Shishido Takaaki 宍戸孝明

… Alternative Names

SHISHIDO Takaaki 宍戸孝明

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Researcher Number	70266500
Affiliation (Current)	2025: 東京医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 東京医科大学, 医学部, 教授 2010 – 2021: 東京医科大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 26040:Structural materials and functional materials-related Except Principal Investigator Orthopaedic surgery / Basic Section 90140:Medical technology assessment-related / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 生体環境劣化 / セラミック / インプラント / 低温劣化 / 構造健全性 / 複合セラミックス / エージング / 相転移 / ジルコニア強化型アルミナ / 人工股関節 … More / 残留応力 / 構造安定性 / 加速エージング / セラミック・インプラント / 人工股関節置換術 … More Except Principal Investigator 人工股関節 / 超高分子量ポリエチレン / 微細構造 / 高度架橋ポリエチレン / ラマン分光 / 細胞外マトリックス / ポリエチレン / 人工股関節置換術 / ポリエチレンライナー / デラミネーション耐性 / 微構造解析 / 脛骨インサート / 人工膝関節 / 血中金属濃度 / 摩耗 / 偽腫瘍 / 人工股関節摺動面 / 長期耐用性 / 耐疲労性 / 抗酸化性 / 耐摩耗性 / 衝撃疲労試験 / 寛骨臼ライナー / 低温劣化 / 構造健全性 / 残留応力 / 相変態 / 加速エージング / 複合セラミックス / 化学物理 / 分析科学 / 生体分子 / 生体材料 / I型コラーゲン / 膝靱帯 / 近赤外ラマン分光 / 組織変性 / 光バイオプシー / 組織診断 / 近赤外レーザー / 前十字靭帯 / 細胞内情報伝達 / 細胞外基質分解酵素 / 神経成長因子 / DUSP-1 / 神経侵入 / 軟骨変性 / 変形性関節症 / 人工関節 / 力学特性 / ビタミンＥ / ヒト軟骨 / クリープ / クリープ変形速度 / 超高分子ポリエチレン / 生体工学 / 人工股関節全置換術 / 股関節シュミレーター Less

人工股関節周囲組織反応(ALTR)の病態解明に関する基礎的および臨床的検討
- Principal Investigator
  
  石田常仁
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Tokyo Medical University
超長寿命型人工膝関節開発のためのデラミネーション破壊抑制に関する研究
- Principal Investigator
  
  高橋康仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Tokyo Medical University
高度架橋ポリエチレン製人工股関節の超長期耐用性の実現を目指した材料設計の至適化
- Principal Investigator
  
  立岩俊之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Tokyo Medical University
A novel proposal for validating the durability of ceramic-composite artificial hip joints and improving its prediction accuracy
- Principal Investigator
  
  TAKAHASHI Yasuhito
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Tokyo Medical University
Clarification of in-vivo fracture mechanisms of ceramic acetabular liner toward the safety improvementPrincipal Investigator
- Principal Investigator
  
  SHISHIDO Takaaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 26040:Structural materials and functional materials-related
- Research Institution
  Tokyo Medical University
A new diagnostic technology for degeneration of knee ligaments using Raman spectroscopy and its developmetnt toward practical applications
- Principal Investigator
  
  TAKAHASHI Yasuhito
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical University
Regulation of cartilage degeneration and innervation by DUSP-1 in the development of osteoarthritis
- Principal Investigator
  
  Sawaji Yasunobu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical University
Elucidation of the effects of antioxidant incorporation on molecular structure and mechanical properties in polyethylene hip joint prostheses
- Principal Investigator
  
  MASAOKA Toshinori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tokyo Medical University
Clarification of collagen degeneration mechanisms by NIR-Raman spectroscopy and development of a novel optical biopsy system
- Principal Investigator
  
  TAKAHASHI Yasuhito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical University
Effect of acetabular liner thickness on creep resistance in HXLPE for total joint replacement: deformation rate and molecular structure
- Principal Investigator
  
