Yamada Shuhei 山田修平

… Alternative Names

Researcher Number	70240017
Other IDs
External Links
Affiliation (Current)	2019: 名城大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2019: 名城大学, 薬学部, 教授 2013: 北海道大学, 大学院・先端生命科学研究院, 准教授 2007 – 2011: Hokkaido University, Faculty of Advanced Life Science, Associate Professor 2006: Hokkaido Univ., Faculty of Advanced Life Science, Associate Professor., 大学院先端生命科学研究院, 助教授 2000 – 2005: Dept.of Biochemistry, KOBE PHARMACEUTICAL UNIVERSITY Lecturer, 薬学部, 講師 … More
Review Section/Research Field	Principal Investigator Biological pharmacy / 医薬分子機能学 / Biological pharmacy / Biological Sciences / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Biological pharmacy / Biological pharmacy / Structural biochemistry / 医薬分子機能学 / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 48040:Medical biochemistry-related / 生物系薬学
Keywords	Principal Investigator ヘパラン硫酸 / コンドロイチン硫酸 / 硫酸化オリゴ糖 / ヘパリン / 硫酸化グリコサミノグリカン / グリコサミノグリカン / ^1H NMR / ヒアルロン酸 / ヒアルロニダーゼ / プロテオグリカン … More Except Principal Investigator コンドロイチン硫酸 / デルマタン硫酸 / ヘパラン硫酸 / プロテオグリカン / グリコサミノグリカン / ヘパリン / chondroitin sulfate / 硫酸化オリゴ糖 / 硫酸化 / 糖転移酵素 / 神経突起 / 神経突起伸長 / 増殖因子 / 硫酸基転移酵素 / プレイオトロフィン / 脳 / イズロン酸 / 肝細胞増殖因子 / シンデカン / EXT / glycosaminoglycan / heparan sulfate / neurite outgrowth / dermatan sulfate / ヘパリナーゼ / コンドロイチナーゼ / 細胞増殖因子 / フォリスタチン / ミッドカイン / 2-アミノベンズアミド / MS / アピカン / 遺伝病 / 癌 / RAGE / 硫酸化グリコサミノグリカン / Sulfation / NMR / 癌抑制遺伝子 / グルクロン酸転移酵素 / glycosyltransferase / 線虫 / ガン抑制遺伝子 / RNAi / sulfotransferase / chondroitin polymerizing factor / 糖尿病 / ヘパリチナーゼ / スルファターゼ / フオリスタチン / コンドロチチナーゼ / 神系突起 / 蛍光標識 / NALDI-TOF / プロトンNMR / リン酸化 / perineuronal net / cMet / 計算科学 / デルマタン硫酸エピメラーゼ / 単クローン抗体 / 加水分解酵素 / basic FGF / 肝再生 / 計科学 / 転移 / ルイス肺癌細胞 / プロテオミクス / オリゴ糖 / コンドロイチン硫酸/デルマタン硫酸/骨 / 皮膚/遺伝病/脊椎骨端異形成症/ エーラス / ダンロス症候群/糖転移酵素/硫酸基転移酵素 / 骨形成 / 変形性関節症 / ドイツ / ニュージーランド / ガラクトース硫酸 / Heparin / Chondroitin sulfate / Glycosaminoglycans / Galactose / インター-α-トリプシンインヒビター / ウリナリートリプシンインヒビタ / GalNAc転移酵素 / インターα-トリプシンインヒビター / ウリマリ-トリプシンインヒビター / ESI / Glycosaminoglycan / Dermatan Sulfate / Chondroitin Sulfate / Sulfated Oligosaccharides / EXT遺伝子ファミリー / 血管新生 / コンドロイチン硫酸E / アンジオモジュリン / N-アセチルグルコサミン / コンドロイチン / ヘバラン硫酸 / tumor suppressor / EXT gene family / angiogenesis / コンドロイチナーゼC / マンノサミン / C2-エピメリゼーション / デルマタン流酸 / 螢光標識 / heparin / heparin sulfate / sulfated oligosaccharides / heparinase / chondroitinase / ヘパリン結合性増殖因子 / ヘパラナーゼ / 癌転移 / EXT癌抑制遺伝子 / アミロイド前駆体タンパク質 / X線結晶構造解析 / エンド-beta-グルクロニダーゼ / ラミニン / グルコサミン-3硫酸 / 遺伝子構造 / heparin-binding growth factors / heparanase / tumor metastasis / EXT tumor suppressor genes / glycosyltransferases / amyloid precursor protein / コンドロイチン合成酵素 / コンドロイチン重合因子 / 糖転位酵素 / グルクロン酸転位酵素 / ショウジョウバエ / N-アセチルガラクトサミン転移酵素 / chondroitin synthase / 硫酸基転位酵素 / 先天性脊髄・骨端異形成症 / コンドロイチン重合化因子 / RNA Interference / RNA / 先天性脊椎・骨端異形成症 / RANi / プライオトロフィン / spondyloepiphysial dysplasia / RNA intereference / pleiotrpohin / ヒドラ / 糖鎖 / 小脳 / 神経細胞 / herpes simplex virus / iduronic acid / hydra / carbohydrate chain / hepatocyte growth factor / pleiotrophin / アルツハイマー病 / 骨・皮膚疾患 / 老化 / てんかん / 筋拘縮型エーラス・ダンロス症候群 / iPS細胞 / マウスモデル / 包括的病態解析 / インスリン分泌 / シンデカン４ / ヘパラン硫酸プロテオグリカン / 膵β細胞 / Golgin / GORAB / エーラス・ダンロス症候群 / 脊椎骨端骨幹端異形成症 / 骨異形成性老人性皮膚症 / 免疫不全症 / LFNG / 結合組織疾患 / 脊椎肋骨異骨症 / 骨系統疾患 / 皮膚弛緩症 / ゴルジン / ゴルジ体 / 遺伝性骨・皮膚疾患 Less

Integrated understanding of dermatan sulfate through uncovering pathophysiology of musculocontractural Ehlers-Danlos syndromeOngoing
- Principal Investigator
  
  古庄知己
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Shinshu University
Elucidation of the novel functions of EXTL3 involved in the biosynthesis of heparan sulfate in brains and T cellsPrincipal InvestigatorOngoing
- Principal Investigator
  
  山田修平
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Meijo University
シンデカン４ノックアウトマウスにおけるインスリン分泌機能の解析Ongoing
- Principal Investigator
  
  高橋巌
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Iwate Medical University
Mechanism of biosynthesis of glycosaminoglycan by Golgin, and its hereditary bone and skin disorders
- Principal Investigator
  
  Mizumoto Shuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物系薬学
- Research Institution
  Meijo University
Function as well as regulation on expression of a novel hyaluronidase in cancer and inflammationPrincipal Investigator
- Principal Investigator
  
  Yamada Shuhei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
脳におけるコンドロイチン硫酸およびヒアルロン酸の代謝分解機構の解明Principal Investigator
- Principal Investigator
  
  山田修平
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Meijo University
Roles of chondroitin sulfate interacting with RAGE involved in tumor and Alzheimer's disease
- Principal Investigator
  
  Shiji Mizumoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
Structural and functional studies on the novel hyaluronidase trying for its clinical applicationPrincipal Investigator
- Principal Investigator
  
  YAMADA Shuhei
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meijo University
Molecular mechanism for roles of chondroitin sulfate in tumor metastasis
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Pathogenic mechanisms of the bone diseases caused by defect in chondroitin sulfate biosynthesis
- Principal Investigator
  
  MIZUMOTO Shuji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Identification of endo-type chondroitin sulfate hydrolases applicable to neuronal regenerative therapyPrincipal Investigator
- Principal Investigator
  
  YAMADA Shuhei
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Molecular mechanism of proteoglycan signalings
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Study on the structure and functions of sulfated glycosaminoglycans involved in the development or treatment of liver diseases.Principal Investigator
- Principal Investigator
  
  YAMADA Shuhei
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Functional analysis of glycosaminoglycans as a potential drug target and the decoding of carbohydrate signaling of the functional domains
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
胎児脳のグリコサミノグリカンによる神経幹細胞の分化と神経突起伸長の分子メカニズム
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
  Kobe Pharmaceutical University
Changes in the specificity of the interaction between cell growth/differentiation factors and glycosaminoglycans during development and differentiation.Principal Investigator
- Principal Investigator
  
  YAMADA Shuhei
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
  Kobe Pharmaceutical University
Development of a fundamental technology, which is applicable to drug development and therapeutic applications through analysis of sulfated glycosaminoglycan chains
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KOBE PHARMACEUTICAL UNIVERSITY
コンドロイチン/デルマタン硫酸の神経突起伸長促進機能とその分子メカニズム
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
ヘパラン硫酸(HS)生合成酵素である癌抑制遺伝子EXT1欠損マウスのHSの解析Principal Investigator
- Principal Investigator
  
  山田修平
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
癌の浸潤・転移に関与するヘパラナーゼ及び血管新生調節因子アンジオモジュリンの研究Principal Investigator
- Principal Investigator
  
  山田修平
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kobe Pharmaceutical University
Analysis of the biosynthetic mechanism and functions of glycosaminogycans by manipulating the genes encoding biosynthetic enzymes.
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
Development of the haparan sulfate-based anti-cancer drugs
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KOBE PHARMACEUTICAL UNIVERSITY
発生や分化に伴うヘパラン硫酸の微細構造と増殖・分化因子との結合能の変動と相関Principal Investigator
- Principal Investigator
  
  山田修平
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kobe Pharmaceutical University
パートタイムプロテオグリカンへの糖鎖付加の分子スイッチの同定とその機能調節の解明
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
癌性細胞接着因子の活性発現調節因子であるヘパリン、ヘパラン硫酸の構造と機能の解析Principal Investigator
- Principal Investigator
  
  山田修平
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kobe Pharmaceutical University
神経突起伸長と血管新生におけるグリコサミノグリカン糖鎖の分子認識
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biological pharmacy
- Research Institution
  KOBE PHARMACEUTICAL UNIVERSITY
Development of a universal sequencing method for sulfated glycosaminoglycans
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kobe Pharmaceutical University
ヘパリン/ヘパラン硫酸の微細硫酸化構造と細胞増殖・分化因子の調節活性との相関Principal Investigator
- Principal Investigator
  
  山田修平
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kobe Pharmaceutical University
細胞の増殖・分化促進活性を有する硫酸化グリコサミノグリカン糖鎖の分子認識
- Principal Investigator
  
  菅原一幸
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Kobe Pharmaceutical University
血中及び尿中のトリプシンインヒビターに結合した新奇コンドロイチン硫酸の構造解析Principal Investigator
- Principal Investigator
  
  山田修平
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
ヘパリナーゼ、ヘパリチナーゼの基質特異性の研究Principal Investigator
- Principal Investigator
  
  山田修平
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Pharmaceutical University
Structure and Biosynthesis of Carbohydrate-Protein Linkage Region of Dermatan Sulfate and Chondroitin Sulfate
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kobe Pharmaceutical University
グリコサミノグリカン多糖鎖のリン酸化と硫酸化による精密硫酸化構造の意義に関する研究
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kobe Pharmaceutical University
Structural Study on th Carbohydrate-Protein Linkage Region of Proteglycans
- Principal Investigator
  
  SUGAHARA Kazuyuki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe Women's College of Pharmacy

[Book] 糖鎖の新機能開発　応用ハンドブック - 創薬　医療から食品開発まで2015
- Author(s)
  山田修平、水本秀二、菅原一幸
- Total Pages
  628
- Publisher
  エヌ　ティー　エス
- Data Source
  KAKENHI-PUBLICLY-26110719
[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada
- Total Pages
  2500
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Chondroitin Sulfate In Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Shuhei Yamada
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24590071
[Book] Biochemical Roles of Eukaryotic Cell Surface Macromolecules2015
- Author(s)
  Shuhei Yamada
- Total Pages
  411
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-24590071
[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
- Total Pages
  2672
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-26110719
[Book] Encyclopedia of Polymeric Nanomaterials2015
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, and Shuhei Yamada
- Total Pages
  2672
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K07951
[Book] Biochemical Roles of Eukaryotic Cell Surface Macromolecules2015
- Author(s)
  Shuhei Yamada
- Total Pages
  411
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-26110719
[Book] グリコサミノグリカン・プロテオグリカンの分解 In 糖鎖の新機能開発・応用ハンドブック～創薬・医療からヘルスケアまで～2015
- Author(s)
  山田修平、水本秀二、菅原一幸
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-25860037
[Book] Adv. Exp. Med. Biol. Vol 749, “Biochemical Roles of Eukaryotic Cell Surface Macromolecules” (Sudhakaran, P. and Surolia, A., eds.)2012
- Author(s)
  Shuhei Yamada
- Total Pages
  340
- Publisher
  Springer, Heidelberg
- Data Source
  KAKENHI-PROJECT-24590071
[Book] 遺伝子医学MOOK別冊ますます重要になる細胞周辺環境(細胞ニッチ)の最新科学技術 .細胞の生存、増殖、機能のコントロールから創薬研究、再生医療まで.2009
- Author(s)
  水本秀二,山田修平,菅原一幸
- Total Pages
  230
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21590057
[Book] Experimental Glycoscience "Glycochemistry"(Taniguchi N., Suzuki A., Ito Y., Narimatsu H., Kawasaki T., Hase S., eds) (Microsequencing of functional chondroitin sulfate oligosaccharides)2008
- Author(s)
  Sugahara K., Yamada S.
- Publisher
  Springer, Tokyo
- Data Source
  KAKENHI-PROJECT-20390019
[Book] Springer, Tokyo2008
- Author(s)
  Kazuyuki Sugahara and Shuhei Yamada
- Publisher
  Experimental Glycoscience Glycochemistry,
- Data Source
  KAKENHI-PROJECT-19590052
[Book] タンパク質の翻訳後修飾解析プロトコール2006
- Author(s)
  山田修平
- Total Pages
  287
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590078
[Book] グリコサミノグリカン糖鎖の構造解析法2006
- Author(s)
  山田修平
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Book] タンパク質の翻訳後修飾解析プロトコール2005
- Author(s)
  山田修平
- Total Pages
  9
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17590078
[Book] タンパク質の翻訳後修飾解析プロトコール2005
- Author(s)
  山田修平
- Total Pages
  286
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390026
[Journal Article] Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with mcEDS-CHST142019
- Author(s)
  Takuya Hirose, Naoki Takahashi, Prasarn Tangkawattana, Jun Minaguchi, Shuji Mizumoto, Shuhei Yamada, Noriko Miyake, Shujiro Hayashi, Atsushi Hatamochi, Jun Nakayama, Tomomi Yamaguchi, Ayana Hashimoto, Yoshihiro Nomura, Kazushige Takehana, Tomoki Kosho, and Takafumi Watanabe
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1863 Pages: 623-631
- DOI
  10.1016/j.bbagen.2018.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Identification of novel LFNG mutations in spondylocostal dysostosis2019
- Author(s)
  Otomo N, Mizumoto S, Lu HF, Takeda K, Campos-Xavier B, Mittaz-Crettol L, Guo L, Takikawa K, Nakamura M, Yamada S, Matsumoto M, Watanabe K, Ikegawa S.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: - Pages: 261-264
- DOI
  10.1038/s10038-018-0548-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10986, KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K16709
[Journal Article] Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus.2018
- Author(s)
  Yusuke Mii, Takayoshi Yamamoto, Ritsuko Takada, Shuji Mizumoto, Makoto Matsuyama, Shuhei Yamada, Shinji Takada, and Masanori Taira
- Journal Title
  
