kobayashi masahiko 小林昌彦

… Alternative Names

Kobayashi Masahiko 小林昌彦

KOBAYASHI Masahiko 小林昌彦

小林昌彦コバヤシマサヒコ

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Researcher Number	70285633
Other IDs
External Links
Affiliation (Current)	2025: 金沢大学, がん進展制御研究所, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 金沢大学, がん進展制御研究所, 助教 2013 – 2015: 金沢大学, がん進展制御研究所, 助教 2011: 金沢大学, がん進展制御研究所, 助教 2010: 金沢大学, がん研究所, 助教 2000: 金沢大学, がん研究所, 助手 1999: 岩手医科大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology / Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals / Morphological basic dentistry
Keywords	Principal Investigator 膠芽腫 / glioma / 細胞応答 / 酸化ストレス / ATM / 悪性脳腫瘍 / グリオーマ / 癌 / 神経膠芽腫 / オートファジー … More / mTOR / mTORC1 / 代謝ストレス / 代謝産物 / 老化 / 応答 / 活性酸素 / 突然変異 / リボフラビン / ribA / GTP cyclohydrolase II Less

組織環境を介した可塑性によって規定される治療抵抗性の分子基盤Principal Investigator
- Principal Investigator
  
  小林昌彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Molecular mechanism of subtype shift underlying plasticity and therapy-resistance in glioblastomaPrincipal Investigator
- Principal Investigator
  
  Kobayashi Masahiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Molecular mechanisms regulating energy metabolism and stemness propertyPrincipal Investigator
- Principal Investigator
  
  Kobayashi Masahiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Involvement of DNA damage-independent and ATM-dependent stress response in tumor suppressive mechanismPrincipal Investigator
- Principal Investigator
  
  Kobayashi Masahiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kanazawa University
Activation mechanism and physiological role of the ATM checkpoint kinase in response to oxidative stressPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Masahiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kanazawa University
酸化ストレスに抵抗する細菌ゲノム安定化機構の解析Principal Investigator
- Principal Investigator
  
  小林昌彦
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kanazawa University
  Iwate Medical University

[Journal Article] Therapeutic potential of pentamidine for glioma‐initiating cells and glioma cells through multimodal antitumor effects2023
- Author(s)
  Tamai S, Ichinose T, Jiapaer S, Hirai N, Sabit H, Tanaka S, Kinoshita M, Kobayashi M, Hirao A, Nakada M.
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 7 Pages: 2920-2930
- DOI
  10.1111/cas.15827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-23K06629, KAKENHI-PROJECT-22H00484, KAKENHI-PROJECT-23K27437
[Journal Article] Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation2023
- Author(s)
  Kurayoshi K, Takase Y, Ueno M, Ohta K, Fuse K, Ikeda S, Watanabe T, Nishida Y, Horike SI, Hosomichi K, Ishikawa Y, Tadokoro Y, Kobayashi M, Kasahara A, Jing Y, Shoulkamy MI, Meguro-Horike M, Kojima K, Kiyoi H, Sugiyama H, Nagase H, Tajima A, Hirao A.
- Journal Title
  
