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YAMADA Harutaka  山田 晴生

ORCIDConnect your ORCID iD *help
Researcher Number 70230472
External Links
Affiliation (based on the past Project Information) *help 2007 – 2008: 愛知医科大学, 医学部, 准教授
2006: 愛知薬科大学, 医学部, 講師
1999 – 2006: Aichi Med. Univ. / 1st Dept. of Internal Med. / associate professor, 医学部, 講師
1999: 岐阜薬科大学, 医学部, 講師
1998: 愛知医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Kidney internal medicine
Except Principal Investigator
Biological pharmacy / Medical pharmacy
Keywords
Principal Investigator
mesangial cell / superoxide dismutase / reactive oxygen species / differentiation / gene regulation / nephritis / oxygen radicals / superoxide / chemokine / Oxygen Radical species … More / Monoclonal Antibody / Oxygen Radical Species / Mesangial Cell / Superoxide Dismutase … More
Except Principal Investigator
cAMP / 糖尿病 / スーパーオキシドジスムターゼ / Active oxygens / Heparin / Diabetes mellitus / Hemodialysis patients / Extracellular-superoxide dismutase / 一酸化窒素 / 糖尿病性腎症 / 糸球体 / ホモシステイン / 加齢 / 活性酸素 / ヘパリン / 透析患者 / 細胞外型スーパーオキシドジスムターゼ / 血管平滑筋細胞 / 腫瘍壞死因子 / インスリン抵抗性 / 腎尿細管細胞 / 動脈硬化 / メタボリックシンドローム / 酸化ストレス / 脂肪細胞 / 腫瘍壊死因子 / アディポネクチン Less
  • Research Projects

    (4 results)
  • Research Products

    (49 results)
  • Co-Researchers

    (7 People)
  •  Regulation of anti-arteriosclerotic activity between anti-oxidative enzyme and adipocytokines

    • Principal Investigator
      ADACHI Tetsuo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Gifu Pharmaceutical University
  •  Inhibition of cell proliferation in glomeruli using overexpression of anti-oxidative enzymePrincipal Investigator

    • Principal Investigator
      YAMADA Harutaka
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Aichi Medical University, School of Medicine
  •  Mesangial cell regulation under the over expression of oxygen radical scavengersPrincipal Investigator

    • Principal Investigator
      YAMADA Harutaka
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Aichi Medical University
  •  Application of endothelial cell-binding superoxide dismutase (EC-SOD) on screening of the initiation-progress of renal diseases

    • Principal Investigator
      ADACHI Tetsuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Gifu Pharmaceutical university

All 2009 2008 2007 2006 2005 2004 2002 2001 2000 1999 1997 1996

All Journal Article Presentation Book

  • [Book] 低酸素状態下でのCOS-7細胞におけるextracellularsuperoxide dismutaseの発現(腎とフリーラジカル第9集)2008

    • Author(s)
      足立哲夫, 山田晴生, 神谷哲朗, 登石泰介, 原宏和, 今井裕一
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 腎とフリーラジカル 第9集-22008

    • Author(s)
      山田晴生ら
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 腎とフリーラジカル 第9集-32008

    • Author(s)
      山田晴生ら
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 培養平滑筋細胞のextracellular-superoxide dismutase産生(腎とフリーラジカル第9集)2008

    • Author(s)
      山田晴生, 山田裕一, 足立哲夫, 宮本敢右, 木村行宏, 鹿島悠佳理, 竹沢有美子, 前田邦博, 水野奈津子, 青山龍平, 森由貴, 若松亮, 山口諭, 菅憲弘, 渡辺一司, 北川 渡, 三浦直人, 西川和裕, 普天間新生, 今井裕一
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 腹腔内extracellularsuperoxide dismutase産生誘導(腎とフリーラジカル第9集)2008

    • Author(s)
      山田晴生, 足立哲夫, 山田裕一, 宮本敢右, 木村行宏, 鹿島悠佳理, 竹沢有美子, 前田邦博, 水野奈津子, 青山龍平, 森由貴, 若松亮, 山口諭, 菅憲弘, 渡辺一司, 北川渡, 三浦直人, 西川和裕, 普天間新生, 今井裕一
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 別冊・医学のあゆみ.酸化ストレスver.2 -フリーラジカル医学生物学の最前線-2006

    • Author(s)
      山田晴生 ら
    • Total Pages
      4
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 細胞外型Cu, Zn-SODと慢性腎不全. 別冊・医学のあゆみ. 酸化ストレスver. 2-フリーラジカル医学生物学の最前線-2006

    • Author(s)
      山田晴生, 足立哲夫, 山田裕一, 今井裕一
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] CAPD療法での腹腔内extracellular superoxide dismutase産生(腎とフリーラジカル第8集)2006

