Shimizu Shigeomi 清水重臣

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SHIMIZU Shigeomi 清水重臣

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Researcher Number	70271020
Other IDs	https://orcid.org/0000-0002-8437-0791
External Links
Affiliation (Current)	2026: 東京科学大学, 総合研究院, 特任教授
Affiliation (based on the past Project Information) *help	2024 – 2026: 東京科学大学, 総合研究院, 特任教授 2022 – 2024: 東京医科歯科大学, 高等研究院, 特別教授 2023: 東京工業大学, 総合研究院, 特任教授 2006 – 2022: Tokyo Medical and Dental University, Medical Research Institute, Professor, 難治疾患研究所, 教授 1999 – 2005: Osaka University Graduate School of Medicine, Assistant Professor, 医学系研究科, 助教授 2002: 大阪大学, 医学研究科, 助教授 1996 – 1998: Osaka University Medical School, Assistant Professor, 医学部, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Biological Sciences / Pathological medical chemistry / Transformative Research Areas, Section (III) / Broad Section H / General medical chemistry / Functional biochemistry / Complex systems / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Pathological medical chemistry / Cell biology / Digestive surgery … More Except Principal Investigator … More General surgery / Digestive surgery / 細胞死(アポトーシス) / Digestive surgery / Molecular biology / Thoracic surgery / General surgery / Biological Sciences Less
Keywords	Principal Investigator ミトコンドリア / アポトーシス / オートファジー / ゴルジ体 / Bcl-2 / GOMED / 神経変性疾患 / Bax / Atg5 / 小胞体 … More / 細胞生物 / 超解像顕微鏡 / オルガネラ / Ulk1 / ネクローシス / 発癌 / ストレス / 生体分子 / シグナル伝達 / リガンド / 糖鎖 / 受容体 / SCLIM / ゾーン / 細胞・組織 / 新規オートファジー / ATG5 / Tat-BH4 / VDAC / mitochondria / apoptosis / ケミカルバイオロジー / Bak / 癌 / Atg5非依存的オートファジー / Atg5非依存性 / 生体膜 / 電子顕微鏡 / 低分子化合物 / 貧血 / 遺伝学 / Omi / 寿命 / タンパク質 / タンパク質寿命 / SICM / 小胞輸送 / タンパク質分解 / PI4P / Flad / RIPK3 / エンドソーム / 老化 / 神経科学 / 認知症 / Atg5非依存的 / 実験病理学 / 脳老化変性タンパク質 / 脳老化 / 神経変性 / cell death / autophagy / Beclin1 / 細胞死 / aptosis / BH4 / cytochrome c / シトクロムc / Yama) / caspase-3(CPP32 / cpp32 / yama / cpp32) / caspase-3(yama / 細胞分化 / bak / bax / 細胞情報伝達機構 / 血液疾患 / 細胞リモデリング / オートファジー病 / alternative macroautophagy / 発生 / がん / BH3 / 膜透過性 / alternative macroautohagy / 蛋白質スプライシング / Bc1-2 / Smac / カスペース / permeability transition / サイクロフィリン / パーキンソン病 / mnd2 / 膜透過性亢進現象 / サイクロフィリンD / 放射線 / 膜透過性亢進 / シトクロムC / Bik / Bid … More Except Principal Investigator アポトーシス / bcl-2 / ミトコンドリア / apoptosis / Bcl-2 / Th1 / 炎症性腸疾患 / FK506 / CTLA4Ig / Fas Ligand / CTLA4-Ig / アデノウイルスベクター / hypoxia / HIF-1 / VEGF / p53 / mitochondria / ICE / オートファジー / Smooth muscle cell / Atherosclerosis / Apoptosis / PTP / Bcl-2ファミリー / 平滑筋細胞 / 動脈硬化 / Intestinal epithelium / Bcl transgenic mouse / IL-10 knock out mouse / Inflammatory Bowel Disease / 消化管上皮 / ->マウス / IL-10^<- / 腸管上皮 / Bcl-2トランスジェニックマウス / IL-10ノックアウトマウス / adenoviral vector / Islet / CTL4Ig / 膵島 / NKT cells / IDDM / BB-rat / islet / 膵島移植 / インスリン依存型糖尿病 / NKT細胞 / BBラット / インスリン依存型糖尿病(IDDM) / Fas ligand / HVJリポソーム / 膵・膵島移植 / dominant negative / caspase / Bc1-2 / 凍結保存 / 心筋保護 / 心筋虚血 / 虚血再灌流傷害 / ナノバブル水 / APG5 / Becline / Acinus / DNA傷害 / シトクロムc / カスペース / プログラム細胞死 / 核 / CPP-32 / necrosis / 無酸素障害 Less

生体におけるゴルジ体関連分解GOMEDの役割と関連疾患Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2026 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section H
- Research Institution
  Institute of Science Tokyo
Changes in biological responses caused by qualitative differences in self-recognition receptorsPrincipal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Science Tokyo
Analysis of the Mechanism of Protein Lifetime Determination in the Golgi apparatusPrincipal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Science Tokyo
Biological role of GOMED and related diseasesPrincipal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section H
- Research Institution
  Institute of Science Tokyo
  Tokyo Medical and Dental University
Alteration of Biological Responses by Different Qualities of Self-Recognition ReceptorsPrincipal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Institute of Science Tokyo
細胞機能を司るオルガネラ・ゾーンの解読Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
第２のマクロオートファジーGOMEDの生体での役割Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Novel role of Golgi apparatus for non-cell autonomous eventsPrincipal Investigator
- Principal Investigator
  
  Shimizu Shigeomi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Tokyo Medical and Dental University
The effects of Atg5-independent autophagy activator on DSS-induced colitis in mice
- Principal Investigator
  
  Matsuda Chu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Regulation of brain aging by alternative autophagyPrincipal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Analysis of "Response zone" and " Communication zone" in mitochondria and Golgi apparatusPrincipal Investigator
- Principal Investigator
  
  shimizu shigeomi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Toward an integrative understanding of functional zones in organellesArea Organizer
- Area Organizer
  
  清水重臣
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Toward an integrative understanding of functional zones in organellesPrincipal Investigator
- Principal Investigator
  
  Shimizu Shigeomi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Biological roles of novel proteolytic mechanism GOMEDPrincipal Investigator
- Principal Investigator
  
  shimizu shigeomi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Development of small compounds that induce alternative autophagyPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
新規オートファジーによる脳老化タンパク質調節機構の解析と創薬開発研究Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Development of autophagy visualization tools and analyses of physiological roles of autophagyPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
ミトコンドリア膜上に一過性に形成される過渡的細胞死孔の捕捉Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
Structural analysis of mitochondrial apoptotic porePrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Medical and Dental University
新しく発見したオートファジー機構を介した蛋白質品質管理システムの解析Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
ミトコンドリア膜上に一過性に形成される過渡期細胞死孔の捕捉Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Medical and Dental University
Studies of alternative macroautophagy and its application for "Autophagic Diseases"Principal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
新しく発見したオートファジーを基盤とした細胞内浄化システムの包括的理解Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Medical and Dental University
アポトーシスを可視化するマウスの開発とその応用Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
酸素ナノバブル水の細胞機能保護効果の解明、特に心臓保存への応用に関する研究Principal Investigator
- Principal Investigator
  
  清水重臣, 田中啓之
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Tokyo Medical and Dental University
ミトコンドリアストレスを介した神経変性疾患の分子機構解明とその治療Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
ミトコンドリアストレスを介した神経変性疾患の分子機構解明とその治療Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
発癌におけるオートファジー様細胞死の役割とそれを応用した分子標的治療法の開発
- Principal Investigator
  
  長谷川順一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Analysis of biological role and molecular mechanisms of autophagic cell deathPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
  Osaka University
ミトコンドリア膜透過性亢進機構を標的とした抗アポトーシス薬の開発Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Regulation of Intestinal Mucosal Immunity in a Mouse Model on Inflammatory Bowel Disease
- Principal Investigator
  
  ITO Toshinori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Study of the molecular mechanism and clinical implication of a novel apoptosis gene
- Principal Investigator
  
  YASUDA Osamu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  細胞死(アポトーシス)
- Research Institution
  Osaka University
ミトコンドリア膜透過性亢進機構を標的とした抗アポトーシス薬の開発Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
アポトーシスにおけるミトコンドリア膜透過性亢進因子の同定とその分子機構の解明Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Development of anti-and pro-apoptotic drugs via regulation of VDAC, a mitochondrial outermembrane proteinPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
アポトーシスにおけるミトコンドリア膜透過性亢進因子の同定とその分子機構の解明Principal Investigator
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Research for immuno-logical tolerance induction in islet xeno-transplantation -Therapeutic effect of a adenovirus or retrovirus mediated CTLA4Ig gene transfer combined with immunosuppressive regents-
- Principal Investigator
  
  NAKATA Seizou
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Identification of novel cytochrome c releasing factor and analysis of its molecular function on apoptosisPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
アポトーシスにおける細胞質から核への情報伝達メカニズム
- Principal Investigator
  
  辻本賀英
- Project Period (FY)
  1999 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
The induction of a donor-specific tolerance in islet xenotransplantation models by Bcl-2/Fas ligand transfection combined with immunosuppressive agents .
- Principal Investigator
  
  NAKATA Seizou
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Development of novel cancer gene therapy using HIF-1 gene
- Principal Investigator
  
  YUMIBA Takeyoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
Study of molecular basis of apoptosis using in vitro system
- Principal Investigator
  
  TSUJIMONOTO Yoshihide
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
Novel cancer gene therapy using apoptosis-related genePrincipal Investigator
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Osaka University
肝虚血障害機構の遺伝学的解明と細胞死抑制遺伝子bc1−2導入による保護
- Principal Investigator
  
  上池渉
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
STUDY OF APOPTOSIS IN VITRO CELL-FREE SYSTEM
- Principal Investigator
  
  TSUJIMOTO Yoshihide
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University Medical School

