Akimoto Kazunori 秋本和憲

… Alternative Names

AKIMOTO Kazunori 秋本和憲

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Researcher Number	70285104
Other IDs
Affiliation (Current)	2025: 東京理科大学, 薬学部生命創薬科学科, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 東京理科大学, 薬学部生命創薬科学科, 教授 2015 – 2017: 東京理科大学, 薬学部生命創薬科学科, 准教授 2012 – 2015: 東京理科大学, 薬学部, 准教授 2012: 東京理科大学, 薬学部生命創薬科学科, 准教授 2011: 横浜市立大学, 大学院・医学研究科, 助教 … More 2008 – 2011: Yokohama City University, 医学部, 助教 2007: 横浜市立大学, 医学研究科, 助教 1997 – 2006: 横浜市立大学, 医学部, 助手 2004: 横浜市立大学, 医学, 助手 1999: 横浜市立大学, 医学部・第2生化学, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Functional biochemistry / Living organism molecular science / Developmental biology / Biological Sciences / Molecular biology / Cell biology Except Principal Investigator Human pathology / General medical chemistry / Functional biochemistry … More / Biological Sciences / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Obstetrics and gynecology / Dermatology / Surgical dentistry / Cell biology / Living organism molecular science / Urology Less
Keywords	Principal Investigator aPKC / 細胞極性 / 発がん / 器官形成 / 患者層別化 / 癌ゲノム医療 / ALDH1陽性乳癌幹細胞 / 公共の癌ゲノミクスデータ / 層別化 / データサイエンス手法 … More / 解糖系 / 癌幹細胞 / 公共の癌ゲノムデータ / 癌の層別化 / breast cancer / Cell polarity / 形態形成 / 細胞情報伝達機構 / 初期発生 / ジーンターゲッティング / Atypical Protein Kinase C / loxP / Cre / p70S6キナーゼ / P70S6キナーゼ … More Except Principal Investigator aPKC / ASIP / 細胞極性 / PAR-6 / PAR-3 / 上皮 / 非対称分裂 / ATPase / mRNA surveillance / mRNA degradation / ATPアーゼ / リン脂質キナーゼ / mRNA分離 / RNAヘリカーゼ / プロテインキナーゼ / p53 / mRNAサーベイランス / ナンセンス変異 / 子宮頸癌 / aPKCλ/ι / 前立腺癌 / 極性 / 線虫 / RNA helicase / PIK remated protein kinase / protein kinase / P53 / nonsense mutation / epithelia / 免疫組織化学 / IL-6 / 乳癌 / ドラッグリポジショニング / 非定型プロテインキナーゼ / 難治性乳がん / 抗腫瘍活性 / 浸潤 / オーラノフィン / ヘパラナーゼ / aPKC C / 子宮頸部上皮内病変 / 子宮頸部異形成 / 子宮頸がん / nonsense mutaion / RNA helices / PIK remitted protein kinas / protein kinas / NMD / ADPアーゼ / リン脂質類似キナーゼ / mRNA分解 / cell polarity / Asymmetric division / Lg1 / polarity / asymmetric cell division / C.elegans / LST / HPV / Immunohistochemistry / Cancer / GLOI / 腫瘍化 / CIN / 幹細胞 / 皮膚発癌 / 創傷治癒 / 皮膚幹細胞 / 毛包形成 / 遺伝子改変マウス / 脱毛 / 休眠 / 毛包幹細胞 / プロテインキナーゼC / 口腔がん / Cancer stem cell / 口腔扁平上皮癌 / 膵癌 / 難治癌 / 癌細胞 / IL6 / 発生・文化 / 発生・分化 / 細胞・組織 / 分化 / 発生 / シグナル伝達 / 組織 / 細胞 / 再生医学 / 癌 / 翻訳後修飾 / 複合体 / タンパク質 / プロテオミクス / aPKC λ / aPKCλ / 細胞極性制御分子 / 腫瘍学 / aPKC-PAR系 / 乳がん / 胃がん / 前立腺がん / 上皮細胞 / MDCK細胞 / 動物極 / 卵母細胞 / ツメガエル / PAR / PKC Less

Gene expression mechanism of glycosaminoglycan-degrading enzymes in refractory breast cancer
- Principal Investigator
  
  東恭平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo University of Science
Elucidation of a novel regulatory axis of glycolysis in cancer stem cells based on cancer genomics database analysisPrincipal Investigator
- Principal Investigator
  
  Akimoto Kazunori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tokyo University of Science
Role of the cell polarity regulator aPKC in uterine cervical cancer and cervical intraepithelial lesion.
- Principal Investigator
  
  MARUYAMA Yasuyo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yokohama City University
Role of aPKC-IL6 pathway, especially in prostatic and berast cancers
- Principal Investigator
  
  NAGASHIMA Yoji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Women's Medical University
Mechanism for the maintenance of skin stem cells by a cell polarity protein
- Principal Investigator
  
  OSADA Shin-Ichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Akita University
  Nippon Medical School
Role and possibility as a therapeutic target of aPKClambda/iota in intractable cancers
- Principal Investigator
  
  NAGASHIMA Yoji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Yokohama City University
Overexpression of the atypical protein kinase C rambda/iota in oral squamous cell carcinoma is associated with degrees of malignancy
- Principal Investigator
  
  KOIZUMI Toshiyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Yokohama City University
Molecular mechanisms of the polarity-regulating signaling
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Yokohama City University
Analysis of the molecules of cell polarity in associated with hormone
- Principal Investigator
  
  KUBOTA Yoshinobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Yokohama City University
Structure and function of multifunctional protein complex regulating cell polarity
- Principal Investigator
  
  KAWASAKI Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Yokohama City University
Regulation of Cell polarity by aPKC dependent gene expressionPrincipal Investigator
- Principal Investigator
  
  AKIMOTO Kazunori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University
Impact of the aPKC/PAR system on carcinogenesis and progression.
- Principal Investigator
  
  NAGASHIMA Yoji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Yokohama City University
Cell Polarity Signaling and Cancer
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Molecular mechanism of mammalian mRNA surveillance
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Yokohama City University
細胞極性因子aPKClの哺乳類器官形成及び病態(発がん)における役割の解析Principal Investigator
- Principal Investigator
  
  秋本和憲
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Yokohama City University
Molecular mechanism of mammalian mRNA surveillance
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Yokohama City University Graduate School of Medical Science
細胞極性決定因子aPKC/ASIPの哺乳類初期発生及び器官形成における役割の解析Principal Investigator
- Principal Investigator
  
  秋本和憲
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Cre/loxPシステムを用いたaPKCの哺乳類初期発生及び器官形成における役割の解析Principal Investigator
- Principal Investigator
  
  秋本和憲
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Yokohama City University
Molecular mechanism of mammalian mRNA surveillance
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University
Signaling mechanism of epithelial cell-cell attachment and cell polarity.
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
脊髄動物の初期胚におけるPAR及びaPKCの動態と極性の決定機構
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Yokohama City University
コンディショナルジーンターゲッティングによるaPKC群の個体レベルでの機能解析Principal Investigator
- Principal Investigator
  
  秋本和憲
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Yokohama City University
Analyses of the universal molecular machinary involved in cell polarization
- Principal Investigator
  
