• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Kinoh Hiroaki  喜納 宏昭

ORCIDConnect your ORCID iD *help
… Alternative Names

喜納 宏昭  キノウ ヒロアキ

Less
Researcher Number 70283067
Other IDs
Affiliation (Current) 2022: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 主幹研究員
Affiliation (based on the past Project Information) *help 2021: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 主幹研究員
2017 – 2019: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 主幹研究員
Review Section/Research Field
Principal Investigator
Tumor therapeutics / Basic Section 50010:Tumor biology-related
Keywords
Principal Investigator
ナノ治療薬 / 膵臓がん / がん幹細胞 / 難治癌 / K252a ミセル / スタウロスポリン / エピルビシン / ミセル / MDR-1 / 癌幹細胞阻害剤 … More / ナノミセル / ナノバイオ / 癌 / がん間質 / 免疫チェックポイント阻害剤 / 耐性克服 Less
  • Research Projects

    (2 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (24 People)
  •  Development of nano-therapeutic agents to overcome immune checkpoint inhibitor resistance due to tumor stroma of intractable cancerPrincipal Investigator

    • Principal Investigator
      喜納 宏昭
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
  •  Creation of novel nanomedicine targeting drug-resistant cancer stem cells in recurrent refractory cancerPrincipal Investigator

    • Principal Investigator
      Kinoh Hiroaki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine

All 2020 2019 2018 2017

All Journal Article Presentation Patent

  • [Journal Article] Nanomedicines blocking adaptive signals in cancer cells overcome tumor TKI resistance2020

    • Author(s)
      H. Kinoh, H. Shibasaki, X. Liu, T. Yamasoba, H. Cabral, K. Kataoka
    • Journal Title

      J. Control. Release

      Volume: 321 Pages: 132-144

    • DOI

      10.1016/j.jconrel.2020.02.008

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K19901
  • [Journal Article] Single-Stranded DNA-Packaged Polyplex Micelle as Adeno-Associated-Virus-Inspired Compact Vector to Systemically Target Stroma-Rich Pancreatic Cancer2019

    • Author(s)
      T. A. Tockary, W. Foo, A. Dirisala, Q. Chen, S. Uchida, S. Osawa, Y. Mochida, X. Liu, H. Kinoh, H. Cabral, K. Osada, K. Kataoka
    • Journal Title

      ACS Nano

      Volume: 13 Pages: 12732-12742

    • DOI

      10.1021/acsnano.9b04676

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18393, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K19901
  • [Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells2019

    • Author(s)
      Y. Yi, H. J. Kim, M. Zheng, P. Mi, M. Naito, B. S. Kim, H. S. Min, K. Hayashi, F. Perche, K. Toh, X. Liu, Y. Mochida, H. Kinoh, H. Cabral, K. Miyata, K. Kataoka
    • Journal Title

      Journal of Controlled Release

      Volume: 295 Pages: 268-277

    • DOI

      10.1016/j.jconrel.2019.01.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K18378, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18K18391
  • [Journal Article] Therapeutic polymersome nanoreactors with tumor-specific activable cascade reactions for cooperative cancer therapy2019

    • Author(s)
      W. Ke, J. Li, F. Mohammed, Y. Wang, K. Tou, X. Liu, P. Wen, H. Kinoh, Y. Anraku, H. Chen, K. Kataoka, Z. Ge,
    • Journal Title

      ACS Nano

      Volume: 13 Pages: 2357-2369

    • DOI

      10.1021/acsnano.8b09082

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H04742, KAKENHI-PROJECT-17K20094
  • [Journal Article] In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancer.2019

    • Author(s)
      Watanabe Sumiyo、Hayashi Kotaro、Toh Kazuko、Kim Hyun Jin、Liu Xueying、Chaya Hiroyuki、Fukushima Shigeto、Katsushima Keisuke、Kondo Yutaka、Uchida Satoshi、Ogura Satomi、Nomoto Takahiro、et al.
    • Journal Title

      Nat. Commun.

      Volume: 10 Pages: 1-13

    • DOI

      10.1038/s41467-019-09856-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K18383, KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-19K12799, KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-18H04163, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-18H02797, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-17H04743, KAKENHI-PROJECT-17K07234
  • [Journal Article] Effective treatment of drug resistant recurrent breast tumors harboring cancer stem-like cells by staurosporine/epirubicin co-loaded polymeric micelles2017

    • Author(s)
      J. Zhang, H. Kinoh, L. Hespel, X. Liu, S. Quader, J. Martin, T. Chida, H. Cabral, K. Kataoka,
    • Journal Title

      Journal of Controlled Release

      Volume: 264 Pages: 127-135

    • DOI

      10.1016/j.jconrel.2017.08.025

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16F16731, KAKENHI-PROJECT-16K12904
  • [Journal Article] cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells.2017

    • Author(s)
      Miyano Kazuki、Cabral Horacio、Miura Yutaka、Matsumoto Yu、Mochida Yuki、Kinoh Hiroaki、Iwata Caname、Nagano Osamu、Saya Hideyuki、Nishiyama Nobuhiro、Kataoka Kazunori、Yamasoba Tatsuya
    • Journal Title

