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Takeda Mariko  武田 真莉子

… Alternative Names

武田 真莉子  タケダ マリコ

TAKEDA Mariko  武田 真莉子

MORISHITA Mariko  森下 まり子

Less
Researcher Number 70257096
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-3512-4885
External Links
Affiliation (Current) 2025: 神戸学院大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2016 – 2023: 神戸学院大学, 薬学部, 教授
2012 – 2013: 神戸学院大学, 薬学部, 教授
2009 – 2011: Hoshi University, 薬学部, 准教授
2008: Hoshi University, 星薬科大学・薬学部, 准教授
2006 – 2007: 星薬科大学, 薬学部, 准教授
2005: 星薬科大学, 薬学部, 助教授
Review Section/Research Field
Principal Investigator
Physical pharmacy / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Except Principal Investigator
Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
Keywords
Principal Investigator
バイオ医薬 / インスリン / バイオアベイラビリティ / 吸収改善 / 細胞膜透過ペプチド / 薬物送達システム / 経口投与 / バイオ薬物 / 吸収促進 / ドラッグデリバリー … More / 経口製剤化 / ワクチン / ウルトラファインバブル / in vitro予測モデル / 経口バイオアベイラビリティ予測 / iPS細胞由来腸管細胞 / 中分子薬物 / iPS細胞由来腸管上皮細胞 / 生体膜膜透過性 / in vitro-in vivo相関 / キャリア / 生体膜透過機構 / ヒト iPS細胞由来腸管上皮細胞 / 小腸吸収性予測 / IVIVC / In vitro models / Caco-2細胞単層膜 / ヒトiPS細胞由来小腸上皮細胞 / 生体膜透過性評価 / ペプチド薬物 / 吸収促進剤 / Caco-2 細胞 / iPS細胞由来小腸上皮細胞 / 生体膜透過性 / 経口吸収予測 / 消化管吸収 / 経口製剤 / 難吸収性薬物 / トリプトファン / アルギニン / 生体膜透過 / Hvdrogel / Absorption improvement / Cell penetrating peptide / Bioavailability / Oral administration / Biodrug / Insulin / Drug delivery system / バイオアベイラビリテイ / ハイドロゲル / 細胞膜透過性ペプチド / バイオアベリラビリティ / 経鼻吸収 / 経口吸収 / ペネトラチン / 非侵襲的投与経路 / Caco-2細胞 / 機能性ペプチド … More
Except Principal Investigator
Nose-to-Brain送達法 / Exendin-4 / 血管周囲腔 / 嗅粘膜 / 認知症治療 / インスリン / アミロイドβ / 認知症 / アルツハイマー病 / 細胞膜透過ペプチド / 抗体薬 / ペプチド薬物 / 脳内デリバリー / 経鼻投与 Less
  • Research Projects

    (7 results)
  • Research Products

    (237 results)
  • Co-Researchers

    (4 People)
  •  Challenging research to development oral vaccines (biopharmaceuticals) with innovative material ultrafine bubblesPrincipal Investigator

    • Principal Investigator
      武田 真莉子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Kobe Gakuin University
  •  Investigation of prediction of oral absorption of biopharmaceuticals and high-functional DDS using iPS cell-derived intestinal cellsPrincipal Investigator

    • Principal Investigator
      Takeda Mariko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Kobe Gakuin University
  •  Establishment of Nose-to-Brain Delivery Strategy for Treatment of Dementia Based on Pharmacokinetic and Therapeutic Analyses

    • Principal Investigator
      Kamei Noriyasu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Kobe Gakuin University
  •  Establishment of innovative biomembrane permeation boosting technology aiming for early clinical developmentPrincipal Investigator

    • Principal Investigator
      Takeda Mariko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kobe Gakuin University
  •  Development of non-invasive delivery of biopharmaceuticals equipped with novel membrane permeation technology and their translational researchPrincipal Investigator

    • Principal Investigator
      TAKEDA Mariko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kobe Gakuin University
      Hoshi University
  •  Development research of next generation type of non-invasive DDS using delivery carrierPrincipal Investigator

    • Principal Investigator
      MORISHITA Mariko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Hoshi University
  •  Development of oral delivery system for peptide/protein drugs, such as insulinPrincipal Investigator

    • Principal Investigator
      MORISHITA Mariko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Hoshi University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] 認知症を治癒する革新的創薬に向けたペプチド薬物脳内送達法の開発, ペプチド創薬の最前線2019

    • Author(s)
      亀井敬泰, 武田真莉子
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Book] 医療・診断をささえるペプチド科学2017

    • Author(s)
      武田真莉子
    • Total Pages
      315
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Book] ペプチド医薬の最前線2012

    • Author(s)
      亀井敬泰, 武田(森下)真莉子
    • Total Pages
      240
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Book] The DDS2012

    • Author(s)
      森下真莉子
    • Total Pages
      229
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Book] ペプチド医薬の最前線2012

    • Author(s)
      亀井敬泰,武田(森下)真莉子(分担執筆)
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Book] The DDS2012

    • Author(s)
      森下真莉子(分担執筆)
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Book] ペプチド・タンパク性医薬品の新規DDS製剤の開発と応用2011

    • Author(s)
      亀井敬泰,森下真莉子(分担執筆)
    • Publisher
      メディカルドウ
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Book] バイオ医薬品の処方設計と開発技術2011

    • Author(s)
      森下真莉子(監修、および分担執筆)
    • Total Pages
      245
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Book] 次世代バイオ医薬品の処方設計と開発技術2011

    • Author(s)
      森下真莉子(監修,分担執筆)
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Book] ペプチド・タンパク性医薬品の新規DDS製剤の開発と応用2011

    • Author(s)
      亀井敬泰、森下真莉子(分担執筆)
    • Total Pages
      280
    • Publisher
      メディカルドウ
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Book] 薬物の消化管吸収予測研究の最前線2010

    • Author(s)
      森下真莉子(共著)
    • Total Pages
      130
    • Publisher
      メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] 薬物の消化管吸収予測研究の最前線2010

    • Author(s)
      森下真莉子(編集,共著)
    • Total Pages
      130
    • Publisher
      メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] Biodrug Delivery Systems : Fundamentals, Applications and Clinical Development2009

    • Author(s)
      M.Morishita, K.Park, eds.
    • Total Pages
      471
    • Publisher
      Informa Healthcare
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] Applications and Clinical Development(Biodrug Delivery Systems : Fundamentals)2009

    • Author(s)
      M.Morishita, K.Park(編集,共著)
    • Total Pages
      471
    • Publisher
      Informa Healthcare
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] 薬物送達システム(DDS)の必要性、放出制御型製剤、『薬剤学』2008

    • Author(s)
      分担執筆 : 森下真莉子
    • Total Pages
      226
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] 薬剤学(薬物送達システム(DDS)の必要性、放出制御型製剤)2008

    • Author(s)
      森下真莉子(共著)
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] 分子薬物動態学(ドラッグデリバリーシステム:標的指向化(ターゲティング)の定量的解析)2008

    • Author(s)
      森下真莉子(共著)
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] 機能性DDSキャリアの製剤設計(機能性DDSキャリアの応用・実用化研究、細胞膜透過性ペプチドによるバイオ薬物の消化管吸収促進)2008

    • Author(s)
      森下真莉子(共著)
    • Publisher
      シーエムシー
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] 機能性DDSキャリアの応用・実用化研究、細胞膜透過性ペプチドによるバイオ薬物の消化管吸収促進、『機能性DDSキャリアの製剤設計』2008

    • Author(s)
      分担執筆 : 森下真莉子
    • Total Pages
      321
    • Publisher
      シーエムシー
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] ドラッグデリバリーシステム : 標的指向化(ターゲティング)の定量的解析、『分子薬物動態学』2008

    • Author(s)
      分担執筆 : 森下真莉子
    • Total Pages
      690
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Book] 最新創薬学2007:薬物動態学特性の解析は創薬のキーワード2007

    • Author(s)
      森下 真莉子, 共著
    • Publisher
      メディカルドゥ
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Book] 最新創薬学2007:薬物動態学特性の解析は創薬のキーワード2007