  OHNO Shigeo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University School of Medicine
PI3-キナーゼ→aPKC群経路の標的蛋白の同定および細胞生理作用の解析Principal Investigator
- Principal Investigator
  
  秋本和憲
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Yokohama City University

[Book] 月刊　「Precision Medicine」11月号　リキッドバイオプシーによるゲノム医療情報論・統計解析手法を用いたがんゲノミクスデータ解析による乳がん患者層別化2021
- Author(s)
  秋本　和憲・多森　翔馬・翁長朝太郎・野崎　優香・本村　瞳・尾崎　綾栞・熊御雲・田畑耕治・佐藤圭子
- Total Pages
  4
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-20K07207
[Book] 「Precision Medicine」臨時増刊号　ゲノム情報とオミックス情報を活用した「予防医学」情報論・統計解析手法を用いたがんゲノミクスデータ解析による乳がん患者層別化2021
- Author(s)
  秋本　和憲・多森　翔馬・翁長朝太郎・野崎　優香・本村　瞳・尾崎　綾栞・熊御雲・田畑耕治・佐藤圭子
- Total Pages
  4
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-20K07207
[Book] 月刊　「細胞」　特集　ゲノムデータを駆使した医学研究　がんゲノミクスデータ解析を起点としたがん幹細胞の生存機構の解明2021
- Author(s)
  多森翔馬、本村瞳、野崎優香、佐藤圭子、秋本和憲
- Total Pages
  3
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20K07207
[Book] 月刊　「細胞」　１０月臨時増刊号　新規細胞死機構が制御する生体応答　　がんゲノミクスデータ解析を起点としたがん幹細胞の生存機構の解明2021
- Author(s)
  多森翔馬、本村瞳、野崎優香、尾崎　綾栞、翁長朝太郎、佐藤圭子、秋本和憲
- Total Pages
  3
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-20K07207
[Book] 図解　腫瘍薬学第１３章１０　（p534－552）2020
- Author(s)
  小茂田昌代、秋本和憲、斎藤光江
- Total Pages
  18
- Publisher
  南山堂
- ISBN
  9784525721619
- Data Source
  KAKENHI-PROJECT-20K07207
[Book] 図解　腫瘍薬学６章２-3 (p130-148)2020
- Author(s)
  秋本和憲
- Total Pages
  18
- Publisher
  南山堂
- ISBN
  9784525721619
- Data Source
  KAKENHI-PROJECT-20K07207
[Book] 翻訳後修飾のプロテオミクス3章翻訳後修飾解析のための試料調整3.2.組織薄切片からの試料調整2011
- Author(s)
  秋本和憲、永坂恵子、岡山明子、川上隆雄
- Publisher
  講談社サイエンティフィク
- Data Source
  KAKENHI-PROJECT-21390443
[Book] 6章翻訳後修飾の機能解析の方法6.8遺伝子操作マウスを用いた個体レベルでの機能解析2011
- Author(s)
  秋本和憲、大野茂男
- Publisher
  講談社サイエンティフィク翻訳後修飾のプロテオミクス
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] Transcriptomic and Functional Evidence Show Similarities between Human Amniotic Epithelial Stem Cells and Keratinocytes2022
- Author(s)
  Li-Ping Liu, Dong-Xu Zheng, Zheng-Fang Xu, Hu-Cheng Zhou, Yun-Cong Wang, Hang Zhou, Jian-Yun Ge, Daisuke Sako, Mi Li, Kazunori Akimoto, Yu-Mei Li, and Yun-Wen Zheng
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 1 Pages: 70-70
- DOI
  10.3390/cells11010070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07207
[Journal Article] High SLC20A1 Expression Is Associated With Poor Prognoses in Claudin-low and Basal-like Breast Cancers2021
- Author(s)
  ONAGA CHOTARO、TAMORI SHOMA、MOTOMURA HITOMI、OZAKI AYAKA、MATSUDA CHIKA、MATSUOKA IZUMI、FUJITA TAKUMA、NOZAKI YUKA、HARA YASUSHI、KAWANO YOHEI、HARADA YOHSUKE、SATO TSUGUMICHI、MANO YASUNARI、SATO KEIKO、AKIMOTO KAZUNORI
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 1 Pages: 43-54
- DOI
  10.21873/anticanres.14750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-20J11980
[Journal Article] Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer.2021
- Author(s)
  Motomura H, Ozaki A, Tamori S, Onaga C, Nozaki Y, Waki Y, Takasawa R, Yoshizawa K, Mano Y, Sato T, Sasaki K, Ishiguro H, Miyagi Y, Nagashima Y, Yamamoto K, Sato K, Hanawa T, Tanuma SI, Ohno S, Akimoto K
- Journal Title
  
  Oncol Lett.
  
  Volume: 22 Issue: 1 Pages: 547-547
- DOI
  10.3892/ol.2021.12808
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05737, KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-21K06914
[Journal Article] GLO 1 and PKCλ Regulate ALDH1-positive Breast Cancer Stem Cell Survival.2021
- Author(s)
  Motomura H, Tamori S, Yatani MA, Namiki A, Onaga C, Ozaki A, Takasawa R, Mano Y, Sato T, Hara Y, Sato K, Xiong Y, Harada Y, Hanawa T, Tanuma SI, Sasaki K, Ohno S, Akimoto K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 41 Issue: 12 Pages: 5959-5971
- DOI
  10.21873/anticanres.15415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05737, KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-21K20732
[Journal Article] Five Genes Associated With Survival in Patients With Lower-grade Gliomas Were Identified by Information-theoretical Analysis2020
- Author(s)
  SATO KEIKO、TAHATA KOUJI、AKIMOTO KAZUNORI
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 5 Pages: 2777-2785
- DOI
  10.21873/anticanres.14250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07207
[Journal Article] High PKCλ expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients2020
- Author(s)
  Nozaki Yuka、Motomura Hitomi、Tamori Shoma、Kimura Yumiko、Onaga Chotaro、Kanai Shotaro、Ishihara Yuka、Ozaki Ayaka、Hara Yasushi、Harada Yohsuke、Mano Yasunari、Sato Tsugumichi、Sato Keiko、Sasaki Kazunori、Ishiguro Hitoshi、Ohno Shigeo、Akimoto Kazunori
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 7 Pages: e0235747-e0235747
- DOI
  10.1371/journal.pone.0235747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-20J11980
[Journal Article] Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line2020
- Author(s)
  Kobayashi Masaki、Ishizaki Yuka、Owaki Mika、Matsumoto Yoko、Kakiyama Yuri、Hoshino Shunsuke、Tagawa Ryoma、Sudo Yuka、Okita Naoyuki、Akimoto Kazunori、Higami Yoshikazu
- Journal Title
  
  Oncotarget
  
  Volume: 11 Issue: 18 Pages: 1653-1665
- DOI
  10.18632/oncotarget.27581
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11119, KAKENHI-PROJECT-20K07207, KAKENHI-PROJECT-20K19686
[Journal Article] Aberrant Expression of the Cell Polarity Regulator aPKCλ/ι is Associated With Disease Progression in Cer2016
- Author(s)
  Mizushima T, Asai-Sato M, Akimoto K, Nagashima Y, Taguri M, Sasaki K, Nakaya MA, Asano R, Tokinaga A, Kiyono T, Hirahara F, Ohno S, Miyagi E.
- Journal Title
  
  Int J Gynecol Pathol.
  