  Nat. Commun.
  
  Volume: 8 Pages: 1973-1973
- DOI
  10.1038/s41467-017-02076-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K19418, KAKENHI-PLANNED-24111002, KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-17H05782
[Journal Article] Defect in dermatan sulfate in urine of patients with Ehlers-Danlos syndrome caused by a CHST14/D4ST1 deficiency.2018
- Author(s)
  Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  Clin. Biochem.
  
  Volume: 50 Pages: 670-677
- DOI
  10.1016/j.clinbiochem.2017.02.018
- NAID
  120006398760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-15K07951
[Journal Article] Identification of biallelic EXTL3 mutations in a novel type of spondylo-epi-metaphyseal dysplasia.2018
- Author(s)
  *Long Guo, *Nursel H Elcioglu, *Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shiro Ikegawa (equal contribution)
- Journal Title
  
  J. Hum. Genet.
  
  Volume: － Pages: 797-801
- DOI
  10.1038/jhg.2017.38
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-17K16710, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H05357, KAKENHI-PROJECT-15K07951
[Journal Article] The reduction of heparan sulphate in the glomerular basement membrane does not augment urinary albumin excretion.2018
- Author(s)
  Satoshi Aoki, Akiko Saito-Hakoda, Takeo Yoshikawa, Kyoko Shimizu, Kiyomi Kisu, Susumu Suzuki, Kiyoshi Takagi, Shuji Mizumoto, Shuhei Yamada, Toin H. van Kuppevelt, Atsushi Yokoyama, Taiji Matsusaka, Hiroshi Sato, Sadayoshi Ito, and Akira Sugawara
- Journal Title
  
  Nephrol. Dial. Transplant.
  
  Volume: 33 Pages: 26-33
- DOI
  10.1093/ndt/gfx218
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-16K08606, KAKENHI-PROJECT-16K08645, KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-15K09420, KAKENHI-PROJECT-16K15492, KAKENHI-PROJECT-16H03252
[Journal Article] Vascular abnormalities in the placenta of Chst14-/- fetuses: implications in the pathophysiology of perinatal lethality of the murine model and vascular lesions in human CHST14/D4ST1 deficiency.2018
- Author(s)
  Takahiro Yoshizawa, Shuji Mizumoto, Yuki Takahashi, Shin Shimada, Kazuyuki Sugahara, Jun Nakayama, Shin’ichi Takeda, Yoshihiro Nomura, Yuko Nitahara-Kasahara, Takashi Okada, Kiyoshi Matsumoto, Shuhei Yamada, and Tomoki Kosho
- Journal Title
  
  Glycobiology
  
  Volume: 28 Pages: 80-89
- DOI
  10.1093/glycob/cwx099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08251, KAKENHI-PROJECT-16K19396, KAKENHI-PROJECT-15K07951
[Journal Article] Screening of known disease genes in congenital scoliosis2018
- Author(s)
  Takeda K, Kou I, Mizumoto S, Yamada S, Kawakami N, Nakajima M, Otomo N, Ogura Y, Miyake N, Matsumoto N, Kotani T, Sudo H, Yonezawa I, Uno K, Taneichi H, Watanabe K, Shigematsu H, Sugawara R, Taniguchi Y, Minami S, Nakamura M, Matsumoto M; Japan Early Onset Scoliosis Research Group, Watanabe K, Ikegawa S.
- Journal Title
  
  Mol Genet Genomic Med.
  
  Volume: - Pages: 966-974
- DOI
  10.1002/mgg3.466
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10986, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16K08251
[Journal Article] Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) deficiency results in a mild skeletal dysplasia and joint laxity2017
- Author(s)
  Julia Vodopiutz, Shuji Mizumoto, Ekkehard Lausch, Antonio Rossi, Sheila Unger, Nikolaus Janocha, Rainer Seidl, Susanne Greber-Platzer, Shuhei Yamada, Thomas Muller, Bernd Jilma, Rudolf Ganger, Andrea Superti-Furga, Shiro Ikegawa, Kazuyuki Sugahara, Andreas R. Janecke.
- Journal Title
  
  Human Mutation
  
  Volume: 38 Pages: 34-38
- DOI
  10.1002/humu.23070
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-16K08251
[Journal Article] Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders2017
- Author(s)
  Shuji Mizumoto, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Pharmaceuticals
  
  Volume: 10
- DOI
  10.3390/ph10020034
- NAID
  120006335578
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Functional validation of novel compound heterozygous variants in B3GAT3 resulting in severe osteopenia and fractures: expanding the disease phenotype2016
- Author(s)
  *Florian Job, *Shuji Mizumoto, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saal, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, Shuhei Yamada, Katrin Hoffmann, Kazuyuki Sugahara, Emily Farrow. (*equal contribution)
- Journal Title
  
  BMC Medical Genetics
  
  Volume: 17 Pages: 86-86
- DOI
  10.1186/s12881-016-0344-9
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PROJECT-16K08251
[Journal Article] Molecular interactions between chondroitin-dermatan sulfate and growth factors/receptors/matrix proteins.2016
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 34 Pages: 35-42
- DOI
  10.1016/j.sbi.2015.06.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Structural analysis of chondroitin and dermatan sulfate in Receptor for Advanced Glycation End-products (RAGE) knockout mice2016
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Bulletin of Research Institute of Meijo University
  
  Volume: 21 Pages: 209-212
- NAID
  40020904531
- Data Source
  KAKENHI-PROJECT-16K08251
[Journal Article] Catabolism of Chondroitin Sulfate2015
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Cellular and Molecular Biology Letters
  
  Volume: 20
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26110719
[Journal Article] Mutations in biosynthetic enzymes for the protein linker region of chondroitin/dermatan/heparan sulfate cause skeletal and skin dysplasias.2015
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  BioMed Research International
  
  Volume: 2015 Pages: 861752-861752
- DOI
  10.1155/2015/861752
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07951, KAKENHI-PUBLICLY-26110719, KAKENHI-PROJECT-25860037
[Journal Article] Catabolism of Chondroitin Sulfate2015
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Cell. Mol. Biol. Lett.
  
  Volume: 20 Pages: 196-2212
- DOI
  10.1515/cmble-2015-0011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590071
[Journal Article] Human Genetic Disorders and Knockout Mice Deficient in Glycosaminoglycan2014
- Author(s)
  Shuji Mizumoto, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  BioMed Research International
  
  Volume: 2014 Pages: 495764-495764
- DOI
  10.1155/2014/495764
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590071, KAKENHI-PROJECT-25860037, KAKENHI-PUBLICLY-26110719
[Journal Article] Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis2013
- Author(s)
  Shuji Mizumoto, Moto Watanabe, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  BioMed Research International
  
  Volume: 2013 Pages: 656319-656319
- NAID
  120005906914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Expression of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase involved in chondroitin sulfate synthesis is responsible for pulmonary metastasis2013
- Author(s)
  Mizumoto, S., Watanabe, M., Yamada, S., and Sugahara, K.
- Journal Title
  
  BioMed Research International
  
  Volume: 2013 Pages: 656319-656319
- DOI
  10.1155/2013/656319
- NAID
  120005906914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Mass preparation of oligosaccharides by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system2013
- Author(s)
  Shuhei Yamada, Keiichiro Matsushima, Haruo Ura, Nobuyuki Miyamoto, Kazuyuki Sugahara
- Journal Title
  
  Carbohydr. Res.
  
  Volume: 371 Pages: 16-21
- DOI
  10.1016/j.carres.2013.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24110501, KAKENHI-PROJECT-24590071
[Journal Article] Highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences with bioctivities2013
- Author(s)
  Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  Glycobiology
  
  Volume: 23 Pages: 155-168
- DOI
  10.1093/glycob/cws137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790066, KAKENHI-PUBLICLY-24110501
[Journal Article] Specific interaction of the envelope glycoproteins E1 and E2 with liver heparin sulfate involved in the tissue tropismatic infection by hepatitis C virus2012
- Author(s)
  Kobayashi, F., Yamada, S., Taguwa, S., Naito, S., Tani, H., Matsuura, Y., and Sugahara, K.
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 29 Pages: 211-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-24790451
[Journal Article] Identification of amino acid residues required for the substrate specificity of human and mouse chondroitin sulfate hydrolase (conventional hyaluronidase-4)2012
- Author(s)
  Tomoyuki Kaneiwa, Anzu Miyazaki, Ryo Kogawa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Pages: 42119-42128
- DOI
  10.1074/jbc.m112.360693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590071
[Journal Article] Specific interaction of the envelope glycoproteins E1 and E2 with liver heparan sulfate involved in the tissue tropismatic infection by hepatitis C virus2012
- Author(s)
  Fumi Kobayashi, Shuhei Yamada, Shuhei Taguwa, Chikako Kataoka, Satomi Naito, Yoshiki Hama, Hideki Tani, Yoshiharu Matsuura, Kazuyuki Sugahara
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 29(4) Pages: 211-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] 新規のコンドロイチン硫酸に特異的な加水分解酵素2012
- Author(s)
  山田修平
- Journal Title
  
  応用糖質科学
  
  Volume: 2 Pages: 104-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590071
[Journal Article] 新規のコンドロイチン硫酸に特異的な加水分解酵素2012
- Author(s)
  山田修平
- Journal Title
  
  応用糖質科学
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Hyaluronidases have strong hydrolytic activity toward chondroitin 4-sulfate comparable to that for hyaluronan2012
- Author(s)
  Tomoko Honda, Tomoyuki Kaneiwa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada
- Journal Title
  
  Biomolecules
  
  Volume: 2 Pages: 549-563
- DOI
  10.3390/biom2040549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590071
[Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011
- Author(s)
  Jiancheng Chen, Shuhei Yamada#, Yoshiki Hama, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Naonori Takahashi, Kazuya I. P. J. Hidari, Takashi Suzuki, Yasuo Suzuki, and Kazuyuki Sugahara#
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 412(1) Pages: 136-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in α-Thrombomodulin from Human Urine2011
- Author(s)
  Taishi Hashiguchi, Shuji Mizumoto, Yuko Nishimura, Jun-ichi Tamura, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286(38) Pages: 33003-33011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Demonstration of the hepatocyte growth factor signaling pathway in the in vitro neuritogenic activity of chondroitin sulfate from ray fish cartilage2011
- Author(s)
  Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Biochimica et Biophysica Acta (General Subjects)
  
  Volume: 1810(4) Pages: 406-413
- NAID
  120002934270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain.2011
- Author(s)
  Akatsu C., Mizumoto S., Kaneiwa T., Maccarana M., Malmstrom A., Yamada S., Sugahara K.
- Journal Title
  
  Glycobiology 21(5)
  
  Pages: 565-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage.2011
- Author(s)
  Hashiguchi Y., Kobayashi T., Fongmoon D., Shetty A.K., Mizumoto S., Miyamoto N., Nakamura T., Yamada S., Sugahara K.
- Journal Title
  
  Biochim.Biophys.Acta 1810(4)
  
  Pages: 406-413
- NAID
  120002934270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Involvement of HNK-1 sulfotransferase in the biosynthesis of the GlcUA(3-O-sulfate)-Gal-Gal-Xyl tetrasaccharide found in ?-thrombomodulin from human urine2011
- Author(s)
  Taishi Hashiguchi, Shuji Mizumoto, Yuko Nishimura, Jun-ichi Tamura, Shuhei Yamada#, and Kazuyuki Sugahara#
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286(38) Pages: 33003-33011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Evolution of Glycosaminoglycans : Comparative Biochemical Study.2011
- Author(s)
  Yamada S., Sugahara K., Ozbek S.
- Journal Title
  
