HASHIMOTO Fumio 橋本文雄

Researcher Number	70244142
Other IDs
External Links
Affiliation (Current)	2025: 鹿児島大学, 農水産獣医学域農学系, 教授
Affiliation (based on the past Project Information) *help	2015 – 2021: 鹿児島大学, 農水産獣医学域農学系, 教授 2012 – 2014: 鹿児島大学, 農学部, 教授 2011: 鹿児島大学, 農学部, 准教授 2007 – 2008: 鹿児島大学, 農学部, 准教授 2006: 鹿児島大学, 農学部, 助教授 1997 – 1998: 鹿児島大学, 農学部, 助教授 1996: 熊本大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Horticultural science / Horticulture/Landscape architecture / Chemical pharmacy Except Principal Investigator Food science / Basic Section 39030:Horticultural science-related / Horticultural science / 医薬分子機能学
Keywords	Principal Investigator 遺伝育種 / 遺伝生化学 / アントシアニン / 複対立遺伝 / トルコギキョウ / チューリップ / 化学分類 / 園芸利用 / diosgenin / solasodine … More / steroidal alkaloid / HMG CoA reductase / Solanum viarum / 26-aminocholesterol … More Except Principal Investigator アントシアニン / 花色 / トルコギキョウ / 細胞癌化抑制能 / 遺伝子組換え / コピグメンテーション / フラボノール / グルコシル化 / 遺伝学 / 植物 / 遺伝子 / 育種学 / 園芸学 / 花色育種 / 花卉 / 分子育種 / F3H / トランスポゾンディスプレイ / 突然変異 / 斑入り / 突然変異育種 / トランスポゾン / Ursolic acid / Oleanolic acid / Betulinic acid / Triterpenoids / Anti-HIV / ベツリン酸 / ウルソール酸 / オレアノール酸 / ぺツリン酸 / トリテルペノイド / 抗AIDS作用 / 結合解析 / MAP キナーゼ / 炎症抑制能 / 結合モデル構築 / 直接結合能 / 親和力 / MAPキナーゼ / 細胞標的分子 / 食品機能性 / 分子作用機構 / NF-kB / 細胞シグナル伝達 / 食品分子作用機構 / MEK1 / 分子標的 / 分子機構 / 標的分子 / シグナル伝達 / 細胞がん化 Less

Flower color modification through interaction between B-ring glycosylated delphinidins and flavonols in Eustoma grandiflorum
- Principal Investigator
  
  Noda Naonobu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 39030:Horticultural science-related
- Research Institution
  National Agriculture and Food Research Organization
Analysis and utilization of transposon isolated from a variegated flower line in Eustoma grandiflorumm
- Principal Investigator
  
  Shimizu Keiichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Horticultural science
- Research Institution
  Kagoshima University
Breeding method for creating new types of flower colors of EustomaPrincipal Investigator
- Principal Investigator
  
  Hashimoto Fumio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Horticultural science
- Research Institution
  Kagoshima University
Chemosystematic of Tulips based on tepal anthocyanins as phenetic markersPrincipal Investigator
- Principal Investigator
  
  HASHIMOTO Fumio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Horticulture/Landscape architecture
- Research Institution
  Kagoshima University
Clarification of the molecular targets for bioactive anthocyanins: MAP kinase as direct targets
- Principal Investigator
  
  HOU De-Xing
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kagoshima University
Signaling pathways for the inhibition of cell transformation by anthocyanins
- Principal Investigator
  
  HOU De-xing
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kagoshima University
Colaborative Research on Anti-HIV Triterpenoids
- Principal Investigator
  
  KASHIWADA Yoshiki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Niigata College of Pharmacy
新規抗脂血症用薬"26-aminocholesterol"合成法の開発Principal Investigator
- Principal Investigator
  
