Kondo Kazuhiro 近藤一博

… Alternative Names

KONDO Kazuhiro 近藤一博

近藤一博コンドウカズヒロ

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Researcher Number	70234929
Other IDs
External Links
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 東京慈恵会医科大学, 医学部, 教授 2015 – 2017: 東京慈恵会医科大学, 医学部, 教授 2010: 東京慈恵会医科大学, 医学部, 教授 2009: 東京慈惠会医科大学, 医学部, 教授 2003 – 2008: The Jikei University School of Medicine, Professor, 医学部, 教授 … More 1999 – 2002: 大阪大学, 医学系研究科, 助教授 1998: Osaka University Medical School, Associate Professor, 医学部, 助教授 1995 – 1998: 大阪大学, 医学部, 助教授 1992: 大阪大学, 微生物病研究所, 助手 Less
Review Section/Research Field	Principal Investigator Virology / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Virology / Environmental physiology(including physical medicine and nutritional physiology) Except Principal Investigator Virology / Biological Sciences / Virology / Pediatrics
Keywords	Principal Investigator HHV-6 / ヒトヘルペスウイルス6 / 潜伏感染 / 再活性化 / ストレス / human herpesvirus 6 / reactivation / latency / HHV-7 / 疲労 … More / SITH-1 / うつ病 / マクロファージ / ヒトヘルペスウイルス7 / cytomegalovirus / サイトメガロウイルス / Heterogeneous Ribonucleoprotein K / Casein Kinase 2 / 潜伏感染遺伝子 / human herpesvirus 7 / mRNA / ヘルペスウイルス / 潰瘍性大腸炎 / ストレスレジリエンス / コリン作動性抗炎症経路 / ドネペジル / 脳内炎症 / アセチルコリン / レジリエンス / 脳疲労 / 血液検査 / 炎症性サイトカイン / 肝臓 / 睡眠不足 / バイオマーカー / 運動負荷 / 病的疲労 / 生理的疲労 / 精神疲労 / 身体疲労 / fatigue / stress / SCID-hu mouse / SCID-huマウス / immediate early gene / latency-associated transcript / 中枢神経系 / Heterogeneous Ribonucleprotein K / 前初期遺伝子 / Exanthem Subitum / macrophage / 突発性発疹 / 神経膠細胞 / NASBA / AIDS / 臓器移植 / 骨髄移植 / NASBA法 / 潜状感染 / 疲労因子 / 病原性 / 中枢神経 … More Except Principal Investigator HHV-6 / HCMV / HHV-7 / 潜伏感染 / latency / 前初期遺伝子 / reactivation / ヒトヘルペスウイルス6 / 再活性化 / KSHV / latency-associated transcript / human herpesvirus 6 / cytomegalovirus / 潜伏感染遺伝子 / サイトメガロウイルス / Reactivation / Immediate-early gene / Latency / IE2 / IE1 / IE 1 / Glycoprotein / Herpesvirus / immediate early / PCR / 初期タンパク / シークエンス / DNA / モノクローン抗体 / クローニング / US22family / 前初期タンパク / Yeactivation / glycoprotein / Harposvirus / inunediat early / ロタウイルス脳炎・脳症 / 単純ヘルペス / 炎症性サイトカイン / DNAマイクロアレイ / チトクロームC / ロタウイルス / 新型インフルエンザ / インフルエンザ脳症 / 酸化ストレス / チオレドキシン(TRX) / インフルエンザ / ロタウィルス / サイトカイン / 急性脳炎 / 小児感染症学 / 急性脳症 / HHV-8 / カポジ肉腫関連ヘルペスウイルス / ヒトヘルペスウイルス8 / クラスI遺伝子 / K5 / メチル化 / RTA / γヘルペスウイルス / HHV8 Less

前脳基底部のアセチルコリン産生をハブとした新規ストレス応答経路の同定と機能解析Principal Investigator
- Principal Investigator
  
  近藤一博
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Jikei University School of Medicine
Elucidation of the effect of HHV-6 SITH-1, a risk factor for depression, on stress resiliencePrincipal Investigator
- Principal Investigator
  
  Kondo Kazuhiro
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Jikei University School of Medicine
Elucidation of the mechanism of occurrence and recovery of brain fatigue for the purpose of reducing the risk of depressionPrincipal Investigator
- Principal Investigator
  
  Kondo Kazuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Jikei University School of Medicine
Development of fatigue measurement method using herpes virus which can distinguish between mental fatigue and physical fatiguePrincipal Investigator
- Principal Investigator
  
  Kondo Kazuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Jikei University School of Medicine
Study on the pathogenesis of acute encephalitis and encephalopathy for the effective treatment and prevention
- Principal Investigator
  