  Cell Death Disease
  
  Volume: 14 Issue: 9 Pages: 642-642
- DOI
  10.1038/s41419-023-06168-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18298, KAKENHI-PROJECT-23K14729, KAKENHI-PROJECT-21K08396, KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K08448, KAKENHI-PROJECT-23K06629, KAKENHI-PROJECT-23K06672, KAKENHI-PROJECT-23K07855, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-23K27437, KAKENHI-PROJECT-23K27624
[Journal Article] Therapeutic advantage of targeting lysosomal membrane integrity supported by lysophagy in malignant glioma2022
- Author(s)
  Jing Yongwei、Kobayashi Masahiko、Vu Ha Thi、Kasahara Atsuko、Chen Xi、Pham Loc Thi、Kurayoshi Kenta、Tadokoro Yuko、Ueno Masaya、Todo Tomoki、Nakada Mitsutoshi、Hirao Atsushi
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 8 Pages: 2716-2726
- DOI
  10.1111/cas.15451
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08448, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-22H00483, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K16264
[Journal Article] RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia2022
- Author(s)
  Pham Loc Thi、Peng Hui、Ueno Masaya、Kohno Susumu、Kasada Atuso、Hosomichi Kazuyoshi、Sato Takehiro、Kurayoshi Kenta、Kobayashi Masahiko、Tadokoro Yuko、Kasahara Atsuko、Shoulkamy Mahmoud I.、Xiao Bo、Worley Paul F.、Takahashi Chiaki、Tajima Atsushi、Hirao Atsushi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 621 Pages: 74-79
- DOI
  10.1016/j.bbrc.2022.06.089
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08448, KAKENHI-PUBLICLY-22H05622, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H01356, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-21K19502, KAKENHI-PROJECT-21K16264, KAKENHI-PUBLICLY-21H00342
[Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner2021
- Author(s)
  Nomura Naho、Ito Chiaki、Ooshio Takako、Tadokoro Yuko、Kohno Susumu、Ueno Masaya、Kobayashi Masahiko、Kasahara Atsuko、Takase Yusuke、Kurayoshi Kenta、Si Sha、Takahashi Chiaki、Komatsu Masaaki、Yanagawa Toru、Hirao Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 1666-1679
- DOI
  10.1038/s41598-021-81076-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06657, KAKENHI-PROJECT-19K08860, KAKENHI-PROJECT-20K07566, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-19K22555, KAKENHI-PROJECT-19K17824, KAKENHI-PROJECT-19H03846, KAKENHI-PROJECT-20K07565, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K07558
[Journal Article] Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples2020
- Author(s)
  Masaya Ueno, Takuya Tomita, Hiroshi Arakawa, Takahiro Kakuta, Tada-aki Yamagishi, Jumpei Terakawa, Takiko Daikoku, Shin-ichi Horike, Sha Si, Kenta Kurayoshi, Chiaki Ito, Atsuko Kasahara, Yuko Tadokoro, Masahiko Kobayashi, Tsutomu Fukuwatari, Ikumi Tamai, Atsushi Hirao & Tomoki Ogoshi
- Journal Title
  
  Communications Chemistry
  
  Volume: 3
- NAID
  120006939157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07566
[Journal Article] Identification of 2-Fluoropalmitic Acid as a Potential Therapeutic Agent Against Glioblastoma2020
- Author(s)
  Jiapaer Shabierjiang、Furuta Takuya、Dong Yu、Kitabayashi Tomohiro、Sabit Hemragul、Zhang Jiakang、Zhang Guangtao、Tanaka Shingo、Kobayashi Masahiko、Hirao Atsushi、Nakada Mitsutoshi
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 26 Issue: 36 Pages: 4675-4684
- DOI
  10.2174/1381612826666200429092742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07566, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-18H02910
[Journal Article] Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma2019
- Author(s)
  Kitabayashi Tomohiro、Dong Yu、Furuta Takuya、Sabit Hemragul、Jiapaer Shabierjiang、Zhang Jiakang、Zhang Guangtao、Hayashi Yasuhiko、Kobayashi Masahiko、Domoto Takahiro、Minamoto Toshinari、Hirao Atsushi、Nakada Mitsutoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 10049-10049
- DOI
  10.1038/s41598-019-46454-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-19H01033, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-18H02910, KAKENHI-PROJECT-18K19577
[Journal Article] Distinct roles of Rheb and Raptor in activating mTOR complex 1 for the self-renewal of hematopoietic stem cells2018
- Author(s)
  Hui Peng, Atsuo Kasada, Masaya Ueno, Takayuki Hoshii, Yuko Tadokoro, Naho Nomura, Chiaki Ito, Yusuke Takase, Ha Thi Vu, Masahiko Kobayashi, Bo Xiao, Paul F. Worley, Atsushi Hirao
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 1 Pages: 1129-1135
- DOI
  10.1016/j.bbrc.2017.11.140
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09824, KAKENHI-PROJECT-17K07160, KAKENHI-PROJECT-17K09919, KAKENHI-PROJECT-17K19585, KAKENHI-PUBLICLY-16H01199, KAKENHI-PUBLICLY-17H05638, KAKENHI-PROJECT-15H02361
[Journal Article] Loss of Tsc1 accelerates malignant gliomagenesis when combined with oncogenic signals.2014
- Author(s)
  Yamada D, Hoshii T, Tanaka S, Hegazy AM, Kobayashi M, Tadokoro Y, Ohta K, Ueno M, Ali MAE, Hirao A.
- Journal Title
  
  J Biochem.
  
