Kadokura Hiroshi 門倉広

… Alternative Names

KADOKURA Hiroshi 門倉広

門倉広カドクラヒロシ

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Researcher Number	70224558
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 特任准教授
Affiliation (based on the past Project Information) *help	2024: 東京工業大学, 科学技術創成研究院, 特任准教授 2013 – 2023: 東北大学, 多元物質科学研究所, 准教授 2022: 東京工業大学, 科学技術創成研究院, 特任准教授 2012: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 博士研究員 2009 – 2012: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 研究員 … More 1999 – 2000: 東大, 農学生命科学研究科, 助手 1996 – 1998: 東京大学, 大学院・農学生命科学研究科, 助手 1991 – 1994: 東京大学, 農学部, 助手 Less
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / Basic Section 38030:Applied biochemistry-related / Applied biochemistry / 応用微生物学・発酵学 / Transformative Research Areas, Section (III) / Medium-sized Section 38:Agricultural chemistry and related fields / Applied microbiology Except Principal Investigator Biological Sciences / 応用微生物学・応用生物化学 / 応用微生物学・発酵学 / Biological Sciences
Keywords	Principal Investigator ジスルフィド結合 / 哺乳動物 / 小胞体 / 分泌タンパク質 / 物質生産 / フォールディング / PDI / 立体構造形成 / ペリプラズム / 哺乳動物細胞 … More / ストレス応答 / タンパク質分泌 / 大腸菌 / 還元力 / ジスルフィド結合形成 / 新生鎖 / マルチドメインタンパク質 / タンパク質生産 / 生合成 / 生合成阻害剤 / PD-1 / IL6R / シグナル配列 / 阻害剤 / 細胞表層タンパク質 / 低分子化合物 / 膵臓 / JPDI / 品質管理 / 動物細胞 / ジスルフィド / 微生物機能 / 外膜 / DsbA / 分泌 / プロテアーゼ / C型肝炎ウイルス … More Except Principal Investigator 枯草菌 / アルカリ性エラスターゼ / タンパク質品質管理 / Ｘ線結晶構造解析 / 高速原子間力顕微鏡 / X線結晶構造解析 / ジスルフィド結合 / petide ligase / Bacillus subtilis / thiolsubtilisin / elastase / protease / subtilisin YaB / alkalophilic Bacillus / サチライシンBPN' / チオールサチライシンYaB / ペプチドリガーゼ / チオールサチライシン / エラスターゼ / プロテアーゼ / サチライシンYaB / 好アルカリ性バチルス / protein engineering / subtilisin / meat-tenderizer / alkaline elastase / 食肉軟化 / 大腸菌 / エラスタ-ゼ / サチライシンE / 食肉軟化剤 / 蛋白質工学 / サチライシン / 食肉軟化用酵素 / HSP40 / 蛋白質品質管理 / ノックアウトマウス / 糖尿病 / 構造異常蛋白質 / 小胞体 / ストレス / Hsp40 / 転写翻訳調節 / シグナル伝達 / 小胞体ストレス Less

ヒト小胞体におけるタンパク質の正確で迅速なジスルフィド結合形成を可能にする仕組みPrincipal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Institute of Science Tokyo
  Tohoku University
翻訳途上の新生鎖に隠された新しい仕組みによって促進されるタンパク質の折り畳み機構Principal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tohoku University
Screening for small molecule compounds that inhibit the biosynthesis of a specific cell-surface proteinPrincipal Investigator
- Principal Investigator
  
  Kadokura Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Tohoku University
Mechanism of protein disulfide bond formation in the ER of human cellsPrincipal Investigator
- Principal Investigator
  
  Kadokura Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Tohoku University
Mechanisms of protein disulfide bond formation in the ER of mammalian cellsPrincipal Investigator
- Principal Investigator
  
  Kadokura Hiroshi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Tohoku University
Elucidation of mechanisms underlying disulfide bond formation in nascent chains
- Principal Investigator
  
  Kenji Inaba
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Mechanisms of protein disulfide bond formation in the ER of mammalian cellsPrincipal Investigator
- Principal Investigator
  
  KADOKURA Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Tohoku University
  Nara Institute of Science and Technology
Mechanisms of oxidative protein folding in the periplasm of E. coliPrincipal Investigator
- Principal Investigator
  
  KADOKURA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Nara Institute of Science and Technology
Analyses of the physiological roles of unfolded protein response
- Principal Investigator
  
  KOHNO Kenji
- Project Period (FY)
  2007 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
分泌蛋白質のジスルフィド結合形成に必要な大腸菌内膜蛋白質DsbBの機能解析Principal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
ジスルフィド結合形成促進酵素の大腸菌表層へのターゲティングPrincipal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
異種タンパク質の大腸菌ペリプラズムへの分泌生産にともなうストレス応答の解析Principal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
異常分泌タンパク質のペリプラズム生産に対する大腸菌のストレス応答の解析Principal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
C型肝炎ウイルスプロテアーゼの発見とその性質の解明Principal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
Production of thiolsubtilisin YaB and its application to peptide-ligation
- Principal Investigator
  
  YAMASAKI Makari
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  The University of Tokyo
好アルカリ性バチルスYa-B株プロテアーゼの活性発現に必要な因子の機能解析Principal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  The University of Tokyo
大腸菌におけるタンパク質の分泌生産と膜通過機構に関する研究Principal Investigator
- Principal Investigator
  
  門倉広
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  The University of Tokyo
Studies on protein engineering of a microbial elastase
- Principal Investigator
  
  YAMASAKI Makari
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  The University of Tokyo

[Journal Article] ルシフェラーゼの改変体を利用した小胞体機能の解析と有用化合物の探索2023
- Author(s)
  門倉　広
- Journal Title
  
