WAKITANI Shigeyuki 脇谷滋之

… Alternative Names

脇谷滋之ワキタニシゲユキ

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Researcher Number	70243243
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2018: 武庫川女子大学, 健康・スポーツ科学部, 教授 2016: 武庫川女子大学, 健康スポーツ科学部, 教授 2012 – 2015: 武庫川女子大学, スポーツ健康科学部, 教授 2011 – 2013: 武庫川女子大学, 健康・スポーツ科学部, 教授 2007 – 2010: Osaka City University, Graduate School of Medicine Orthopaedic Surgery, Associate professor … More 2007 – 2008: Osaka City University, School ofmedicine, Associate Professor 2006: 大阪市立大学, 大学院・医学研究科, 講師 2006: 大阪市立大学, 大学院医学研究科, 講師 2005 – 2006: 大阪市立大学, 医学部, 講師 2004 – 2005: Shinshu University, University Hospital, lecturer, 医学部附属病院, 講師 2002 – 2004: 信州大学, 医学部, 講師 2002 – 2003: 信州大学, 医学部・整形外科, 講師 1993: 大阪大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Orthopaedic surgery / Morphological basic dentistry / Rehabilitation science/Welfare engineering / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science
Keywords	Principal Investigator KLF9 / 軟骨分化 / articular cartilage repair / chondrocyte differentiation factor / undifferentiated mesenchymal cells / 骨形成因子 / 超音波遺伝子導入 / 遺伝子発現 / 遺伝子解析 / 転写因子 … More / 軟骨分化促進 / 関節軟骨修復 / 軟骨分化促進因子 / 未分化間葉系細胞 / 骨髄 / 関節鏡視下手術 / 軟骨シート / 体性幹細胞 / 軟骨修復 / 浸透圧 / シート培養 / 間葉系幹細胞 / 骨軟骨欠損 / 軟骨細胞シート / 骨髄間葉系幹細胞 / 関節軟骨再生 / 骨・軟骨代謝学 / 血液由来細胞 / 自然修復 / 軟骨欠損 / 血流共有モデル / Stem Cell Mobilization / 修復細胞 / G-CSF / 末梢血中有核細胞 / 骨軟骨欠損修復 / 骨軟骨再生 / 細胞・組織 / 再生医療 … More Except Principal Investigator 再生医療 / sonoporation / drug delivery system / 修復 / 半月板 / anti cancer drug / electrochemotherapy / 生体吸収性ポリマー / cartilage / 間葉系細胞 / 軟骨 / 半月板修復 / 半月修復 / BMP / 転写調節因子 / MAPK / p38シグナル / Wntシグナル / 軟骨細胞 / Irx3 / SDF-1/CXCR4システム / 半月板治癒促進 / SDF1 / SDF-1 / 再生 / 老化関連因子 / オートファジー / Nｒｆ２ / 加齢性筋委縮 / miRNA / miR-155 / miRNA-155 / Nrf2 / 筋衛星細胞 / サルコペニア / sports / cell transplantation / mesenchymal stromal cell / children / elbow joint / regenerative medicine / articular cartilage / MRI診断 / 骨髄間葉細胞 / 軟骨再生 / スポーツ / 細胞移植 / 骨髄間葉系細胞 / 小児 / 肘関節 / 関節軟骨 / nano-particle / ドラッグデリバリー / 電気刺激 / 抗癌剤 / ドラックデリバリー / 超音波刺激 / ナノパーティクル / biomaterial / CAD / polymer / regeneration / bone / ポリマー材料 / 薬物伝達系 / 骨欠損修復 / 人工関節 / 骨形成タンパク / 骨形成 / コンピューター支援デザイン / 骨欠損 / 骨修復 / 生体材料 / 骨形成蛋白 / 骨再生 / methotrexate / arthritis / electrolode / drug delivety system / メトトレキサート / 関節炎 / 電極 / 抗腫瘍剤 / 電気化学療法 / biodegradable polymer / physical loading / culture apparatus / pressurization / aggrecan / collagen gel / three-dimensional culture / 力学的刺激 / 培養装置 / 圧力負荷 / アグリカン / コラーゲンゲル / 三次元培養 / mesenchymal cell / collagen / gene / repair / 転写因子 / コラーゲン / 遺伝子 / Sensitization / Carbohydrate / Oncofetal membrane marker / Rheumatoid arthritis / 感作療法 / 糖鎖抗原 / 癌 / 慢性関節リウマチ / サイトカイン / PRF / 入力お願いいたします / フィブリンゲル / 単核球 / フィブリン / 半月板再生 / マクロファージ / 血流由来細胞 / パラバイオシス / PTH / CREB / シグナル伝達 / 骨芽細胞様細胞 / cAMP / サイクリックAMP / 細胞内情報伝達系 / 骨形成因子 / 副甲状腺ホルモン / 非侵襲的 / 細胞形態 / 間葉系幹細胞 / 診断 / 細胞分化 Less