  YAMAMOTO Kengo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical University
Hip simulator study of wear characteristics of UHMWPE liner
- Principal Investigator
  
  YAMAMOTO Kengo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tokyo Medical University

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] A New Method for Diagnosing Biochemical Abnormalities of Anterior Cruciate Ligament (ACL) in Human Knees: A Raman Spectroscopic Study2019
- Author(s)
  Matsunaga R, Takahashi Y, Takahashi RH, Nagao T, Shishido T, Tateiwa T, Pezzotti G, Yamamoto K.
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 99 Pages: 284-294
- DOI
  10.1016/j.actbio.2019.09.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08524, KAKENHI-PROJECT-17K08705, KAKENHI-PROJECT-17K11029
[Journal Article] Size and thickness effect on creep deformation of conventional and vitamin E-diffused highly crosslinked UHMWPE in total hip arthroplasty2016
- Author(s)
  Yasuhito Takahashi , Toshiyuki Tateiwa, Takaaki Shishido, Toshinori Masaoka, Kosuke Kubo, Kengo Yamamoto
- Journal Title
  
  Journal of the Mechanical Behavior of Biomedical Materials
  
  Volume: 印刷中 Pages: 399-406
- DOI
  10.1016/j.jmbbm.2016.05.020
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462383
[Journal Article] Improved resistance to neck-liner impingement in second-generation highly crosslinked polyethylene - The role of vitamin E and crosslinks2016
- Author(s)
  Takahashi Y, Tateiwa T, Pezzotti G, Shishido T, Masaoka T, Yamamoto K
- Journal Title
  
  The Journal of Arthroplasty
  
  Volume: 31 Issue: 12 Pages: 2926-2932
- DOI
  10.1016/j.arth.2016.05.049
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01316
[Journal Article] 変形性関節症に対する薬物治療の展望2016
- Author(s)
  澤地恭昇，宮本泰典，依藤麻紀子，正岡利紀，宍戸孝明，山本謙吾
- Journal Title
  
  整形・災害外科
  
  Volume: 59 Pages: 1181-1188
- Data Source
  KAKENHI-PROJECT-16K10840
[Journal Article] Do formalin fixation and freeze-thaw affect near-infrared Raman spectroscopy of cartilaginous tissue? - An ex vivo analysis of native human articular cartilage2015
- Author(s)
  Yasuhito Takahashi, Takaaki Shishido, Kengo Yamamoto, Yasunobu Sawaji, Jun NIshida, Giuseppe Pezzotti
- Journal Title
  
  Journal of Raman Spectroscopy
  
  Volume: 46 Issue: 11 Pages: 1166-1172
- DOI
  10.1002/jrs.4748
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462320
[Journal Article] Vitamin-E blended and infused highly cross-linked polyethylene for total hip arthroplasty: A comparison of three-dimensional crystalline morphology and strain recovery behavior2014
- Author(s)
  Yasuhito Takahashi, Toshinori Masaoka, Kengo Yamamoto, Takaaki Shishido, Toshiyuki Tateiwa, Kosuke Kubo, Giuseppe Pezzotti
- Journal Title
  
