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ITOH Yoshito  伊藤 義人

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… Alternative Names

伊藤 義人  イトウ ヨシト

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Researcher Number 70244613
Other IDs
Affiliation (Current) 2022: 京都府立医科大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help 2022: 京都府立医科大学, 医学(系)研究科(研究院), 教授
2012 – 2017: 京都府立医科大学, 医学(系)研究科(研究院), 教授
2015: 京都府立医科大学, 大学院医学研究科, 教授
2008 – 2010: Kyoto Prefectural University of Medicine, 医学研究科, 准教授
2003 – 2007: 京都府立医科大学, 医学研究科, 講師 … More
2003: 京都府立医科大学, 医学部研究科, 講師
1998 – 2002: 京都府立医科大学, 医学部, 助手
1993 – 1996: 京都府立医科大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Gastroenterology / Gastroenterology
Keywords
Principal Investigator
肝炎 / ケモカインレセプター / ケモカイン / 肝癌 / M-CSF / 肝細胞癌 / 脂肪肝炎 / Apg-2 / chemokine receptor / 増殖 … More / MAPK / 転移 / HCC / growth / 炎症性サイトカイン / インターフェロンα / c-cケモカイン / IP-10 / TNF receptor / IL-2 receptor / 肝臓学 / 遺伝子増幅領域 / マイクロアレイ / 遺伝子幅域 / 熱ショック蛋白 / APG-2 / 部分肝切除 / 肝細胞がん / CXCケモカイン / ELRモチーフ / 肝疾患 / CXC chemokine / ELR-motif / liver disease / ヘパラナーゼ / 肝癌細胞株 / heparanase / hepatitis / hepatoma cell lines / Chemokine / Chemokine Receptor / 肝がん / シグナル伝達 / chemokine / metastasis / signal transduction / 分子シャペロン / 細胞周期 / ユビキチン化 / 非アルコール性脂肪肝炎 … More
Except Principal Investigator
レトロウイルス / 肝癌細胞株 / 肝細胞 / 肝癌 / B型肝炎 / B型肝炎ウイルス / 肝発癌 / レトロウイルスベクター / LTR / 肝臓 / ベクター / 癌遺伝子 / レトロウイルs / microRNA / micro RNA / DGAT / 炎症 / 肝脂肪化 / 肝線維化 / 遺伝子組み込み / ラミブジン / YMDD変異ウイルス / C型肝炎ウイルス / インターフェロン / リバビリン / HCVdynamics / C型肝炎 / C型慢性肝炎 / HBV / 肝発癌抑制 / Alu-PCR / hepatitis B virus / integration / lamivudine / YMDD motif mutant / hepatitis C virus / interferon / ribavitin / hepatocarcinogenesis / 骨髄細胞 / インシュレータ / メチル化 / インシュレーター / retrovirus / hepatocyte / bone marrow cell / insulator / methylation / 脂肪肝炎 / PD-1 / 脂肪肝 / 獲得免疫 / 免疫老化 Less
  • Research Projects

    (19 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (5 People)
  •  Significance of Apg-2 in human NAFLDPrincipal Investigator

    • Principal Investigator
      伊藤 義人
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The role of Apg-2 in liver steatosis and carcinogenesisPrincipal Investigator

    • Principal Investigator
      Itoh Yoshito
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Examination about the association between intrahepatic immunogenicity and the expression of regulatory molecules on hepatic T cells in mouse NASH model.

    • Principal Investigator
      YAMAGUCHI KANJI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The role of Apg-2 in hepatocarcinogenesis and regenerationPrincipal Investigator

    • Principal Investigator
      ITOH Yoshito
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Analysis of newly recognized amplified region in 1q21p in hepatocellular carcinomaPrincipal Investigator

    • Principal Investigator
      ITOH Yoshito
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The effect of DGAT on liver steatosis, fibrosis and carcinogenesis in murine NASH models.

