Hirata Keiji 平田敬治

… Alternative Names

平田敬治ヒラタケイジ

Keiji Hirata 平田敬治

HIRATA Keiji 平田敬治

HIRATA K 平田敬治

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Researcher Number	70269059
Other IDs
Affiliation (Current)	2025: 産業医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 産業医科大学, 医学部, 教授 2017 – 2019: 産業医科大学, 医学部, 教授 2009 – 2010: International University of Health and Welfare, 保健医療学部, 准教授 2008: University of Occupational and Environmental Health, Japan, 医学部, 講師 2007: University of Occupational&Environmental Health, Sch. of Med., Assistant Prof. 2006: 産業医科大学, 医学部, 助手 1994 – 1996: UOEH,Assistant, 医学部, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery / Digestive surgery / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator ヒアルロン酸 / 膵癌 / 癌微小環境 / 低酸素 / 細胞シグナル / 浸潤 / KIAA1199 / 癌 / 抗癌剤 / イノシトール3リン酸受容体 … More / アポトーシス / 細胞増殖 / 大腸癌 / IP3レセプター / カルシウムシグナリング … More Except Principal Investigator ヒアルロン酸 / 膵癌 / Trinitrobenzene sulfonic acid / Indomethacin / 大腸癌 / アポトーシス / 細胞増殖 / IP3レセプター / カルシウムシグナリング / 浸潤 / 癌 / apoptosis / calcium signaling / cell proliferation / colorectal cancer / IP3 receptor / E-cadherin / Siaryl Lewis^a / c-met / matrix metalloproteinase / plasminogen activator / metastasis / endothelial cell / invasion assay / マトリックス・メタロプロティナーゼ / 接着分子 / 肝細胞増殖因子受容体 / マトリックス・メタロプロテイナーゼ / プラスミノーゲン・アクチベータ- / 転移 / 血管内皮細胞 / 癌浸潤アッセイ / Fibronectin / Herbicide / Epithelial cell proliferation / 1,2-Dimethyl hydrazine / Experimental colon cancer / Colon cancer / Captan / 2,4-Phenoxy acetic acid / 発癌プロモーター作用 / 1,2-dimethy1 hydrazine / Fifronectin / 農薬 / 上皮細胞増殖活性能 / 1、2-Dimethyl hydrazine / 実験大腸癌 / イノシトール3リン酸受容体 / 胃癌 Less

Hyaluronan activated-metabolism phenotype and Hippo signaling in the progression of pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  平田敬治
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Role of TMEM2, a hyaluronidase, in pancreatic cancer progression under microenvironmental stress
- Principal Investigator
  
  佐藤典宏
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Personalized treatment strategy for pancreatic cancer targeting hyaluronan metabolism
- Principal Investigator
  
  Sato Norihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
Role of KIAA1199, a novel hyaluronidase, in the aggressive progression of pancreatic ductal adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  Keiji Hirata
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
The role of InsP3 receptor expression in gastric cancer patients
- Principal Investigator
  
  SHIBAO Kazunori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
The role of InsP3 receptor expression in colorectal cancer patients and its relation to metastasis and neo-adjuvant chemotherapyPrincipal Investigator
- Principal Investigator
  
  HIRATA Keiji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
EXPRESSION OF THE TYPE III INOSITOL 1, 4, 5 TRIPHOSPHATE RECEPTOR IS A NOVEL MARKER TO EVALUATE MALIGNANT POTENTIAL IN COLORECTAL CARCINOMA
- Principal Investigator
  
  SHIBAO Kazunori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Occupational and Environmental Health, Japan
Investigation of the metastatic mechanism by a new in vitro invasion asseay using monolayrs of vascular endothelial cells.
- Principal Investigator
  
  ITOH Hideaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Occupational and Environmental Health
Effect of environmental factors on risk of bowel cancer. ; agricultrual chemicals and colon cancer
- Principal Investigator
  
  ITOH Hedeaki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Occupational and Environmental Health

All 2019 2018 2017 2010 Other

All Journal Article Presentation Other

[Journal Article] 【膵癌研究Cutting Edge-from Carcinogenesis to Metastatic Colonization-】Hyaluronan(ヒアルロン酸)を中心としたMicroenvironmentからみた膵癌進展機構2017
- Author(s)
  佐藤典宏, 厚井志郎, 天池孝夫, 工藤遊山, 古賀敦大, 又吉信貴, 平田敬治
- Journal Title
  
  肝胆膵
  
  Volume: 75 Pages: 821-829
- Data Source
  KAKENHI-PROJECT-17K10714
[Journal Article] KIAA1199/CEMIP/HYBID overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma.2017
- Author(s)
  Koga A, Sato N, Kohi S, Yabuki K, Cheng XB, Hisaoka M, Hirata K
- Journal Title
  
  Pancreatology
  
  Volume: 17 Pages: 115-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10715
[Journal Article] 【膵癌研究Cutting Edge-from Carcinogenesis to Metastatic Colonization-】Hyaluronan(ヒアルロン酸)を中心としたMicroenvironmentからみた膵癌進展機構2017
- Author(s)
  佐藤典宏, 厚井志郎, 天池孝夫, 工藤遊山, 古賀敦大, 又吉信貴, 平田敬治
- Journal Title
  