  MORISHIMA Tsuneo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Okayama University
Fatigue and be-ta herpesvirus reactivationPrincipal Investigator
- Principal Investigator
  
  KONDO Kazuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Jikei University School of Medicine
Visualization and analysis of human herpesvirus 6 and 7 using their recombinant virusesPrincipal Investigator
- Principal Investigator
  
  KONDO Kazuhiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Jikei University
Development of novel methods for diagnosis of cytomegalovirus and HHV-6 reactivation.
- Principal Investigator
  
  YAMANISHI Koichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University
ヘルペスウイルスの潜伏感染・再活性化の機構解析
- Principal Investigator
  
  山西弘一
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Analysis of human herpesvirus 6 latent infection in the brain.Principal Investigator
- Principal Investigator
  
  KONDO Kazuhiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The Jikei University School of Medicine
  Osaka University
ヘルペスウイルスの潜伏感染・再活性化の機構解析
- Principal Investigator
  
  YAMANISHI Koichi
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Molecular mechanism of human herpesvirus 6 latent infectionPrincipal Investigator
- Principal Investigator
  
  KONDO Kazuhiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Osaka University
Monitoring method of human cytomegalovirus latent infection and viral reactivationPrincipal Investigator
- Principal Investigator
  
  KONDO Kazuhiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University
Molecular mechanism of human herpesvirus 6 latent infectorPrincipal Investigator
- Principal Investigator
  
  KONDO Kazuhiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Osaka University
ヒトヘルペスウイルス6の潜伏感染とその中枢神経系細胞に与える影響に関する研究Principal Investigator
- Principal Investigator
  
  近藤一博
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Osaka University
Mechanism of latent infection of human herpesvirus 6
- Principal Investigator
  
  YAMANISHI Koichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University
Study on pathogenesis of Human herpesvirus 6 and 7 infection
- Principal Investigator
  
  YAMANISHI Koichi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  Osaka University

[Book] Chronic Fatigue Syndrome and Herpesvirus Infection. In : Fatigue Science for Human Health2008
- Author(s)
  K. Kondo
- Publisher
  Springer Press
- Data Source
  KAKENHI-PROJECT-19590483
[Book] Fatigue Science for Human Health2008
- Author(s)
  K. Kondo
- Publisher
  Springer Press
- Data Source
  KAKENHI-PROJECT-19590483
[Book] HHV-6A, 6B, and 7 : molecular basis of latency and reactivation. In : Ann Arvin et.al. editors2007
- Author(s)
  K. Kondo and Yamanishi K.
- Publisher
  Human Herpesviruses. Cambridge University Press
- Data Source
  KAKENHI-PROJECT-19590483
[Book] Human Herpesviruses.2007
- Author(s)
  K. Kondo
- Publisher
  Cambridge University Press
- Data Source
  KAKENHI-PROJECT-19590483
[Journal Article] Donepezil for Fatigue and Psychological Symptoms in Post-COVID-19 Condition: A Randomized Clinical Trial.2025
- Author(s)
  Nakamura K, Kondo K, Oka N, Yamakawa K, Ie K, Goto T, Fujitani S.
- Journal Title
  
  JAMA Netw Open
  
  Volume: 8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24596
[Journal Article] Donepezil for Fatigue and Psychological Symptoms in Post-COVID-19 Condition: A Randomized Clinical Trial.2025
- Author(s)
  Nakamura K, Kondo K, Oka N, Yamakawa K, Ie K, Goto T, Fujitani S.
- Journal Title
  
  JAMA Netw Open
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24596
[Journal Article] Efficacy of Donepezil for Fatigue and Psychological Symptoms in Post-COVID-19 Condition: Study Protocol for a Multicenter Randomized, Placebo-controlled, Double-blind Trial2024
- Author(s)
  Kawabata K, Nakamura K, Kondo K, Oka N, Ishii A, Idei M, Yamakawa K, Ie K, Yamamoto Y, Nishi K, Hirahata K, Kikuchi R, Yoshida H, Saito H, Goto T, Fujitani S.
- Journal Title
  
  Annals of Clinical Epidemiology
  
  Volume: 6 Issue: 4 Pages: 87-96
- DOI
  10.37737/ace.24013
- ISSN
  2434-4338
- URL
  https://marianna-u.repo.nii.ac.jp/records/2000916
- Year and Date
  2024-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24596
[Journal Article] Suppressors of Cytokine Signaling Are Decreased in Major Depressive Disorder Patients2022
- Author(s)
  Kobayashi Nobuyuki、Shinagawa Shunichiro、Nagata Tomoyuki、Shigeta Masahiro、Kondo Kazuhiro
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 12 Issue: 7 Pages: 1040-1040
- DOI
  10.3390/jpm12071040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07553, KAKENHI-PROJECT-23K24596
[Journal Article] 特集ウイルス感染症に強くなる!-予防･診断･治療のポイント《総論》ウイルスの基礎知識-形態,感染様式などについて2022
- Author(s)
  小林伸行、近藤一博
- Journal Title
  