  Volume: 35 Issue: 2 Pages: 106-17
- DOI
  10.1097/pgp.0000000000000228
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08138, KAKENHI-PROJECT-15K10725, KAKENHI-PROJECT-26460456, KAKENHI-PROJECT-24590237, KAKENHI-PROJECT-25462602, KAKENHI-PROJECT-16K19041
[Journal Article] Atypical protein kinase C isoform, aPKCλ, is Essential for Maintaining Hair Follicle Stem Cell Quiescence2015
- Author(s)
  Shin-Ichi Osada, Naoko Minematsu, Fumino Oda, Kazunori Akimoto, Seiji Kawana and Shigeo Ohno
- Journal Title
  
  J Invest Dermatol
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591669
[Journal Article] Colorectal laterally spreading tumors show characteristic expression of cell polarity factors, including atypical protein kinase C λ/ι, E-cadherin, beta-catenin and basement membrane component.2014
- Author(s)
  chikawa Y, Nagashima Y, Morioka K, Akimoto K, Kojima Y, Ishikawa T, Goto A, Kobayashi N, Watanabe K, Ota M, Fujii S, Kawamata M, Takagawa R, Kunizaki C, Takahashi H, Nakajima A, Maeda S, Shimada H, Inayama Y, Ohno S, Endo I.
- Journal Title
  
  Oncol Lett
  
  Volume: 8 Pages: 977-984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460456
[Journal Article] Proteomic analysis of proteins related to prognosis of lung adenocarcinoma.2014
- Author(s)
  Okayama A, Miyagi Y, Oshita F, Nishi M, Nakamura Y, Nagashima Y, Akimoto K, Ryo A, Hirano H.
- Journal Title
  
  J Proteome Res
  
  Volume: 13 Issue: 11 Pages: 4686-464
- DOI
  10.1021/pr4012969
- NAID
  130005454677
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460456, KAKENHI-PROJECT-221S0001
[Journal Article] aPKClambda/iota is a beneficial prognostic marker for pancreatic neoplasms.2013
- Author(s)
  Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kubota K, Kobayashi N, Hosono K, Watanabe S, Sekino Y, Sato T, Sasaki K, Nakaigawa N, Kubota Y, Inayama Y, Endo I, Ohno S, Maeda S, Nakajima A
- Journal Title
  
  Pancreatology
  
  Volume: 13 Issue: 4 Pages: 360-8
- DOI
  10.1016/j.pan.2013.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23590429, KAKENHI-PROJECT-24790714
[Journal Article] High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis2013
- Author(s)
  Y. Yoshihama, Y. Izumisawa, K. Akimoto, Y. Satoh, T. Mizushima, K. Satoh, K. Chida, R. Takagawa, H. Akiyama, Y. Ichikawa, C. Kunisaki, Y. Inayama, I. Endo, Y. Nagashima and S. Ohno
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Issue: 2 Pages: 259-65
- DOI
  10.1111/cas.12066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PLANNED-23112003, KAKENHI-PROJECT-23590429
[Journal Article] The co-expression of aPKCλ/ιand IL-6 in prostate cancer tissue correlates with biochemical recurrence.2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J-y, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Cancer Sci
  
  Volume: 102(8) Pages: 1576-1581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590429
[Journal Article] The co-expression of aPKCλ/ιand IL-6 in prostate cancer tissue correlates with biochemical recurrence2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano JY, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Cancer Science
  
  Volume: 102(8) Pages: 1576-81
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y and Uemura H
- Journal Title
  
  Cancer Science
  
  Volume: 102 Issue: 8 Pages: 1576-1581
- DOI
  10.1111/j.1349-7006.2011.01972.x
- NAID
  10030242512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030, KAKENHI-PROJECT-23590429, KAKENHI-PROJECT-23791798
[Journal Article] The co-expression of aPKCλ/ιand IL-6 in prostate cancer tissue correlates with biochemical recurrence2011
- Author(s)
  Ishiguro H, Akimoto K, et al.
- Journal Title
  
  Cancer Science
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570138
[Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Cancer Science
  
  Volume: 102(8) Pages: 1576-1581
- NAID
  10030242512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247030
[Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano JY, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Cancer Science
  
  Volume: (In press)
- NAID
  10030242512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence2011
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J-y, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Cancer Sci
  
  Volume: 102(8) Pages: 1576-1581
- NAID
  10030242512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] High expression of the atypical protein kinase C λ/ι in gastric cancer is promising prognostic factor for recurrence.2010
- Author(s)
  Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Endo I, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Nagashima Y, Ohno S
- Journal Title
  
  Ann Surg Oncol 17(1)
  
  Pages: 81-88
- Data Source
  KAKENHI-PROJECT-20590368
[Journal Article] High expression of atypical protein kinase C l/I in gastric cancer as a prognositic factor for recurrence2010
- Author(s)
  Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Endo I, Nagashima Y, Ohno S
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 17(1) Pages: 81-88
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] High Expression of Atypical Protein Kinase C λ/.in Gastric Cancer as a Prognostic Factor for Recurrence2010
- Author(s)
  Takagawa R., Akimoto K.(全12名中2番目), Ishiguro H. (全12名中7番目), Nagashima Y. (全12名中11番目)
- Journal Title
  
  Ann Surg Oncol 17
  
  Pages: 81-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570138
[Journal Article] A cell polarity protein aPKC1ambda is required for eye lens formation and growth.2009
- Author(s)
  Sugiyama Y, Akimoto K, Robinson M.L, Ohno S, Qinlan R.A
- Journal Title
  
  Dev Biol 336(2)
  
  Pages: 246-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] A cell polarity protein aPKClambda is required for eye lens formation and growth.2009
- Author(s)
  Sugiyama Y, Akimoto K, Robinson M L, Ohno S, Quinlan R A
- Journal Title
  
  Dev Biol 336(2)
  
  Pages: 246-256
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Proc Natl Acad Sci USA 106(38)
  
  Pages: 16369-16374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] A cell polarity protein aPKClambda is required for eye lens formation and growth2009
- Author(s)
  Sugiyama Y, Akimoto K, et al.
- Journal Title
  
  Developmental Biology 336(2)
  
  Pages: 246-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Proc Natl Acad Sci U S A 106(38)
  
  Pages: 16369-16374
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] A cell polarity protein aPKC lambda is required for eye lens formation and growth2009
- Author(s)
  Sugiyama Y., Akimoto K., Robinson M. L., Ohno S., Quinlan R.
- Journal Title
  
  A.Dev Biol 336
  
  Pages: 246-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570138
[Journal Article] A cell polarity protein aPKClambda is required for eye lens formation and growth2009
- Author(s)
  Sugiyama Y, Akimoto K, Robinson M. L, Ohno S, Quinlan R. A
- Journal Title
  
  Dev Biol
  
  Volume: 336(2) Pages: 246-256
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.2009
- Author(s)
  Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Journal Title
  
  PLoS ONE 4(1)
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] aPKCλ/ι promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.2009
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki T, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Pro Natl Acad Sci USA 106(38)
  