  Commun.Integr.Biol. (in press.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Evolution of Glycosaminoglycans: Comparative Biochemical Study2011
- Author(s)
  Shuhei Yamada#, Kazuyuki Sugahara, and Suat Ozbek
- Journal Title
  
  Commun. Integr. Biol
  
  Volume: 4(2) Pages: 150-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011
- Author(s)
  Jiancheng Chen, Shuhei Yamada, Yoshiki Hama, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Naonori Takahashid, Kazuya Hidari, Takashi Suzuki, Yasuo Suzuki, Kazuyuki Sugahara
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 412(1) Pages: 136-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage2011
- Author(s)
  Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada#, and Kazuyuki Sugahara#
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1810(4) Pages: 406-413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Paradoxical effects of chondroitin sulfate-E on Japanese encephalitis viral infection2011
- Author(s)
  Eunmi Kim, Megumi Okumura, Hirofumi Sawa, Tadaaki Miyazaki, Daisuke Fujikura, Shuhei Yamada, Kazuyuki Sugahara, Michihito Sasaki, Takashi Kimura
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 409(4) Pages: 717-722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in α -Thrombomodulin from Human Urine2011
- Author(s)
  Taishi Hashiguchi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 33003-33011
- DOI
  10.1074/jbc.m111.279174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790066
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain2011
- Author(s)
  Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, Kazuyuki Sugahara
- Journal Title
  
  Glycobiology
  
  Volume: 21(5) Pages: 565-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Dermatan sulfate epimerase 2 is the predominant isozyme in the formation of the chondroitin sulfate/dermatan sulfate hybrid structure in postnatal developing mouse brain2011
- Author(s)
  Akatsu, C., Mizumoto, S., Kaneiwa, T., Maccarana, M., Malmstrom,. A., Yamada, S., Sugahara, K.
- Journal Title
  
  Glycobiology
  
  Volume: 21 Pages: 565-574
- DOI
  10.1093/glycob/cwq208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Demonstration of the Hepatocyte Growth Factor Signaling Pathway in the in vitro Neuritogenic Activity of Chondroitin Sulfate from Ray Fish Cartilage2011
- Author(s)
  Taishi Hashiguchi
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 1810 Pages: 406-413
- DOI
  10.1016/j.bbagen.2011.01.001
- NAID
  120002934270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016
[Journal Article] Unique heparan sulfate from shrimp heads exhibits a strong inhibitory effect on infections by dengue virus and Japanese encephalitis virus2011
- Author(s)
  Jiancheng Chen
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 412 Pages: 136-142
- DOI
  10.1016/j.bbrc.2011.07.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057, KAKENHI-PROJECT-23390016
[Journal Article] Evolution of glycosaminoglycans: comparative biochemical study.2011
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Commun. Integr. Biol.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Paradoxical effects of chondroitin sulfate-E on Japanese encephalitis viral infection.2011
- Author(s)
  Kim, E., Okumura, M., Sawa, H., Miyazaki, T., Fujikura, D., Yamada, S., Sugahara, K., Sasaki, M., Kimura, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 409 Pages: 717-722
- DOI
  10.1016/j.bbrc.2011.05.072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016, KAKENHI-PROJECT-23790317
[Journal Article] Evolution of Glycosaminoglycans : Comparative Biochemical Study2011
- Author(s)
  Shuhei Yamada, Kazuyuki Sugahara, Suat Özbek
- Journal Title
  
  Communicative & Integrative Biology
  
  Volume: 4 Pages: 150-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390016
[Journal Article] Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome.2010
- Author(s)
  Miyake N., Kosho T., Mizumoto S., Furuichi T., Hatamochi A., Nagashima Y., Arai E., Takahashi K., Kawamura R., Wakui K., Takahashi J., Kato H., Yasui H., Ishida T., Ohashi H., Nishimura G., Shiina M., Saitsu H., Tsurusaki Y., Doi H., Fukushima Y., Ikegawa S., Yamada S., Sugahara K., Matsumoto N.
- Journal Title
  
  Hum.Mutat.(Equal contribution) 31(8)
  
  Pages: 966-974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Evolution of Glycosaminoglycans : Comparative Biochemical Study.2010
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Communicative & Integrative Biology
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Development of a Mouse Monoclonal Antibody Against the Chondroitin Sulfate-protein Linkage Region Derived from Shark Cartilage2010
- Author(s)
  Chizuru Akatsu, Duriya Fongmoon, Shuji Mizumoto, Jean-Claude Jacquinet, Prachya Kongtawelert, Shuhei Yamada#, and Kazuyuki Sugahara#
- Journal Title
  
  Glycoconjugate J
  
  Volume: 27(4) Pages: 387-399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Identification of Human Hyaluronidase-4 as a Novel Chondroitin Sulfate Hydrolase That Preferentially Cleaves the Galactosaminidic Linkage in the Trisulfated Tetrasaccharide Sequence2010
- Author(s)
  Tomoyuki Kaneiwa, Shuji Mizumoto, Kazuyuki Sugahara, and Shuhei Yamada#
- Journal Title
  
  Glycobiology
  
  Volume: 20(3) Pages: 300-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Analysis of the structure and neuritogenic activity of chondroitin sulfate/dermatan sulfate hybrid chains from porcine fetal membranes.2010
- Author(s)
  Hashiguchi T., Mizumoto S., Yamada S., Sugahara K.
- Journal Title
  
  Glycoconjugate J. 27(1)
  
  Pages: 49-60
- NAID
  120004043734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] A non-sulfated chondroitin stabilizes membrane tubulation in cnidarian organelles.2010
- Author(s)
  Adamczyk P., Zenkert C., Balasubramanian P.G., Yamada S., Murakoshi S., Sugahara K., Hwang J.S., Gojobori T., Holstein T.W., Ozbek S.
- Journal Title
  
  J.Biol.Chem. 285(33)
  
  Pages: 25613-25623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Glycobiology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Involvement of chondroitin sulfate E in the liver tumor focal formation of murine osteosarcoma cells.2009
- Author(s)
  Basappa Murugan S., Sugahara K.N., Lee C.M., ten Dam G.B., van Kuppevelt T.H., Miyasaka M., Yamada S., Sugahara K.
- Journal Title
  
  Glycobiology 19(7)
  
  Pages: 735-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009
- Author(s)
  Shuhei Yamada, Masako Onishi, Reiko Fujinawa, Yuko Tadokoro, Koji Okabayashi, Makoto Asashima, and Kazuyuki Sugahara,
- Journal Title
  
  Glycobiology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Structural and functional changes of sulfated glycosaminoglycans in Xenopus laevis during embryogenesis.2009
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Glycobiology 19
  
  Pages: 488-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Important role of heparan sulfate in postnatal islet growth and insulin secretion.2009
- Author(s)
  Takahashi I., Noguchi N., Nata K., Yamada S., Kaneiwa T., Mizumoto S., Ikeda T., Sugihara K., Asano M., Yoshikawa T., Yamauchi A., Shervani N. J., Uruno A., Kato I., Unno M., Sugahara K., Takasawa S., Okamoto H., Sugawara A.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 383(1)
  
  Pages: 113-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans.2009
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Trends Glycosci.Glycotechnol. 21
  
  Pages: 149-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009
- Author(s)
  Yamada S., Onishi M., Fujinawa R., Tadokoro Y., Okabayashi K., Asashima M., Sugahara K.
- Journal Title
  
  Glycobiology 19(5)
  
  Pages: 488-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis2009
- Author(s)
  huhei Yamada#, Masako Onishi, Reiko Fujinawa, Yuko Tadokoro, Koji Okabayashi, Makoto Asashima, and Kazuyuki Sugahara
- Journal Title
  
  Glycobiology
  
  Volume: 19(5) Pages: 488-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Isolation and Characterization of a Novel Chondroitin Sulfate from Squid LiverIntegument Rich in N-Acetylgalactosamine(4, 6-O-disulfate) and Glucuronate(3-O-sulfate) Residues2009
- Author(s)
  Ajaya Kumar Shetty, Takanari Kobayashi, Shuji Mizumoto, Masaki Narumi, YoshiakiKudo, Shuhei Yamada#, and Kazuyuki Sugahara#
- Journal Title
  
  Carbohydr. Res
  
  Volume: 344(12) Pages: 1526-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Structural and Functional Changes of Sulfated Glycosaminoglycans in Xenopus laevis during Embryogenesis.2009
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Glycobiology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans.2009
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Trends Glycosci. Glycotechnol. 21
  
  Pages: 149-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Isolation and Characterization of a Novel Chondroitin Sulfate from Squid Liver Integument Rich in N-Acetylgalactosamine(4,6-O-disulfate) and Glucuronate(3-O-sulfate) Residues2009
- Author(s)
  Ajaya Kumar Shetty, Takanari Kobayashi, Shuji Mizumoto, Masaki Narumi, Yoshiaki Kudo, Shuhei Yamada, and Kazuyuki Sugahara
- Journal Title
  
  Carbohydr. Res. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Isolation and characterization of a novel chondroitin sulfate from squid liver integument rich in N-acetylgalactosamine(4,6-O-disulfate) and glucuronate(3-O-sulfate) residues.2009
- Author(s)
  Shetty A.K., Kobayashi T., Mizumoto S., Narumi M., Kudo Y., Yamada S., Sugahara K.
- Journal Title
  
  Carbohydr.Res.(Equal contribution) 344(12)
  
  Pages: 1526-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Important Role of Heparan Sulfate in Postnatal Islet Growth and Insulin Secretion2009
- Author(s)
  Iwao Takahashi, Naoya Noguchi, Koji Nata, Shuhei Yamada, Tomoyuki Kaneiwa, Shuji Mizumoto, Takayuki Ikeda, Kazushi Sugihara, Masahide Asano, Takeo Yoshikawa, Akiyo Yamauchi, Nausheen Jamal Shervani, Akira Uruno, Ichiro Kato, Michiaki Unno, Kazuyuki Sugahara, Shin Takasawa, Hiroshi Okamoto, and Akira Sugawara
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 383(1) Pages: 113-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Structural and functional changes of sulfated glycosaminoglycans in Xenopus laevis during embryogenesis.2009
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Glycobiology 19
  
  Pages: 488-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans2009
- Author(s)
  huhei Yamada#, Shuji Mizumoto, and Kazuyuki Sugahara
- Journal Title
  
  Trends Glycosci. Glycotechnol
  
  Volume: 21(119) Pages: 149-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590057
[Journal Article] Chondroitin Hydrolase in Caenorhabditis elegans.2009
- Author(s)
  Yamada S., Mizumoto S., Sugahara K.
- Journal Title
  
  Trends Glycosci.Glycotechnol. 21(119)
  
  Pages: 149-162
- NAID
  10026976542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390019
[Journal Article] Identificationof a Novel Chondroitin Hydrolase inCaenorhabditis elegans. These authorscontributed equally to the work2008
- Author(s)
  Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M. Montano, Souhei Mitani and Kazuyuki Sugahara
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 14971-14979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Potential Therapeutic Application of Chondroitin Sulfate/Dermatan Sulfate2008
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Current Drug Discovery Technologies 5
  
  Pages: 289-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Potential Therapeutic Application ofChondroitin Sulfate/Dermatan Sulfate2008
- Author(s)
  Shuhei Yamada and Kazuyuki Sugahara
- Journal Title
  
  Current Drug Discovery Technologies 5
  
  Pages: 289-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Identification of a novel chondroitin hydrolase in Caenorhabditis elegans.2008
- Author(s)
  Kaneiwa, T., Yamada, S., Mizumoto, S., Montano, A. M., Mitani, S., and Sugahara, K.
- Journal Title
  
  J Biol. Chem. 283(22)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Determination ofIduronic Acid and Glucuronic Acid in SulfatedChondroitin/Dermatan Hybrid Chains by1H-Nuclear Magnetic Resonance Spectroscopy.*These authors contributed equally to the work.2008
- Author(s)
  Fuchuan Li, Shuhei Yamada, Basappa, Ajaya K. Shetty, Makiko Sugiura, and Kazuyuki Sugahara
- Journal Title
  
  Glycoconjugate J. 25
  
  Pages: 603-610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Determination of Iduronic Acid and Glucuronic Acid in Sulfated Chondroitin/Dermatan Hybrid Chains by 1H-Nuclear Magnetic Resonance Spectroscopy.2008
- Author(s)
  Li, F., Yamada, S., Basappa, Shetty, A. K., Sugiura, M., and Sugahara, K.
- Journal Title
  
  Glycoconjugate J. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Chondroitinase-mediatedDegradation of Rare 3-O-Sulfated GlucuronicAcid in Functional Oversulfated Chondroitin Sulfate K and E.2007
- Author(s)
  Duriya Fongmoon, Ajaya Kumar Shetty, Basappa, Shuhei Yamada, Makiko Sugiura,Prachya Kongtawelert, and Kazuyuki Sugahara
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 36895-36904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] StructuralDetermination of Novel SulfatedOctasaccharides Isolated from ChondroitinSulfate of Shark Cartilage and TheirApplication for Characterizing MonoclonalAntibody Epitopes.2007
- Author(s)
  Sarama S. Deepa, Shuhei Yamada, Shigeyuki Fukui, and Kazuyuki Sugahara
- Journal Title
  