  耳鼻咽喉科・頭頸部外科
  
  Volume: 94 Issue: 8 Pages: 606-610
- DOI
  10.11477/mf.1411203083
- ISSN
  0914-3491, 1882-1316
- Year and Date
  2022-07-20
- Data Source
  KAKENHI-PROJECT-21K07553, KAKENHI-PROJECT-23K24596
[Journal Article] VP26, a herpes simplex virus type 1 capsid protein, increases DNA methylation in COASY promoter region2022
- Author(s)
  Osaka Rui、Kobayashi Nobuyuki、Shimada Kazuya、Ishii Azusa、Oka Naomi、Kondo Kazuhiro
- Journal Title
  
  Brain, Behavior, & Immunity - Health
  
  Volume: 26 Pages: 100545-100545
- DOI
  10.1016/j.bbih.2022.100545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07553, KAKENHI-PROJECT-23K24596
[Journal Article] Blood DNA Methylation Levels in the WNT5A Gene Promoter Region: A Potential Biomarker for Agitation in Subjects with Dementia2021
- Author(s)
  Kobayashi Nobuyuki、Shinagawa Shunichiro、Nagata Tomoyuki、Tagai Kenji、Shimada Kazuya、Ishii Azusa、Oka Naomi、Shigeta Masahiro、Kondo Kazuhiro
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 81(4) Issue: 4 Pages: 1601-11
- DOI
  10.3233/jad-210078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03891, KAKENHI-PROJECT-21K07553
[Journal Article] Cooperative activation of the human herpesvirus 6B U79/80 early gene promoter by immediate‐early proteins IE1B and IE2B2020
- Author(s)
  Shimada Kazuya、Kobayashi Nobuyuki、Oka Naomi、Takahashi Mayumi、Kondo Kazuhiro
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 64 Issue: 11 Pages: 747-761
- DOI
  10.1111/1348-0421.12844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08354, KAKENHI-PROJECT-19H03891
[Journal Article] Human Herpesvirus 6B Greatly Increases Risk of Depression by Activating Hypothalamic-Pituitary -Adrenal Axis during Latent Phase of Infection2020
- Author(s)
  Kobayashi Nobuyuki、Oka Naomi、Takahashi Mayumi、Shimada Kazuya、Ishii Azusa、Tatebayashi Yoshitaka、Shigeta Masahiro、Yanagisawa Hiroyuki、Kondo Kazuhiro
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 6 Pages: 101187-101187
- DOI
  10.1016/j.isci.2020.101187
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03891
[Journal Article] Attenuation of human herpesvirus 6B reactivation by aging2019
- Author(s)
  Kobayashi Nobuyuki、Nishiyama Toshiko、Yamauchi Takashi、Shimada Kazuya、Suka Machi、Kondo Kazuhiro、Yanagisawa Hiroyuki
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 91 Issue: 7 Pages: 1335-1341
- DOI
  10.1002/jmv.25434
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03891, KAKENHI-PROJECT-17K10318
[Journal Article] Increased interleukin-1β and basic fibroblast growth factor levels in the cerebrospinal fluid during human herpesvirus-6B (HHV-6B) encephalitis2017
- Author(s)
  Tamai Masato、Kobayashi Nobuyuki、Shimada Kazuya、Oka Naomi、Takahashi Mayumi、Tanuma Akiko、Tanemoto Tomohiro、Namba Hiroyuki、Saito Yoshihiro、Wada Yasuyuki、Okamoto Aikou、Ida Hiroyuki、Kondo Kazuhiro
- Journal Title
  
  Biochemical and biophysical research communications
  
  Volume: 486 Issue: 3 Pages: 706-711
- DOI
  10.1016/j.bbrc.2017.03.102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10318, KAKENHI-PROJECT-15K08216, KAKENHI-PROJECT-26860946
[Journal Article] Caregiver burden and fatigue in caregivers of people with dementia: Measuring human herpesvirus (HHV)-6 and & -7 DNA levels in saliva,2016
- Author(s)
  Tohmi Osaki, Takako Morikawa, Hiroyuki Kajita, Nobuyuki Kobayashi, Kazuhiro Kondo, Kiyoshi Maeda.
- Journal Title
  
