HORI Toshiyuki 堀利行

… Alternative Names

Researcher Number	70243102
Other IDs
External Links
Affiliation (Current)	2022: 立命館大学, 生命科学部, 教授
Affiliation (based on the past Project Information) *help	2015: 立命館大学, 生命科学部, 教授 2008 – 2013: Ritsumeikan University, 生命科学部, 教授 2009: 京都大学, 医学研究科, 講師 2005 – 2007: 京都大学, 医学研究科, 講師 1998 – 2003: 京都大学, 医学研究科, 講師 … More
Review Section/Research Field	Principal Investigator Hematology / Hematology / Tumor biology / 内科学一般 / アレルギー Except Principal Investigator Hematology / Biological Sciences / 内科学一般 / General medical chemistry / General physiology
Keywords	Principal Investigator OX40 / gp34 / T細胞 / 癌 / ATL / RASSF / CXCR-4 / HIV-1 / OX40 ligand / Bone marrow transplantation … More Except Principal Investigator OX40 / gp34 / ATL / 樹状細胞 / ADF / thioredoxin / Thioredoxin / 転写調節因子 / シグナル伝達 / Redox regulation / HTLV-I / IL-2 / AP-1 / gP34 / NF-kB / HIV-1 / TRAF / endothelial cell / GVHD / GVL / ONO-4007 / OX40 ligand / 肝移植 / FK506 / B Cell lymphoma / Epstein-Barr virus / soluble CD23 / Interleukin-10 / 細胞・免疫療法 / 同種造血幹細胞移植 / 腫瘍関連抗原 / NK細胞 / T細胞 / 細胞・免疫治療 / redox regnlation / NFKB / 細胞活性化 / Oxygen Stress / NFκB / Oxygen stress / redox regulation / NFkappaB / transcriptional factor / cell activation / oxygen stress / signal transduction / 造腫瘍性 / SCIDマウス / 細胞接着分子 / Tumorigenicity / SCID mouse / Adhesion molecule / レドックス制御 / 抗ガン剤 / アポトーシス / 虚血 / レドックス / 核タンパク質 / 細胞死 / ヒトthioredoxin / phagocyte oxidase / シクロヘキシミド / TGF-β / Yeast two hybrid / cis-element / Jun, Fos / Ref-1 / direct interaction / CDDP / transcription factor / Anti-cancer drug / Apoptosis / Ischemia / 細胞接着 / NF-KB / cell adhesion / 宿主因子 / 病態 / 免疫 / 制御 / ケモカイン / ケモカイン受容体 / エイズ / HIV複製 / コレセプター / 抗HIV免疫 / 抗HIV剤 / 薬剤耐性 / Host Factors / Pathophysiology / Immune response / AIDS Control / Chemokine / Chemokine Receptor / NF-κB / c-jun / 共刺激 / 造血器腫瘍 / 自然免疫 / 腫瘍ワクチン / 抗腫瘍免疫 / アジュバンド / OX40 リガンド / OX40 ligand(gp34) / ドラッグデリバリーシステム / innate immunity / fumor vaccine / anti-fumor immunity / インスリンシグナル / 寿命制御 / ユビキチン / ユビキチン化 Less

The elucidation of the mechanism of novel insulin signal via TRIM/RBCC E3 ligase
- Principal Investigator
  
  Inoue Hideki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
  General physiology
- Research Institution
  Kanagawa Institute of Technology
Search for RASSF-interacting molecules using C. elegansPrincipal Investigator
- Principal Investigator
  
  HORI Toshiyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Ritsumeikan University
Molecular pathogenesis of abnormal kpm (Lats2) expression in leukemiaPrincipal Investigator
- Principal Investigator
  
  HORI Toshiyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Ritsumeikan University
Development of effective hematopoietic stem cell transplantation/cellular immunotherapy for adult T-cell leukemia
- Principal Investigator
  
  KADOWAKI Norimitsu, 内山卓
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Involvement of guanylyl cyclase signals of dendritic cells in allergic statePrincipal Investigator
- Principal Investigator
  
  HORI Toshiyuki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  アレルギー
- Research Institution
  Kyoto Unversity
Basic Research for AIDS control
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  2002
- Research Category
  