  Glycobiology 17
  
  Pages: 631-645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007
- Author(s)
  Yamada, S., Morimoto, H., Fujisawa, T., and Sugahara, K.
- Journal Title
  
  Glycobiology 17(8)
  
  Pages: 886-894
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Novel sulfated octa- and decasaccharides from squid cartilage chondroitin sulfate-E: Sequencing and their application for determination of the epitope structure of monoclonal antibody MO-2252007
- Author(s)
  Deepa, S. S., Kalayanamitra, K, Ito, Y., Kongtawelert, P, Fukui, S., Yamada, S., Mikami, T., and Sugahara, K.
- Journal Title
  
  Biochemistry 46(9)
  
  Pages: 2453-2465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Defective A-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular develonment2007
- Author(s)
  Alexandra Abramsson, Sindhulakshmi Kurup, Marta Busse, Shuhei Yamada, Per Lindblom, Edith Schallmeiner, Denise Stenzel, Dominique Sauvaget, Johan Ledin, Maria Ringvall, Ulf Landegren, Lena Kjellen, GOran Bondjers, Jin-ping Li, Ulf Lindahl, Dorothe Spillmann, Christer Betsholtz, Holger Gerhardt
- Journal Title
  
  Genes Dev. 21(3)
  
  Pages: 316-331
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590078
[Journal Article] Structural Determination of Novel Sulfated Octasaccharides Isolated from Chondroitin Sulfate of Shark Cartilage and Their Application for Characterizing Monoclonal Antibody Epitopes.2007
- Author(s)
  Deepa, S. S., Yamada, S., Fukui, S., and Sugahara, K.
- Journal Title
  
  Glycobiology 17(6)
  
  Pages: 631-645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Structural determination of novel sulfated octasaccharides isolated from chondroitin sulfate of shark cartilage and their application for characterizing monoclonal antibody epitopes2007
- Author(s)
  Sarama S.Deepa, Shuhei Yamada, Shigeyuki Fukui, Kazuyuki Sugahara
- Journal Title
  
  Glycobiology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590078
[Journal Article] Novel sulfated octa-and decasaccharides from squid cartilage chondroitin sulfate-E : Sequencing and application for determination of the epitope structure of monoclonal antibody MO-225.2007
- Author(s)
  Sarama Sathyaseelan Deepa, Kittiwan Kalayanamitra, Yumi Ito, Prachya Kongtaweelert, Shigeyuki Fukui, Shuhei Yamada, Tadahisa Mikami, Kazuyuki Sugahara
- Journal Title
  
  Biochemistry 46 (9)
  
  Pages: 2453-2465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590078
[Journal Article] Glycosaminoglycans in Hydra magnipapillata(Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Glycobiology 17
  
  Pages: 886-894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Glycosaminoglycans in Hydra magnipapillata(Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007
- Author(s)
  Yamada, S.
- Journal Title
  
  Glycobiology 17
  
  Pages: 886-894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Chondroitinase-mediated degradation of rare 3-O-sulfated glucuronic acid in functional oversulfated chondroitin sulfate K and E.2007
- Author(s)
  Fongmoon, D., Shetty, A. K., Basappa, Yamada, S., Sugiura, M., Kongtawelert, P., and Sugahara, K.
- Journal Title
  
  J. Biol. Chem. 282(51)
  
  Pages: 36895-36904
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, sting organelle, and structural characterization of glycosaminoglycans.2007
- Author(s)
  Yamada, S.
- Journal Title
  
  Glycobiology 17
  
  Pages: 886-894
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390030
[Journal Article] Glycosaminoglycans in Hydra magnipapillata(Hydrozoa, Cnidaria) : Demonstration ofChondroitin in the Developing Nematocyst,Sting Organelle, and Structural Characterization of Glycosaminoglycans2007
- Author(s)
  Shuhei Yamada, Hideto Morimoto, ToshitakaFujisawa, and Kazuyuki Sugahara
- Journal Title
  
  Glycobiology 17
  
  Pages: 886-894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590052
[Journal Article] Preface for the Special Issue Entitled The research front line of the biosynthesis and recognition of acidic sugar chains.2006
- Author(s)
  Shuhei Yamada, Akira Seko
- Journal Title
  
  Trends Glycosci.Glycotech. 18(101)
  
  Pages: 163-164
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590078
[Journal Article] Preface for the Special Issue Entitled "The research front line of the biosynthesis and recognition of acidic sugar chains".2006
- Author(s)
  Shuhei Yamada
- Journal Title
  
  Trends in Glycoscience and Glycotechnology 18・101
  
  Pages: 163-164
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590078
[Journal Article] Heparin-binding Growth Factor, Pleiotrophin, Mediates Neuritogenic Activity of Embryonic Pig Brain-derived Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains toward Embryonic Mouse Hippocampal Neurons in Culture.2005
- Author(s)
  Xingfeng Bao, Tadahisa Mikami, Shuhei Yamada, Andreas Faissner, Takashi Muramatsu, Kazuyuki Sugahara
- Journal Title
  
  J.Biol.Chem. 280(10)
  
  Pages: 9180-9191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590078
[Journal Article] Chondroitin Sulfate Characterized by the E-disaccharide Unit Is a Potent Inhibitor of Herpes Simplex Virus Infectivity and Provides the Virus Binding Sites on gro2C Cells.2005
- Author(s)
  Kicki Bergefall, Edward Trybala, Maria Johansson, Toni Uyama, Satomi Naito, Shuhei Yamada, Hiroshi Kitagawa, Kazuyuki Sugahara, Tomas Bergstrom
- Journal Title
  
  J.Biol.Chem. 280(37)
  
  Pages: 32193-32199
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590078
[Journal Article] Embryonic Fibrobasts with a Gene Trap Mutation in Ext1 Produce Short Heparan Sulfate Chains.2004
- Author(s)
  Shuhei Yamada
- Journal Title
  
  J.Biol.Chem. 279・31
  
  Pages: 32134-32141
- Data Source
  KAKENHI-PROJECT-15790056
[Journal Article] Determination of the glycosaminoglycan-protein linkage region oligosaccharide structure of proteoglycans from Drosophila melanogaster and Caenorhabditis elegans.2002
- Author(s)
  山田修平
- Journal Title
  
  J.Biol.Chem. 277(35)
  
  Pages: 31877-31886
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470493
[Journal Article] Determination of the glycosaminoglycan-protein linkage region oligosaccharide structures of proteoglycans from Drosophila melanogaster and Caenorhabditis elegans.2002
- Author(s)
  Yamada, Shuhei
- Journal Title
  
  J.Biol.Chem. 277(35)
  