  Pages: 16369-16374
- Data Source
  KAKENHI-PROJECT-20590368
[Journal Article] The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors.2009
- Author(s)
  Kojima Y, Akimoto K, Nagashima Y, Ishiguro H(その他11名)
- Journal Title
  
  Hum Pathol 39
  
  Pages: 824-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570138
[Journal Article] aPKCλ/. promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-62009
- Author(s)
  Ishiguro H., Akimoto K., Nagashima Y.,(その他7名)
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 106
  
  Pages: 16369-16374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570138
[Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms2009
- Author(s)
  Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Journal Title
  
  PLoS ONE
  
  Volume: 4(1)
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] High expression of atypical protein kinase C lambda/iota in gastric cancer as aprognostic factor for recurrence.2009
- Author(s)
  Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Endo I, Ngashima Y, Ohno S
- Journal Title
  
  Ann Surg Oncol 17(1)
  
  Pages: 81-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms2009
- Author(s)
  Hirose T, Satoh D, KuriharaH, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Journal Title
  
  PLoS ONE 4(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An essential role of the universal polarity protein, aPKC1ambda, on the maintenance of podocyte slit diaphragms.2009
- Author(s)
  Hirose T, Satoh D, Kurihara H, Kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Journal Title
  
  PLoS ONE 4(1)
  
  Pages: 4194-4194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms.2009
- Author(s)
  Hirose T, Akimoto K(全10名中6番目)
- Journal Title
  
  PLoS ONE 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570138
[Journal Article] High expression of atypical protein kinase C lambda/iota in gastric cancer as a prognostic factor for recurrence.2009
- Author(s)
  Takagawa R, Akimoto K, Ichikawa Y, Akiyama H, Kojima Y, Ishiguro H, Inayama Y, Aoki I, Kunisaki C, Endo I, Nagashima Y, Ohno S
- Journal Title
  
  Ann Surg Oncol 17(1)
  
  Pages: 81-88
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] PKCλ/ιpromotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-62009
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Sasaki Y, Ishiguro-Imagawa Y, Nakaigawa N, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Proceedings of the National Academy of Sciences(PNAS)
  
  Volume: 106(38) Pages: 16369-16374
- Data Source
  KAKENHI-PROJECT-21390443
[Journal Article] The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors2008
- Author(s)
  Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Ichikawa T, Sasaki T, Kubota Y, InayamaY, Aoki I, Ohno S, Shimada H
- Journal Title
  
  Hum Pathol 39(6)
  
  Pages: 824-831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Collecting duct carcinoma of the kidney : an immunohistochemical evaluation of the use of antibodies for differential diagnosis.2008
- Author(s)
  Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Kobayashi N, Matsuzaki O, Shirai S, Aoki I, Yao M, Shima H
- Journal Title
  
  Hum Pathol 39(9)
  
  Pages: 1350-1359
- Data Source
  KAKENHI-PROJECT-20590368
[Journal Article] The over- expression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors.2008
- Author(s)
  Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Ishikawa T, Sasaki T, Kubota Y, Inayama Y, Aoki I, Ohno S, Shimada H
- Journal Title
  
  Hum Pathol 39(6)
  
  Pages: 824-831
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Inactivation of aPKC λ results in a loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.2006
- Author(s)
  Imai F, Hirai S-I, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S
- Journal Title
  
  Development 133(9)
  
  Pages: 1735-1744
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Inactivation of aPKCλresults in a loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex.2006
- Author(s)
  Imai F, Hirai S-I, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S
- Journal Title
  
  Development 133(9)
  
  Pages: 1735-1744
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains.2006
- Author(s)
  Hirose T, Karasawa M, Sugitani Y, Fujisawa M, Akimoto K, Ohno S, Noda T
- Journal Title
  
  Development 133(7)
  
  Pages: 1389-1398
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Function of aPKClambda in differentiating photoreceptors is required for proper lamination of mouse retina.2005
- Author(s)
  Koike C, Nishida A, Akimoto K, Nakaya M-A, Noda T, Ohno S, Furukawa T
- Journal Title
  
  J.Neurosci. 25(44)
  
  Pages: 10290-10298
- Data Source
  KAKENHI-PROJECT-17014076
[Journal Article] Protein Kinase Cl/i (PKCl/i): A PKC isotype essential for the development of multicellular organisms2003
- Author(s)
  Suzuki, A., Akimoto, K., Ohno, S.
- Journal Title
  
  J. Biochemistry 133
  
  Pages: 9-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] Protein kinase C 1/I (PKC 1/I): aPKC isotype essential for the development of multicellular organism.2003
- Author(s)
  Suzuki A, Akimoto K, Ohno S
- Journal Title
  
  J.Biochem (Tokyo) 133(1)
  
  Pages: 9-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209013
[Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J-y, Takagawa R, Fujinami K, Sasaki K, Aoki I, Ohno S, Kubota Y, Uemura H
- Journal Title
  
  Cancer Sci in press
- NAID
  10030242512
- Data Source
  KAKENHI-PROJECT-20590368
[Journal Article] The co-expression of aPKCλ/ι and IL-6 in prostate cancer tissue correlates with biochemical recurrence.
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y(その他10名)
- Journal Title
  
  Cancer Sci in press
- NAID
  10030242512
- Data Source
  KAKENHI-PROJECT-20570138
[Journal Article] The overexpression and altered localization of the atypical Protein Kinase C lambda/iota in breast cancer correlates with the pathological type of these tumors
- Author(s)
  Kojima Y, Akimoto K, Nagashima Y, Ishiguro H, Shirai S, Chishima T, Ichikawa Y, Insiakama T, Sasaki T, Knbota Y, Knbota Y, Inayama Y, Aoki I, Ohno S, Shimada H
- Journal Title
  