    • Author(s)
      森下 真莉子共著
    • Total Pages
      308
    • Publisher
      メディカルドゥ
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Effect of orally ingested water containing H2-filled ultrafine bubbles (UFBs) on ethanol-induced oxidative stress in rats2024

    • Author(s)
      Morishita R, Onishi A, Oya M, Karashima H, Mori M, Kawatani Y, Kamei N, Takeda-Morishita M
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K18566
  • [Journal Article] Evaluation of function and features of human induced pluripotent stem cell-derived small intestinal epithelial cells for analyzing peptide drug intestinal absorption profiles2023

    • Author(s)
      Mai Itagaki, Noriyasu Kamei, Mariko Takeda-Morishita
    • Journal Title

      Journal of Pharmaceutical Science

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07005
  • [Journal Article] Therapeutic effects of anti-amyloid β antibody after intravenous injection and efficient nose-to-brain delivery in Alzheimer’s disease mouse model2022

    • Author(s)
      Kamei Noriyasu、Hashimoto Ayaka、Tanaka Erina、Murata Kaho、Yamaguchi Maika、Yokoyama Natsuki、Kato Masahiro、Oki Keisuke、Saito Takashi、Saido Takaomi C.、Takeda-Morishita Mariko
    • Journal Title

      Drug Delivery and Translational Research

      Volume: In press Issue: 11 Pages: 2667-2677

    • DOI

      10.1007/s13346-022-01117-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Journal Article] Investigation of the Transport Pathways Associated with Enhanced Brain Delivery of Peptide Drugs by Intranasal Coadministration with Penetratin2021

    • Author(s)
      Kamei Noriyasu、Suwabe Susumu、Arime Kenji、Bando Hidemi、Murata Kaho、Yamaguchi Maika、Yokoyama Natsuki、Tanaka Erina、Hashimoto Ayaka、Kanazawa Takanori、Ago Yukio、Takeda-Morishita Mariko
    • Journal Title

      Pharmaceutics

      Volume: 13 Issue: 11 Pages: 1745-1745

    • DOI

      10.3390/pharmaceutics13111745

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07032, KAKENHI-PROJECT-20H04537
  • [Journal Article] Nose-to-Brain薬物送達効率を向上させる粘膜透過促進戦略2020

    • Author(s)
      亀井敬泰, 武田真莉子
    • Journal Title

      MEDCHEM NEWS

      Volume: 30 Pages: 25-29

    • NAID

      130008033683

    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Journal Article] Systemic and brain delivery of leptin via intranasal coadministration with cell-penetrating peptides and its therapeutic potential for obesity2020

    • Author(s)
      Khafagy El-Sayed、Kamei Noriyasu、Fujiwara Yui、Okumura Haruka、Yuasa Teruyo、Kato Masahiro、Arime Kenji、Nonomura Anna、Ogino Hideyuki、Hirano Serena、Sugano Sayaka、Takeda-Morishita Mariko
    • Journal Title

      Journal of Controlled Release

      Volume: 319 Pages: 397-406

    • DOI

      10.1016/j.jconrel.2020.01.016

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Journal Article] Nose-to-Brain経路を利用したペプチド薬物送達法:認知症治療薬の開発に向けて2019

    • Author(s)
      亀井敬泰, 武田真莉子
    • Journal Title

      Drug Delivery System

      Volume: 34 Pages: 360-367

    • NAID

      130007801751

    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Journal Article] Combination Strategy with Complexation Hydrogels and Cell-Penetrating Peptides for Oral Delivery of Insulin2018

    • Author(s)
      Y. Fukuoka, E. S. Khafagy, T. Goto, N. Kamei, K. Takayama, N. A. Peppas, M. Takeda-Morishita
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 41 Issue: 5 Pages: 811-814

    • DOI

      10.1248/bpb.b17-00951

    • NAID

      130006730708

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2018-05-01
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08252, KAKENHI-PROJECT-16K08211
  • [Journal Article] Exploration of the Key Factors for Optimizing the <i>in Vivo</i> Oral Delivery of Insulin by Using a Noncovalent Strategy with Cell-Penetrating Peptides2018

    • Author(s)
      Kamei N, Shigei C, Hasegawa R, Takeda-Morishita M
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 41 Issue: 2 Pages: 239-246

    • DOI

      10.1248/bpb.b17-00798

    • NAID

      130006329268

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Journal Article] Hydrophobic Amino Acid Tryptophan Shows Promise as a Potential Absorption Enhancer for Oral Delivery of Biopharmaceuticals2018

    • Author(s)
      Kamei N, Tamiwa H, Miyata M, Haruna Y, Matsumura K, Ogino H, Hirano S, Higashiyama K, Takeda-Morishita M
    • Journal Title

      Pharmaceutics

      Volume: 10 Issue: 4 Pages: 182-202

    • DOI

      10.3390/pharmaceutics10040182

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Journal Article] Potential of Single Cationic Amino Acid Molecule “Arginine” for Stimulating Oral Absorption of Insulin2017

    • Author(s)
      Noriyasu Kamei, El-Sayed Khafagy, Jun Hirose, Mariko Takeda-Morishita
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 521 Issue: 1-2 Pages: 176-183

    • DOI

      10.1016/j.ijpharm.2017.01.066

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Journal Article] One-month subchronic toxicity study of cell-penetrating peptides on insulin nasal delivery in rats2013

    • Author(s)
      E.S. Khafagy, N. Kamei, E. Nielsen, R. Nishio and M. Takeda-Morishita
    • Journal Title

      European Journal of Pharmaceutics and Biopharmaceutics

      Volume: 85 Pages: 736-741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] バイオ医薬品の非注射製剤の現状と開発動向2013

    • Author(s)
      武田真莉子
    • Journal Title

      薬剤学

      Volume: 73 Pages: 56-62

    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Non-invasive insulin delivery: the great potential of cell-penetrating peptides2013

    • Author(s)
      Kamei N, Nielsen EJB, Khafagy El-S, Takeda-Morishita M
    • Journal Title

      Ther. Deliv.

      Volume: 73 Pages: 315-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Non-invasive insulin delivery: the great potential of cell-penetrating peptides2013

    • Author(s)
      N. Kamei, E. Nielsen, El-S. Khafagy, M. Takeda-Morishita
    • Journal Title

      Therapeutic delivery

      Volume: 4 Issue: 3 Pages: 315-326

    • DOI

      10.4155/tde.12.164

    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Determination of the optimal cell-penetrating peptide sequence for intestinal insulin delivery based on molecular orbital analysis with self-organization maps2013

    • Author(s)
      Kamei N, Kikuchi S, Takeda-Morishita M, Terasawa Y, Yasuda A, Yamamoto S, Ida N, Nishio R, Takayama K
    • Journal Title

      J. Pharm. Sci.

      Volume: 102 Issue: 2 Pages: 469-479

    • DOI

      10.1002/jps.23364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] One-month subchronic toxicity study of cell-penetrating peptides for insulin nasal delivery in rats2013

    • Author(s)
      Khafagy El-S, Kamei N, Nielsen EJB, Nishio R, Takeda-Morishita M
    • Journal Title

      Eur. J. Pharm. Biopharm.