  Archives of Gerontology and Geriatrics
  
  Volume: 66 Pages: 42-48
- DOI
  10.1016/j.archger.2016.04.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461758, KAKENHI-PROJECT-15K08216, KAKENHI-PROJECT-26860946
[Journal Article] Usefulness of DNA Methylation Levels in COASY and SPINT1 Gene Promoter Regions as Biomarkers inDiagnosis of Alzheimer's Disease and Amnestic Mild Cognitive Impairment.2016
- Author(s)
  Kobayashi N, Shinagawa S, Nagata T, Shimada K, Shibata N, Ohnuma T, Kasanuki K, Arai H, Yamada H, Nakayama K, Kondo K.
- Journal Title
  
  PloS one
  
  Volume: 11 Issue: 12 Pages: e0168816-e0168816
- DOI
  10.1371/journal.pone.0168816
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08216, KAKENHI-PROJECT-26860946
[Journal Article] DNA methylation in the NCAPH2/LMF2 promoter region is associated with hippocampal atrophy in Alzheimer's disease and amnesic mild cognitive impairment patients.2016
- Author(s)
  Shinagawa S, Kobayashi N, Nagata T, Kusaka A, Yamada H, Kondo K, Nakayama K.
- Journal Title
  
  Neurosci Lett
  
  Volume: 629 Pages: 33-37
- DOI
  10.1016/j.neulet.2016.06.055
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08216, KAKENHI-PROJECT-26860946
[Journal Article] Human herpesvirus 6 and 7 are biomarkers for fatigue, which distinguish between physiological fatigue and pathological fatigue.2016
- Author(s)
  Aoki, R., Kobayashi, N., Suzuki, G., Kuratsune, H., Shimada, K., Oka, N., Takahashi, M., Yamadera, W., Iwashita, M., Tokuno, S., Nibuya, M., Tanichi, M., Mukai, Y., Mitani, K., Kondo, K., Ito, H., Nakayama, K.
- Journal Title
  
  Biochem. Biophy. Res. Commun.
  
  Volume: 478 Issue: 1 Pages: 424-430
- DOI
  10.1016/j.bbrc.2016.07.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02502, KAKENHI-PROJECT-15K08216, KAKENHI-PROJECT-15K09816, KAKENHI-PROJECT-26860946
[Journal Article] Development of Biomarkers Based on DNA Methylation in the NCAPH2/LMF2 Promoter Region for Diagnosis of Alzheimer’s Disease and Amnesic Mild Cognitive Impairment．2016
- Author(s)
  Nobuyuki Kobayashi, Shunichiro Shinagawa, Tomoyuki Nagata, Kazuya Shimada, Nobuto Shibata, Tohru Ohnuma, Koji Kasanuki, Heii Arai, Hisashi Yamada, Kazuhiko Nakayama, Kazuhiro Kondo.
- Journal Title
  
  PLoS ONE
  
  Volume: 11(1) Issue: 1 Pages: e0146449-e0146449
- DOI
  10.1371/journal.pone.0146449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08216, KAKENHI-PROJECT-26860946
[Journal Article] 疲労の尺度と疾病2015
- Author(s)
  小林伸行, 近藤一博
- Journal Title
  
  臨床透析
  
  Volume: 5(1) Pages: 64-73
- Data Source
  KAKENHI-PROJECT-15K08216
[Journal Article] Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer's Disease.2015
- Author(s)
  Nagata T, Kobayashi N, Ishii J, Shinagawa S, Nakayama R, Shibata N, Kuerban B, Ohnuma T, Kondo K, Arai H, Yamada H, Nakayama K.
- Journal Title
  
  Dementia and geriatric cognitive disorders extra
  
  Volume: 5(1) Pages: 64-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08216
[Journal Article] Effects of nutritional supplementation on fatigue, and autonomic and immune dysfunction in patients with end-stage renal disease: a randomized, double-blind, placebo-controlled, multicenter trial2015
- Author(s)
  F ukuda S, Koyama H, Kondo K, Fujii H, Hirayama Y, Tabata T, Okamura M, Yamakawa T, Okada S, Hirata S, Kiyama H, Kajimoto O, Watanabe Y, Inaba M, Nishizawa Y
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 3 Pages: e0119578-e0119578
- DOI
  10.1371/journal.pone.0119578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461371, KAKENHI-PROJECT-15K08216
[Journal Article] Subacute encephalopathy : Clinical features, laboratory data, neuroimaging, and outcomes.2008
- Author(s)
  Okumura A, Kidokoro H, Itomi K, Maruyama K, Kubota T, Kondo Y, Itomi S, Uemura N, Natsume J, Watanabe K, Morishima T.
- Journal Title
  