    • Author(s)
      山田晴生, 山田裕一, 足立哲夫, 吉野雅文, 渡邊一司, 北川 渡, 西川和裕, 普天間新生, 今井裕一
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 腎とフリーラジカル 第8集-12006

    • Author(s)
      山田晴生 ら
    • Total Pages
      5
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 腎とフリーラジカル 第8集-22006

    • Author(s)
      山田晴生 ら
    • Total Pages
      4
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Book] 血液透析患者の血清抗malondialdehyde-modified LDL(MDA-LDL)抗体とその意義(腎とフリーラジカル第8集)2006

    • Author(s)
      山田晴生, 足立哲夫, 山田裕一, 森由貴, 青山龍平, 三浦直人, 佐久間正人, 西川和裕, 普天間新生, 今井裕一
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Journal Article] Cobalt chloride decreases EC-SOD expression through intracellular ROS generation and p38-MAPK pathways in COS7 cells2008

    • Author(s)
      Kamiya T, Hara H, Yamada H, Imai H, Inagaki N, Adachi T
    • Journal Title

      Free Rad. Res 42

      Pages: 949-956

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Journal Article] Acute renal failure due to IgM-lambda glomerular thrombi and MPGN-like lesions in a patient with angioimmunoblastic T-Cell lymphoma.2006

    • Author(s)
      Yamada H 他
    • Journal Title

      Am J Kidney Dis. 48

      Pages: 3-9

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Activation of hypoxia-inducible factor 1 during macrophage differentiation.2006

    • Author(s)
      Yamada H 他
    • Journal Title

      Am J Physiol Cell Physiol. 291

      Pages: 104-113

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] 血液透析患者の血清抗malondialdehyde-modified LDL (MDA-LDL)抗体とその意義2006

    • Author(s)
      山田晴生他
    • Journal Title

      腎とフリーラジカル第8集 8

      Pages: 136-139

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] CAPD療法での腹腔内extracellular-supexide dismutase産生2006

    • Author(s)
      山田晴生他
    • Journal Title

      腎とフリーラジカル第8集 8

      Pages: 125-129

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] 酸化ストレスと老化・疾患 腎疾患 細胞外型Cu,Zn-superoxide dismutaseと慢性腎不全2006

    • Author(s)
      山田晴生他
    • Journal Title

      医学のあゆみ・別冊酸化ストレスVer.2 10

      Pages: 326-329

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Acute renal failure due to IgM-lambda glomerular thrombi and MPGN-like lesions in a patient with angioimmunoblastic T-Cell lymphoma.2006

    • Author(s)
      Miura N, Suzuki K, Yoshino M, Kitagawa W, Yamada H, Ohtani H, Joh K, Imai H.
    • Journal Title

      Am J Kidney Dis. 48(1)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] 血液透析患者の血清抗malondialdehyde-modified LDL(MDA-LDL)抗体とその意義2006

    • Author(s)
      山田晴生他
    • Journal Title

      腎とフリーラジカル第8集 8

      Pages: 136-139

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] CAPD療法での腹腔内extracelluIar-superoxidedismutase産生2006

    • Author(s)
      山田晴生他
    • Journal Title

      腎とフリーラジカル第8集 8

      Pages: 125-129

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Extracellular-superoxide dismutase production in mesangial cell growing inextracellular matrix2005

    • Author(s)
      Yamada H, Adachi T, Yamada Y, Misao S, Suzuki K, Watanabe H, Kitagawa W, Miura N, You C, Sakuma M, Nishikawa K, Futenma A, Imai H.
    • Journal Title

      Nippon Jinzo Gakkai Shi. Japanese. 47(1)

      Pages: 32-37

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] 培養メサンギウム細胞の産生 Extra cellular Superoxlde Dismutase(EC-SOD)と細胞外基質2005

    • Author(s)
      山田晴生, 足立哲夫, 山田裕一, 三竿幸子, 鈴木啓介, 渡辺一司, 北川渡, 三浦直人, 楊朝隆, 佐久間正人, 西川和裕, 普天間新生, 今井裕一
    • Journal Title

      日本腎臓学会誌 47

      Pages: 32-37

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] The increase of antiglomerular basement membrane antibody following pauci-immune-type crescentic glomerulonephritis2005

    • Author(s)
      Wataru Kitagawa, Naoto Miura, Harutaka Yamada, Kazuhiro Nishikawa, Arao Futenma, Hirokazu Imai
    • Journal Title

      Clin Exp Nephrol 9

      Pages: 69-73

    • NAID

      10015563646

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] The increase of antiglomerular basement membrane antibody following pauci-immune-type crescentic glomerulonephritis.2005