  特定領域研究
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Immunotherapy of hematological melignancies based on activation of innate immunity and costimulation through OX40/OX40L
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Characterization of OX40+ T cells detected in patients with GVHD after hematopoietic stem cell transplantationPrincipal Investigator
- Principal Investigator
  
  HORI Toshiyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  KYOTO UNIVERSITY
Development of novel therapies of hematologic malignancies based on the functional modulation of the OX40/gp34 system
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Analysis of signal transduction of OX40/gp34 and its role in pathogenesis of hematologic diseases
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
ATL細胞に発現するT細胞活性化抗原OX40の病態生理学的意義Principal Investigator
- Principal Investigator
  
  堀利行
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Immunohematologic studies on the SDF-1/CXCR-4 system with monoclonal antibod.Principal Investigator
- Principal Investigator
  
  HORI Toshiyuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
T細胞の癌化に伴って発現誘導される細胞膜蛋白の構造と機能Principal Investigator
- Principal Investigator
  
  堀利行
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
ROLR OF OX40 IN IN VIVO CELL GROWTH AND ORGAN INFILTRATION OF ATL CELLS
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
T細胞腫瘍のin vivo増殖に関与する新しい細胞膜分子の同定Principal Investigator
- Principal Investigator
  
  堀利行
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Molecular analysis of redox regulation in infectious disease and immune disease
- Principal Investigator
  
  YODOI Junji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  KYOTO UNIVERSITY
Studies on the mechanism of cell growth of ATL cells
- Principal Investigator
  
  UCHIYAMA Takashi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  KYOTO UNIVERSITY
Scid miceを用いたB細胞リンパ腫の発症機構の解析と治療法の開発
- Principal Investigator
  
  稲本俊
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Studies on activation mechanism in the viral diseases
- Principal Investigator
  
  YODAI Junji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Institute For Virus Research, Kyoto University

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] C. elegans Rassf homolog, rasf-1, is functionally associated with rab-39 Rab GTPase in oxidative stress response2013
- Author(s)
  Motohiko Takenaka, Hideki Inoue, Atsushi Takeshima, Tomonori Kakura and Toshiyuki Hori
- Journal Title
  
  Genes to Cells
  
  Volume: 18 Pages: 203-210
- DOI
  10.1111/gtc.12028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501272
[Journal Article] TSLP fosters human breast cancer tumor development by promoting type 2 inflammation.2011
- Author(s)
  Alexander Pedroza-Gonzalez1, Kangling Xu, Te-Chia Wu, Caroline Aspord, Sasha Tindle, Florentina Marches, Michael Gallegos, Elizabeth C. Burton, Daniel Savino, Toshiyuki Hori, Yuetsu Tanaka, Sandra Zurawski, Gerard Zurawski, Laura Bover, Yong-Jun Liu, Jacques, Banchereau, A.Karolina Palucka
- Journal Title
  
  J.Exp.Med. 208
  
  Pages: 479-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591122
[Journal Article] The CD70-CD27 interaction during the stimulation withdendritic cells promotes naive CD4^+ T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans.2009
- Author(s)
  Mutsumi Hashimoto, Toshio Kitawaki, Norimitsu Kadowaki, Satoshi Iwata, Chikao Morimoto, Toshiyuki Hori, Takashi Uchiyama
- Journal Title
  
  Int.Immunol. 21
  
  Pages: 891-904
- NAID
  10025387511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591122
[Journal Article] Mycophenolate mofetil combined with tacrolimus and minidose methotrexate after unrelated donor bone marrow transplantation with reduced-intensity conditioning.2009
- Author(s)
  Mizumoto C, Ichinohe T, Ishikawa T, Kadowaki N, Imada K, Hishizawa M, Hori T, Uchiyama T, 他6名.
- Journal Title
  
  Int J Hematol 89
  
  Pages: 538-545
- NAID
  10025161531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Human plasmacytoid dendritic cells express an atrial natriuretic peptide receptor, guanylyl cyclase-A.2009
- Author(s)
  Rimpei Morita, Tomoko Fujita, Takashi Uchiyama, Toshiyuki Hori
- Journal Title
  
