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MADOIWA Seiji  窓岩 清治

… Alternative Names

窓岩 誠治  マドイワ セイジ

窓岩 精治  マドイワ セイジ

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Researcher Number 70296119
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-0806-5947
External Links
Affiliation (based on the past Project Information) *help 1999 – 2016: 自治医科大学, 医学部, 講師
2013: 自治医科大学, 分子病態治療研究センター分子病態研究部, 講師
1998: Division of Hemostasis and Thrombosis Research,, 医学部, 助手
Review Section/Research Field
Principal Investigator
Hematology / Hematology
Except Principal Investigator
Hematology / Hematology / General surgery / Otorhinolaryngology
Keywords
Principal Investigator
免疫寛容 / 血友病A / インヒビター / 第VIII因子欠損マウス / 遺伝子治療 / 血友病 / 細胞療法 / NOD / db / Hemophilia A … More / Factor VIII / マイクロポートシステム / ノックアウトマウス / マイクロポート / 植え込み型マイクロポートシステム / PAI-1欠損マウス / 人工多能性幹細胞 / 細胞移植療法 / 胸腺上皮細胞 / 血液凝固第VIII因子 / SIVウイルスベクター / 造血幹細胞 / 脂肪細胞 / SCIDマウス / dbマウス / 肝細胞 / Gene therapy / SIV virus vector / Hematopoietic stem cell / Adipocyte / SCID mice / db mice / 新生児 / ウイルスベクター / Immune tolerance / Neonate / knockout mice / 胸腺組織 / 制御性T細胞 / 胸腺 / SIVベクター / 抗第VIII因子インヒビター / 樹状細胞 / hemophilia A / factor VIII / inhibitor / immune tolerance / thymus / regulatory T cells / high resolution image system … More
Except Principal Investigator
血友病 / 遺伝子治療 / フィブリノゲン / 第VIII因子 / 第IX因子 / カニクイザル / 遺伝性異常フィブリノゲン / 電顕学的分析 / フィブリン / hereditary dysfibrinogen / fibrin / プラスミン / fibrinogen / 細胞移植 / 血栓症 / 血管内皮細胞 / プラスミノゲン / 出血傾向 / フィブリン超微細構造 / 余剰糖鎖 / 血栓性素因 / フィブリンの超微細構造 / bleeding tendency / fibrin ultra-structure / 血友病A / Hemophilia / Gene therapy / Factor VIII / Factor IX / adeno-associated virus vector / SIV vector / 第IX / 耳科学 / 感音難聴 / 線溶系遺伝子 / アデノ随伴ウイルスベクター / 血友病Aクローンブタ / hemophilia / gene therapy / 遺伝子細胞治療 / 人工多能性幹細胞 / iPS細胞 / 造血幹細胞 / Niche / 細胞周期 / 転写因子 / 造血幹細胞ニッチ / 血栓塞栓症 / 接着分子 / 線維芽細胞 / β1インテグリン / キニノゲン / 出血性素因 / インテグリン / 腫瘍の転移 / 分子異常 / フィブリンの電顕像 / フィブリン重合 / 一過性虚血発作 / 接着分子受容体 / RGD配列 / thromboembolism / electron microscopy / adhesion molecule / beta1-integrin / kininogen / α2-プラスミンインヒビタ / アンギオスタチン / XIII因子 / 細胞遊走 / セレクチン / α2プラスミンインヒビタ / 架橋結合 / 細胞移動 / 組織修復 / plasminogen / alpha2-plasmin inhibitor / angiostatin / factor XIII / selectin / 構造異常 / モノクロナル抗体 / 抗血管新生 / 点変異 / 抗フィブリノゲン・モノクロナル抗体 / structural alteration / thrombosis / monoclonal antibody / anti-angiogenesis / 遺伝性フィブリノゲン / フィブリノゲンの構造 / フィブリン網 / 遺伝子解析 / 余剩糖鎖 / フィブリノゲン異常症 / 糖付加構造 / 停止コドンの消失 / fibrinogen structure / extra carbohydrate / fibrin nets / gene analysis / アデノ随伴ウイルス / AAVベクター / 凝固第VIII因子 / プロモーター / 血清型 / 骨格筋 / 肝臓 / エリスロポエチン / adeno-associated virus / AAV vector / Hemophilia A / Coagnlation Factor VIII / promoters / serotype / skeletal muscle / liver / プラスミノゲンアクチベータインヒビタ1 / 白血球由来エラスターゼ / プラスミノゲンノックアウトマウス / フィブリン分解産物 / 白血球エラスターゼ / フィブリノゲン分解産物 / Plasminogen activator inhibitor-1 / granulocyte-derived elastase / Plasmin / plasminogen-deficient mice / 血管修復 / 血栓 / コラーゲン / 細胞支持体 / 損傷細胞 / 創傷治癒 / 血管壁 / 人工血管 / fibrin networks / blood vessels / injury / HUVEC / collagen / wound healing / repairement / SIVベクター / Adeno-associated virus / Adeno-associated virus vector / ウイルスベクター / 凝固VIII因子 / 凝固IX因子 / 血小板 / 遣伝子治療 / 凝固VIII因 Less
  • Research Projects