  日本応用酵素協会誌 2022
  
  Volume: 57 Pages: 49-49
- Open Access
- Data Source
  KAKENHI-PROJECT-20K21262
[Journal Article] タンパク質立体構造形成の新規メカニズムを発見2022
- Author(s)
  門倉広
- Journal Title
  
  KAGAKU TO SEIBUTSU
  
  Volume: 60 Issue: 11 Pages: 557-559
- DOI
  10.1271/kagakutoseibutsu.60.557
- ISSN
  0453-073X, 1883-6852
- Year and Date
  2022-11-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H05711, KAKENHI-PROJECT-20K21262, KAKENHI-PROJECT-23K23520
[Journal Article] Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca2+-ATPase SERCA2b2021
- Author(s)
  Yuxia Zhang, Satoshi Watanabe, Akihisa Tsutsumi, Hiroshi Kadokura, Masahide Kikkawa and Kenji Inaba*
- Journal Title
  
  EMBO Journal
  
  Volume: 6 Issue: 19
- DOI
  10.15252/embj.2021108482
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15036, KAKENHI-PUBLICLY-21H05711, KAKENHI-PROJECT-21H04758, KAKENHI-PLANNED-21H05253
[Journal Article] Observing the nonvectorial yet cotranslational folding of a multidomain protein, LDL receptor, in the ER of mammalian cells2020
- Author(s)
  Kadokura, H.*, Dazai, Y., Fukuda, Y., Hirai, N., Nakamura, O., Inaba, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA（印刷中）
  
  Volume: －
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26116005
[Journal Article] Observing the nonvectorial yet cotranslational folding of a multidomain protein, LDL receptor, in the ER of mammalian cells2020
- Author(s)
  Kadokura Hiroshi、Dazai Yui、Fukuda Yo、Hirai Naoya、Nakamura Orie、Inaba Kenji
- Journal Title
  
  Proceedings of the National Academy of Sciences, USA
  
  Volume: 117 Issue: 28 Pages: 16401-16408
- DOI
  10.1073/pnas.2004606117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02881, KAKENHI-PROJECT-18H03978
[Journal Article] Characterization of the endoplasmic reticulum-resident peroxidases GPx7 and GPx8 shows the higher oxidative activity of GPx7 and its linkage to oxidative protein folding2020
- Author(s)
  Kanemura S., Sofia E. F., Hirai N., Okumura M., Kadokura H. and Inaba K.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 295 Issue: 36 Pages: 12772-12785
- DOI
  10.1074/jbc.ra120.013607
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16092, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-19H02881
[Journal Article] ヒト由来分泌タンパク質の効率良い生産系の開発に向けて2020
- Author(s)
  門倉　広
- Journal Title
  
  KAGAKU TO SEIBUTSU
  
  Volume: 58 Issue: 8 Pages: 441-443
- DOI
  10.1271/kagakutoseibutsu.58.441
- NAID
  130008070258
- ISSN
  0453-073X, 1883-6852
- Year and Date
  2020-08-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21262, KAKENHI-PROJECT-19H02881
[Journal Article] Methods to identify the substrates of thiol‐disulfide oxidoreductases2019
- Author(s)
  Fujimoto Takushi、Inaba Kenji、Kadokura Hiroshi
- Journal Title
  
  Protein Science
  
  Volume: 28 Issue: 1 Pages: 30-40
- DOI
  10.1002/pro.3530
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-15K07381, KAKENHI-PLANNED-26116005
[Journal Article] IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells2018
- Author(s)
  Yuichi Tsuchiya, Michiko Saito, Hiroshi Kadokura, Jun-ichi Miyazaki, Fumi Tashiro, Yusuke Imagawa, Takao Iwawaki, Kenji Kohno
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 217 Issue: 4 Pages: 1287-1301
- DOI
  10.1083/jcb.201707143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07381, KAKENHI-PROJECT-24228002, KAKENHI-PLANNED-26116006, KAKENHI-PUBLICLY-18H05047, KAKENHI-PROJECT-17H01468, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-17K15134, KAKENHI-PLANNED-26116005
[Journal Article] Identification of the physiological substrates of PDIp, a pancreas-specific protein-disulfide isomerase family member2018
- Author(s)
  Fujimoto Takushi、Nakamura Orie、Saito Michiko、Tsuru Akio、Matsumoto Masaki、Kohno Kenji、Inaba Kenji、Kadokura Hiroshi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 48 Pages: 18421-18433
- DOI
  10.1074/jbc.ra118.003694
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-17H01468, KAKENHI-PROJECT-18H03978, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-15K07381, KAKENHI-PROJECT-17K19606, KAKENHI-PLANNED-26116005
[Journal Article] Structures and functions of protein disulfide isomerase family members involved in proteostasis in the endoplasmic reticulum.2015
- Author(s)
  Okumura M, Kadokura H, Inaba K.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 83 Pages: 314-322
- DOI
  10.1016/j.freeradbiomed.2015.02.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580141, KAKENHI-PROJECT-15K07381, KAKENHI-PUBLICLY-15H01626, KAKENHI-PROJECT-15H04335, KAKENHI-PROJECT-13J04030, KAKENHI-PLANNED-26116005
[Journal Article] Inhibition of the functional interplay between ER oxidoreduclin-1 a (Ero1a) and protein disulfide isomerase (PDI) by the endocrine disruptor2014
- Author(s)
  Okumura M, Kadokura H, Hashimoto S, Yutani K, Kanemura S, Hikima T, Hidaka Y, Ito L, Shiba K, Masui S, Imai D, Imaoka S, Yamaguchi H, Inaba K
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: ２６ Issue: 39 Pages: 27004-27018
- DOI
  10.1074/jbc.m114.564104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J04589, KAKENHI-PROJECT-13J04030, KAKENHI-PROJECT-24510310, KAKENHI-PROJECT-24580141, KAKENHI-PROJECT-25340053, KAKENHI-PLANNED-26116005
[Journal Article] Identification of the redox partners of ERdj5/JPDI, a PDI family member, from an animal tissue.2013
- Author(s)
  Kadokura, H., Saito, M., Tsuru, A., Hosoda, A., Iwawaki, T., Inaba, K., & Kohno, K.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 440 Issue: 2 Pages: 245-250
- DOI
  10.1016/j.bbrc.2013.09.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500496, KAKENHI-PUBLICLY-24113702, KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24580141
[Journal Article] Negative feedback by IRE1β optimizes mucin production in goblet cells2013
- Author(s)
  Tsuru, A., Fujimoto, N., Takahashi, S.,Saito, M., Nakamura, D., Iwano, M., Iwawaki, T., Kadokura, H., Ron, D., Kohno, K
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 110 Pages: 2864-2869
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058010
[Journal Article] A novel mammalian ER-located J-protein, DNAJB14, can accelerate ERAD of misfolded membrane proteins2012
- Author(s)
  Sopha, P., Kadokura, H., Yamamoto, Y.H., Takeuchi, M., Saito, M., Tsuru, A., Kohno, K
- Journal Title
  