[Book] Innovative Medicine : Basic Research and Development2015
- Author(s)
  Shimizu S
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-25670139
[Book] Innovative Medicine : Basic Research and Development2015
- Author(s)
  Shimizu S
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-22229002
[Book] Innovative Medicine : Basic Research and Development2015
- Author(s)
  shimizu S
- Total Pages
  339
- Publisher
  Springer Press
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014
- Author(s)
  S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida.
- Total Pages
  250
- Publisher
  Academic Press,
- Data Source
  KAKENHI-PROJECT-22229002
[Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014
- Author(s)
  S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida.
- Total Pages
  250
- Publisher
  Academic Press,
- Data Source
  KAKENHI-PUBLICLY-24121708
[Book] AUTOPHAGY: Cancer, Other Pathologies, Inflammation, Immunity, and Infection.Vol. 22014
- Author(s)
  Shimizu S, Arakawa S, Nishida Y, Yamaguchi H, Yoshida T
- Total Pages
  250
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-25670139
[Book] アポトーシス調節系「分子標的薬」日本臨床2012
- Author(s)
  清水重臣
- Data Source
  KAKENHI-PROJECT-23657084
[Book] 細胞死解析プロトコール2011
- Author(s)
  清水重臣
- Total Pages
  223
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22229002
[Book] 細胞死解析プロトコール2011
- Author(s)
  清水重臣
- Total Pages
  223
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23657084
[Book] 細胞死解析プロトコール2011
- Author(s)
  清水重臣
- Total Pages
  223
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-22121505
[Book] 細胞死解析プロトコール2011
- Author(s)
  清水重臣
- Total Pages
  223
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-22020009
[Book] からだと酸素の事典2009
- Author(s)
  清水重臣
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-19659349
[Book] 神経変性疾患のサイエンス2007
- Author(s)
  清水重臣
- Total Pages
  247
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18023024
[Book] 細胞死・アポトーシス集中マスター2005
- Author(s)
  清水重臣
- Total Pages
  130
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390094
[Book] Mammalian autophagy can occur through an Atg5/Atg7- independent pathway. AUTOPHAGY: Cancer, Other Pathologies
- Author(s)
  S. Shimizu, S. Arakawa, Y. Nishida, H. Yamaguchi, T. Yoshida
- Publisher
  Inflammation, Immunity, and Infection(印刷中)
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Novel cell-to-cell communications between macrophages and fibroblasts regulate obesity-induced adipose tissue fibrosis2025
- Author(s)
  Kohda H,Tanaka M,Shichino S、Arakawa S、Komori T、Ito A、Wada E、Ochi K、Yuan X、Takeda T、Saiki A、Tatsuno I、Ikeda K、Miyai Y、Enomoto A、Morikawa Y、Shimizu S、Ueha S、Matsushima K、Ogawa Y、Suganami T
- Journal Title
  
  Diabetes
  
  Volume: 10 Issue: 7 Pages: 1-1
- DOI
  10.2337/db24-0762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04773, KAKENHI-PUBLICLY-23H04776, KAKENHI-PUBLICLY-24H01887, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-22K11700, KAKENHI-PROJECT-22K19524, KAKENHI-PROJECT-23K14591, KAKENHI-PROJECT-23K27377, KAKENHI-PROJECT-24K02052, KAKENHI-PROJECT-24K10076, KAKENHI-PROJECT-24KK0150
[Journal Article] ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney disease2024
- Author(s)
  Yanagi T、Kikuchi H、Takeuchi K、Susa K、Mori T、Chiga M、Yamamoto K、Furukawa A、Kanazawa T、Kato Y、Takahashi N、Suzuki T、Mori Y、Carter B.、Mori M、Nakano Yu、Fujiki T、Hara Y、Suzuki S、Ando F、Mandai S、Honda S、Torii S、Shimizu S、Tanaka H、Fujii Y、Rai T、Uchida S、Sohara E
- Journal Title
  
  Kidney International
  
  Volume: 106 Issue: 5 Pages: 887-906
- DOI
  10.1016/j.kint.2024.08.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04773, KAKENHI-PUBLICLY-24H01887, KAKENHI-PROJECT-23K24346, KAKENHI-PROJECT-22K07345, KAKENHI-PROJECT-23K19610, KAKENHI-PROJECT-24K02465, KAKENHI-PROJECT-23K05748, KAKENHI-PROJECT-24K11426, KAKENHI-PROJECT-24K11434, KAKENHI-PROJECT-24K22093, KAKENHI-PROJECT-24K19143
[Journal Article] Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes2024
- Author(s)
  Hasegawa Tatsuya、Noguchi Saori、Nakashima Masaya、Miyai Masashi、Goto Makiko、Matsumoto Yuko、Torii Satoru、Honda Shinya、Shimizu Shigeomi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 4 Pages: 107173-107173
- DOI
  10.1016/j.jbc.2024.107173
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07345, KAKENHI-PUBLICLY-23H04773, KAKENHI-PUBLICLY-24H01887, KAKENHI-PROJECT-23K05748
[Journal Article] <i>BCR::ABL1</i>‐induced mitochondrial morphological alterations as a potential clinical biomarker in chronic myeloid leukemia2024
- Author(s)
  Suzuki Kohjin、Watanabe Naoki、Torii Satoru、Arakawa Satoko、Ochi Kiyosumi、Tsuchiya Shun、Yamada Kazuhiro、Kawamura Yoko、Ota Sadao、Komatsu Norio、Shimizu Shigeomi、Ando Miki、Takaku Tomoiku
- Journal Title
  
  Cancer Science
  
  Volume: 116 Issue: 3 Pages: 673-689
- DOI
  10.1111/cas.16424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04773, KAKENHI-PUBLICLY-24H01887, KAKENHI-PROJECT-24K02052, KAKENHI-PROJECT-23K05748
[Journal Article] Subcellular localization and ER-mediated cytotoxic function of α1A and α1ACT in spinocerebellar ataxia type 62024
- Author(s)
  Wang Di、Honda Shinya、Shin Min Kyoung、Watase Kei、Mizusawa Hidehiro、Ishikawa Kinya、Shimizu Shigeomi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 695 Pages: 149481-149481
- DOI
  10.1016/j.bbrc.2024.149481
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07345, KAKENHI-PROJECT-23K06960, KAKENHI-PROJECT-21K07432, KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480, KAKENHI-PROJECT-22H04923
[Journal Article] Modeling of Retina and Optic Nerve Ischemia-Reperfusion Injury through Hypoxia-Reoxygenation in Human Induced Pluripotent Stem Cell-Derived Retinal Ganglion Cells.2024
- Author(s)
  Yoshida T, Yokoi T, Tanaka T, Matsuzaka E, Saida Y, Nishina S, Takada S, Shimizu S, Azuma N
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 2 Pages: 130-130
- DOI
  10.3390/cells13020130
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19606, KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480, KAKENHI-PROJECT-22K09848
[Journal Article] Presence of Gut Microbiota Worsens D‐Galactosamine and Lipopolysaccharide‐Induced Hepatic Injury in Mice2024
- Author(s)
  Ohshima Kazuma、Torii Satoru、Shimizu Shigeomi
- Journal Title
  
  Genes to Cells
  
  Volume: 30 Issue: 1 Pages: 1-12
- DOI
  10.1111/gtc.13183
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23H04773, KAKENHI-PUBLICLY-24H01887, KAKENHI-PROJECT-23K05748
[Journal Article] Photo-protective role of ATG5/ATG7-independent alternative autophagy in human keratinocytes2024
- Author(s)
  Hasegawa Tatsuya、Nakashima Masaya、Torii Satoru、Honda Shinya、Shimizu Shigeomi
- Journal Title
  
  Autophagy Reports
  
  Volume: 3 Issue: 1 Pages: 2396212-2396212
- DOI
  10.1080/27694127.2024.2396212
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23H04773, KAKENHI-PUBLICLY-24H01887
[Journal Article] Identification of small compounds that inhibit multiple myeloma proliferation by targeting c-Maf transcriptional activity2023
- Author(s)
  Asano Kenichi、Kikuchi Kenta、Takehara Miki、Ogasawara Manami、Yoshioka Yuki、Ohnishi Kie、Iwata Ayaka、Shimizu Shigeomi、Tanaka Masato
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 684 Pages: 149135-149135
- DOI
  10.1016/j.bbrc.2023.149135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480
[Journal Article] Biogenesis of fibrils requires <i>C</i>‐mannosylation of <scp>PMEL</scp>2023
- Author(s)
  Kawahara Ryota、Usami Tomoko、Arakawa Satoko、Kamo Hiroki、Suzuki Takehiro、Komatsu Ryosuke、Hara Hiroyuki、Niwa Yuki、Shimizu Erina、Dohmae Naoshi、Shimizu Shigeomi、Simizu Siro
- Journal Title
  
  The FEBS Journal
  
  Volume: 290 Issue: 22 Pages: 5373-5394
- DOI
  10.1111/febs.16927
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480
[Journal Article] Development of small fluorescent probes for the analysis of autophagy kinetics2023
- Author(s)
  Sakurai Hajime Tajima、Iwashita Hidefumi、Arakawa Satoko、Yikelamu Alifu、Kusaba Mizuki、Kofuji Satoshi、Nishina Hiroshi、Ishiyama Munetaka、Ueno Yuichiro、Shimizu Shigeomi
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 7 Pages: 107218-107218
- DOI
  10.1016/j.isci.2023.107218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H04639, KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480
[Journal Article] Uncovering the Localization and Function of a Novel Read-Through Transcript ‘TOMM40-APOE’2023
- Author(s)
  Chang Shichen、Torii Satoru、Inamo Jun、Ishikawa Kinya、Kochi Yuta、Shimizu Shigeomi
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 1 Pages: 69-69
- DOI
  10.3390/cells13010069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05748, KAKENHI-PROJECT-23K23860, KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480
[Journal Article] Involvement of casein kinase 1 epsilon/delta (Csnk1e/d) in the pathogenesis of familial Parkinson's disease caused by <scp>CHCHD2</scp>2023
- Author(s)
  Torii Satoru、Arakawa Satoko、Sato Shigeto、Ishikawa Kei‐ichi、Taniguchi Daisuke、Sakurai Hajime Tajima、Honda Shinya、Hiraoka Yuuichi、Ono Masaya、Akamatsu Wado、Hattori Nobutaka、Shimizu Shigeomi
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: 15 Issue: 9
- DOI
  10.15252/emmm.202317451
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05748, KAKENHI-PUBLICLY-22H04639, KAKENHI-PROJECT-21H02814, KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480
[Journal Article] Lactiplantibacillus plantarum OLL2712 Induces Autophagy via MYD88 and Strengthens Tight Junction Integrity to Promote the Barrier Function in Intestinal Epithelial Cells2023
- Author(s)
  Watanabe-Yasuoka Yumiko、Gotou Ayako、Shimizu Shigeomi、Sashihara Toshihiro
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 12 Pages: 2655-2655
- DOI
  10.3390/nu15122655
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H04639, KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480
[Journal Article] Absence of ULK1 decreases AMPK activity in the kidney, leading to chronic kidney disease progression2023
- Author(s)
  Tomoki Yanagi, Hiroaki Kikuchi, Koichiro Susa, Naohiro Takahashi, Naohiro Takahashi, Hiroki Bamba, Takefumi Suzuki, Yuta Nakano, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Shintaro Mandai, Takayasu Mori, Koh Takeuchi, Shinya Honda, Satoru Torii, Shigeomi Shimizu, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 1 Pages: 5-14
- DOI
  10.1111/gtc.12989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08223, KAKENHI-PROJECT-21K08249, KAKENHI-PROJECT-22K07345, KAKENHI-PROJECT-22K19518, KAKENHI-PROJECT-20H00467, KAKENHI-PROJECT-21K20710, KAKENHI-WRAPUP-22H04899, KAKENHI-PROJECT-23K19610, KAKENHI-PUBLICLY-22H04639, KAKENHI-PROJECT-20H03378
[Journal Article] Beclin1 is essential for the pancreas development2023
- Author(s)
  Mehanna Sally、Arakawa Satoko、Imasaka Mai、Chen Wenting、Nakanishi Yuto、Nishiura Hiroshi、Shimizu Shigeomi、Ohmuraya Masaki
- Journal Title
  