  Human Pathology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014076
[Patent] 初期乳癌の検出方法2011
- Inventor(s)
  秋本和憲、川崎博史、平野久、大野茂男、長嶋洋治
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Industrial Property Number
  2011-044047
- Filing Date
  2011-03-01
- Data Source
  KAKENHI-PROJECT-20570138
[Patent] 初期乳がんモデル用動物2009
- Inventor(s)
  秋本和憲、大野茂男
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Industrial Property Number
  2009-145675
- Filing Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-20570138
[Patent] 初期乳がんモデル用動物2009
- Inventor(s)
  秋本和憲, 大野茂男
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Industrial Property Number
  2009-145675
- Filing Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-20570138
[Patent] 初期乳がんモデル用動物2009
- Inventor(s)
  秋本和憲、大野茂男
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Filing Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-17014076
[Patent] 初期乳がんモデル用動物2007
- Inventor(s)
  秋本和憲、野田哲生、大野茂男
- Industrial Property Rights Holder
  横浜市立大学
- Industrial Property Number
  2007-167036
- Filing Date
  2007-06-25
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] 乳がん由来細胞株の浸潤能とグリコサミノグリカン構造および関連タンパク質との相関関係2024
- Author(s)
  勝本祥央、宮嶋倫、米野雅大、渡辺怜央、多森翔馬、秋本和憲、東伸昭、戸井田敏彦、東恭平
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06139
[Presentation] オーラノフィンはヘパラナーゼ生合成を阻害することで乳がん細胞株の浸潤を抑制する2024
- Author(s)
  宮嶋倫、宮下佳那美、米野雅大、三輪有由奈、多森翔馬、小谷仁司、寺島裕也、秋本和憲、東伸昭、須田貴司、東恭平
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06139
[Presentation] ヘパラナーゼ遺伝子の発現を抑制する既存薬の同定2023
- Author(s)
  宮嶋倫、宮下佳那美、米野雅大、三輪有由奈、多森翔馬、小谷仁司、秋本和憲、東伸昭、須田貴司、東恭平
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K06139
[Presentation] がんゲノミクスデータ解析を起点とした無機リン酸共輸送体SLC20A1のALDH1陽性膵臓がん幹細胞における役割解析2022
- Author(s)
  松岡泉、翁長朝太郎、多森翔馬、石井雅貴、佐藤圭子、佐々木和教、大野茂男、秋本和憲
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] p62とALDH1A3遺伝子共高発現Luminal B型乳癌は予後不良である2022
- Author(s)
  尾崎綾栞、多森翔馬、本村瞳、翁長朝太郎、長島佑夏、小鳥真歩、松田あかり、望月菜々子、佐々木和教、大野茂男、秋本和憲
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] がんゲノミクスデータ解析によるProtein Kinase C ζ（PKCζ）の乳がん幹細胞における役割の解析2022
- Author(s)
  長島佑夏、多森翔馬、本村瞳、尾﨑綾栞、翁長朝太郎、佐々木和教、大野茂男、秋本和憲
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] Glyoxalase 1 and protein kinase Cl as potential therapeutic targets for late-stage breast cancer2021
- Author(s)
  Motomura H., Ozaki A., Tamori S., Onaga C., Nozaki Y., Akimoto K.
- Organizer
  International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] High SLC20A1 expression is associated with poor prognosis in claudin-low and basal-like breast cancers2021
- Author(s)
  Onaga C., Tamori S., Motomura H., Ozaki A., Matsuda C., Matsuoka I., Fujita T., Nozaki Y., Hara Y., Kawano Y., Harada Y., Sato T., Mano Y., Sato K., Akimoto K.
- Organizer
  International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] High PKCλ expression is required for asymmetric cell division of ALDH1-positive cancer stem cells and indicates poor clinical outcome in late-stage breast cancer patients2021
- Author(s)
  Tamori S., Nozaki Y., Motomura H., Onaga C., Ozaki A., Sasaki K., Ohno S., Akimoto K.
- Organizer
  International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer2021
- Author(s)
  Hitomi Motomura-Shiina*, Ayaka Ozaki, Shoma Tamori, Chotaro Onaga, Yuka Nozaki and Kazunori Akimoto
- Organizer
  7TH EDITION - WEBINAR ON BREAST CANCER
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] High p62 and ALDH1A3 expressions are associated with poor prognosis in luminal B breast cancer2021
- Author(s)
  Ozaki A., Motomura H., Tamori S., Onaga C., Matsuda C., Matsuda A., Mochizuki N., Sasaki K., Ohno S., Akimoto K.
- Organizer
  International Research Network Initiative (IRNI) & International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] Claudin-low型、Basal-like型乳がんにおけるSLC20A1高発現は乳がん患者の予後不良に関与する High SLC20A1 Expression is Associated with Poor Prognoses in Claudin-low and Basal-like Breast Cancers2021
- Author(s)
  翁長朝太郎、多森翔馬、本村瞳、尾﨑綾栞、松田千佳、松岡泉、藤田拓真、野崎優香、原泰志、河野洋平、原田陽介、佐藤嗣道、真野泰成、佐藤圭子、秋本和憲
- Organizer
  第141回　日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] TNBC型乳癌においてPKCλとGATA4のタンパク質発現は逆相関し、PKCλタンパク質高発現かつGATA4タンパク質低発現患者は予後不良である Inverse correlation between PKCλ and GATA4 at protein level indicates poorer clinical outcomes in TNBC patients2021
- Author(s)
  尾崎綾栞、多森翔馬、今岡宏太朗、山口淳三、樋上賀一、秋本和憲
- Organizer
  第141回　日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] PKCλ高発現はALDH1A3陽性乳癌幹細胞の非対称分裂能に関与する High PKCλ expression is required for asymmetric cell division of ALDH1A3-positive breast cancer stem cell2021
- Author(s)
  多森翔馬、野崎優香、本村瞳、翁長朝太郎、尾﨑綾栞、佐々木和教、大野茂男、秋本和憲
- Organizer
  第141回　日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] ステージIII-IV乳癌におけるGLO 1 - PKCλ共発現患者は予後不良である Correlation between Glyoxalase 1 and Protein kinase C λ is predictive of poor clinical outcomes in late-stage breast cancer2021
- Author(s)
  本村瞳、尾﨑綾栞、多森翔馬、翁長朝太郎、野崎優香、和氣由布子、高澤涼子、吉澤一巳、真野泰成、佐藤嗣道、佐々木和教、石黒斉、宮城洋平、長嶋洋治、山本紘司、佐藤圭子、花輪剛久、田沼靖一、大野茂男、秋本和憲
- Organizer
  第141回　日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] Glyoxalase 1 and protein kinase Cλ as potential therapeutic targets for late-stage breast cancer2021
- Author(s)
  本村瞳、尾崎綾栞、多森翔馬、野崎優香、高澤涼子、佐々木和教、石黒斉、宮城洋平、長嶋洋治、田沼靖一、大野茂男、秋本和憲
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] ステージⅢ-Ⅳ乳癌におけるc-Met, PKC λ , ALDH1A3共発現患者は予後不良である2020
- Author(s)
  本村瞳、野崎優香、翁長朝太郎、尾﨑綾栞、多森翔馬、秋本和憲
- Organizer
  第６４回　日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] TNBC型乳癌におけるPKC λ とGATA4の免疫組織学的解析2020
- Author(s)
  尾崎綾栞、多森翔馬、今岡宏太朗、山口淳三、樋上賀一、秋本和憲
- Organizer
  第６４回　日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] Correlation between Glyoxalase 1 and PKCλ is predictive of poor clinical outcomes in late-stage breast cancer ステージIII-IV乳癌におけるGLO 1 - PKCλ共発現患者は予後不良である2020
- Author(s)
  本村瞳、尾崎綾栞、多森翔馬、野崎優香、高澤涼子、佐々木和教、石黒斉、宮城洋平、長嶋洋治、田沼靖一、大野茂男、秋本和憲
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] 乳がんゲノムデータベースを用いたSLC20A1遺伝子発現と予後の検討2020
- Author(s)
  翁長朝太郎、多森翔馬、本村瞳、藤田拓真、真野泰成、佐藤嗣道、田畑耕司、佐藤圭子、秋本和憲
- Organizer
  第６４回　日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-20K07207
[Presentation] ヒト乳癌におけるAtypical protein kinase C (aPKC)λ/ιと糖代謝機構との関連2016
- Author(s)
  本村瞳,　片山鈴花,　多森翔馬,　松村将史,　柳川拓哉,　和氣由布子,　高澤涼子,　田沼靖一,　宮城洋平,　長嶋洋治,　今井美沙,　佐藤圭子,　秋本和憲
- Organizer
  第136回日本薬学会年会
- Place of Presentation
  パシフィコ横浜(横浜市西区)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26460456
[Presentation] 細胞極性因子aPKCλは毛包幹細胞の維持に必要である2014
- Author(s)
  長田真一，峰松直子，小田文乃，秋本和憲，川名誠司，眞鍋　求，大野茂男
- Organizer
  第22回毛髪科学研究会
- Place of Presentation
  東京
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-24591669
[Presentation] The Roles of aPKCλin Maintaining Epidermal Homeostasis2014
- Author(s)
  長田真一，峰松直子，小田文乃，秋本和憲，川名誠司，眞鍋　求，大野茂男
- Organizer
  第38回表皮細胞研究会
- Place of Presentation
  鹿児島
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24591669
[Presentation] The nuclear localization and overexpression of atypical protein kinase C in cervical cancer correlate with prognosis2012
- Author(s)
  水島大一, 秋本和憲, 長嶋洋治, 最上多恵, 佐藤美紀子, 宮城悦子, 亀田陽一, 稲山嘉明, 大橋健一, 青木一郎, 大野茂男, 平原史樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  北海道,札幌市,ロイトン札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] 細胞極性制御因子aPKCによる乳腺上皮前駆細胞の増殖制御と乳がんにおけるその破綻2012
- Author(s)
  秋本和憲, 長嶋洋治, 石黒斉, 鄭允文, 佐々木和教, 谷口英樹, 野田哲生, 大野茂男
- Organizer
  第30回日本ヒト細胞学会学術集会シンポジウム
- Place of Presentation
  大阪府,大阪市,梅田スカイビル