  Cell Struct. Funct
  
  Volume: 37 Pages: 177-187
- NAID
  130004137586
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058010
[Journal Article] rearrangement triggered by translocon assembly controls lipopolysaccharide export2012
- Author(s)
  Chng, S.S., Xue, M., Garner, R.A.,Kadokura, H., Boyd, D., Beckwith, J.,Kahne, D. Disulfide
- Journal Title
  
  Science
  
  Volume: 337 Pages: 1665-1668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580092
[Journal Article] Translational pausing ensures membrane-targeting and cytoplasmic splicing of XBP1u mRNA2011
- Author(s)
  Yanagitani, K., Kimata, Y., Kadokura, H., Kohno, K
- Journal Title
  
  Science
  
  Volume: 331 Pages: 586-589
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058010
[Journal Article] Reconstitution and characterization of the unconventional slicing of XBP1u mRNA in vitro2011
- Author(s)
  Shinya, S., Kadokura, H., Imagawa, Y., Inoue, M., Yanagitani, K., and Kohno, K
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39 Pages: 5245-5254
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058010
[Journal Article] A novel ER J-protein DNAJB12 accelerates ER-associated degradation of membraneproteins including CFTR2010
- Author(s)
  Yamamoto, Y., Kimura, T., Momohara, S., Takeuchi, M., Tani, T., Kimata, Y., Kadokura, H., Kohno, K
- Journal Title
  
  Cell Struct. Funct
  
  Volume: 35 Pages: 107-116
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058010
[Journal Article] 分泌タンパク質にジスルフィド結合を形成する仕組み:ジスルフィド結合形成反応中間体の検出2010
- Author(s)
  門倉広
- Journal Title
  
  化学と生物
  
  Volume: 48 Pages: 695-705
- NAID
  10026712890
- Data Source
  KAKENHI-PROJECT-21580092
[Journal Article] Mechanisms of oxidative protein folding in the bacterial cell envelope2010
- Author(s)
  Kadokura, H.
- Journal Title
  
  Antioxid.Redox Signal.
  
  Volume: 13 Pages: 1231-1246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580092
[Journal Article] The L-cysteine/L-cystine shuttle system provides reducing equivalents to the periplasm in Escherichia coli2010
- Author(s)
  Ohtsu, I., Wiriyathanawudhiwong, N.,Morigasaki, S., Nakatani, T., Kadokura H., Takagi H.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 17479-17487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580092
[Journal Article] Mechanisms of oxidative protein folding in the bacterial cell envelope. Antioxid2010
- Author(s)
  Kadokura, H., Beckwith, H.
- Journal Title
  
  Redox Signal
  
  Volume: 13 Pages: 1231-1246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580092
[Journal Article] Detecting folding intermediates of a protein as it passes through the bacterial translocation channel2009
- Author(s)
  Kadokura, H., Beckwith, J.
- Journal Title
  
  Cell
  
  Volume: 138 Pages: 1164-1173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580092
[Journal Article] Detecting folding intermediates of a protein as it passes through the bacterial translocation channel.2009
- Author(s)
  Kadokura, H., Beckwith, J.
- Journal Title
  
