TAI Akihiro 田井章博

… Alternative Names

田井章博タイアキヒロ

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Researcher Number	70284081
Other IDs
External Links
Affiliation (Current)	2025: 徳島大学, 大学院社会産業理工学研究部(生物資源産業学域), 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 徳島大学, 大学院社会産業理工学研究部(生物資源産業学域), 教授 2016 – 2019: 県立広島大学, 生命環境学部, 教授 2007: Okayama University, 大学院・医歯薬学総合研究科, 准教授 2005 – 2006: 岡山大学, 大学院医歯薬学総合研究科, 助教授 1998 – 2001: 岡山大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Food science / Biological pharmacy Except Principal Investigator Basic Section 38040:Bioorganic chemistry-related / Agricultural chemistry and related fields / Bioorganic chemistry / Biological pharmacy
Keywords	Principal Investigator アシル化 / コラーゲン合成 / ラジカル捕捉 / 抗酸化 / HPLC / グルコシル化 / アスコルビン酸誘導体 / アスコルビン酸類似体 / FcγR介在性貧食 / TNF-α … More / IL-1β / 活性酸素 / レクチン / Fcγ R介在性貧食 / 糖鎖修飾 / Gcグロブリン / マクロファージ … More Except Principal Investigator 神経突起伸長作用 / 構造活性相関 / 6-Acyl-AA-2G / AA-2G / ホモイソフラボノイド / AChE阻害作用 / 脳機能障害の改善 / 神経突起伸長促進作用 / アセチルコリンエステラーゼ阻害活性 / ホモイソフラバン / シロイヌナズナ / プロテオーム / アスコルビン酸プローブ / アスコルビン酸結合タンパク質 / 安定型アスコルビン酸プローブ / 植物 / ビタミンＣ / 有機合成 / PTP 1B阻害活性 / 生理活性 / 構造訂正 / PTP 1B阻害活性物質の合成 / Ullmannエーテル合成 / 全合成 / PTP1B阻害活性物質 / Ullumannエーテル合成 / プロテインチロシンホスファターゼ1B阻害剤 / 2型糖尿病 / 有機合成化学 / 生物活性物質 / 天然物合成 / lipophilic ascorbate derivatives / stable ascorbate derivatives / ascorbic acid / neuro-immune cross-talks / 親油性安定型アスコルビン酸誘導体 / 安定型アスコルビン酸誘導体 / アスコルビン酸 / 神経・免疫クロストーク Less

Research to create homoisoflavonoid analogues with both AChE inhibitory and neurite outgrowth promoting activities.
- Principal Investigator
  
  野下俊朗
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Gihu University of Medical Science
Screening of ascorbate-binding proteins in plant using novel stable ascorbate probes
- Principal Investigator
  
  Ishikawa Takahiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Agricultural chemistry and related fields
- Research Institution
  Shimane University
Syntheses and structure-activity relationship studies of diaryl ether type PTP 1B inhibitors
- Principal Investigator
  
  Noshita Toshiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Prefectural University of Hiroshima
真菌類由来アスコルビン酸類似体の動物における機能解明並びに生物学的利用Principal Investigator
- Principal Investigator
  
  田井章博
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Okayama University
Studies on the factors that can regulate neuro-immune-cross talks
- Principal Investigator
  
  YAMAMOTO Itaru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  OKAYAMA UNIVERSITY
常在性および炎症性マクロファージの活性化機構に関する研究Principal Investigator
- Principal Investigator
  
  田井章博
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Okayama University

All 2020 2018 2008 2007 2006

All Journal Article Presentation

[Journal Article] Affinity resins as new tools for identifying target proteins of ascorbic acid2018
- Author(s)
  Iwaoka Yuji、Nishino Kohei、Ishikawa Takahiro、Ito Hideyuki、Sawa Yoshihiro、Tai Akihiro
- Journal Title
  
  The Analyst
  
  Volume: 143 Issue: 4 Pages: 874-882
- DOI
  10.1039/c7an01592e
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19239
[Journal Article] Synthetic and in vitro studies to indicate that the structure of the PTP1B inhibitor isolated from Acanthopanax senticosus requires reinvestigation2018
- Author(s)
  Noshita Toshiro、Onishi Ryoya、Miura Kaori、Hamada Yoshitomo、Nishino Yuki、Ouchi Hidekazu、Tai Akihiro
- Journal Title
  
  Phytochemistry Letters
  
  Volume: 27 Pages: 214-218
- DOI
  10.1016/j.phytol.2018.07.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07720
[Journal Article] Antioxidant properties of 2-O-β-D-glucopyranosyl-Lascorbic acid2008
- Author(s)
  J. Takebayashi, Y. Yagi, R. Ishii, S. Abe, K. Yamada and A. Tai
- Journal Title
  
  Biosic. Biotechnol. Biochem. 72(印刷中)
- NAID
  10027528885
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17780103
[Journal Article] 親油性安定型アスコルビン酸誘導体の創製とその特性に関する研究2008
- Author(s)
  田井章博
- Journal Title
  
  ビタミン 82
  
  Pages: 151-160
- NAID
  110006646076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17780103
[Journal Article] Determination of ascorbic and its related compounds in foods and beverages by hydrophilic interaction liquid chromatography2007
- Author(s)
  A. Tai and E. Gohda
- Journal Title
  
  J. Chromatogr. B Analyt. Technol. Biomed, Life Sci. 853
  
  Pages: 214-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17780103
[Journal Article] 2-O-α-D-Glucopyranosyl-L-ascorbic acid scavenges 1,1-diphenyl-2-picrylhydrazyl radicals via a covalent adduct formation2007
- Author(s)
  J.Takebayashi, R.Asano, Y.Nakae, M.Saito, E.Gohda, I.Yamamoto, A.Tai
- Journal Title
  