      J. Control. Release

      Volume: 261 Pages: 275-286

    • DOI

      10.1016/j.jconrel.2017.06.021

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17KT0048, KAKENHI-PROJECT-16K11226, KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-17H01401, KAKENHI-PROJECT-15H04635, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-16H05422, KAKENHI-PROJECT-17H06641, KAKENHI-PROJECT-16F16058, KAKENHI-PROJECT-16F16407, KAKENHI-PROJECT-16K15104
  • [Patent] 脳腫瘍治療薬2019

    • Inventor(s)
      喜納宏昭、片岡一則
    • Industrial Property Rights Holder
      公益財団法人 川崎市産業振興財団
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Patent] 医薬組成物2018

    • Inventor(s)
      カダール・サビーナ,カブラル・オラシオ, 喜納宏昭, 片岡一則
    • Industrial Property Rights Holder
      カダール・サビーナ,カブラル・オラシオ, 喜納宏昭, 片岡一則
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-030208
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Patent] ポリマー、ポリマーの製造方法、薬物複合体及びミセル2018

    • Inventor(s)
      カダール・サビーナ,カブラル・オラシオ, 喜納宏昭, 片岡一則
    • Industrial Property Rights Holder
      カダール・サビーナ,カブラル・オラシオ, 喜納宏昭, 片岡一則
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-030209
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Patent] 薬物複合体、ミセル、及び医薬組成物2018

    • Inventor(s)
      カダール・サビーナ,カブラル・オラシオ, 喜納宏昭, 片岡一則
    • Industrial Property Rights Holder
      カダール・サビーナ,カブラル・オラシオ, 喜納宏昭, 片岡一則
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-030200
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Patent] ポリマー、ポリマーの製造方法、及び薬物複合体2017

    • Inventor(s)
      カダール・サビーナ,カブラル・オラシオ, 喜納宏昭, 片岡一則
    • Industrial Property Rights Holder
      カダール・サビーナ,カブラル・オラシオ, 喜納宏昭, 片岡一則
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Presentation] Targeting Intractable Cancers Using Extracellular pH sensitive NanoMedicine2019

    • Author(s)
      S. Quader, X. Liu, H. Kinoh, K. Kataoka
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Presentation] (+)-JQ-1誘導体を内包したpH反応性新規ナノ粒子のc-Myc高発現腫瘍に対する抗腫瘍効果2019

    • Author(s)
      柴崎仁志、喜納宏昭、S. Quader、持田祐希、L. Xueying、C. Horacio、松本有、片岡一則、山岨達也
    • Organizer
      第120回日本耳鼻咽喉科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Presentation] Novel pH-sensitive Nanomedicine Conjugating (+)-JQ-1 Homolog Inhibits the Growth of the Head and Neck Cancer which Overexpress c-Myc2019

    • Author(s)
      Hiroaki Kinoh
    • Organizer
      12th Annual Symposium on Nanotechnology,
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Presentation] Nanomedicine Loading Staurosporine homolog (K252a-hydrozyde) overcomes osimertinib resistance in non small lung cancer2019

    • Author(s)
      喜納宏昭、柴崎仁志、S. Quader、X. Liu、H. Cabral、片岡一則
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Presentation] 薬剤耐性および再発/転移する難治癌に対して著効するナノDDS製剤の開発,2018

    • Author(s)
      喜納宏昭
    • Organizer
      第27回日本がん転移学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Presentation] pH応答性抗癌剤ナノミセルは、 PTEN/VHL発現欠失スニチニブ耐性腎癌に対しても有効である。2017

    • Author(s)
      喜納宏昭、H. Cabral、北村貴美子、片岡一則
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Presentation] pH応答性スタウロスポリン内包エピルビシンミセルは、スニチニブ耐性獲得腎癌に対しても高い抗腫瘍効果を示す2017

    • Author(s)
      喜納宏昭、H. Cabral、北村貴美子、片岡一則
    • Organizer
      第33回DDS学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K07234
  • [Presentation] pH応答性ナノミセルは、 PTEN/VHL発現欠失スニチニブ耐性腎癌に対して有効であり、転移に対しても著効を示す2017

    • Author(s)
      喜納宏昭、片岡一則
    • Organizer
      第21回日本がん分子標的学会
    • Data Source
      KAKENHI-PROJECT-17K07234
  • 1.  劉 学瑩 (30777470)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  Cabral Horacio (10533911)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 3.  Quader Sabina (90749699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  OSADA Kensuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 5.  MATSUMOTO Yu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  Miyano Kazuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  Horacio Cabral
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  MIURA Yutaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  ANRAKU Yasutaka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  KANO Mitsunobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  MARTIN JOHN
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 12.  内田 智士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 13.  ディリサラ アンジャネユル
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  持田 祐希
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 15.  佐谷 秀行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  青木 伊知男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  西山 伸宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 18.  Kim HyunJin
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  宮田 完二郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  片岡 一則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  林 光太朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 22.  野本 貴大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  武元 宏泰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  近藤 豊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi