Tanabe Osamu 田邉修

… Alternative Names

TANABE Osamu 田邉修

TANABE OSAMU 田邉修

田邊修タナベオサム

田邉修タナベオサム

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Researcher Number	70221398
Other IDs
External Links
Affiliation (Current)	2025: 公益財団法人放射線影響研究所, バイオサンプル研究センター, センター長
Affiliation (based on the past Project Information) *help	2019 – 2025: 公益財団法人放射線影響研究所, バイオサンプル研究センター, センター長 2015 – 2017: 東北大学, 東北メディカル・メガバンク機構, 教授 2014: 東北大学, 東北メディカル・メガバンク機構, 非常勤講師 1997 – 2000: 広島大学, 医学部, 講師 1995: 広島大学, 医学部, 講師 … More 1992 – 1994: Hiroshima University School of Medicine, Research Associate, 医学部, 助手 1991: 広島大学, 医学部附属病院, 助手 1990 – 1991: Medical Hospital, Hiroshima Unv., Research Associate, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related / General medical chemistry / Hematology / General medical chemistry / Pathological medical chemistry Except Principal Investigator General medical chemistry / Basic Section 63020:Radiation influence-related / Hematology / Pediatrics / Functional biochemistry / Biological Sciences / Structural biochemistry / Pathological medical chemistry
Keywords	Principal Investigator プロテインホスファターゼ2A / 体細胞変異 / 変異シグネチャー / DNA損傷 / NF-IL6 / 細胞質分裂 / 遺伝子破壊株 / 分裂酵母 / B'サブユニット / 調節サブユニット … More / 調節サブユニットδ / 老化 / クローン化 / 悪性腫瘍 / 晩発障害 / バイオドシメトリ / 全ゲノムシーケンス解析 / 骨髄性白血病 / 変異マウス / 白血病 / 胸腺リンパ腫 / Keap1 / NRF2 / 酸化ストレス応答 / 活性酸素 / 造血幹細胞 / X線 / 全ゲノムシーケンス / Transcriptional Factor / Growth Factor / Autocrine / Interleukin-6 / Multiple Myeloma / ゲル・シフト・アッセイ / RTーPCR / NFーIL6 / オ-トクライン / インタ-ロイキン6(ILー6) / 転写調節因子 / 増殖因子 / オートクライン / インターロイキン6 / 多発性骨髄腫 / グロビンスイッチング / ヘモグロビンスイッチング / エピジェネティクス / DNAメチル化 / ヒストン修飾 / 赤血球 / ノックアウトマウス / TR4 / TR2 / 核内受容体 / DNAメチル基転移酵素1 / 遺伝子発現制御 / 胎児型γグロビン / 胚型εグロビン / βグロビン異常症 / 細胞形態 / 染色体分配 / スプライスバリアント / 増殖 / δサブユニット / 核移行シグナル / cDNAクローニング / 一次構造 / cDNA … More Except Principal Investigator プロテインホスファターゼ2A / リン酸化・脱リン酸化 / 赤血球 / プロテインホスファターゼ / ヒト赤血球 / cDNAクローニング / 体細胞変異 / Myeloma cells / Autocrine growth / 骨髄腫細胞 / 転写因子 / 調節サブユニット / 脳 / 74kDa調節サブユニット / 2価金属イオン / 酵素サブユニットの再構成 / 脱リン酸化酵素 / C-キナーゼ / A-キナーゼ / タイプ2Aホスファターゼ / バイオドシメトリ / 放射線被ばく / クローン造血 / 変異シグネチャー / 放射線 / 血清バイオマーカー / 高頻度遺伝子変異 / 発症リスク / 血中バイオマーカー / SNPマイクロアレイ / 創始者変異 / 一塩基多型 / 発症リスク評価 / 頭部MRI検査 / 遺伝子多型 / RNF213遺伝子 / 遺伝子検査 / 頭部MRI / 東北メディカル・メガバンク / 頭部MRI/MRA検査 / RNF213遺伝子変異 / もやもや病 / Human erythrocytes / Inhibitor peptides / B" binding proteins / 74kDa subunit B" / Regulatory subunits / threonine protein phosphatase / Serine / Protein phosphatase 2A / Protein phosphorylation / B^<11>結合タンパク質 / 74kDaB^<11>サブユニット / トレオニンホフファターゼ / 阻害ペプチド / B"結合タンパク質 / 74kDaB"サブユニット / トレオニンホスファターゼ / セリン / タンパク質リン酸化 / Cell sorter / Monoclonal antibody / Precursor cells / Stromal cells / Integrin / Adhesion molecules / Myeloma / モノクロ-ナル抗体 / 骨髄ストロ-マ細胞 / セルソーター / モノクローナル抗体 / 前駆細胞 / 骨髄ストローマ細胞 / インテグリン / 接着分子 / 骨髄腫 / Nuclear factor / Transcriptional factor / Gene activation / Interleukin-6 / NF-IL-6 / Nuclear binding protein / Transcriptional Regulation / Interleukin 6 gene / Multiple Myeloma / オ-トクリン増殖 / 核内蛋白 / 転写調節因子 / 遺伝子発現 / ILー6 / AP-1 / 細胞死 / 癌遺伝子 / Maf / 細胞骨格 / 核構造 / クロマチン構造 / LCR / 74kDaB″ / 74kDaB" / 遺伝子破壊株 / 分裂酵母 / リン酸化 / Aキナーゼ / 解離・再構成 / 組織分布 / 核移行シグナル / 74kDaサブユニット / 蛋白質脱リン酸化 Less