  Developmental Biology
  
  Volume: 504 Pages: 113-119
- DOI
  10.1016/j.ydbio.2023.09.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20666, KAKENHI-PROJECT-22K07997, KAKENHI-PUBLICLY-22H04639, KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480
[Journal Article] Identification of a novel type of focal adhesion remodelling via FAK/FRNK replacement, and its contribution to cancer progression2023
- Author(s)
  Tsujioka M, Miyazawa K, Ohmuraya M, Nibe Y, Shirokawa T, Hayasaka H, Mizushima T, Fukuma T, Shimizu S
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 4 Pages: 256-256
- DOI
  10.1038/s41419-023-05774-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07564, KAKENHI-PROJECT-22K07997, KAKENHI-PROJECT-23K06670, KAKENHI-PROJECT-22K14603, KAKENHI-PUBLICLY-22H04639, KAKENHI-PUBLICLY-23H04773, KAKENHI-PROJECT-23H05480
[Journal Article] Role of the orphan transporter SLC35E1 in the nuclear egress of herpes simplex virus 12022
- Author(s)
  Fumio Maeda, Akihisa Kato, Kosuke Takeshima, Misato Shibazaki, Ryota Sato, Takuma Shibata, Kensuke Miyake, Hiroko Kozuka-Hata, Masaaki Oyama, Eigo Shimizu, Seiya Imoto, Satoru Miyano, Shungo Adachi, Tohru Natsume, Koh Takeuchi, Yuhei Maruzuru, Naoto Koyanagi, Jun Arii, Yasushi Kawaguchi
- Journal Title
  
  Journal of Virology
  
  Volume: - Issue: 10 Pages: 10-10
- DOI
  10.1128/jvi.00306-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22524, KAKENHI-PROJECT-20K07511, KAKENHI-PROJECT-21K19370, KAKENHI-PROJECT-21K19498, KAKENHI-PROJECT-22K15468, KAKENHI-PLANNED-21H05280, KAKENHI-PLANNED-22H05184, KAKENHI-PUBLICLY-22H05584, KAKENHI-PROJECT-21H04800, KAKENHI-PROJECT-20H03496, KAKENHI-PROJECT-21K15464, KAKENHI-PROJECT-20H05692, KAKENHI-PROJECT-20H03492, KAKENHI-PUBLICLY-21H00338, KAKENHI-PUBLICLY-21H00417, KAKENHI-WRAPUP-22H04899, KAKENHI-PROJECT-20H03378, KAKENHI-PROJECT-22K19424
[Journal Article] Nickel particles are present in Crohn's disease tissue and exacerbate intestinal inflammation in IBD susceptible mice.2022
- Author(s)
  Hiroki Matsuda, Yoichi Nibe-Shirakihara, Akiko Tamura, Emi Aonuma, Satoko Arakawa, Kana Otsubo, Yasuhiro Nemoto, Takashi Nagaishi, Kiichiro Tsuchiya, Shigeomi Shimizu, Averil Ma, Mamoru Watanabe, Motohiro Uo, Ryuichi Okamoto, Shigeru Oshima.
- Journal Title
  
  Biochemical and Biophysical Research Communications.
  
  Volume: 592 Pages: 74-80
- DOI
  10.1016/j.bbrc.2021.12.111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-20H00467, KAKENHI-PLANNED-17H06414, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-21H02897, KAKENHI-PROJECT-21H02898, KAKENHI-PROJECT-20K08304, KAKENHI-PUBLICLY-21H05743, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20K07353, KAKENHI-PROJECT-21K15968, KAKENHI-WRAPUP-22H04899, KAKENHI-PUBLICLY-22H04639
[Journal Article] FLIP-based autophagy-detecting technique reveals closed autophagic compartments2022
- Author(s)
  Sakurai Hajime Tajima、Arakawa Satoko、Noguchi Saori、Shimizu Shigeomi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 22452-22452
- DOI
  10.1038/s41598-022-26430-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H05743, KAKENHI-PROJECT-20H00467, KAKENHI-PROJECT-20K07353, KAKENHI-PROJECT-21K15082, KAKENHI-WRAPUP-22H04899, KAKENHI-PUBLICLY-22H04639
[Journal Article] Molecular mechanisms and biological roles of GOMED2021
- Author(s)
  Noguchi Saori、Shimizu Shigeomi
- Journal Title
  
  The FEBS Journal
  
  Volume: - Issue: 22 Pages: 7213-7220
- DOI
  10.1111/febs.16281
- Data Source
  KAKENHI-PLANNED-17H06414
[Journal Article] Oxidized Phospholipids and Neutrophil Elastase Coordinately Play Critical Roles in NET Formation2021
- Author(s)
  Tokuhiro Takuto、Ishikawa Akane、Sato Haruka、Takita Shunya、Yoshikawa Ayuri、Anzai Ryoko、Sato Shinichi、Aoyagi Ryohei、Arita Makoto、Shibuya Takumi、Aratani Yasuaki、Shimizu Shigeomi、Tanaka Masato、Yotsumoto Satoshi
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 718586-718586
- DOI
  10.3389/fcell.2021.718586
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-WRAPUP-20H05613, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-21H05029, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20K06446, KAKENHI-PROJECT-21K19387, KAKENHI-PROJECT-20H00467, KAKENHI-PROJECT-20H03473, KAKENHI-PROJECT-19K08894
[Journal Article] Cargo sorting zones in the trans-Golgi network visualized by super-resolution confocal live imaging microscopy in plants2021
- Author(s)
  Shimizu Yutaro、Takagi Junpei、Ito Emi、Ito Yoko、Ebine Kazuo、Komatsu Yamato、Goto Yumi、Sato Mayuko、Toyooka Kiminori、Ueda Takashi、Kurokawa Kazuo、Uemura Tomohiro、Nakano Akihiko
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1901-1901
- DOI
  10.1038/s41467-021-22267-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06303, KAKENHI-PROJECT-20K06650, KAKENHI-PLANNED-17H06420, KAKENHI-PROJECT-18H05275, KAKENHI-PROJECT-18H02470, KAKENHI-ORGANIZER-19H05670, KAKENHI-PLANNED-19H05675, KAKENHI-ORGANIZER-17H06413
[Journal Article] Homeostatic p62 levels and inclusion body formation in CHCHD2 knockout mice2021
- Author(s)
  Sato Shigeto、Noda Sachiko、Torii Satoru、Amo Taku、Ikeda Aya、Funayama Manabu、Yamaguchi Junji、Fukuda Takahiro、Kondo Hiromi、Tada Norihiro、Arakawa Satoko、Watanabe Masahiko、Uchiyama Yasuo、Shimizu Shigeomi、Hattori Nobutaka
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 30 Issue: 6 Pages: 443-453
- DOI
  10.1093/hmg/ddab057
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07878, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-17K09769, KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-20K22744, KAKENHI-PLANNED-17H06414, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-20K07353, KAKENHI-PROJECT-21K15198, KAKENHI-PROJECT-20H00467
[Journal Article] Molecular mechanisms and biological roles of GOMED.2021
- Author(s)
  Noguchi S, Shimizu S
- Journal Title
  
  FEBS J
  
  Volume: 17 Issue: 16 Pages: 1-7
- DOI
  10.1111/febs.16473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00467
[Journal Article] Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy2020
- Author(s)
  Torii Satoru、Yamaguchi Hirofumi、Nakanishi Akira、Arakawa Satoko、Honda Shinya、Moriwaki Kenta、Nakano Hiroyasu、Shimizu Shigeomi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1754-1754
- DOI
  10.1038/s41467-020-15577-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-19K07382, KAKENHI-PROJECT-19K07399, KAKENHI-PROJECT-20K07353, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-18K06210, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414
[Journal Article] ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.2020
- Author(s)
  Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, Nishitoh H.
- Journal Title
  
  Life science alliance
  
  Volume: 3 Issue: 3 Pages: 201900576-201900576
- DOI
  10.26508/lsa.201900576
- NAID
  120006980545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-18K06222, KAKENHI-PROJECT-19K08843, KAKENHI-PLANNED-15H05931, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-18H04699, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-18H02973, KAKENHI-PROJECT-19H02853, KAKENHI-PROJECT-17K09862, KAKENHI-PROJECT-18K06916, KAKENHI-PROJECT-18K19469, KAKENHI-PROJECT-20K07353, KAKENHI-PROJECT-18H03995, KAKENHI-PUBLICLY-20H05314, KAKENHI-ORGANIZER-17H06413
[Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages.2020
- Author(s)
  Yasueda A, Kayama H, Murohashi M, Nishimura J, Wakame K, Komatsu K, Ogino T, Miyoshi N, Takahashi H, Uemura M, Matsuda C, Kitagawa T, Takeda K, Ito T, Doki Y, Eguchi H, Shimizu S, Mizushima T
- Journal Title
  
  Scientific reports
  
  Volume: press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01533
[Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages2020
- Author(s)
  4.Yasueda A, Kayama H, Murohashi M, Nishimura J, Wakame K, Komatsu K, Ogino T, Miyoshi N, Takahashi H, Uemura M, Matsuda C, Kitagawa T, Takeda K, Ito T, Doki Y, Eguchi H, Shimizu S, Mizushima T
- Journal Title
  
  Scientific Reports
  
  Volume: press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06414
[Journal Article] Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration2020
- Author(s)
  Yamaguchi Hirofumi、Honda Shinya、Torii Satoru、Shimizu Kimiko、Katoh Kaoru、Miyake Koichi、Miyake Noriko、Fujikake Nobuhiro、Sakurai Hajime Tajima、Arakawa Satoko、Shimizu Shigeomi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 5311-5311
- DOI
  10.1038/s41467-020-18892-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07382, KAKENHI-PROJECT-19K08859, KAKENHI-PROJECT-20K07353, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-19K16119, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417
[Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages2020
- Author(s)
  Yasueda Asuka、Kayama Hisako、Murohashi Michiko、Nishimura Junichi、Wakame Koji、Komatsu Ken-ichi、Ogino Takayuki、Miyoshi Norikatsu、Takahashi Hidekazu、Uemura Mamoru、Matsuda Chu、Kitagawa Toru、Takeda Kiyoshi、Ito Toshinori、Doki Yuichiro、Eguchi Hidetoshi、Shimizu Shigeomi、Mizushima Tsunekazu
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-65306-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414
[Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages.2020
- Author(s)
  Yasueda A, Kayama H, Murohashi M, Nishimura J, Wakame K, Komatsu K, Ogino T, Miyoshi N, Takahashi H, Uemura M, Matsuda C, Kitagawa T, Takeda K, Ito T, Doki Y, Eguchi H, Shimizu S, Mizushima T
- Journal Title
  
