HIDAI Chiaki 日だい智明

… Alternative Names

日だい智明ヒダイチアキ

日〓智明ヒダイチアキ

日台智明ヒダイトモアキ

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Researcher Number	70228732
Other IDs
External Links
Affiliation (Current)	2025: 日本大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 日本大学, 医学部, 教授 2017 – 2018: 日本大学, 医学部, 准教授 2000 – 2004: 日本大学, 医学部, 講師 1998 – 1999: 東京女子医科大学, 医学部, 助手 1994: 東京女子医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Basic Section 56010:Neurosurgery-related / Basic Section 54010:Hematology and medical oncology-related / Neurosurgery / General anatomy (including Histology/Embryology) Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Plastic surgery / General physiology
Keywords	Principal Investigator 凝固因子 / 炎症 / 血管内皮細胞 / STAT3 / activation peptide / 凝固第IX因子 / 心筋 / 発生 / BDNF / 治癒 … More / 脳 / interleukin 6 / 虚血 / 抗炎症作用 / 凝固第九因子 / 血液凝固因子 / 炎症反応 / 脳梗塞 / 脳浮腫 / blood brain barrier / 血液凝固第九因子 / 治療 / 凝固第９因子 / 細胞骨格 / 外傷性脳挫傷 / チュブリン / 頭部外傷 / 血液脳関門 / 血管透過性 / 脳挫傷 / Angiogenesis / Development / Endothelia cell / 肥大 / 形態形成 / 血管新生 / FGF / 分化 / TGFβ1 / 細胞外基質 / 心臓 … More Except Principal Investigator preconditioning / 内耳細胞 / Caspase-3 / Beclin-1 / necroptosis / オートファジー / apotosis / 前庭細胞 / 耳鳴 / めまい / 内耳培養細胞 / 小胞体ストレス / エクソソーム / 線維筋痛症 / 第Ⅸ凝固因子由来上皮成長因子（EGF-F9） / 第９凝固因子由来上皮成長因子 / 凝固因子 / 被膜 / 線維増殖性疾患 / 免疫不全マウス / 移植 / 第XI凝固因子由来上皮成長因子 / 被膜拘縮 / インプラント / 第Ⅸ凝固因子由来上皮成長因子 / DFAT / 脱分化脂肪細胞 / 肥厚性瘢痕 / ケロイド / reperfusion / A1 receptor / adenosine / ventricular muscle / アデノシンA_1受容体 / 心筋虚血 / 虚血再灌流 / A_1受容体 / アデノシン / 心室筋 / ディスコイディン / 血管発生 / 心臓発生 / 心内膜 / 内皮細胞 Less

Protective action of coagulation factor IX-derived peptide on neural tissue.Principal Investigator
- Principal Investigator
  
  日だい智明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nihon University
Activation peptide of coagulation factor IX protects vascular endothelial cellsPrincipal Investigator
- Principal Investigator
  
  HIDAI Chiaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nihon University
Research of the mechanism of exosome propagation for fibromyalgia accompanied with the cochlea and vestibular symptoms
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Nihon University
The function of activation peptide of coagulation factor IXPrincipal Investigator
- Principal Investigator
  
  HIDAI Chiaki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Nihon University
Development of a new keloid treatment using dedifferentiated fat cells and coagulation factor-derived protein.
- Principal Investigator
  
  NAKAZAWA Hiroaki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nihon University
The mechanism underlying the upregulation of A1R mRNA expression in non-ischemic raight ventricle by the ischemia of left ventricle
- Principal Investigator
  
  KOKUBUN Shinichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Nihon University
Function of Dell in Embryonic DevelopmentPrincipal Investigator
- Principal Investigator
  
  HIDAI Chiaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Nihon University School of Medicine
心筋移植療法のための心筋分化誘導に関する研究Principal Investigator
- Principal Investigator
  
  日臺智明
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Nihon University
  Tokyo Women's Medical University
新しい細胞外基質蛋白del-1の心臓発生における機能の研究Principal Investigator
- Principal Investigator
  