Homeostatic changes in muscle satellite cells and involvement of Nrf2 / autophagy system in age-related myopathy
- Principal Investigator
  
  Itokazu Maki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kindai University
Mechanism of meniscal healing and clinical application through SDF-1/CXCR4 signaling pathway
- Principal Investigator
  
  Minoda Yukihide
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka City University
Character of platelet rich fibrin and effect for meniscal healing
- Principal Investigator
  
  Hashimoto Yusuke
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka City University
Role of Irx3 in chondrogenic differentiation and chondrocyte maturation of mouse mesenchymal cells
- Principal Investigator
  
  Tamamura Yoshihiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Mukogawa Women's University
InvestigationPrincipal Investigator
- Principal Investigator
  
  WAKITANI Shigeyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Mukogawa Women's University
Circulating nucleated peripheral blood cells contribute to early-phase meniscal healing
- Principal Investigator
  
  MINODA Yukihide
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka City University
Research the origin of cells that contribute to the repair of osteochondral defect and application this for the acceleration of the tissue repair.Principal Investigator
- Principal Investigator
  
  WAKITANI Shigeyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Mukogawa Women's University
  Osaka City University
Development of noninvasive estimation of differentiation from stemcells
- Principal Investigator
  
  TAKAGI Mutsumi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
Crosstalk of intra-cellular signaling pathway in bone formation
- Principal Investigator
  
  KOIKE Tatsuya
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka City University
Autologous culture expanded bone marrow stromal cell transplantation for capitellar osteochondritis dissecans
- Principal Investigator
  
  KATO Hiroyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Nano-particles which Contained Drug Induction into Tumor Cell by Electrochemotherapy and Sonoporation
- Principal Investigator
  
  TAKAHASHI Jun, 清水富永
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Development of comprehensive technology for practical use of bone-inducing capacity of synthesized BMP
- Principal Investigator
  
  TAKAOKA Kunio
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka City University
Comprehensive gene expression analysis during chondrogenesis from progenitor cells, ,and application of this technique to tissue repairPrincipal Investigator
- Principal Investigator
  
  WAKITANI Shigeyuki
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka City University
  Shinshu University
Organization of Electrolodes for the Electrochemotherapy for Deep-seated Malignant Musculoskeletal Tumor
- Principal Investigator
  
  SHIMIZU Tominaga
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Shinshu University
Genes associated with cartilage differentiation and their application to cartilage repair
- Principal Investigator
  
  KIMURA Tomoatsu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Regeneration of cartilage from autologous stem cells employing a loading system of physiological stress
- Principal Investigator
  
  TAKAGI Mutsumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
  Osaka University
癌細胞特異糖鎖抗原による慢性関節リウマチ患者に対する感作療法
- Principal Investigator
  
  OCHI Takahiro
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University

All 2017 2016 2015 2014 2013 2012 2011 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] Autologus culture expanded bone marrow stromal cell transplantation for cartilage repair. Bone marrow transplantation: new research.2006
- Author(s)
  Wakitani S, Kato H., et. al.
- Publisher
  Nova Sciences Publishers, Inc.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591659
[Book] Autologus culture expanded bone marrow stromal cell transplantation for cartilage repair.2006
- Author(s)
  Wakitani S, Ohgushi H, Kato H, et al.
- Total Pages
  12
- Publisher
  2006 Nova Science Publishes, Inc.
- Data Source
  KAKENHI-PROJECT-18591659
[Book] Bone marrow transplantation2006
- Author(s)
  Wakitani S, Ohgushi H, Machida H, Nakaya H, Murakami N, Yamasaki H, Kato H, Kawaguchi A, Okabe T, Tensho K
- Publisher
  Autologous culture expanded bone marrow stromal cell transplantation for cartilage repair.
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Irx3 and Bmp2 regulate mouse mesenchymal cell chondrogenic differentiation in both a Sox9-dependent and -independent manner2017
- Author(s)
  Tamamura Y, Katsube K, Mera H, Itokazu M, Wakitani S
- Journal Title
  