  Microbiol.Immunol. 53
  
  Pages: 403-411
- NAID
  10027686984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591122
[Journal Article] Mycophenolate mofetil combined with tacrolimus and minidose methotrexate after unrelated donor bone marrow transplantation with reduced-intensity conditioning.2009
- Author(s)
  Chisaki Mizumoto, Junya Kanda, Tatsuo Ichinohe, Takayuki Ishikawa, Masashi Matsui, Norimitsu Kadowaki, Tadakazu Kondo, Kazunori, Imada, Masakatsu Hishizawa, Hiroshi Kawabata, Momoko Nishikori, Kouhei Yamashita, Akifumi Takaori-Kondo, Toshiyuki Hori, Takashi Uchiyama
- Journal Title
  
  Int.J.Hematol. 89
  
  Pages: 538-545
- NAID
  10025161531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591122
[Journal Article] Growth and differentiation advantages of CD4+OX40+T cells from allogeneic hematopoietic stem cell transplantation recipients2008
- Author(s)
  T. Shindo, T. Ishikawa, A. Fukunaga, T. Hori, et al.
- Journal Title
  
  Biol. Blood Marrow Transplant. 14
  
  Pages: 268-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591122
[Journal Article] Kpm/Lats2 is linked to chemosensitivity of leukemic cellsthrough the stabilization of p73.2008
- Author(s)
  Masahiro Kawahara, Toshiyuki Hori, Tsutomu Oka, Marius Sudol, Takashi Uchiyama
- Journal Title
  
  Blood 112
  
  Pages: 3856-3866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591122
[Journal Article] Growth and differentiation advantages of CD4^+ OX406+ T cells from allogeneic hematopoietic stem cell transplantation recipients.2008
- Author(s)
  Takero Shindo, Takakyuki Ishikawa, Akiko Fukunaga, Toshiyuki Hori, Takashi Uchiyama
- Journal Title
  
  Biol.Blood Marrow Tr. 14
  
  Pages: 268-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591122
[Journal Article] Kpm/Lats2 is linked to chemo-sensitivity of leukemic cells through the stabilization of p732008
- Author(s)
  T. Kawahara, T. Hori, et al.
- Journal Title
  
  Blood 112
  
  Pages: 3856-3866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591122
[Journal Article] Growth and differentiation advantages of CD4+ OX40+ T cells from allogeneic hematopoietic stem cell transplantation recipients.2008
- Author(s)
  Shindo T, Ishikawa T, Fukunaga A, Hori T, Uchiyama T.
- Journal Title
  
  Biol Blood Marrow Transplant 14
  
  Pages: 268-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Cyclin-dependent kinase-like 5 is a novel target of immunotherapy in adult T cell leukemia.2007
- Author(s)
  Kawahara Masahiro
- Journal Title
  
  J. Immunother. 30
  
  Pages: 499-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Involvement of 0X40 ligand+ mast cells in chronic GVHD after allogeneic hematopoietic stem cell transplantation.2007
- Author(s)
  Ai Kotani, Toshiyuki Hori, Tomoko Fujita, Naotomo Kambe, Yumi Matsumura., Takayuki Ishikawa., Yoshiki Miyachi, Kenichi Nagai, Yuetsu Tanaka, Takashi Uchiyama.
- Journal Title
  
  Bone Marrow Transpl. 39 (6)
  
  Pages: 373-375
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Cyclin-dependent kinase-like 5 is a novel target of immunotherapy in adult T cell leukemia.2007
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T.
- Journal Title
  
  J Immunother 30
  
  Pages: 499-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Involvement of 0X40 ligand+ mast cells in chronic GVHD after allogeneic hematopoietic stem cell transplantation.2007
- Author(s)
  Kotani A, Hori T, Fujita T, Kambe N, Matsumura Y, Ishikawa T, Miyachi Y, Nagai K, Tanaka Y, Uchiyama T
- Journal Title
  
  Bone Marrow Transpl. 39 (6)
  
  Pages: 373-375
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Involvement of OX40 ligand+ mast cells in chronic GVHD after allogeneic hematopoietic stem cell transplantation.2007
- Author(s)
  Ai Kotani, Toshiyuki Hori, Tomoko Fujita, Naotomo Kambe, et al.
- Journal Title
  
  Bone Marrow Transpl. 39 (6)
  