  日〓智明, 日臺智明
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Women's Medical University
内皮細胞分化調節遺伝子の心臓発生、分化に対する役割
- Principal Investigator
  
  KAWANA Masatoshi
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Women's Medical University

All 2023 2022 2021 2020 2019 2018 2003

All Journal Article Presentation Patent

[Journal Article] Combination Cancer Therapy of a Del1 Fragment and Cisplatin Enhanced Therapeutic Efficiency In Vivo.2021
- Author(s)
  Hisataka Kitano, Yoh Masaoka, Atsushi Mamiya, Yusuke Fujiwara, Toshio Miki, Chiaki Hidai.
- Journal Title
  
  In Vivo
  
  Volume: 35 Issue: 2 Pages: 779-791
- DOI
  10.21873/invivo.12318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10850, KAKENHI-PROJECT-18K09800
[Journal Article] Activation peptide of coagulation factor IX improves the prognosis after traumatic brain injury2021
- Author(s)
  Yuusuke Fujiwara , Hisataka Kitano , Takamitsu Yamamoto , Shinichiro Kokubun , Chiaki Hidai
- Journal Title
  
  Biochem Biophys Res Commun .
  
  Volume: 569 Pages: 35-40
- DOI
  10.1016/j.bbrc.2021.06.089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08380
[Journal Article] 線維増殖性疾患に対する第9凝固因子由来上皮成長因子の影響に関する検討2020
- Author(s)
  樫村勉, 日台智明, 副島一孝, 菊池雄二, 仲沢弘明
- Journal Title
  
  瘢痕・ケロイド治療ジャーナル
  
  Volume: 14 Pages: 25-27
- Data Source
  KAKENHI-PROJECT-17K11556
[Journal Article] An Epidermal Growth Factor Motif of Developmental Endothelial Locus 1 Protein Inhibits Efficient Angiogenesis in Explanted Squamous Cell Carcinoma In Vivo2020
- Author(s)
  Hisataka Kitano, Yoh Masaoka, Atsushi Mamiya, Yusuke Fujiwara, Toshio Miki, Chiaki Hidai.
- Journal Title
  
  Rev Invest Clin
  
  Volume: 73 Issue: 1 Pages: 39-51
- DOI
  10.24875/ric.20000375
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10850
[Journal Article] Casper-8 Regulates Endoplasmic Reticulum Stress-Induced Necroptosis Independent of the Apotosis Pathway in Auditor Cells2019
- Author(s)
  Kishino A, Hayashi K, Maeda M, Jike T, Hidai C, Nomura Y, Oshima T.
- Journal Title
  
  Int J. Mol. Sci.
  
  Volume: 20(23) Issue: 23 Pages: 5896-5896
- DOI
  10.3390/ijms20235896
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09358, KAKENHI-PROJECT-19K09899, KAKENHI-PROJECT-19K09916, KAKENHI-PROJECT-19K18747
[Journal Article] FGF-I enhanced cardiogenesis in differentiating embryonal carcinoma cell cultures, which was opposite to the effect of FGF-2.2003
- Author(s)
  Chiaki Hidai et al.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology 35
  
  Pages: 421-425
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590193
[Journal Article] FGF-1 enhanced cardiogenesis in differentiating Embryonal carcinoma cell cultures, which was opposite to the effect of FGF-2.2003
- Author(s)
  Chiaki Hidai et al.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology 35
  
  Pages: 421-425
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590193
[Journal Article] Specific regulation of nucleocytoplasmic distribution of poly(C)-binding protein gene mRNA in mouse development.2003
- Author(s)
  Chiaki Hidai et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 309
  