    • Principal Investigator
      YAMAGUCHI Kanji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Investigation for the mechanisms of metastasis and growth of HCC via chemokine receptorsPrincipal Investigator

    • Principal Investigator
      ITOH Yoshito
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  B型肝炎ウイルスのコードするmicroRNAの検索

    • Principal Investigator
      岡上 武
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  HCV core蛋白を標的とした新たな遺伝子治療戦略の可能性

    • Principal Investigator
      岡上 武
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Analysis of chemokine/chemokine system involoved in the growth of human hepatocellular carcinomaPrincipal Investigator

    • Principal Investigator
      ITOH Yoshito
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Gene transfer to hematopoietic stem cells by a newly-designed retroviral vectors and expression of transgenes in the liver

    • Principal Investigator
      OKANOUE Takeshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Expression of heparanase in the hepatic tissue of hepatitis patients and its clinical significancePrincipal Investigator

    • Principal Investigator
      ITOH Yoshito
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  肝細胞で高発現する新しいレトロウイルスベクターの開発

    • Principal Investigator
      OKANOUE Takeshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Treatment of chronic hepatitis and analysis of HBV integration for the purpose of prevention of hepatocellular carcinoma

    • Principal Investigator
      OKANOUE Takeshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Expression of CXC chemokines lacking ELR-motif in liver diseases and its clinical significancePrincipal Investigator

    • Principal Investigator
      ITOH Yoshito
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicune
  •  C型肝炎での炎症性サイトカインの意義Principal Investigator

    • Principal Investigator
      伊藤 義人
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  肝炎患者でのC-Cケモカインの意義Principal Investigator

    • Principal Investigator
      伊藤 義人
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  肝炎患者末梢血の内因性インターフェロンαによる炎症性サイトカイン産生の制御Principal Investigator

    • Principal Investigator
      伊藤 義人
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  肝炎患者の肝組織中と末梢血探求におけるマクロファージコロニー刺激因子の臨床的意義Principal Investigator

    • Principal Investigator
      伊藤 義人
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2017 2016 2015 2011 2010 2009 2008 2004

All Journal Article Presentation

  • [Journal Article] High expression of p300 in HCC predicts shortened overall survival in association with enhanced epithelial mesenchymal transition of HCC cells2011

    • Author(s)
      Yokomizo C, Yamaguchi K, Itoh Y, Nishimura T, Minami M, Yasui K, Mitsuyoshi H, tochiki N, Fujii H, Nakajima T, Umemura A, Okanoue T, Yoshikawa T
    • Journal Title

      Cancer Lett

      Volume: 310 Pages: 140-147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590790
  • [Journal Article] Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice.2010

    • Author(s)
      Yamaguchi K, Itoh Y, Yokomizo C, Nishimura T, Niimi T, Fujii H, Okanoue T, Yoshikawa T.
    • Journal Title

      Lab Invest. 90(8)

      Pages: 1169-1178

    • Data Source
      KAKENHI-PROJECT-20790503
  • [Journal Article] Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma after a sustained response to the interferon therapy2004

    • Author(s)
      Makiyama A, Itoh Y, Kasahara A, et al.
    • Journal Title

      Cancer 101

      Pages: 1616-1622

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590674
  • [Journal Article] Chemokine CCL20 Enhances the growth of HuH7 cells via Phosphorylation of p44/42 MAPK in vitro.2004

    • Author(s)
      Fujii H, Itoh Y, Yamaguchi K, et al.
    • Journal Title

      Biochem Biophys Res Commun 322

      Pages: 1052-1058

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590674
  • [Journal Article] Engineered long terminal repeats of retroviral vectors enhance transgene expression in hepatocytes in vitro and in vivo.2004

    • Author(s)
      Yamaguchi K, Itoh K, Ohnishi N, et al.
    • Journal Title

      Mol Ther 8

      Pages: 796-803

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590674
  • [Presentation] Apg-2 plays an important role in hepatic steatosis2017

    • Author(s)
      Yamaguchi Kanji, Ishiba Hiroshi, Seko Yuya, Umemura Atsushi, Itoh Yoshito
    • Organizer
      第1回ICFL The 1st International Conference on Fatty Liver
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09018
  • [Presentation] 分子シャペロンApg-2をターゲットにした肝脂肪化治療戦略2017

    • Author(s)
      山口寛二、石破博、伊藤義人
    • Organizer
      第53回日本肝臓学会総会(広島)、PD2-14(追加発言)
    • Data Source
      KAKENHI-PROJECT-15K09018
  • [Presentation] Apg2 is a key determinant of hepatic steatosis by regulating AMPK activity2016

    • Author(s)
      Hiroshi Ishiba, Kanji Yamaguchi, Itoh Yoshito
    • Organizer
      The Liver Meeting® 2016 第67回米国肝臓学会
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-15K09018
  • [Presentation] マウス脂肪肝炎におけるPD-1陽性T細胞の発現解析2015