  Pages: 373-375
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Cyclin-dependent kinase-like 5 is a novel target of immunotherapy in adult T cell leukemia.2007
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T
- Journal Title
  
  J.Immunother. (in press)
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Type I interferons attenuate T cell activating functions of human mast cells by decreasing TNF-α production and OX40 ligand expression while increasing IL-10 production.2006
- Author(s)
  Tomoko Fujita, Naotomo Kambe, Takashi Uchiyama, Toshiyuki Hori
- Journal Title
  
  J. Clin. Immunol. 26 (6)
  
  Pages: 512-518
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Functional characterization of 0X40 expressed on human CD8+ T cells.2006
- Author(s)
  Tomoko Fujita, Naoya Ukyo, Toshiyuki Hori, Takashi Uchiyama
- Journal Title
  
  mmunol. Lett. 106 (1)
  
  Pages: 27-33
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Type I interferons attenuate T cell activating functions of human mast cells by decreasing TNF-alpha production and 0X40 ligand expression while increasing IL-10 production.2006
- Author(s)
  Tomoko Fujita, Naotomo Kambe, Takashi Uchiyama, Toshiyuki Hori
- Journal Title
  
  J. Clin. Immunol. 26 (6)
  
  Pages: 512-518
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells.2006
- Author(s)
  Toshio Kitawaki, Norimitsu Kadowaki, Naoshi Sugimoto, Naotomo Kambe, Toshiyuki Hori, et al.
- Journal Title
  
  Int. Immunol. 18 (12)
  
  Pages: 1789-1799
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Roles of OX40 in the pathogenesis and control of diseases.2006
- Author(s)
  Toshiyuki Hori
- Journal Title
  
  Int. J. Hematol. 83 (1)
  
  Pages: 17-22
- NAID
  10017147715
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Roles of OX40 in the pathogenesis and control of diseases.2006
- Author(s)
  Toshiyuki Hori.
- Journal Title
  
  Int. J. Hematol. 83 (1)
  
  Pages: 17-22
- NAID
  10017147715
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Type I interferons attenuate T cell activating functions of human mast cells by decreasing TNF-α production and OX40 ligand expression while increasing IL-10 production.2006
- Author(s)
  Tomoko Fujita, Naotomo Kambe, Takashi Uchiyama, Toshiyuki Hori.
- Journal Title
  
  J. Clin. Immunol. 26 (6)
  
  Pages: 512-518
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells.2006
- Author(s)
  Toshio Kitawaki, Norimitsu Kadowaki, Naoshi Sugimoto, Naotomo Kambe, Toshiyuki Hori, Yoshiki Miyachi, Tatsutoshi Nakahata, Takashi Uchiyama
- Journal Title
  
  Int. Immunol. 18 (12)
  
  Pages: 1789-1799
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Identification of HLA class I-restricted tumor-associated antigens in adult T cell leukemia cells by mass spectrometric analysis.2006
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T.
- Journal Title
  
  Exp Hematol 34
  
  Pages: 512-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Identification of HLA class I-restricted tumor-associated antigens in adult T cell leukemia cells by mass spectrometric analysis.2006
- Author(s)
  Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T
- Journal Title
  
  Exp.Hematol. 34 (11)
  
  Pages: 512-518
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Serological identification of adult T-cell leukaemia (ATL)-associated antigens.2005
- Author(s)
  Hishizawa M, Imada K, Sakai T, Ueda M, Hori T, Uchiyama T
- Journal Title
  
  Br J Haematol 130
  
  Pages: 382-390
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Nitric oxide inhibits IFN-α production of human plasmacytoid dendritic cells partly via a guanosine 3',5'-cyclic monophosphate-dependent pathway2005
- Author(s)
  Rimpei Morita, Takashi Uchiyama, Toshiyuki Hori.
- Journal Title
  
  J. Immunol. 175 (2)
  
  Pages: 806-812
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Phenotypic an functional relationship-between adult T cell leukemia cells and regulatory T cells.2005
- Author(s)
  Yasushi Matsubara, Toshiyuki Hori, Rimpei Morita, Shimon Sakaguchi, Takashi Uchiyama
- Journal Title
  