  橋本文雄
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kumamoto University

All 2017 2016 2015 2014 2013 2012 2011 2007

All Journal Article Presentation Patent

[Journal Article] Efficiency of Hand-thinning in Apple Cultivars with Varying Degrees of Fruit Abscission2015
- Author(s)
  Yuka Takatori, Keiichi Shimizu, Jun Ogata, Hiroki Endo, Kanji Ishimaru, Shigehisa Okamoto, Fumio Hashimoto.
- Journal Title
  
  The Horticulture Journal
  
  Volume: 84 Issue: 2 Pages: 99-105
- DOI
  10.2503/hortj.CH-112
- NAID
  130005066775
- ISSN
  2189-0102, 2189-0110
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450040
[Journal Article] 野生種トルコギキョウを起源とする二重咲き花形の遺伝様式2015
- Author(s)
  髙取由佳, 櫟本裕太郎, 清水圭一, 橋本文雄
- Journal Title
  
  園芸学研究
  
  Volume: 3
- NAID
  130005117153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450040
[Journal Article] Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea2014
- Author(s)
  Zar PPK, Moroshita A, Hashimoto F, Sakao K, Fujii M, Wada K, Hou DX*
- Journal Title
  
  J Functional Foods
  
  Volume: 6 Pages: 523-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580176
[Journal Article] Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea2014
- Author(s)
  Zar PPK, Moroshita A, Hashimoto F, Sakao K, Fujii M, Wada K, Hou DX
- Journal Title
  
  J. Functional Foods
  
  Volume: 6 Pages: 523-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580176
[Journal Article] A genome-wide microarray highlights the anti-inflammatory genes targeted by oolong tea theasinensin A in macrophages2011
- Author(s)
  Chen J, Qin S, Xiao J, Tanigawa S, Uto T, Hashimoto F, Fujii M and Hou DX
- Journal Title
  
  Nutr. Cancer
  
  Volume: 63(7) Pages: 1064-1073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580176
[Journal Article] Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPSactivated mouse macrophages : molecular mechanisms and structure-activity relationship2007
- Author(s)
  Hou DX*, Masuzaki S, Hashimoto F, UtoT, Tanigawa S, Fujii M, Sakata Y
- Journal Title
  
  Arch. Biochem. Biophys. 460(1)
  
  Pages: 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580125
[Journal Article] Prodelphinidin B-4 3'-O-gallate, a tea polyphenol, is involved in the inhibition of COX-2 and iNOS via the downregulation of TAK1-NF-kappaB pathway.2007
- Author(s)
  Hou DX, Luo D, Tanigawa S, Hashimoto F, Uto T, Masuzaki S, Fujii M, Sakata Y.
- Journal Title
  
  Biochem Pharmacol. 74(5)
  
  Pages: 742-751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580125
[Journal Article] Prodelphinidin B-4 3'-O-gallate, a tea polyphenol, is involved in the inhibition of COX-2 and iNOS via the downregulation of TAK1-NF-kB pathway2007
- Author(s)
  Hou DX*, Dong Luo, Tanikawa S, HashimotoF, Uto T, Masuzaki S, Fujii M, SakataY
- Journal Title
  
  Biochem. Pyarm. 74
  
  Pages: 742-752
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580125
[Journal Article] Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPS-activated mouse macrophages : Molecular mechanisms and structure-activity relationship.2007
- Author(s)
  Hou DX, MasuzakiS, Hashimoto F, Uto T, Tanigawa S, Fujii M, Sakata Y.
- Journal Title
  