      Volume: 85 Issue: 3 Pages: 736-743

    • DOI

      10.1016/j.ejpb.2013.09.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Determination of the Optimal Cell-Penetrating Peptide Sequence for Intestinal Insulin Delivery Based on Molecular Orbital Analysis with Self-Organizing Maps2013

    • Author(s)
      N. Kamei, S. Kikuchi, M. Takeda-Morishita, Y. Terasawa, Yasuda, S. Yamamoto, N. Ida, R. Nishio, K. Takayama
    • Journal Title

      J. Pharm. Sci

      Volume: 102 Pages: 469-479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Mechanistic study of the uptake/permeation of cell-penetrating peptides across a Caco-2 monolayer and their stimulatory effect on epithelial insulin transport2013

    • Author(s)
      Kamei N, Onuki Y, Takayama K, Takeda-Morishita M
    • Journal Title

      J. Pharm. Sci.

      Volume: 102 Issue: 11 Pages: 3998-4008

    • DOI

      10.1002/jps.23708

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Mechanistic study on the uptake/permeation of cell-penetrating peptides across Caco-2 monolayer and their stimulatory effect on epithelial insulin transport2013

    • Author(s)
      N. Kamei, Y. Onuki, K. Takayama, M. Takeda-Morishita
    • Journal Title

      J Pharm Sci

      Volume: 102 Pages: 3998-4008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Cell-penetrating Peptide-Biodrug Strategy for Oral and Nasal Delivery: Review of Recent Findings2012

    • Author(s)
      El-S. Khafagy, N. Kamei and M. Takeda-Morishita
    • Journal Title

      J. Exp. Clin. Med.

      Volume: 4 Issue: 4 Pages: 198-202

    • DOI

      10.1016/j.jecm.2012.06.013

    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Oral biodrug delivery using cell-penetrating peptide2012

    • Author(s)
      El-S. Khafagy and M. Takeda-Morishita
    • Journal Title

      Adv Drug Deliv Rev

      Volume: 64 Issue: 6 Pages: 531-539

    • DOI

      10.1016/j.addr.2011.12.014

    • Data Source
      KAKENHI-PROJECT-23590056
  • [Journal Article] Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography2010

    • Author(s)
      N.Kamei, M.Morishita, Y.Kanayama, K.Hasegawa, M.Nishimura, E.Hayashinaka, Y.Wada, Y.Watanabe, K.Takayama
    • Journal Title

      J.Control.Release

      Volume: 146 Pages: 16-22

    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography2010

    • Author(s)
      N.Kamei, M.Morishita, 他
    • Journal Title

      J.Control.Release 146巻

      Pages: 16-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] The role of intermolecular interactions with penetratin and its analogue on the enhancement of absorption of nasal therapeutic peptides2010

    • Author(s)
      E.S.Khafagy, M.Morishita, K.Takayama
    • Journal Title

      Int.J.Pharm. 388巻

      Pages: 209-212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Structural requirements of penetratin absorption enhancement efficiency for insulin delivery2010

    • Author(s)
      E.S.Khafagy, M.Morishita, K.Takayama
    • Journal Title

      J.Control.Release

      Volume: 143 Pages: 302-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Structural requirements of penetratin absorption enhancement efficiency for insulin delivery2010

    • Author(s)
      E.S.Khafagy, M.Morishita, K.Takayama
    • Journal Title

      J.Control.Release 143巻

      Pages: 302-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] The role of intermolecular interactions with penetratin and its analogue on the enhancement of absorption of nasal therapeutic peptides2010

    • Author(s)
      E.S.Khafagy, M.Morishita, K.Takayama
    • Journal Title

      Int.J.Pharm.

      Volume: 388 Pages: 209-212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Efficiency of cell-penetrating peptides on the absorption of therapeutic peptides, proteins and hydrophilic macromolecules2009

    • Author(s)
      E.S.Khafagy, M.Morishita, K.Takayama
    • Journal Title

      Int.J.Pharm. 381巻

      Pages: 49-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Characterization of the inhibition of breast cancer resistance protein-mediated efflux of mitoxantrone by pharmaceutical excipients2009

    • Author(s)
      T.Yamagata, M.Morishita, H.Kusuhara, H.Benauer, Y.Sugiyama
    • Journal Title

      Int.J.Pharm. 370

      Pages: 216-219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Prediction of permeability of FD-4 through porous poly (2-hydroxyethyl methacrylate) membrane by multiple linear regression and artificial neural network2009

    • Author(s)
      F.Yanagawa, Y.Onuki, M.Morishita, K.Takayama
    • Journal Title

      Pharmazie 64

      Pages: 311-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Effect of cell-penetrating peptides on the nasal absorption of insulin2009

    • Author(s)
      E.S.Khafagy, M.Morishita, 他
    • Journal Title

      J.Control.Release 133巻

      Pages: 103-108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Efficiency of cell-penetrating peptides on the absorption of therapeutic peptides, proteins and hydrophilic macromolecules2009

    • Author(s)
      E.S.Khafagy, M.Morishita, K.Takayama
    • Journal Title

      Int.J.Pharm. 381

      Pages: 49-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Importance of intermolecular interaction on the improvement of intestinal therapeutic peptide/protein absorption using cell-penetrating peptides,2009

    • Author(s)
      N.Kamei, M.Morishita, K.Takayama
    • Journal Title

      J.Control.Release 136巻

      Pages: 179-186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Complexation hydrogels for oral delivery of insulin, interferon β and calcitonin2009

    • Author(s)
      N.Kamei, M.Morishita, 他
    • Journal Title

      J.Control.Release 134巻

      Pages: 98-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Importance of intermolecular interaction on the improvement of intestinal therapeutic peptide/protein absorption using cell-penetrating peptides2009

    • Author(s)
      N.Kamei, M.Morishita, K.Takayama
    • Journal Title

      J.Control. Release 136

      Pages: 179-186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Complexation hydrogels for oral delivery of insulin, interferon βand calcitonin2009

    • Author(s)
      N.Kamei, M.Morishita, H.Chiba, N.J.Kaviandan, N.A.Peppas, K.Takayama
    • Journal Title

      J.Control. Release 134

      Pages: 98-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Effect of cell-penetrating peptides on the nasal absorption of insulin2009

    • Author(s)
      E.S.Khafagy, M.Morishita, K.Isowa, J.Imai, K.Takayama
    • Journal Title

      J.Control. Release 133

      Pages: 103-108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Usefulness of cell-penetrating peptides to improve intestinal insulin absorption2008

    • Author(s)
      N.Kamei, M.Morishita, 他
    • Journal Title

      J.Control.Release 132巻

      Pages: 21-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Key functions in polymer carriers for intestinal absorption of insulin2008

    • Author(s)
      K.Nakamura, M.Morishita, 他
    • Journal Title

      Int.J.Pharm. 354巻

      Pages: 135-142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion2008

    • Author(s)
      Morishita M, et al
    • Journal Title

      J Control Release 132

      Pages: 99-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Complexation Hydrogels for Oral Insulin Delivery : Effects of Polymer Dosing on In Vivo Efficacy2008

    • Author(s)
      A.Tuesca, K.Nakamura, M.Morishita, 他
    • Journal Title

      J.Pharm.Sci. 97巻

      Pages: 2607-2618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] Permeation characteristics of oligoarginine through intestinal epithelium and its usefulness for intestinal peptide drug delivery2008

    • Author(s)
      N.Kamei, M.Morishita, J.Ehara, K.Takayama
    • Journal Title

      J.Control.Release 131巻

      Pages: 94-99

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Journal Article] A novel approach using functional peptides for efficient intestinal absorption of insulin2007

    • Author(s)
      M. Morishita, et. al.
    • Journal Title

      J Control Release 118

      Pages: 177-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] A novel approach using functional peptides for efficent intestinal absorption of insulin2007

    • Author(s)
      M.Morishita, 他
    • Journal Title

      J Control Release 118

      Pages: 177-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] A novel approach using functional petides for efficient instestinal absorption of insulin2007

    • Author(s)
      M.Morishita, 他
    • Journal Title

      J Control Release 118

      Pages: 177-184

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Involvement of fractal geometry on solute permeation through porous poly(2-hydoroxyethy1 methacrylate) membranes2006

    • Author(s)
      F.Yamagata, Y.Onuki, M.Morishita, K.Takayama
    • Journal Title

      J.Controlled Rel. 110

      Pages: 395-399

    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Novel oral insulin delivery systems based on complexation polymer hydrogels : Single and multiple administration studies in type 1 and 2 diabetic rats2006

    • Author(s)
      M.Morishita, T.Goto, et al.
    • Journal Title

      J.Controlled Rel. 110

      Pages: 587-594

    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Oral insulin delivery systems based on complexation polymer hydrogels2006

    • Author(s)
      M.Morishita, 他
    • Journal Title

      J Drug Delivery Sci Tech 16

      Pages: 19-24

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Docosahexaenoic acid and eicosapentaenoic acid induce changes in the physical properties of a lipid bilayer model membrane2006

    • Author(s)
      Y.Onuki, M.Morishita, Y.Chiba, S.Tokiwa, K.Takayama
    • Journal Title

      Chem.Pharm.Bull. 54

      Pages: 68-71

    • NAID

      110004820326

    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Novel oral insulin delivery system based on complexation polymer hydrogels:Single and multiple adminstration studies in type 1 and 2 diabetic rats2006