  Volume: 155 Issue: 4 Pages: 227-33
- DOI
  10.1093/jb/mvt112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25861263, KAKENHI-PROJECT-26460361
[Journal Article] Association of a murine leukaemia stem cell gene signature based on nucleostemin promoter activity with prognosis of acute myeloid leukaemia in patients.2014
- Author(s)
  Ali MA, Naka K, Yoshida A, Fuse K, Kasada A, Hoshii T, Tadokoro Y, Ueno M, Ohta K, Kobayashi M, Takahashi C, Hirao A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 450 Issue: 1 Pages: 837-843
- DOI
  10.1016/j.bbrc.2014.06.066
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24240119, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-26290037, KAKENHI-PROJECT-26460361, KAKENHI-PROJECT-26640070
[Journal Article] ATM mediates pRB function to control DNMT1 protein stability and DNA methylation.2013
- Author(s)
  Shamma A, Suzuki M, Hayashi N, Kobayashi M, Sasaki N, Nishiuchi T, Doki Y, Okamoto T, Kohno S, Muranaka H, Kitajima S, Yamamoto K, Takahashi C
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 33 Issue: 16 Pages: 3113-3124
- DOI
  10.1128/mcb.01597-12
- NAID
  120005312327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340028, KAKENHI-PROJECT-25830076, KAKENHI-PROJECT-25830077
[Journal Article] Regulatory interaction between NBS1 and DNMT1 responding to DNA damage2013
- Author(s)
  Hayashi N, Kobayashi M, Shamma A, Morimura Y, Takahashi C, Yamamoto K
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 154 Issue: 5 Pages: 429-435
- DOI
  10.1093/jb/mvt071
- NAID
  120005373519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340028
[Journal Article] ATR-ATRIP Kinase Complex Triggers Activation of the Fanconi Anemia DNA Repair Pathway2012
- Author(s)
  Tomoko Shigechi, Junya Tomida, Koichi Sato, Masahiko Kobayashi, John K.Eykelenboom, Fabio Pessina, Yanbin Zhang, Emi Uchida, Masamichi Ishiai, Noel F.Lowndes, Kenichi Yamamoto, Hitoshi Kurumizaka, Yoshihiko Maehara, Minoru Takata
- Journal Title
  
  Cancer Research
  
  Volume: 72 Issue: 5 Pages: 1149-1156
- DOI
  10.1158/0008-5472.can-11-2904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02700, KAKENHI-PROJECT-21390094, KAKENHI-PROJECT-22310119, KAKENHI-PROJECT-22710052, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131505, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23651046
[Journal Article] Functional relationship between Claspin and Rad172011
- Author(s)
  Yoshimura, A., Akita, M., Hosono, Y., Abe, T., Kobayashi, M., Yamamoto, K.I., Tada, S., Seki, M., Enomoto, T.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 414 Issue: 2 Pages: 298-303
- DOI
  10.1016/j.bbrc.2011.09.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059, KAKENHI-PROJECT-22710052, KAKENHI-PROJECT-23370065
[Journal Article] Dual Functions of ASCIZ in the DNA Base Damage Response and Pulmonary Organogenesis2010
- Author(s)
  Jurado S, Smyth I, van Denderen B, Tenis N, Hammet A, Hewitt K, Ng JL, McNees CJ, Kozlov SV, Oka H, Kobayashi M, Conlan LA, Cole TJ, Yamamoto K, Taniguchi Y, Takeda S, Lavin MF, and Heierhorst J
- Journal Title
  