- Year and Date
  2012-08-19
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] 細胞極性制御因子aPKCによる乳腺上皮前駆細胞の増殖制御と乳がんにおけるその破綻.2012
- Author(s)
  秋本和憲, 長嶋洋治, 石黒　斉, 鄭　允文, 佐々木和教, 谷口英樹, 野田哲生, 大野茂男
- Organizer
  第３０回日本ヒト細胞学会学術集会シンポジウム
- Place of Presentation
  梅田スカイビル(大阪府）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Prognostic impact of aPKCλ/ιexpression in pancreatic cancer2011
- Author(s)
  加藤真吾, 秋本和憲, 長嶋洋治, 石黒斉, 古林規敏, 前田慎, 大野茂男, 中島淳
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  愛知県,名古屋市,名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] aPKCλ/ιregulates mammary luminal progenitor cell propagation and its disruption in a subpopulation of breast cancer2011
- Author(s)
  秋本和憲, 長嶋洋治, 石黒斉, 鄭允文, 佐々木和教, 小島康幸, 谷口英樹, 大野茂男, 野田哲生
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  愛知県,名古屋市,名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] In laterally spreading type tumors (LSTs) of the colon or the rectum, expression of the atypical protein kinase C lambda/iota is correlated to expression of beta-catenin and type IV collagen.2011
- Author(s)
  Ichikawa Y, Ishikawa T, Shimizu D, Goto A, Shimamura T, Suwa H, Tatsumi K, Watanabe K, Ota M, Fujii S, Kawamata M, Akimoto K, Nagashima Y, Takahashi H, Nakajima A, Ohno S, Endo I
- Organizer
  The 102nd Annual Meeting of American Assiciation for Cancer Research,
- Place of Presentation
  Orange County Convention Center, Orland, Florida, USA
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] aPKCλ/ι regulates mammary luminal progenitor cell propagation and its disruption in a subpopulation of breast cancer.2011
- Author(s)
  秋本和憲、長嶋洋治，石黒斉，鄭允文，佐々木和教，小島康幸，谷口英樹、大野茂男、野田哲生
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知）
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] 口腔扁平上皮癌におけるaPKCλ/ι過剰発現の臨床病理学的意義2011
- Author(s)
  馬場隼一，秋本和憲，長嶋洋治，石黒　斉，來生　知，光藤健司，稲山嘉明，青木一郎，大野茂男，藤内　祝
- Organizer
  第35回日本頭頸部癌学会
- Place of Presentation
  ウインクあいち（愛知県）
- Data Source
  KAKENHI-PROJECT-23592972
[Presentation] Prognostic impact of aPKCλ/ι expression in pancreatic cancer.2011
- Author(s)
  加藤真吾，秋本和憲，長嶋洋治，石黒斉，古林規敏，前田慎，大野茂男，中島淳
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知）
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] Atypical protein kinase Cλ/ιregulates mouse mammary progenitor cell propagation2010
- Author(s)
  Akimoto K, Zheng Y-W, Nagashima Y, Ishiguro H, Asai-Sato M, Kojima Y, Li B, Sasaki K, Kagawa E, Kim M, Taniguchi H, Noda T, and Ohno S
- Organizer
  6th International Symposium on Hormonal Oncogenesis
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-21390443
[Presentation] 細胞極性因子aPKCλによる上皮前駆細胞の増殖制御とその破綻2010
- Author(s)
  秋本和憲, 他
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] In laterally spreading type tumors(LSTs) of the colon or the rectum, expression of the atypical protein kinase C lambda/iota is correlated to expression of beta-catenin and type IV collagen2010
- Author(s)
  Ichikawa Y, Ishikawa T, Shimizu D, Goto A, Shimamura T, Suwa H, Tatsumi K, Watanabe K, Ota M, Fujii S, Kawamata M, Akimoto K, Nagashima Y, Takahashi H, Nakajima A, Ohno S, Endo I
- Organizer
  The 102nd Annual Meeting of American Assiciation for Cancer Research,(Orland, FL)
- Place of Presentation
  Orland, FL
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21390443
[Presentation] aPKC and IL-6 expression in prostate cancer tissues.2010
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kagawa E, Sasaki T, Sano J, Takagawa R, Sasaki K, Fujinami K, Aoki I, Ohno S, Kubota Y, Uemura H
- Organizer
  The 69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka International Convention Center
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性によるHippo経路の抑制がマウス着床前胚における位置依存的な細胞分化をつかさどる2010
- Author(s)
  平手良和, 平原志乃, 井上健一, 中尾和貴, 鈴木厚, 秋本和憲, 大野茂男, 平井孝明, 千田和広, Marikawa Y, Vernadeth A, 佐々木洋
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(ポスター発表)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] aPKC and IL-6 expression in prostate cancer tissues.2010
- Author(s)
  Ishiguro H, Akimoto K, et al.
- Organizer
  The 69th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka Osaka International Convention Center
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20570138
[Presentation] aPKC and IL-6 expression in prostate cancer tissues.2010
- Author(s)
  石黒斉, 秋本和憲, 長嶋洋治, 加川絵理子, 佐々木毅, 佐野仁勇, 高川亮, 佐々木和教, 藤浪潔, 青木一郎, 大野茂男, 窪田吉信, 上村博司
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] 細胞極性制御因子aPKCλによる上皮前駆細胞の増殖制御とその破綻2010
- Author(s)
  秋本和憲, 鄭允文, 長嶋洋治, 石黒斉, 佐々木和教, 金民大, 李斌, 角和卓, 谷口英樹, 野田哲生, 大野茂男
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] 細胞極性制御因子aPKC λによる上皮前駆細胞の増殖制御とその破綻2010
- Author(s)
  秋本和憲, ら
- Organizer
  第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫県神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20570138
[Presentation] 細胞極性制御因子 aPKCλによる上皮前駆細胞の増殖制御とその破綻2010
- Author(s)
  秋本和憲, ら
- Organizer
  第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫県神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20570138
[Presentation] 細胞極性因子aPKCλによる上皮前駆細胞の増殖制御とその破綻2010
- Author(s)
  秋本和憲, 鄭允文, 長嶋洋治, 石黒斉, 佐々木和教, 金民大, 李文武, 角和卓, 谷口英樹, 野田哲生, 大野茂男
- Organizer
  第33回日本分子生物学会・第83回日本生化学会合同大会ワークショップ「上皮細胞の機能とその破綻がもたらす病態のメカニズム」
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] Atypical Protein Kinase Cλ Regulates Mouse Mammary Progenitor Cell Propagation.2010
- Author(s)
  秋本和憲
- Organizer
  Sixth International Symposium on Hormonal Oncogenesis
- Place of Presentation
  Chiba SHERATON GRANDE TOKYO BAY HOTEL
- Year and Date
  2010-09-14
- Data Source
  KAKENHI-PROJECT-20570138
[Presentation] 細胞極性によるHippo経路の抑制がマウス着床前胚における位置依存的な細胞分化をつかさどる2010
- Author(s)
  平手良和, 平原志乃, 井上健一, 中尾和貴, 鈴木厚, 秋本和憲, 大野茂男, 平井孝明, 千田和広, Marikawa Y, Vernadeth A, 佐々木洋
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(口頭発表)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] Atypical protein kinase Cλ/ι regulates mouse mammary progenitor cell propagation.2010
- Author(s)
  Akimoto K, Zheng Y-W, Nagashima Y, Ishiguro H, Asai-Sato M, Kojima Y, Li B, Sasaki K, Kagawa E, Kim M, Taniguchi H, Noda T, Ohno S
- Organizer
  6th International Symposium on Hormonal Oncogenesis
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] Atypical protein kinase Cλ/ιregulates mouse mammary progenitor cell propagation.2010
- Author(s)
  Akimoto K, et.al.
- Organizer
  6th International Symposium on Hormonal Oncogenesis
- Place of Presentation
  シェラトン・グランデ・トーキョーベイ・ホテル(千葉)
- Year and Date
  2010-09-12
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] Atypical protein kinase Cλ/ιregulates mouse mammary progenitor cell propagation.2010
- Author(s)
  Akimoto K, Zheng Y-W, Nagashima Y, Ishiguro H, Asai-Sato M, Kim M, Taniguchi H, Noda T, Ohno S., et al.
- Organizer
  6th International Symposium on Hormonal Oncogenesis
- Place of Presentation
  千葉県浦安市, シェラトン・グランデ・トーキョーベイホテル
- Year and Date
  2010-09-13
- Data Source
  KAKENHI-PROJECT-21390443
[Presentation] Clinical significance of typical protein kinase iota expression in gastric cancer.2009
- Author(s)
  Takagawa R, Nagashima Y, Akimoto K, Akiyama H, Ono H, Kimura J, Ichikawa Y, Endo I
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] The overexpression of the atypical protein kinase C λ/ι in malignant melanoma correlates with its undifferentiation and metastatic ability.2009
- Author(s)
