MATSUNAGA Takuya 松永卓也

Researcher Number	70260768
Other IDs
Affiliation (based on the past Project Information) *help	2011 – 2013: 香川大学, 医学部, 教授 2010: 宮崎大学, 医学部, 准教授 2007: Sapporo Medical University, 医科部, 講師 2001 – 2007: 札幌医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Hematology / Biological Sciences / Hematology Except Principal Investigator Hematology
Keywords	Principal Investigator 抗癌剤耐性 / Cord blood / CD34陽性細胞 / 臍帯血 / Artificial platelets / CD34^+ cells / 人工血小板 / Platelets / Red blood cells / CD 34+ cells … More / Artificial bone marrow / Immortalized stromal cells / 不死化ヒトストローマ細胞 / 血小板 / 赤血球 / 人工骨髄 / 不死化ヒト骨髄ストローマ細胞 / Telomerase / Hematopoietic stem cell transplantation / Immortalized gene / Bone marrow stromal cells / テロメラーゼ / 造血幹細胞移植 / 不死化遺伝子 / 骨髄ストローマ細胞 / 低酸素 / 白血病幹細胞 / HIF-1α / HIF-1alpha / 低酸素選択性薬剤 / 低酸素環境 / AML / 血液腫瘍学 / VLA-4阻害剤 / 急性骨髄性白血病 / 分子標的療法 / 急性骨随性白血病 / フィブロネクチン由来ペプチド / Beta-1インテグリン / 抗癌剤抵抗性 / 骨髄間質細胞 / 骨転移性癌 / 造血器悪性腫瘍 / 細胞接着 / ストローマ細胞 / 急性白血病 … More Except Principal Investigator テネシンーC / 輸血製剤 / 造血幹細胞 / ペプチド / テネシン－Ｃ / 輸血学 Less

HIF-1alpha阻害剤と抗癌剤を併用した新しい白血病幹細胞根絶療法の開発Principal Investigator
- Principal Investigator
  
  松永卓也
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kagawa University
Elucidation of chemoresistance in hypoxic condition and a developmentof radical treatment in AML cells by hypoxia specific inhibitory drugsPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Takuya
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kagawa University
  University of Miyazaki
Development of transfusion products derived from hematopoietic stem cells using TNIII14 peptide
- Principal Investigator
  
  KUBUKI Yohko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Miyazaki
急性骨髄性白血病の実践的治療モデルにおける抗癌剤/VLA-4阻害剤併用療法の検討Principal Investigator
- Principal Investigator
  
  松永卓也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Development of the system to produce large scale generation of human platelets from cord blood CD34^+ cells in vitroPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Takuya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
フィブロネクチン由来ペプチドを用いた急性骨髄性白血病の新しい分子標的療法の開発Principal Investigator
- Principal Investigator
  
  松永卓也
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
造血器悪性腫瘍および骨転移性癌の骨随間質細胞との相互作用からみた抗癌剤抵抗性Principal Investigator
- Principal Investigator
  
  松永卓也
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Development of the system to expand hematopoietic stem cells using gene modification techniquePrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Takuya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University
ストローマ細胞との接着による急性白血病細胞の抗癌剤耐性誘導機序の解明Principal Investigator
- Principal Investigator
  
  松永卓也
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Sapporo Medical University
Development of hematopoietic stem cell transplantation using in vitro expanded bone marrow stromal cellsPrincipal Investigator
- Principal Investigator
  
  MATSUNAGA Takuya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Sapporo Medical University

All 2012 2010 2008 2007 2006 2004 2003

All Journal Article Presentation

[Journal Article] Elevated HIF-1α expression of acute myelogenous leukemia stem cells in the endosteal hypoxic zone may be a cause of minimal residual disease in bone marrow after chemotherapy2012
- Author(s)
  松永卓也
- Journal Title
  
  Leukemia Research
  
  Volume: (印刷中) Issue: 6 Pages: 122-124
- DOI
  10.1016/j.leukres.2012.02.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J10490, KAKENHI-PROJECT-22591042, KAKENHI-PROJECT-23591397, KAKENHI-PROJECT-24890177
[Journal Article] Elevated HIF-1expression of acute myelogenous leukemia stem cells in the endosteal hypoxic zone may be a cause of minimal residual disease in bone marrow after chemotherapy2012
- Author(s)
  Matsunaga T, Imataki O, Torii E, Kameda T, Shide K, Shimoda H, Kamiunten A, Sekine M,Taniguchi Y, Yamamoto S, Hidaka T, KatayoseK, Kubuki Y, Dobashi H, Bandoh S, OhnishiH, Fukai F, Shimoda K
- Journal Title
  