  Archives of Biochemistry and Biophysics 460
  
  Pages: 67-74
- Data Source
  KAKENHI-PROJECT-18580125
[Patent] トルコギキョウの新品種作出方法2014
- Inventor(s)
  橋本文雄、清水圭一、髙取由佳
- Industrial Property Rights Holder
  国立大学法人鹿児島大学、株式会社鹿児島TLO
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-03
- Acquisition Date
  2016-04-07
- Overseas
- Data Source
  KAKENHI-PROJECT-26450040
[Presentation] トルコギキョウの花弁の斑入りに関する研究2017
- Author(s)
  江上大貴，小畑舞，針原彩乃，福山達也，髙取由佳，清水圭一，橋本文雄
- Organizer
  植物色素研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07601
[Presentation] 近年のトルコギキョウ品種にみられる新奇な花冠形質の遺伝について2017
- Author(s)
  安永智希，加藤文俊，鮫島理沙，田代桃子，江上大貴，清水圭一，髙取由佳，草留大陸，橋本文雄
- Organizer
  園芸学会
- Data Source
  KAKENHI-PROJECT-16K07601
[Presentation] Anthocyanidin synthase (ANS) 遺伝子の多型がトルコギキョウ花弁のアントシアニン色素の蓄積に及ぼす影響2017
- Author(s)
  髙取由佳, 清水圭一, 橋本文雄
- Organizer
  園芸学会
- Data Source
  KAKENHI-PROJECT-16K07601
[Presentation] トルコギキョウにおける黄色花の遺伝様式2016
- Author(s)
  髙取由佳・清水圭一・橋本文雄
- Organizer
  園芸学会秋季大会、園芸学研究
- Place of Presentation
  名城大学（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-26450040
[Presentation] 鹿児島大学における花き研究の概要2016
- Author(s)
  橋本文雄
- Organizer
  農業開発総合センター・花き部・花き試験成績検討会ならびに試験課題検討会
- Place of Presentation
  農業開発総合センター（鹿児島県日置市）
- Invited
- Data Source
  KAKENHI-PROJECT-26450040
[Presentation] 野生種トルコギキョウを起源とする二重咲き花形の遺伝様式2015
- Author(s)
  高取由佳, 櫟本裕太郎, 清水圭一, 橋本文雄.
- Organizer
  園芸学会秋季大会, 園芸学研究
- Place of Presentation
  徳島大学（徳島県徳島市常三島キャンパス）
- Year and Date
  2015-09-27
- Data Source
  KAKENHI-PROJECT-26450040
[Presentation] Chemical Taxonomy of Tulip Cultivars by Tepal Anthocyanins2014
- Author(s)
  Fumio Hashimoto1, Masayoshi Nakayama, Toshiaki Tsuji, Osamu Urashima, Misae Taya-Kizu, Akiko Nagai, Keiichi Shimizu
- Organizer
  The XXVII International Conference on Polyphenols
- Place of Presentation
  Nagoya University, Japan
- Data Source
  KAKENHI-PROJECT-23580047
[Presentation] Chemosystematics of Tulips by tepal anthocyanins as phenetic markers2014
- Author(s)
  Fumio Hashimoto, Masayoshi Nakayama, et al.
- Organizer
  International Conference on Polyphenols
- Place of Presentation
  Nagoya
- Year and Date
  2014-09-03
- Data Source
  KAKENHI-PROJECT-23580047
[Presentation] Flavonoid 3',5'-hydroxylase (F3'5'H) 遺伝子の多型がトルコギキョウ花弁のアントシアニジン組成に及ぼす影響2014
- Author(s)
  高取由佳, 米澤徹, 前島理奈, 清水圭一, 橋本文雄
- Organizer
  園芸学会秋季大会
- Place of Presentation
  佐賀大学（佐賀県、佐賀市）
- Year and Date
  2014-09-28
- Data Source
  KAKENHI-PROJECT-26450040
[Presentation] Phenetics of tulip cultivars based on tepal anthocyanins2013
- Author(s)
  Hashimoto, F., Ju, X.T., Nakayama, M, et al.
- Organizer
  The 7^<th> International Workshop on Anthocyanins
- Place of Presentation
  Porto, Portugal
- Year and Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-23580047
[Presentation] Detection of a copigment to delphinidin 3-rutinoside responsible for deep-purple color of tulip flower by the cross-TLC method2013
- Author(s)
  Nakayama, M., Hashimoto, F
- Organizer
  The 7^<th> International Workshop on Anthocyanins
- Place of Presentation
  Porto, Portugal
- Year and Date
  2013-09-09
- Data Source
  KAKENHI-PROJECT-23580047
[Presentation] Detection of a copigment to delphinidin 3-rutinoside responsible for deep-purple color of tulip flower by the cross-TLC method2013
- Author(s)
  Nakayama, M., Hashimoto, F.
- Organizer
  The 7th International Workshop on Anthocyanins
- Place of Presentation
  Porto University, Portugal
- Data Source
  KAKENHI-PROJECT-23580047
[Presentation] Phenetics of tulip cultivars based on tepal anthocyanins2013
- Author(s)
  Hashimoto, F., Ju, X.T., Nakayama, M., Kurashige, Y., Tsuji, T., Urashima, O, Taya-Kizu, M., Nagai, A., Shimizu, K.
- Organizer
  The 7th International Workshop on Anthocyanins
- Place of Presentation
  Porto University, Portugal
- Data Source
  KAKENHI-PROJECT-23580047
[Presentation] Molecular basis for flavonoids: from gene expression profiling to molecule targeting2012
- Author(s)
  Hou DX*, Tanigawa S, Chen JH, Qin S You SX, Kumamoto T, Hashimoto F, He X, He JH
- Organizer
  13th Congress of the International Society for Ethnopharmacology
- Place of Presentation
  Graz, Austria
- Invited
- Data Source
  KAKENHI-PROJECT-23580176
[Presentation] Molecular basis for flavonoids : from gene expression profiling to molecule targeting2012
- Author(s)
  Hou DX, Tanigawa S, Chen JH, Qin S You SX, Kumamoto T, Hashimoto F, He X, He JH.
- Organizer
  13th Congress of the International Society for Ethnopharmacology
- Place of Presentation
  Graz, Austria
- Data Source
  KAKENHI-PROJECT-23580176