    • Author(s)
      Yamada H 他
    • Journal Title

      Clin Exp Nephrol. 9

      Pages: 69-73

    • NAID

      10015563646

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] The increase of antiglomerular basement membrane antibody following pauci-immune-type crescentic glomerulonephritis.2005

    • Author(s)
      Kitagawa W, Miura N, Yamada H, Nishikawa K, Futenma A, Imai H.
    • Journal Title

      Clin Exp Nephrol. 9(1)

      Pages: 69-73

    • NAID

      10015563646

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] The increase of anti-glomerular basement membrane antibody following pauci-immune-type crescentic glomerulonephritis2005

    • Author(s)
      Harutaka Yamada
    • Journal Title

      Clinical and experimental nephrology 9

      Pages: 13-19

    • NAID

      10015563646

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Establishment of anti-rat-Cu,Zn-superoxide dismutase monoclonal antibodies applied to a highly sensitive immunoassay and immunohistochemistry system.2004

    • Author(s)
      Yamada H 他
    • Journal Title

      Hybrid Hybridomics. 23・4

      Pages: 232-236

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Mesangial cell extracellular-superoxide dismutase production under the cell grow and extracellular matrix.2004

    • Author(s)
      Yamada H, Adachi T, Yamada Y, Misao S, Kitagawa W, Nomura T, Aoki T, Miura N, Sakuma M, Nishikawa K, Futenma A, Imai H.
    • Journal Title

      Nephrology (Carlton). 9 Suppl 2

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] HUS/TTP2004

    • Author(s)
      山田晴生
    • Journal Title

      腎臓ナビゲーター 6

      Pages: 144-145

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] プレドニゾロンによるメサンギウム細胞産生Extracellular-superoxide dismutase産生2004

    • Author(s)
      山田晴生
    • Journal Title

      腎とフリーラジカル 第7集 7

      Pages: 26-29

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] In vitroでの骨芽細胞・破骨細胞の再現と活性酸素・消去系の関与2004

    • Author(s)
      山田晴生
    • Journal Title

      腎とフリーラジカル 第7集 7

      Pages: 112-115

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Mesangial cell extracellular-superoxide dismutase production under the cell grow and extracellular matrix.2004

    • Author(s)
      Harutaka Yamada
    • Journal Title

      Nephrology 9

      Pages: 53-54

    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Extracellular superoxide dismutase and glomerular mesangial cells : its production and regulation.2002

    • Author(s)
      Yamada H, Adachi T, Fukatsu A, Misao S, Yamada Y, Aoki T, Miura N, Sakuma M, Nishikawa K, Futenma A, Kakumu S.
    • Journal Title

      FEBS Lett. 519(1-3)

      Pages: 77-81

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Heparin-stimulated expression of extracellular-superoxide dismutase in human fibroblasts.2001

    • Author(s)
      Adachi T, Hara H, Yamada H, Yamazaki N, Yamamoto M, Sugiyama T, Futenma A, Katagiri Y.
    • Journal Title

      Atherosclerosis. 159(2)

      Pages: 307-12

    • NAID

      110000054687

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Protective role of extracellular superoxide dismutase in hemodialysis patients.2000

    • Author(s)
      Yamada H, Yamada Y, Adachi T, Fukatsu A, Sakuma M, Futenma A, Kakumu S.
    • Journal Title

      Nephron. 84(3)

      Pages: 218-23

    • NAID

      110000054570

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Increase of urinary extracellular-superoxide dismutase level correlated with cyclic adenosine monophosphate.1999

    • Author(s)
      Adachi T, Yamada H, Hara H, Futenma A, Kakumu S.
    • Journal Title

      FEBS Lett. 458(3)

      Pages: 370-4

    • NAID

      110000054417

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Polymorphism of extracellular superoxide dismutase (EC-SOD) gene : relation to the mutation responsible for high EC-SOD level in serum.1997

    • Author(s)
      Yamada H, Yamada Y, Adachi T, Goto H, Ogasawara N, Futenma A, Kitano M, Miyai H, Fukatsu A, Hirano K, Kakumu S.
    • Journal Title

      Jpn J Hum Genet. 42(2)

      Pages: 353-6

    • NAID

      10013839445

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] An arginine-213 to glycine mutation in human extracellular-superoxide dismutase reduces susceptibility to trypsin-like proteinases.1996

    • Author(s)
      Adachi T, Morihara N, Yamazaki N, Yamada H, Futenma A, Kato K, Hirano K.
    • Journal Title

      J Biochem (Tokyo). 120(1)

      Pages: 184-8

    • NAID

      10005188386

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Journal Article] Substitution of glycine for arginine-213 in extracellular-superoxide dismutase impairs affinity for heparin and endothelial cell surface.1996