    (20 results)
  • Research Products

    (233 results)
  • Co-Researchers

    (16 People)
  •  The role of Foxf1a for the function of hematopoietic stem cells

    • Principal Investigator
      Ohmori Tsukasa
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Development of novel thymus-directed strategy for central immune tolerance induction in hemophilia APrincipal Investigator

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  次世代血友病治療法の開発と非ヒト霊長類を用いた前臨床研究

    • Principal Investigator
      三室 淳
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Application of iPSCs for hemophilia therapy

    • Principal Investigator
      OHMORI Tsukasa
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Regulation of plasminogen activator inhibitor-1 promotes the immune response to factor VIII in murine hemophilia A.Principal Investigator

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Hearing functional analysis of fibrinolytic components gene mutant mice

    • Principal Investigator
      ISHIKAWA Kotaro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Jichi Medical University
  •  Preclinical Hemophilia Gene Therapy Study with Non-human Primates

    • Principal Investigator
      MIMURO Jun
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Development of immune-tolerance induction by continuous infusion of FactorVIII using micro-injection system in murine hemophilia APrincipal Investigator

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Preclinical Study for Hemophilia Gene and Cell Therapy in Model Mice and in Non-human Primates

    • Principal Investigator
      MIMURO Jun
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Induction of factor VIII specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia APrincipal Investigator

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  Gene therapy for hemophilia and its preclinical study in cynomolgus macaques

    • Principal Investigator
      MIMURO Jun
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  Induction of Immune Tolerance by Neonatal Intravenous Injection of Human Factor VIII in Murine Hemophilia APrincipal Investigator

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      JICFII MEDICAL SCHOOL
  •  Involvement of the fibrin networks on the repairement of the injured blood vessels

    • Principal Investigator
      SUGO Teruko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Regulation of granulocyte-derived elastase-dependent fibrinolysis

    • Principal Investigator
      SAKATA Yoichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Gene therapy for hemophilia A with simian immunodeficiency virus agmTYO1-based vectors carrying human factor VIII gene.Principal Investigator

    • Principal Investigator
      MADOIWA Seiji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  Fundamental researches toward gene therapy of Hemophilia A utilizing adeno-associated virus vectors

    • Principal Investigator
      MIZUKAMI Hiroaki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School
  •  STUDIES ON THE PATHOPHYSIOLOGY OF THROMBOEMBOLIC DISEASES WITH SPECIAL REFERENCE TO THE UNDERLYING IMPAIRED BLOOD COAGULATION AND ITS REGULATION

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  Molecular basis for the fibrinogen structure and functions-Analysis Of hereditary dysfibrinogens and their application to the study

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School
  •  Analysis of the molecular mechanism in regulation of cell migration by alpha2-plasmin inhibitor

    • Principal Investigator
      SAKATA Yoichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical School, School of Medicine
  •  Etiology and pathophysiology of thrombosis : A molecular biological aproach to elucidate disturbed mechanisms of blood coagulation and its inhibition.

    • Principal Investigator
      MATSUDA Michio
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      Jichi Medical School, School of Medicine

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] 血液専門医テキスト2011

    • Author(s)
      窓岩清治, 他
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Book] 血液内科ゴールデンハンドブック2011

    • Author(s)
      窓岩清治, 他
    • Total Pages
      462
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Book] 血液内科ゴールデンハンドブック2011年2011

    • Author(s)
      窓岩清治, 他
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Book] 周産期の出血と血栓症2004

    • Author(s)
      窓岩 清治
    • Total Pages
      476
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-15591021
  • [Journal Article] Endothelial cells and fibrinolysis in sepsis-induced DIC2015

    • Author(s)
      Madoiwa, S.
    • Journal Title

      J Intensive Care

      Volume: 3 Pages: 1-8

    • DOI

      10.1186/s40560-015-0075-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Combination of thrombin-antithrombin complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational study.2014

    • Author(s)
      Koyama, K., S. Madoiwa, S. Nunomiya, T. Koinuma, M. Wada, A. Sakata, T. Ohmori, J. Mimuro, and Y. Sakata.
    • Journal Title

      Crit Care

      Volume: 18

    • DOI

      10.1186/cc13190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Paxillin is an intrinsic negative regulator of platelet activation in mice.2014

    • Author(s)
      Sakata, A., T. Ohmori, S. Nishimura, H. Suzuki, S. Madoiwa, J. Mimuro, K. Kario, and Y. Sakata.
    • Journal Title

      Thromb J

      Volume: 12 Pages: 1-1

    • DOI

      10.1186/1477-9560-12-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Production of functional coagulation factor VIII from iPSCs using a lentiviral vector2014

    • Author(s)
      Kashiwakura Y, Ohmori T, Mimuro J, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y
    • Journal Title

      Haemophilia

      Volume: 20

    • Data Source
      KAKENHI-PROJECT-23591427
  • [Journal Article] Changes in blood coagulation-fibrinolysis markers by pneumatic tourniquet during total knee joint arthroplasty with venous thromboembolism.2014

    • Author(s)
      Watanabe, H., I. Kikkawa, S. Madoiwa, H. Sekiya, S. Hayasaka, and Y. Sakata.
    • Journal Title

      J Arthroplasty

      Volume: 29 Pages: 569-573

    • DOI

      10.1016/j.arth.2013.08.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Production of functional coagulation factor VIII from iPSCs using a lentiviral vector.2014

    • Author(s)
      Kashiwakura Y, Ohmori T, Mimuro J, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y.
    • Journal Title

      Haemophilia.

      Volume: 20

    • DOI

      10.1111/hae.12311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
  • [Journal Article] Addition of recommendations for the use of recombinant human thrombomodulin to the "Expert consensus for the treatment of disseminated intravascular coagulation in Japan"2014

    • Author(s)
      Wada, H., D. I. C. s. Japanese Society of Thrombosis Hemostasis, K. Okamoto, T. Iba, S. Kushimoto, K. Kawasugi, S. Gando, S. Madoiwa, T. Uchiyama, T. Mayumi, and Y. Seki.
    • Journal Title

      Thromb Res

      Volume: 2014 Pages: 924-925

    • DOI

      10.1016/j.thromres.2014.07.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] The prevalence of neutralizing antibodies against adeno-associated virus capsids is reduced in young japanese individuals2014

    • Author(s)
      Mimuro J, Mizukami H, Shima M, Matsushita T, Taki M, Muto S, Higasa S, Sakai M, Ohmori T, Madoiwa S, Ozawa K, and Sakata Y.
    • Journal Title

      Journal of Medical Virology

      Volume: 86 Pages: 1990-1997

    • DOI

      10.1002/jmv.23818

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430, KAKENHI-PROJECT-25461460
  • [Journal Article] Living donor liver transplantation from an asymptomatic donor with mild coagulation factor IX deficiency: report of a case.2014

    • Author(s)
      Sanada, Y., H. Sasanuma, Y. Sakuma, K. Morishima, N. Kasahara, Y. Kaneda, A. Miki, T. Fujiwara, A. Shimizu, M. Hyodo, Y. Hirata, N. Yamada, N. Okada, Y. Ihara, T. Urahashi, S. Madoiwa, J. Mimuro, K. Mizuta, and Y. Yasuda.
    • Journal Title

      Pediatr Transplant

      Volume: 18

    • DOI

      10.1111/petr.12358

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Acquired hemophilia A caused by factor VIII inhibitors: report of a case2013

    • Author(s)
      Hosoya Y, Matsumura M, Madoiwa S, Zuiki T, Matsumoto S, Nunomiya S, Lefor A, Sata N, Yasuda Y.
    • Journal Title