放射線誘発DNA二重鎖切断のゲノムワイド・マッピングによる変異形成プロセスの解明Principal Investigator
- Principal Investigator
  
  田邉修
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Analysis of changes in radiation-induced mutational signatures induced by DNA repair inhibitors and their impact on carcinogenic risk.
- Principal Investigator
  
  松田由喜子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Time-resolved biodosimetry based on clonal hematopoiesis and somatic mutations in atomic-bomb survivors
- Principal Investigator
  
  吉田健吾
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Whole-genome sequence analysis of radiation-induced mutations in human hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  田邉修
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Study on Protective Effects of NRF2, an Anti-oxidative Stress Transcription Factor, against Radiation-induced Oncogenesis and MutagenesisPrincipal Investigator
- Principal Investigator
  
  TANABE Osamu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
RNF213 gene related intracranial findings and risk evaluation for moyamoya disease
- Principal Investigator
  
  Kure Shigeo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Role of DNA Methyltransferase 1 in the Epigenetic Regulation of Beta-type Globin GenesPrincipal Investigator
- Principal Investigator
  
  TANABE OSAMU
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
BTB型転写因子によるクロマチン構造と核内構造の共役
- Principal Investigator
  
  五十嵐和彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hiroshima University
Bachファミリーによる細胞の増殖と死の制御
- Principal Investigator
  
  五十嵐和彦
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
細胞分裂期におけるプロテインホスファターゼ2Aの機能Principal Investigator
- Principal Investigator
  
  田邉修
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hiroshima University
プロテインホスファターゼ2Aの74kDa調節サブユニットδの機能解析Principal Investigator
- Principal Investigator
  
  田邉修 (田邊修)
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
プロテインホスファターゼ2Aの活性制御に関する研究
- Principal Investigator
  
  武田誠郎
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
Development of specific inhibitor peptides against protein phosphatase 2A and its transduction into cultured cells
- Principal Investigator
  
  TAKEDA Masao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  HIROSHIMA UNIVERSITY
ヒト赤血球プロテインホスファターゼ2Aの活性制御機構の研究
- Principal Investigator
  
  武田誠郎
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
プロテインホスファターゼ2Aの74KDa調節サブユニットδの構造と機能
- Principal Investigator
  
