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Akimaru Hiroshi  秋丸 裕司

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秋丸 裕司  アキマル ヒロシ

AKIMARU Hiroshi  秋丸 裕司

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Researcher Number 70241247
Affiliation (Current) 2022: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所 難治性疾患研究開発・支援センター, 研究調整専門員
Affiliation (based on the past Project Information) *help 2014: 公益財団法人先端医療振興財団, その他部局等, 研究員
2013: 公益財団法人先端医療振興財団, 先端医療センター研究所再生医療研究部血管再生研究グループ, 客員研究員
2003: 独立行政法人理化学研究所, 分子遺伝学研究室, 先任研究員
1999 – 2002: Laboratory of Moleular and Genetics, Senior Research Schientist, 分子遺伝学研究室, 先任研究員
1997 – 1998: 理化学研究所, 分子遺伝学研究室, 研究員
1992 – 1994: 理化学研究所, 分子遺伝学研究室, 研究員
Review Section/Research Field
Principal Investigator
Biological Sciences / Regenerative medicine / Developmental biology
Except Principal Investigator
General medical chemistry
Keywords
Principal Investigator
ショウジョウバエ / 形態形成 / Hedgehog / モザイク解析 / JNK / RNAi / Cubitus interruptus / 転写因子 / 分子遺伝学 / 翅成虫原基 … More / Hedghog / ATF-2 / p38 / dmyb / dmi-2 / CREB binding protein / 発生 / CREB-binding protein / co-activator / Moonrat / CBP / Ci / タンパク質分解 / ユビキチネーション / SAPK / dATF-2 / dsRNA / MEKK / Hedgehoge / ユビキチン / lysosome / MVB / 成虫原基 / endosome / 免疫電顕 / ubiquitination / multi vesicular body / cubitus interruptus / 蛋白質分解 / apoptosis / osmotic stress / ヒトiPS / 血管内皮前駆細胞 / EPC / シングルセルqPCR / single cell qPCR / 複眼成虫原基 / 細胞周期 / Myb / Mi-2 / 複眼 / Drosophila / transcription factor / eye imaginal disc / cell cycle / mosaic analysis … More
Except Principal Investigator
CBP / ショウジョウバエ / Myb / コアクティベーター / Ski / 転写制御因子 / 発生 / 変異体 / 劣性致死突然変異体 / 転写仲介因子 / ショウジョウバエ変異体 / マウス変異体 / コアクティベータ- / 仲介因子 / 転写制御 / 形態形成 / transcriptional mediators / coactivator / Drosophila mutant / mouse mutant / コリプレッサー / ヒストンアセチル化 / C-activator / Co-repressor / Histone acetylation Less
  • Research Projects

    (15 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (12 People)
  •  ヒトiPS 由来血管内皮前駆細胞の機能評価の構築Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Regenerative medicine
    • Research Institution
      Foundation for Biomedical Research and Innovation
  •  アポトーシスにおけるショウジョウバエJNK/p38とATF-2の遺伝学的機能解析Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  RNAiを用いたショウジョウバエATF-2のアポトーシスへの機能解析Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  ショウジョウバエHh/Ci伝達系に関与する遺伝子の単離と機能解析Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  ショウジョウバエHh/Ci伝達系に関与する遺伝子の単離と機能解析Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  RNAiを用いたショウジョウバエATF-2のアポートシスへの機能解析Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The Institute of Physical and Chemical Research
  •  ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Research on Gene Expression Network via histone acetylation

    • Principal Investigator
      ISHII Shunsuke
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General medical chemistry
    • Research Institution
      The Institute of Physical and Chemical Research (RIKEN)
  •  ショウジョウバエHh/dCBP/Ci伝達系に関与する遺伝子の単離同定Principal Investigator

    • Principal Investigator
      秋丸 裕司
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Functional analysis of the D-myb gene in DrosophilaPrincipal Investigator

    • Principal Investigator
      AKIMARU Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      The Institute of Physical and Chemical Research, RIKEN
  •  Research on Gene Expression Network via Coactivator CBP

    • Principal Investigator
      ISHII Shunsuke
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      The Institute of Physical and Chemical Research (RIKEN)
  •  ショウジョウバエMyb,CRE結合蛋白質の遺伝学的解析

    • Principal Investigator
      石井 俊輔
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  細胞増殖を制御する転写因子の遺伝学的解析

    • Principal Investigator
      石井 俊輔
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research
  •  細胞増殖を制御する転写因子の遺伝学的解析

    • Principal Investigator
      ISHII Shunsuke
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The Institute of Physical and Chemical Research