  Cell
  
  Volume: 138 Pages: 1164-1173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] ヒト細胞の小胞体中におけるタンパク質の折り畳みを促進する仕組みの解析2023
- Author(s)
  門倉広
- Organizer
  第78回東京工業大学細胞制御工学研究センターコロキウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05711
[Presentation] ヒト細胞の小胞体中におけるタンパク質の折り畳みを促進する仕組みの解析2023
- Author(s)
  門倉　広
- Organizer
  第78回東京工業大学細胞制御工学研究センターコロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K21262
[Presentation] ヒトPDIファミリー酵素によって触媒されるタンパク質のジスルフィド結合形成機構2022
- Author(s)
  門倉　広
- Organizer
  第23回酵素応用シンポジウム研究奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-23K23520
[Presentation] ヒト小胞体膜タンパク質LMF1による膜を介した電子移動メカニズムの解析2022
- Author(s)
  佃竜介，原田楠子，平井直也，東晃太，小林大樹，松本雅記，稲葉謙次，門倉広
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23520
[Presentation] ヒトPDIファミリー酵素によって触媒されるタンパク質のジスルフィド結合形成機構2022
- Author(s)
  門倉広
- Organizer
  第23回酵素応用シンポジウム研究奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05711
[Presentation] ヒトPDIファミリー酵素によって触媒されるタンパク質のジスルフィド結合形成機構2022
- Author(s)
  門倉　広
- Organizer
  第23回酵素応用シンポジウム研究奨励賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-20K21262
[Presentation] 翻訳途上の新生鎖に隠された新しい仕組みによって促進されるタンパク質の折り畳み機構2022
- Author(s)
  門倉　広
- Organizer
  学術変革領域A マルチファセットプロテインズ　第3回領域会議
- Data Source
  KAKENHI-PROJECT-23K23520
[Presentation] 小胞体中におけるマルチドメインタンパク質の翻訳と共役した折り畳みを促進する仕組み2022
- Author(s)
  門倉広
- Organizer
  第22回日本蛋白質科学会年会ワークショップ：細胞内タンパク質世界の新視点-翻訳から液-液相分離まで
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05711
[Presentation] Mechanism of oxidative folding of a multidomain protein, LDL receptor, assisted by PDI family members2022
- Author(s)
  Hao Wu, Naoya Hirai, Yui Dazai, Kenji Inaba, Hiroshi Kadokura
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23520
[Presentation] ヒト小胞体膜タンパク質LMF1による膜を介した電子移動メカニズムの解析2022
- Author(s)
  佃竜介, 原田楠子, 平井直也, 東晃太, 小林大樹, 松本雅記, 稲葉謙次, 門倉広
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H05711
[Presentation] Mechanism of oxidative folding of a multidomain protein, LDL receptor, assisted by PDI family members2022
- Author(s)
  Hao Wu, Naoya Hirai, Yui Dazai, Kenji Inaba, Hiroshi Kadokura
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H05711
[Presentation] 小胞体中におけるマルチドメインタンパク質の翻訳と共役した折り畳みを促進する仕組み2022
- Author(s)
  門倉　広
- Organizer
  第22回日本蛋白質科学会年会ワークショップ：細胞内タンパク質世界の新視点-翻訳から液-液相分離まで
- Invited
- Data Source
  KAKENHI-PROJECT-23K23520
[Presentation] ジスルフィド結合が形成される仕組み：独自のアプローチで迫る、ヒト分泌タンパク質の生細胞内における立体構造形成機構2021
- Author(s)
  門倉　広
- Organizer
  第５回有機・生命・計測科学研究交流セミナー
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] ヒト細胞小胞体関連機能の変化を検出するための鋭敏で簡便なレポーターの開発と機能評価2021
- Author(s)
  原田楠子, 八巻　聡, 平井直也, 中村大祐, 河野憲二, 稲葉謙次, 門倉　広
- Organizer
  第44回日本分子生物学会年会、パシフィコ横浜(横浜、2021年12月2日)
- Data Source
  KAKENHI-PROJECT-20K21262
[Presentation] 細胞内で翻訳合成途上のLDL受容体にジスルフィド結合が形成される仕組み2021
- Author(s)
  門倉広，平井直也，福田洋，太宰結，稲葉謙次
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] ジスルフィド結合が形成される仕組み：独自のアプローチで迫る、ヒト分泌タンパク質の生細胞内における立体構造形成機構2021
- Author(s)
  門倉　広
- Organizer
  第５回有機・生命・計測科学研究交流セミナー
- Data Source
  KAKENHI-PROJECT-20K21262
[Presentation] Visualization and quantification of labile Zn2+ in the acidic subcellular compartments using a small-molecule fluorescent probe2021
- Author(s)
  Yuyin Du, Rong Liu, 小和田俊行, 松井敏高, 門倉広, 稲葉謙次, 水上進
- Organizer
  第32回万有仙台シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] ヒト細胞小胞体関連機能の変化を検出するための鋭敏で簡便なレポーターの開発と機能評価2021
- Author(s)
  原田楠子, 八巻　聡, 平井直也, 中村大祐, 河野憲二, 稲葉謙次, 門倉　広
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H05711
[Presentation] Observing the cotranslational disulfide rearrangement in a cell surface multidomain protein, LDL receptor, in the ER of mammalian cells2021
- Author(s)
  Hiroshi Kadokura
- Organizer
  Functional Disulfides in Health & Disease 2021, Weizmann Institute of Science, Israel, Web開催
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] 細胞内で翻訳合成途上のLDL受容体にジスルフィド結合が形成される仕組み2021
- Author(s)
  門倉広，平井直也，福田洋，太宰結，稲葉謙次
- Organizer
  第94回日本生化学大会, Web開催
- Data Source
  KAKENHI-PUBLICLY-21H05711
[Presentation] Biochemical characterizations of ER-resident peroxidases, GPx7 and GPx8, reveal their distinct oxidative activities.2020
- Author(s)
  Shingo Kanemura, Elza Firdiani Sofia, Naoya Hirai, Masaki Okumura, Hiroshi Kadokura and Kenji Inaba
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] ヒト細胞小胞体機能の低下を鋭敏に検出するレポーターの開発と応用2020
- Author(s)
  八巻　聡、河野憲二、稲葉謙次、門倉　広
- Organizer
  東北大学大学院理学・生命科学 2 研究科合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] Mechanistic basis and physiological functions of GPx7 and GPx8, newly identified PDI oxidases in the mammalian endoplasmic reticulum2019
- Author(s)
  Elza Firdiani Sofia, Shingo Kanemura, Hiroshi Kadokura, Masaki Okumura, Kenji Inaba.
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] Mechanistic basis and physiological functions of GPx7 and GPx8, newly identified PDI oxidases, in the mammalian endoplasmic reticulum2019
- Author(s)
  Elza Firdiani Sofia, Shingo Kanemura, Hiroshi Kadokura, Masaki Okumura, Kenji Inaba
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] ヒト細胞小胞体機能の低下を鋭敏に検出するレポーターの開発と応用2019
- Author(s)
  八巻聡、河野憲二、稲葉謙次、門倉広
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] ヒト細胞小胞体機能の低下を鋭敏に検出するレポーターの開発と応用2019
- Author(s)
  八巻聡、河野憲二、稲葉謙次、門倉広
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] PDIファミリーメンバーP5の新規構造と機能2019
- Author(s)
  奥村正樹, 金村進吾, 松崎元紀, 木下岬, 荒井堅太, 平山千尋, 天貝佑太, 門倉広, 秋山修志, 稲葉謙次
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H02881
[Presentation] Elucidation of physiological function of PDIp, a pancreas-specific protein disulfide isomerase family member protein2018
- Author(s)
  Takushi Fujimoto, Orie Nakamura, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, and Hiroshi Kadokura
- Organizer
  International Symposium on“Proteins; from the Cradle to the Grave”