  J. Cell. Physiol.
  
  Volume: 印刷中 Issue: 12 Pages: 3317-3336
- DOI
  10.1002/jcp.25776
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462805, KAKENHI-PROJECT-17K01044, KAKENHI-PROJECT-17K11636
[Journal Article] Transplantation of Scaffold-free Cartilage-Like Cell Sheets Made from Human Bone Marrow Mesenchymal Stem Cells for Cartilage Repair: Preclinical Study2016
- Author(s)
  Maki Itokazu, Shigeyuki Wakitani, Hisashi Mera, Yoshihiro Tamamura, Yasushi Sato, Mutsumi Takagi, Hiroaki Nakamura
- Journal Title
  
  Cartilage
  
  Volume: 9 Issue: 4 Pages: 1-12
- DOI
  10.1177/1947603515627342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462805, KAKENHI-PROJECT-14J00491
[Journal Article] 骨髄間葉系幹細胞からの軟骨様細胞シートの作成および移植（前臨床試験）2015
- Author(s)
  糸数万紀、目良恒、玉村禎宏、高木睦、脇谷滋之
- Journal Title
  
  関節外科
  
  Volume: 34 Pages: 108-117
- Data Source
  KAKENHI-PROJECT-26462805
[Journal Article] 骨髄間葉系幹細胞からの軟骨様細胞シートの作製及び移植（前臨床試験）2015
- Author(s)
  糸数万紀、目良恒、玉村禎宏、高木睦、脇谷滋之
- Journal Title
  
  関節外科
  
  Volume: 34
- Data Source
  KAKENHI-PROJECT-24390361
[Journal Article] Circulating nucleated peripheral blood cells contribute to early-phase meniscal healing2014
- Author(s)
  Shinya Yamasaki, Yusuke Hashimoto, Junsei Takigami, Shozaburo Terai, Masafumi Takahashi,Shigeyuki Wakitani and Hiroaki Nakamura
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462275
[Journal Article] Cartilage repair with autologous bone marrow mesenchymal stem cell transplantation: review of pre-clinical and clinical studies.2014
- Author(s)
  Yamasaki S, Mera H, Itokazu M, Hashimoto Y, Wakitani S.
- Journal Title
  
  Cartilage e-pub on May 19, 2014
  
  Volume: e-pub on May 19 Issue: 1 Pages: 2014-2014
- DOI
  10.1177/1947603514551553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390361
[Journal Article] Xeno-free and shrinkage-free preparation of scaffold-free cartilage-like disc-shaped cell sheet using human bone marrow mesenchymal stem cells.2013
- Author(s)
  Yasushi Sato, Sigeyuki Wakitani, Mutsumi Takagi
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 116 Pages: 734-739
- NAID
  110009687838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390361
[Journal Article] 骨髄間葉系細胞移植による軟骨再生治療2013
- Author(s)
  目良恒、脇谷滋之
- Journal Title
  
  Pharma Medica
  
  Volume: 31 Pages: 21-24
- Data Source
  KAKENHI-PROJECT-24390361
[Journal Article] Nucleated cells circulating in the peripheral blood contribute to the repair of osteochondral defects only in the early phase of healing2012
- Author(s)
  Okano T, Wakitani S, Okabe T, Takahashi M, Koike T, Nakamura H
- Journal Title
  
  J Tissue Eng Regen Med in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591953
[Journal Article] RNA interference for Noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro2009
- Author(s)
  Takayama K, Suzuki A, Manaka T, Taguchi S, Hashimoto Y, Imai Y, Wakitani S, Takaoka K
- Journal Title
  
  J Bone Miner Metab, Online Feb 28
- NAID
  10027204830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390421
[Journal Article] Correlation between cell morphology andaggrecan gene expression level duringdifferentiation from mesenchymal stemcells to chondrocytes2008
- Author(s)
  M. Takagi, T. Kitabayashi, S. Koizumi,H. Hirose, S. Kondo, M. Fujiwara, K. Ueno,H. Misawa, Y. Hosokawa, H. Masuhara and S. Wakitani
- Journal Title
  