  Pediatr Neurol 38
  
  Pages: 111-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249053
[Journal Article] Subacute encephalopathy : clinical features, laboratory data, neuroimaging, and outcomes.2008
- Author(s)
  Okumura A. Kidokuro H. Itomi K. Maruyama K, Kubota T, Kondo Y. Itomi S. Uemura S, Satsume J, Watanabe K, Morishima T.
- Journal Title
  
  Pediatr Neurol. 38(2)
  
  Pages: 111-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249053
[Journal Article] Human herpesvirus 6 (HHV-6) transmits from parent to child by integration form and characterization of cases with chromosomally integrated HHV-6 DNA.2004
- Author(s)
  K.Tanaka-Taya, Sashihara J, Kurahashi H, Amo K, Miyagawa H, Kondo K, Okada S, Yamanishi K.
- Journal Title
  
  Journal of Medical Virology 73(3)
  
  Pages: 465-473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390149
[Journal Article] Productive human herpesvirus 6 infection causes aberrant accumulation of p53 and prevents apoptosis.2004
- Author(s)
  Takemoto M, Mori Y, Ueda K, Kondo K, Yamanishi K.
- Journal Title
  
  Journal of General Virology 85(4)
  
  Pages: 869-879
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390149
[Journal Article] Novel Strage of Beta-Herpesvirus Latency in Human Herpesvirus 6.2003
- Author(s)
  K.Kondo et al.
- Journal Title
  
  J.Virol. 77(3)
  
  Pages: 2258-2264
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390149
[Journal Article] Detection of a gene cluster that is dispensable for human herpesvirus 6 replication and latency.2003
- Author(s)
  K.Kondo, Nozaki H, Shimada K, Yamanishi K.
- Journal Title
  
  Journal of Virology 77(19)
  
  Pages: 10719-10724
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390149
[Journal Article] Human herpesvirus 6 immediate-early 2 protein interacts with heterogeneous ribonucleoprotein k and casein kinase 2.2003
- Author(s)
  Shimada K, Kondo K, Yamanishi K.
- Journal Title
  
  Microbiology and Immunology 48(3)
  
  Pages: 205-210
- NAID
  10012684513
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390149
[Journal Article] Detection of agene cluster that is dispensable for human herpesvirus 6 replication and latency.2003
- Author(s)
  K.Kondo et al.
- Journal Title
  
  J.Virol. 77(19)
  
  Pages: 10719-10724
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390149
[Journal Article] Recognition of a novel stage of beta-herpesvirus latency in human herpesvirus 6.
- Author(s)
  K.Kondo, Sashihara J, Shimada K, Amo K, Miyagawa H, Takemoto M, Yamanishi K.
- Journal Title
  
  Journal of Virology 77(3)
  