1. HOU De-xing (90305160)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. Shimizu Keiichi (30305164)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. FUJII Makoto (70041655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. NAKAYAMA Masayoshi (40237475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. KASHIWADA Yoshiki (30169429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NATAO Tsuneatsu (90180455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OKABE Hikaru (10078678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Noda Naonobu (10455313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 李國雄

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. LEE Kuo-Hsiung

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 季國雄

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HASHIMOTO Fumio 橋本 文雄

Research Projects

Research Products

Co-Researchers

Flower color modification through interaction between B-ring glycosylated delphinidins and flavonols in Eustoma grandiflorum

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis and utilization of transposon isolated from a variegated flower line in Eustoma grandiflorumm

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Breeding method for creating new types of flower colors of EustomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemosystematic of Tulips based on tepal anthocyanins as phenetic markersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of the molecular targets for bioactive anthocyanins: MAP kinase as direct targets

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Signaling pathways for the inhibition of cell transformation by anthocyanins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Colaborative Research on Anti-HIV Triterpenoids

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規抗脂血症用薬"26-aminocholesterol"合成法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Efficiency of Hand-thinning in Apple Cultivars with Varying Degrees of Fruit Abscission2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] 野生種トルコギキョウを起源とする二重咲き花形の遺伝様式2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea2014

Author(s)

Journal Title

Data Source

[Journal Article] Anti-inflammatory effects and molecular mechanisms of loquat (Eriobotrya japonica) tea2014

Author(s)

Journal Title

Data Source

[Journal Article] A genome-wide microarray highlights the anti-inflammatory genes targeted by oolong tea theasinensin A in macrophages2011

Author(s)

Journal Title

Data Source

[Journal Article] Green tea proanthocyanidins inhibit cyclooxygenase-2 expression in LPSactivated mouse macrophages : molecular mechanisms and structure-activity relationship2007

Author(s)

Journal Title

HASHIMOTO Fumio 橋本文雄

[Presentation] Anthocyanidin synthase (ANS) 遺伝子の多型がトルコギキョウ花弁のアントシアニン色素の蓄積に及ぼす影響2017