    • Author(s)
      M.Morishita, 他
    • Journal Title

      J Control Release 110

      Pages: 587-594

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Sendai virus-based insulin mucosal delivery system2006

    • Author(s)
      T.Goto, M.Morishita, et al.
    • Journal Title

      Pharm.Res. 23

      Pages: 384-391

    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Is the oral route possible for peptide and protein drug delivery2006

    • Author(s)
      M.Morishita and N.A.Peppas
    • Journal Title

      Drug Discovery Today 11

      Pages: 905-910

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Gastrointestinal transit and mucoadhesive characteristics of complexation hydrogels in rats2006

    • Author(s)
      T.Goto, M.Morishita, et al.
    • Journal Title

      J.Pharm.Sci. 95

      Pages: 462-469

    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Is the oral route possible for peptide and protein drug delivery?2006

    • Author(s)
      M. Morishita, N. A. Peppas
    • Journal Title

      Drug Discovery Today 11

      Pages: 905-910

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Oral insulin delivery systems based on complexation polymer hydrogels2006

    • Author(s)
      M.Morishita, T.Goto, et al.
    • Journal Title

      J.Drug Delivery Sci.Tech. 16

      Pages: 19-24

    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Characterization of insulin protection properities of complexation hydrogels in gastric and intestinal enzyme fluids2006

    • Author(s)
      T.yamagata, M.Morishita, et al.
    • Journal Title

      J.Controlled Rel. 112

      Pages: 343-349

    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Novel oral insulin delivery system based on complexation polymer hydrogels : Single and multiple adminstration studies in type 1 and 2 diabetic rats2006

    • Author(s)
      M. Morishita, et. al.
    • Journal Title

      J Control Release 110

      Pages: 587-594

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Is the oral route possible for peptide and protein drug delivery?2006

    • Author(s)
      M.Morishita, N.A.Peppas
    • Journal Title

      Drug Discovery Today 11

      Pages: 905-910

    • Data Source
      KAKENHI-PROJECT-17590044
  • [Journal Article] Oral insulin delivery systems based on complexation polymer hydrogels2006

    • Author(s)
      M. Morishita, et. al.
    • Journal Title

      J Drug Delivery Sci Tech 16

      Pages: 19-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Patent] 抗がん剤を含む難吸収性薬物の消化管吸収促進剤2017

    • Inventor(s)
      武田真莉子、亀井敬泰
    • Industrial Property Rights Holder
      学校法人神戸学院
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-02-10
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Patent] インスリンを含むバイオ薬物の消化管吸収促進剤2016

    • Inventor(s)
      武田真莉子、亀井敬泰
    • Industrial Property Rights Holder
      学校法人神戸学院
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-04-16
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Patent] L体pVECとリンスリンを含む経口または経腸投与医薬組成物2012

    • Inventor(s)
      森下真莉子他
    • Industrial Property Rights Holder
      森下真莉子他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-09-07
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Patent] 経鼻投与用医薬組成物2012

    • Inventor(s)
      森下真莉子,高山幸三,井田伸夫,青 木孝夫
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2012-10-29
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Patent] 両親媒性ペプチド含有医薬組成物2012

    • Inventor(s)
      森下真莉子,高山幸三,西尾玲士,井 田伸夫
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2012-09-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Patent] 経鼻投与用医薬組成物2012

    • Inventor(s)
      森下真莉子,高山幸三,井田伸夫,青 木孝夫
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2012-08-31
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Patent] 等電点が55以下の生理活性タンパク質+プロタミンあるいはその部分ペプチドを含有する腸管吸収性医薬組成物2012

    • Inventor(s)
      森下真莉子他
    • Industrial Property Rights Holder
      森下真莉子他
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-10-12
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Patent] 医薬組成物2012

    • Inventor(s)
      森下真莉子,高山幸三,井田伸夫,青 木孝夫
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2012-10-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Patent] 経鼻投与用医薬組成物2012

    • Inventor(s)
      森下真莉子,高山幸三,井田伸夫,青 木孝夫
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2012-07-05
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Patent] 経鼻投与用医薬組成物2011

    • Inventor(s)
      森下真莉子,高山幸三,井田伸夫,青 木孝夫
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Rights Type
      特許
    • Acquisition Date
      2011-04-23
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Patent] 細胞膜透過性ペプチド2009

    • Inventor(s)
      森下真莉子, 他
    • Industrial Property Rights Holder
      東レ
    • Filing Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Patent] 細胞膜透過性ペプチド2009

    • Inventor(s)
      森下真莉子, 他
    • Industrial Property Rights Holder
      東レ株式会社
    • Filing Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Patent] 経鼻投与用医薬組成物2008

    • Inventor(s)
      森下真莉子, 他
    • Industrial Property Rights Holder
      東レ株式会社
    • Filing Date
      2008-02-28
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Patent] 経鼻投与用医薬組成物2008

    • Inventor(s)
      森下真莉子, 他
    • Industrial Property Rights Holder
      東レ株式会社
    • Filing Date
      2008-02-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Patent] 経鼻投与用医薬組成物2008

    • Inventor(s)
      森下真莉子, 他
    • Industrial Property Rights Holder
      東レ株式会社
    • Filing Date
      2008-02-28
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Patent] 経鼻投与用医薬組成物2008

    • Inventor(s)
      森下真莉子, 他
    • Industrial Property Rights Holder
      東レ株式会社
    • Filing Date
      2008-02-28
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Patent] カチオン性ペプチドによる生理活性物質の腸管吸収促進2006

    • Inventor(s)
      森下真莉子他
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Number
      2006-034041
    • Filing Date
      2006-02-10
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Patent] 両親媒性ペプチド含有医薬組成物2006

    • Inventor(s)
      森下 真莉子, 他
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Number
      2006-178118
    • Acquisition Date
      2006-06-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Patent] カチオン性ペプチドによる生理活性物質の腸管吸収促進2006

    • Inventor(s)
      森下 真莉子, 他
    • Industrial Property Rights Holder
      東レ株式会社
    • Industrial Property Number
      2006-034041
    • Filing Date
      2006-02-10
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] ファインバブルの創薬・創剤における利活用の可能性 および経口・経皮適用時の生体への安全性評価2023

    • Author(s)
      武田 真莉子
    • Organizer
      ファインバブルの経口安全性セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K18566
  • [Presentation] ウルトラファインバブル(UFB)の創薬・創剤における有用性2023

    • Author(s)
      武田 真莉子
    • Organizer
      日本薬剤学会第38年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K18566
  • [Presentation] 水素封入ナノ微細気泡(H2 NanoGAS)水の飲水による酸化ストレス軽減効果の評価2023

    • Author(s)
      森下理咲子
    • Organizer
      第11回日本くすりと糖尿病学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K18566
  • [Presentation] 水素封入ウルトラファインバブル(H2NanoGAS)水によるエタノール誘導酸化ストレス軽減効果の評価2023

    • Author(s)
      森下理咲子
    • Organizer
      日本薬剤学会第38年会
    • Data Source
      KAKENHI-PROJECT-23K18566
  • [Presentation] ファインバブルの創薬・創剤における利活用の可能性 および経口・経皮適用時の生体への安全性評価2023

    • Author(s)
      武田 真莉子
    • Organizer
      第4回超音波分子診断治療研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K18566
  • [Presentation] 各種阻害剤およびsiRNAを用いたエンドサイトーシス評価系の再構築2022

    • Author(s)
      板垣 舞、杉山 千晶、西井 恵、亀井 優海、中瀬 生彦、武田 真莉子、亀井 敬泰
    • Organizer
      日本薬剤学会 第37年会
    • Data Source
      KAKENHI-PROJECT-20K07005
  • [Presentation] Penetratin併用経鼻投与によるインスリン脳送達後の脳内分布特性の評価2021

    • Author(s)
      横山夏季, 村田加帆, 山口舞佳, 田中恵里奈, 橋本彩花, 亀井敬泰, 武田真莉子
    • Organizer
      第37回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] 難吸収性中分子医薬の消化管吸収改善とin vitroからの予測性2021