      Surg Today

      Volume: 43 Pages: 670-674

    • DOI

      10.1007/s00595-012-0290-x

    • NAID

      10031176090

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] インヒビター保有先天性血友病患者に対する止血治療ガイドライン 2013年改訂版2013

    • Author(s)
      酒井 道生(産業医科大学 小児科), 瀧 正志, 家子 正裕, 井田 孔明, 大平 勝美, 勝沼 俊雄, 高橋 芳右, 野上 恵嗣, 日笠 聡, 福武 勝幸, 松下 功, 松本 雅則, 窓岩 清治, 天野 景裕, 岡 敏明, 荻原 建一, 澤田 暁宏, 嶋 緑倫, 白幡 聡, 鈴木 隆史, 竹谷 英之, 花房 秀次, 堀越 泰雄, 松下 正, 松本 剛史, 三室 淳, 吉岡 章
    • Journal Title

      日本血栓止血学会誌

      Volume: 24 Pages: 640-658

    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Minimizing the Inhibitory Effect of Neutralizing Antibody for Efficient Gene Expression in the Liver With Adeno-associated Virus 8 Vectors2013

    • Author(s)
      Mimuro J, Mizukami H, Hishikawa S, Ikemoto T, Ishiwata A, Sakata A, Ohmori T, Madoiwa S, Ono F, Ozawa K, Sakata Y
    • Journal Title

      Mol Ther

      Volume: 21 Pages: 318-323

    • Data Source
      KAKENHI-PROJECT-23591427
  • [Journal Article] Minimizing the inhibitory effect of neutralizing antibody for efficient geneexpression in the liver with adeno-associated virus 8 vectors.2013

    • Author(s)
      Mimuro J, Mizukami H, Hishikawa S, Ikemoto T, Ishiwata A, Sakata A, Ohmori T, Madoiwa S, Ono F, Ozawa K, and Sakata Y
    • Journal Title

      Mol. Ther.

      Volume: 21 Pages: 318-323

    • DOI

      10.1038/mt.2012.258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
  • [Journal Article] 血友病aクローンブタ2013

    • Author(s)
      柏倉裕志, 三室淳, 大西彰, 岩元正樹, 窓岩清治, 淵本大一郎, 鈴木俊一, 鈴木美佐枝, 千本昭一郎, 石渡彰, 安本篤史, 坂田飛鳥, 大森司, 橋本径子, 矢崎智子, 坂田洋一
    • Journal Title

      日本血栓止血学会誌

      Volume: 24 Pages: 224-224

    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Overexpression of factor vii ameliorates bleeding diathesis of factor viii-deficient mice with inhibitors.2013

    • Author(s)
      Yasumoto A, Madoiwa S, Kashiwakura Y, Ishiwata A, Ohmori T, Mizukami H. Ozawa K, Sakata Y, and Mimuro J.
    • Journal Title

      Thromb Res.

      Volume: 131 Pages: 444-449

    • DOI

      10.1016/j.thromres.2013.03.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
  • [Journal Article] Acquired factor v inhibitor associated with life-threatening bleeding and a mixing test result that indicated coagulation factor deficiency.2013

    • Author(s)
      Ashizawa M, Kimura S, Wada H, Sakamoto K, Sato M, Terasako K, Kikuchi M, Nakasone H, Okuda S, Kako S, Yamazaki R, Oshima K, Matsuura K, Ohmori T, Madoiwa S, Nishida J, Mimuro J, Tabei K, Sakata Y, Kanda Y.
    • Journal Title

      Hematology

      Volume: 18 Pages: 300-304

    • DOI

      10.1179/1607845412y.0000000072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Tissue plasminogen activator deficiency promotes early phase regeneration in the olfactory epithelium after bulbegtomy.2013

    • Author(s)
      Makino N, Madoiwa S, Ohmori T, Katoh K, Ookawara S, Kanazawa T, Matsuo O, Ichikawa M, Mimuro J, Ichimura K, Sakata Y
    • Journal Title

      Int Forum Allergy Rhinol

      Volume: 3 Pages: 458-467

    • DOI

      10.1002/alr.21124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570084, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-24591430
  • [Journal Article] Evaluation of hemostatic biomarker abnormalities that precede platelet count decline in critically ill patients with sepsis2013