  Pages: 2258-2264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390149
[Patent] HHV-6潜伏感染に関連する気分障害を治療又は予防する方法2008
- Inventor(s)
  近藤一博小林伸行
- Industrial Property Rights Holder
  近藤一博(株)ウイルス医科学研究所
- Filing Date
  2008-10-03
- Overseas
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] 新型コロナウイルス感染症（COVID-19）後遺症のトランスレーショナルリサーチ―COVID-19後遺症精神症状に対するドネペジルの第II相臨床試験の成果―2024
- Author(s)
  岡直美，石井梓，嶋田和也，中村謙介，藤谷茂樹，家研也，山川一馬，平畑光一，近藤一博
- Organizer
  第71回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24596
[Presentation] 新型コロナウイルス感染症（COVID-19）後遺症のトランスレーショナルリサーチ―COVID-19後遺症精神症状に対するドネペジルの第II相臨床試験の成果2024
- Author(s)
  岡直美，石井梓，嶋田和也，中村謙介，藤谷茂樹，家研也，山川一馬，平畑光一，近藤一博
- Organizer
  第71回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24596
[Presentation] 嗅球に潜伏感染したヒトヘルペスウイルス６による脳内炎症の誘導2022
- Author(s)
  岡直美, 小林伸行, 嶋田和也, 石井梓, 近藤一博
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24596
[Presentation] 単純ヘルペスウイルス1型カプシドタンパクVP26によるCOASY プロモーター領域のDNAメチル化亢進2022
- Author(s)
  小林伸行, 小坂瑠衣, 嶋田和也, 石井梓, 岡直美, 近藤一博
- Organizer
  第69回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-23K24596
[Presentation] 新型コロナウイルス感染症 (COVID-19)後遺症モデルマウスの作製および病態の解析2022
- Author(s)
  岡直美, 小林伸行, 石井梓, 近藤一博
- Organizer
  第18回日本疲労学会
- Data Source
  KAKENHI-PROJECT-23K24596
[Presentation] 新型コロナウイルス感染症（COVID-19）後遺症モデルマウスにおける脳内炎症発生メカニズムの解明2022
- Author(s)
  岡直美, 嶋田和也, 石井梓, 小林伸行, 近藤一博.
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-23K24596
[Presentation] ORF152は先天性CMV感染症において神経病原性を誘導する2022
- Author(s)
  嶋田和也, 小林伸行, 岡直美, 石井梓, 近藤一博
- Organizer
  第69回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-23K24596
[Presentation] 特別講演3　ヒトヘルペスウイルス6(HHV-6)が潜伏感染状態で引き起こす疾患　―うつ病ウイルス原因説―2021
- Author(s)
  近藤一博
- Organizer
  第72回日本皮膚科学会中部支部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] うつ病の発症における潜伏感染ヒトヘルペスウイルス６の役割2021
- Author(s)
  岡直美，小林伸行，石井梓，近藤一博
- Organizer
  第17回日本疲労学会
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] 教育講演30 うつ病の原因遺伝子の発見 ―ヒトヘルペスウイルス６(HHV-6) SITH-1によるうつ病発症―2021
- Author(s)
  近藤一博
- Organizer
  第117回日本精神神経学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] 労働疲労の科学ーうつ病の克服を目指してー2020
- Author(s)
  近藤一博
- Organizer
  第16回日本疲労学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] 身体疲労回復機能を持つ食品成分のスクリーニング2020
- Author(s)
  岡直美、小林伸行、近藤一博
- Organizer
  第16回日本疲労学会
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] 大うつ病における血液中炎症性サイトカイン抑制因子の影響2020
- Author(s)
  小林伸行、岡直美、近藤一博
- Organizer
  第16回日本疲労学会
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] イミダゾールジペプチドが疲労の発生および疲労回復に与える影響の解析2019
- Author(s)
  岡直美, 小林伸行, 近藤一博
- Organizer
  第15回日本疲労学会
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] 一般労働者における時間外労働時間の増加による唾液中ヒトヘルペスウイルス(HHV-)6及びHHV-7 DNA量の低下2019
- Author(s)
  小林伸行、西山寿子、岡直美、近藤一博
- Organizer
  第15回日本疲労学会
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] Attenuation of human herpesvirus (HHV-) 6B and HHV-7 reactivation by aging.2019
- Author(s)
  Kobayashi, N., Shimada, K., Nishiyama, T., Yamauchi, T., Suka, M., Yanagisawa, H., Kondo, K.
- Organizer
  The 66th Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-19H03891
[Presentation] 唾液中に分泌されたHHV-6がうつ病を発症させるメカニズムの解明2017
- Author(s)
  岡直美、小林伸行、髙橋麻弓、嶋田和也、近藤一博
- Organizer
  第13回日本疲労学会
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] 分子機構から明らかにする疲労とストレスとの相違に関する検討.2017
- Author(s)
  小林伸行, 岡直美, 髙橋麻弓, 玉井将人, 嶋田和也, 近藤一博.
- Organizer
  第13回日本疲労学会
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] 疲労によって誘導されるウイルス因子が関与するうつ病発症メカニズムの解明2017
- Author(s)
  岡直美、小林伸行、嶋田和也、髙橋麻弓、近藤一博
- Organizer
  第39回生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] 疲労によって誘導されるウイルス因子が関与するうつ病発症メカニズムの解明2016
- Author(s)
  岡直美、小林伸行、嶋田和也、髙橋麻弓、近藤一博
- Organizer
  第38回生物学的精神医学会
- Place of Presentation
  福岡
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] 唾液中ヒトヘルペスウイルス(HHV-)6及びHHV-7量による病的疲労と生理的疲労との鑑別に関する検討2016
- Author(s)
  小林伸行, 青木亮, 岡直美, 髙橋麻弓 , 嶋田和也, 玉井将人, 山寺亘, 岩下正幸, 倉恒弘彦, 伊藤洋, 中山和彦, 近藤一博
- Organizer
  第12回日本疲労学会
- Place of Presentation
  横浜
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] 唾液中に分泌されたHHV-6がうつ病を発症させるメカニズムの解明2016
- Author(s)
  岡直美、小林伸行、嶋田和也、髙橋麻弓、近藤一博
- Organizer
  第12回日本疲労学会
- Place of Presentation
  横浜
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] Human herpesvirus 6 (HHV-) and HHV-7 reactivation in fatigue, which distinguishes between physiological fatigue and pathological fatigue.2016
- Author(s)
  Kobayashi, R.Aoki, H. Kuratsune, N. Oka, M.Takahashi, K. Shimada, W. Yamadera, M. Iwashita, H. Ito, K. Nakayama, K. Kondo.
- Organizer
  The 64th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  Sapporo
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] Human Cytomegalovirus (HCMV) Latency-Associated Protein ORF152 Induces Calcium Influx and Inhibits Gene Expression in Central Nervous System2015