  碓井裕史
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Hiroshima University
プロテインホスファターゼ2Aの74KD調節サブユニットδの一次構造解析Principal Investigator
- Principal Investigator
  
  田邉修
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
ヒト赤血球プロテインホスファターゼ2Aの活性制御に関する研究
- Principal Investigator
  
  武田誠郎
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
プロテインホスファターゼ2Aの74KDの調節サブユニットδのcDNAクローニングPrincipal Investigator
- Principal Investigator
  
  田邉修
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hiroshima University
タイプ2Aプロテインホスファターゼの活性制御に関する基礎的研究
- Principal Investigator
  
  TAKEDA Masao
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
ヒト赤血球タイプ2Aプロテインホスファターゼの活性調節機構の研究
- Principal Investigator
  
  碓井裕史
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hiroshima University
Growth Regulation of Human Myeloma cells: Regulatory Mechanism in the bone marrow microenvironment.
- Principal Investigator
  
  KAWANO Michio
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  HIROSHIMA UNIVERSITY
The transcriptional factor involved in the constitutive expression of interleukin-6 in multiple myelomaPrincipal Investigator
- Principal Investigator
  
  TANABE Osamu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  HIROSHIMA UNIVERSITY
Mechanism of IL-6 Gene Activation in Myeloma Cells
- Principal Investigator
  
  KAWANO Michio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Hiroshima University

All 2023 2022 2017 2015 Other

All Journal Article Presentation Other

[Journal Article] Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells2023
- Author(s)
  Matsuda Yukiko、Uchimura Arikuni、Satoh Yasunari、Kato Naohiro、Toshishige Masaaki、Kajimura Junko、Hamasaki Kanya、Yoshida Kengo、Hayashi Tomonori、Noda Asao、Tanabe Osamu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 15
- DOI
  10.1073/pnas.2216550120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K12388, KAKENHI-PROJECT-23K28234
[Journal Article] The orphan nuclear receptor TR4 regulates erythroid cell proliferation and maturation.2017
- Author(s)
  Mary P. Lee, Osamu Tanabe, Lihong Shi, Natee Jearawiriyapaisarn, Daniel Lucas, James Douglas Engel
- Journal Title
  