    • Author(s)
      Koyama, K., Madoiwa, S., Tanaka, S., Koinuma, T., Wada, M., Sakata, A., Ohmori, T., Mimuro, J., Nunomiya, S. and Sakata, Y.
    • Journal Title

      J Crit Care

      Volume: in press

    • DOI

      10.1016/j.jcrc.2012.10.069

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Overexpression of factor VII ameliorates bleeding diathesis of factor VIII-deficient mice with inhibitors2013

    • Author(s)
      Yasumoto A, Madoiwa S, Kashiwakura Y, Ishiwata A, Ohmori T, Mizukami H, Ozawa K, Sakata Y, Mimuro J
    • Journal Title

      Thromb Res

      Volume: 131 Pages: 444-449

    • Data Source
      KAKENHI-PROJECT-23591427
  • [Journal Article] 分娩後後天性血友病の2例.2013

    • Author(s)
      野城聡志, 翁家国, 岡塚貴世志, 藤原慎一郎, 大嶺謙, 鈴木隆浩, 森政樹, 永井正, 室井一男, 小澤敬也, 窓岩清治.
    • Journal Title

      臨床血液

      Volume: 54 Pages: 2100-2100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Journal Article] Immune response against serial infusion offactor VIII antigen through an implantable venous-access device system in haemophilia A mice.Haemophilia.2012

    • Author(s)
      Madoiwa, S., et al.
    • Journal Title

      Haemophilia.

      Volume: 18

    • DOI

      10.1111/j.1365-2516.2011.02686.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591249, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
  • [Journal Article] Il2rg Gene-Targeted Severe Combined Immunodeficiency(SCID) Pigs2012

    • Author(s)
      Suzuki, S., Iwamoto, M., Saito, Y., Fuchimoto, D., Sembon, S., Suzuki, M., Mikawa, S., Hashimoto, M., Aoki, Y., Najima, Y., Takagi, S., Suzuki, N., Suzuki, E., Kubo, M., Mimuro, J., Kashiwakura, Y., Madoiwa, S., Sakata, Y., Perry, A. C. F., Ishikawa, F.
    • Journal Title

      Cell Stem Cell

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Morphological assessment of the luminal surface of olfactory epithelium in mice deficient in tissue plasminogen activator following bulbectomy2012

    • Author(s)
      Makino, N
    • Journal Title

      J Laryngol Otol

      Volume: 126(11) Pages: 1114-1120

    • DOI

      10.1017/s002221511200206x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-24591430
  • [Journal Article] Intra-articular injection of mesenchymal stem cells expressing coagulation factor ameliorates hemophilic arthropathy in factor VIII-deficient mice2012

    • Author(s)
      Kashiwakura, Y
    • Journal Title

      J Thromb Haemost

      Volume: 10(9) Pages: 1802-1813

    • DOI

      10.1111/j.1538-7836.2012.04851.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-23659493, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24591430
  • [Journal Article] Lack of association between serum paraoxonase-1 activity and residual platelet aggregation during dual anti-platelet therapy2012

    • Author(s)
      Ohmori, T., Yano, Y., Sakata, A., Ikemoto, T., Shimpo, M., Madoiwa, S., Katsuki, T., Mimuro, J., Shimada, K., Kario, K., et al
    • Journal Title

      Thromb Res

      Volume: 129

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Il2rg gene-targeted severe combined immunodeficiency pigs2012

    • Author(s)
      Suzuki S, Iwamoto M, Saito Y, Fuchimoto D, Sembon S, Suzuki M, Mikawa S, Hashimoto M, Aoki Y, Najima Y, Takagi S, Suzuki N, Suzuki E, Kubo M, Mimuro J, Kashiwakura Y, Madoiwa S, et al.
    • Journal Title

      Cell Stem Cell

      Volume: 10 Pages: 753-758

    • DOI

      10.1016/j.stem.2012.04.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591430, KAKENHI-ORGANIZER-24111001
  • [Journal Article] FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms2012

    • Author(s)
      Norimatsu, Y., Ohmori, T., Kimura, A., Madoiwa, S., Mimuro, J., Seichi, A., Yatomi, Y., Hoshino, Y., and Sakata, Y
    • Journal Title

      Am J Pathol

      Volume: 180 Pages: 1625-1635

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Porcine model of hemophilia A2012

    • Author(s)
      Kashiwakura Y
    • Journal Title

      PloS one

      Volume: 7(11)

    • DOI

      10.1371/journal.pone.0049450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
  • [Journal Article] FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms.2012

    • Author(s)
      Norimatsu Y, Ohmori T, Kimura A, Madoiwa S, Mimuro J, Seichi A, Yatomi Y, Hoshino Y, Sakata Y.
    • Journal Title

      Am J Pathol.