  Biotechnology Letters 30
  
  Pages: 1189-1195
- Data Source
  KAKENHI-PROJECT-18300144
[Journal Article] Serum keratan sulfate is a promising marker of early articular cartilage breakdown2007
- Author(s)
  Wakitani S, et. al.
- Journal Title
  
  Rheumatology(Oxford) 46
  
  Pages: 1652-1656
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Detection of gene expression in synovium of patients with osteoarthritis using a random sequencing method2007
- Author(s)
  Okabe T, Ohmori Y, Tanigami A, Hishigaki H, Suzuki Y, Sugano S, Kawaguchi A, Nakaya H, Wakitani S
- Journal Title
  
  Acta Orthop 78
  
  Pages: 687-692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390421
[Journal Article] Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation:three case reports involving 9 defects in 5 knees.2007
- Author(s)
  Wakitani S, et. al.
- Journal Title
  
  J Tissue Engineering Regenerative Medicine 1
  
  Pages: 74-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] High inoculation cell density could accelerate the differentiation of human bone marrow mesenchymal stem cells to chondr ocyte cells.2007
- Author(s)
  Takagi M, Wakitani S, et. al.
- Journal Title
  
  J Biosci Bioeng 103
  
  Pages: 98-100
- NAID
  110006164023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation : three case reports involving 9 defects in 5 knees2007
- Author(s)
  Wakitani, S., et. al.
- Journal Title
  
  J Tissue Engineering Regenerative Medicine 1
  
  Pages: 74-49
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591659
[Journal Article] Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation: three case reports involving 9 defects in 5 knees.2007
- Author(s)
  Wakitani S, et. al.
- Journal Title
  
  J Tissue Engineering Regenerative Medicine 1
  
  Pages: 74-79
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591659
[Journal Article] Detection of gene expression in synovium of patients with osteoarthritis using a random sequencing method.2007
- Author(s)
  Okabe T, Wakitani S, et. al.
- Journal Title
  
  Acta Orthop 78
  
  Pages: 687-692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation : three case reports involving 9 defects in 5 knees.2007
- Author(s)
  Wakitani S, Nawata M, Tensho K., et al.
- Journal Title
  
  J Tissue Engineering Regenerative Medicine (in press)
  
  Pages: 2007-2007
- Data Source
  KAKENHI-PROJECT-18591659
[Journal Article] High inoculation cell density could accelerate the different iation of human bone marrow mesenchymal stem cells to chondrocyte cells2007
- Author(s)
  Takagi M, Wakitani S, et. al.
- Journal Title
  
  J Biosci Bioeng 103
  
  Pages: 98-100
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] BMPによる骨再生-人工股関節周囲巨大骨欠損への応用2007
- Author(s)
  星野雅俊、脇谷滋之、大田陽一、岩切健太郎、高岡邦夫
- Journal Title
  
  人工臓器 36
  
  Pages: 195-197
- NAID
  10025704014
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] Serum keratan sulfate is a promising marker of early articular cartilage breakdown2007
- Author(s)
  Wakitani, S., et. al.
- Journal Title
  
  Rheumatology (Oxford) 46
  
  Pages: 1652-1656
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Detection of gene expression in synovirm of patients with osteoarthritis using a random sequencing method2007
- Author(s)
  Okabe T, Wakitani S, et. al.
- Journal Title
  
  Acta Orthop 78
  
  Pages: 687-692
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation:three case reports involving 9 defects in 5 knees2007
- Author(s)
  Wakitani S, et. al.
- Journal Title
  
  J Tissue Engineering Regenerative Medicine 1
  
  Pages: 74-79
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation: three case reports involving 9 defects in 5 knees2007
- Author(s)
  Wakitani, S., et. al.
- Journal Title
  
  J Tissue Engineering Regenerative Medicine 1
  
  Pages: 74-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Serum keratan sulfate is a promising marker of early articular cartilage breakdown.2007
- Author(s)
  Wakitani S, et. al.
- Journal Title
  
  Rheumatology(Oxford) 46
  
  Pages: 1652-1656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Immunohistochemical localization of alpha-Smooth muscle actin during rat molar tooth development.2006
- Author(s)
  Hosoya A, Wakitani S. et al.
- Journal Title
  