    • Author(s)
      山口寛二、岡嶋亮、伊藤義人.
    • Organizer
      第51回肝臓学会総会
    • Place of Presentation
      熊本
    • Year and Date
      2015-05-22
    • Data Source
      KAKENHI-PROJECT-25461005
  • [Presentation] マウス脂肪肝炎における Heat shock蛋白Apg-2の役割についての検討2015

    • Author(s)
      山口寛二、石破博、伊藤義人
    • Organizer
      日本肝臓学会西部会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PROJECT-15K09018
  • [Presentation] Two different aspects of PD-1 expression on intrahepatic CD4+ and CD8+ T cells in a High Fat High Cholesterol Diet-induced murine NASH.2015

    • Author(s)
      Kanji Yamaguchi, Akira Okajima, Yuya Seko, Hiroshi Ishiba, Hiroyoshi Taketani, Atsushi Umemura, Taichiro Nishikawa, Yoshio Sumida, Hironori Mitsuyoshi, Kohichiroh Yasui, Takeshi Okanoue, Yoshito Itoh.
    • Organizer
      第66回AASLD
    • Place of Presentation
      San Francisco
    • Year and Date
      2015-11-16
    • Data Source
      KAKENHI-PROJECT-25461005
  • [Presentation] High expression of P300 in HCC is associated with EMT-like phenotypic change and cyclin D1/beta-catenin dependent growth of HCC cells which may underlie poor prognosis of the patients2011

    • Author(s)
      Yokomizo C, Yamaguchi K, Nishimura T, N Tochiki, Fujii H, Nakajima T, Umemura A, Okanoue T, Itoh Y
    • Organizer
      62th Annual Meeting of the American Association for the Study of Liver Disease(AASLD)
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-20590790
  • [Presentation] 細胞癌におけるtranscriptional cofactor P300の発現とその臨床的意義2011

    • Author(s)
      横溝千尋、山口寛二、新美敏久、西村健、藤井秀樹、吉川敏一、伊藤義人
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590790
  • [Presentation] High Expression of A Transcriptional Cofactor P300 in HCC Down-Regulates E-Cadherin, Promotes Tumor Invasion, And Predicts Shortened Overall Survival Of HCC Patients2010

    • Author(s)
      Yokomizo C, Itoh Y, Yamaguchi k, Nishimura T, Okanoue T, Yoshikawa T
    • Organizer
      61th Annual Meeting of the American Association for the Study of Liver Disease(AASLD)
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-20590790
  • [Presentation] マウス脂肪肝、脂肪性肝炎モデルにおけるIL-6と肝脂肪化の関係について2009

    • Author(s)
      山口寛二、伊藤義人、横溝千尋、西村健、新美敏久、岡上武、吉川敏一
    • Organizer
      第38回日本肝臓学会西部会
    • Place of Presentation
      鳥取
    • Year and Date
      2009-12-04
    • Data Source
      KAKENHI-PROJECT-20790503
  • [Presentation] Inhibiting Interleukin-6/GP130 Signaling in Hepatocytes Worsens Hepatic Steatosis and Fibrosis in Lean and db/db mice Fed Methionine Choline Deficient Diets.2008

    • Author(s)
      Kanji Yamaguchi, Yoshito Itoh, Toshihisa Niimi, Norihiro Mitsuyoshi, Koichiro Yasui, Masahito Minami, Masaki Iwai, Okanoue Takeshi, Toshikazu Yoshikawa
    • Organizer
      第59回アメリカ肝臓病学会(ポスター)
    • Place of Presentation
      サンフランシスコアメリカ
    • Year and Date
      2008-11-03
    • Data Source
      KAKENHI-PROJECT-20790503
  • [Presentation] マウス脂肪性肝炎モデルにおけるDGAT ASOの効果について2008

    • Author(s)
      山口寛二、伊藤義人、横溝千尋、西村健、新美敏久、岡上武、吉川敏一
    • Organizer
      第44回日本肝臓学会総会ワークショップ
    • Place of Presentation
      愛媛
    • Year and Date
      2008-06-04
    • Data Source
      KAKENHI-PROJECT-20790503
  • 1.  OKANOUE Takeshi (20150568)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  ITOH Katsuhiko (90281097)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 3.  YAMAGUCHI Kanji (50381950)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 4.  Fujita Jun (50173430)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YASUI Kohichiroh (30323695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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