  Leukemia 19
  
  Pages: 482-483
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] TSLP-activated dendritic cells induce inflammatory TH2 response through OX40-ligand : a master switch of interleukin-10 and tumor necrosis factor-a.2005
- Author(s)
  Tomoki Ito, Yui-Hsi Wang, Omar Duramad, Toshiyuki Hori, et al.
- Journal Title
  
  J. Exp. Med. 202 (9)
  
  Pages: 1213-1223
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Introduction of OX40 ligand into lymphoma cells elicits anti-lymphoma immunity in vivo.2005
- Author(s)
  Hitomi Kaneko, Toshiyuki Hori, Soshi Yanagita, Norimitsu Kadowaki, Takashi Uchiyama
- Journal Title
  
  Exp.Hematol. 33
  
  Pages: 336-343
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Nitric oxide inhibits IFN-α production of human plasmacytoid dendritic cells partly via a guanosine 3',5'-cyclic monophosphate-dependent pathway.2005
- Author(s)
  Rimpei Morita, Takashi Uchiyama, Toshiyuki Hori
- Journal Title
  
  J.Immunol. 175
  
  Pages: 806-812
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA2005
- Author(s)
  Javier Mestas, Steve P.Crampton, Toshiyuki Hori, Christopher C.W.Hughes
- Journal Title
  
  Int.Immunol. 17
  
  Pages: 737-747
- NAID
  10019358666
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Introduction of OX40 ligand into lymphoma cells elicits anti-lymphoma immunity in vivo.2005
- Author(s)
  Kaneko H, Hori T Yanagita S, Kadowaki N, Uchiyama T
- Journal Title
  
  Exp Hematol 33
  
  Pages: 336-343
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] TSLP-activated dendritic cells induce inflammatory response through OX40-ligand : a master switch of interleukin-10 and tumor necrosis factor-α2005
- Author(s)
  Tomoki Ito, Yui-Hsri Wang, Omar Duramad, Toshiyuki Hori, Guy J Delespesse, Norihiko Watanabe, F.Xiao-Feng Qin, Zhengbin Yao, Wei Cao, Yong-Jun Liu
- Journal Title
  
  J.Exp.Med. 202
  
  Pages: 1213-1223
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] TSLP-activated dendritic cells induce inflammatory TH2 response through OX40-ligand : a master switch of interleukin-10 and tumor necrosis factor-α.2005
- Author(s)
  Tomoki Ito, Yui-Hsi Wang, Omar Duramad, Toshiyuki Hori, et al.
- Journal Title
  
  J. Exp. Med. 202 (9)
  
  Pages: 1213-1223
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Phenotypic and functional relationship between adult T cell leukemia cells and regulatory T cells.2005
- Author(s)
  Matsubara Y, Hori T, Morita R, Sakaguchi S, Uchiyama T.
- Journal Title
  
  Leukemia 19
  
  Pages: 482-483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Serological identification of adult T-cell leukaemia(ATL)-associated antigens.2005
- Author(s)
  Masakatsu-Hishizawa, Kazunori Imada, Tomomi Sakai, Maki Ueda, Toshiyuki Hori, Takashi Uchiyama
- Journal Title
  
  Br.J.Haematol. 130
  
  Pages: 382-390
- Data Source
  KAKENHI-PROJECT-17607006
[Journal Article] Phenotypic and functional relationship between adult T cell leukemia cells and regulatory T cells.2005
- Author(s)
  Matsubara Y, Hori T, Morita R, Sakaguchi S, Uchiyama T
- Journal Title
  
  Leukemia 19
  
  Pages: 482-483
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Serological identification of adult T-cell leukaemia (ATL)-associated antigens.2005
- Author(s)
  Hishizawa M, Imada K, Sakai T, Ueda M, Hori T, Uchiyama T.
- Journal Title
  
  Br J Haematol 130
  
  Pages: 382-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016034
[Journal Article] Nitric oxide inhibits IFN-α production of human plasmacytoid dendritic cells partly via a guanosine 3',5'-cyclic monophosphate-dependent pathway
- Author(s)
  Rimpei Morita, Takashi Uchiyama, Toshiyuki Hori
- Journal Title
  
