OMURA Motoko 大村素子

Researcher Number	70244506
Affiliation (based on the past Project Information) *help	2012: 横浜市立大学, 医学(系)研究科(研究院), その他 2012: 横浜市立大学, 大学院・医学研究科, 客員准教授 2011: 横浜市立大学, 医学研究科, 客員准教授 2009 – 2011: Yokohama City University, 医学部, 准教授 2008: Yokohama City University, 医学部, 助教 … More 2006: Yokohama City University, School of Medicine, Assistant Professor 2006: Yokohama City University, Hospital, assistant 2003 – 2006: 横浜市立大学, 医学部, 助手 2005: 横浜市立大学, 附属病院, 助手 2002 – 2004: 横浜市立大学, 医学部附属病院, 助手 2001: 横浜市立大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Radiation science / Radiation science Except Principal Investigator Radiation science / Respiratory organ internal medicine
Keywords	Principal Investigator 放射線治療 / VEGF / HIF / bcl-2 / radiation / spheroid siRNA / スフェロイド / si-RNA / 放射線増感剤 / spheroid … More / siRNA / 放射線 / 血漿DNA / 放射線治療血漿DNA / 定量的PCR法 / 腫瘍 / 分子生物学 / 腫瘍マーカー / 核酸 / 癌 / アポトーシス / アンチセンス / 放射線照射 … More Except Principal Investigator 放射線感受性 / アポトーシス / siRNA / radiation sensitivity / DNase II / gene knock down / DNAチップ / bcl2遺伝子 / hSMG1遺伝子 / 遺伝子ノックダウン / apoptosis / アネキシンV / ソノポレーション / エレクトロポレーション / PCR法 / 線量分布 / ウエスタンブロット法 / TUNEL法 / ^<67>Ga-DTPA-Annexin V / 遺伝子導入 / DNaseII / OLEAMIDE / GAP JUNCTION / IONIZING RADIATION / CULTURED CELLS / 薬剤 / 細胞間接着因子 / olemide / 感受性 / connexin43 / UMRC-6 / MDCK / oleamide / ギャップジャンクション / 細胞間接着 / γ線(電離放射線) / miRNA / microRNA / 293T細胞 / poly-A-polymelase / 99mTc / 遺伝子発現イメージング / SPECT / PET / BrdUrd / 免疫染色 / 肺癌 / SQ5細胞株 / A549細胞株 / 同所移植 Less

The study of application of microRNA to radiation therapy
- Principal Investigator
  
  ZENDA Sadamoto
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  National Cancer Center Japan
Study on gene expression imaging in the living body using radioilabelled siRNA
- Principal Investigator
  
  NAKAGAMI Yoshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University
同所移植肺腫瘍の特性解析
- Principal Investigator
  
  KANG Yun
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yokohama City University
Quantification of cell-free DNA in the plasma during radiation therapyPrincipal Investigator
- Principal Investigator
  
  OMURA Motoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University
The research about the application of RNAi phenomenon to radiation therapy : using hSMG1-siRNA
- Principal Investigator
  
  NAKAGAMI Yoshihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University
Application of tumor model multicellular spheroids for combination therapy of siRNA targeting HIF-VEGF and radicationPrincipal Investigator
- Principal Investigator
  
  OMURA Motoko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University
放射線治療患者の血中癌特異的DNA/RNAの経時的定量による治療感受性の早期判定Principal Investigator
- Principal Investigator
  
  大村素子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University
INVESTIGATION OF EFFECT OF THE CELL-CELL CONTACT INHIBITION ON RADIATION SENSITIVITY AND DETERMINATION OF THE RELATING FACTORS
- Principal Investigator
  
  INOUE Tomio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University
The basic research about gene-radiation therapy using DNase II gene
- Principal Investigator
  
  NAKAGAMI Yoshihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University
bcl-2を標的とした薬剤の放射線増感効果Principal Investigator
- Principal Investigator
  
  大村素子
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Radiation science
- Research Institution
  Yokohama City University

All 2010 2009 2006

All Journal Article Presentation

[Journal Article] Proliferation of human lung cancer growing in orthotopic transplantation mouse model2010
- Author(s)
  Yun Kang, Motoko Omura, Chumpol Theeraladanon, Akiko Suzuki, Takashi Oka, Yoshihiro Nakagami, Atsushi Suzuki, Yoji Nagashima, Tomio Inoue
- Journal Title
  
  Experimental and Therapeutic Medicine 1
  
  Pages: 471-475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590931
[Journal Article] Quantification of circulating cell-free DNA in the plasma of cancer patients during radiation therapy2009
- Author(s)
  Chao Cheng, Motoko Omura-Minamisawa, Yun Kang, Takamitsu Hara, Izumi Koike and Tomio Inoue
- Journal Title
  