      Volume: 180(4) Pages: 1625-1635

    • DOI

      10.1016/j.ajpath.2011.12.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591641, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
  • [Journal Article] Porcine model of hemophilia A2012

    • Author(s)
      Kashiwakura Y, Mimuro J, Onishi A, Iwamoto M, Madoiwa S, Fuchimoto D, Suzuki S, Suzuki M, Sembon S, Ishiwata A, Yasumoto A, Sakata A, Ohmori T, Hashimoto M, Yazaki S, Sakata Y
    • Journal Title

      PLoS One

      Volume: 7

    • Data Source
      KAKENHI-PROJECT-23591427
  • [Journal Article] Lack of association between serum paraoxonase-1 activity and residual platelet aggregation during dual anti-platelet therapy.2012

    • Author(s)
      Ohmori, T., et al.
    • Journal Title

      Thromb Res.

      Volume: 129

    • DOI

      10.1016/j.thromres.2011.10.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591249, KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427, KAKENHI-PROJECT-24591430
  • [Journal Article] Immune response against serial infusion of factor VIII antigen through an implantable venous-access device system in haemophilia A mice2012

    • Author(s)
      Madoiwa S, Kobayashi E, Kashiwakura Y, Sakata A, Yasumoto A, Ohmori T, Mimuro J, Sakata Y
    • Journal Title

      Haemophilia

      Volume: 18

    • Data Source
      KAKENHI-PROJECT-23591427
  • [Journal Article] Intra-articular injection of mesenchymal stem cells expressing coagulation factor ameliorates hemophilic arthropathy in factor VIII-deficient mice2012

    • Author(s)
      Kashiwakura Y, Ohmori T, Mimuro J, Yasumoto A, Ishiwata A, Sakata A, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y
    • Journal Title

      J Thromb Haemost

      Volume: 10 Pages: 1802-1813

    • Data Source
      KAKENHI-PROJECT-23591427
  • [Journal Article] Immune response against serial infusion of factor VIII antigen through an implantable venous-access device system in haemophilia A mice2012

    • Author(s)
      Madoiwa, S., Kobayashi, E., Kashiwakura, Y., Sakata, A., Yasumoto, A., Ohmori, T., Mimuro, J., and Sakata, Y
    • Journal Title

      Haemophilia

      Volume: 18

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Degradation of cross-linked fibrin by leukocyte elastase as alternative pathway for plasmin-mediated fibrinolysis in sepsis-induced disseminated intravascular coagulation2011

    • Author(s)
      Madoiwa, S., Tanaka, H., Nagahama, Y., Dokai, M., Kashiwakura, Y., Ishiwata, A., Sakata, A., Yasumoto, A., Ohmori, T., Mimuro, J., et al
    • Journal Title

      Thromb Res

      Volume: 127 Pages: 349-355

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Predictive blood coagulation markers for early diagnosis of venous thromboembolism after total knee joint replacement2011

    • Author(s)
      Watanabe, H. Madoiwa, S. Sekiya, H. Nagahama, Y. Matsuura, S. Kariya, Y. Ohmori, T. Mimuro, J. Hoshino, Y. Hayasaka, S. Sakata, Y.
    • Journal Title

      Thromb Res.

      Volume: 128

    • DOI

      10.1016/j.thromres.2011.07.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427
  • [Journal Article] Local regulation of neutrophil elastase activity by endogenous alpha1-antitrypsin in lipopolysaccharide-primed hematological cells2011

    • Author(s)
      Dokai, M., Madoiwa, S., Yasumoto, A., Kashiwakura, Y., Ishiwata, A., Sakata, A., Makino, N., Ohmori, T., Mimuro, J., and Sakata, Y
    • Journal Title

      Thromb Res

      Volume: 128 Pages: 283-292

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Degradation of cross-linked fibrin by leukocyte elastase as alternative pathway for plasmin-mediated fibrinolysis in sepsis-induced disseminated intravascular coagulation.2011

    • Author(s)
      Madoiwa, S.
    • Journal Title

      Thromb Res.