    • Author(s)
      武田真莉子、亀井敬泰
    • Organizer
      日本薬剤学会
    • Data Source
      KAKENHI-PROJECT-20K07005
  • [Presentation] アルツハイマー病治療効果を高める抗アミロイドβ抗体薬の投与経路の比較評価:APPノックインマウスを用いた検討2020

    • Author(s)
      橋本彩花, 田中恵里奈, 村田加帆, 山口舞佳, 横山夏季, 坂東秀美, 亀井敬泰, 斉藤貴志, 西道隆臣, 武田真莉子
    • Organizer
      第36回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] Effective nose-to-brain delivery of exendin-4 via coadministration with cell-penetrating peptides for improving progressive cognitive dysfunction2020

    • Author(s)
      Kamei N, Okada N, Ikeda T, Choi H, Fujiwara Y, Okumura H, Takeda-Morishita M
    • Organizer
      The 10th Takeda Science Foundation Symposium on PharmaSciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] 細胞膜透過ペプチド併用投与を介したペプチド薬物の鼻腔―脳移行促進機構の解明2020

    • Author(s)
      坂東秀美, 松本淳志, 諏訪部晋, 有銘兼史, 亀井敬泰, 金沢貴憲, 武田真莉子
    • Organizer
      第36回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] Penetratin併用経鼻投与を介したExendin-4脳移行促進経路の評価2020

    • Author(s)
      坂東秀美, 松本淳志, 諏訪部晋, 有銘兼史, 亀井敬泰, 金沢貴憲, 武田真莉子
    • Organizer
      日本薬剤学会第35年会
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] Penetratin併用経鼻投与を介したExendin-4脳移行促進経路の評価2019

    • Author(s)
      坂東秀美, 諏訪部晋, 有銘兼史, 亀井敬泰, 金沢貴憲, 武田真莉子
    • Organizer
      第69回日本薬学会関西支部大会(誌上開催)
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] バイオ医薬の経口製剤化・脳標的化にチャレンジするDDS研究最前線2019

    • Author(s)
      武田真莉子
    • Organizer
      神戸ポートアイランド創薬フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] Improvement of Progressive Cognitive Dysfunction in the Senescence-Accelerated Mouse via Intranasal Administration of Exendin-4 with Cell-Penetrating Peptides2019

    • Author(s)
      Kamei N, Okada N, Ikeda T, Fujiwara Y, Okumura H, Takeda-Morishita M
    • Organizer
      The 46th Annual Meeting and Exposition, the Controlled Release Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] Penetratin併用による鼻腔―脳直接輸送経路を介したExendin-4の脳移行促進作用の検証2019

    • Author(s)
      諏訪部晋, 有銘兼史, 亀井敬泰, 武田真莉子
    • Organizer
      日本薬剤学会第34年会
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] 膜透過促進戦略に基づくバイオ薬物の経口吸収改善2019

    • Author(s)
      亀井敬泰, 武田真莉子
    • Organizer
      日本薬学会第139年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] Penetratin併用経鼻投与によるインスリン脳送達における三叉神経経路の寄与の評価2019

    • Author(s)
      有銘兼史, 諏訪部晋, 亀井敬泰, 金沢貴憲, 武田真莉子
    • Organizer
      日本薬剤学会第34年会
    • Data Source
      KAKENHI-PROJECT-19K07032
  • [Presentation] 難吸収性低分子薬物の膜透過性改善における細胞膜透過ペプチド併用戦略の有用性評価2018

    • Author(s)
      金岡将平, 小出夢子, 亀井敬泰, 武田真莉子
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] レプチンの全身吸収および脳移行性を高める細胞膜透過ペプチド併用経鼻投与法の有用性評価2018

    • Author(s)
      藤原由衣, 奥村遥, 湯浅瑛代, 亀井敬泰, 武田真莉子
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 膜透過促進機能を搭載したpH応答性ハイドロゲルによるインスリン経口送達システムの開発2018

    • Author(s)
      東山和広, 山本万由, 亀井敬泰, Peppas NA, 武田真莉子
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 糖尿病治療薬開発を推進するDDSの最新の話題2018

    • Author(s)
      武田真莉子
    • Organizer
      第79回大阪薬科大学公開教育講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 細胞膜透過ペプチド併用経鼻投与によるレプチンの全身および脳送達と肥満治療効果2018

    • Author(s)
      加藤雅大, 有銘兼史, 野々村杏奈, 藤原由衣, 湯浅瑛代, 荻野秀侑, 平野聖怜奈, Khafagy El-S, 亀井敬泰, 武田真莉子
    • Organizer
      第24回創剤フォーラム若手研究会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] レプチンおよび細胞膜透過ペプチドの繰り返し経鼻投与による肥満抑制効果の検証2018

    • Author(s)
      加藤雅大, 有銘兼史, 野々村杏奈, 荻野秀侑, 平野聖怜奈, 藤原由衣, 湯浅瑛代, Khafagy El-S, 亀井敬泰, 武田真莉子
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 難吸収性薬物の経口bioavailabilityを 改善するDDS研究最前線2018

    • Author(s)
      武田真莉子
    • Organizer
      - 新適塾 -「未来創薬への誘い」第41回会合
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] Potential of hydrophobic amino acid tryptophan as an absorption enhancer for the oral delivery of biopharmaceutics2018

    • Author(s)
      Kamei N, Tamiwa H, Miyata M, Takeda-Morishita M
    • Organizer
      The 45th Annual Meeting and Exposition, the Controlled Release Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] バイオ医薬の動態を制御するキー分子“細胞膜透過ペプチド”のDDSフロンティア研究2018

    • Author(s)
      武田真莉子
    • Organizer
      薬物動態懇話会4月例会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] Drug delivery and pharmaceutical technology: Recent advances in DDS research on the key molecule "cell- penetrating peptides" that controls the kinetics of the next- generation drug "biopharmaceuticals"2018

    • Author(s)
      Takeda-Morishita M, Kamei N
    • Organizer
      International Conference on Applied Pharmaceutical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] トリプトファン併用投与によるバイオ薬物の消化管粘膜吸収促進作用の評価2018

    • Author(s)
      亀井敬泰、宮田真里、武田真莉子
    • Organizer
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] トリプトファン併用投与によるバイオ薬物の消化管吸収改善効果の評価2018

    • Author(s)
      春名裕太, 宮田真里, 松村康耀, 民輪英之, 亀井敬泰, 武田真莉子
    • Organizer
      第24回創剤フォーラム若手研究会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] Recent advances in DDS research on the key molecule "cell-penetrating peptudes" that controls the kinetics of the next-generation drug "biopharmaceuticals".2017

    • Author(s)
      Takeda-Morishita M, Kamei N,
    • Organizer
      Pharmaceutical Sciences Seminar, Mahidon Univ., Thailand
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 疎水性アミノ酸併用によるインスリン経口吸収性の改善2017

    • Author(s)
      宮田真里、民輪英之、東山和広、平野聖怜奈、荻野秀侑、亀井敬泰、武田真莉子
    • Organizer
      第6回日本くすりと糖尿病学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 細胞膜透過ペプチドの生体膜透過ブースティング効果を基盤とするバイオ医薬の経粘膜デリバリーシステムの開発2017

    • Author(s)
      武田真莉子
    • Organizer
      日本薬学会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] インスリン経口製剤化 ~臨床開発動向と基礎研究の進展~2017

    • Author(s)
      武田真莉子
    • Organizer
      第27回 DM Club Meeting
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 細胞膜透過ペプチドを利用した難吸収性薬物の経口吸収促進基盤技術の確立2017

    • Author(s)
      亀井敬泰、武田真莉子
    • Organizer
      日本薬学会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 細胞膜透過ペプチド併用による難吸収性薬物の消化管粘膜透過性の改善2017

    • Author(s)
      金岡将平、小出夢子、亀井敬泰、武田真莉子
    • Organizer
      日本薬学会近畿支部大会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 疎水性アミノ酸併用によるペプチド薬物の経口吸収性の改善2017

    • Author(s)
      民輪英之、宮田真里、東山和広、荻野秀侑、平野聖怜奈、亀井敬泰、武田真莉子
    • Organizer
      日本薬剤学会第32年会
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 塩基性アミノ酸によるインスリンの消化管粘膜透過促進作用の評価2016