  Leuk Res
  
  Volume: 36
- Data Source
  KAKENHI-PROJECT-22591042
[Journal Article] Potentiated activation of VLA-4 and VLA-5 accelerates proplatelet-like formation.2012
- Author(s)
  MatsunagaT, FukaiF, KamedaT, ShideK, ShimodaH, Torii E, KamiuntenA, SekineM, YamamotoS, HidakaT, KubukiY, YokokuraS, UemuraM, MatsuokaA, WakiF, MatsumotoK, KanajiN, IshiiT, ImatakiO, DobashiH, BandohS, ShimodaK
- Journal Title
  
  Ann Hematol
  
  Volume: 91 (10) Pages: 1633-1643
- Data Source
  KAKENHI-PROJECT-22591066
[Journal Article] Ex vivo large-scale generation of human red blood cells from cord blood CD34(+) cells by co-culturing with macrophages2008
- Author(s)
  Fujimi, A., Matsunaga, T
- Journal Title
  
  Int J Hematol (Epub ahead of print)
- NAID
  10025158459
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Resolution of liver cirrhosis using vitamin A coupled liposomes to deliver siRNA against a collaen-specific chaperone2008
- Author(s)
  Sato Y, Matsunaga T.
- Journal Title
  
  Nat Biotechnol 38
  
  Pages: 431-442
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] A Phase I trial of arterial infusion chemotherapy with gemcitabine and 5-fluorouracil for unresectable advanced pancreatic cancer after vascular supply distribution via super selective embolization.2008
- Author(s)
  Miyanishi, K., Matsunaga. T
- Journal Title
  
  Jpn J Clin Oncol. 38
  
  Pages: 268-274
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] A phase I trial of arterial infusion chemotherapy with gemcitabine and 5-fluorour acil for unresectable advanced pancreatic cancer after vascular supply distribution via super selecitive embolization2008
- Author(s)
  Miyanishi K, Matsunaga T.
- Journal Title
  
  Epn J Clin Oncol 38
  
  Pages: 268-274
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Aberrant crypt foci as precursors of the dysplasia-carcinoma sequence inpatients with ulcerative colitis2008
- Author(s)
  Kukitsu T, Matsunaga T.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 48-54
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Combination therapy of an anticancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion-mediated drug resistance of acute myelogenous leukemia2008
- Author(s)
  Matsunaga, T., Fukai, F.
- Journal Title
  
  Leukemia 22
  
  Pages: 353-360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Aberrant crypt foci as precursors of the dysplasia-carcinoma sequence in patients with ulcerative colitis2008
- Author(s)
  Kukitsu, T., Matsunaga, T
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 48-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Ex vivo large scale generation of human platelets from cord blood CD34^+ cells2008
- Author(s)
  Matsunaga T, et. al.
- Journal Title
  
  Leukemia 22
  
  Pages: 353-360
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Ex vivo large-scale generarion of human red blood cells from cord blood CD34^+ cells by co-culturing with macrophages2008
- Author(s)
  Fujimi A, Matsunaga T.
- Journal Title
  
  Int J Hematol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Resolution of liver cirrhosis using vitamin A coupled liposomes to deliver siRNA against a collagen-specific chaperone2008
- Author(s)
  Sato, Y., Matsunaga, T
- Journal Title
  
  Nat Biotechnol 26
  
  Pages: 431-442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Essential role of protein kinase C {zeta} in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP.2007
- Author(s)
  Kuribayashi, K., Matsunaga, T
- Journal Title
  
  J Cell Biol 176
  
  Pages: 1049-1060
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Phase I study of S-1, docetaxel and cisplatin combination chemotherapy in patients with unresectable metastatic gastric cancer2007
- Author(s)
  Takayama, T., Matsunaga, T
- Journal Title
  
  Br J Cancer 97
  
  Pages: 851-856
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Phase I study of S-1, docetaxel and cisplatin combination chemotherapy inpatients with unresectable metastatic gastric cancer2007
- Author(s)
  Takayama T, Matsunaga T.
- Journal Title
  
  Br J Cancer 97
  
  Pages: 851-856
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Combination therapy of an anti-cancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion mediated-drug resistance of acute myelogenous leukemia2007
- Author(s)
  Matsunaga T, et. al.
- Journal Title
  