    • Author(s)
      Adachi T, Yamada H, Yamada Y, Morihara N, Yamazaki N, Murakami T, Futenma A, Kato K, Hirano K.
    • Journal Title

      Biochem J. 1;313(Pt 1)

      Pages: 235-9

    • NAID

      110000053912

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590865
  • [Presentation] 低酸素状態下のCOS7細胞におけるextracellular-superoxidedismutase発現調節2009

    • Author(s)
      神谷哲朗, 原宏和, 山田晴生, 今井裕一, 稲垣直樹, 足立哲夫
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] in vitro低酸素誘導時のCOS7細胞におけるEC-SODの発現2008

    • Author(s)
      神谷哲朗, 原宏和, 山田晴生, 今井裕一, 足立哲夫
    • Organizer
      第61回日本酸化ストレス学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] Extracellular superoxide dismutase production from dialysis fluid in peritomeal dialysis and culture fibroblast under tochoferol exposure2007

    • Author(s)
      Yamada H, Adachi T, Yamada Y, Kimura Y, Miyamoto K, Aoyama R, Kashima Y, Takezawa Y, Maeda K, Mizuno N, Yoshino M, Wakamatsu R, Mori Y, Yamaguchi S, Suga N, Watanabe H, Kitagawa W, Miura N, Nishikawa K, Futenm A, Imai H
    • Organizer
      The 3rd Asian Chapter Meeting of International Society for Peritoneal Dialysis
    • Place of Presentation
      Hiroshima
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] 培養平滑筋細胞・メサンギウム細胞のExtracellularsuperoxi dedismutase産生2007

    • Author(s)
      山田晴生, 足立哲夫, 山田裕一, 宮本敢右, 木村行宏, 鹿島悠佳理, 竹澤有美子, 前田邦博, 水野奈津子, 森由貴, 青山龍平, 吉野雅人, 若松亮, 山口諭, 管憲広, 渡辺一司, 北川渡, 三浦直人, 西川和裕, 普天間新生, 今井裕一
    • Organizer
      第19回腎とフリーラジカル研究会
    • Place of Presentation
      浜松
    • Year and Date
      2007-09-29
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] The expression of extracelular superoxide dismutase in COS7 cells during hypoxia2007

    • Author(s)
      Adachi T, Yamada H, Kamiya T, Toishi T, Hara H, Imai H
    • Organizer
      14th Annual meeting of Society for Free Radical Biology and Medicine
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] 低酸素状態下でのCOS-7細胞におけるsuperoxide dismutaseの発現の変動2007

    • Author(s)
      足立哲夫, 山田晴生, 原宏和, 今井裕一
    • Organizer
      日本薬学会第127年会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] Extracellular superoxide dismutase production from dialysis fluid in peritomeal dialysis and culture fibroblast under tochoferol exposure2007

    • Author(s)
      Harutaka Yamada, et. al.
    • Organizer
      The 3rd Asian Chapter Meeting of International Society for Peritoneal Dialysis
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] 培養平滑筋細胞・メサンギウム細胞のExtracellular-superoxide dismutase産生2007

    • Author(s)
      山田晴生, ら
    • Organizer
      第19回腎とフリーラジカル研究会
    • Place of Presentation
      浜松
    • Year and Date
      2007-09-29
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] 腹腔内extracellular-superoxide dismutase産生の誘導2006

    • Author(s)
      山田晴生, 足立哲夫, 山田裕一, 尾関教生, 山口諭, 管憲広, 鈴木啓介, 渡辺一司, 北川渡, 三浦直人, 佐久間正人, 西川和裕, 普天間新生, 今井裕一
    • Organizer
      第18回腎とフリーラジカル研究会
    • Place of Presentation
      筑波
    • Year and Date
      2006-09-23
    • Data Source
      KAKENHI-PROJECT-18590146
  • [Presentation] 低酸素状態下でのCOS-7細胞におけるextracellularsuperoxide dismutaseの発現2006

    • Author(s)
      足立哲夫, 山田晴生, 登石泰介, 甲田明英, 原宏和, 今井裕一
    • Organizer
      第18回腎とフリーラジカル研究会
    • Place of Presentation
      筑波
    • Year and Date
      2006-09-23
    • Data Source
      KAKENHI-PROJECT-18590146
  • 1.  ADACHI Tetsuo (40137063)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 15 results
  • 2.  HARA Hirokazu (30305495)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 3.  FUTENMA Arao (80173508)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 4.  KAMIYA Tetsuro (60453057)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  SAKUMA Masato (90257684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NISHIKAWA Kazuhiro (30301625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 7.  宮井 宏暢 (70190733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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