  J. Immunol.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17607006
[Presentation] Tet-On 発現誘導システムを用いたTRIM3 の機能解析2013
- Author(s)
  道上康平、竹島淳史、渡辺大悟、井上英樹、堀利行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] 線虫と哺乳類におけるRassf とRif1 の相互作用2013
- Author(s)
  鎌田顕志、井上英樹、今田遼介、竹中元彦、堀利行
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-10-03
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] C. elegans のRif1 相同体F11E6.6 (rif-1)の同定と特性化2013
- Author(s)
  鎌田顕志、井上英樹、今田遼介、竹中元彦、堀利行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM3, a TRIM/RBCC protein, interacts with LATS2 and regulates the downstream signals of the Hippo pathway2013
- Author(s)
  Hideki Inoue, Tomonori Kakura, Atsushi Takeshima, Kouhei Michiue, Daigo Watanabe, Toshiyuki Hori
- Organizer
  Keystone Symposia "The Hippo Tumor Suppressor Network"
- Place of Presentation
  Monterey, USA
- Year and Date
  2013-05-20
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM/RBCC E3 リガーゼNHL-1/TRIM3はDAF-16/FOXO タンパク質の安定化を介してインスリンシグナルを制御する2013
- Author(s)
  井上英樹、香座知典、竹島淳史、堀利行
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-10-03
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM3によるLATS2 タンパク質安定化の分子機構2013
- Author(s)
  渡辺大悟、道上康平、竹島淳史、大島遥香、前田木実、井上英樹、堀利行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] LATS2とE3 プロテインリガーゼPIAS2 の相互作用2013
- Author(s)
  安田有、渡辺大悟、安藤有美、大賀美咲、香座知典、井上英樹、堀利行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM/RBCC protein, TRIM3, regulates localization of Yes-associated protein 1 (YAP1)2012
- Author(s)
  井上英樹、香座知典、竹島淳史、竹中元彦、堀利行
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM/RBCC E3 リガーゼ、NHL-1/TRIM3はDAF-16/FOXO タンパク質の安定化を介してinsulin/IGF シグナルを制御する2012
- Author(s)
  井上英樹、香座知典、竹島淳史、堀利行
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM/RBCC タンパク質TRIM3 はYAP の局在転移を介してHippo 経路シグナルに影響する2012
- Author(s)
  竹島淳史、井上英樹、香座知典、道上康平、渡辺大悟、堀利行
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] C. elegans TRIM/RBCC protein, NHL-1, is involved in heat stress resistance2011
- Author(s)
  井上英樹、香座知典、竹中元彦、堀利行
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] 線虫と哺乳類におけるRASSF とRab-1 の相互作用2011
- Author(s)
  竹島淳史、村田大樹、竹中元彦、香座知典、井上英樹、堀利行
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] Small GTPase Rab39 を介するRASSF の機能解析2011
- Author(s)
  竹中元彦、井上英樹、香座知典、堀利行
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] C. elegans においてRASSF 相同体T24F1.3 はRab GTPase と機能的に相互作用する2011
- Author(s)
  竹中元彦、井上英樹、香座知典、堀利行
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] Autologous stem cell transplantation for 32 patients with multiple myeloma.2010
- Author(s)
  Wataru Kishimoto, Tadakazu Kondo, Kouhei Yamashita, Hiroshi Kawabata, Tatsuo Ichinohe, Akifumi Takaori, Norimitsu Kadowaki, Toshiyuki Hori, Takayuki Ishikawa, Takashi Uchiyama
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] WartsのC.elegans相同体Wts-1と相互作用する細胞分子の探索2010
- Author(s)
  香座知典、井上英樹、竹中元彦、堀利行
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] C.elegansにおけるRASSF相同体T24F1.3の機能解析2010
- Author(s)
  竹中元彦、井上英樹、香座知典、堀利行
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] Poor tolerability to imatinib in elderly CML patients may lead to inadequate responses.2010
- Author(s)
  Masatoshi Nishikawa, Tadakazu Kondo, Masakatsu Hishizawa, Momoko Nishikori, Kohei Yamashita, Toshiyuki Kitano, Tatsuo Ichinohe, Hiroshi Kawabata, Akifumi Takaori, Norimitsu Kadowaki, Toshiyuki Hori, Hiroshi Takayama, Takayuki Ishikawa, Takashi Uchiyama
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] 難治性白血病におけるHippo経路の破綻と治療抵抗性の分子機構2008
- Author(s)
  堀利行、河原真大、蝶名林和久、内山卓
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会館(京都府)(一般口演)
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] Kpm/Lats2 of the Hippo pathway is linked to chemo-sensitivity of leukemic cells.2008
- Author(s)
  Masahiro Kawahara, Toshiyuki Hori, Kazuhisa Chonabayashi, Tsutomu Oka, Marius Sudol, Takashi Uchiyama
- Organizer
  The 50th Annual Meeting of American Society of Hematology
- Place of Presentation
  San Francisco (Poster session)
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] 臍帯血移植後にdonor cell leukemiaを発症した悪性リンパ腫の1例2008
- Author(s)