  Leukemia
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015043
[Journal Article] Combination therapy of alland-cancer drug with the FNInl4 peptide of fibronectin effectively overwmes cell adhesion mediated-drug resistance of acute myelogenous leukemia2007
- Author(s)
  Matsunaga T, et. al.
- Journal Title
  
  Leukemia (Epub ahead of print)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Essential role of protein kinase C {zeta} in transducing a motility signal induced by superoxide and a chemotactic peptide, fMLP2007
- Author(s)
  Kuribayashi K, Matsunaga T.
- Journal Title
  
  J Cell Biol 176
  
  Pages: 1049-1060
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Combination therapy of an anti-cancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion mediated-drug resistance of acute myelogenous leukemia.2007
- Author(s)
  Matsunaga T, et. al.
- Journal Title
  
  Leukemia (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Hepatitis C virus core protein promotes proliferation of human hepatoma Huh-7 cells through enhancement of transforming growth factor-[alpha] expression via activation of NF-DB2006
- Author(s)
  Sato, Y., Matsunaga, T
- Journal Title
  
  Gut 55
  
  Pages: 1801-1808
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Ex vivo large scale generation of human platelets from cord blood CD34* cells2006
- Author(s)
  Matsunaga, T., Tanaka, I
- Journal Title
  
  Stem Cells 24
  
  Pages: 2877-2887
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Amelioration of murine dextran sulfate sodium-induced colitis by ex vivo extracellular superoxide dismutase gene transfer2006
- Author(s)
  Oku, T., Matsunaga, T
- Journal Title
  
  Inflamm Bowel Dis 12
  
  Pages: 630-640
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Hepatitis C virus core protein promotes proliferation of human hepatoma Huh-7 cells through enhancement of transforming growth factor-[alpha] expression via activation of NF-kB2006
- Author(s)
  Sato Y, Matsunaga T.
- Journal Title
  
  Gut 55
  
  Pages: 1801-1808
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Amelioration ofmurine dextran sulfate sodium-induced colitis by ex vivo extrace llular superoxide dismutase gene transfer2006
- Author(s)
  Oku T, Matsunaga T.
- Journal Title
  
  Inflamm Bowel Dis 12
  
  Pages: 630-640
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Ex vivo large-scale generation of human platelets from cord blood CD34^+ cells.2006
- Author(s)
  Matsunaga T, Iyama S, Sato T, et al.
- Journal Title
  
  Stem cells 24
  
  Pages: 2877-2887
- Data Source
  KAKENHI-PROJECT-18591076
[Journal Article] Recovery of neutrophil count by ganciclovir in patients with chronic idiopathic neutropenia associated with cytomegalovirus infection in bone marrow stromal cells2004
- Author(s)
  Hirayama Y, Matsunaga T et al.
- Journal Title
  
  Int J Hematol 79
  
  Pages: 337-339
- NAID
  10013082044
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-β2m-/- repopulating cells.2004
- Author(s)
  Kobune M, Matsunaga T et al.
- Journal Title
  
  Blood 104
  
  Pages: 1002-1009
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Chemoprevention of colorectal cancer.2004
- Author(s)
  Niitsu Y, Matsunaga T et al.
- Journal Title
  
  Cancer Chemother Pharmacol 54 Suppl 1
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-β32m-/- repopulating cells2004
- Author(s)
  Kobune M, Ito Y, Kawano Y, Sasaki K, Uchida H, Nakamura K, Dehari H, Chiba H, Takimoto R, Matsunaga T, Terui T, Kato J, Niitsu Y, Hamada H.
- Journal Title
  
  Blood 104
  
  Pages: 1002-1009
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Recovery of neutrophil count by ganciclovir in patients with chronic idiopathic, neutropenia associated with cytomegalovirus infection in bone marrow stromal cells2004
- Author(s)
  Hirayama Y, Sakamaki S, Tsuji Y, Chiba H, Matsunaga T, Takimoto R, Kato J, Niitsu Y.
- Journal Title
  
  Int J Hematol 79
  
  Pages: 337-339
- NAID
  10013082044
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Plasma GSTP1-1 as a prognostic factor in patients with advanced non-Hodgkin's lymphoma (stages III and IV)2004
- Author(s)
  Katahira T, Takayama T, Miyanishi K, Hayashi T, Ikeda T, Takahashi Y, Takimoto R, Matsunaga T, Kato J, Niitsu Y.
- Journal Title
  