    • Author(s)
      今西 晴紀、牛尾 吏佐、広瀬 淳、Khafagy El-Sayed、亀井 敬泰、武田 真莉子
    • Organizer
      第5回日本くすりと糖尿病学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2016-10-29
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 非侵襲的投与ルートを介するインターフェロンβ送達法の開発2016

    • Author(s)
      小倉未咲, 民輪英之, 亀井敬泰, 武田真莉子
    • Organizer
      第66回日本薬学会近畿支部総会
    • Place of Presentation
      神戸
    • Year and Date
      2016-10-15
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] Usefulness of Cell-Penetrating Peptides in Noninvasive Nasal Delivery of PEGylated Interferon Beta2016

    • Author(s)
      N. Kamei, Y. Iwase, El-S. Khafagy, M. MIyamoto and M. Takeda-Morishita
    • Organizer
      43rd Annual Meeting of the Controlled Release Society
    • Place of Presentation
      Seattle, Washington, USA
    • Year and Date
      2016-07-17
    • Data Source
      KAKENHI-PROJECT-16K08211
  • [Presentation] 経鼻投与を介したペプチド薬物脳送達におけるcell-penetrating peptidesの有効性評価2014

    • Author(s)
      亀井敬泰,崔ハヨン,糸数玲,武田真莉子
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオ医薬の経口デリバリーシステムの開発研究2013

    • Author(s)
      武田(森下)真莉子
    • Organizer
      ドラッグデリバリーシステムと医薬品包装技術に関する国際会議,ファームテックジャパン2013
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 高度不飽和脂肪酸のGLP-1分泌促進作用を介した新規糖尿病治療法の開発2013

    • Author(s)
      亀井敬泰,志田貴之,田中智大,高山幸三,武田真莉子
    • Organizer
      第2回日本くすりと糖尿病学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-penetrating peptides in oral delivery systems for insulin2013

    • Author(s)
      Nielsen EJB, Yoshida S, Kamei N, Rahbek UR, Pedersen BR, Takayama K, Takeda-Morishtia M.
    • Organizer
      The 40th Annual Meeting and Exposition, the Controlled Release Society
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] シンポジウム趣旨説明,脳をターゲットとする薬物デリバリー研究の最前線2013

    • Author(s)
      武田(森下)真莉子
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 細胞膜透過ペプチドを利用した鼻から脳への効率的バイオ薬物デリバリー2013

    • Author(s)
      亀井敬泰,芝ひかり,武田(森下)真莉子
    • Organizer
      第29回日本DDS学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Long-term effectiveness and systemic/local safety of novel penetratin analogue for nasal insulin delivery2013

    • Author(s)
      Kamei N, Khafagy El-S, Hamamoto Y, Shiba H, Iwamae R, Kaiguchi M, Tanaka F, Matsumoto Y, Nielsen EJB, Nishio R, Takeda-Morishita M.
    • Organizer
      The 5th Asian Arden Conference
    • Place of Presentation
      Nagoya, Japan
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-Penetrating Peptides : Molecular function and usefulness as a novel oral bioavailability enhancer for therapeutic peptides and proteins2013

    • Author(s)
      Takeda M, Kamei N.
    • Organizer
      Post-Congress of 4th World Congress of Asian Psychiatry 2013
    • Place of Presentation
      Khon Kaen, Thailand
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオ医薬の経粘膜デリバリーシステムの開発研究2013

    • Author(s)
      武田(森下)真莉子,亀井敬泰
    • Organizer
      第29回日本DDS学会学術集会ワークショップ
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 鼻腔をを介した脳内バイオ薬物デリバリーにおける細胞膜透過ペプチドの有用性2013

    • Author(s)
      亀井敬泰,芝ひかり,武田(森下)真莉子
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Usefulness of cell-penetrating peptides for development of oral insulin delivery systems2013

    • Author(s)
      Nielsen EJB, Kamei N, Yoshida S, Takayama K, Takeda-Morishita M.
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] One-month subchronic toxicity study of cell-penetrating peptides on insulin nasal delivery in rats2013

    • Author(s)
      Khafagy El-S, Kamei N, Hamamoto Y, Shiba H, Iwamae R, Kaiguchi M, Tanaka F, Matsumoto Y, Nielsen EJB, Nishio R, Takeda-Morishita M.
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオ医薬の次世代型投与システムの研究開発動向と将来展望〜経口吸収FGの立場から〜2013

    • Author(s)
      武田真莉子
    • Organizer
      日本薬剤学会2025WGシンポジウム・バイオとナノが拓く医療イノベーション
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 膜透過性ペプチドをキャリアとするインスリン経口デリバリーシステムの開発2013

    • Author(s)
      岩前瑠衣紗,吉田真也, Nielsen EJB,亀井敬泰,高山幸三,武田(森下)真莉子
    • Organizer
      第63回日本薬学会近畿支部大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 経鼻投与に基づく脳内バイオ薬物デリバリー法の開発2013

    • Author(s)
      ひかり,亀井敬泰,武田(森下)真莉子
    • Organizer
      第63回日本薬学会近畿支部大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] キトサン誘導体添加によるインスリンの膜透過性及び安定性の向上2013

    • Author(s)
      大門裕貴,川上亘作,井澤浩則,亀井敬泰,武田(森下)真莉子,酒井秀樹,阿部正彦, Hill JP,有賀克彦
    • Organizer
      材料技術研究協会討論会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-penetrating peptideを用いたインスリンの粘膜吸収増進と安全性評価2013

    • Author(s)
      武田真莉子,亀井敬泰, Nielsen EJB, Khafagy El-S
    • Organizer
      第2回日本くすりと糖尿病学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオエンハンサー:細胞膜透過ペプチドを利用したバイオ薬物経口デリバリーシステムの開発研究2012

    • Author(s)
      武田(森下)真莉子
    • Organizer
      クラスター交流会
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-penetrating peptides : Molecular function and usefulness in the pharmaceutical development as a novel bioenhancer2012

    • Author(s)
      Takeda-Morishita M, Kamei N.
    • Organizer
      2012 International Advanced Drug Delivery Symposium
    • Place of Presentation
      Hsinchu, Taiwan
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-penetrating peptides: Molecular function and usefulness in the pharmaceutical development as a novel bioenhancer2012

    • Author(s)
      Takeda-Morishita M, Kamei N
    • Organizer
      2012 International Advanced Drug Delivery Symposium
    • Place of Presentation
      Hsinchu, Taiwan
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオ医薬品の非注射製剤の現状と開発動向2012

    • Author(s)
      武田(森下)真莉子
    • Organizer
      日本薬剤学会第27年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 細胞膜透過ペプチドを利用した経口インスリン送達システムの開発2012

    • Author(s)
      吉田真也,森下真莉子,佐藤智美,高山幸三
    • Organizer
      日本薬剤学会第27年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 細胞膜透過ペプチド(CPPs)を利用した脳への薬物送達システムの開発研究2012

    • Author(s)
      佐藤智美,森下真莉子,吉田真也,高山幸三
    • Organizer
      日本薬剤学会第27年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオエンハンサー:細胞膜透過ペプチドを利用したバイオ薬物経口デリバリーシステムの開発研究2012

    • Author(s)
      武田(森下)真莉子
    • Organizer
      クラスター
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-penetratingホームページ等peptidesを用いた生理活性ペプチドの粘膜吸収促進2011

    • Author(s)
      森下真莉子
    • Organizer
      第33回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Noninvasive peptide and protein delivery systems using cell-penetrating peptides2011

    • Author(s)
      Morishita M, Kamei N, Takayama K.
    • Organizer
      20^<th> Helsinki Drug Research Congress
    • Place of Presentation
      Helsinki, Finland
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 細胞膜透過性ペプチドによるバイオ薬物の消化管吸収促進2011

    • Author(s)
      森下真莉子
    • Organizer
      第29回物性物理化学研究会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] N Cell-penetrating peptides as a novel oral bioavailability enhancer for theraoeutic peptides and proteins : a mechanistic tudy of BA enhancement effects using Caco-2 cell monolayers2011

    • Author(s)
      Morishita M, Kamei N, Takayama K.
    • Organizer
      日本薬物動態学会第26年会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 基礎薬学における糖尿病薬の研究インスリン非注射製剤開発への試み2010