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Physiological substrates of PDIp, a pancreas-specific protein disulfide isomerase family member protein2018
- Author(s)
  Takushi Fujimoto, Orie Nakamura, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, Hiroshi Kadokura
- Organizer
  FASEB conference, Protein Folding in the Cell
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Observing Co-translational Oxidative Folding of a Cell Surface Membrane Protein in Mammalian Cell2018
- Author(s)
  Yo Fukuda, Yui Dazai, Orie Nakamura, Kenji Inaba, Hiroshi Kadokura
- Organizer
  CLS, Tokyo Tech, International Forum 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Elucidation of physiological function of PDIp, a pancreas-specific protein disulfide isomerase family member protein2018
- Author(s)
  Takushi Fujimoto, Orie Nakamura, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, and Hiroshi Kadokura
- Organizer
  International Symposium on“Proteins; from the Cradle to the Grave”, Shiga, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Observing co-translational oxidative folding of a cell surface protein in the ER of mammalian cells2018
- Author(s)
  Yo Fukuda, Yui Dazai, Naoya Hirai, Orie Nakamura, Kenji Inaba, Hiroshi Kadokura
- Organizer
  CLS, Tokyo Tech. International Forum 2018 “Redox regulation of protein functions, transcription, translation and folding、東京工業大学キャンパス・イノベーションセンター
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Physiological function of PDIp, a pancreas-specific protein disulfide isomerase family member protein2018
- Author(s)
  Takushi Fujimoto, Orie Nakamura, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, Hiroshi Kadokura
- Organizer
  5th CWRU-Tohoku Joint Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Mechanistic basis of hydrogen peroxide-dependent PDI family oxidation catalyzed by GPx7 and GPx82018
- Author(s)
  Elza Firdiani Sofia, Shingo Kanemura, Hiroshi Kadokura, Masaki Okumura, Kenji Inaba
- Organizer
  International Symposium on New Horizon in Advanced Materials Tohoku University-Taipei Tech Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Physiological function of PDIp, a pancreas-specific protein disulfide isomerase family member protein2018
- Author(s)
  Takushi Fujimoto, Orie Nakamura, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, Hiroshi Kadokura
- Organizer
  5th CWRU-Tohoku Joint Workshop, Sendai, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Mechanistic basis of hydrogen peroxide-dependent PDI family oxidation catalyzed by GPx7 and GPx82018
- Author(s)
  Elza Firdiani Sofia, Shingo Kanemura, Hiroshi Kadokura, Masaki Okumura, Kenji Inaba
- Organizer
  International Symposium on Proteins: From the Cradle to the Grave
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Observing co-translational oxidative folding of a cell surface protein in the ER of mammalian cells2018
- Author(s)
  Yo Fukuda, Yui Dazai, Naoya Hirai, Orie Nakamura, Kenji Inaba, and Hiroshi Kadokura
- Organizer
  International Symposium on“Proteins; from the Cradle to the Grave”
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Physiological substrates of PDIp, a pancreas-specific protein disulfide isomerase family member protein2018
- Author(s)
  Takushi Fujimoto, Orie Nakamura, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, Hiroshi Kadokura
- Organizer
  FASEB conference Protein Folding in the Cell, Olean, NY, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Observing co-translational oxidative folding of a cell surface protein in the ER of mammalian cell2018
- Author(s)
  Hiroshi Kadokura
- Organizer
  International Symposium on“Proteins; from the Cradle to the Grave”, Shiga, Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 哺乳動物細胞小胞体内におけるLDL受容体新生ポリペプチド鎖の酸化的フォールディング機構の解析2017
- Author(s)
  太宰　結、中村織江、稲葉謙次、門倉　広
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Observing cotranslational oxidative folding of a cell surface membrane protein2017
- Author(s)
  Hiroshi Kadokura
- Organizer
  Microbial Genetics and Genomics VII
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] LDL受容体の新生ポリペプチド鎖におけるジスルフィド結合形成機構の解析2017
- Author(s)
  福田洋，太宰結，中村織江，稲葉謙次，門倉広
- Organizer
  2017年度　生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 哺乳動物細胞小胞体内におけるLDL受容体新生ポリペプチド鎖の酸化的フォールディング機構の解析2017
- Author(s)
  太宰　結、中村織江、稲葉謙次、門倉　広
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Cotranslational oxidative folding of a cell surface membrane protein in mammalian cells2017
- Author(s)
  Yui Dazai, Orie Nakamura, Yo Fukuda, Kenji Inaba, Hiroshi Kadokura
- Organizer
  International Symposium on Protein Quality Control
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Cotranslational oxidative folding of a cell surface membrane protein in mammalian cells2017
- Author(s)
  Yui Dazai, Orie Nakamura, Yo Fukuda, Kenji Inaba, Hiroshi Kadokura
- Organizer
  International Symposium on Protein Quality Control
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Observing cotranslational oxidative folding of a cell surface membrane protein2017
- Author(s)
  Hiroshi Kadokura
- Organizer
  Microbial Genetics and Genomics VI
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] LDL受容体の新生ポリペプチド鎖におけるジスルフィド結合形成機構の解析2017
- Author(s)
  福田洋，太宰結，中村織江，稲葉謙次，門倉広
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 膵特異的に発現しているPDIファミリータンパク質(PDIp)の生理的な機能の解析2016
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、松本雅記、河野憲二、稲葉謙次、門倉　広
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台国際センター　東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Mechanisms of oxidative folding of newly-synthesized LDL receptor in the ER of mammalian cells2016
- Author(s)
  Yui Dazai, Kenji Inaba, Hiroshi Kadokura
- Organizer
  Nascent chain biology meeting
- Place of Presentation