  Clin Cancer Res 10
  
  Pages: 7934-7940
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Glutathione-S-transferase P1-1 protects aberrant crypt foci from apoptosis induced by deoxycholic acid2004
- Author(s)
  Nobuoka A, Takayama T, Miyanishi K, Sato T, Takanashi K, Hayashi T, Kukitsu T, Sato Y, Takahashi M, Okamoto T, Matsunaga T, Kato J, Oda M, Azuma T, Niitsu Y.
- Journal Title
  
  Gastroenterology 127
  
  Pages: 428-443
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Decrease of Smad4 gene expression in patients with essential thrombocythaemia may cause an escape from suppression of megakaryopoiesis by transforming growth factor-b1 (TGF-b1).2004
- Author(s)
  Kuroda H, Matsunaga T et al.
- Journal Title
  
  Br J Haematol 124
  
  Pages: 211-220
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in jurkat cells2004
- Author(s)
  Sato T, Machida, T, Takahashi S, Iyama S, Sato Y, Kuribayashi K, Takada K, Oku T, Kawano Y, Okamoto T, Takimoto R, Matsunaga T, Takayama T, Takahashi M, Kato J, Niitsu Y.
- Journal Title
  
  J Immunol 173
  
  Pages: 285-296
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Glutathione-S-transferase P1-1 protects aberrant crypt foci from apoptosis induced by deoxycholic acid.2004
- Author(s)
  Nobuoka A, Matsunaga T et al.
- Journal Title
  
  Gastroenterology 127
  
  Pages: 428-443
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Decrease of Smad4 gene expression in patients with essential thrombocythaemia may cause an escape from suppression of megakaryopoiesis by transforming growth factor-(31 (TGF-β1)2004
- Author(s)
  Kuroda H, Matsunaga T, Terui T, Tanaka I, Takimoto R, Fujikawa K, Takayama T, Kato J, Hirayama Y, Sakamaki S, Kohda K, Niitsu Y.
- Journal Title
  
  Br J Haematol 124
  
  Pages: 211-220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Plasma GSTP1-1 as a prognostic factor in patients with advanced non-Hodgkin's lymphoma (stages III and IV).2004
- Author(s)
  Katahira T, Matsunaga T et al.
- Journal Title
  
  Clin Cancer Res 10
  
  Pages: 7934-7940
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Chemoprevention of colorectal cancer2004
- Author(s)
  Niitsu Y, Takayama T, Miyanishi K, Nobuoka A, Hayashi T, Kukitsu T, Takanashi K, Ishiwatari H, Abe T, Kogawa T, Takahashi M, Matsunaga T, Kato J.
- Journal Title
  
  Cancer Chemother Pharmacol 54 Suppl 1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in jurkat cells.2004
- Author(s)
  Sato T, Matsunaga T et al.
- Journal Title
  
  J Immunol 173
  
  Pages: 285-296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Thrombopoietin concentrations in peripheral blood correlated with platelet numbers in two patients with thrombocytopenia by chronic graft-versus-host disease.2003
- Author(s)
  Hirayama Y, Matsunaga T et al.
- Journal Title
  
  Am J Hematol 73
  
  Pages: 285-289
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Telomerized human multipotent mesenchymal cells can differentiate into hematopoietic and cobblestone area-supporting cells2003
- Author(s)
  Kobune M, Kawano Y, Ito Y, Chiba H, Nakamura K, Tsuda H, Sasaki K, Dehari H, Uchida H, Honmou O, Takahashi S, Bizen A, Takimoto R, Matsunaga T, Kato J, Kato K, Houkin K, Niitsu Y, Hamada H.
- Journal Title
  
  Exp Hematol 31
  
  Pages: 1-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Inhibition of type I procollagen production by tRNAValCTE-HSP47 ribozyme2003
- Author(s)
  Hagiwara S, Nakamura K, Hamada H, Sasaki K, Ito Y, Kuribayashi K, Sato T, Sato Y, Takahashi M, Kogawa K, Kato J, Terui T, Takayama T, Matsunaga T, Taira K, Niitsu Y.
- Journal Title
  
  J Gene Med 5
  
  Pages: 784-794
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Induction of PIG3 and NOXA through Acetylation of p53 at 320 and 373 Lysine Residues as a Mechanism for Apoptotic Cell Death by Histone Deacetylase Inhibitors.2003
- Author(s)
  Terui T, Matsunaga T et al.
- Journal Title
  
