TADA Toshiji 多田俊治

… Alternative Names

多田俊治タダトシジ

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Researcher Number	70275288
Other IDs
Affiliation (based on the past Project Information) *help	2016: 大阪府立大学, 理学系研究科, 客員研究員 2015 – 2016: 大阪府立大学, 理学(系)研究科(研究院), 客員研究員 2014: 大阪府立大学, 理学(系)研究科(研究院), 教授 2013: 大阪府立大学, 理学系研究科, 教授 2011: 大阪府立大学, 大学院・理学系研究科, 教授 … More 2009 – 2011: Osaka Prefecture University, 理学系研究科, 教授 2007: 大阪府立大学, 理学系研究科, 教授 2001 – 2003: 大阪府立大学, 先端科学研究所, 助教授 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Chemical biology Except Principal Investigator Biophysics / 応用微生物学・応用生物化学 / Structural biochemistry
Keywords	Principal Investigator DFG motif / Ｘ線結晶構造解析 / MEK1 / 活性制御機構 / MEK / MAPキナーゼ / タンパク質結晶学 / 環境対応 / 生体機能利用 / 分析科学 … More / 蛋白質 / 構造活性相関 / 昆虫 / 分子認識 / 構造生物化学 / 蛋白質結晶学 … More Except Principal Investigator FBP / SBPase / FBPase / neuroserpin / drug design / neurodegeneration / dementia / serpin / alzheimer / inhibitor / tPA / Dual activity / Allosteric regulation / X-Ray structure analysis / Calvin cycle / Cyanobacteria / セレノメチオニン / 変異体 / 異常分散 / 結晶化 / SB Pace / FB Pace / GAPDH / 放射光 / 結晶構造 / アロステリック効果 / X線構造解析 / 光合成炭素還元系 / ラン藻 / コンフォメーション病 / 神経変性 / フォールディング / 痴呆 / 蛋白質 / 生物物理 / 脳神経疾患 / Serpin / Conformational Diseases / Protein Folding / Dementia / Protein folding / serpins / ovalbumin / folding / conformational diseases / 中性子線結晶構造解析 / 超高分解能X線結晶構造解析 / 超高分解能X線構造解析 / MAPキナーゼ / ドラッグデザイン / 中性子線構造解析 / X線結晶構造解析 / 阻害剤 / JNK1 Less

Structural basis for the reguration mechanism of MAP kinase activityPrincipal Investigator
- Principal Investigator
  
  Tada Toshiji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka Prefecture University
A new strategy to develop therapeutic agents for neurodegenerative diseases by structural biology
- Principal Investigator
  
  Onda Maki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Osaka Prefecture University
New strategy for the development of drugs to treat serpinopathies based on structural biology
- Principal Investigator
  
  ONDA Maki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Osaka Prefecture University
Ligand recognition mechanism of the ecdysone hormone receptor for the molecular design of a new pesticidePrincipal Investigator
- Principal Investigator
  
  TADA Toshiji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Osaka Prefecture University
Ultra-high resolution X-ray and neutron analyses aimed for producing highly selective JNK1 inhibitors
- Principal Investigator
  
  KINOSHITA Takayoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka Prefecture University
Structure of a Dual Activity FBP/SBPase from Synechococcus PCC 7942
- Principal Investigator
  
  NISHIMURA Keiichiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Osaka Prefecture University

All 2015 2012 2011 2009 2008 2007 2001 Other

All Journal Article Presentation

[Journal Article] Crystal structure of the catalase-peroxidase KatG W78F mutant from Synechococcus elongatus PCC7942 in complex with the antitubercular pro-drug isoniazid2015
- Author(s)
  Kamachi S., Hirabayashi K., Tamoi M., Shigeoka S., Tada T., Wada K.
- Journal Title
  
  FEBS Letters
  
  Volume: 589(1) Issue: 1 Pages: 131-137
- DOI
  10.1016/j.febslet.2014.11.037
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J01292, KAKENHI-PROJECT-25840023, KAKENHI-PROJECT-26440035
[Journal Article] The crystal structure of isoniazid-bound KatG catalase-peroxidase from Synechococcus elongatus PCC79422015
- Author(s)
  Kamachi S., Hirabayashi K., Tamoi M., Shigeoka S., Tada T., Wada K.
- Journal Title
  