  J Histochem Cytochem. 54(12)
  
  Pages: 1371-1378
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591559
[Journal Article] Co-ordinate expression of BMP-2, BMP receptors and Noggin in normal mouse spine.2006
- Author(s)
  Nakamura Y, Nakaya H, Saito N, Wakitani S
- Journal Title
  
  J Clinical Neuroscience 13
  
  Pages: 250-256
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Co-ordinate expression of BMP-2, BMP receptors and Noggin in normal mouse spine2006
- Author(s)
  Nakamura Y, Nakaya H, Saito N, Wakitani S
- Journal Title
  
  J Clinical Neuroscience 13
  
  Pages: 250-256
- Data Source
  KAKENHI-PROJECT-18390421
[Journal Article] Autologus culture expanded bone marrow stromal cell transplantation for cartilage repair2006
- Author(s)
  Wakitani, S., Kato, H., et. al.
- Journal Title
  
  Nova Sciences Publishers, Inc. Bone marrow transplantation new research
  
  Pages: 97-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591659
[Journal Article] Microbubble-enhanced ultrasound exposure promotes uptake of methotrexate into synovial cells and enhanced anti-inflammatory effects in the knees of rabbits with antigen-induced arthritis.2005
- Author(s)
  Nakaya, H., Shimizu, T., sobe, IK., Tenshou, K., Okabe, T., Nakamura, Y., Nawata, M., Yoshikawa, H., Takaoka, K., Wakitani, S
- Journal Title
  
  Arthritis & Rheumatism 52
  
  Pages: 2559-2566
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] Use of bone morphogenetic protein 2 and diffusion chambers to engineer cartilage tissue for the repair of defects in articular cartilage2005
- Author(s)
  Nawata, M., Wakitani, S., Nakayta, A., Tanigami, A., Seki, T., Nakamura, Y., Saito, N., Sano, K., Hidaka, E., Takaoka, K
- Journal Title
  
  Arthritis & Rheumatism 52
  
  Pages: 155-163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] Use of bone morphogenetic protein 2 and diffusion chambers to engineer cartilage tissue for the repair of defects in articular cartilage2005
- Author(s)
  Nawata M, Wakitani S, Nakayta A, Tanigami A, Seki T, Nakamura Y, Saito N, Sano K, Hidaka E, Takaoka K.
- Journal Title
  
  Arthritis & Rheumatism 52
  
  Pages: 155-163
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] Expression profiles of BMP-related molecules induced by BMP or BMP-4 inmuscle-derived primary culture cells2005
- Author(s)
  Nakamura Y, Wakitani S, Saito N, Takaoka K.
- Journal Title
  
  J, Bone & Miner.Metab 23
  
  Pages: 426-434
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] The effect of heat on biological activity of recombinant BMP-22005
- Author(s)
  Ohta H, Wakitani S, Tenshou K, Horiuchi H, Wakabayashi S, Saito N, Nakamura Y, Nozaki K, Imai Y, Takaoka K.
- Journal Title
  
  J, Bone & Miner.Metab 23
  
  Pages: 420-425
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] The effect of heat on biological activity of recombinant BMP-2.2005
- Author(s)
  Ohta, H., Wakitani, S., Tenshou, K., Horiuchi, H., Wakabayashi, S., Saito, N., Nakamura, Y., Nozaki, K., Imai, Y., Takaoka, K
- Journal Title
  
  J, Bone & Miner. Metab 23
  
  Pages: 420-425
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] Microbubble-enhanced ultrasound exposure promotes uptake of methotrexate into synovial cells and enhanced anti-inflammatory effects in the knees of rabbits with antigen-induced arthritis2005
- Author(s)
  Nakaya, H.Shimizu, T., Isobe K., Tenshou, K., Okabe, T.Nakamura, Y., Nawata, M., Yoshikawa, H.Takaoka, K.and Wakitani, S.
- Journal Title
  
  Arthritis & Rheumatism 52
  
  Pages: 2559-2566
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] Expression profiles of BMP-related molecules induced by BMP or BMP-4 in muscle-derived primary culture cells.2005
- Author(s)
  Nakamura, Y., Wakitani, S., Saito, N., Takaoka, K
- Journal Title
  