    • Author(s)
      森下真莉子
    • Organizer
      日本医療薬学会第20年会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 基礎薬学における糖尿病薬の研究-イソスリン非注射製剤開発への試み2010

    • Author(s)
      森下真莉子
    • Organizer
      日本医療薬学会第20年会
    • Place of Presentation
      千葉、日本
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 機能性ペプチドをキャリアとするバイオ薬物の経粘膜デリバリー2010

    • Author(s)
      森下真莉子
    • Organizer
      第12回ヒューマンサイエンス総合研究ワークショップ
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Oral Insulin Delivery Systems : Development of carrier systems and molecular imaging analysis of intestinal insulin absorption using PET2010

    • Author(s)
      M.Morishita
    • Organizer
      the 1st Novo Nordisk Oral Protein Delivery
    • Place of Presentation
      Denmark
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 細胞膜透過ペプチドによるインスリン細胞膜透過促進機構の解明2010

    • Author(s)
      山本修一、森下真莉子、高山幸三
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Noninvasive delivery systems for therapeutic peptides and proteins2010

    • Author(s)
      森下真莉子
    • Organizer
      Japan-Egypt workshop
    • Place of Presentation
      Japan
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 小腸粘膜免疫細胞ターゲティング型経口ワクチンの開発2010

    • Author(s)
      吉田美亜、森下真莉子、國澤純、高山幸三
    • Organizer
      第26回日本DDS学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Novel technology using cell-penetrating peptides for oral delivery of therapeutic peptides and proteins.2010

    • Author(s)
      森下真莉子
    • Organizer
      IPTS
    • Place of Presentation
      Antalya, Turkey
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Novel technology using cell-penetrating peptides for oral delivery of therapeutic peptides and proteins2010

    • Author(s)
      M.Morishita
    • Organizer
      IPTS 2010
    • Place of Presentation
      Antalya, Turkey
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] バイオ医薬の経粘膜送達法:非侵襲的バイオ医薬製剤の開発と治療の最前線2010

    • Author(s)
      森下真莉子
    • Organizer
      日本薬剤学会第25年会
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] In silico解析による新規Cell penetrating peptidesの開発2010

    • Author(s)
      寺澤義明、森下真莉子、井田伸夫、西尾玲士、安田昭仁、高山幸三
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 逆ミセル型高分子ナノ粒子を利用した新規DDSキャリアの開発2010

    • Author(s)
      武藤慧也、森下真莉子、井田伸夫、西尾玲士、安田昭仁、高山幸三
    • Organizer
      第26回日本DDS学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] BCRP(Breast Cancer Resistance Protein)基質:Sulfasalazineの消化管吸収特性2010

    • Author(s)
      森本望、森下真莉子、楠原洋之、藤田卓也、杉山雄一、高山幸三
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Oral Insulin Delivery Systems : Development of carrier systems and molecular imaging analysis of intestinal insulin absorption using PET.2010

    • Author(s)
      森下真莉子
    • Organizer
      the 1st Novo Nordisk Oral Protein Delivery
    • Place of Presentation
      Denmark
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] サキナビルに対するリトナビルの薬物動態学的ブースター効果の解析2010

    • Author(s)
      都丸充子、森下真莉子、高山幸三、前田和哉、杉山雄一
    • Organizer
      第18回肝病態生理研究会
    • Place of Presentation
      山形
    • Year and Date
      2010-05-26
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Structure-activity relationship of penetratin analogues for peptides delivery2009

    • Author(s)
      E.S.Khafagy, M.Morishita, 他
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] バイオ薬物の効率的消化管吸収を目指した新規細胞膜透過ペプチドの開発2009

    • Author(s)
      寺澤義明、森下真莉子、他
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] バイオ薬物の経口吸収促進ツールとなる細胞膜透過ペプチドのIn silico解析に基づく開発研究2009

    • Author(s)
      寺澤義明、森下真莉子、他
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 細胞膜透過ペプチドによるインスリン吸収促進作用のCaco-2単層膜における評価2009

    • Author(s)
      山本修一、森下真莉子、亀井敬泰、高山幸三
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 機能性ペプチドによるバイオ薬物の消化管吸収改善とそのメカニズムの検討2009

    • Author(s)
      亀井敬泰、森下真莉子、高山幸三
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Structural requirement of penetratin efficiency for insulin delivery2009

    • Author(s)
      E.S.Khafagy、M.Morishita、他
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Evaluation of pharmaceutical excipients as inhibitors of intestinal efflux transporters2009

    • Author(s)
      M.Morishita, T.Yamagata, H.Kusuhara, Y.Sugiyama, K.Takayama
    • Organizer
      BioMedical Transporters 2009
    • Place of Presentation
      Thun, Switzerland
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Efficiency of penetratin analogues on the nasal peptides delivery2009

    • Author(s)
      E.S.Khafagy, M.Morishita, 他
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] バイオ薬物の経口吸収促進ツールとなる細胞膜透過ペプチドのInsilico解析に基づく開発研究2009

    • Author(s)
      寺澤義明、森下真莉子、井田伸夫、西尾玲士、高山幸三
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] BCRP(Breast Cancer Resistance Protein)基質薬物の消化管吸収を改善する阻害剤の探索2009

    • Author(s)
      森本望、森下真莉子、楠原洋之、杉山雄一、高山幸三
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 消化管膜の多彩な機能を活かした創薬、創剤研究の最前線2009

    • Author(s)
      森下真莉子
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Use of Cell-Penetrating Peptides in Enhancing Mucosal Absorption of Therapeutic Peptides and Proteins2009

    • Author(s)
      森下真莉子
    • Organizer
      Asian Federation for Pharmaceutical Sciences
    • Place of Presentation
      Fukuoka, Japan
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 細胞膜透過ペプチドによるインスリンCaco-2単層膜透過促進機構の解明2009

    • Author(s)
      山本修一、森下真莉子、他
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] 細胞膜透過ペプチドの消化管バイオ薬物吸収促進機構における分子間相互作用の寄与2008

    • Author(s)
      亀井敬泰、森下真莉子、高山幸三
    • Organizer
      日本薬剤学会第23年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] バイオ医薬の経鼻吸収における細胞膜透過性ペプチドの有用性評価2008

    • Author(s)
      枝佳美、El-Sayed Kafagy、森下真莉子、高山幸三
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Effect of cell-penetrating peptides (CPPs) on the nasal absorption of insulin2008

    • Author(s)
      E.S.Khafagy, M.Morishita, K.Takayama
    • Organizer
      日本薬剤学会第23年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] デリバリーキャリアを利用した次世代型経口糖尿病治療システムの構築2008

    • Author(s)
      森下真莉子
    • Organizer
      第24回日本DDS学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] バイオ薬物の消化管吸収における細胞膜透過性ペプチドの有効性の評価2008

    • Author(s)
      池野洋平、森下真莉子、亀井敬泰、高山幸三
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Use of Pharmaceutical Excipients in Enhancing GI Absorption by Inhibiting Efflux Transporters2008

    • Author(s)
      Morishita M
    • Organizer
      2^<nd> Asian Paific Regional Meeting
    • Place of Presentation
      Shanghai, China
    • Data Source
      KAKENHI-PROJECT-20590042
  • [Presentation] Effect of excipients on the GI absorption of drugs : influence on dissolution or efflux transporters2007

    • Author(s)
      M. Morishita
    • Organizer
      6th Symposium New Developments in Clinical Pharmacy and Clinical Pharmacology
    • Place of Presentation
      Germany
    • Year and Date
      2007-06-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] 排出系トランスポーター阻害による薬物吸収促進2007

    • Author(s)
      森下 真莉子
    • Organizer
      日本薬学会第127年会
    • Place of Presentation
      富山
    • Year and Date
      2007-03-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel approach using functional peptides for efficient intesthlal absorption of peptide and protein drugs2007

    • Author(s)
      Morishita M
    • Organizer
      6th Retrometabolism based drug design and targeting conference
    • Place of Presentation
      Hungary
    • Year and Date
      2007-06-04
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel approach using functional peptides for efficient intestinal absorption of peptide and protein drugs2007