  Miwa H., Akimoto K., et al.
- Organizer
  The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Hakata, JAL Resort Sea Hawk Hotel Fukuoka
- Data Source
  KAKENHI-PROJECT-20570138
[Presentation] Expression of the atypical protein kinase C in lateral spreading type tumors of the colon or the rectum.2009
- Author(s)
  Ichikawa Y, Kojima Y, Ishikawa T, Shimizu D, Goto A, Hirokawa S, Kijima M, Yamamoto H, Suwa H, Yamagishi S, Osada S, Ota M, Fujii S, Endo I, Shimada H, Akimoto K, Nagashima Y, Ohno S
- Organizer
  100th Annual Meeting of American Association for Cancer Research
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] The overexpression of the atypical protein kinase C λ/ι in malignant melanoma correlates with its undifferentiation state and metastatic ability.2009
- Author(s)
  Miwa H, Akimoto K, Inoue Y, Wada H, Ishiguro H, Ohno S, Nagashima Y, Ikezawa Z
- Organizer
  34th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] Expression of the atypical protein kinase C in lateral spreading type tumors of the colon or the rectum.2009
- Author(s)
  Ichikawa Y, Kojima Y, Nagashima Y, Akimoto K, Ishikawa T, Goto A, Hirokawa S, Yamagishi S, Ota M, Fujii S, Nakajima A, Endo I, Ohno S
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] 前立腺癌におけるaPKCの発現と前立腺癌進展機構2009
- Author(s)
  石黒斉, 秋本和憲, 長嶋洋治, 小島康幸, 佐々木毅, 上村博司, 大野茂男, 窪田吉信
- Organizer
  第97回日本泌尿器科学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] aPKCλ regulates mammary-gland morphogenesis through the transcriptional suppression of ErbB2/HER-2 gene2008
- Author(s)
  秋本和憲
- Organizer
  Second JCA-AACR Special Joint Conference The Latest Advances in Breast Cancer Research
- Place of Presentation
  兵庫県立淡路夢舞台国際会議場
- Year and Date
  2008-07-14
- Data Source
  KAKENHI-PROJECT-20570138
[Presentation] The cell polarity protein aPKCλ plays a critical role in the maintenance of podocyte slit diaphragms2008
- Author(s)
  Hirose T, Satoh D, Kurihara H, Akimoto K, Matsusaka T, Ichikawa I, Noda, T, Ohno S
- Organizer
  The 7th International Podocyte Conference
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The role of aPKC lambda in prostate cancer progression.2008
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Ishiguro Y, Sasaki T, Uenura H, Ohno S, Kubota Y
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590368
[Presentation] Conditional depletion of aPKCλ in eye lens causes microphthalmia and cataract2008
- Author(s)
  Sugiyama Y, Akimoto K, Robinson M. L, Quinlan, R. A, Ohno S
- Organizer
  ARVO (Association for Research in Vision and Ophthalmology) 2008Annual Meeting, 2008
- Place of Presentation
  Florida USA
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The role of aPKC lambda in prostate cancer progression2008
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Ishiguro Y, Sasaki T, Umemura H, Ohno S, Kubota Y
- Organizer
  The 67th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The cell polarity protein, aPKClambda, plays a critical rolein the maintenance of podocyte slit diaphragms, specific type if epithelial intercellular junctions2008
- Author(s)
  Hirose T, Satoh D, Kurihara H, kusaka C, Hirose H, Akimoto K, Matsusaka T, Ichikawa I, Noda T, Ohno S
- Organizer
  BMB2008
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] aPKCλ regulates mammary-gland morphogenesis through the transcriptional suppression of ErbB2/HER-2 gene2008
- Author(s)
  秋本和憲, et al.
- Organizer
  Second JCA-AACR Special Joint Conference The Latest Advances in Breast Cancer Research.
- Place of Presentation
  兵庫県立淡路夢舞台国際会議場
- Year and Date
  2008-07-14
- Data Source
  KAKENHI-PROJECT-20570138
[Presentation] aPKC1 regulates mammary-gland morphogenesis through the transcriptiona 1 suppression of ErbB2/HER-2 gene2008
- Author(s)
  Akimoto K, Nagashima K, Ishiguro H, Kojima Y, Kim M, Sasaki K, Noda T, Ohno S
- Organizer
  Second JCA-AACR Special Joint Conference, The Latest Advances in Breast Cancer Research : From Basic Science to Therapeutics
- Place of Presentation
  Awaji, Hyogo, Japan
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The role of apkcl in breast cancer2007
- Author(s)
  Akimoto K
- Organizer
  Yokohama City University 21st Century COE Program, Cell Polarity 2007-International symposium on CellPolarity Ststem and Future Medicine
- Place of Presentation
  Hayama
- Year and Date
  2007-12-09
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] aPKC role in prostatic cancer progression2007
- Author(s)
  Ishiguro H, Akimoto K, Nagashima Y, Kojima Y, Ishiguro Y, Sasaki T, Uemura H, Ohono S, Kubota Y
- Organizer
  Yokohama City University 21st Century COE Program, Cell Polarity 2007-International symposium on CellPolarity Ststem and Future Medicine
- Place of Presentation
  Hayama
- Year and Date
  2007-12-09
- Data Source
  KAKENHI-PROJECT-17014076
[Presentation] The nuclear localization and overexpression of atypical protein kinase C in cervical cancer correlate with prognosis.
- Author(s)
  水島大一,秋本和憲,長嶋洋治,最上多恵, 佐藤美紀子,宮城悦子,亀田陽一,稲山嘉明,大橋健一,青木一郎,大野茂男,平原史樹
- Organizer
  .第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] 細胞極性制御因子aPKCによる乳腺上皮前駆細胞の増殖制御と乳がんにおけるその破綻.
- Author(s)
  秋本和憲、長嶋洋治、石黒斉、鄭允文、佐々木和教、谷口英樹、野田哲生、大野茂男
- Organizer
  第30回日本ヒト細胞学会学術集会
- Place of Presentation
  梅田スカイビル（大阪府）
- Data Source
  KAKENHI-PROJECT-23590429
[Presentation] A Cell Polarity Protein，aPKCλ，is Essential for Maintaining Hair Follicle Stem Cell Quiescence and Hair Follicle Regeneration
- Author(s)
  長田真一，峰松直子，小田文乃，秋本和憲，川名誠司，大野茂男
- Organizer
  第39回日本研究皮膚科学会年次学術大会
- Place of Presentation
  大阪
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-24591669
[Presentation] aPKClambda regulates mammary luminal progenitor cell propagation and its disruption in a subpopulation of breast cancer.
- Author(s)
  Akimoto K, Nagashima Y, Ishiguro H, Zheng Y W, Osato N, Sasaki K, Kojima Y, Tamura T, Taniguchi H, Noda T, Ohno S
- Organizer
  US-Japan Summer Conference on Cancer, Diabetes and Inflammation
- Place of Presentation
  Beckman Center Lecture Hall（Duarte, CA, USA）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] aPKC λ regulates mammary luminal progenitor cell propagation and it’s disruption in a subpopulation of breast cancer.
- Author(s)
  Akimoto K, Nagashima Y, Ishiguro H, Zheng Y-W, Sasaki K, Kojima Y, Taniguchi H, Ohno S
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] The nuclear localization and overexpression of atypical protein kinase C in cervical cancer correlate with prognosis.
- Author(s)
  Mizushima　T, Akimoto K, Nagashima Y, Mogami T, Sato M, Miyagi E, Kameda Y, Inayama Y, Ohashi K, Aoki I, Ohno S, Hirahara F
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、さっぽろ芸術館、札幌市教育文化会館（北海道）
- Data Source
  KAKENHI-PROJECT-22247030
[Presentation] An Apicobasal Cell Polarity Protein aPKCλ regulates the hair follicle cycling and Hair Follicle Stem Cells Homeostasis
- Author(s)
  Osada S，Minematsu N，Oda F，Akimoto K，Kawana S and Ohno S
- Organizer
  The 44th Annual European Society for Dermatological Research Meeting
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24591669
[Presentation] Prognostic impact of aPKC λ/ι expression in pancreatic cancer.
- Author(s)
  Kato S, Akimoto K, Nagashima Y, Ishiguro H, Kobayashi N, Maeda S, Ohno S, Nakajima A
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-22247030