  J, Bone & Miner. Metab 23
  
  Pages: 426-434
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16109009
[Journal Article] Nucleated cells circulating in the peripheral blood contribute to the repair of osteochondral defects only in the early phase of healing
- Author(s)
  Okano T, Wakitani S, Okabe T, Takahashi M, Koike T, Nakamura H
- Journal Title
  
  J Tissue Eng Regen Med
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21591953
[Journal Article] Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation : three case reports involving 9 defects in 5 knees.
- Author(s)
  Wakitani S, Nawata M, Tensho K, Okabe Y, Machida H, Ohgushi H
- Journal Title
  
  J Tissue Engineering Regenerative Medicine In press
- Data Source
  KAKENHI-PROJECT-16390436
[Journal Article] Gene expression in synovium of patients with osteoarthritis using random sequencing method.
- Author(s)
  Okabe T, Ohmori Y, Tanigami A, Hishigaki H, Suzuki Y, Sugano S, Kawaguchi A, Nakaya H, Wakitani S
- Journal Title
  
  Acta Orthop In press
- Data Source
  KAKENHI-PROJECT-16390436
[Presentation] ヒト骨髄細胞由来scafford-free再生軟骨様細胞シート作成の工夫2014
- Author(s)
  糸数万紀、目良恒、佐藤康史、中村博亮、高木睦、脇谷滋之
- Organizer
  第27回日本軟骨代謝学会
- Place of Presentation
  京都府医師会館
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] The enhancement of human bone marrow derived mesenchymal stem cells (hBMSCs) for scaffold-free cartilage-like cell-sheets2014
- Author(s)
  Itokazu M, Mera H, Sato Y, Nakamura H, Takagi M, Wakitani S.
- Organizer
  60TH ANNNUAL MEETING of Osteoarthritis Research Society International 2014 world congress,
- Place of Presentation
  Paris（France)
- Year and Date
  2014-04-23
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] 骨髄間葉系幹細胞を用いた軟骨様細胞シートのECM蓄積量増大法の検討2013
- Author(s)
  佐藤康史、笠井信宏、高橋伊織、脇谷滋之、高木睦
- Organizer
  日本生物工学会年会広島大会
- Place of Presentation
  広島国際会議場
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] Cartilage repair with autologous bone marrow mesenchymal stem cells in OA joints2013
- Author(s)
  Wakitani S
- Organizer
  11th World Congress of International Cartilage Repair Society
- Place of Presentation
  Izmir
- Invited
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] Clinical experience of stem cell implantation in an OA joint2013
- Author(s)
  Wakitani S
- Organizer
  1st Summit meeting of International Cartilage Repair Society
- Place of Presentation
  Tallin
- Invited
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] 隔膜培養器と骨髄間葉系幹細胞を用いたスキャフォールドフリー軟骨様細胞シート作製2012
- Author(s)
  佐藤康史、脇谷滋之、高木睦
- Organizer
  日本再生医療学会
- Place of Presentation
  横浜
- Year and Date
  2012-06-13
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] Xeno-free Preparation of Scaffold-free Cartilage-like Cell Sheet using Bone Marrow Mesenchymal Stem Cells2012
- Author(s)
  Sato S, Wakitani S, Takagi M
- Organizer
  日本動物細胞工学会国際大会
- Place of Presentation
  名古屋
- Year and Date
  2012-11-30
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] 隔膜培養器と骨髄間葉系幹細胞を用いたスキャフォールドフリー軟骨様細胞シート作製2012
- Author(s)
  佐藤康史、脇谷滋之、高木睦
- Organizer
  日本生物工学会
- Place of Presentation
  神戸
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] 骨髄間葉系細胞を用いた関節軟骨再生2012
- Author(s)
  脇谷滋之
- Organizer
  日本整形外科学会
- Place of Presentation
  京都
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] Stem cell mobilizationによる骨軟骨欠損修復2011
- Author(s)
  岡野匡志、脇谷滋之、安田宏之、渭川徹秀、山田賢太郎、岡部高弘、川口杏夢、中村博亮
- Organizer
  第26回日本整形外科学会基礎学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-21591953
[Presentation] NONINVASIVE ESTIMATION OF AGGRECAN GENE EXPRESSION LEVEL BASED ON CELL MORPHOLOGY ANALYSISDURING DIFFERENTIATION FROM HUMANMESENCHYMAL STEM CELLS TO CHONDROCYTES2008
- Author(s)
  高木睦、北林孝之、小泉覚、廣瀬遥香、藤原政司、上野貢生、三澤弘明、細川陽一郎、増原宏、脇谷滋之香、藤原政司、上野貢生
- Organizer
  JAACT2008
- Place of Presentation
  福岡、福岡国際会議場
- Year and Date
  2008-11-24
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] 間葉系幹細胞から軟骨細胞への分化度の細胞形態による非侵襲的モニタリング法開発2008
- Author(s)
  高木睦、北林孝之、小泉覚、廣瀬遥香、藤原政司、上野貢生、三澤弘明、細川陽一郎、増原宏、脇谷滋之
- Organizer
  再生医療学会
- Place of Presentation
  名古屋、名古屋国際会議場
- Year and Date
  2008-03-13