      Volume: 127 Pages: 349-355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Predictive blood coagulation markers for early diagnosis of venous thromboembolism after total knee joint replacement2011

    • Author(s)
      Watanabe, H., Madoiwa, S., Sekiya, H., Nagahama, Y., Matsuura, S., Kariya, Y., Ohmori, T., Mimuro, J., Hoshino, Y., Hayasaka, S., et al
    • Journal Title

      Thromb Res

      Volume: 128

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Cross-linked fibrin degradation products by leukocyte elastase (e-XDP)2011

    • Author(s)
      Madoiwa, S., et al.
    • Journal Title

      Rinsho Byori

      Volume: 147 Suppl Pages: 65-70

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Degradation of cross-linked fibrin by leukocyte elastase as alternative pathway for plasmin-mediated fibrinolysis in sepsis-induced disseminated intravascular coagulation.2011

    • Author(s)
      Madoiwa, S. Tanaka, H. Nagahama, Y. Dokai, M. Kashiwakura, Y. Ishiwata, A. Sakata, A. Yasumoto, A. Ohmori, T. Mimuro, J. Sakata, Y.
    • Journal Title

      Thromb Res.

      Volume: 127 Pages: 349-355

    • DOI

      10.1016/j.thromres.2010.12.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427
  • [Journal Article] Local regulation of neutrophil elastase activity by endogenouse alpha-1 antitrypsin in lipopolysaccharide-primed hematological cells2011

    • Author(s)
      Dokai, M., Madoiwa, S., Yasumoto, A., Kashiwakura, Y., Ishiwata, A., Sakata, A., Makino, N., Ohmori, T., Mimuro, J., and Sakata, Y.
    • Journal Title

      Thromb Res.

      Volume: 128 Pages: 283-292

    • DOI

      10.1016/j.thromres.2011.04.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591426, KAKENHI-PROJECT-23591427
  • [Journal Article] Degradation of cross-linked fibrin by leukocyte elastase as alternative pathway for plasmin-mediated fibrinolysis in sepsis-induced disseminated intravascular coagulation.2011

    • Author(s)
      Madoiwa, S.
    • Journal Title

      Thromb Res

      Volume: 127 Pages: 349-355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Frequency and hemostatic abnormalities in pre-DIC patients2010

    • Author(s)
      Okamoto, K., Wada, H., Hatada, T., Uchiyama, T., Kawasugi, K., Mayumi, T., Gando, S., Kushimoto, S., Seki, Y., Madoiwa, S., et al
    • Journal Title

      Thromb Res

      Volume: 126 Pages: 74-78

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Vinculin activates inside-out signaling of integrin alphaIIbbeta3 in Chinese hamster ovary cells2010

    • Author(s)
      Ohmori, T., Kashiwakura, Y., Ishiwata, A., Madoiwa, S., Mimuro, J., Honda, S., Miyata, T., and Sakata, Y
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 400 Pages: 323-328

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Modified non-overt DIC diagnostic criteria predict the early phase of overt-DIC2010

    • Author(s)
      Wada, H., Hatada, T., Okamoto, K., Uchiyama, T., Kawasugi, K., Mayumi, T., Gando, S., Kushimoto, S., Seki, Y., Madoiwa, S., et al
    • Journal Title

      Am J Hematol

      Volume: 85 Pages: 691-694

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Impact of acute cellular rejection on coagulation and fibrinolysis biomarkers within the immediate post-operative period in pediatric liver transplantation2010

    • Author(s)
      Mimuro, J., Mizuta, K., Kawano, Y., Hishikawa, S., Hamano, A., Kashiwakura, Y., Ishiwata, A., Ohmori, T., Madoiwa, S., Kawarasaki, H., et al
    • Journal Title

      Pediatr Transplant

      Volume: 14 Pages: 369-376

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Dynamics of blood coagulation and fibrinolysis and laboratory findings in disseminated intravascular coagulation.2010

    • Author(s)
      Madoiwa, S.
    • Journal Title

      Rinsho Ketsueki

      Volume: 51 Pages: 20-28

    • NAID

      10026331957

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Mutant macaque factor IX T262A:A tool for hemophilia B gene therapy studies in macaques.2010