  富士レークホテル（山梨県富士河口湖町）
- Year and Date
  2016-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 膵臓β細胞におけるIRE1α経路の生理的活性化はプロインスリンの酸化的折りたたみ酵素の発現維持に働く2016
- Author(s)
  土屋雄一、斉藤美知子、門倉広、芝陽子、宮崎純一、岩脇隆夫、河野憲二
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Observing disulfide bond formation in a cell surface protein as the polypeptide chain elongates from the ribosome in mammalian cells2016
- Author(s)
  Kadokura, H
- Organizer
  Nascent chain biology meeting 2016
- Place of Presentation
  富士レークホテル（山梨県富士河口湖町）
- Year and Date
  2016-09-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 哺乳動物分泌蛋白質の新生鎖上にジスルフィド結合を形成する仕組み2016
- Author(s)
  門倉　広、稲葉謙次
- Organizer
  第16回　日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Mechanisms of oxidative folding of newly-synthesized LDL receptor in the ER of mammalian cells2016
- Author(s)
  Dazai, Y., Inaba, K. and Kadokura, H.
- Organizer
  Nascent Chain Biology 2016
- Place of Presentation
  富士レークホテル（山梨県富士河口湖町）
- Year and Date
  2016-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 哺乳動物分泌蛋白質の新生鎖上にジスルフィド結合を形成する仕組み2016
- Author(s)
  門倉　広、稲葉謙次
- Organizer
  第１６回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-06-07
- Invited
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 膵特異的に発現しているPDIファミリータンパク質(PDIp)の生理的な基質の同定2016
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、松本雅記、河野憲二、稲葉謙次、門倉広
- Organizer
  第１６回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Mechanisms of disulfide bond formation in a newly- synthesized cell surface protein2016
- Author(s)
  Yui Dazai, Kenji Inaba, Hiroshi Kadokura
- Organizer
  The 9th Tohoku University Campus Asia Chemistry Summer School
- Place of Presentation
  東北大学青葉山北キャンパス（宮城県仙台市）
- Year and Date
  2016-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 膵特異的に発現しているPDIファミリータンパク質(PDIp)の生理的な機能の解析2016
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、松本雅記、河野憲二、稲葉謙次、門倉　広
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 膵特異的に発現しているPDIファミリータンパク質(PDIp)の生理的な基質の同定2016
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、松本雅記、河野憲二、稲葉謙次、門倉　広
- Organizer
  第16回　日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 哺乳動物細胞小胞体におけるLDLレセプター新生ポリペプチド鎖の酸化的フォールディング機構2016
- Author(s)
  太宰　結、稲葉謙次、門倉広
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Physiological function of pancreas-specific PDI family protein (PDIp)2016
- Author(s)
  Takushi Fujimoto, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, Hiroshi Kadokura
- Organizer
  Nascent chain biology meeting
- Place of Presentation
  富士レークホテル（山梨県富士河口湖町）
- Year and Date
  2016-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Physiological function of pancreas-specific PDI family protein (PDIp)2016
- Author(s)
  Fujimoto, T., Saito, M., Tsuru, A., Matsumoto, M., Kohno, K., Inaba, K. and Kadokura, H.
- Organizer
  Nascent Chain Biology 2016
- Place of Presentation
  富士レークホテル（山梨県富士河口湖町）
- Year and Date
  2016-09-01
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] Physiological function of pancreas-specific PDI family protein (PDIp)2016
- Author(s)
  Takushi Fujimoto, Michiko Saito, Akio Tsuru, Masaki Matsumoto, Kenji Kohno, Kenji Inaba, Hiroshi Kadokura
- Organizer
  The 9th Tohoku University Campus Asia Chemistry Summer School
- Place of Presentation
  東北大学青葉山キャンパス（宮城県仙台市）
- Year and Date
  2016-08-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Observing disulfide bond formation in a cell surface protein as the polypeptide chain elongates from the ribosome in mammalian cells2016
- Author(s)
  Hiroshi Kadokura
- Organizer
  Nascent chain biology meeting
- Place of Presentation
  富士レークホテル（山梨県富士河口湖町）
- Year and Date
  2016-09-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 哺乳動物細胞小胞体におけるLDLレセプター新生ポリペプチド鎖の酸化的フォールディング機構2016
- Author(s)
  太宰　結、稲葉謙次、門倉　広
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Mechanisms of disulfide bond formation in nascent polypeptide chains in the ER of mammalian cells2015
- Author(s)
  Kadokura, H
- Organizer
  Symposium: From cytosol to ER; Translation, translocation and modification
- Place of Presentation
  東北大学片平キャンパス（宮城県仙台市）
- Year and Date
  2015-11-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 膵臓特異的に発現しているPDIファミリータンパク質(PDIp)の生理的な機能の解析2015
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、松本雅記、河野憲二、稲葉謙次、門倉広
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 膵臓特異的に発現しているPDIファミリータンパク質(PDIp)の生理的な機能の解析2015
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、松本雅記、河野憲二、稲葉謙次、門倉広
- Organizer
  第38回　日本分子生物学会年会　第88回　日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] インスリンと相互作用するPDIファミリータンパク質の同定2015
- Author(s)
  金谷健太郎、土屋雄一、河野憲二、稲葉謙次、門倉広
- Organizer
  第67回　日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 膵特異的に発現するPDIファミリータンパク質(PDIp)の生理的な基質の同定2015
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、河野憲二、稲葉謙次、門倉広
- Organizer
  日本生化学会東北支部第81回例会
- Place of Presentation
  東北大学　片平キャンパス（仙台市）
- Year and Date
  2015-05-09
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] インスリンと相互作用するPDIファミリータンパク質の同定2015
- Author(s)
  金谷健太郎、土屋雄一、河野憲二、稲葉謙次、門倉広
- Organizer
  日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] Mechanisms of disulfide bond formation in nascent polypeptide chains in the ER of mammalian cells2015
- Author(s)
  Hiroshi Kadokura
- Organizer
  Symposium: From cytosol to ER: Translation, translocation and modification
- Place of Presentation
  東北大学　片平キャンパス（仙台市）
- Year and Date
  2015-11-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 膵特異的に発現するPDIファミリータンパク質(PDIp)の生理的機能の解析2015
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、河野憲二、稲葉謙次、門倉広
- Organizer
  第67回　日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 膵特異的に発現するPDIファミリータンパク質(PDIp)の生理的機能の解析2015
- Author(s)
  藤本拓志、斎藤美知子、都留秋雄、河野憲二、稲葉謙次、門倉広
- Organizer