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] Noninvasive Estimation of the Aggrecan Gene ExpressionRate during Differentiation from Mesenchymal Stem Cells to ChondrocytesBased on Morphological Analysis2007
- Author(s)
  高木睦、北林孝之、小泉覚、近藤真一、藤原政司、上野貢生、三澤弘明、細川陽一郎、増原宏、脇谷滋之
- Organizer
  国際再生医療学会(TERMIS-AP 2007)
- Place of Presentation
  東京、グランドプリンスホテル赤坂
- Year and Date
  2007-12-03
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] Cartilage repair with bone marrow mesenchymal cells -its preparation and clinical use-2007
- Author(s)
  Wakitani, S
- Organizer
  2007 Bioengineering for Cell Therapy. Ajou Cell Therapy Center
- Place of Presentation
  Suwan, Korea
- Year and Date
  2007-03-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390436
[Presentation] 間葉系幹細胞から軟骨細胞への分化の細胞形態による非侵襲的診断法開発2007
- Author(s)
  高木睦、北林孝之、小泉覚、藤原政司、上野貢生、三澤弘明、細川陽一郎、増原宏、脇谷滋之
- Organizer
  日本生物工学会年会
- Place of Presentation
  東広島、広島大学
- Year and Date
  2007-09-25
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] Cartilage repair with bone marrow mesenchymal cells-its preparation and clinical use2007
- Author(s)
  Wakitani S.
- Organizer
  2007 Bioengineering for Cell Therapy. Ajou Cell Therapy Center
- Place of Presentation
  Ajjou University,in Suwan,Korea
- Year and Date
  2007-03-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390436
[Presentation] 間葉系幹細胞から軟骨細胞への分化の細胞形態による非侵襲的診断法開発2007
- Author(s)
  高木睦、北林孝之、小泉覚、藤原政司、上野貢生、三澤弘明、細川陽一郎、増原宏、脇谷滋之
- Organizer
  化学工学会秋季大会
- Place of Presentation
  札幌、北海道大学
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] フェムト秒レーザーを利用した単一接着細胞の遺伝子発現解析2006
- Author(s)
  高木睦、北林孝之、藤原政司、上野貢生、三澤弘明、細川陽一郎、増原宏、脇谷滋之
- Organizer
  日本生物工学会
- Place of Presentation
  豊中、大阪大学豊中キャンパス
- Year and Date
  2006-09-11
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] 顕微鏡画像による間葉系幹細胞からの軟骨細胞への分化度診断の試み2006
- Author(s)
  高木睦、近藤真一、小泉覚、梅津洋介、藤原政司、脇谷滋之
- Organizer
  日本再生医療学会年会
- Place of Presentation
  岡山、岡山コンベンションセンター
- Year and Date
  2006-03-08
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] 間葉系幹細胞から軟骨細胞への分化培養における細胞形態解析による分化度の診断2005
- Author(s)
  高木睦、近藤真一、梅津洋介、藤原政司、脇谷滋之
- Organizer
  日本生物工学会年会
- Place of Presentation
  筑波、つくば国際会議場
- Year and Date
  2005-11-15
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] 間葉系幹細胞から軟骨細胞への分化培養における細胞形態によるアグリカン発現率の診断2005
- Author(s)
  高木睦、近藤真一、服部裕美、梅津洋介、藤原政司、脇谷滋之
- Organizer
  再生医療学会
- Place of Presentation
  大阪、大阪国際会議場
- Year and Date
  2005-03-01
- Data Source
  KAKENHI-PROJECT-18300144
[Presentation] ヒト骨髄細胞由来scafford-free再生軟骨様細胞シート作成の工夫
- Author(s)
  糸数万紀、目良恒、佐藤康史、中村博亮、高木睦、脇谷滋之
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル（鹿児島県鹿児島市）
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] ヒト骨髄細胞（hBMSCs）由来scaffold-free再生軟骨細胞シート作成の工夫
- Author(s)
  糸数万紀、目良恒、佐藤康史、中村博亮、高木睦、脇谷滋之
- Organizer
  第６回日本関節鏡・膝・スポーツ整形外科学会
- Place of Presentation
  広島国際会議場（広島県広島市）
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] 転写調節因子Irx3の初期軟骨細胞分化における役割について
- Author(s)
  玉村禎宏、目良恒、糸数万紀、脇谷滋之
- Organizer
  第28回日本軟骨代謝学会
- Place of Presentation
  東京医科歯科大学（東京都、文京区、湯島）
- Year and Date
  2015-03-06 – 2015-03-07
- Data Source
  KAKENHI-PROJECT-26462805
[Presentation] Nucleated cells circulating in the peripheral blood Contribute to Meniscus Healing during mainly Early-Phase
- Author(s)
  Shinya Yamasaki, Yusuke Hashimoto, Junsei Takigami, Shozaburo Terai, Masafumi Takahashi, Shigeyuki Wakitani, Hiroaki Nakamura
- Organizer
  60th Annual meeting of Orthopaedic Research Society
- Place of Presentation
  Hyatt Regency New Olreans,New Olreans,USA
- Data Source
  KAKENHI-PROJECT-24592275
[Presentation] Increase of Type 2 collagen Accumulation in Shrinkage-free Scaffold-free Cartilage-like MSCs Sheet.
- Author(s)
  Sato Y, Wakitani S, Takagi M.
- Organizer
  TERMIS-AM
- Place of Presentation
  Washington DC（USA)
- Year and Date
  2014-12-13 – 2014-12-16
- Data Source
  KAKENHI-PROJECT-24390361
[Presentation] 骨髄間葉系幹細胞からの軟骨様シートの作成および移植
- Author(s)
  糸数万紀、目良恒、中村博亮、高木睦、脇谷滋之
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル（鹿児島県鹿児島市）
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24390361