  Cancer Res 63
  
  Pages: 8948-8954
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Telomerized human multipotent mesenchymal cells can differentiate into hematopoietic and cobblestone area-supporting cells.2003
- Author(s)
  Kobune M, Matsunaga T et al.
- Journal Title
  
  Exp Hematol 31
  
  Pages: 1-8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Induction of PIG3 and NOXA through Acetylation of p53 at 320 and 373 Lysine Residues as a Mechanism for Apoptotic Cell Death by Histone Deacetylase Inhibitors2003
- Author(s)
  Terui T, Murakami K, Takimoto R, Takahashi M, Takada K, Murakami T, Minami S, Matsunaga T, Takayama T, Kato J, Niitsu Y.
- Journal Title
  
  Cancer Res 63
  
  Pages: 8948-8954
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Inhibition of type I procollagen production by tRNAVa1CTE-HSP47 ribozyme.2003
- Author(s)
  Hagiwara S, Matsunaga T et al.
- Journal Title
  
  J Gene Med 5
  
  Pages: 784-794
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Interaction between the leukemic cell VLA4 with stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia.2003
- Author(s)
  Matsunaga T, Takemoto N et al.
- Journal Title
  
  Nature Med 9
  
  Pages: 1158-1165
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Ex vivo expansion of human umbilical cord blood hematopoietic progenitor cells using a co-culture system with human telomerase catalytic subunit (hTERT) transfected human stromal cell.2003
- Author(s)
  Kawano Y, Matsunaga T et al.
- Journal Title
  
  Blood 101
  
  Pages: 532-540
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Ex vivo expansion of human umbilical cord blood hematopoietic progenitor cells using a co-culture system with human telomerase catalytic subunit (hTERT) transfected human stromal cell2003
- Author(s)
  Kawano Y, Kobune M, Yamaguchi M, Nakamura K, Ito Y, Sasaki K, Matsunaga T, Kato J, Chiba H, Ikebuchi K, Niitsu Y, Hamada H.
- Journal Title
  
  Blood 101
  
  Pages: 532-540
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Interaction between the leukemic cell VLA4 with stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia2003
- Author(s)
  Matsunaga T, Takemoto N, Sato T, Takimoto R, Tanaka I, Fujimi A, Akiyama T, Kuroda H, Kawano Y, Kobune M, Kato J, Hirayama Y, Sakamaki S, Kohda K, Miyake K, Niitsu Y.
- Journal Title
  
  Nature Med 9
  
  Pages: 1158-1165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Journal Article] Thrombopoietin concentrations in peripheral blood correlated with platelet numbers in two patients with thrombocytopenia by chronic graft-versus-host disease2003
- Author(s)
  Hirayama Y, Sakamaki S, Tsuji Y, Sagawa T, Chiba H, Matsunaga T, Kuroda H, Kusakabe T, Akiyama T, Kato J, Niitsu Y.
- Journal Title
  