  山本和代、近藤忠一、菱澤方勝、錦織桃子、山下浩平、一戸辰夫、川端浩、高折晃史、門脇則光、堀利行、石川隆之、内山卓
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会館(京都府)(一般口演)
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] Relationship between the Hippo pathway and DNA damage signals : Kpm/Lats2 affects chemo-sensitivity of leukemic cells2008
- Author(s)
  M. Kawahara, T. Hori, et al.
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] 非血縁者間同種骨髄移植後の非感染性肺合併症:緩和な前処置と従来型前処置の比較2008
- Author(s)
  篠原正信、諌田淳也、一戸辰夫、丸山亙、山本和代、石上隆宏、内山達樹、阪本貴士、藤田晴之、小林正行、錦織桃子、菱澤方勝、川端浩、門脇則光、高折晃史、堀利行、山下浩平、近藤忠一、石川隆之、内山卓
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会館(京都府)(一般口演)
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] 穏和な前処置を用いた同種造血幹細胞移植後の造血器腫瘍再発例の予後に関する検討2008
- Author(s)
  内山達樹、一戸辰夫、丸山亙、山本和代、石上隆宏、篠原正信、阪本貴士、藤田晴之、小林正行、錦織桃子、菱澤方勝、川端浩、門脇則光、高折晃史、堀利行、山下浩平、近藤忠一、石川隆之、内山卓
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会館(京都府)(一般口演)
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] 難治性白血病におけるHippo経路の破綻と治療抵抗性の分子機構2008
- Author(s)
  堀利行, 河原真大, 他2名
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] Relationship between the Hippo pathway and DNA damage signals : Kpm/Lats2 affects chemo-sensitivity of leukemic cells.2008
- Author(s)
  Masahiro Kawahara, Kazuhisa Chonabayashi, Takashi Uchiyama, Tsutomu Oka, Marius Sudol, Toshiyuki Hori
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知)
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] Kpm/Lats2 of the Hippo Pathway Is Linked to Chemo-Sensltivity of Leukemic Cells2008
- Author(s)
  M. Kawahara, T. Hori, et al.
- Organizer
  50^<th> Annual Meeting of American Society of Hematology
- Place of Presentation
  サンフランシスコ(アメリカ合衆国)
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] 単一施設における複数回同種移植に関する検討2008
- Author(s)
  丸山亙、一戸辰夫、山本和代、石上隆宏、内山達樹、篠原正信、阪本貴士、藤田晴之、菱澤方勝、錦織桃子、山下浩平、近藤忠一、川端浩、高折晃史、門脇則光、堀利行、石川隆之、内山卓
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都国際会館(京都府)(一般口演)
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20591122
[Presentation] TRIM/RBCC E3 リガーゼ、NHL-1/TRIM3 はDAF-16/FOXO タンパク質の安定化を介してinsulin/IGF シグナルを制御する
- Author(s)
  井上英樹, 香座知典, 竹島淳史, 堀利行
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、福岡県
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM/RBCC E3リガーゼ、NHL-1/TRIM3はDAF-16/FOXOタンパク質の安定化を介してインスリンシグナルを制御する
- Author(s)
  井上英樹、香座知典、竹島淳史、堀　利行
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] LATS2とE3 SUMO プロテインリガーゼPIAS2の相互作用
- Author(s)
  安田有、渡辺大悟、安藤有美、大賀美咲、香座知典、井上英樹、堀　利行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル、兵庫県
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM/RBCC protein, TRIM3, regulates localization of Yes-associated protein 1 (YAP1)
- Author(s)
  Hideki Inoue, Tomonori Kakura, Motohiko Takenaka, Atsushi Takeshima and Toshiyuki Hori
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、北海道
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] C. elegans のRif1相同体F11E6.7(rif-1) の同定と特性化
- Author(s)
  鎌田顕志，井上英樹，今田亮介，竹中元彦，堀　利行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル、兵庫県
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM3, a TRIM/RBCC protein, interacts with LATS2 and regulates the downstream signals of the Hippo pathway
- Author(s)
  Hideki Inoue, Tomonori Kakura, Atsushi Takeshima, Kouhei Michiue, Daigo Watanabe and Toshiyuki Hori
- Organizer
  Keystone Symposia "The Hippo Tumor Suppressor Network"
- Place of Presentation
  モンテレー、米国
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM/RBCC タンパク質TRIM3 はYAP の局在転移を介してHippo 経路シグナルに影響する
- Author(s)
  竹島淳史, 井上英樹, 香座知典, 道上康平, 渡辺大悟, 堀利行
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、福岡県
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] Tet-On 発現誘導システムを用いたTRIM3の機能解析
- Author(s)
  道上康平、竹島淳史、渡辺大悟、井上英樹、堀　利行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル、兵庫県
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] TRIM3によるLATS2タンパク質安定化の分子機構
- Author(s)
  渡辺大悟、道上康平、竹島淳史、大島遙香、前田木実、井上英樹、堀　利行
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル、兵庫県
- Data Source
  KAKENHI-PROJECT-23501272
[Presentation] 線虫と哺乳類におけるRassfとRif1の相互作用
- Author(s)
  鎌田顕志、井上英樹、今田遼介、竹中元彦、堀　利行
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-23501272