  Scientific Reports
  
  Volume: press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Journal Article] The Ceramide Analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide Induces Large Lipid Droplet Accumulation and Highlights the Effect of LAMP-2 Deficiency on Lipid Droplet Degradation2020
- Author(s)
  Yuji Kato, Satoko Arakawa, Kazue Terasawa, Jin-Ichi Inokuchi, Takanori Iwata, Shigeomi Shimizu, Tetsuro Watabe, Miki Hara-Yokoyama
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 3 Pages: 126891-126891
- DOI
  10.1016/j.bmcl.2019.126891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K12005, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-20K07353, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-20H03452
[Journal Article] Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface2019
- Author(s)
  Toyoda Y, Morimoto K, Suno R, et al.
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 1 Pages: 18-26
- DOI
  10.1038/s41589-018-0131-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K14904, KAKENHI-PLANNED-15H05905, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01531, KAKENHI-PROJECT-17H03663, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-19K22503, KAKENHI-PROJECT-19K16354, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
[Journal Article] Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming2019
- Author(s)
  Muraoka Naoto、Nara Kaori、Tamura Fumiya、Kojima Hidenori、Yamakawa Hiroyuki、Sadahiro Taketaro、Miyamoto Kazutaka、Isomi Mari、Haginiwa Sho、Tani Hidenori、Kurotsu Shota、Osakabe Rina、Torii Satoru、Shimizu Shigeomi、Okano Hideyuki、Sugimoto Yukihiko、Fukuda Keiichi、Ieda Masaki
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 674-674
- DOI
  10.1038/s41467-019-08626-y
- NAID
  120007128245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-18K08047, KAKENHI-PROJECT-18K08114, KAKENHI-PROJECT-17K16024, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05905, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-17J06637, KAKENHI-PROJECT-18J21479, KAKENHI-PROJECT-15K09147, KAKENHI-PROJECT-16K19426, KAKENHI-PROJECT-19K22503
[Journal Article] Beclin 1 regulates recycling endosome and is required for skin development in mice2019
- Author(s)
  Noguchi Saori、Honda Shinya、Saitoh Tatsuya、Matsumura Hiroyuki、Nishimura Emi、Akira Shizuo、Shimizu Shigeomi
- Journal Title
  
  Communications Biology
  
  Volume: 2 Issue: 1 Pages: 37-37
- DOI
  10.1038/s42003-018-0279-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0229, KAKENHI-PUBLICLY-17H05614, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-17H06415, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17K19514, KAKENHI-PROJECT-17K15613, KAKENHI-PROJECT-18H02637, KAKENHI-PLANNED-26115003, KAKENHI-PROJECT-26221303
[Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages2019
- Author(s)
  Asuka Yasueda, Hisako Kayama, Michiko Murohashi, Junichi Nishimura, Koji Wakame, Ken-ichi Komatsu, Takayuki Ogino, Norikatsu Miyoshi, Hidekazu Takahashi, Mamoru Uemura, Chu Matsuda, Toru Kitagawa, Kiyoshi Takeda, Toshinori Ito, Yuichiro Doki, Hidetoshi Eguchi, Shigeomi Shimizu and Tsunekazu Mizushima,
- Journal Title
  
  Scientific Reports
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10632
[Journal Article] Prediction of intracellular targets of a small compound by analyzing peptides presented on MHC class I2019
- Author(s)
  Sugimoto Yuna、Murohashi Michiko、Arakawa Satoko、Honda Shinya、Shimizu Shigeomi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 508 Issue: 2 Pages: 480-486
- DOI
  10.1016/j.bbrc.2018.11.089
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17K15613
[Journal Article] Characterization of monoclonal antibodies recognizing each extracellular loop domain of occludin2019
- Author(s)
  Shimizu Yoshimi、Shirasago Yoshitaka、Suzuki Takeru、Hata Tomoyuki、Kondoh Masuo、Hanada Kentaro、Yagi Kiyohito、Fukasawa Masayoshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 166 Issue: 4 Pages: 297-308
- DOI
  10.1093/jb/mvz037
- NAID
  40022023629
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417, KAKENHI-PROJECT-18H02856
[Journal Article] Organelle zones in mitochondria2018
- Author(s)
  Shimizu Shigeomi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 165 Issue: 2 Pages: 101-107
- DOI
  10.1093/jb/mvy068
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533
[Journal Article] Association between autophagy and neurodegenerative diseases2018
- Author(s)
  Fujikake N, Shin M, Shimizu S
- Journal Title
  
  Frontiers Neuroscience
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15230
[Journal Article] Biological Roles of Alternative Autophagy2018
- Author(s)
  Shigeomi Shimizu
- Journal Title
  
  Mol. Cells
  
  Volume: 41 Pages: 50-54
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Journal Article] Association Between Autophagy and Neurodegenerative Diseases.2018
- Author(s)
  Nobuhiro Fujikake, Minkyoung Shin, Shigeomi Shimizu*
- Journal Title
  
  Front. Neurosci.
  
  Volume: 12 Pages: 255-255
- DOI
  10.3389/fnins.2018.00255
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15360, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533
[Journal Article] Small fluorescent molecules for monitoring autophagic flux2018
- Author(s)
  Iwashita Hidefumi、Sakurai Hajime Tajima、Nagahora Noriyoshi、Ishiyama Munetaka、Shioji Kosei、Sasamoto Kazumi、Okuma Kentaro、Shimizu Shigeomi、Ueno Yuichiro
- Journal Title
  
  FEBS Letters
  
  Volume: 592 Issue: 4 Pages: 559-567
- DOI
  10.1002/1873-3468.12979
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
[Journal Article] Biological Roles of Alternative Autophagy2018
- Author(s)
  Shigeomi Shimizu
- Journal Title
  
  Mol. Cells
  
  Volume: 41 Pages: 50-54
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414
[Journal Article] Dram1 regulates DNA damage-induced alternative autophagy2018
- Author(s)
  Nagata M, Arakawa S, Yamaguchi H, Torii S, Endo H, Tsujioka M, Honda S, Nishida Y, Konishi A, Shimizu S
- Journal Title
  
  Cell Stress
  
  Volume: 2 Issue: 3 Pages: 55-65
- DOI
  10.15698/cst2018.03.127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08649, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-17K15448, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
[Journal Article] Molecular mechanisms and physiological roles of Atg5/Atg7-independent alternative autophagy2017
- Author(s)
  Arakawa S, Honda S, Yamaguchi H, Shimizu S.
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 93 Issue: 6 Pages: 378-385
- DOI
  10.2183/pjab.93.023
- NAID
  130005696809
- ISSN
  0386-2208, 1349-2896
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15613, KAKENHI-PUBLICLY-17H05691, KAKENHI-PLANNED-26110005
[Journal Article] Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response.2017
- Author(s)
  Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, Takeuchi O, Kawai T, Shimizu S, Matsuura Y, Akira S, Saitoh T
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 114 Issue: 10 Pages: 2681-2686
- DOI
  10.1073/pnas.1621508114
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01380, KAKENHI-PUBLICLY-15H01381, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-16H06234, KAKENHI-PROJECT-26293107, KAKENHI-PROJECT-26713005, KAKENHI-PROJECT-26860453, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-17K19559, KAKENHI-PUBLICLY-17H05691, KAKENHI-PROJECT-17H04066
[Journal Article] Rhodium-catalyzed odorless synthesis of diaryl sulfides from borylarenes and S-aryl thiosulfonates2017
- Author(s)
  Kanemoto Kazuya、Sugimura Yasuyuki、Shimizu Shigeomi、Yoshida Suguru、Hosoya Takamitsu
- Journal Title
  
  Chemical Communications
  
  Volume: 53 Issue: 77 Pages: 10640-10643
- DOI
  10.1039/c7cc05868c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01133, KAKENHI-PROJECT-15H03118, KAKENHI-PROJECT-17H01533
[Journal Article] Intrinsic autophagy is required for the maintenance of intestinal stem cells and for irradiation-induced intestinal regeneration.2017
- Author(s)
  Asano J, Sato T, Ichinose S, Kajita M, Onai N, Shimizu S, Ohteki T.
- Journal Title
  
  Cell reports
  
  Volume: 20 Issue: 5 Pages: 1050-1060
- DOI
  10.1016/j.celrep.2017.07.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05691, KAKENHI-PROJECT-15H04717, KAKENHI-PROJECT-16K19571, KAKENHI-PROJECT-17H01533
[Journal Article] Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation2017
- Author(s)
  Yotsumoto Satoshi、Muroi Yuito、Chiba Tatsuya、Ohmura Rio、Yoneyama Maki、Magarisawa Megumi、Dodo Kosuke、Terayama Naoki、Sodeoka Mikiko、Aoyagi Ryohei、Arita Makoto、Arakawa Satoko、Shimizu Shigeomi、Tanaka Masato
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 16026-16026
- DOI
  10.1038/s41598-017-15668-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05898, KAKENHI-PLANNED-26110004, KAKENHI-PLANNED-26110005, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-15H04648, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-17H01533
[Journal Article] Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice2017
- Author(s)
  Arakawa S, Tsujioka M, Yoshida T, Tajima-Sakurai H, Nishida Y, Matsuoka Y, Yoshino I, Tsujimoto Y, Shimizu S.
- Journal Title
  
  Cell death and differ
  
  Volume: 9 Issue: 9 Pages: 1598-1608
- DOI
  10.1038/cdd.2017.84
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-17H05691, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
[Journal Article] Live Cell Imaging of Mitochondrial Autophagy with a Novel Fluorescent Small Molecule2017
- Author(s)
  Iwashita Hidefumi、Torii Satoru、Nagahora Noriyoshi、Ishiyama Munetaka、Shioji Kosei、Sasamoto Kazumi、Shimizu Shigeomi、Okuma Kentaro
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 12 Issue: 10 Pages: 2546-2551
- DOI
  10.1021/acschembio.7b00647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01533
[Journal Article] Golgi membrane-associated degradation pathway in yeast and mammals2016
- Author(s)
  H. Yamaguchi, S. Arakawa, T. Kanaseki, T. Miyatsuka, Y. Fujitani, H. Watada, Y. Tsujimoto, S. Shimizu
- Journal Title
  
  EMBO J.
  