  Am J Hematol 73
  
  Pages: 285-289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591014
[Presentation] VLA4とVLA5を介したフィブロネクチンへの接着は巨核球のproplatelet形成を促進する2010
- Author(s)
  松永卓也, 深井文雄, 久冨木庸子, 下田和哉, 他
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22591066
[Presentation] VLA4 と VLA5 を介したフィブロネクチンへの接着は巨核球の proplatelet 形成を促進する2010
- Author(s)
  松永卓也,深井文雄,久冨木庸子,下田和哉,他
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22591066
[Presentation] Ex vivo large-scale generation of human red blood cells from cord blood CD34^+ cells by co-culturing with macrophages2007
- Author(s)
  Matsunaga T, et. al.
- Organizer
  The 36th Annual Meeting of the International Society for Experimental Hematology
- Place of Presentation
  Hamburg,Genmany
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] Ex vivo large-scale generation of human red blood cells from cord blood CD34^+ cells by co-culturing with macrophages2007
- Author(s)
  Matsunaga, T., Fujimi, A
- Organizer
  The 36th Annual Meeting of the International Society for Experimental Hematology
- Place of Presentation
  Hamburg, Germany
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] Normal restoration of rat liver cirrhosis employing siRNA/HAP47 encapsulated in vitamin A liposomes2007
- Author(s)
  Sato, Y., Matsunaga, T
- Organizer
  The 17th APASL Conference
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] Wnt3/RhoA/ROCK signaling pathway is involved in VLA6-dependent adhesion-mediated drug resistance of multiple myeloma2007
- Author(s)
  Kobune, M., Matsunaga, T
- Organizer
  The 49th Annual Meeting of American Society of Hematology
- Place of Presentation
  Atlanta, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] Wnt3/RhoA/ROCK signaling pathway is involved in VLA6-dependent adhesion-mediated drug resistance of multiple myeloma2007
- Author(s)
  Kobune M, Matsunaga T.
- Organizer
  The 49th Annua lMeeting of American Societyof Hematology
- Place of Presentation
  Atlanta,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] A novel modality of cancer therapy targeting cancer stroma2007
- Author(s)
  Niitsu, Y., Matsunaga, T
- Organizer
  The Sixth Japan-China joint conference for cancer research
- Place of Presentation
  Toya, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] A novel modality of cancer therapy targeting cancer stroma2007
- Author(s)
  Niitsu Y, Matsunaga T.
- Organizer
  The Sixth Japan-China joint conference for cancer research
- Place of Presentation
  Toya,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] Normal restoration of rat cirrhosis employing siRNA/hap47 encapsulated in viramin A liposomes2007
- Author(s)
  Sato Y, Matsunaga T.
- Organizer
  The 17th APASL Conference
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] Combination therapy of anti-cancer drug with FNIII14 peptide of fibronectin effectively overcome cell adhesion mediated-drug resistance of acute myelogenous leukemia2006
- Author(s)
  Matsunaga, T., Fukai, F
- Organizer
  The 48th Annual Meeting of American Society of Hematology
- Place of Presentation
  Orland, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591076
[Presentation] Simultaneous Oral Session. Combination therapy of anti-cancer drug with FNIII14 peptide of fibronectin effectively overcome cell adhesion mediated-drug resistance of acute myelogenous leukemia2006
- Author(s)
  Matsunaga T, et. al.
- Organizer
  The 48th Annual Meeting of American Society of Hematology
- Place of Presentation
  Orland, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591076

1. SHIMODA Kazuya (90311844)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. FUKAI Fumio (90124487)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. SATO Tsutomu (40404602)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. KUBUKI Yohko (00284836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. NIITSU Yoshiro (10045502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IYAMA Satoshi (50398319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 今滝修 (60437697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUNAGA Takuya 松永 卓也

Research Projects

Research Products

Co-Researchers

HIF-1alpha阻害剤と抗癌剤を併用した新しい白血病幹細胞根絶療法の開発Principal Investigator

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Elucidation of chemoresistance in hypoxic condition and a developmentof radical treatment in AML cells by hypoxia specific inhibitory drugsPrincipal Investigator

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Development of transfusion products derived from hematopoietic stem cells using TNIII14 peptide

Principal Investigator

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Research Institution

急性骨髄性白血病の実践的治療モデルにおける抗癌剤/VLA-4阻害剤併用療法の検討Principal Investigator

Principal Investigator

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Review Section

Research Institution

Development of the system to produce large scale generation of human platelets from cord blood CD34^+ cells in vitroPrincipal Investigator

Principal Investigator

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Research Institution

フィブロネクチン由来ペプチドを用いた急性骨髄性白血病の新しい分子標的療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

造血器悪性腫瘍および骨転移性癌の骨随間質細胞との相互作用からみた抗癌剤抵抗性Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Development of the system to expand hematopoietic stem cells using gene modification techniquePrincipal Investigator

Principal Investigator

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Research Institution

ストローマ細胞との接着による急性白血病細胞の抗癌剤耐性誘導機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of hematopoietic stem cell transplantation using in vitro expanded bone marrow stromal cellsPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

[Journal Article] Elevated HIF-1α expression of acute myelogenous leukemia stem cells in the endosteal hypoxic zone may be a cause of minimal residual disease in bone marrow after chemotherapy2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated HIF-1expression of acute myelogenous leukemia stem cells in the endosteal hypoxic zone may be a cause of minimal residual disease in bone marrow after chemotherapy2012

Author(s)

Journal Title

Data Source

[Journal Article] Potentiated activation of VLA-4 and VLA-5 accelerates proplatelet-like formation.2012

Author(s)

Journal Title

Data Source

[Journal Article] Ex vivo large-scale generation of human red blood cells from cord blood CD34(+) cells by co-culturing with macrophages2008

Author(s)

Journal Title

MATSUNAGA Takuya 松永卓也