  肝胆膵
  
  Volume: 75 Pages: 821-829
- Data Source
  KAKENHI-PROJECT-17K10715
[Journal Article] KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.2017
- Author(s)
  Kohi S, Sato N, Koga A, Matayoshi N, Hirata K
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 17156-17163
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10714
[Journal Article] KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.2017
- Author(s)
  Kohi S, Sato N, Koga A, Matayoshi N, Hirata K
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 17156-17163
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10715
[Journal Article] The type III inositol 1, 4, 5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma2010
- Author(s)
  Shibao K., Hirata K, Yamaguchi K., et al.
- Journal Title
  
  Cell Calcium
  
  Volume: 48 Pages: 315-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591583
[Journal Article] The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma2010
- Author(s)
  Shibao K., Hirata K, Yamaguchi K., et al.
- Journal Title
  
  Cell Calcium
  
  Volume: 48 Pages: 315-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591598
[Journal Article] The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma2010
- Author(s)
  Shibao K, Fiedler MJ, Nagata J, Minagawa N, Hirata K, Nakayama Y, Iwakiri Y, Nathanson MH, Yamaguchi K
- Journal Title
  
  Cell Calcium 48(6)
  
  Pages: 315-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591598
[Journal Article] The type III inositol 1,4,5-trisphosphate receptor is associated with aggressiveness of colorectal carcinoma.2010
- Author(s)
  Shibao K, Fiedler MJ, Nagata J, Minagawa N, Hirata K, Nakayama Y, Iwakiri Y, Nathanson MH, Yamaguchi K
- Journal Title
  
  Cell Calcium. 48(6)
  
  Pages: 315-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591583
[Presentation] 浸潤性膵癌におけるヒアルロン酸代謝亢進フェノタイプ(HAMP)2019
- Author(s)
  佐藤典宏, 工藤遊山, 天池孝夫, 安達保尋, 大場拓哉, 古賀敦大, 平田敬治
- Organizer
  日本癌学会総会（78回）
- Data Source
  KAKENHI-PROJECT-17K10715
[Presentation] 浸潤性膵癌におけるヒアルロン酸代謝亢進フェノタイプ(HAMP)2019
- Author(s)
  佐藤典宏, 工藤遊山, 天池孝夫, 安達保尋, 大場拓哉, 古賀敦大, 平田敬治
- Organizer
  日本癌学会総会（78回）
- Data Source
  KAKENHI-PROJECT-17K10714
[Presentation] 膵癌における新たなフェノタイプ　ヒアルロン酸代謝亢進フェノタイプ(HAMP)の同定2019
- Author(s)
  佐藤典宏, 工藤遊山, 天池孝夫, 安達保尋, 古賀敦大, 平田敬治
- Organizer
  日本消化器外科学会総会 74回
- Data Source
  KAKENHI-PROJECT-17K10714
[Presentation] 膵癌における炎症とマイクロRNAのKIAA1199発現や細胞遊走への関与2019
- Author(s)
  古賀敦大, 厚井志郎, 大場拓哉, 安達保尋, 天池孝夫, 工藤遊山, 柴尾和徳, 平田敬治, 佐藤典宏
- Organizer
  日本癌学会総会（78回）
- Data Source
  KAKENHI-PROJECT-17K10714
[Presentation] 膵癌における新たなフェノタイプ　ヒアルロン酸代謝亢進フェノタイプ(HAMP)の同定2019
- Author(s)
  佐藤典宏, 工藤遊山, 天池孝夫, 安達保尋, 古賀敦大, 平田敬治
- Organizer
  日本消化器外科学会総会 74回
- Data Source
  KAKENHI-PROJECT-17K10715
[Presentation] 膵癌における炎症とマイクロRNAのKIAA1199発現や細胞遊走への関与2019
- Author(s)
  古賀敦大, 厚井志郎, 大場拓哉, 安達保尋, 天池孝夫, 工藤遊山, 柴尾和徳, 平田敬治, 佐藤典宏
- Organizer
  日本癌学会総会（78回）
- Data Source
  KAKENHI-PROJECT-17K10715
[Presentation] ヒアルロン酸代謝亢進フェノタイプ(HAMP)は膵癌の新たな予後因子・治療標的となる2019
- Author(s)
  佐藤典宏, 工藤遊山, 天池孝夫, 安達保尋, 古賀敦大, 平田敬治
- Organizer
  日本外科学会定期学術集会 119回
- Data Source
  KAKENHI-PROJECT-17K10714
[Presentation] 浸潤性膵癌における新規ヒアルロン酸分解酵素TMEM2の発現および機能解析2019
- Author(s)
  工藤遊山, 大場拓哉, 安達保尋, 天池孝夫, 古賀敦大, 佐藤典宏, 平田敬治
- Organizer
  日本癌学会総会（78回）
- Data Source
  KAKENHI-PROJECT-17K10715
[Presentation] ヒアルロン酸代謝亢進フェノタイプ(HAMP)は膵癌の新たな予後因子・治療標的となる2019
- Author(s)
  佐藤典宏, 工藤遊山, 天池孝夫, 安達保尋, 古賀敦大, 平田敬治
- Organizer
  日本外科学会定期学術集会 119回
- Data Source
  KAKENHI-PROJECT-17K10715
[Presentation] 浸潤性膵癌における新規ヒアルロン酸分解酵素TMEM2の発現および機能解析2019
- Author(s)
  工藤遊山, 大場拓哉, 安達保尋, 天池孝夫, 古賀敦大, 佐藤典宏, 平田敬治
- Organizer
  日本癌学会総会（78回）
- Data Source
  KAKENHI-PROJECT-17K10714
[Presentation] 膵癌におけるKIAA1199の発現調節メカニズム　炎症およびマイクロRNAの関与2018
- Author(s)
  古賀敦大, 厚井志郎, 佐藤典宏, 天池孝夫, 工藤遊山, 又吉信貴, 柴尾和徳, 平田敬治
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-17K10715
[Presentation] 膵癌悪性化における低分子ヒアルロン酸の役割と分解酵素をターゲットにした新規治療2018
- Author(s)
  佐藤典宏, 厚井志郎, 古賀敦大, 又吉信貴, 天池孝夫, 工藤遊山, 平田敬冶
- Organizer
  第49回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-17K10714
[Presentation] 膵癌におけるヒアルロン酸分解酵素KIAA1199/CEMIPを調節するmiR-216aの新たなメカニズム2018
- Author(s)
  古賀敦大, 佐藤典宏, 厚井志郎, 天池孝夫, 工藤遊山, 又吉信貴, 柴尾和徳, 平田敬治
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10715
[Presentation] 浸潤性膵癌におけるヒアルロン酸レセプターRHAMM の発現および機能解析2018
- Author(s)
  佐藤典宏, 厚井志郎, 古賀敦大, 工藤遊山, 天池孝夫, 又吉信貴, 平田敬治
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10714
[Presentation] 膵癌におけるヒアルロン酸代謝亢進フェノタイプの同定と治療ターゲットとしての可能性2018
- Author(s)
  佐藤典宏、厚井志郎、古賀敦大, 工藤遊山, 安達保尋、天池孝夫、又吉信貴、平田敬冶
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10714
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1. Sato Norihiro (20423527)