1. UCHIYAMA Takashi (80151900)

# of Collaborated Projects: 9 results

# of Collaborated Products: 12 results
2. YODAI Junji (80108993)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KADOWAKI Norimitsu (60324620)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. INOUE Hideki (20550156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
5. ISHIKAWA Takayuki (10303835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. ICHINOHE Tatsuo (80314219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. HISHIZAWA Masakatsu (90444455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. KAWAMATA Shin (00360842)

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# of Collaborated Products: 0 results
9. HATTORI Toshio (30172935)

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10. MAEDA Michiyuki (20027329)

# of Collaborated Projects: 1 results

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11. MATSUSHITA Shuzo (00199788)

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12. KOYANAGI Yoshio (80215417)

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13. MITUYA Yoshiaki (20136724)

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14. 稲本俊 (10135577)

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15. 熊谷俊一 (00153346)

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16. 寺田雅昭 (10124421)

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17. 新井賢一 (00012782)

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18. 高月清 (80026830)

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19. 高折晃史 (20324626)

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20. 永井美之 (20022874)

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21. ARNE Hormgren

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22. KUBOTA Mamoru

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23. ギーゼラストルツ

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24. スタンコルスマイヤー

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25. パトリック A バウエル

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26. トーマストウルツ

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27. PATUICK A. Baenerle

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28. THOMAS Tursg

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29. STANLEY Korsmyer

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30. GISELA Storg

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31. トムカレン

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32. エミールウナヌエ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. リチャードクラウスナー

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 翠川修

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HORI Toshiyuki 堀 利行

HORI TOSHIYUKI 堀 利行

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Search for RASSF-interacting molecules using C. elegansPrincipal Investigator

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Molecular pathogenesis of abnormal kpm (Lats2) expression in leukemiaPrincipal Investigator

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Involvement of guanylyl cyclase signals of dendritic cells in allergic statePrincipal Investigator

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Characterization of OX40+ T cells detected in patients with GVHD after hematopoietic stem cell transplantationPrincipal Investigator

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ATL細胞に発現するT細胞活性化抗原OX40の病態生理学的意義Principal Investigator

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Immunohematologic studies on the SDF-1/CXCR-4 system with monoclonal antibod.Principal Investigator

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T細胞の癌化に伴って発現誘導される細胞膜蛋白の構造と機能Principal Investigator

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HORI Toshiyuki 堀利行

HORI TOSHIYUKI 堀利行