  Volume: 35 Issue: 18 Pages: 1991-2007
- DOI
  10.15252/embj.201593191
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K14519, KAKENHI-PROJECT-15K18860, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
[Journal Article] Identification of PPM1D as an essential Ulk1 phosphatase for genotoxic stress‐induced autophagy2016
- Author(s)
  S. Torii, T. Yoshida, S. Arakawa, S. Honda, A. Nakanishi, S. Shimizu
- Journal Title
  
  EMBO reports
  
  Volume: 11 Issue: 11 Pages: 1552-1564
- DOI
  10.15252/embr.201642565
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
[Journal Article] Autophagy suppresses cell migration by degrading GEF-H1, a RhoA GEF2016
- Author(s)
  T. Yoshida, M. Tsujioka, S. Honda, S. Shimizu
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 23 Pages: 34420-9
- DOI
  10.18632/oncotarget.8883
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-16K15230
[Journal Article] Autophagy controls centrosome number by degrading Cep63.2016
- Author(s)
  Watanabe Y, Honda S, Konishi A, Satoko Arakawa S, Murohashi M, Yamaguchi H, Torii S, Tanabe M, Tanaka S, Warabi E, Shimizu S.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13508-13508
- DOI
  10.1038/ncomms13508
- NAID
  120007129257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-26430051, KAKENHI-PROJECT-26460485, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
[Journal Article] TRF2 Protein Interacts with Core Histones to Stabilize Chromosome Ends.2016
- Author(s)
  Konishi A, Izumi T, Shimizu S
- Journal Title
  
  J Biol Chem.
  
  Volume: 291(39) Issue: 39 Pages: 20798-810
- DOI
  10.1074/jbc.m116.719021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-16K15230
[Journal Article] In Situ Characterization of Bak Clusters Responsible for Cell Death Using Single Molecule Localization Microscopy2016
- Author(s)
  Y. Nasu, A. Benke, S. Arakawa, G. Yoshida, G. Kawamura, S. Manley, S. Shimizu, T. Ozawa
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 27505-27505
- DOI
  10.1038/srep27505
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15J02898, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K14016, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-16K19103, KAKENHI-PROJECT-26220805
[Journal Article] Identification of a novel compound that inhibits both mitochondria-mediated necrosis and apoptosis.2015
- Author(s)
  S. Arakawa, I. Nakanomyo, Y. Kudo-Sakamoto, H. Akazawa, I. Komuro, S. Shimizu.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 467 Pages: 1006-11
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Journal Article] Direct Thioamination of Arynes via Reaction with Sulfilimines and Migratory N‐Arylation2015
- Author(s)
  Suguru Yoshida, Takahisa Yano, Yoshihiro Misawa, Yasuyuki Sugimura, Kazunobu Igawa, Shigeomi Shimizu, Katsuhiko Tomooka, Takamitsu Hosoya
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 137 Issue: 44 Pages: 14071-14074
- DOI
  10.1021/jacs.5b10557
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26350971, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-15H03118
[Journal Article] A mild and facile synthesis of aryl and alkenyl sulfides via copper-catalyzed deborylthiolation of organoborons with thiosulfonates2015
- Author(s)
  Suguru Yoshida, Yasuyuki Sugimura, Yuki Hazama, Yoshitake Nishiyama, Takahisa Yano, Shigeomi Shimizu, Takamitsu Hosoya
- Journal Title
  
  Chemical Communications
  
  Volume: 51 Issue: 93 Pages: 16613-16616
- DOI
  10.1039/c5cc07463k
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26350971, KAKENHI-PUBLICLY-15H01554, KAKENHI-PROJECT-15H03118
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014
- Author(s)
  S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu,
- Journal Title
  
  Nature Communications
  
  Volume: press
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24121708
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014
- Author(s)
  S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu,
- Journal Title
  
  Nature Communications
  
  Volume: press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2014
- Author(s)
  S. Honda, S. Arakawa, Y. Nishida, H. Yamaguchi, E. Ishii, S. Shimizu.
- Journal Title
  
  Nature communications
  
  Volume: 5 Issue: 1 Pages: 4004-4004
- DOI
  10.1038/ncomms5004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PROJECT-25670139, KAKENHI-PROJECT-26670503
[Journal Article] Autophagic Cell Death and Cancer.2014
- Author(s)
  S. Shimizu, T. Yoshida, M. Tsujioka, S. Arakawa.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 15 Issue: 2 Pages: 3145-3153
- DOI
  10.3390/ijms15023145
- NAID
  40019721683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PROJECT-25670139
[Journal Article] Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes.2014
- Author(s)
  Honda S, Arakawa S, Nishida Y, Yamaguchi H, Ishii E, Shimizu S,
- Journal Title
  
  Nature Commun
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670139
[Journal Article] Alternative Macroautophagy and Mitophagy2014
- Author(s)
  S. Shimizu, S. Honda, S. Arakawa, H. Yamaguchi
- Journal Title
  
  Int. J. Biochem. Cell Biol.
  
  Volume: 50 Pages: 64-66
- DOI
  10.1016/j.biocel.2014.02.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PROJECT-25670139
[Journal Article] Inhibition of epithelial cell death by Bcl-2 improved chronic colitis in IL10 KO mice2013
- Author(s)
  T. Mizushima, S. Arakawa, Y. Sanada, I. Yoshino, D. Miyazaki, H. Urushima, Y. Tsujimoto, T. Ito, S. Shimizu
- Journal Title
  
  Am J Pathol.
  
  Volume: 183 Issue: 6 Pages: 1936-1944
- DOI
  10.1016/j.ajpath.2013.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002, KAKENHI-PUBLICLY-24121708, KAKENHI-PROJECT-24659178, KAKENHI-PROJECT-24689020, KAKENHI-PUBLICLY-25113509, KAKENHI-PUBLICLY-25131710, KAKENHI-PROJECT-25650078, KAKENHI-PROJECT-25670139
[Journal Article] オートファジー細胞死の分子機構とその生体での役割2012
- Author(s)
  清水重臣
- Journal Title
  
  「実験医学」羊土社
  
  Volume: 30 Pages: 550-5
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Involvement of Beclin 1 in the engulfment of apoptotic cells2012
- Author(s)
  A. Konishi, S. Arakawa, Z. Yue, S.Shimizu
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 13919-29
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] 生体におけるマイトファジーの役割2012
- Author(s)
  清水重臣
- Journal Title
  
  「実験医学」羊土社
  
  Volume: 30 Pages: 1390-95
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Shigella targets epithelial tricellular junctions to spread between cells via a noncanonicalclathrin-dependent endocytic pathway2012
- Author(s)
  M. Fukamatsu, M. Ogawa, S. Arakawa, H.Ashida, M. Suzuki, M. Furuse, K. Nakayama, S. Shimizu, M. Kin, H. Mimuro, C. Sasakawa
- Journal Title
  
  Cell Host Microbe
  
  Volume: 11 Pages: 325-336
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Transformation of an antimicrobial peptide into a plasma membrane- permeable,mitochondria-targeted peptide via the substitution of lysine with arginine2012
- Author(s)
  I. Nakase, S. Okumura, S. Katayama, H. Hirose, S. Pujals, H. Yamaguchi, S. Arakawa, S. Shimizu, S. Futaki
- Journal Title
  
  Chemical Communication
  
  Volume: 48 Pages: 11097-99
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Inhibits Vascular Endothelial Growth Factor Expression in Solid Tumor2012
- Author(s)
  Y. Yoshioka, S. Shimizu, T. Ito, M.Taniguchi, M. Nomura, T. Nishida, Y. Sawa.
- Journal Title
  
  J Surg Res
  
  Volume: 174 Pages: 291-297
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Hypertrophy and unconventional cell division of hepatocytes underlie liver regeneration2012
- Author(s)
  Y. Miyaoka, K. Ebato, H. Kato, S. Arakawa, S. Shimizu, A. Miyajima
- Journal Title
  
  Curr. Biol
  
  Volume: 22 Pages: 1166-75
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Stress-activated protein kinase MKK7 regulates axon elongation in thedeveloping cerebral cortex2011
- Author(s)
  T. Yamasaki, H. Kawasaki, S. Arakawa, K. Shimizu, S. Shimizu, O. Reiner, H. Okano, S. Nishina, N. Azuma, J.M. Penninger, T. Katada, H Nishina
- Journal Title
  
  Journal ofNeuroscience
  
  Volume: 31 Pages: 16872-16883
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Spatial coupling of mTOR and autophagy augments secretory/phenotypes2011
- Author(s)
  Masako Narita
- Journal Title
  
  Science
  
  Volume: 332 Issue: 6032 Pages: 966-970
- DOI
  10.1126/science.1205407
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-22770054, KAKENHI-PROJECT-23657084
[Journal Article] Stress-activated protein kinase MKK7 regulates axon elongation in the developing cerebral cortex.2011
- Author(s)
  Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 31 Pages: 16872-16883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fasactivation in Bak/Bax-deficient mice2011
- Author(s)
  Hikita, H.
- Journal Title
  
  Hepatology
  
  Volume: VOL. 54 Issue: 1 Pages: 240-251
- DOI
  10.1002/hep.24305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0316, KAKENHI-PROJECT-21590841, KAKENHI-PROJECT-21659188, KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-23657084
[Journal Article] Spatialcoupling of mTOR and autophagy augments secretory phenotypes2011
- Author(s)
  M. Narita, A.R.J. Young, S. Arakawa, S.A. Samarajiwa, T. Nakashima, S. Yoshida, S.K. Hong, L.S. Berry, S. Reichelt, M. Ferreira, S. Tavare, K. Inoki, S. Shimizu, M. Narita
- Journal Title
  
  Science
  
  Volume: 332 Pages: 966-970
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Journal Title
  
  「臨床血液」教育講演号
- NAID
  10029769484
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] ミトコンドリアの変化2011
- Author(s)
  清水重臣
- Journal Title
  
  「細胞死解析プロトコール」羊土社
  
  Pages: 108-118
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice2011
- Author(s)
  H. Hikita, T. Takehara, T. Kodama, S. Shimizu, M. Shigekawa, A. Hosui, T. Miyagi, T. Tatsumi, H. Ishida, Li W, T. Kanto, N. Hiramatsu, S. Shimizu, Y. Tsujimoto, N. Hayashi
- Journal Title
  
  Hepatology
  
  Volume: 54 Pages: 240-251
- Data Source
  KAKENHI-PROJECT-23657084
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020009
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659076
[Journal Article] Autophagy takes an alternative pathway2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002
[Journal Article] Autophagy takes an alternative pathway2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659076
[Journal Article] Autophagy takes an alternative pathway2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121505
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229002
[Journal Article] Involvement of JNK in the regulation of autophagic cell death.2010
- Author(s)
  S.Shimizu, et al
- Journal Title
  