  FEBS Journal
  
  Volume: 282(1) Issue: 1 Pages: 54-64
- DOI
  10.1111/febs.13102
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J01292, KAKENHI-PROJECT-25840023, KAKENHI-PROJECT-26440035
[Journal Article] Crystal structure of human mono-phosphorylated ERK1 at Tyr2042008
- Author(s)
  T. Kinoshita, I. Yoshida, S. Nakae, K. Okita, M. Gouda, M. Matsubara, K. Yokota, H. Ishiguro, T. Tada
- Journal Title
  
  Biochem. Biopys. Res. Commun. 377
  
  Pages: 1123-1127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570111
[Journal Article] Crystallization of porcine pancreatic elastase and preliminary neutron diffraction experiment2007
- Author(s)
  T. Kinoshita, T. Tamada, K. Imai, K. Kurihara, T. Ohhara, T. Tada, R. Kuroki
- Journal Title
  
  Acta Cryst. F63
  
  Pages: 315-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570111
[Journal Article] Purification, Crystallization and Preliminary X-Ray Diffraction Analysis of the Fructose-1,6-/sedoheptulose-1,7-bisphosphatase of Synechococcus PCC 79422001
- Author(s)
  Y.Nakamura, T.Tada, K.Wada, T.Kinoshita, M.Tamoi, S.Shigeoka, K.Nishimura
- Journal Title
  
  Acta Crystallographica D57
  
  Pages: 454-456
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13660098
[Journal Article] Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond
- Author(s)
  T. Tamada, T. Kinoshita, K. Kurihara, M. Adachi, T. Ohhara, K. Imai, R. Kuroki, T. Tada
- Journal Title
  
  J. Am. Chem. Soc. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570111
[Presentation] 疑似リン酸化によるMEK1の構造変化2015
- Author(s)
  中江摂，白井剛，桐井康行，多田俊治
- Organizer
  平成27年度日本結晶学会年会
- Place of Presentation
  大阪府立大学 (大阪府堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-26440035
[Presentation] オボアルブミンのポリマー化機構2012
- Author(s)
  Y. Kawamoto, T. Tada, M. Onda.
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都女子大学
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-23570195
[Presentation] Configuration of neuroserpin polymers2012
- Author(s)
  J. Zhang, S.Takehara, T. Tada, M. Onda.
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-23570195
[Presentation] On-column refoldingによるループ挿入型ニューロセルピンの調製2011
- Author(s)
  X. Yang, S.Takehara, T. Tada, M. Onda.
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23570195
[Presentation] On-column refoldingによるループ挿入型ニューロセルピンの調製2011
- Author(s)
  楊暁艶、竹原清日、多田俊治、恩田真紀
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23570195
[Presentation] ニューロセルピンのポリマー化は3本の-ストランドのスワッピングにより起こる2011
- Author(s)
  張娟、竹原清日、多田俊治、恩田真紀
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23570195
[Presentation] 病原性ニューロセルピン変異体の熱安定型異性体の調製2011
- Author(s)
  楊暁艶、竹原清日、多田俊治、恩田真紀
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪）
- Data Source
  KAKENHI-PROJECT-23570195
[Presentation] ニューロセルピン・ポリマーの構造特性：新しいセルピンのポリマー化モデル2011
- Author(s)
  張娟、竹原清日、多田俊治、恩田真紀
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪）
- Data Source
  KAKENHI-PROJECT-23570195
[Presentation] オボアルブミンのポリマー化：阻害活性のないセルピンのポリマー形成2011
- Author(s)
  川本好博、多田俊治、恩田真紀
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23570195
[Presentation] 中性子構造解析を目的とした変異体human c-Jun N-terminal kinaseの結晶調製法の探索2009
- Author(s)
  仲庭哲津子、井上達矢、木下誉富、多田俊治、安達基泰、玉田太郎、黒木良太
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本市
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-19570111
[Presentation] キイロショウジョウバエEcR/USPの結晶化2009
- Author(s)
  蒲池沙織, 中江摂, 原田俊幸, 小倉岳彦, 中川好秋, 多田俊治
- Organizer
  日本農芸化学会関西・中四国・西日本支部合同大会
- Place of Presentation
  沖縄
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-21603011
[Presentation] エラスターゼおよび薬剤候補化合物複合体の中性子構造解析2007
- Author(s)
  玉田太郎、木下誉富、多田俊治、栗原和男、大原高志、黒木良太
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台市
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19570111
[Presentation] Structure-Based Drug Designの新展開-エラスターゼを題材として-2007
- Author(s)
  木下誉富、多田俊治、今井啓祐
- Organizer
  第7回蛋白質科学会ワークショップ「歩き始めた新しい構造研究プローブ」
- Place of Presentation
  仙台市
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19570111
[Presentation] エラスターゼおよび薬物候補化合物複合体の中性子構造解析2007
- Author(s)
  玉田太郎、木下誉富、大原高志、栗原和男、多田俊治、黒木良太
- Organizer
  日本中性子科学会第7回年会
- Place of Presentation
  九州大学
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-19570111
[Presentation] DFG-outコンフォメーションを持つMEK1構造
- Author(s)
  中江摂，藤原大佑，道幸勝也，白井剛，多田俊治
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26440035
[Presentation] MEK1活性抑制体のＸ線結晶構造解析
- Author(s)
  中江摂，徳弘桃子，道幸勝也，桐井康行，白井剛，多田俊治
- Organizer
  平成26年度日本結晶学会年会
- Place of Presentation
  東京大学
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-26440035
[Presentation] MEK1疑似活性体のＸ線結晶構造解析
- Author(s)
  道幸勝也，中江摂，白井剛，桐井康行，多田俊治
- Organizer
  平成26年度日本結晶学会年会
- Place of Presentation
  東京大学
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-26440035