  Blood
  
  Volume: 130 Issue: 23 Pages: 2537-2547
- DOI
  10.1182/blood-2017-05-783159
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460355
[Journal Article] Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation.2015
- Author(s)
  Nadine Keleku-Lukwete, Mikiko Suzuki, Akihito Otsuki, Kouhei Tsuchida, Saori Katayama, Makiko Hayashi, Eriko Naganuma, Takashi Moriguchi, Osamu Tanabe, James Douglas Engel, Masue Imaizumi, Masayuki Yamamoto
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 112 Issue: 39 Pages: 12169-12174
- DOI
  10.1073/pnas.1509158112
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460355, KAKENHI-PROJECT-26461395, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-26670463
[Journal Article] Compound loss of function of nuclear receptors Tr2 and Tr4 leads to induction of murine embryonic β-type globin genes.2015
- Author(s)
  Shuaiying Cui, Osamu Tanabe, Michael Sierant, Lihong Shi, Andrew Campbell, Kim-Chew Lim, James Douglas Engel
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 9 Pages: 1477-1487
- DOI
  10.1182/blood-2014-10-605022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460355
[Presentation] 全身X線照射後のマウス造血幹細胞の体細胞変異とクローン動態の全ゲノムシーケンスによる解析2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] 原爆被爆者及び被爆二世のバイオレポジトリ2023
- Author(s)
  田邉修
- Organizer
  第63回原子爆弾後障害研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Genome-wide frequencies and signatures of somatic mutations introduced by whole-body X-irradiation in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  17th International Congress for Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] X線照射によりマウス造血幹細胞に誘発される体細胞変異とクローン性増殖2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本放射線影響学会第66会大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Longitudinal trajectories of clonal hematopoiesis before and after 3-Gy whole-body irradiation in mice2023
- Author(s)
  Yoshida K, Uchimura A, Satou Y, Matsuda Y, Tanabe O, Noda A, Misumi M, Kusunoki Y
- Organizer
  17th International Congress of Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] Genome-wide analysis of radiation-induced somatic mutations in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kume K, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  73rd Annual Meeting of the American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] 全身X線照射後のマウス造血幹細胞の体細胞変異とクローン動態の全ゲノムシーケンスによる解析2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Genome-wide analysis of radiation-induced somatic mutations in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kume K, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  75th Annual Meeting of the American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] X線照射によりマウス造血幹細胞に誘導される体細胞変異の頻度と特徴2022
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、久保美子、山岡美佳、濱崎幹也、吉田健吾、野田朝男、田邉修
- Organizer
  日本放射線影響学会第 65 回大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] X 線照射マウスの造血幹細胞における体細胞変異の頻度と特徴2022
- Author(s)
  田邉修、松田由喜子
- Organizer
  日本環境変異原ゲノム学会第51回大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] NRF2 protects sickle cell disease model mice from inflammation and organ damage.2015
- Author(s)
  Keleku-Lukwete N, 鈴木未来子, 大槻晃史, 土田恒平, 片山紗乙莉, 林真貴子, 森口尚, 田邉修, 今泉益栄, 山本雅之
- Organizer
  日本生化学会東北支部第81回例会・シンポジウム
- Place of Presentation
  東北大学片平さくらホール（宮城県・仙台市）
- Year and Date
  2015-05-09
- Data Source
  KAKENHI-PROJECT-26460355
[Presentation] Keap1-Nrf2 System: potential role in prevention of sickle cell disease organ damages and inflammation.2015
- Author(s)
  Keleku-Lukwete N, Suzuki M, Otsuki A, Tsuchida K, Katayama S, Hayashi M, Naganuma E, Moriguchi T, Tanabe O, Engel JD, Imaizumi M, Yamamoto M
- Organizer
  57th ASH Annual Meeting & Exposition
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460355
[]

1. USUI Hirofumi (40127618)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. TAKEDA Masao (40030853)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. NISHITO Yasumasa (40284187)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. 松田由喜子 (10735301)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
5. KURAMOTO Atsushi (50034070)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KAWANO Michio (40161343)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 有木政博 (50212642)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. 内村有邦 (20513063)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
9. 五十嵐和彦 (00250738)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 吉田健吾 (70443596)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
11. FUJIMURA King (80034114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Kure Shigeo (10205221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKI YASUYUKI (10375115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 鈴木未来子 (80508309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 横澤潤二 (10722605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 西川慧 (40722616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 冨永悌二 (00217548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 吉田稚明 (20832926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 楠洋一郎 (60333548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 濱崎幹也 (80443597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Tanabe Osamu 田邉 修

TANABE Osamu 田邉 修

TANABE OSAMU 田邉 修

田邊 修 タナベ オサム

田邉 修 タナベ オサム

Research Projects

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放射線誘発DNA二重鎖切断のゲノムワイド・マッピングによる変異形成プロセスの解明Principal Investigator

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Whole-genome sequence analysis of radiation-induced mutations in human hematopoietic stem cellsPrincipal Investigator

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Study on Protective Effects of NRF2, an Anti-oxidative Stress Transcription Factor, against Radiation-induced Oncogenesis and MutagenesisPrincipal Investigator

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Role of DNA Methyltransferase 1 in the Epigenetic Regulation of Beta-type Globin GenesPrincipal Investigator

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細胞分裂期におけるプロテインホスファターゼ2Aの機能Principal Investigator

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プロテインホスファターゼ2Aの74kDa調節サブユニットδの機能解析Principal Investigator

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Tanabe Osamu 田邉修

TANABE Osamu 田邉修

TANABE OSAMU 田邉修

田邊修タナベオサム

田邉修タナベオサム