  Oncogene (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659076
[Journal Article] Autophagy takes an alternative pathway2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Autophagy
  
  Volume: 6 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020009
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  S.Shimizu, et al.
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22121505
[Journal Article] Role of the mitochondrial membrane permeability transition in cell death.2007
- Author(s)
  Tsujimoto Y & Shimizu S
- Journal Title
  
  Apoptosis 5
  
  Pages: 835-840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Furanonaphthoquinones cause apoptosis of cancer cells by inducing the production of reactive oxygen species by the mitochondrial voltage-dependent anion channel.2006
- Author(s)
  Simamura, E., Hirai, K., Shimada, H., Koyama, J., Niwa, Y., Shimizu, S.
- Journal Title
  
  Cancer Biology ＆ Therapy 5
  
  Pages: 11523-11523
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Mitochondrial membrane permeability transition and cell death.2006
- Author(s)
  Tsujimoto, Y., Nakagawa, T., Shimizu, S.
- Journal Title
  
  Biochim Biophys Acta. 9-10
  
  Pages: 1297-1297
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway.2006
- Author(s)
  Ito, K., Oji, Y., Tatsumi, N., Shimizu, S., et al.
- Journal Title
  
  Oncogene 25
  
  Pages: 4217-4217
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Mitochondrial membrane permeability transition and cell death.2006
- Author(s)
  Tsujimoto, Y., Nakagawa, T., Shimizu, S.
- Journal Title
  
  Biochim Biophys Acta. 9-10
  
  Pages: 1297-1297
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Furanonaphthoquinones cause apoptosis of cancer cells by inducing the production of reactive oxygen species by the mitochondrial voltage-dependent anion channel.2006
- Author(s)
  Simamura, E., Hirai, K., Shimada, H., Koyama, J., Niwa, Y., Shimizu, S.
- Journal Title
  
  Cancer Biology ＆ Therapy 5
  
  Pages: 11523-11523
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway.2006
- Author(s)
  Ito, K., Oji, Y., Tatsumi, N, Shimizu, S., et al.
- Journal Title
  
  Oncogene 25
  
  Pages: 4217-4217
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage.2005
- Author(s)
  Chen C, Shimizu S, et al.
- Journal Title
  
  Biochem Biophys Res Commun 333
  
  Pages: 427-431
- Data Source
  KAKENHI-PROJECT-17591331
[Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005
- Author(s)
  T.Nakagawa, S.Shimizu, et al.
- Journal Title
  
  Nature 434
  
  Pages: 652-658
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Two distinct Fas-activated signaling pathways revealed by an antitumor drug D609.2005
- Author(s)
  Zhang L, Shimizu S, et al.
- Journal Title
  
  Oncogene. 24
  
  Pages: 2954-2962
- Data Source
  KAKENHI-PROJECT-17591331
[Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage2005
- Author(s)
  C.Chen, S.Shimizu, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 333
  
  Pages: 427-431
- Data Source
  KAKENHI-PROJECT-17025025
[Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005
- Author(s)
  Nakagawa T, Shimizu S, et al.
- Journal Title
  
  Nature. 434
  
  Pages: 652-658
- Data Source
  KAKENHI-PROJECT-17591331
[Journal Article] Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage2005
- Author(s)
  C.Chen, S.Shimizu, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 333
  
  Pages: 427-431
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.2005
- Author(s)
  T.Nakagawa, S.Shimizu, et al.
- Journal Title
  
  Nature 434
  
  Pages: 652-658
- Data Source
  KAKENHI-PROJECT-17025025
[Journal Article] Another way to die : autophagic programmed cell death.2005
- Author(s)
  Tsujimoto Y, Shimizu S.
- Journal Title
  
  Cell Death Differ 12
  
  Pages: 1528-1534
- Data Source
  KAKENHI-PROJECT-17591331
[Journal Article] Two distinct Fas-activated signaling pathways revealed by an anti-tumor drug D6092005
- Author(s)
  L.Zhang, S.Shimizu, Y.Tsujimoto
- Journal Title
  
  Oncogene 24
  
  Pages: 2954-2962
- Data Source
  KAKENHI-PROJECT-17025025
[Journal Article] Two distinct Fas-activated signaling pathways revealed by an anti-tumor drug D6092005
- Author(s)
  L.Zhang, S.Shimizu.Y.Tsujimoto
- Journal Title
  
  Oncogene 24
  
  Pages: 2954-2962
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] A role of Bcl-2 family of proteins in non-apoptotic programmed cell death dependent on autophagy genes.2004
- Author(s)
  Shimizu, S., et al.
- Journal Title
  
  Nature Cell Biol. 6
  
  Pages: 1221-1228
- Data Source
  KAKENHI-PROJECT-16023240
[Journal Article] Role of the mitochondrial membrane permeability transition in cell death.
- Author(s)
  Tsujimoto, Y., Shimizu, S.
- Journal Title
  
  Apoptosis (印刷中)
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] オートファジーの新たな展開とそれによる炎症制御
- Author(s)
  清水重臣
- Journal Title
  
  細胞工学
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-22247016
[Journal Article] 神経変性疾患とミトコンドリア傷害
- Author(s)
  清水重臣
- Journal Title
  
  神経変性疾患のサイエンス (印刷中)
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] 神経変性疾患とミトコンドリア傷害
- Author(s)
  清水重臣
- Journal Title
  
  神経変性疾患のサイエンス (印刷中)
- Data Source
  KAKENHI-PROJECT-18023024
[Journal Article] Role of the mitochondrial membrane permeability transition in cell death.
- Author(s)
  Tsujimoto, Y., Shimizu, S.
- Journal Title
  
  Apoptosis (印刷中)
- Data Source
  KAKENHI-PROJECT-17390094
[Journal Article] Atg5非依存性オートファジーの形態学と分子生物学
- Author(s)
  清水重臣、荒川聡子、西田友哉
- Journal Title
  