  Pages: 339-343
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590193
[Patent] 抗炎症剤及び医薬組成物2022
- Inventor(s)
  日台智明
- Industrial Property Rights Holder
  日台智明
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-191421
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K08380
[Presentation] Suppression of multiple signaling pathways by a peptide that inhibit clustering of lipid rafts.2023
- Author(s)
  Yoh Masaoka, Hisataka Kitano, Yusuke Fujiwara, Kazuhiro Komiyama, Chiaki Hidai
- Organizer
  American Society of Cell Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08380
[Presentation] 当科における熱傷後瘢痕に対する再生医療の試み2020
- Author(s)
  樫村　勉、日台智明、菅原　隆、長崎敬仁、吉田光徳、菊池雄二、副島一孝、仲沢弘明
- Organizer
  第46回日本熱傷学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K11556
[Presentation] 当科におけるインプラント周囲被膜の基礎研究. 第２９回日本形成外科学会基礎学術集会2020
- Author(s)
  樫村　勉、日台智明、菅原　隆、吉田光徳、菊池雄二、副島一孝
- Organizer
  第２９回日本形成外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11556
[Presentation] Caspase-8 regulates ER stress-induced necroptosis in auditory cells2019
- Author(s)
  Akihiro Kishino, Ken Hayashi, Chiaki Hidai, Yasuyuki Nomura, Takeshi Oshima
- Organizer
  AAO-HNSF Annual Meeting & OTO EXPO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09358
[Presentation] A coagulation factor IX peptide regulates endothelial barrier function in brain2019
- Author(s)
  藤原祐輔、真宮淳、北野尚孝、日台智明
- Organizer
  口腔科学会
- Data Source
  KAKENHI-PROJECT-17K10850
[Presentation] Coagulation factor IX peptide regulates endothelial barrier function and improves prognosis in traumatic brain injury (TBI) model2018
- Author(s)
  Yuusuke Fujiwara, Hisataka Kitano, Atsushi Mamiya, Chiaki Hidai, Shinichiro Kokubun
- Organizer
  American Society of Cell Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10850
[Presentation] 第9凝固因子由来上皮成長因子（EGF-F9）による被膜形成の抑制効果についての検討2018
- Author(s)
  樫村　勉、日台智明、堀米迪生、吉田光徳屋形有美、副島一孝、菊池雄二、仲沢弘明
- Organizer
  第61回形成外科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K11556
[Presentation] Effect of The First Epidermal Growth Factor (EGF) Motif of Coagulation Factor 9 (EGF-F9) on Capsular Formation Around Silicone Implants.2018
- Author(s)
  Kashimura T, Hidai C, Soejima K, Kikuchi Y, Nakazawa H
- Organizer
  American Society of Plastic Surgery The Meeting,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11556

1. KAWANA Masatoshi (20152978)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KOKUBUN Shinichiro (20153520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NAKAZAWA Hiroaki (60180270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. NOMURA Yasuyuki (20297815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 市川健一郎 (70232395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 上田みどり (10184938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 木全心一 (40101860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 日臺智明 (30266720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 副島一孝 (00246589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 樫村勉 (20570740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 松本太郎 (50366580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 弓削類 (20263676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 村上正人 (60142501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIDAI Chiaki 日だい 智明

日だい 智明 ヒダイ チアキ

日〓 智明 ヒダイ チアキ

日台 智明 ヒダイ トモアキ

Research Projects

Research Products

Co-Researchers

Protective action of coagulation factor IX-derived peptide on neural tissue.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Activation peptide of coagulation factor IX protects vascular endothelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research of the mechanism of exosome propagation for fibromyalgia accompanied with the cochlea and vestibular symptoms

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The function of activation peptide of coagulation factor IXPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new keloid treatment using dedifferentiated fat cells and coagulation factor-derived protein.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism underlying the upregulation of A1R mRNA expression in non-ischemic raight ventricle by the ischemia of left ventricle

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of Dell in Embryonic DevelopmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋移植療法のための心筋分化誘導に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい細胞外基質蛋白del-1の心臓発生における機能の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内皮細胞分化調節遺伝子の心臓発生、分化に対する役割

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Combination Cancer Therapy of a Del1 Fragment and Cisplatin Enhanced Therapeutic Efficiency In Vivo.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation peptide of coagulation factor IX improves the prognosis after traumatic brain injury2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 線維増殖性疾患に対する第9凝固因子由来上皮成長因子の影響に関する検討2020

Author(s)

Journal Title

Data Source

HIDAI Chiaki 日だい智明

日だい智明ヒダイチアキ

日〓智明ヒダイチアキ

日台智明ヒダイトモアキ