  日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K07381
[Presentation] 分泌タンパク質新生ポリペプチド鎖にジスルフィド結合を形成する仕組み2014
- Author(s)
  門倉　広、稲葉謙次
- Organizer
  日本生化学会年会
- Place of Presentation
  京都国際会館、京都
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PLANNED-26116005
[Presentation] 哺乳動物細胞小胞体におけるジスルフィド結合形成を解析する為の新規レポーターの作成2013
- Author(s)
  門倉広、河野憲二
- Organizer
  日本農芸化学会2012 年度大会
- Place of Presentation
  京都女子大学
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] 小胞体機能を解析するための新規レポーターの開発2012
- Author(s)
  門倉広
- Organizer
  2012年度国立遺伝学研究所研究会
- Place of Presentation
  国立遺伝学研究所(招待講演)
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] 哺乳動物細胞小胞体内におけるジスルフィド結合形成能力の低下を検出する為の鋭敏なアッセイ系の構築2012
- Author(s)
  門倉広
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] 哺乳動物細胞小胞体内におけるジスルフィド結合形成能力の低下を検出する為の鋭敏なアッセイ系の構築2012
- Author(s)
  門倉広,河野憲二
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] Developing a genetic assay for the analysis of disulfide bond formation in the ER of mammalian cells2011
- Author(s)
  Kadokura, H.
- Organizer
  Microbial Genetics and Genomics V
- Place of Presentation
  Harvard Medical School in Boston; Oral
- Year and Date
  2011-05-01
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] Ribosomal stalling promotes mRNA splicing on the endoplasmic reticulum2011
- Author(s)
  Kota Yanagitani, Yukiko Yokota, Yukio Kimata, Hiroshi Kadokura, Kenji Kohno
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] 反応中間体の解析から見えてきた、生体内における分泌蛋白質の酸化的フォールディングの仕組み2011
- Author(s)
  門倉広、Jon Beckwith、河野憲二
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] Mechanisms of oxidative protein folding in vivo : Novel features revealed by the analysis of disulfide-linked enzyme-substrate complexes2010
- Author(s)
  Kadokura, H.
- Organizer
  第3回タンパク質社会の国際会議
- Place of Presentation
  ホテル日航奈良(国際会議招待講演)
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] 生体内における分泌タンパク質ジスルフィド結合形成反応中間体の解析2010
- Author(s)
  門倉広、河野憲二、Jon Beckwith
- Organizer
  日本農芸化学会2010 年度大会
- Place of Presentation
  東京大学駒場キャンパス
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] 生体内における分泌タンパク質ジスルフィド形成反応中間体の解析2010
- Author(s)
  門倉広
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] 生体内で分泌蛋白質にジスルフィド結合を形成する仕組み:ジスルフィド結合形成反応中間体の検出およびその解析2010
- Author(s)
  門倉広
- Organizer
  第10回日本蛋白質学会大会
- Place of Presentation
  札幌コンベンションセンター(招待講演)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] 分泌蛋白質ジスルフィド結合形成中間体の解析から明らかになった酵素・基質間相互作用の制御2010
- Author(s)
  門倉広
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] 生体内における分泌タンパク質ジスルフィド結合形成反応中間体の解析2010
- Author(s)
  門倉広、河野憲二、Beckwith, Jon
- Organizer
  日本農芸化学会
- Place of Presentation
  東京大学駒場キャンパス(東京都)
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] Mechanisms of oxidative protein folding in vivo: Novel features revealed by the analysis of disulfide- linked enzyme-substrate complexes2010
- Author(s)
  Kadokura, H.
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  Hotel Nikko Nara;Oral, Invited presentation
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] 生体内で分泌蛋白質にジスルフィド結合を形成する仕組み:ジスルフィド結合形成反応中間体の検出およびその解析2010
- Author(s)
  門倉広
- Organizer
  第10回日本蛋白質学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] Mechanisms of oxidative protein folding in vivo : Novel features revealed by the analysis of disulfide-linked enzyme-substrate complexes2010
- Author(s)
  Hiroshi Kadokura
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  ホテル日航奈良
- Year and Date
  2010-09-13
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] タンパク質ジスルフィド結合形成反応中間体の検出とその解析2008
- Author(s)
  門倉広
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] タンパク質ジスルフィド結合形成反応中間体の検出とその解析2008
- Author(s)
  門倉広
- Organizer
  BMB2008(第31回日本分子生物学会年会・第81回日本生物学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PLANNED-19058010
[Presentation] 分泌タンパク質新生ポリペプチド鎖の酸化的フォールディングの解析
- Author(s)
  門倉　広、稲葉謙次
- Organizer
  第14回　日本蛋白質学会大会
- Place of Presentation
  横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-24580141
[Presentation] 内分泌撹乱物質によるEro1-PDI経路の阻害機構
- Author(s)
  奥村　正樹, 橋本　翔子, 油谷　克英, 金村　進吾, 引間　孝明, 門倉　広, 今岡　進, 山口　宏, 稲葉　謙次
- Organizer
  第14回　日本蛋白質科学会
- Place of Presentation
  横浜
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-24580141
[Presentation] 反応中間体の解析から見えてきた、生体内における分泌蛋白質の酸化的フォールディングの仕組み
- Author(s)
  門倉　広
- Organizer
  日本生化学会大会
- Place of Presentation
  京都国際会館
- Invited
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] 分泌タンパク質新生ポリペプチド鎖にジスルフィド結合を形成する仕組み
- Author(s)
  門倉　広、稲葉謙次
- Organizer
  第87回　日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-24580141
[Presentation] ERdj5(JPDI)基質候補タンパク質のマウス個体組織からの網羅的同定
- Author(s)
  門倉　広、斉藤美知子、都留秋雄、稲葉謙次、河野憲二
- Organizer
  第66回　日本細胞生物学会
- Place of Presentation
  奈良
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24580141
[Presentation] Towards the understanding of thiol-dependent redox networks in the ER of mammalian cells
- Author(s)
  Hiroshi Kadokura
- Organizer
  Microbial Genetics and Genomics VI
- Place of Presentation
  フランス・パリ・パスツール研究所
- Year and Date
  2014-04-16 – 2014-04-18
- Data Source
  KAKENHI-PROJECT-24580141
[Presentation] 小胞体膜タンパク質DNAJB12の活性制御におけるジスルフィド結合の影響
- Author(s)
  佐藤仁美、井上道雄、保田裕貴、山本洋平、門倉　広、稲葉謙次、河野憲二
- Organizer
  第66回　日本細胞生物学会
- Place of Presentation
  奈良
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24580141
[Presentation] 哺乳動物細胞小胞体に局在するERdj5(JPDI)の生理的基質候補タンパク質の網羅的解析
- Author(s)
  門倉　広
- Organizer
  日本農芸化学会
- Place of Presentation
  明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-24580141
[Presentation] 哺乳動物細胞小胞体におけるジスルフィド結合形成を解析する為の新規レポーターの作成
- Author(s)
  門倉　広
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学
- Data Source
  KAKENHI-PROJECT-21580092
[Presentation] 哺乳動物細胞小胞体内におけるジスルフィド結合形成能力の低下を検出する為の鋭敏なアッセイ系の構築
- Author(s)
  門倉　広
- Organizer
  日本生化学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24580141