  Pages: 31877-31886
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470493
[Patent] コンドロイチン硫酸オリゴ糖の製造方法2012
- Inventor(s)
  松嶋景一郎,浦晴雄,鎌田樹志,宮本宜之,菅原一幸,山田修平
- Industrial Property Rights Holder
  地方独立行政法人北海道立総合研究機構,丸共水産株式会社,国立大学法人北海道大学
- Industrial Property Number
  2012-035546
- Filing Date
  2012-02-21
- Data Source
  KAKENHI-PROJECT-21590057
[Patent] コンドロイチン硫酸オリゴ糖の製造方法2012
- Inventor(s)
  松嶋景一郎, 浦晴雄, 鎌田樹志, 宮本宜之, 菅原一幸, 山田修平
- Industrial Property Rights Holder
  地方独立行政法人北海道立総合研究機構, 丸共水産株式会社, 国立大学法人北海道大学
- Industrial Property Number
  2012-035546
- Filing Date
  2012-02-21
- Data Source
  KAKENHI-PROJECT-21590057
[Patent] グリコサミノグリカン分解促進剤2009
- Inventor(s)
  菅原一幸、山田修平、水本秀二、金岩知之
- Industrial Property Rights Holder
  北海道大学
- Industrial Property Number
  2009-238490
- Filing Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20390019
[Patent] グリコサミノグリカン分解促進剤2009
- Inventor(s)
  菅原一幸, 山田修平, 水本秀二, 金岩知之
- Industrial Property Rights Holder
  北海道大学
- Industrial Property Number
  2009-238490
- Filing Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20390019
[Patent] グリコサミノグリカン分解促進剤2009
- Inventor(s)
  菅原一幸,山田修平,水本秀二,金岩知之
- Industrial Property Rights Holder
  国立大学法人北海道大学
- Industrial Property Number
  2009-238490
- Filing Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21590057
[Patent] グリコサミノグリカン分解促進剤2009
- Inventor(s)
  菅原一幸, 山田修平, 水本秀二, 金岩知之
- Industrial Property Rights Holder
  北海道大学
- Industrial Property Number
  2009-238490
- Filing Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21590057
[Patent] ムコ多糖分解促進剤2007
- Inventor(s)
  菅原一幸, 山田修平, 水本秀二
- Industrial Property Rights Holder
  北海道大学
- Filing Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-19590052
[Patent] ムコ多糖分解促進剤2007
- Inventor(s)
  菅原一幸, 山田修平, 水本秀二
- Industrial Property Rights Holder
  北海道大学
- Industrial Property Number
  2007-291424
- Filing Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-19590052
[Patent] ムコ多糖分解促進剤2007
- Inventor(s)
  菅原一幸, 山田修平, 水本秀二
- Industrial Property Rights Holder
  北海道大学
- Industrial Property Number
  2007-291424
- Filing Date
  2007-11-09
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] A novel type of spondylo-epi-metaphyseal dysplasia with immuno-deficiency caused by mutation in EXTL3 encoding a glycosyltransferase responsible for biosynthesis of heparan sulfate2018
- Author(s)
  Shuji Mizumoto, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shuhei Yamada, and Shiro Ikegawa
- Organizer
  The 11th International Symposium on Glycosyltransferases, Qingdao, China, 6/19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Structural studies on heparan sulfate produced by the lymphoblastoid cell lines prepared from a patient with a mutation in EXTL3 and embryonic cells from Extl3-deficient mice2018
- Author(s)
  Shuhei Yamada, Shuji Mizumoto, Hirofumi Ohashi, Etsuko Sakasai, Nursel H Elcioglu, Noriko Miyake, Naomichi Matsumoto, Daisuke Ibi, Akira Sugawara, and Shiro Ikegawa
- Organizer
  Gordon Research Conference on Proteoglycans 2018, Andover, Poster, USA, 7/8-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] リンパ芽球様細胞株の産生するグリコサミノグリカンの解析2018
- Author(s)
  篠田はるか、持永磨奈美、伊藤有沙、水本秀二、逆井悦子、大橋博文、山田修平
- Organizer
  第64回日本薬学会東海支部総会・大会、名古屋、6/30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Pathophysiological investigation of musculocontractural EDS caused by mutations in CHST14 using knock-out mice2018
- Author(s)
  Takahiro Yoshizawa, Shuji Mizumoto, Yuki Takahashi, Shin Shimada, Kazuyuki Sugahara, Jun Nakayama, Shin’ichi Takeda, Yoshihiro Nomura, Yuko Nitahara-Kasahara, Takashi Okada, Kiyoshi Matsumoto, Shuhei Yamada, Tomoki Kosho
- Organizer
  The International Symposium on the Ehlers-Danlos Syndromes (EDS2018),Ghent, Belgium, 9/28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Structural studies on heparan sulfate produced by the lymphoblastoid cell lines prepared from a patient with a mutation in EXTL3 and embryonic cells from Extl3-deficient mice2018
- Author(s)
  Shuhei Yamada, Shuji Mizumoto, Hirofumi Ohashi, Etsuko Sakasai, Nursel H Elcioglu, Noriko Miyake, Naomichi Matsumoto, Daisuke Ibi, Akira Sugawara, Shiro Ikegawa
- Organizer
  Gordon Research Conference on Proteoglycans 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06670
[Presentation] 免疫異常を伴う脊椎骨端骨幹端異形成症はヘパラン硫酸の生合成を担うEXTL3の変異により引き起こされる2018
- Author(s)
  水本秀二、Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, 松本直通、三宅紀子、西村　玄、山田修平、池川志郎
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-18K06670
[Presentation] ナノ液体クロマトグラフィータンデム質量分析法を用いたエーラス・ダンロス症候群の診断法の開発2018
- Author(s)
  山田和夫、渡辺淳、古庄知己、水本秀二、山田修平、竹下治男、松本健一
- Organizer
  第50回日本結合組織学会学術大会、福岡、6/30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 免疫異常を伴う脊椎骨端骨幹端異形成症はヘパラン硫酸の生合成を担うEXTL3の変異により引き起こされる2018
- Author(s)
  水本秀二, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak,松本直通, 三宅紀子, 西村玄, 山田修平, 池川志郎
- Organizer
  第37回日本糖質学会年会、仙台、8/30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Musculocontractural Ehlers-Danlos syndrome caused by a CHST14 deficiency results in defect in urinary dermatan sulfate2018
- Author(s)
  Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, Kazuyuki Sugahara, Shuhei Yamada
- Organizer
  The International Symposium on the Ehlers-Danlos Syndromes (EDS2018),Ghent, Belgium, 9/27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] リンパ芽球様細胞株の産生するグリコサミノグリカンの解析2018
- Author(s)
  篠田はるか、持永磨奈美、伊藤有沙、水本秀二、逆井悦子、大橋博文、山田修平
- Organizer
  第64回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-18K06670
[Presentation] ヘパラン硫酸の生合成を担うEXTL3の変異は免疫不全を伴う脊椎骨端骨幹端異形成症を引き起こす2018
- Author(s)
  水本秀二, Long Guo, Nursel H Elcioglu, Zheng Wang, Bilge Noyan, Hatice M Albayrak, 松本直通, 三宅紀子, 西村玄, 山田修平, 池川志郎
- Organizer
  糖鎖科学中部拠点　第15回若手の力フォーラム、静岡、9/6
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ヘパラン硫酸生合成酵素であるEXTL3の変異は免疫異常を伴う新たなタイプの脊椎骨端骨幹端異形成症を引き起こす2018
- Author(s)
  Long Guo, Nursel H Elcioglu, Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura, Shiro Ikegawa
- Organizer
  日本生化学会中部支部第82回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-18K06670
[Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates chondroitin sulfate cleavage neo-epitopes2018
- Author(s)
  Brooke Farrugia, Megan Lord, Shuji Mizumoto, Shuhei Yamada, Bruce Caterson, John Whitelock
- Organizer
  The AWTRS/MEPSA/ASDR Cutaneous Biology Meeting 2018, Brisbane, Australia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Structural alteration of glycosaminoglycan side chains and spatial disorganization of collagen networks in the skin of patients with musculocontractural Ehlers-Danlos syndrome caused by CHST14/D4ST1 deficiency2018
- Author(s)
  Tomoki Kosho, Takuya Hirose, Naoki Takahashi, Prasarn Tangkawattana, Jun Minaguchi, Shuji Mizumoto Shuhei Yamada; Noriko Miyake, Atsushi Hatamochi, Jun Nakayama, Tomomi Yamaguchi, Kazushige Takehana
- Organizer
  American Society of Human Genetics (ASHG) 2018, San Diego, USA, 10/19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ヘパラン硫酸生合成酵素であるEXTL3の変異は免疫異常を伴う新たなタイプの脊椎骨端骨幹端異形成症を引き起こす2018
- Author(s)
  Long Guo, Nursel H Elcioglu, Shuji Mizumoto, Zheng Wang, Bilge Noyan, Hatice M Albayrak, Shuhei Yamada, Naomichi Matsumoto, Noriko Miyake, Gen Nishimura1, Shiro Ikegawa
- Organizer
  日本生化学会中部支部第82回例会・シンポジウム、岐阜、5/19
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] McEDS-CHST14患者におけるデコリン糖鎖変異のI型コラーゲン細線維形成に及ぼす影響2018
- Author(s)
  橋本綾菜、野村義宏、広瀬拓哉、竹花一成、美名口順、水本秀二、山田修平、古庄知己、笠原優子、岡田尚巳
- Organizer
  第50回日本結合組織学会学術大会、福岡、6/29
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells: its role in modulating the structure of chondroitin sulfate and regulating tissue remodeling2018
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, James Melrose, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
- Organizer
  Gordon Research Conference on Proteoglycans 2018, , Andover, Poster, USA, 7/8-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] コンドロイチン硫酸／デルマタン硫酸生合成酵素の先天的欠損による遺伝性疾患2018
- Author(s)
  山田修平
- Organizer
  第31回日本軟骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] ルイス肺がん細胞の腫瘍形成におけるRAGE欠損の影響2018
- Author(s)
  鈴木麻未、幸村省吾、水本秀二、菅原一幸、山田修平
- Organizer
  第64回日本薬学会東海支部総会・大会、名古屋、6/30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Human mast cells produce the mammalian chondroitinase, hyaluronidase 4, and generate unique chondroitin sulphate structures2018
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
- Organizer
  Matrix Biology Society of Australia and New Zealand, Annual Meeting 2018, Auckland, New Zealand, 12/6
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] デルマタン硫酸エピメラーゼ欠損によるmusculocontractural Ehlers-Danlos Syndromeの既報告3例と新規3例における臨床像の検討2017
- Author(s)
  〇運﨑愛、Charlotte Kvist Lautrup、Keng Wee Teik、水本秀二、Heng Hock Sin、Irene Kibaek Nielsen、Sara Markholt、山田修平、松本直通、三宅紀子、古庄知己
- Organizer
  日本人類遺伝学会第62回大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 発生段階の異なるマウス脳におけるグリコサミノグリカン分解酵素の発現解析2017
- Author(s)
  禰津瑠里子、三輪一貴、水本秀二、山田修平
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] 発達段階の脳におけるコンドロイチン硫酸/ヒアルロン酸分解酵素の発現解析2017
- Author(s)
  山田修平、三輪一貴、水本秀二
- Organizer
  第49回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] ヒアルロニダーゼ1および４の基質認識に関与するアミノ酸残基の解析2017
- Author(s)
  白水仁子、小林智恵里、稲葉史恵、安部優貴子、水本秀二、山田修平
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] 中枢神経系におけるコンドロイチン硫酸/ヒアルロン酸の分解機構に関する研究2017
- Author(s)
  永井冴、藤井貴夢、水本秀二、山田修平
- Organizer
  平成28年度　新学術領域「神経糖鎖生物学」最終シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Ehlers-Danlos syndrome caused by mutations in CHST14/D4ST1 results in defect of urinary dermatan sulfate2017
- Author(s)
  Shuji Mizumoto, ◯Shuhei Yamada, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Tomomi Yamaguchi, Nobuhiko Okamoto, Noriko Miyake, and Kazuyuki Sugahara
- Organizer
  7 Lakes Proteoglycans Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ルイス肺がん細胞による腫瘍形成におけるRAGE の役割に関する研究2017
- Author(s)
  ○幸村省吾、鈴木麻未、水本秀二、菅原一幸、山田修平
- Organizer
  第63 回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 脊髄損傷モデルマウスへのヒアルロニダーゼの投与2017
- Author(s)
  直井友弥、柴本秀太、水本秀二、勝又優子、森岡　幸、武内恒成、山田修平
- Organizer
  第63回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸を特異的に加水分解するヒアルロニダーゼ４の細胞内局在の解析2017
- Author(s)
  牧野冴紀、水本秀二、山田修平
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸は細胞外ヒストンによる血管内皮障害を介した臓器障害を抑制する2017
- Author(s)
  ○長野文彦、水野智博、水本秀二、吉岡憲吾、高橋和男、坪井直毅、丸山彰一、山田修平、永松正
- Organizer
  日本医療薬学会第１回フレッシャーズカンファレンス
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] マウス脳の各発達過程におけるヒアルロン酸代謝関連酵素の発現の定量的解析2017
- Author(s)
  山田修平、三輪一貴、水本秀二
- Organizer
  平成28年度　新学術領域「神経糖鎖生物学」最終シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates CS cleavage neo-epitopes2017
- Author(s)
  〇Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, and John M. Whitelock
- Organizer
  7 Lakes Proteoglycans Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] The mammalian chondroitinase, hyaluronidase 4, is produced by human mast cells and generates CS cleavage neo-epitopes2017
- Author(s)
  Brooke L. Farrugia, Shuji Mizumoto, Megan S. Lord, Shuhei Yamada, Bruce Caterson, John M. Whitelock
- Organizer
  7 Lakes Proteoglycan Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Development of diagnostic method of Ehlers-Danlos syndrome using nano-LC/MS/MS2017
- Author(s)
  ◯山田和夫、渡辺淳、古庄知己、水本秀二、山田修平、竹下治男、松本健一
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）、第40回日本分子生物学会年会、第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ヒアルロニダーゼ1および４の基質認識に関与するアミノ酸残基の解析2017
- Author(s)
  小林智恵里、白水仁子、稲葉史恵、安部優貴子、水本秀二、山田修平
- Organizer
  第63回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸およびヘパリンはヒストンにより誘発された致死性血栓症を軽減する2017
- Author(s)
  ○長野文彦、水野智博、水本秀二、高橋和男、坪井直毅、丸山彰一、山田修平、永松正
- Organizer
  第63 回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins2017
- Author(s)
  ◯Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, Jessica C. F. Kwok, and Kazuyuki Sugahara
- Organizer
  平成28年度　新学術領域「神経糖鎖生物学」最終シンポジウム
- Place of Presentation
  JPタワー名古屋(名古屋)
- Year and Date
  2017-03-03
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 脳・神経系におけるコンドロイチン硫酸/ヒアルロン酸分解機構に関する研究2016
- Author(s)
  山田修平、永井冴、三輪一貴、水本秀二
- Organizer
  第48回日本結合組織学会学術大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Multiple fractures and severe osteoporosis caused by mutations in a glycosyltransferase responsible for biosynthesis of glycosaminoglycans2016
- Author(s)
  ◯Shuji Mizumoto, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, Shuhei Yamada, Katrin Hoffman, Kazuyuki Sugahara, Emily Farrow
- Organizer
  The 10th International Symposium on Glycosyltransferases (GlycoT2016)
- Place of Presentation
  The Hospital for Sick Children (Tronto, Canada)
- Year and Date
  2016-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Studies on the mechanism of degradation of chondroitin sulfate/hyaluronan in central nervous system2016
- Author(s)
  Shuhei Yamada, Sae Nagai, Shuji Mizumoto
- Organizer
  XXVIII International Carbohydrate Symposium
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Investigation of the amino acid residues in hyaluronidases-1 and -4 responsible for their substrate recognition2016
- Author(s)
  Yukiko Abe, Kentaro Yamagiwa, Shuji Mizumoto, Shuhei Yamada
- Organizer
  XXVIII International Carbohydrate Symposium
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸に特異的な加水分解酵素であるHYAL4の酵母 (Pichia pastoris) での発現および精製2016
- Author(s)
  柴本秀太、杉田真千子、水本秀二、菅原一幸、山田修平
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] デルマタン4-O-硫酸基転移酵素-1の欠損によるエーラス・ダンロス症候群患者由来の尿中デルマタン硫酸の定量解析2016
- Author(s)
  ◯水本秀二、古庄知己、籏持淳、本田智子、山田修平、菅原一幸
- Organizer
  日本薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2016
- Place of Presentation
  長良川国際会議場・岐阜都ホテル(岐阜)
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] Quantification of dermatan sulfate from urine in Ehlers-Danlos syndrome caused by carbohydrate sulfotransferase 14 (CHST14)/dermatan 4-O-sulfotransferase-1 (D4ST1) deficiency2016
- Author(s)
  ◯Shuji Mizumoto, Tomoki Kosho, Atsushi Hatamochi, Tomoko Honda, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  XXVIII International Carbohydrate (ICS2016)
- Place of Presentation
  Marriott Hotel (New Orleans, USA)
- Year and Date
  2016-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] ヒアルロニダーゼ1および4におけるコンドロイチン硫酸およびヒアルロン酸の認識に関わるアミノ酸残基の解析2016
- Author(s)
  山田修平、安倍優貴子、山極健太郎、水本秀二
- Organizer
  第48回日本結合組織学会学術大会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] デルマタン硫酸の生合成不全によるエーラス・ダンロス症候群の糖鎖生物学的研究2016
- Author(s)
  水本秀二, 古庄知己, 本田智子,中島正宏, Thomas Muller, 三宅紀子, 籏持淳, 松本直通, Andreas R Janecke, 池川志郎, 菅原一幸, ○山田修平
- Organizer
  第35回日本糖質学会年会
- Place of Presentation
  高知市文化プラザ（高知）
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] 多発性骨折と骨粗鬆症はグリコサミノグリカンの生合成に関わる糖転移酵素の変異によって引き起こされる2016
- Author(s)
  ◯水本秀二, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, 山田修平, Katrin Hoffman, 菅原一幸, Emily Farrow
- Organizer
  糖鎖科学中部拠点第13回若手の力フォーラム
- Place of Presentation
  岐阜大学(岐阜）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] エーラス・ダンロス症候群患者由来の尿中デルマタン硫酸の定量2016
- Author(s)
  ◯水本秀二, 古庄知己, 籏持淳, 本田智子, 山田修平, 菅原一幸
- Organizer
  第８０回日本生化学会中部支部例会・シンポジウム
- Place of Presentation
  三重大学講堂（津）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] グリコサミノグリカンの生合成に関わる糖転移酵素の変異による多発性骨折と骨粗鬆症2016
- Author(s)
  ◯水本秀二, Florian Job, Laurie Smith, Natario Couser, Ashley Brazil, Howard Saul, Melanie Patterson, Margaret I. Gibson, Sarah Soden, Neil Miller, Isabelle Thiffault, Carol Saunders, 山田修平, Katrin Hoffman, 菅原一幸, Emily Farrow
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台国際センター・東北大学川内北キャンパス (仙台)
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-16K08251
[Presentation] マウス脳におけるコンドロイチン硫酸とヒアルロン酸の分解活性の検出2016
- Author(s)
  石川輝、水本秀二、山田修平
- Organizer
  第62回日本薬学会東海支部総会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Detection of the degradation activities of chondroitin sulfate and hyaluronan in mouse brain as well as cultured cell lines2016
- Author(s)
  ◯Shuji Mizumoto, Tomomasa Yamanaka, Sae Nagai, and Shuhei Yamada
- Organizer
  The 3rd International Symposium on Glyco-Neuroscience
- Place of Presentation
  淡路夢舞台国際会議場（淡路）
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860037
[Presentation] コンドロイチン硫酸に特異的な加水分解酵素であるHYAL4の酵母（Pichia pastoris）での発現および精製2016
- Author(s)
  柴本秀太、杉田真千子、水本秀二、菅原一幸、山田修平
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸を特異的に加水分解するヒアルロニダーゼ４の細胞内局在の解析2016
- Author(s)
  三輪茜音、水本秀二、山田修平
- Organizer
  第62回日本薬学会東海支部総会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Quantitative analysis of the expression of hyaluronan-chondroitin sulfate-degrading enzymes in the mouse brain during development.2016
- Author(s)
  Kazutaka Miwa, Shuji Mizumoto, Shuhei Yamada
- Organizer
  XXVIII International Carbohydrate Symposium
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2015
- Author(s)
  三谷真夕、水本秀二、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Quantitative Analysis of the Expression of Hyaluronidases in the Mouse Brain during Development2015
- Author(s)
  Mayu Mitani, Shuji Mizumoto, Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] 酵母（Pichia pastoris）を用いたヒアルロニダーゼ４の発現及び精製2015
- Author(s)