# of Collaborated Projects: 4 results

# of Collaborated Products: 20 results
2. SHIBAO Kazunori (10330987)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. NAGATA Naoki (80200377)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. ITOH Hedeaki (90038852)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YAMAGUCHI Koji (50191226)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. KURODA Y (30131915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAKAYAMA Yoshifumi (50279337)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hirata Keiji 平田 敬治

平田 敬治 ヒラタ ケイジ

Keiji Hirata 平田 敬治

HIRATA Keiji 平田 敬治

HIRATA K 平田 敬治

Research Projects

Research Products

Co-Researchers

Hyaluronan activated-metabolism phenotype and Hippo signaling in the progression of pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of TMEM2, a hyaluronidase, in pancreatic cancer progression under microenvironmental stress

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Personalized treatment strategy for pancreatic cancer targeting hyaluronan metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of KIAA1199, a novel hyaluronidase, in the aggressive progression of pancreatic ductal adenocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of InsP3 receptor expression in gastric cancer patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of InsP3 receptor expression in colorectal cancer patients and its relation to metastasis and neo-adjuvant chemotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EXPRESSION OF THE TYPE III INOSITOL 1, 4, 5 TRIPHOSPHATE RECEPTOR IS A NOVEL MARKER TO EVALUATE MALIGNANT POTENTIAL IN COLORECTAL CARCINOMA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the metastatic mechanism by a new in vitro invasion asseay using monolayrs of vascular endothelial cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of environmental factors on risk of bowel cancer. ; agricultrual chemicals and colon cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 【膵癌研究Cutting Edge-from Carcinogenesis to Metastatic Colonization-】Hyaluronan(ヒアルロン酸)を中心としたMicroenvironmentからみた膵癌進展機構2017

Author(s)

Journal Title

Data Source

[Journal Article] KIAA1199/CEMIP/HYBID overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma.2017

Author(s)

Journal Title

Data Source

[Journal Article] 【膵癌研究Cutting Edge-from Carcinogenesis to Metastatic Colonization-】Hyaluronan(ヒアルロン酸)を中心としたMicroenvironmentからみた膵癌進展機構2017

Author(s)

Journal Title

Data Source

[Journal Article] KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.2017

Author(s)

Journal Title

Data Source

[Journal Article] KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.2017

Author(s)

Hirata Keiji 平田敬治

平田敬治ヒラタケイジ

Keiji Hirata 平田敬治

HIRATA Keiji 平田敬治

HIRATA K 平田敬治

[Presentation] 膵癌における新たなフェノタイプ　ヒアルロン酸代謝亢進フェノタイプ(HAMP)の同定2019

[Presentation] 膵癌における新たなフェノタイプ　ヒアルロン酸代謝亢進フェノタイプ(HAMP)の同定2019

[Presentation] 膵癌におけるKIAA1199の発現調節メカニズム　炎症およびマイクロRNAの関与2018