1. HASHIMOTO Yusuke (10382178)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. TAKAGI Mutsumi (20263212)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
3. MINODA Yukihide (90453133)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SHIMIZU Tominaga (40283270)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAKAHASHI Jun (60345741)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TAMAMURA Sadahiro (70431963)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. KIMURA Tomoatu (80167379)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NIKAIDO Toshio (50180568)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TAKAOKA Kunio (30112048)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
10. KATAGIRI Takenobu (80245802)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. ORITA Kumi (40748597)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KADOYA Masumi (40115225)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. FUJIWARA Masashi (30229075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
14. KOIKE Tatsuya (50271177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HOSHI Manabu (50445037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAMURA Hiroaki (60227931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. IWAKI Hiroyoshi (20381981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. OCHI Takahiro (80112035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OWAKI Hajime (60223872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MORITA Yuji (30313604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MATSUSHITA Isao (80345587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KAZUKI Kennichi (80254407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. FURUTA Masakazu (40181458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. ISOBE Kenichi (80397314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KATO Hiroyuki (40204490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
26. OHGUSHI Hajime (80213669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. TAKAHARA Masatosbi (10236341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. YOSHIMURA Yasuo (10303439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. Itokazu Maki (90780015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. MERA Hisashi (70650381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
31. 小野啓郎 (70028330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 遊道和雄 (60272928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 松野博明 (00219461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 吉田敏臣 (00029290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 小林章郎 (70285287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 大橋弘嗣 (70254406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 村上成道 (50334892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 寺村岳士 (40460901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 福田寛二 (50201744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 谷上信

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

WAKITANI Shigeyuki 脇谷 滋之

脇谷 滋之 ワキタニ シゲユキ

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Research the origin of cells that contribute to the repair of osteochondral defect and application this for the acceleration of the tissue repair.Principal Investigator

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Comprehensive gene expression analysis during chondrogenesis from progenitor cells, ,and application of this technique to tissue repairPrincipal Investigator

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WAKITANI Shigeyuki 脇谷滋之

脇谷滋之ワキタニシゲユキ