Journal Article] Tbx6 Induces Nascent Mesoderm from Pluripotent Stem Cells and Temporally Controls Cardiac versus Somite Lineage Diversification.2018

    • Author(s)
      Sadahiro T, Isomi M, Muraoka N, Kojima H, Haginiwa S, Kurotsu S, Tamura F, Tani H, Tohyama S, Fujita J, Miyoshi H, Kawamura Y, Goshima N, Iwasaki YW, Murano K, Saito K, Oda M, Andersen P, Kwon C, Uosaki H, Nishizono H, Fukuda K, Ieda M
    • Journal Title

      Cell stem cell

      Volume: 23(3) Issue: 3 Pages: 382-395

    • DOI

      10.1016/j.stem.2018.07.001

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08644, KAKENHI-PROJECT-18K07301, KAKENHI-PROJECT-18K08085, KAKENHI-PROJECT-18K08114, KAKENHI-PROJECT-17K19678, KAKENHI-PROJECT-17K16024, KAKENHI-PUBLICLY-17H05603, KAKENHI-PROJECT-18H02421, KAKENHI-PROJECT-17J06637, KAKENHI-PROJECT-18J21479, KAKENHI-PROJECT-16K19426
  • [Journal Article] Enhancing T cell Receptor Stability in Rejuvenated iPSC-derived T cells improves their use in cancer immunotherapy2018

    • Author(s)
      Minagawa A, Yoshikawa T, Yasukawa M, Hotta A, Kunitomo M, Iriguchi S, Takiguchi M, Kassai Y, Imai E, Yasui Y, Kawai Y, Zhang R, Uemura Y, Miyoshi H, Nakanishi M, Watanabe A, Hayashi A, Kawana K, Fujii T, Nakatsura T, Kaneko S
    • Journal Title

      Cell Stem Cell

      Volume: 23 Issue: 6 Pages: 850-858

    • DOI

      10.1016/j.stem.2018.10.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10717, KAKENHI-PROJECT-17K10806, KAKENHI-PROJECT-17KT0108, KAKENHI-PROJECT-18K07301, KAKENHI-PROJECT-18K16085, KAKENHI-PROJECT-16H05194, KAKENHI-PROJECT-15K06900, KAKENHI-PROJECT-18H02839, KAKENHI-PROJECT-18H02641, KAKENHI-PROJECT-18H02826
  • [Journal Article] Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury2018

    • Author(s)
      Kojima Kota、Miyoshi Hiroyuki、Nagoshi Narihito、Kohyama Jun、Itakura Go、Kawabata Soya、Ozaki Masahiro、Iida Tsuyoshi、Sugai Keiko、Ito Shuhei、Fukuzawa Ryuji、Yasutake Kaori、Renault-Mihara Francois、Shibata Shinsuke、Matsumoto Morio、Nakamura Masaya、Okano Hideyuki
    • Journal Title

      STEM CELLS Translational Medicine

      Volume: 8 Issue: 3 Pages: 260-270

    • DOI

      10.1002/sctm.18-0096

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07301, KAKENHI-PROJECT-15K06900, KAKENHI-PROJECT-16K21360
  • [Journal Article] Genetically Encoded Tools for Optical Dissection of the Mammalian Cell Cycle2017

    • Author(s)
      Sakaue-Sawano Asako、Yo Masahiro、Komatsu Naoki、Hiratsuka Toru、Kogure Takako、Hoshida Tetsushi、Goshima Naoki、Matsuda Michiyuki、Miyoshi Hiroyuki、Miyawaki Atsushi
    • Journal Title

      Molecular Cell

      Volume: 68 Issue: 3 Pages: 626-640

    • DOI

      10.1016/j.molcel.2017.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K06900, KAKENHI-PROJECT-16K21109, KAKENHI-PLANNED-15H05948, KAKENHI-PUBLICLY-16H01653, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Method tor gene transfer (lentiviral vector)2004

    • Author(s)
      Miyoshi, H.
    • Journal Title

      Experimental Medicine

      Pages: 147-151

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510167
  • [Journal Article] 遺伝子導入法(レンチウイルスベクター)2004

    • Author(s)
      三好浩之
    • Journal Title

      実験医学別冊 免疫学的プロトコール

      Pages: 147-151

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510167
  • [Journal Article] Gene delivery to hematopoietic stem cells using lentiviral vectors.2004

    • Author(s)
      Miyoshi, H
    • Journal Title

      Methods Mol.Biol. 246

      Pages: 429-438

    • Data Source
      KAKENHI-PROJECT-15510167
  • [Journal Article] Gene delivery to hematopoietic stem cells using lentiviral vectors.2004

    • Author(s)
      Miyoshi, H.
    • Journal Title

      Methods Mol.Biol. 246

      Pages: 429-438

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510167
  • [Journal Article] 造血幹細胞の可塑性2004

    • Author(s)
      三好浩之
    • Journal Title

      実験医学 22

      Pages: 6-11

    • Data Source
      KAKENHI-PROJECT-16045219
  • [Presentation] Reducing the risks of tumorigenesis following human induced pluripotent stem cell-derived neural stem/progenitor cell (iPS-NS/PC) transplantation in spinal cord injury - The role of suicide genes2018

    • Author(s)
      Kota Kojima, Hiroyuki Miyoshi, Narihito Nagoshi, Shuhei Ito, Go Itakura, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
    • Organizer
      5th TERMIS (Tissue Engineering and Regenerative Medicine International Society) World Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07301
  • [Presentation] ゲノム編集iPS細胞を用いた悪性神経膠腫に対する自殺遺伝子治療2018

    • Author(s)
      Ryota Tamura, Hiroyuki Miyoshi, Yutaka Mine, Yukina Morimoto, Oltea Sampetrean, Hideyuki Saya, Kazunari Yoshida, Hideyuki Okano, Masahiro Toda
    • Organizer
      第77回日本脳神経外科学会総会
    • Data Source
      KAKENHI-PROJECT-18K07301
  • [Presentation] Reducing the risk of tumorigenesis following human induced pluripotent stem cell-derived neural stem/progenitor cell (iPS-NS/PC) transplantation in spinal cord injury2018

    • Author(s)
      Kota Kojima, Hiroyuki Miyoshi, Narihito Nagoshi, Shuhei Ito, Go Itakura, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
    • Organizer
      47th Japanese Society for Spine Surgery and Related Research
    • Data Source
      KAKENHI-PROJECT-18K07301
  • [Presentation] ゲノム編集iPS細胞を用いた悪性神経膠腫に対する自殺遺伝子治療2018

    • Author(s)
      Ryota Tamura, Hiroyuki Miyoshi, Yutaka Mine, Yukina Morimoto, Oltea Sampetrean, Hideyuki Saya, Kazunari Yoshida, Hideyuki Okano, Masahiro Toda
    • Organizer
      第36回日本脳腫瘍学会
    • Data Source
      KAKENHI-PROJECT-18K07301
  • [Presentation] Selective ablation of tumorigenic cells following human iPS-NS/PC transplantation in spinal cord injury using suicide genes for improving the safety of stem cell therapy2018

    • Author(s)
      Kota Kojima, Hiroyuki Miyoshi, Narihito Nagoshi, Shuhei Ito, Go Itakura, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
    • Organizer
      57th International Spinal Cord Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07301
  • 1.  INOMATA Shinichi (10282352)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  大木 操 (00158792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  市川 仁 (30201924)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  菊地 喜美子 (00161414)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  井上 貴美子 (70360500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YOSHIDA Naomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YO Masahiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  村野 健作
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  植村 靖史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  張 エイ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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