1. KINOSHITA Takayoshi (90405340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. ONDA Maki (60311916)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. MIKAMI Bunzo (40135611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAKAGAWA Yoshiaki (80155689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. NAKAE SETSU (10749352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. NISHIMURA Keiichiro (70026558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 山崎正幸 (80397562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Lomas David A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Miranda Elena

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TADA Toshiji 多田 俊治

多田 俊治 タダ トシジ

Research Projects

Research Products

Co-Researchers

Structural basis for the reguration mechanism of MAP kinase activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new strategy to develop therapeutic agents for neurodegenerative diseases by structural biology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New strategy for the development of drugs to treat serpinopathies based on structural biology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ligand recognition mechanism of the ecdysone hormone receptor for the molecular design of a new pesticidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ultra-high resolution X-ray and neutron analyses aimed for producing highly selective JNK1 inhibitors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure of a Dual Activity FBP/SBPase from Synechococcus PCC 7942

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Crystal structure of the catalase-peroxidase KatG W78F mutant from Synechococcus elongatus PCC7942 in complex with the antitubercular pro-drug isoniazid2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The crystal structure of isoniazid-bound KatG catalase-peroxidase from Synechococcus elongatus PCC79422015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of human mono-phosphorylated ERK1 at Tyr2042008

Author(s)

Journal Title

Data Source

[Journal Article] Crystallization of porcine pancreatic elastase and preliminary neutron diffraction experiment2007

Author(s)

Journal Title

Data Source

[Journal Article] Purification, Crystallization and Preliminary X-Ray Diffraction Analysis of the Fructose-1,6-/sedoheptulose-1,7-bisphosphatase of Synechococcus PCC 79422001

Author(s)

Journal Title

Description

Data Source

[Journal Article] Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond

Author(s)

Journal Title

Data Source

[Presentation] 疑似リン酸化によるMEK1の構造変化2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] オボアルブミンのポリマー化機構2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

TADA Toshiji 多田俊治

多田俊治タダトシジ

[Presentation] ニューロセルピンのポリマー化は3本の-ストランドのスワッピングにより起こる2011