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Shirouzu Mikako  白水 美香子

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… Alternative Names

白水 美香子  シロウズ ミカコ

SHIROUZU Mikako  白水 美香子

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Researcher Number 70280732
Other IDs
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, 副センター長
Affiliation (based on the past Project Information) *help 2016: 独立行政法人理化学研究所, 生命分子システム基盤研究領域, 上級研究員
2016: 理化学研究所, タンパク質機能・構造研究チーム, チームリーダー
2014: 独立行政法人理化学研究所, ライフサイエンス技術基盤研究センター, 副センター長
1996 – 1999: 理化学研究所, 細胞情報伝達研究室, 研究員
Review Section/Research Field
Principal Investigator
Functional biochemistry
Except Principal Investigator
Surgical dentistry / Plant nutrition/Soil science / Biological Sciences
Keywords
Principal Investigator
Ras / X線結晶解析 / Raf / シグナル伝達経路 / PC12細胞 / Raf-1 / RalGDS / Cdc42 / Rac
Except Principal Investigator
Ras … More / Raf-1 / RalGDS / 骨細胞 / 骨芽細胞 / ミトコンドリア / 細胞内輸送 / LAMP / アセンブリ / LAMP-2 / LAMP-1 / リソソーム / 転写後制御 / mRNA分解 / 上流ORF / uORF / 輸送体 / リボソーム / ホウ素 / シロイヌナズナ / 分子認識 / 蛋白質 / 構造生物学 / X線結晶構造解析 / 医薬品設計 / 免疫学 / タンパク質 / 立体構造 / ペプチド / HLA / EHドメイン / NMR法 / X線結晶解析 / Raf / NMR / Cys-rich domain / シグナル伝達経路 / 多次元NMR法 / PC12細胞 / Cdc42 / Rac Less
  • Research Projects

    (8 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (13 People)
  •  Analysis of sensing mechanisms of mineral nutrient through ribosome-RNA complex

    • Principal Investigator
      Tanaka Mayuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plant nutrition/Soil science
    • Research Institution
      The University of Tokyo
  •  Structural basis of LAMP2 aimed to modulate intracellular trafficking of lysosome

    • Principal Investigator
      Miki Yokoyama
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Structural analysis of HLA class I/II molecules

    • Principal Investigator
      YOKOYAMA Shigeyuki
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Ras蛋白質によるターゲット活性化のメカニズム

    • Principal Investigator
      横山 茂之
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  RasによるRafの活性化機構の解明Principal Investigator

    • Principal Investigator
      白水 美香子
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Rasタンパク質によるターゲット活性化のメカニズム

    • Principal Investigator
      横山 茂之
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  発癌型Rasに特徴的な細胞内情報伝達機構の解析

    • Principal Investigator
      YOKOYAMA Shigeyuki
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  阻害因子の設計をめざした細胞内情報伝達の制御ネットワークの解析Principal Investigator

    • Principal Investigator
      白水 美香子
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research

All 2016 2014

All Journal Article Presentation

  • [Journal Article] Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modes.2016

    • Author(s)
      Terasawa K, Tomabechi Y, Ikeda M, Ehara H, Kukimoto-Niino M, Wakiyama M, Podyma-Inoue KA, Rajapakshe AR, Watabe T, Shirouzu M, Hara-Yokoyama M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 479 Issue: 3 Pages: 489-495

    • DOI

      10.1016/j.bbrc.2016.09.093

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25463072, KAKENHI-PROJECT-26463087
  • [Journal Article] Structural Basis for the Specific Recognition of the Major Antigenic Peptide from the Japanese Cedar Pollen Allergen Cry j 1 by HLA-DP5.2014

    • Author(s)
      Kusano S, Kukimoto-Niino M, Satta Y, Ohsawa N, Uchikubo-Kamo T, Wakiyama M, Ikeda M, Terada T, Yamamoto K, Nishimura Y, Shirouzu M, Sasazuki T, Yokoyama S.
    • Journal Title

      J Mol Biol.

      Volume: 426 Issue: 17 Pages: 3016-3027

    • DOI

      10.1016/j.jmb.2014.06.020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22133001, KAKENHI-PLANNED-22133004, KAKENHI-PLANNED-22133005, KAKENHI-PLANNED-22133007, KAKENHI-PLANNED-22133009
  • [Presentation] HLA-DP5によるスギ花粉抗原Cry j 1の特異的認識に対する構造的基盤2014

    • Author(s)
      草野清輔、新野睦子、颯田葉子、大沢登、加茂友美、脇山素明、池田眞理子、寺田貴帆、山本健、西村泰治、白水美香子、笹月健彦、横山茂之
    • Organizer
      第37回 日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PLANNED-22133004
  • 1.  YOKOYAMA Shigeyuki (00159229)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 2.  HONMA Teruki (10466039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Tanaka Mayuki (80546292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Miki Yokoyama (70191533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  SAKAMOTO Kensaku (50240685)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KA 井上 (90302877)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Yokoyama Takeshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  TERASAWA Kazue
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  颯田 葉子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  山本 健
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  笹月 健彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  西村 康治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  PODYMA Katarzyna Anna
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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