All 2015 2014 2013

All Journal Article Book

  • [Book] 図説 分子病態学 改訂5版(6.細胞の増殖・分化と再生医学)2014

    • Author(s)
      秋丸裕司 浅原孝之(一瀬白帝 編著)
    • Total Pages
      408
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-25505009
  • [Journal Article] SDF-1/CXCR4 axis in Tie2-lineage cells including endothelial progenitor cells contributes to bone fracture healing.2015

    • Author(s)
      Kawakami Y, Ii M, Matsumoto T, Kuroda R, Kuroda T, Kwon SM, Kawamoto A, Akimaru H, Mifune Y, Shoji T, Fukui T, Kurosaka M, Asahara T.
    • Journal Title

      J Bone Miner Res

      Volume: 30(1) Pages: 95-105

    • DOI

      10.1002/jbmr.2318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25505009, KAKENHI-PROJECT-25462331
  • [Journal Article] Sonic Hedgehog signaling regulates vascular differentiation and function in human CD34 positive cells: Vasculogenic CD34+ cells with Sonic Hedgehog.2015

    • Author(s)
      Kanaya K, Masaaki I, Okazaki T, Nakamura T, Horii-Komatsu M, Alev C, Akimaru H, Kawamoto A, Akashi H, Tanaka H, Asahi M, Asahara T.
    • Journal Title

      Stem Cell Res.

      Volume: 14(2) Pages: 165-176

    • DOI

      10.1016/j.scr.2015.01.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460397, KAKENHI-PROJECT-25505009
  • [Journal Article] Dextran induces differentiation of circulating endothelial progenitor cells.2014

    • Author(s)
      S. Obi, H. Masuda, H. Akimaru, T. Shizuno, K. Yamamoto, J. Ando, and T. Asahara
    • Journal Title

      Physiol Rep

      Volume: 2

    • DOI

      10.1002/phy2.261

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25282128, KAKENHI-PROJECT-25461091, KAKENHI-PROJECT-25505009, KAKENHI-PROJECT-26242043
  • [Journal Article] Vasculogenic Conditioning of Peripheral Blood Mononuclear Cells Promotes Endothelial Progenitor Cell Expansion and Phenotype Transition of Anti‐Inflammatory Macrophage and T Lymphocyte to Cells With Regenerative Potential2014

    • Author(s)
      H. Masuda, R. Tanaka, S. Fujimura, M. Ishikawa, H. Akimaru, T. Shizuno, A. Sato, Y. Okada, Y. Iida, J. Itoh, Y. Itoh, H. Kamiguchi, A. Kawamoto, T. Asahara.
    • Journal Title

      J Am Heart Assoc

      Volume: 3

    • DOI

      10.1161/jaha.113.000743

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461091, KAKENHI-PROJECT-25505009, KAKENHI-PROJECT-26461320
  • [Journal Article] Superior Potential of CD34-Positive Cells Compared to Total Mononuclear Cells for Healing of Nonunion Following Bone Fracture.2014

    • Author(s)
      Fukui T, Mifune Y, Matsumoto T, Shoji T, Kawakami Y, Kawamoto A, Ii M, Akimaru H, Kuroda T, Horii M, Yokoyama A, Alev C, Kuroda R, Kurosaka M, Asahara T.
    • Journal Title

      Cell Transplant

      Volume: May 2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25505009
  • [Journal Article] Human cardiac stem cells with reduced notch signaling show enhanced therapeutic potential in a rat acute infarction model.2013

    • Author(s)
      Matsuda T, Miyagawa S, Fukushima S, Kitagawa-Sakakida S, Akimaru H, Horii-Komatsu M, Kawamoto A, Saito A, Asahara T, Sawa Y.
    • Journal Title

      Circ J

      Volume: 78(1) Pages: 222-231

    • NAID

      130003382177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25505009
  • [Journal Article] A Small Interfering RNA Targeting Lnk Accelerates Bone Fracture Healing with Early Neovascularization.2013

    • Author(s)
      Kawakami Y, Ii M, Matsumoto T, Kawamoto A, Kuroda R, Akimaru H, Mifune Y, Shoji T, Fukui T, Asahi M, Kurosaka M, Asahara T.
    • Journal Title

      Lab Invest

      Volume: 93 Pages: 1036-1053

    • DOI

      10.1038/labinvest.2013.93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460397, KAKENHI-PROJECT-25462331, KAKENHI-PROJECT-25505009
  • 1.  ISHII Shunsuke (00124785)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  MAEKAWA Toshio (90201764)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  浅原 孝之 (20246200)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 4.  川本 篤彦 (00275330)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  MASUDA Haruchika
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  ASAHI Michio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  Ii Masaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  KURODA Ryosuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  KUROSAKA Masahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 10.  MATSUMOTO Tomiyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  安藤 譲二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  山本 希美子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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