  杉田真千子、柴本秀太、水本秀二、菅原一幸、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] サケ鼻軟骨由来のコンドロイチン硫酸プロテオグリカンの構造解析2015
- Author(s)
  横井友哉、松崎南美、桝谷晃明、坪井誠、菅原一幸、山田修平
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザインクリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] Quantitative Analysis of the Expression of Hyaluronidases in the Mouse Brain during Development2015
- Author(s)
  Mayu Mitani, Shuji Mizumoto, Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Investigation of the Amino Acid Residue Responsible for Diferrent Substrate Specificity of Hyaluronidases-1 and -42015
- Author(s)
  Kentaro Yamagiwa, Haruna Iwatsuki, Yukiko Abe, Shuji Mizumoto, and Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] ヒアルロニダーゼ1および4におけるコンドロイチン硫酸およびヒアルロン酸の認識に関わるアミノ酸残基の解析2015
- Author(s)
  安倍優貴子、山極健太郎、岩月遥奈、水本秀二、山田修平
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] ヒアルロニダーゼ1および4におけるコンドロイチン硫酸およびヒアルロン酸の認識に関わるアミノ酸残基の解析2015
- Author(s)
  安倍優貴子、山極健太郎、岩月遥奈、水本秀二、山田修平
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2015
- Author(s)
  三谷真夕、水本秀二、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] 脳・神経系に由来する培養細胞株を用いたコンドロイチン硫酸/ヒアルロン酸分解活性の検出2015
- Author(s)
  永井冴、山中智正、水本秀二、山田修平
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] 酵母（Pichia pastoris）を用いたヒアルロニダーゼ４の発現及び精製2015
- Author(s)
  杉田真千子、柴本秀太、水本秀二、菅原一幸、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] Cellular Localization of Chondroitin Sulfate Hydrolase, Hyaluronidase-42015
- Author(s)
  Yumiko Nomura, Shuji Mizumoto, and Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] ヒトの癌細胞株や癌組織におけるヒアルロニダーゼ4の発現解析2015
- Author(s)
  西島大樹、水本秀二、山田修平
- Organizer
  第61回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] Investigation of the Amino Acid Residue Responsible for Diferrent Substrate Specificity of Hyaluronidases-1 and -42015
- Author(s)
  Kentaro Yamagiwa, Haruna Iwatsuki, Yukiko Abe, Shuji Mizumoto, and Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] サケ鼻軟骨由来のコンドロイチン硫酸プロテオグリカンの構造解析2015
- Author(s)
  横井友哉、松崎南美、桝谷晃明、坪井誠、菅原一幸、山田修平
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザインクリエイティブセンター神戸（神戸）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Cellular localization of chondroitin sulfate hydrolase, hyaluronidase－42015
- Author(s)
  Yumiko Nomura, Shuji Mizumoto, and Shuhei Yamada
- Organizer
  9th International Conference on Proteoglycans and 10th Pan-Pacific Connective Tissue Societies Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2015-08-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] ヒアルロニダーゼ1と4の基質認識の違いに関与するアミノ酸残基の解析2015
- Author(s)
  山極健太郎、岩月遥奈、安倍優貴子、水本秀二、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] ヒアルロニダーゼ1と4の基質認識の違いに関与するアミノ酸残基の解析2015
- Author(s)
  山極健太郎、岩月遥奈、安倍優貴子、水本秀二、山田修平
- Organizer
  第34回日本糖質学会年会
- Place of Presentation
  東京
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PROJECT-15K07951
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の細胞内局在の解析2014
- Author(s)
  森本千夏、野村優美子、水本秀二、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] グリコサミノグリカンの代謝2014
- Author(s)
  山田　修平
- Organizer
  第8回東北糖鎖研究会
- Place of Presentation
  岩手医科大学（矢巾町、岩手）
- Year and Date
  2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Role of Hyaluronidases in the Catabolism of Chondroitin Sulfate2014
- Author(s)
  Shuhei Yamada
- Organizer
  10th International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
- Place of Presentation
  Kolkata, India
- Invited
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Expression Analysis of Hyaluronidases in the Mouse Brain during Development2014
- Author(s)
  Yuka Oiwa, Shuji Mizumoto, Ryoji Kojima, Tadashi Nagamatsu, Shuhei Yamada
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research “Glycans in Neuroscience”
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] 妊娠マウスにおける膵臓ランゲルハンス島のヘパラン硫酸の構造変化2014
- Author(s)
  松崎南美、西田祐美、高橋巌、那谷耕司、山田修平
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] ヒトヒアルロニダーゼの基質認識に必要なアミノ酸残基の解析2014
- Author(s)
  岩月遥奈、水本秀二、金岩知之、菅原一幸、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Integrated neuroglycobiology for proteoglycans and chondroitin sulfate-binding proteins2014
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, Kosei Takeuchi, Yoshiaki Nakayama, Akira Kurosaka, Keiichiro Matsushima, Nobuyuki Miyamoto, Wataru Takada, Hirofumi Kodera, Naomichi Matsumoto, Hirotomo Saitsu, Gunnar Dick, James W. Fawcett, Jessica C. F. Kwok
- Organizer
  International Symposium on Glyco-Neuroscience
- Place of Presentation
  Awaji
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2014
- Author(s)
  大岩友香、水本秀二、小島良二、永松正、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] ヒトヒアルロニダーゼの基質認識に必要なアミノ酸残基の解析2014
- Author(s)
  岩月遥奈、水本秀二、金岩知之、菅原一幸、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の細胞内局在の解析2014
- Author(s)
  森本千夏、野村優美子、水本秀二、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] グリコサミノグリカンの代謝2014
- Author(s)
  山田　修平
- Organizer
  第8回東北糖鎖研究会
- Place of Presentation
  岩手医科大学（矢巾町、岩手）
- Year and Date
  2014-10-10
- Invited
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] コンドロイチン硫酸代謝におけるヒアルロニダーゼの役割2014
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  第46回日本結合組織学会学術大会第61回マトリックス研究会大会合同学術集会
- Place of Presentation
  ウインク愛知（名古屋）
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] 発生段階の異なるマウス脳におけるヒアルロニダーゼファミリーメンバーの発現解析2014
- Author(s)
  大岩友香、水本秀二、小島良二、永松正、山田修平
- Organizer
  第60回日本薬学会東海支部総会
- Place of Presentation
  鈴鹿医療大学（鈴鹿）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] コンドロイチン硫酸代謝におけるヒアルロニダーゼの役割2014
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  第46回日本結合組織学会学術大会第61回マトリックス研究会大会合同学術集会
- Place of Presentation
  名古屋大学（名古屋）
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system2013
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  The 13th International Conference on Functional and Medical Foods with Bioactive Compounds : Science and Practical Applications/The First International Symposium of Academic Society for Functional Foods and Bioactive Compounds
- Place of Presentation
  The Kyoto Prefectural University (Kyoto)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] グリコサミノグリカンの生合成・代謝・機能の研究2013
- Author(s)
  山田修平
- Organizer
  糖鎖化学中部拠点　第11回「若手の力」フォーラム
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2013
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Kittiwan Kalayanamitra, Shuhei Yamada, and Prachya Kongtawelert
- Organizer
  8th International Conference on Proteoglycans
- Place of Presentation
  Frankfurt, Germany
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] マイクロ化学プロセスを利用したコンドロイチン硫酸オリゴ糖の大量調製方法の確立2013
- Author(s)
  山田修平、松嶋景一郎、浦晴雄、宮本宣之、菅原一幸
- Organizer
  第32回日本糖質学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] 第59回日本薬学会東海支部総会2013
- Author(s)
  山田修平、松嶋景一郎、浦晴雄、宮本宣之、菅原一幸
- Organizer
  第59回日本薬学会東海支部総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Mass Preparation of Oligosaccharides with Intestinal Absorption Capacity by Hydrolysis of Chondroitin Sulfate Polysaccharides with Subcritical Water Microreaction System2013
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  13th International Conference of FFC and 1st International Symposium of Academic Society for Functional Foods and Bioactive Compounds
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] ヒアルロニダーゼはコンドロイチン4-硫酸に対しヒアルロン酸と同程度の強い加水分解活性をもつ2013
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] ヒトとマウスにおけるコンドロイチン硫酸加水分解酵素の基質特異性の違いに関わるアミノ酸残基の同定2013
- Author(s)
  山田修平、金岩知之、宮崎杏、古川諒、水本秀二、菅原一幸
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Studies on the Role of Hyaluronidases in the Catabolism of Chondroitin Sulfate2013
- Author(s)
  Shuhei Yamada
- Organizer
  8th International Conference on Proteoglycans
- Place of Presentation
  Frankfurt, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] マイクロ化学プロセスによる新規糖鎖食品の開発2013
- Author(s)
  松嶋景一郎、浦晴雄、宮本宣之、菅原一幸、山田修平、水本秀二
- Organizer
  北海道立総合研究機構　技術移転フォーラム2013
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離2012
- Author(s)
  水本秀二,村越早織,Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場およびマリンメッセ福岡、(ポスター発表)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の酵素活性に必要なアミノ酸残基の同定2012
- Author(s)
  山田修平、金岩知之、宮崎杏、水本秀二、菅原一幸
- Organizer
  第５８回日本薬学会東海支部総会・大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] コンドロイチン硫酸特異的加水分解酵素の発現組織の解析およびその機能の研究2012
- Author(s)
  古川諒、金岩知之、宮崎杏、菅原一幸、山田修平
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] コンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の酵素活性に必要なアミノ酸残基の同定2012
- Author(s)
  金岩知之、宮崎杏、水本秀二、菅原一幸、山田修平
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] 哺乳類におけるコンドロイチン硫酸特異的加水分解酵素ヒアルロニダーゼ-4の基質認識に必要なアミノ酸残基の同定2012
- Author(s)
  Shuhei Yamada
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] ヒアルロニダーゼの本来の基質はヒアルロン酸ではなくコンドロイチン硫酸2012
- Author(s)
  山田修平、本田智子、金岩知之、水本秀二、菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Shrimp head heparan sulfate with unique structure and function2012
- Author(s)
  Yoshiki Hama, Chen Jiancheng, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Kazuyuki Sugahara, Shuhei Yamada
- Organizer
  The IGP International Symposium 2012
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸に特異的な加水分解酵素に関する研究2012
- Author(s)
  山田修平，金岩知之，宮崎杏，古川諒，水本秀二，菅原一幸
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] ヒトヒアルロニダーゼはコンドロイチン硫酸Aをヒアルロン酸と同程度の速度で加水分解する2012
- Author(s)
  本田智子、金岩知之、水本秀二、菅原一幸、山田修平
- Organizer
  第49回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development2012
- Author(s)
  Shuji Mizumoto, Saori Murakoshi,Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fukui, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2012年度包括型脳科学研究推進支援ネットワーク・夏のワークショップ
- Place of Presentation
  仙台国際センター、(ポスター発表)
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] ヒトヒアルロニダーゼのコンドロイチン４硫酸に対する高い加水分解活性2012
- Author(s)
  本田智子、金岩知之、水本秀二、菅原一幸、山田修平
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] ユニークな構造と機能をもつエビ頭部に由来するヘパラン硫酸2012
- Author(s)
  羽磨紀城, 陳建成, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, Eunmi Kim, 木村享史, 菅原一幸, 山田修平
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] 「Shrimp head heparan sulfate with unique structure and function2012
- Author(s)
  Yoshiki Hama, Chen Jiancheng, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Eunmi Kim, Takashi Kimura, Kazuyuki Sugahara, Shuhei Yamada
- Organizer
  The IGP International Symposium 2012
- Place of Presentation
  Sapporo
- Year and Date
  2012-03-02
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] コンドロイチン硫酸特異的加水分解酵素の発現組織の解析および精巣における機能の研究2012
- Author(s)
  古川諒、金岩知之、宮崎杏、菅原一幸、山田修平
- Organizer
  日本薬学会北海道支部137例会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] エビ頭部に由来するヘパラン硫酸の構造と生物活性2011
- Author(s)
  羽磨紀城、陳建成、Ajaya Kumar Shetty、小林孝成、織田浩司、清木興介、Eunmi Kim、木村享史、菅原一幸、山田修平
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(新潟県)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の欠損による骨・皮膚疾患2011
- Author(s)
  水本秀二,三宅紀子,古庄知己, Mirjam H.H. van Roij, Beyhan Tuysuz,Stefan Mundlos, Stephen P. Robertson, 山田修平, 松本直通, 菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール、(口頭発表)
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E構造の発現低下による転移抑制2011
- Author(s)
  水本秀二、渡邊基夫、山田修平、菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] エビ頭部由来ヘパラン硫酸の構造と機能の研究2011
- Author(s)
  陳建成、羽磨紀城、Ajaya Kumar Shetty、小林孝成、織田浩司、清木興介、木村享史、高橋尚徳、左一八、鈴木隆、鈴木康夫、〇山田修平、菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] コンドロイチン硫酸/デルマタン硫酸の生合成に関わる酵素の欠損による骨・皮膚疾患2011
- Author(s)
  ○水本秀二, 三宅紀子, 古庄知己, Mirjam H.H. van Roij, Beyhan Tuysuz, Stefan Mundlos, Stephen P. Robertson, 山田修平, 松本直通, 菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(新潟県)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] エビ頭部に由来するヘパラン硫酸の構造と生物活性2011
- Author(s)
  羽磨紀城, 陳建成, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, Eunmi Kim, 木村享史, 菅原一幸, 山田修平
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(長岡市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Studies on novel mammalian endo-type chondroitin sulfate hydrolases2011
- Author(s)
  T. Kaneiwa, A. Miyazaki, S. Mizumoto, K. Sugahara, S. Yamada
- Organizer
  The 3rd FEBS-MPST Advanced Lecture Course on Matrix Pathobiology, Signaling andMolecular Targets (FEBS-MPST2011).
- Place of Presentation
  Spetses, Greece
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Mouse hyaluronidase-4 : Identification of a chondroitin sulfate-specific hydrolase with distinct specificity from human hyaluronidase-42011
- Author(s)
  S. Yamada, A. Miyazaki, T. Kaneiwa, S. Mizumoto, and K. Sugahara
- Organizer
  The 31st Naito Conference. Glycan Expression and Regulation [II]: Metabolites, Stress Response, Microdomains, and Beyond.
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] コンドロイチン硫酸E構造の発現調節によるルイス肺癌細胞の転移抑制2011
- Author(s)
  水本秀二、渡邊基夫、山田修平、菅原一幸
- Organizer
  日本薬学会北海道支部第136例会
- Place of Presentation
  札幌コンベンションセンター、(口頭発表)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011
- Author(s)
  Shuhei Yamada
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  QSTATION (Australia)
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Chondroitin sulfate-specific novel hydrolase in human2011
- Author(s)
  山田修平
- Organizer
  9th International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
- Place of Presentation
  Trivandrum, Kerala, India
- Year and Date
  2011-01-28
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Specific interaction of the envelope glycoproteins E1 and E2 with liver heparan sulfate involved in the tissue tropismatic infection by hepatitis C virus2011
- Author(s)
  Shuhei Yamada
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Mouse hyaluronidase-4 : Identification of a chondroitin sulfate-specific hydrolase with distinct specificity from human hyaluronidase-42011
- Author(s)
  Shuhei Yamada
- Organizer
  The 31st Naito Conference. Glycan Expression and Regulation [II] : Metabolites, Stress Response, Microdomains, Beyond
- Place of Presentation
  CHATERAISE Gateaux Kingdom (Sapporo)
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] 新規のコンドロイチン硫酸に特異的な加水分解酵素の同定2011
- Author(s)
  山田修平
- Organizer
  第19回糖質関連酵素化学シンポジウム
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E構造の発現低下による転移抑制2011
- Author(s)
  渡邊基夫、水本秀二、山田修平、菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(新潟県)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Analysis of the expression pattern of dermatan sulfate epimerase-2, which is involved in the bipolar disorder, in the mouse brain during postnatal development2011
- Author(s)
  Chizuru Akatsu, Shuji Mizumoto, Tomoyuki Kaneiwa, Marco Maccarana, Anders Malmström, Shuhei Yamada, ○Kazuyuki Sugahara
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-0-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011
- Author(s)
  T.Hashiguchi, S.Mizumoto, Y.Nishimura, J.Tamura, 〇S.Yamada, K.Sugahara
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  QSTATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ヒトヒアルロニダーゼ4とマウスヒアルロニダーゼ4の基質特異性の比較2011
- Author(s)
  山田修平
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  リリックホール・ハイブ長岡(長岡市)
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] 「Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in ?-Thrombomodulin from Human Urine」2011
- Author(s)
  T. Hashiguchi, S. Mizumoto, Y. Nishimura, J. Tamura, S. Yamada, K. Sugahara
- Organizer
  7th International Conference onProteoglycans
- Place of Presentation
  Sydney, Australia
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E 構造の発現低下による転移抑制2011
- Author(s)
  水本秀二, 渡邊基夫, 山田修平, 菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Involvement of HNK-1 Sulfotransferase in the Biosynthesis of Chondroitin Sulfate and the GlcUA(3-O-sulfate)-Gal-Gal-Xyl Tetrasaccharide Found in a-Thrombomodulin from Human Urine2011
- Author(s)
  T. Hashiguchi, S. Mizumoto, Y. Nishimura, J. Tamura, ○S. Yamada, K. Sugahara
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Q STATION (Australia)
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] ルイス肺癌細胞表面上のコンドロイチン硫酸E 構造の発現低下による転移抑制2011
- Author(s)
  渡邊基夫, 水本秀二, 山田修平, ○菅原一幸
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡リリックホール(長岡市)
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Loss-of-function mutations of dermatan 4-O-sulfotransferase-1 cause a new type of Ehlers-Danlos syndrome2011
- Author(s)
  Shuji Mizumoto, Noriko Miyake, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara, and Naomichi Matsumoto
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ、(Poster)
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Determination of amino acid sequences in hyaluronidase-4 responsible for the substrate recognition2011
- Author(s)
  T. Kaneiwa, A. Miyazaki, S. Mizumoto, K. Sugahara, and S. Yamada
- Organizer
  7th International Conference on Proteoglycans
- Place of Presentation
  Sydney, Australia
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Loss-of-function mutations of dermatan 4-O-sulfotransferase-1 cause a new type of Ehlers-Danlos syndrome2011
- Author(s)
  ◯Shuji Mizumoto, Noriko Miyake, Tomoki Kosho, Shuhei Yamada, Kazuyuki Sugahara, and Naomichi Matsumoto
- Organizer