    • Author(s)
      M. Morishita
    • Organizer
      5th Retrometabolism based drug design and targeting conference
    • Place of Presentation
      Hungary
    • Year and Date
      2007-06-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] Effect of excipients on the GI absorption of drugs:influence on dissolution or efflux transporters2007

    • Author(s)
      M.Morishita
    • Organizer
      6th Symposium New Developments in Clinical Pharmacy and Clinical Pharmacology
    • Place of Presentation
      Germany
    • Year and Date
      2007-06-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] 日本薬剤学会へのフォーカスグループ制度の導入提案(4)2007

    • Author(s)
      森下 真莉子
    • Organizer
      日本薬剤学会第22年会
    • Place of Presentation
      大宮
    • Year and Date
      2007-05-21
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel approach using functional peptides for eifficient intestinal absorption of peptide and protein drugs2007

    • Author(s)
      Morishita M
    • Organizer
      6th Retrometabolism based drug design and targetilg conference
    • Place of Presentation
      Hungary
    • Year and Date
      2007-06-04
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel approach using functional peptides for efficient intestinal absorption of peptide and protein drugs2007

    • Author(s)
      M.Morishita
    • Organizer
      6th Retrometabolism based drug design and targeting conference
    • Place of Presentation
      Hungary
    • Year and Date
      2007-06-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel approach using functional peptides for efficient intestinal abs orption of biologicals2006

    • Author(s)
      M.Morishita
    • Organizer
      Membrane-permeable peptides:Chemistry, biology and therapeutic applications
    • Place of Presentation
      Japan
    • Year and Date
      2006-11-10
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel approach using functional peptides for efficiedt intestinal absorption of biologicals2006

    • Author(s)
      M. Morishita
    • Organizer
      Membrane-permeable peptides : Chemistry, biology and therapeutic applications
    • Place of Presentation
      Japan
    • Year and Date
      2006-11-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] 経口バイオアベイラビリティを改善する次世代ストラテジー:薬物物性を操作し、生体膜機能を利用する2006

    • Author(s)
      山下 伸二、森下 真莉子
    • Organizer
      日本薬学会第126年会
    • Place of Presentation
      仙台
    • Year and Date
      2006-03-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] 消化管トランスポーター機能制御に基づく経口薬物デリバリー2006

    • Author(s)
      森下 真莉子
    • Organizer
      第22回日本DPS学会
    • Place of Presentation
      東京
    • Year and Date
      2006-07-07
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] Improvement of oral insulin bioavailavility by cell-penetrating peptides2006

    • Author(s)
      M. Morishita, et. al.
    • Organizer
      AAPS annual meeting and exposition
    • Place of Presentation
      USA
    • Year and Date
      2006-10-30
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] Effect of excipients on the GI absorption of drugs2006

    • Author(s)
      M.Morishita
    • Organizer
      33rd Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Austria
    • Year and Date
      2006-07-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] Improvement of oral insulin bioavailability by cell-penetrating peptides2006

    • Author(s)
      M.Morishita, 他
    • Organizer
      The 2006 AAPS Annual Meeting and Exposition
    • Place of Presentation
      USA
    • Year and Date
      2006-10-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] 機能性ペプチドによるバイオ医薬の経口BA改善の実証2006

    • Author(s)
      森下 真莉子
    • Organizer
      日本薬学会第126年会
    • Place of Presentation
      仙台
    • Year and Date
      2006-03-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] Impact of pharmaceutical excipients on intestinal transporter function2005

    • Author(s)
      M.Morishita
    • Organizer
      27th Mini-Symposium of Dept of Molecular Pharmacokinetics, the University of Tokyo & APSTJ Global Education Seminar East 3-05
    • Place of Presentation
      東京
    • Year and Date
      2005-09-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] Formulation optimization for oral peptide and protein delivery2005

    • Author(s)
      M.Morishita
    • Organizer
      3rd World Conference on Drug Absorption, Transport and Delivery
    • Place of Presentation
      Spain
    • Year and Date
      2005-04-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A nover delivery system using memvrane-permeable peptides for efficient oral absorption of peptide and protein drugs2005

    • Author(s)
      M. Morishita, et. al.
    • Organizer
      The 2nd AASP Symposium
    • Place of Presentation
      Thailand
    • Year and Date
      2005-11-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] ペプチド・タンパク薬物の経口デリバリーにおける塩基性キャリアペプチド2005

    • Author(s)
      森下 真莉子, 他
    • Organizer
      第21回日本DDS学会
    • Place of Presentation
      長崎
    • Year and Date
      2005-07-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel approach using memvrane-permeavle oligoarginine peptide(Arg) 6 for efficient intestinal absorption of peptide and protein drugs2005

    • Author(s)
      M. Morishita, et. al.
    • Organizer
      AAPS annual meeting and exposition
    • Place of Presentation
      USA
    • Year and Date
      2005-11-06
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel delivery system using membrane-permeable peptides for efficient oral absorption of peptide and protein drugs2005

    • Author(s)
      M.Morishita, 他
    • Organizer
      The 2nd AASP Symposium
    • Place of Presentation
      Thailand
    • Year and Date
      2005-11-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] A novel approach using membrane-permeable oligoarginine peptide (Arg)6 for efficient intestinal absorption of peptide and protein drugs2005

    • Author(s)
      M.Morishita, 他
    • Organizer
      AAPS annual meeting and exposition
    • Place of Presentation
      USA
    • Year and Date
      2005-11-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] Novel carrier systems for oral peptide and protein delivery2005

    • Author(s)
      M.Morishita
    • Organizer
      5th Retrometabolism based drug design and targeting conference
    • Place of Presentation
      Japan
    • Year and Date
      2005-05-08
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590044
  • [Presentation] Noninvasive peptide and protein delivery systems using cell-penetrating peptides

    • Author(s)
      Mariko Morishita
    • Organizer
      HDR2011 congress(招待講演)
    • Place of Presentation
      ヘルシンキ
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] 細胞膜透過性ペプチドによるバイオ薬物の消化管吸収促進

    • Author(s)
      森下真莉子
    • Organizer
      第29回物性物理化学研究会(招待講演)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオ医薬の経口デリバリーシステムの開発研究

    • Author(s)
      武田(森下)真莉子
    • Organizer
      ファームテックジャパン2013
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-penetrating peptideを用いたインスリンの粘膜吸収増進と安全性評価

    • Author(s)
      武田真莉子, 亀井敬泰, Nielsen EJB, Khafagy El-S
    • Organizer
      第2回日本くすりと糖尿病学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオ医薬の経粘膜デリバリーシステムの開発研究

    • Author(s)
      武田(森下)真莉子, 亀井敬泰
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] バイオ医薬の次世代型投与システムの研究開発動向と将来展望

    • Author(s)
      武田真莉子
    • Organizer
      日本薬剤学会2025WGシンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-Penetrating Peptides: Molecular function and usefulness as a novel oral bioavailability enhancer for therapeutic peptides and proteins

    • Author(s)
      Takeda M, Kamei N
    • Organizer
      Post-Congress of 4th World Congress of Asian Psychiatry 2013
    • Place of Presentation
      Khon Kaen, Thailand
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-penetrating peptides as a novel oral bioavailability enhancer for therapeutic peptides and proteins:a mechanistic study of BA enhancement effects using Caco-2 cell monolayers

    • Author(s)
      Mariko Morishita
    • Organizer
      日本薬物動態学会第26年会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] Cell-penetrating peptides in oral delivery systems for insulin

    • Author(s)
      Nielsen EJB, Yoshida S, Kamei N, Rahbek UR, Pedersen BR, Takayama K, Takeda-Morishtia M
    • Organizer
      The 40th Annual Meeting and Exposition, the Controlled Release Society
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-23590056
  • [Presentation] cell penetrating peptideを用いた生理活性ペプチドの粘膜吸収増進

    • Author(s)
      森下真莉子
    • Organizer
      第33回生体膜と薬物の相互作用シンポジウム(招待講演)
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-23590056
  • 1.  Kamei Noriyasu (40637451)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 38 results
  • 2.  TAKAYAMA Kozo (00130758)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 41 results
  • 3.  森下 理咲子 (70899963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  Khafagy El-Sayed
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results

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