  Journal of the mechanical behavior of biomedical materials
  
  Volume: 36 Pages: 59-70
- DOI
  10.1016/j.jmbbm.2014.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462383
[Presentation] ヒト前十字靭帯の非侵襲診断に向けた近赤外レーザーラマン分光の応用2019
- Author(s)
  松永怜、高橋康仁、高橋礼典、長尾俊孝、宍戸孝明、正岡利紀、立岩俊之、山本謙吾
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11029
[Presentation] DUSP-1 Involves In The Mechanism Of PGE2 Suppression Of MMPs And NGF In Human Synovial Cells2018
- Author(s)
  Asato Maekawa, Yasunobu Sawaji, Kenji Endo, Takuya Kusakabe, Takamitu Konishi, Toshiyuki Tateiwa, Toshinori Masaoka, Takaaki Shishido, Kengo Yamamoto
- Organizer
  The 28th Japanese-Korean Combined Orthopaedic Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10840
[Presentation] DUSP-1によるヒト変形性関節症の軟骨変性および神経侵入制御の解明2018
- Author(s)
  前川麻人，澤地恭昇，遠藤健司，日下部拓哉，小西隆允，正岡利紀，宍戸孝明，山本謙吾
- Organizer
  第11回日本運動器疼痛学会
- Data Source
  KAKENHI-PROJECT-16K10840
[Presentation] ヒト関節滑膜細胞におけるPGE2によるNGFおよびMMP発現抑制へのDUSP1の関与2018
- Author(s)
  前川麻人，澤地恭昇，遠藤健司，日下部拓哉，小西隆允，正岡利紀，宍戸孝明，山本謙吾
- Organizer
  第16回整形外科痛みを語る会
- Data Source
  KAKENHI-PROJECT-16K10840
[Presentation] 高度架橋ポリエチレン摺動面の現況と展望 - 1st vs. 2nd generation2017
- Author(s)
  髙橋康仁、宍戸孝明、正岡利紀、立岩俊之、Giuseppe Pezzotti、山本謙吾
- Organizer
  第44回日本股関節学会学術集会
- Data Source
  KAKENHI-PROJECT-15K01316
[Presentation] Vitamin E混合は高架橋UHMWPEライナーの微細構造および力学挙動に影響するのか？2016
- Author(s)
  高橋康仁、Giuseppe Pezzotti、宍戸孝明、正岡利紀、立岩俊之、久保宏介、山本謙吾
- Organizer
  第46回日本人工関節学会
- Place of Presentation
  グランフロント大阪
- Year and Date
  2016-02-26
- Data Source
  KAKENHI-PROJECT-25462383
[Presentation] Vitamin E混合は高架橋UHMWPEライナーの微細構造および力学挙動に影響するのか？2016
- Author(s)
  高橋康仁、Giuseppe Pezzotti、宍戸孝明、正岡利紀、立岩俊之、久保宏介、山本謙吾
- Organizer
  第46回日本人工関節学会
- Place of Presentation
  グランフロント大阪
- Year and Date
  2016-02-26
- Data Source
  KAKENHI-PROJECT-15K01316
[Presentation] 変形性関節症の病態形成過程における選択的COX-2阻害剤の有用性の相違2016
- Author(s)
  澤地恭昇，依藤麻紀子，宮本泰典，立岩俊之，正岡利紀，宍戸孝明，山本謙吾
- Organizer
  第31回　日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K10840

1. YAMAMOTO Kengo (10246316)

# of Collaborated Projects: 11 results

# of Collaborated Products: 13 results
2. MASAOKA Toshinori (70256270)

# of Collaborated Projects: 10 results

# of Collaborated Products: 11 results
3. TATEIWA Toshiyuki (00424630)

# of Collaborated Projects: 10 results

# of Collaborated Products: 9 results
4. TAKAHASHI Yasuhito (60567668)

# of Collaborated Projects: 9 results

# of Collaborated Products: 7 results
5. Sawaji Yasunobu (20571152)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. 久保宏介 (40408092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 遠藤健司 (90266479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 松永怜 (90459579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 香取庸一 (40233837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石田常仁 (10453721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MAEKAWA Asato

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 高橋礼典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shishido Takaaki 宍戸 孝明

SHISHIDO Takaaki 宍戸 孝明

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[Journal Article] A New Method for Diagnosing Biochemical Abnormalities of Anterior Cruciate Ligament (ACL) in Human Knees: A Raman Spectroscopic Study2019

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[Journal Article] Size and thickness effect on creep deformation of conventional and vitamin E-diffused highly crosslinked UHMWPE in total hip arthroplasty2016

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[Journal Article] Improved resistance to neck-liner impingement in second-generation highly crosslinked polyethylene - The role of vitamin E and crosslinks2016

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[Journal Article] 変形性関節症に対する薬物治療の展望2016

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Shishido Takaaki 宍戸孝明

SHISHIDO Takaaki 宍戸孝明