- Author(s)
  Kazuya Shimada, Nobuyuki Kobayashi, Naomi Oka, Masato Tamai, Kazuhiro Kondo.
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] 睡眠時無呼吸症候群を対象とした、HHV-6、HHV-7の再活性化メカニズムの検討2015
- Author(s)
  小林伸行, 青木亮, 嶋田和也, 玉井将人, 山寺亘, 岩下正幸, 伊藤洋, 中山和彦, 近藤一博
- Organizer
  第63回日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] HCMV潜伏感染タンパク質ORF152が神経機能に与える影響2015
- Author(s)
  嶋田和也、小林伸行、岡直美、玉井将人、近藤一博
- Organizer
  第29回ヘルペスウイルス研究会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-15K08216
[Presentation] Brain Science on Fatigue, Identification of a novel HHV-6 latent-protein associated with CFS and mood disorders. K.Kondo2010
- Author(s)
  K.Kondo
- Organizer
  Neuro 2010
- Place of Presentation
  Kobe(Symposium)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20249053
[Presentation] ヒトヘルペスウイルス6(HHV-6)の細胞特異性とスプライシング関連因子SART3の発現量に関する解析2010
- Author(s)
  嶋田和也、近藤一博
- Organizer
  第58回日本ウイルス学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20249053
[Presentation] Identification of a novel molecular mechanism and a major cause of fatigue.2009
- Author(s)
  Kondo N.
- Organizer
  36th International Congress of Physiological Sciences. Late-breaking symposium
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20249053
[Presentation] スプライシング関連因子SART3のアンチセンスによるヒトヘルペスウイルス6(HHV-6) ie1/ie2 mRNAの選択的スプライシングに対する影響2008
- Author(s)
  嶋田和也、近藤一博
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] スプライシング関連因子SART3のアンチセンスによるヒトヘルペスウイルス6(HHV-6)ie1/ie2 mRNAの選択的スプライシングに対する影響2008
- Author(s)
  嶋田和也, 近藤一博
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] Identification of novel HHV-6 latent protein associated with mood disorders in CFS, depressive disorder, bipolar disorder and HHV-6 encephalopathy2008
- Author(s)
  K. Kondo, N. Kobayashi, K. Shimada, H. Kuratsune, H. Matsunaga
- Organizer
  International Symposium on Viruses in Chronic Fatigue Syndrome
- Place of Presentation
  Baltimore
- Year and Date
  2008-06-22
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] 遺伝子治療を目的としたヒトヘルペスウイルス6ベクターの性状解析2008
- Author(s)
  清水昭宏、小林伸行、近藤一博
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] ヒトヘルペスウイルス(HHV)-6潜伏感染中間状態特異的タンパクによる気分障害の発症機序2008
- Author(s)
  小林伸行、嶋田和也、清水昭宏、近藤一博
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] Identification of novel HHV-6 latent protein associated with mood disorders in CFS, depressive disorder, bipolar disorder and HHV-6 encephalopathy.2008
- Author(s)
  K. Kondo
- Organizer
  International Symposium on Viruses in Chronic Fatigue Syndrome
- Place of Presentation
  Baltimore
- Year and Date
  2008-06-22
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] HHV-6感染SCID-huマウスを用いたHHV-6潜伏感染細胞の同定2008
- Author(s)
  鎌田美乃里、近藤一博
- Organizer
  第56回日本ウイルス学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] Enhancement of herpes virus 6 (HHV-6) and herpesvirus 7 (HHV-7) reactivation in saliva during the fatigue state2007
- Author(s)
  T.Sugino, Y.Kajimoto, H. Kuratsune, Y. Watanabe, K. Kondo
- Organizer
  International Association of Chronic Fatigue Syndrome
- Place of Presentation
  Fort Lauderdale
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] ヒトヘルペスウイルス6(HHV-6)の細胞指向性に関与するウイルス遺伝子の同定と解析2007
- Author(s)
  清水昭宏、小林伸行、近藤一博
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] HHV-6 潜伏感染特異的タンパクによるうつ症状の発症機序2007
- Author(s)
  小林伸行, 清水昭宏, 近藤一博, 他
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] HHV-6の細胞指向性に関与するウイルス遺伝子の同定と解析2007
- Author(s)
  清水昭宏, 小林伸行, 近藤一博
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] β-ヘルペスウイルスのストレス応答による再活性化機構の解明2007
- Author(s)
  近藤一博、清水昭宏、小林伸行
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] HHV-6感染SCID-huマウスを用いたHHV-6潜伏感染細胞の同定2007
- Author(s)
  鎌田美乃里、近藤一博
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] ヒトヘルペスウイルス(HHV)-6潜伏感染特異的タンパクによるうつ症状の発症機序2007
- Author(s)
  小林伸行、嶋田和也、清水昭宏、近藤一博
- Organizer
  第55回日本ウイルス学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] 疲労のバイオマーカーとしてのヘルペスウイルス再活性化2006
- Author(s)
  近藤一博
- Organizer
  第2回日本疲労学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] HHV-6感染SCID-huマウスにおけるHHV-6感染様式の解析2006
- Author(s)
  鎌田美乃里、近藤一博
- Organizer
  第54回日本ウイルス学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] ヒトヘルペスウイルス7(HHV-7)の細胞指向性関連遺伝子領域の同定と機能解析2006
- Author(s)
  清水昭宏、近藤一博
- Organizer
  第54回日本ウイルス学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] ヒトヘルペスウイルス(HHV)-6とHHV-7の再活性化の誘導因子としての疲労2006
- Author(s)
  近藤一博、鎌田美乃里、小林伸行
- Organizer
  第54回日本ウイルス学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590483
[Presentation] ヒトヘルペスウイルス6(HHV-6)初期遺伝子制御機構の解析-初期遺伝子プロモーター間の比較検討-2006
- Author(s)
  嶋田和也、武本眞清、山西弘一、近藤一博
- Organizer
  第54回日本ウイルス学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590483