  The 9th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Hokkaido Univ. (Sapporo)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Chondroitin sulfate-specific novel hydrolase in human.2011
- Author(s)
  Shuhei Yamada
- Organizer
  9th International Symposium on Biochemical Roles of Eukaryotic Cell Surface Macromolecules
- Place of Presentation
  Trivandrum, Kerala, India(招待講演)
- Year and Date
  2011-01-28
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] エビ頭部由来へパラン硫酸の構造と機能の研究2011
- Author(s)
  陳建成, 羽磨紀城, Ajaya Kumar Shetty, 小林孝成, 織田浩司, 清木興介, 木村享史, 高橋尚徳, 左一八, 鈴木隆, 鈴木康夫, ○山田修平, 菅原一幸
- Organizer
  日本薬学会北海道支部第136回例会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390016
[Presentation] Structural characterization of heparan sulfate in the Extl3 knockout mice and the pancreatic β-cell specific Extl3 knockout mice.2010
- Author(s)
  Shuhei Yamada
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Structural characterization of heparan sulfate in the Extl3 knockout mice and the pancreatic β-cell specific Extl3 knockout mice.2010
- Author(s)
  Shuhei Yamada
- Organizer
  The 25^<th> International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Involvement of the Hepatocyte Growth Factor Signaling Pathway in the Neuritogenic Activity of Chondroitin Sulfate Derived from Ray Fish Cartilage2010
- Author(s)
  T. Hashiguchi, T. Kobayashi, D. Fongmoon, A. K. Shetty, S. Mizumoto, N. Miyamoto, T. Nakamura, S. Yamada, and K. Sugahara
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Structural characterization of heparan sulfate in the Extl3 knockout mice and the pancreatic β-cell specific Extl3 knockout mice2010
- Author(s)
  T. Kaneiwa, S. Yamada, K. Sugahara, I. Takahashi, N. Noguchi, K. Nata, H. Okamoto, A. Sugawara
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-02
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] コンドロイチン硫酸と芯タンパク質の結合領域に対するモノクローナル抗体の開発とその反応性の解析2010
- Author(s)
  山田修平
- Organizer
  BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] コンドロイチン硫酸と芯タンパク質の結合領域に対するモノクローナル抗体の開発とその反応性の解析2010
- Author(s)
  山田修平
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Identification of a chondroitin sulfate-specific novel hydrolase in human2010
- Author(s)
  T. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
- Organizer
  The 25th International Carbohydrate Symposium (ICS2010)
- Place of Presentation
  Chiba
- Year and Date
  2010-08-05
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] The E-type structure of chondroitin sulfate on tumor cell surfaces is involved in lung and liver metastases.2010
- Author(s)
  Kazuyuki Sugahara, Fuchuan Li, Sengottuvelan Murugan, Basappa, Taishi Hashiguchi, Shuji Mizumoto, Shuhei Yamada, Kayoko Oguri, Minoru Okayama, Kazuki N.Sugahara, Chun Man Lee, Masayuki Miyasaka, Gerdy B.ten Dam, Toin H.van Kuppevelt
- Organizer
  Asian Communications of Glycobiology and Glycotechnology (ACGG)
- Place of Presentation
  Taipei
- Year and Date
  2010-10-27
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Demonstration of chondroitin sulfate-specific hydrolytic activity in human hyaluronidase-42010
- Author(s)
  T. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
- Organizer
  The 8th International Conference on Hyaluronan Sciences
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Identification of a novel chondroitin sulfate hydrolase applicable to neuronal regenerative therapy2010
- Author(s)
  Trivandrum, Kerala, IndiaT. Kaneiwa, S. Mizumoto, K. Sugahara, S. Yamada
- Organizer
  The 8th International Symposium for Future Drug Discovery and Medical Care
- Place of Presentation
  Sapporo
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Extl3 KOマウス及び膵B細胞特異的なExtl3 KOマウスのヘパラン硫酸の分析2009
- Author(s)
  山田修平
- Organizer
  第29回日本糖質学会年会
- Place of Presentation
  高山
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Identification of human hyaluronidase-4 as a novel chondroitin sulfate hydrolase that preferentially cleaves the specific linkage in a highly sulfated sequence.2009
- Author(s)
  Shuhei Yamada
- Organizer
  6th international Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] マウス癌細胞株の肺および肝臓への転移にはコンドロイチン硫酸E様構造が関与する2009
- Author(s)
  山田修平
- Organizer
  第29回日本糖質学会年会
- Place of Presentation
  高山
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Identification and characterization of a novel chondroitin hydrolase in Caenorhabditis elegans2009
- Author(s)
  Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M. Montano, Muneyoshi Otori, Shohei Mitani, and Kazuyuki Sugahara
- Organizer
  6th International Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Cell surface chondroitin sulfate E type structure of mouse tumor cell lines is involved in the experimental metastasis to the lung and liver.2009
- Author(s)
  Shuhei Yamada
- Organizer
  6th International Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Structure and biological activities of heparin-like glycosaminoglycan from shrimp heads2009
- Author(s)
  Jiancheng Chen, Ajaya Kumar Shetty, Takanari Kobayashi, Hiroshi Oda, Kosuke Seiki, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2nd Symposium on Structural Analysis of Biological Macromolecules & 7th Japan-Korea Bilateral Symposium on Biological NMR
- Place of Presentation
  Sapporo
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Cell surface chondroitin sulfate E type structure of mouse tumor cell lines is involved in the experimental metastasis to the lung and liver.2009
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Sengottuvelan Murugan, Fuchuan Li, Basappa, Taishi Hashiguchi, Shuji Mizumoto, Kayoko Oguri, Minoru Okayama, Kazuki N. Sugahara, Chun Man Lee, Masayuki Miyasaka, Gerdy B.ten Dam, Toin H.van Kuppevelt
- Organizer
  6th international Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] Identification and characterization of a novel chondroitin hydrolase in Caenorhabditis elegans2009
- Author(s)
  Tomoyuki Kaneiwa, Shuhei Yamada, Shuji Mizumoto, Adriana M. Montano, Shohei Mitani, and Kazuyuki Sugahara
- Organizer
  2nd Symposium on Structural Analysis of Biological Macromolecules & 7th Japan-Korea Bilateral Symposium on Biological NMR
- Place of Presentation
  Sapporo
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Identification of Human Hyaluronidase-4 as a Novel Chondroitin Sulfate Hydrolase That Preferentially Cleaves the Specific Linkage in a Highly Sulfated Sequence2009
- Author(s)
  Shuhei Yamada, Tomoyuki Kaneiwa, Shuji Mizumoto, and Kazuyuki Sugahara
- Organizer
  6th International Conference on Proteoglycan
- Place of Presentation
  Aix-les-Bains, France
- Year and Date
  2009-09-15
- Data Source
  KAKENHI-PROJECT-21590057
[Presentation] Structural analysis of chondroitin sulfate and dermatan sulfate in heparan sulfate glucuronyl C5-epimerase-deficient mice.2008
- Author(s)
  山田修平
- Organizer
  BMB2008(第81回日本生化学会大会・第31回日本分子生物学会年会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20390019
[Presentation] 組換え体ヒトヒアルロニダーゼ-1および-2の基質特異性の研究2008
- Author(s)
  山田修平
- Organizer
  第28回日本糖質学会年会
- Place of Presentation
  つくば
- Year and Date
  2008-08-20
- Data Source
  KAKENHI-PROJECT-19590052
[Presentation] 線虫Caenorhabditis elegansにおける新規のコンドロイチン加水分解酵素の同定2008
- Author(s)
  山田修平
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590052
[Presentation] 線虫Caenorhabditis elegansにおける新規のコンドロイチン加水分解酵素の同定2008
- Author(s)
  山田修平
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Structural analysis ofchondroitin sulfate and dermatansulfate in heparan sulfate glucuronylC5-epimerase-deficient mice、BMB20082008
- Author(s)
  山田修平
- Organizer
  第81回日本生化学会大会・第31回日本分子生物学会年会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590052
[Presentation] Structural analysis of chondroitin sulfate and dermatan sulfate in henaran sulfate glucuronyl C5-enimerase-deficient mice2008
- Author(s)
  山田修平
- Organizer
  BMB2008(第81回日本生化学会大会・第31回日本分子生物学会年会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590052
[Presentation] Determination of iduronic acid and glucuronic acid in sulfated chondroitin/dermatan hybrid chains by 1H-nuclear magnetic resonance spectroscopy2007
- Author(s)
  Fuchuan Li & Shuhei Yamada & Makiko Sugiura & Kazuyuki Sugahara
- Organizer
  The 127th Japanease Pharmaceutical Symposium
- Place of Presentation
  Toyama
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Determination of iduronic acid and glucuronic acid in sulfated chondroitin/dermatan hybrid chains by 1H-nuclear magnetic resonance spectroscopy2007
- Author(s)
  Fuchuan Li & Shuhei Yamada & Makiko Sugiura & Kazuyuki Sugahara
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] 抗コンドロイチン硫酸D(CS-D)抗体MO-225が認識するCS-E由来のオリゴ糖の構造解析2007
- Author(s)
  山田修平
- Organizer
  第44回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Year and Date
  2007-07-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] The epitope structure recognized by anti-chondroitin sulfate antibodies2007
- Author(s)
  Kazuyuki Sugahara, Sarama S. Deepa, Kittiwan Kalayanamitra, Peraphan Pothacharoen, Prachya Kongtawelert, Yumi Ito, Tadahisa M Ikami, Basappa, Shuhei Yamada, Shigeyuki Fukui, Tim Hardingham, Veronique Blanchard, Franck Chevalier, Anne Imberty, Bas R. Leeflang, Johannis P. Kamerling, Tomohide Hattori, Nobuhiro Hukushima
- Organizer
  The 27^<th> Japanease Carbohydrate Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] サメ軟骨コンドロイチン硫酸由来の八糖の構造解析と抗体のエピトープ解析への応用2007
- Author(s)
  山田修平
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Year and Date
  2007-08-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Chondroitinase-Mediated Degradation of Rare 3-O-Sulfated Glucuronic acid in Functional Oversulfated Chondroitin Sulfate Chains.2007
- Author(s)
  D. Fongmoon, A.K. Shetty, B. Basappa, S. Yamada, M. Sugiura, P. Kongtawelert, and K. Sugahara
- Organizer
  Glycol9 (XIX International Symposium on Glycoconjugates)
- Place of Presentation
  Cairns
- Year and Date
  2007-07-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] コンドロイチン硫酸(CS)/デルマタン硫酸(DS)中のイズロン酸(IdoA)とグルクロン酸(GlcA)の1H NMR解析による定量2007
- Author(s)
  山田修平
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Novel Sulfated Octa- and Decasaccharides from Squid Cartilage Chondroitin Sulfate E: Sequencing and Application for Determination of the Epitope Structure of the Monoclonal Antibody MO-2252007
- Author(s)
  Sarama Sathyaseelan Deepa, Kittiwan Kalayanamitra, Yumi Ito, Prachya Kongtawelert, Shigeyuki Fukui, Shuhei Yamada, Tadahisa Mikami, Kazuyuki Sugahara
- Organizer
  The 27^<th> Japanease Carbohydrate Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] コンドロイチン硫酸(CS)/デルマタン硫酸(DS)中のグルクロン酸(GlcA)とイズロン酸(IdoA)の1H NMR解析による定量2007
- Author(s)
  山田修平
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Structural determination of novel sulfated octasaccharides isolated from chondroitin sulfate of shark cartilage and their application for characterizing monoclonal antibody epitopes2007
- Author(s)
  Sarama S. Deepa, Shuhei Yamada, Shigeyuki Fukui, Kazuyuki Sugahara
- Organizer
  The 27^<th> Japanease Carbohydrate Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2007-08-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Fate and Detection of Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2007
- Author(s)
  Ajaya Kumar Shetty, Duriya Fongmoon, Basappa, Shuhei Yamada, Kazuyuki Sugahara
- Organizer
  The 127th Japanease Pharmaceutical Symposium
- Place of Presentation
  Toyama
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] 単クローン抗体MO-225 が認識するコンドロイチン硫酸E由来のオリゴ糖の構造解析2007
- Author(s)
  山田修平
- Organizer
  第27回日本糖質学会年会
- Place of Presentation
  福岡
- Year and Date
  2007-08-03
- Data Source
  KAKENHI-PROJECT-19590052
[Presentation] Chondroitinase-Mediated Degradation of Rare 3-O-Sulfated Glucuronic Acid in Functional Oversulfated Chondroitin Sulfate Chains2007
- Author(s)
  Ajaya K Shetty, Duriya Fongmoon, Basappa, Shuhei Yamada, Makiko Sugiura, Prachya Kongtawelert and Kazuyuki Sugahara
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] 抗コンドロイチン硫酸D(CS-D)抗体MO-225が認識するCS-E由来のオリゴ糖の構造解析2007
- Author(s)
  山田修平
- Organizer
  第44回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-19590052
[Presentation] Chondroitin Sulfate E Directly Interacts with Herpes Simplex Virus Attachment Glycoprotein C and Exhibits Potent Antiviral Activity2006
- Author(s)
  Satomi Naito, Shuhei Yamada, Kicki Bergefall, Edward Trybala, Maria Johansson, Torn Uyama, Hiroshi Kitagawa, Kazuyuki Sugahara, Tomas Bergstrom
- Organizer
  20^<th> IUBMB International Congress of Biochemistry and Molecular Biology and 11<th> FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Glycosaminoglycans in Hydra magnipapillata2006
- Author(s)
  Shuhei Yamada, Hideto Morimoto, Toshitaka Fujisawa, Kazuyuki Sugahara
- Organizer
  Extracellular Glycomatrix in Health and Disease
- Place of Presentation
  Awaji
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] コンドロイチン硫酸Eは単純ヘルペスウィルスのglycoprotein Cに直接結合し、抗ウィルス活性を発揮する2006
- Author(s)
  山田修平
- Organizer
  第43回日本生化学会北海道支部例会
- Place of Presentation
  札幌
- Year and Date
  2006-11-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Glycosaminoglycans in Hydra magnipapillata.2006
- Author(s)
  山田修平
- Organizer
  Extracellular Glycomatrix in Health and Disease.
- Place of Presentation
  淡路島
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Development of Analytical Method to Detect Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2006
- Author(s)
  Duriya Fongmoon, Ajaya Kumar Shetty, Basappa, Shuhei Yamada, Kazuyuki Sugahara
- Organizer
  XXVIth Japanease Carbohydrate Symposium.
- Place of Presentation
  Sendai
- Year and Date
  2006-08-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] 単純ヘルペスウィルスの感染に関わるコンドロイチン硫酸E2006
- Author(s)
  山田修平
- Organizer
  第26回日本糖質学会年会
- Place of Presentation
  仙台
- Year and Date
  2006-08-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] Development of Analytical Method to Detect Rare 3-O-Sulfated Glucuronic Acid-containing Disaccharides in Various Chondroitin Sulfate Preparations2006
- Author(s)
  Duriya Fongmoon, Ajaya Kumar Shetty, Basappa, Shuhei Yamada, Kazuyuki Sugahara
- Organizer
  The 43th Japanease Biochemistry Symposium (Hokkaido Branch)
- Place of Presentation
  Sapporo
- Year and Date
  2006-11-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390030
[Presentation] コンドロイチン硫酸(CS)/デルマタン硫酸(DS)中のグルクロン酸(GlcA)とイズロン酸(IdoA)の1HNMR解析による定量2004
- Author(s)
  山田修平
- Organizer
  BMB2007(第30回日本分子生物学会年会・第80回日本生化学会大会合同大会)
- Place of Presentation
  横浜
- Year and Date
  2004-12-12
- Data Source
  KAKENHI-PROJECT-19590052
[Presentation] Novel highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: Insights into the sugar sequences involved in brain development
- Author(s)
  ○Shuji Mizumoto, Saori Murakoshi, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, Shigeyuki Fuku5, Prachya Kongtawelert, Shuhei Yamada, and Kazuyuki Sugahara
- Organizer
  2012年度　包括型脳科学研究推進支援ネットワーク・夏のワークショップ
- Place of Presentation
  仙台国際センター(仙台)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] サメヒレ軟骨コンドロイチン硫酸由来の新規な六糖配列の単離
- Author(s)
  ◯水本秀二, 村越早織, Kittiwan Kalayanamitra, Sarama Sathyaseelan Deepa, 福井成行, Prachya Kongtawelert, 山田修平, 菅原一幸
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-23790066
[Presentation] Novel CS-E-Binding Proteins in Mouse Brain That May Be Involved in the Neurite Outgrowth Promoting Mechanism through Chondroitin Sulfate E-Type
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, and Kosei Takeuchi
- Organizer
  Gordon Research Conference on Proteoglycans 2014
- Place of Presentation
  Andover, USA
- Year and Date
  2014-07-07 – 2014-07-10
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Expression Analysis of Hyaluronidases in the Mouse Brain during Development
- Author(s)
  Yuka Oiwa, Shuji Mizumoto, Ryoji Kojima, Tadashi Nagamatsu, Shuhei Yamada
- Organizer
  Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate Research “Glycans in Neuroscience”
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2014-11-16 – 2014-11-18
- Data Source
  KAKENHI-PROJECT-24590071
[Presentation] Novel CS-E-Binding Proteins in Mouse Brain That May Be Involved in the Neurite Outgrowth Promoting Mechanism through Chondroitin Sulfate E-Type
- Author(s)
  Kazuyuki Sugahara, Shuji Mizumoto, Yusuke Yoshikawa, Shuhei Yamada, and Kosei Takeuchi
- Organizer
  Gordon Research Conference on Proteoglycans 2014
- Place of Presentation
  Andover, USA
- Year and Date
  2014-07-07 – 2014-07-10
- Data Source
  KAKENHI-PUBLICLY-26110719
[Presentation] Mass preparation of oligosaccharides with intestinal absorption capacity by hydrolysis of chondroitin sulfate polysaccharides with subcritical water microreaction system
- Author(s)
  Kazuyuki Sugahara, Shuhei Yamada, Shuji Mizumoto, Keiichiro Matsushima, Haruo Ura, and Nobuyuki Miyamoto
- Organizer
  The 13th International Conference on Functional and Medical Foods with Bioactive Compounds: Science and Practical Applications”
- Place of Presentation
  The Kyoto Prefectural University of Medicine (京都)
- Data Source
  KAKENHI-PROJECT-23390016