  Cancer Science
  
  Volume: 100(2) Pages: 303-309
- NAID
  10025142537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591499
[Journal Article] Quantification of circulating cell-free DNA in the plasma of cancer patients during radiation therapy2009
- Author(s)
  Cheng, C. Omura-Minamisawa, M. Kang, Y. Hara, T. Koike, I. Inoue, T.
- Journal Title
  
  Cancer Science 100
  
  Pages: 303-309
- NAID
  10025142537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591499
[Presentation] Tumor specific cell-free DNA in plasma of tumor bearing mice reflects antitumor effects of radiation2010
- Author(s)
  Chao Cheng, Motoko Omura, Masahiro Natsuhori, Yun Kang, Takamitsu Hara, Izumi Koike, Masaharu Hata, Tomio Inoue
- Organizer
  American Society for Radiation Oncology 52th Annual Meeeting
- Place of Presentation
  アメリカ、サンディエゴ
- Year and Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-20591499
[Presentation] 腫瘍に対する放射線治療効果を血漿中腫瘍細胞DNAの経時的定量によって判定する2010
- Author(s)
  程超, 大村素子, 他
- Organizer
  日本放射線腫瘍学会第22回学術大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-20591499
[Presentation] Tumor Specific Cell-free DNA in the Plasma is a Marker of the Tumor Response to Radiation in an Experimental Mouse Model2010
- Author(s)
  程超、大村素子, 他
- Organizer
  米国放射線腫瘍学会第52回学術大会
- Place of Presentation
  アメリカサンディエゴ
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-20591499
[Presentation] N USEFUL ORTHOTOPIC TRANSPLANTATION ANIMAL MODEL FOR HUMAN LUNG CANCER RESEARCH2009
- Author(s)
  Y.Kang, M.Omura, A.Suzuki N.Takahashi, T.Oka, Y.Nakagami, C.Cheng, Y.Nagashima, T.Inoue
- Organizer
  Annual congress of the European Association of Nuclear medicine
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20590931
[Presentation] 腫瘍に対する放射線治療効果を血漿中腫瘍細胞DNAの経時的定量によって判定する2009
- Author(s)
  程超, 大村素子, 夏堀雅宏, 康芸, 原孝光, 小池泉, 幡多政治, 井上登美夫
- Organizer
  日本放射線腫瘍学会第22回学術大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591499
[Presentation] Tomio Inoue siRNA Implicated for Tumor Therapy to Enhance the Radiation Effect on Tumor Cells2006
- Author(s)
  Yuefen Zou, Motoko Omura
- Organizer
  Japanease Society for Therapeutic Radiation and Oncology, 21st Annual meeting
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591285

1. INOUE Tomio (80134295)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
2. NAKAGAMI Yoshihiro (80347301)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. KANG Yun (60332607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. OGINO Ichiro (20275035)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HATA Masaharu (60285145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. KOIKE Izumi (00295495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. ICHIKAWA Yasushi (70254208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MITUSDOU Kenji (70303641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ZENDA Sadamoto (30466198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HARA Takamitsu (70464542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. チュンポールティララダノン (20448682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. CHENG Chao

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. NATSUHORI Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

OMURA Motoko 大村 素子

Research Projects

Research Products

Co-Researchers

The study of application of microRNA to radiation therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on gene expression imaging in the living body using radioilabelled siRNA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

同所移植肺腫瘍の特性解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Quantification of cell-free DNA in the plasma during radiation therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The research about the application of RNAi phenomenon to radiation therapy : using hSMG1-siRNA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of tumor model multicellular spheroids for combination therapy of siRNA targeting HIF-VEGF and radicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

放射線治療患者の血中癌特異的DNA/RNAの経時的定量による治療感受性の早期判定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

INVESTIGATION OF EFFECT OF THE CELL-CELL CONTACT INHIBITION ON RADIATION SENSITIVITY AND DETERMINATION OF THE RELATING FACTORS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The basic research about gene-radiation therapy using DNase II gene

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

bcl-2を標的とした薬剤の放射線増感効果Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Proliferation of human lung cancer growing in orthotopic transplantation mouse model2010

Author(s)

Journal Title

Data Source

[Journal Article] Quantification of circulating cell-free DNA in the plasma of cancer patients during radiation therapy2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Quantification of circulating cell-free DNA in the plasma of cancer patients during radiation therapy2009

Author(s)

Journal Title

NAID

Data Source

[Presentation] Tumor specific cell-free DNA in plasma of tumor bearing mice reflects antitumor effects of radiation2010

Author(s)

OMURA Motoko 大村素子