1. OHNO Shigeo (10142027)

# of Collaborated Projects: 9 results

# of Collaborated Products: 41 results
2. NAGASHIMA Yoji (10217995)

# of Collaborated Projects: 7 results

# of Collaborated Products: 39 results
3. SUZUKI Atsushi (00264606)

# of Collaborated Projects: 7 results

# of Collaborated Products: 4 results
4. HIRAI Syu-ichi (80228759)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
5. MIZUNO Keiko (90221803)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. ISHIGURO Hitoshi (00381666)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
7. UEMURA Hiroji (50244439)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
8. AOKI Ichiro (00184028)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
9. HIROSE Tomonori (20381668)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
10. INAYAMA Yoshiaki (10184730)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. SATO Mikiko (70326049)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. MIZUSHIMA Taichi

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. CHISHIMA Takashi (70438141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ISHIKAWA Takashi (80275049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. KANNO Hiroshi (40244496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NOZAWA Akinori (00228321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KUBOTA Yoshinobu (10106312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
18. KAWASAKI Hiroshi (70169704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. YAMASHITA Akio (20405020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NAKAYA Masa-aki (70422095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. SASAKI Kazunori (50438131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
22. KOIZUMI Toshiyuki (80323575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MITSUDOH Kenji (70303641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. KIOI Mitomu (30545059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. OSADA Shin-Ichi (00244484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
26. UEMURA Hiroji (70254208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. NAKAIGAWA Noboru (00237207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. OHASHI Ken-ichi (40231203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. MARUYAMA Yasuyo (10534141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. MIYAGI Etsuko (40275053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. HIRAHARA Fumiki (30201734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 東恭平 (10463829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
33. 米野雅大 (40866307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
34. TANIGUCHI Tamiyo

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
35. IZUMISAWA Yusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. KATO Shingo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
37. IZUMISAWA Yuhsuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. KAWASHIMA Masato

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 杉山由樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. ICHIKAWA Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. OKITA Naoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 高澤涼子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
43. 來生知

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 樋上賀一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Akimoto Kazunori 秋本 和憲

AKIMOTO Kazunori 秋本 和憲

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Elucidation of a novel regulatory axis of glycolysis in cancer stem cells based on cancer genomics database analysisPrincipal Investigator

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Regulation of Cell polarity by aPKC dependent gene expressionPrincipal Investigator

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細胞極性因子aPKClの哺乳類器官形成及び病態(発がん)における役割の解析Principal Investigator

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Akimoto Kazunori 秋本和憲

AKIMOTO Kazunori 秋本和憲

[Book] 月刊　「Precision Medicine」11月号　リキッドバイオプシーによるゲノム医療情報論・統計解析手法を用いたがんゲノミクスデータ解析による乳がん患者層別化2021