1. SUGAHARA Kazuyuki (60154449)

# of Collaborated Projects: 21 results

# of Collaborated Products: 158 results
2. MIZUMOTO Shuji (40443973)

# of Collaborated Projects: 8 results

# of Collaborated Products: 132 results
3. KITAGAWA Hiroshi (40221915)

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# of Collaborated Products: 1 results
4. MIKAMI Tadahisa (20330425)

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5. MIYAKE Noriko (40523494)

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6. KOSHO Tomoki (90276311)

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7. IKEGAWA Shiro (30272496)

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8. MATSUMOTO Naomichi (80325638)

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9. ASANO Masahide (50251450)

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10. YOSHIZAWA TAKAHIRO (40713392)

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11. Janecke Andreas

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29. YOSHIDA Keiichi

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30. NAKAJIMA Motowo

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31. BASAPPA

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33. STEFAN Mundlos

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34. LIHADH Al-gazali

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35. KATRIN Hoffmann

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38. LI Fuchuan

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40. Kennerknecht Ingo

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41. Vodopiutz Julia

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42. Kornak Uwe

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43. TAIRA Masanori

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44. TAKADA Ritsuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. TANI Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. GUO long

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. YOKOYAMA Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
48. SUGAWARA akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
49. HAKODA Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. ITO ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
51. WATANABE Kota

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
52. 高田慎治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 三井優輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 王錚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 高木清司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 佐藤博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 郭竜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 藤倉大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamada Shuhei 山田 修平

YAMADA Shuhei 山田 修平

Research Projects

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Integrated understanding of dermatan sulfate through uncovering pathophysiology of musculocontractural Ehlers-Danlos syndromeOngoing

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Elucidation of the novel functions of EXTL3 involved in the biosynthesis of heparan sulfate in brains and T cellsPrincipal InvestigatorOngoing

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シンデカン４ノックアウトマウスにおけるインスリン分泌機能の解析Ongoing

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Function as well as regulation on expression of a novel hyaluronidase in cancer and inflammationPrincipal Investigator

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脳におけるコンドロイチン硫酸およびヒアルロン酸の代謝分解機構の解明Principal Investigator

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Structural and functional studies on the novel hyaluronidase trying for its clinical applicationPrincipal Investigator

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Identification of endo-type chondroitin sulfate hydrolases applicable to neuronal regenerative therapyPrincipal Investigator

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Study on the structure and functions of sulfated glycosaminoglycans involved in the development or treatment of liver diseases.Principal Investigator

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Yamada Shuhei 山田修平

YAMADA Shuhei 山田修平