  PLoS Genetics
  
  Volume: 6 Issue: 10 Pages: e1001170-e1001170
- DOI
  10.1371/journal.pgen.1001170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710052
[Patent] 腫瘍治療用医薬組成物2024
- Inventor(s)
  平尾敦、Jing Yongwei、小林昌彦、中田光俊
- Industrial Property Rights Holder
  平尾敦、Jing Yongwei、小林昌彦、中田光俊
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23K06629
[Patent] 腫瘍治療用医薬組成物2021
- Inventor(s)
  平尾敦、Jing Yongwei、小林昌彦、中田光俊
- Industrial Property Rights Holder
  平尾敦、Jing Yongwei、小林昌彦、中田光俊
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K07566
[Presentation] Tumor microenvironment factor regulates malignant properties through transcription networks in glioblastoma2023
- Author(s)
  小林昌彦、Yongwei Jing、平尾敦
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K06629
[Presentation] Therapeutic advantage of targeting lysosome as signaling hub for metabolic conditions in malignant gliomas2023
- Author(s)
  Yongwei Jing, Masahiko Kobayashi, Atsushi Hirao
- Organizer
  AACR ANNUAL MEETING 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06629
[Presentation] A novel therapeutic strategy for glioma by targeting lysosome membrane integrity combined with amino acid restriction2022
- Author(s)
  Jing Yongwei、Kobayashi Masahiko、Hirao Atsushi
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07566
[Presentation] Identification of regulatory molecules of mesenchymal phenotype in glioblastoma2022
- Author(s)
  Kobayashi Masahiko、Jing Yongwei、Hirao Atsushi
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07566
[Presentation] A novel therapeutic strategy for glioblastoma by targeting lysosome membrane integrity controlled by autophagy activity2021
- Author(s)
  Yongwei Jing, Masahiko Kobayashi, Atsushi Hirao
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07566
[Presentation] Acquisition of therapy-resistance through proneural-mesenchymal transition in glioblastoma2021
- Author(s)
  Masahiko Kobayashi, Yongwei Jing, Atsushi Hirao
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07566
[Presentation] Investigation of the roles of OLIG2 in stemness property of glioblastoma2020
- Author(s)
  Masahiko Kobayashi, Atsushi Hirao
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07566
[Presentation] Construction of a reporter system of undifferentiated cells to characterize patient-derived glioma-initiating cells2019
- Author(s)
  小林昌彦、平尾敦
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07160
[Presentation] Identification of molecular targets in autophagy pathway to achieve efficient therapy of malignant gliomas2019
- Author(s)
  Kobayashi M, Vu HT, Hegazy AM, Jing Y, Chen X, Tadokoro Y, Ueno M, Kasahara A, Hirao A
- Organizer
  The 14th international symposium of the institute network for biomedical sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07160
[Presentation] Metabolic regulation of malignant phenotypes of glioma stem cells2018
- Author(s)
  Kobayashi M, Vu HT, Yamada D, Hegazy AM, Hirao A
- Organizer
  The 1st NanoLSI International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07160
[Presentation] Autophagy inhibition synergizes with calcium mobilization to achieve efficient therapy of malignant gliomas2018
- Author(s)
  小林昌彦、平尾敦
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K07160
[Presentation] mTOR複合体１のエネルギー代謝調節機構を介したグリオーマ幹細胞の悪性化の解析2015
- Author(s)
  小林昌彦、山田大祐、Hegazy Ahmed M.、平尾敦
- Organizer
  がん研究分野の特性等を踏まえた支援活動　公開シンポジウム
- Place of Presentation
  東京都千代田区一ツ橋　一橋講堂　学術総合センター２F
- Year and Date
  2015-01-28
- Data Source
  KAKENHI-PROJECT-25340028
[Presentation] mTOR複合体1活性化グリオーマの悪性化形質に対するミトコンドリア活性阻害の効果2015
- Author(s)
  Mohamed Hegazy Ahmed、小林昌彦、山田大祐、平尾敦
- Organizer
  第３回がんと代謝研究会
- Place of Presentation
  石川県立音楽堂（石川県金沢市）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-25340028
[Presentation] mTORC１の活性化によるグリオーマ幹細胞の悪性化の解析2015
- Author(s)
  小林昌彦、山田大祐、Hegazy Ahmed M.、平尾敦
- Organizer
  日本癌学会シンポジウム／共同利用・共同研究拠点シンポジウム
- Place of Presentation
  石川県金沢市　石川県立音楽堂交流ホール
- Year and Date
  2015-01-22
- Data Source
  KAKENHI-PROJECT-25340028
[Presentation] Efficient targeting malignant phenotypes of glioma by inhibition of mitochondrial activity2015
- Author(s)
  小林　昌彦、山田大祐、Mohamed Hegazy Ahmed、平尾敦
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25340028
[Presentation] グリオーマイニシエーティング細胞のエネルギー代謝制御におけるmTOR複合体1の役割2014
- Author(s)
  小林昌彦、山田大祐、Hegazy Ahmed M.、平尾敦
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  東京都葛飾区新宿　パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-25340028
[Presentation] mTOR複合体１による代謝調節を介したグリオーマ悪性化機構2014
- Author(s)
  小林昌彦、山田大祐、Hegazy Ahmed M.、平尾敦
- Organizer
  第２回がんと代謝研究会
- Place of Presentation
  東京都葛飾区新宿　東京理科大学葛飾キャンパス講堂
- Year and Date
  2014-07-11
- Data Source
  KAKENHI-PROJECT-25340028
[Presentation] DNA複製チェックポイントにおけるNBS1の役割2011
- Author(s)
  小林昌彦,林直之,山本健一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22710052
[Presentation] Arole for NBS1 in ATR activation2011
- Author(s)
  Kobayashi M, Hayashi N, Yamamoto K
- Organizer
  日本分子生物学会・第11回春季シンポジウム・金沢国際がん生物学シンポジウム
- Place of Presentation
  KKRホテル金沢(石川県)
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-22710052
[Presentation] A role for NBS1 in DNA replication checkpoint2011
- Author(s)
  小林昌彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22710052
[Presentation] A role for NBS1 in ATR activation2011
- Author(s)
  小林昌彦
- Organizer
  日本分子生物学会第11回春季シンポジウム
- Place of Presentation
  KKRホテル金沢(石川県)
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-22710052
[Presentation] A role for NBS1 in ATR activation2010
- Author(s)
  小林昌彦
- Organizer
  The Joint Symposium of the 5th International Symposium of Institute Network
- Place of Presentation
  KKRホテル金沢(石川県)
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-22710052
[Presentation] Arole for NBS1 in ATR activation, Molecular and Cellular Targets for Cancer, Infectious Diseases and Regeneration2010
- Author(s)
  Kobayashi M, Hayashi N, Yamamoto K
- Organizer
  The Joint Symposium of the 5th International Symposium of Institute Network and The International Symposium Commemorating Inauguration of Kanazawa University Cancer Research Institute
- Place of Presentation
  KKRホテル金沢(石川県)
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-22710052
[Presentation] SH基反応性代謝産物によるATMの活性化2010
- Author(s)
  小林昌彦
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22710052
[Presentation] SH基反応性代謝産物によるATMの活性化2010
- Author(s)
  小林昌彦,林直之,山本健一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル(大阪府)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22710052
[]
[]