1. YAMANISHI Koichi (10029811)

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# of Collaborated Products: 5 results
2. TAYA Keiko (80263276)

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3. INAGI Reiko (50232509)

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4. KURATA Takeshi (50012779)

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5. ISEGAWA Yuji (20184583)

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6. 上田啓次 (00221797)

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7. 岡直美 (00704503)

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8. MORISHIMA Tsuneo (90157892)

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9. OKABE Nobuhiko (10057028)

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10. NAKAGOMI Osamu (70143047)

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11. NUNOI Hiroyuki (50218260)

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12. HOSOYA Mitsuaki (80192318)

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13. MATSUKAWA Akihiro (90264283)

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14. KIMURA Hioroshi (30303621)

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15. YOSHIKAWA Tetsushi (80288472)

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16. ICHIYAMA Takashi (20263767)

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17. OKUMURA Akihisa (60303624)

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18. SHIMAMOTO Takuya (00281121)

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19. 森康子 (50343257)

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20. 高橋和郎 (10171472)

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22. AONO Toshiya

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23. MAEDA Kiyoshi

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24. KAJITA Hiroyuki

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25. KOBAYASHI Nobuyuki

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26. KOYAMA Hidenori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 品川俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 嶋田和也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 倉恒弘彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kondo Kazuhiro 近藤 一博

KONDO Kazuhiro 近藤 一博

近藤 一博 コンドウ カズヒロ

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前脳基底部のアセチルコリン産生をハブとした新規ストレス応答経路の同定と機能解析Principal Investigator

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Elucidation of the effect of HHV-6 SITH-1, a risk factor for depression, on stress resiliencePrincipal Investigator

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Elucidation of the mechanism of occurrence and recovery of brain fatigue for the purpose of reducing the risk of depressionPrincipal Investigator

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Development of fatigue measurement method using herpes virus which can distinguish between mental fatigue and physical fatiguePrincipal Investigator

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Study on the pathogenesis of acute encephalitis and encephalopathy for the effective treatment and prevention

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Fatigue and be-ta herpesvirus reactivationPrincipal Investigator

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Visualization and analysis of human herpesvirus 6 and 7 using their recombinant virusesPrincipal Investigator

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Development of novel methods for diagnosis of cytomegalovirus and HHV-6 reactivation.

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ヘルペスウイルスの潜伏感染・再活性化の機構解析

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Analysis of human herpesvirus 6 latent infection in the brain.Principal Investigator

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ヘルペスウイルスの潜伏感染・再活性化の機構解析

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Molecular mechanism of human herpesvirus 6 latent infectionPrincipal Investigator

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Monitoring method of human cytomegalovirus latent infection and viral reactivationPrincipal Investigator

Principal Investigator

Kondo Kazuhiro 近藤一博

KONDO Kazuhiro 近藤一博

近藤一博コンドウカズヒロ

[Journal Article] 特集ウイルス感染症に強くなる!-予防･診断･治療のポイント《総論》ウイルスの基礎知識-形態,感染様式などについて2022