1. YAMASAKI Makari (60011889)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KOHNO Kenji (50142005)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. SAITO Michiko (40379558)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. YODA Koji (20143406)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TSURU Akio (80273861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. TERADA Kazutoyo (00253724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KIMATA Yukio (60263448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. YANAGITANI Kota (70614775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. Kenji Inaba (10423039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
10. YAMAMOTO Yohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 金村進吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 松本雅記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kadokura Hiroshi 門倉 広

KADOKURA Hiroshi 門倉 広

門倉 広 カドクラ ヒロシ

Research Projects

Research Products

Co-Researchers

ヒト小胞体におけるタンパク質の正確で迅速なジスルフィド結合形成を可能にする仕組みPrincipal Investigator

Principal Investigator

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翻訳途上の新生鎖に隠された新しい仕組みによって促進されるタンパク質の折り畳み機構Principal Investigator

Principal Investigator

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Screening for small molecule compounds that inhibit the biosynthesis of a specific cell-surface proteinPrincipal Investigator

Principal Investigator

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Review Section

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Mechanism of protein disulfide bond formation in the ER of human cellsPrincipal Investigator

Principal Investigator

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Review Section

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Mechanisms of protein disulfide bond formation in the ER of mammalian cellsPrincipal Investigator

Principal Investigator

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Elucidation of mechanisms underlying disulfide bond formation in nascent chains

Principal Investigator

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Mechanisms of protein disulfide bond formation in the ER of mammalian cellsPrincipal Investigator

Principal Investigator

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Mechanisms of oxidative protein folding in the periplasm of E. coliPrincipal Investigator

Principal Investigator

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Analyses of the physiological roles of unfolded protein response

Principal Investigator

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分泌蛋白質のジスルフィド結合形成に必要な大腸菌内膜蛋白質DsbBの機能解析Principal Investigator

Principal Investigator

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ジスルフィド結合形成促進酵素の大腸菌表層へのターゲティングPrincipal Investigator

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Research Institution

異種タンパク質の大腸菌ペリプラズムへの分泌生産にともなうストレス応答の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

異常分泌タンパク質のペリプラズム生産に対する大腸菌のストレス応答の解析Principal Investigator

Principal Investigator

Project Period (FY)

Kadokura Hiroshi 門倉広

KADOKURA Hiroshi 門倉広

門倉広カドクラヒロシ