  Biosci.Biotechnol.Biochem. 71(3)
  
  Pages: 754-760
- NAID
  10027512868
- Data Source
  KAKENHI-PROJECT-17780103
[Journal Article] 親油性安定型アスコルビン酸誘導体の開発と応用2007
- Author(s)
  田井章博
- Journal Title
  
  バイオサイエンスとインダストリー 65(3)
  
  Pages: 132-133
- NAID
  10018852581
- Data Source
  KAKENHI-PROJECT-17780103
[Journal Article] Inhibition of free radical-induced erythrocyte hemolysis by 2-O-substituted ascorbic acid derivatives2007
- Author(s)
  J. Takebayashi, H, Kaji, K. Ichiyama, K. Makino, E. Gohda, I. Yamamoto and A, Tai
- Journal Title
  
  Free Radic. Biol. Med. 43
  
  Pages: 1156-1164
- NAID
  110006646081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17780103
[Journal Article] An isocratic HPLC method for the simultaneous determination of novel stable lipophilic ascorbic acid derivatives and their metabolites2006
- Author(s)
  A.Tai, J.Takebayashi, A.Ueno, E.Gohda, I.Yamamoto
- Journal Title
  
  J.Chromatogr.B Analyt.Technol.Biomed.Life Sci. 840(1)
  
  Pages: 38-43
- NAID
  10025785706
- Data Source
  KAKENHI-PROJECT-17780103
[Journal Article] Characterization of the radical-scavenging reaction of 2-O-substituted ascorbic acid derivatives, AA-2G, AA-2P, and AA-2S : a kinetic and stoichiometric study2006
- Author(s)
  J.Takebayashi, A.Tai, E.Gohda, I.Yamamoto
- Journal Title
  
  Biol.Pharm.Bull. 29(4)
  
  Pages: 766-771
- NAID
  110005602183
- Data Source
  KAKENHI-PROJECT-17780103
[Presentation] アフィニティー樹脂によるシロイヌナズナアスコルビン酸結合タンパク質の探索2020
- Author(s)
  西原好美、西野耕平、岩岡裕二、丸田隆典、小川貴央、重岡成、田井章博、澤嘉弘、石川孝博
- Organizer
  日本農芸化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-17K19239
[Presentation] アスコルビン酸標的タンパク質の探索を指向した新規アフィニティーゲルの創製2018
- Author(s)
  岩岡裕二，西野耕平，石川孝博，伊東秀之，澤　嘉弘，田井章博
- Organizer
  日本ビタミン学会第70回大会
- Data Source
  KAKENHI-PROJECT-17K19239
[Presentation] アフィニティーゲルによる植物アスコルビン酸結合タンパク質の包括的探索2018
- Author(s)
  西原好美、西野耕平、岩岡裕二、小川貴央、丸田隆典、田井章博、石川孝博
- Organizer
  日本農芸化学会中四国支部2018年度支部大会
- Data Source
  KAKENHI-PROJECT-17K19239
[Presentation] アスコルビン酸標的タンパク質の探索ツールとしての新規アフィニティーゲルの創製2018
- Author(s)
  岩岡裕二，西野耕平，石川孝博，伊東秀之，澤　嘉弘，田井章博
- Organizer
  第１５５回ビタミンC研究委員会
- Data Source
  KAKENHI-PROJECT-17K19239
[Presentation] エゾウコギから単離されたPTP1B阻害物質の提出構造は誤りである2018
- Author(s)
  大西良弥　三浦香織　濱田義知　齊藤安貴子　大内秀一　田井章博　野下俊朗
- Organizer
  日本農芸化学会中四国支部第51回講演会
- Data Source
  KAKENHI-PROJECT-16K07720
[Presentation] 親油性安定型アスコルビン酸誘導体の創製とその特性に関する研究2007
- Author(s)
  田井章博
- Organizer
  日本ビタミン学会第59回大会
- Place of Presentation
  佐世保
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-17780103

1. Noshita Toshiro (50285574)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. YAMAMOTO Itaru (20028848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Ishikawa Takahiro (60285385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

TAI Akihiro 田井 章博

田井 章博 タイ アキヒロ

Research Projects

Research Products

Co-Researchers

Research to create homoisoflavonoid analogues with both AChE inhibitory and neurite outgrowth promoting activities.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Screening of ascorbate-binding proteins in plant using novel stable ascorbate probes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Syntheses and structure-activity relationship studies of diaryl ether type PTP 1B inhibitors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

真菌類由来アスコルビン酸類似体の動物における機能解明並びに生物学的利用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the factors that can regulate neuro-immune-cross talks

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

常在性および炎症性マクロファージの活性化機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Affinity resins as new tools for identifying target proteins of ascorbic acid2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthetic and in vitro studies to indicate that the structure of the PTP1B inhibitor isolated from Acanthopanax senticosus requires reinvestigation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antioxidant properties of 2-O-β-D-glucopyranosyl-Lascorbic acid2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 親油性安定型アスコルビン酸誘導体の創製とその特性に関する研究2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Determination of ascorbic and its related compounds in foods and beverages by hydrophilic interaction liquid chromatography2007

Author(s)

Journal Title

Data Source

[Journal Article] 2-O-α-D-Glucopyranosyl-L-ascorbic acid scavenges 1,1-diphenyl-2-picrylhydrazyl radicals via a covalent adduct formation2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 親油性安定型アスコルビン酸誘導体の開発と応用2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Inhibition of free radical-induced erythrocyte hemolysis by 2-O-substituted ascorbic acid derivatives2007

Author(s)

Journal Title

NAID

Data Source

TAI Akihiro 田井章博

田井章博タイアキヒロ