  顕微鏡
  
  Volume: (印刷中)
- NAID
  130007788943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247016
[Patent] ベンゾチオフェン化合物、該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤、並びに抗癌活性を有する化合物をスクリーニングするための方法2013
- Inventor(s)
  清水重臣、室橋道子、細谷孝充、吉田優
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-07
- Overseas
- Data Source
  KAKENHI-PROJECT-22229002
[Patent] ベンゾチオフェン化合物、該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤、並びに抗癌活性を有する化合物をスクリーニングするための方法2013
- Inventor(s)
  Shigeomi SHIMIZU, Takamitsu HOSOYA, Michiko MUROHASHI, Suguru YOSHIDA
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2013-02-07
- Overseas
- Data Source
  KAKENHI-PROJECT-23657084
[Patent] ベンゾチオフェン化合物、該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤、並びに抗癌活性を有する化合物をスクリーニングするための方法2013
- Inventor(s)
  清水重臣、室橋道子、細谷孝充、吉田優
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-07
- Overseas
- Data Source
  KAKENHI-PUBLICLY-24121708
[Patent] ベンゾチオフェン化合物、該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤、並びに抗癌活性を有する化合物をスクリーニングするための方法2013
- Inventor(s)
  清水重臣、室橋道子、細谷孝充、吉田優
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-07
- Overseas
- Data Source
  KAKENHI-PROJECT-23657084
[Patent] 抗癌活性を有する化合物をスクリーニングするための方法2012
- Inventor(s)
  清水重臣、室橋道子
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2012-026377
- Filing Date
  2012-02-09
- Data Source
  KAKENHI-PROJECT-23657084
[Patent] ベンゾチオフェン化合物、並びに該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤2012
- Inventor(s)
  清水重臣室橋道子細谷孝充吉田満
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2012-026373
- Filing Date
  2012
- Data Source
  KAKENHI-PROJECT-23657084
[Patent] ベンゾチオフェン化合物、並びに該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤2012
- Inventor(s)
  清水重臣、細谷孝充、室橋道子、吉田優
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学出願
- Industrial Property Number
  2012-026373
- Filing Date
  2012-02-09
- Data Source
  KAKENHI-PROJECT-23657084
[Patent] 抗癌活性を有する化合物をスクリーニングするための方法2012
- Inventor(s)
  清水重臣室橋道子
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2012-026377
- Filing Date
  2012
- Data Source
  KAKENHI-PROJECT-23657084
[Patent] 抗癌活性を有する化合物をスクリーニングするための方法2012
- Inventor(s)
  清水重臣, 室橋道子
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2012-026377
- Filing Date
  2012-02-09
- Data Source
  KAKENHI-PROJECT-22229002
[Patent] ベンゾチオフェン化合物、並びに該化合物を有効成分とするオルタナティブオートファジー誘導剤及び抗癌剤2012
- Inventor(s)
  清水重臣, 室橋道子, 細谷孝充, 吉田満
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Industrial Property Number
  2012-026373
- Filing Date
  2012-02-09
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Autophagy regulates centrosome number by degrade cytosolic Cep63 and inhibits tumorigenesis2025
- Author(s)
  本田真也、清水重臣
- Organizer
  第４回Cell Deathコロキアム
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04773
[Presentation] Autophagy regulates centrosome number by degrade cytosolic Cep63 and inhibits tumorigenesis2025
- Author(s)
  本田真也、清水重臣
- Organizer
  第４回Cell Deathコロキアム
- Invited
- Data Source
  KAKENHI-PUBLICLY-24H01887
[Presentation] ゴルジ体におけるタンパク質分解機構GOMEDの解析2024
- Author(s)
  清水重臣
- Organizer
  第76回細胞生物学会
- Data Source
  KAKENHI-PUBLICLY-24H01887
[Presentation] ゴルジ体におけるタンパク質分解機構GOMEDの解析2024
- Author(s)
  清水重臣
- Organizer
  第76回細胞生物学会
- Data Source
  KAKENHI-PUBLICLY-23H04773
[Presentation] Biological roles of GOMED2023
- Author(s)
  Shigeomi Shimizu
- Organizer
  Organellar Zone International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-22H04899
[Presentation] Biological roles of GOMED2023
- Author(s)
  Shigeomi Shimizu
- Organizer
  Organellar Zone International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00467
[Presentation] Biological roles of GOMED2022
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 10th International Synposium on Autophagy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00467
[Presentation] 新規オートファジー GOMED とケミカルバイオロジー2022
- Author(s)
  清水重臣
- Organizer
  第142回日本薬学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] Insulin Degradation via Noncanonical Autophagy, GOMED2022
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 7th Diabetes Research Innovation Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00467
[Presentation] 新規オートファジー GOMED とケミカルバイオロジー2022
- Author(s)
  清水重臣
- Organizer
  第142回日本薬学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00467
[Presentation] ホスホイノシチドが制御する新たなタンパク質分解系GOMEDの生理機能とその破綻による多彩な疾患2021
- Author(s)
  清水重臣
- Organizer
  第１８２回東京脂質談話会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00467
[Presentation] Molecular mechanisms and physiological roles of Atg5-independent mitophagy2021
- Author(s)
  Shigeomi Shimizu
- Organizer
  ASMRM
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] オルタナティブ・オートファジーと神経変性疾患2021
- Author(s)
  清水重臣
- Organizer
  第40回日本認知症学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] ゴルジ体ストレス時に見られるゴルジ体調節機構2021
- Author(s)
  清水重臣
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H00467
[Presentation] ゴルジ体ストレス時に見られるゴルジ体調節機構2021
- Author(s)
  清水重臣
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] New insights into the mechanism of Golgi-mediated alternative autophagy using chemical biology approach2021
- Author(s)
  Shigeomi Shimizu
- Organizer
  ゲーテ大学CRC seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] Molecular mechanism and biological roles of Atg5-independent alternative autophagy2021
- Author(s)
  Shigeomi Shimizu
- Organizer
  ゲーテ大学CRC seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00467
[Presentation] オルタナティブ・オートファジーと神経変性疾患2021
- Author(s)
  清水重臣
- Organizer
  第40回日本認知症学会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00467
[Presentation] ２種類のオートファジーによるミトコンドリアqualityの調節2020
- Author(s)
  清水重臣
- Organizer
  AMED村山班　TR会議
- Invited
- Data Source
  KAKENHI-PROJECT-17H01533
[Presentation] 細胞死、ミトコンドリアと臓器不全2020
- Author(s)
  清水重臣
- Organizer
  第47回　日本集中治療医学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01533
[Presentation] 新規オートファジーによるインスリン分解機構2020
- Author(s)
  清水重臣
- Organizer
  7th Diabetes Research Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-17H01533
[Presentation] Molecular mechanisms and physiological roles of alternative autophagy2019
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Data Source
  KAKENHI-PROJECT-17H01533
[Presentation] New insights into the mechanism of Golgi-mediated alternative autophagy using chemical biology approach2019
- Author(s)
  Shigeomi Shimizu
- Organizer
  International Symposium of Autophagy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] Molecular mechanisms and physiological roles of alternative autophagy2019
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 92nd Annual Meeting of the Japanese Biochemical Society
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] Molecular mechanisms and physiological roles of Atg5-independent mitophagy2019
- Author(s)
  Shigeomi Shimizu
- Organizer
  ASMRM & J-mit
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] Molecular mechanisms and physiological roles of Atg5-independent mitophagy2019
- Author(s)
  Shigeomi Shimizu
- Organizer
  ASMRM & J-mit
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01533
[Presentation] Atg5非依存的オートファジーの分子機構と生理機2019
- Author(s)
  清水重臣
- Organizer
  第12回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-17H01533
[Presentation] Autophagy induction of epithelium alleviate colitis in DSS model mice2019
- Author(s)
  Asuka Yasueda, Shigeomi Shimizu, Junichi Nishimura, Michiko Murohashi, Takayuki Ogino, Yoshifumi Watanabe, Koji Wakame, Kenichi Komatsu, Norikatsu Miyoshi, Hidekazu Takahashi ,Mamoru Uemura, Chu Matsuda, Tsunekazu Mizushima, Masaki Mori, Yuichiro Doki,
- Organizer
  UEG WEEK 2019 Bercelona (Spain)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10632
[Presentation] 細胞死とオートファジーのクロストーク2019
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Data Source
  KAKENHI-PROJECT-17H01533
[Presentation] オートファジー誘導物質による薬剤誘導性腸炎緩和効果の検討2019
- Author(s)
  安枝明日香, 荻野崇之, 清水重臣, 西村潤一, 室橋道子, 渡部嘉文, 三吉範克,高橋秀和, 原口直紹, 畑泰司, 松田宙, 水島恒和, 森正樹, 土岐祐一郎
- Organizer
  第56回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-17K10632
[Presentation] New insights into the mechanism of Golgi-mediated alternative autophagy using chemical biology approach2019
- Author(s)
  Shigeomi Shimizu
- Organizer
  International Symposium of Autophagy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] New insights into the mechanism of Golgi-mediated alternative autophagy using chemical biology approach2019
- Author(s)
  Shigeomi Shimizu
- Organizer
  International Symposium of Autophagy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01533
[Presentation] Molecular mechanisms and physiological roles of Atg5-independent mitophagy2019
- Author(s)
  Shigeomi Shimizu
- Organizer
  ASMRM & J-mit
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] オートファジーと疾患2018
- Author(s)
  清水重臣
- Organizer
  第6回AAA会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] オートファジーと疾患2018
- Author(s)
  清水重臣
- Organizer
  第6回AAA会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] 新規オートファジーの分子機構とその破綻による疾患2017
- Author(s)
  清水重臣
- Organizer
  第22回日本病態プロテアーゼ学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017
- Author(s)
  清水重臣
- Organizer
  第76回日本癌学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] 新規オートファジーの分子機構とその破綻による疾患2017
- Author(s)
  清水重臣
- Organizer
  第22回日本病態プロテアーゼ学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] 新規オートファジーの分子機構とその破綻による疾患2017
- Author(s)
  清水重臣
- Organizer
  第22回日本病態プロテアーゼ学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] オートファジーが関わる細胞死2017
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017
- Author(s)
  清水重臣
- Organizer
  第76回日本癌学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] オートファジーが関わる細胞死2017
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06413
[Presentation] オートファジーが関わる細胞死2017
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06414
[Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017
- Author(s)
  清水重臣
- Organizer
  第76回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Mitophagy and alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine
- Place of Presentation
  TKP Garden City Shinagawa, Shinagawa
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Mitophagy and alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine
- Place of Presentation
  TKP Garden City Shinagawa, Shinagawa
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Identification of natural product against fatty liver disease based on the induction of alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  ICNIM2016
- Place of Presentation
  Hotel Royton, Sapporo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2016
- Author(s)
  清水重臣
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜, 横浜
- Invited
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Alternative Autophagy is Essential for Neuronal Cell Maintenance2016
- Author(s)
  Shimizu S
- Organizer
  Brain Protein Aging and Dementia Control International Workshop
- Place of Presentation
  Kakuyu Kaikan in Nagoya University, Nagoya
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15230
[Presentation] Molecular mechanisms of Atg5-independent alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  Gordon Research Conference.
- Place of Presentation
  ロスアンジェルス（米国）
- Year and Date
  2016-03-20
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Alternative Autophagy is Essential for Neuronal Cell Maintenance2016
- Author(s)
  Shimizu S
- Organizer
  Brain Protein Aging and Dementia Control International Workshop
- Place of Presentation
  Kakuyu Kaikan in Nagoya University, Nagoya
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Identification of natural product against fatty liver disease based on the induction of alternative autophagy2016
- Author(s)
  Shimizu S
- Organizer
  ICNIM2016
- Place of Presentation
  Hotel Royton, Sapporo
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Macroautophagy mediates elimination of mitochondria from embryonic reticulocytes2016
- Author(s)
  清水重臣
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜、横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Development of Small Compound against Polyglutamine Diseases based on the Regulation of Alternative Autophagy2015
- Author(s)
  Shimizu S
- Organizer
  Brain Protein Aging and Dementia Control　1st InternationalSymposium
- Place of Presentation
  野依記念学術交流館（愛知県・名古屋市）
- Year and Date
  2015-10-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] Biological Roles of Autophagic Cell Death2015
- Author(s)
  Shimizu S
- Organizer
  Japan Australia Meeting on Cell Death
- Place of Presentation
  メルボルン（オーストラリア）
- Year and Date
  2015-10-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01554
[Presentation] 新しく発見したオートファジー機構とオルガネラ分解2014
- Author(s)
  清水重臣
- Organizer
  第５７回日本神経化学会大会
- Place of Presentation
  奈良市
- Year and Date
  2014-09-29
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] 新しく発見したオートファジーと肝疾患2014
- Author(s)
  清水重臣
- Organizer
  第21回　肝細胞研究会
- Place of Presentation
  文京区
- Year and Date
  2014-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] 新しく発見したオートファジー機構とオルガネラ分解2014
- Author(s)
  清水重臣
- Organizer
  第５７回日本神経化学会大会
- Place of Presentation
  奈良市
- Year and Date
  2014-09-29
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] オートファジー破綻に起因する発癌機構の解明とその抗癌剤開発への応用2014
- Author(s)
  清水重臣
- Organizer
  第13回南大阪癌フォーラム
- Place of Presentation
  堺市
- Year and Date
  2014-04-19
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] オートファジー破綻に起因する発癌機構の解明とその抗癌剤開発への応用2014
- Author(s)
  清水重臣
- Organizer
  第13回南大阪癌フォーラム
- Place of Presentation
  堺市
- Year and Date
  2014-04-19
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] 新しく発見したオートファジーと肝疾患2014
- Author(s)
  清水重臣
- Organizer
  第21回　肝細胞研究会
- Place of Presentation
  文京区
- Year and Date
  2014-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013
- Author(s)
  Shimizu S
- Organizer
  International Symposium on Mitochondria
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013
- Author(s)
  Shimizu S
- Organizer
  International Symposium on Mitochondria
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] オートファジーと細胞死のクロストーク2013
- Author(s)
  清水重臣
- Organizer
  第22回日本Cell Death学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Biological Roles of Autophagic Cell Death” CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death2013
- Author(s)
  Shimizu S
- Organizer
  CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
- Place of Presentation
  Suzhou, China
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Biological roles of Autophagic cell death2013
- Author(s)
  Shimizu S
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] オートファジーと細胞死のクロストーク2013
- Author(s)
  清水重臣
- Organizer
  第22回日本Cell Death学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Mitophagy is regulated by Ulk1-dependent alternative macroautophagy during erythrocyte maturation2013
- Author(s)
  Shimizu S
- Organizer
  International Symposium on Mitochondria
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Biological Roles of Autophagic Cell Death2013
- Author(s)
  Shimizu S
- Organizer
  CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
- Place of Presentation
  Suzhou, China
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] オートファジーと細胞死のクロストーク2013
- Author(s)
  清水重臣
- Organizer
  第22回日本Cell Death学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] Biological Roles of Autophagic Cell Death2013
- Author(s)
  Shimizu S
- Organizer
  CSH Asia conference on Mechanisms and Functions of Non-apoptotic Cell Death
- Place of Presentation
  Suzhou, China
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Biological Roles of Autophagic Cell Death2013
- Author(s)
  Shimizu S
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 6th Symposium on Autophagy
- Place of Presentation
  名護市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 様々なストレスに対応する為に機能するオートファジー2012
- Author(s)
  清水重臣
- Organizer
  第16回日本統合医療学会
- Place of Presentation
  豊中市
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Alternative Macroautophagy and Cancer2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012
- Author(s)
  清水重臣
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] なぜ赤血球にはミトコンドリアがないのか?～オートファジーの働き2012
- Author(s)
  清水重臣
- Organizer
  第3回ミトコンドリアとDDS
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Alternative Macroautophagy and Cancer2012
- Author(s)
  清水重臣
- Organizer
  第71回日本癌学会
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Molecular Mechanisms andPhysiological Roles of Atg5/Atg7- independent Macroautophagy2012
- Author(s)
  Shimizu S
- Organizer
  The 6th Symposium on Autophagy
- Year and Date
  2012-10-30
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 放射線によって誘導される様々な細胞死とオートファジー2012
- Author(s)
  清水重臣
- Organizer
  第2回分子状水素医学シンポジウム
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012
- Author(s)
  清水重臣
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 6th Symposium on Autophagy
- Place of Presentation
  名護市
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Alternative Macroautophagy and Cancer2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Molecular Mechanisms and Physiological Roles of Atg5/Atg7-independent Macroautophagy2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  The 6th Symposium on Autophagy
- Place of Presentation
  名護市
- Year and Date
  2012-10-28
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] 様々なストレスに対応する為に機能するオートファジー2012
- Author(s)
  清水重臣
- Organizer
  第16回日本統合医療学
- Place of Presentation
  豊中市
- Year and Date
  2012-12-08
- Invited
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] Maintenance of tissue homeostasis by dying cells and autophagy2012
- Author(s)
  清水重臣
- Organizer
  第35回日本分子生物学会
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Alternative Macroautophagy and Cancer2012
- Author(s)
  Shigeomi Shimizu
- Organizer
  第71回日本癌学会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PUBLICLY-24121708
[Presentation] 様々なストレスに対応する為に機能するオートファジー2012
- Author(s)
  清水重臣
- Organizer
  第16回日本統合医療学会
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋市(招待講演)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011
- Author(s)
  清水重臣
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] 細胞死とオートファジーのクロストーク2011
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Place of Presentation
  文京区
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] 細胞死とオートファジーのクロストーク2011
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Place of Presentation
  文京区
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] オートファジーと神経変性疾患2011
- Author(s)
  清水重臣
- Organizer
  「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
- Place of Presentation
  千代田区(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」(招待講演)
- Place of Presentation
  豊中市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 生体で見られる様々な細胞死とオートファジー2011
- Author(s)
  清水重臣
- Organizer
  第1回横断的腫瘍フォーラム
- Place of Presentation
  吹田市(招待講演)
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] Alternative macroautophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  Parkinson Disease and Mitophagy
- Place of Presentation
  文京区
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] Alternativemacroautophagy International Symposium2011
- Author(s)
  Shimizu S.
- Organizer
  Parkinson Disease and Mitophagy
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーと神経変性疾患2011
- Author(s)
  清水重臣
- Organizer
  「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ(招待講演)
- Place of Presentation
  千代田区
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 生体で見られる様々な細胞死とオートファジー2011
- Author(s)
  清水重臣
- Organizer
  第1回横断的腫瘍フォーラム
- Place of Presentation
  吹田市(招待講演)
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋市(招待講演)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011
- Author(s)
  清水重臣
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] オートファジーと神経変性疾患2011
- Author(s)
  清水重臣
- Organizer
  「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
- Place of Presentation
  千代田区(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会
- Place of Presentation
  名古屋市(招待講演)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Various Types of Cell Death and Autophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] 細胞死を司るミトコンドリア孔の解析2011
- Author(s)
  清水重臣
- Organizer
  過渡的複合体シンポジウム
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Alternative macroautophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  Parkinson Disease and Mitophagy
- Place of Presentation
  文京区
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーと神経変性疾患病態に根ざしたALSの新規治療法開発班2011
- Author(s)
  清水重臣
- Organizer
  平成23年度ワークショップ
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」第7回
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Alternative macroautophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  Parkinson Disease and Mitophagy
- Place of Presentation
  文京区
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」
- Place of Presentation
  豊中市(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] 細胞死とオートファジーのクロストーク2011
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」
- Place of Presentation
  豊中市(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] 細胞死とオートファジーのクロストーク2011
- Author(s)
  清水重臣
- Organizer
  日本Cell Death学会
- Place of Presentation
  文京区
- Year and Date
  2011-07-29
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011
- Author(s)
  清水重臣
- Organizer
  第84回日本生化学会
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーと神経変性疾患2011
- Author(s)
  清水重臣
- Organizer
  「病態に根ざしたALSの新規治療法開発班」平成23年度ワークショップ
- Place of Presentation
  千代田区(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] 生体で見られる様々な細胞死とオートファジー2011
- Author(s)
  清水重臣
- Organizer
  第1回横断的腫瘍フォーラム
- Place of Presentation
  吹田市(招待講演)
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  新適塾「難病への挑戦」
- Place of Presentation
  豊中市(招待講演)
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] 様々な疾患を惹起するミトコンドリア細胞死孔の解析2011
- Author(s)
  清水重臣
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Various Types of Cell Death and Autophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Alternative macroautophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  Parkinson Disease and Mitophagy
- Place of Presentation
  文京区
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Various Types of Cell Death and Autophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] オートファジーを標的とした難治疾患克服への戦略2011
- Author(s)
  清水重臣
- Organizer
  金沢大学がん進展制御研究所セミナー
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] Various Types of Cell Death and Autophagy2011
- Author(s)
  Shigeomi Shimizu
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] アポトーシスと非アポトーシス細胞死2011
- Author(s)
  清水重臣
- Organizer
  第73回日本血液学会(招待講演)
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] 生体で見られる様々な細胞死とオートファジー2011
- Author(s)
  清水重臣
- Organizer
  第1回横断的腫瘍フォーラム
- Year and Date
  2011-12-07
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] A critical role for the autophagy gene Ulkl in Atg5- independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  Gordon Conference
- Place of Presentation
  Italy
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] A critical role for the autophagy gene Ulk1 in Atg5-independent alternative macroautophagy2010
- Author(s)
  Shimizu S.
- Organizer
  Gordon Conference
- Place of Presentation
  イタリア
- Year and Date
  2010-04-29
- Data Source
  KAKENHI-PROJECT-22247016
[Presentation] Discovery of AtgS/Atg7-independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  6^<th> Institute network symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21659076
[Presentation] Discovery of Atg5/Atg7-independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  6^<th> Institute network symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] Multiple mechanisms of cell death and their regulation by mitochondria2010
- Author(s)
  S.Shimizu
- Organizer
  第74回日本循環器学会
- Place of Presentation
  京都
- Year and Date
  2010-03-05
- Data Source
  KAKENHI-PROJECT-21659076
[Presentation] Various Types of CellDeath and Autophagy2010
- Author(s)
  Shimizu S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23657084
[Presentation] A critical role for the autophagy gene Ulk1 in Atg5- independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  Gordon Conference
- Place of Presentation
  Lucca, Italy
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] A critical role for the autophagy gene U1k1 in Atg5- independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  Gordon Conference
- Place of Presentation
  Italy
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-21659076
[Presentation] Discovery of Atg5/Atg7-independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  6^<th> Institute network symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PUBLICLY-22121505
[Presentation] Discovery of AtgS/Atg7-independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  6^<th> Institute network symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] A critical role for the autophagy gene Ulkl in Atg5- independent alternative macroautophagy2010
- Author(s)
  S.Shimizu
- Organizer
  Gordon Conference
- Place of Presentation
  Lucca, Italy
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PUBLICLY-22020009
[Presentation] 1. Multiple mechanisms of cell death and their regulationby Bcl-22008
- Author(s)
  Shigeomi Shimizu
- Organizer
  JAACT2008
- Place of Presentation
  Fukuoka
- Year and Date
  2008-11-25
- Data Source
  KAKENHI-PROJECT-19659349
[Presentation] MITOCHONDRIA and NON-APOPTOTIC CELL DEATH.2007
- Author(s)
  Shimizu S
- Organizer
  4th Annual Meeting of Asian Society for Mitochondrial Research and Medicine,
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-18023024
[Presentation] Physiological Role of Atg5-independent macroautophagy
- Author(s)
  Shimizu S
- Organizer
  The 16th Northeastern Asian Symposium
- Place of Presentation
  Busan, Korea
- Year and Date
  2014-12-19 – 2014-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Physiological Role of Atg5-independent macroautophagy
- Author(s)
  Shimizu S
- Organizer
  The 16th Northeastern Asian Symposium
- Place of Presentation
  Busan, Korea
- Year and Date
  2014-12-19 – 2014-12-20
- Invited
- Data Source
  KAKENHI-PROJECT-22229002
[Presentation] Development of Molecularly Targeted Anticancer Agents Based on the Regulation of Autophagic Cell Death
- Author(s)
  Shimizu S
- Organizer
  The Uehara Memorial Foundation Symposium 2014
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2014-06-15 – 2014-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-25670139
[Presentation] Development of Molecularly Targeted Anticancer Agents Based on the Regulation of Autophagic Cell Death
- Author(s)
  Shimizu S
- Organizer
  The Uehara Memorial Foundation Symposium 2014
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2014-06-15 – 2014-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-22229002

1. TSUJIMOTO Yoshihide (70132735)

# of Collaborated Projects: 4 results

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2. EGUCHI Yutaka (20243206)

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# of Collaborated Projects: 3 results

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7. KONISHI Akimitsu (50381877)

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59. 辻岡政経

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Shimizu Shigeomi 清水 重臣

SHIMIZU Shigeomi 清水 重臣

Research Projects

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Co-Researchers

生体におけるゴルジ体関連分解GOMEDの役割と関連疾患Principal Investigator

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Changes in biological responses caused by qualitative differences in self-recognition receptorsPrincipal Investigator

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Analysis of the Mechanism of Protein Lifetime Determination in the Golgi apparatusPrincipal Investigator

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Biological role of GOMED and related diseasesPrincipal Investigator

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Alteration of Biological Responses by Different Qualities of Self-Recognition ReceptorsPrincipal Investigator

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細胞機能を司るオルガネラ・ゾーンの解読Principal Investigator

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第２のマクロオートファジーGOMEDの生体での役割Principal Investigator

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Novel role of Golgi apparatus for non-cell autonomous eventsPrincipal Investigator

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The effects of Atg5-independent autophagy activator on DSS-induced colitis in mice

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Regulation of brain aging by alternative autophagyPrincipal Investigator

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Analysis of "Response zone" and " Communication zone" in mitochondria and Golgi apparatusPrincipal Investigator

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Toward an integrative understanding of functional zones in organellesArea Organizer

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Toward an integrative understanding of functional zones in organellesPrincipal Investigator

Principal Investigator

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Shimizu Shigeomi 清水重臣

SHIMIZU Shigeomi 清水重臣