1. 平尾敦

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 笠原敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 田所優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. 堂本貴寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 関政幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kobayashi masahiko 小林 昌彦

Kobayashi Masahiko 小林 昌彦

KOBAYASHI Masahiko 小林 昌彦

小林 昌彦 コバヤシ マサヒコ

Research Projects

Research Products

Co-Researchers

組織環境を介した可塑性によって規定される治療抵抗性の分子基盤Principal Investigator

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Molecular mechanism of subtype shift underlying plasticity and therapy-resistance in glioblastomaPrincipal Investigator

Principal Investigator

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Review Section

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Molecular mechanisms regulating energy metabolism and stemness propertyPrincipal Investigator

Principal Investigator

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Involvement of DNA damage-independent and ATM-dependent stress response in tumor suppressive mechanismPrincipal Investigator

Principal Investigator

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Activation mechanism and physiological role of the ATM checkpoint kinase in response to oxidative stressPrincipal Investigator

Principal Investigator

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酸化ストレスに抵抗する細菌ゲノム安定化機構の解析Principal Investigator

Principal Investigator

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Research Field

Research Institution

[Journal Article] Therapeutic potential of pentamidine for glioma‐initiating cells and glioma cells through multimodal antitumor effects2023

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DOI

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[Journal Article] Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation2023

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DOI

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[Journal Article] Therapeutic advantage of targeting lysosomal membrane integrity supported by lysophagy in malignant glioma2022

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[Journal Article] RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia2022

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[Journal Article] Essential role of autophagy in protecting neonatal haematopoietic stem cells from oxidative stress in a p62-independent manner2021

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DOI

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[Journal Article] Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples2020

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NAID

Data Source

[Journal Article] Identification of 2-Fluoropalmitic Acid as a Potential Therapeutic Agent Against Glioblastoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of GSK3β inhibitor kenpaullone as a temozolomide enhancer against glioblastoma2019

Author(s)

kobayashi masahiko 小林昌彦

Kobayashi Masahiko 小林昌彦

KOBAYASHI Masahiko 小林昌彦

小林昌彦コバヤシマサヒコ