    • Author(s)
      Ishiwata A., Mimuro J., Mizukami H., Kashiwakura Y., Yasumoto A., Sakata A., Ohmori T., Madoiwa S., Ono F., Shima M., Yoshioka A., Ozawa K., Sakata Y.
    • Journal Title

      Thromb Res 125(6)

      Pages: 533-537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Vinculin activates inside-out signaling of integrin alphaIIbβ3 in Chinese hamster ovary cells.2010

    • Author(s)
      Ohmori T., Kashiwakura Y., Ishiwata A,. Madoiwa S., Mimuro J., Honda S., Miyata T., Sakata Y.
    • Journal Title

      Biochem Biophys Res Commun 400(3)

      Pages: 323-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Expert consensus for the treatment of disseminated intravascular coagulation in Japan2010

    • Author(s)
      Wada, H., Asakura, H., Okamoto, K., Iba, T., Uchiyama, T., Kawasugi, K., Koga, S., Mayumi, T., Koike, K., Gando, S., Madoiwa, S., et al
    • Journal Title

      Thromb Res

      Volume: 125 Pages: 6-11

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Liver-restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII-deficient mice2010

    • Author(s)
      Ishiwata, A., Mimuro, J., Mizukami, H., Kashiwakura, Y., Takano, K., Ohmori, T., Madoiwa, S., Ozawa, K., and Sakata, Y.
    • Journal Title

      J Gene Med

      Volume: 11 Pages: 1020-1029

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Mutant macaque factor IX T262A : a tool for hemophilia B gene therapy studies in macaques2010

    • Author(s)
      Ishiwata, A., Mimuro, J., Mizukami, H., Kashiwakura, Y., Yasumoto, A., Sakata, A., Ohmori, T., Madoiwa, S., Ono, F., Shima, M., et al
    • Journal Title

      Thromb Res

      Volume: 125 Pages: 533-537

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] 特集:血友病のインヒビターを考察する「総説」インヒビターの発生と免疫寛容2010

    • Author(s)
      窓岩清治
    • Journal Title

      日本血栓止血学会誌

      Volume: 21 Pages: 496-505

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] 感染症DICを考慮した現厚生労働省DIC診断基準の検討2010

    • Author(s)
      窓岩清治
    • Journal Title

      日本血栓止血学会誌

      Volume: 21 Pages: 595-599

    • NAID

      10027675302

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Development of platelet-directed gene modification by lentiviral vector.2010

    • Author(s)
      Ohmori T., Madoiwa S., Mimuro J., Sakata Y.
    • Journal Title

      Rinsho Ketsueki 51(8)

      Pages: 625-631

    • NAID

      10026630183

    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Impacto of acute cellular rejection on coagulation and f ibrinolysis biomarkers within the immediate post-operative reriod in pediatric liver transplantation.2010

    • Author(s)
      Mimuro J., Mizuta K., Kawano Y., Hishikawa S., Hamano A., Kashiwakura Y., Ishiwata A., Ohmori T., Madoiwa S., Kawarasaki H., Sakata Y.
    • Journal Title

      Pediatr Transplant 14(3)

      Pages: 369-376

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Vinculin is indispensable for repopulation by hematopoietic stem cells, independent of integrin function.2010

    • Author(s)
      Ohmori, T., Kashiwakura,Y., Ishiwata, A., Madoiwa,S., Mimuro,J., Furukawa, Y., Sakata, Y.
    • Journal Title

      J Biol Chem 285(41)

      Pages: 31763-31773

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Vinculin is indispensable for repopulation by hematopoietic stem cells2010

    • Author(s)
      Ohmori, T., Kashiwakura, Y., Ishiwata, A., Madoiwa, S., Mimuro, J., Furukawa, Y., and Sakata, Y
    • Journal Title

      Vinculin is indispensable for repopulation by hematopoietic stem cells

      Volume: 285 Pages: 31763-31773

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A2009

    • Author(s)
      Madoiwa S
    • Journal Title

      J Thromb Haemost 7(5)

      Pages: 811-824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A2009

    • Author(s)
      Madoiwa, S.
    • Journal Title

      J Thromb Haemost. 7(5)

      Pages: 811-824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII infection in murine hemophilia A2009

    • Author(s)
      Madoiwa, S., et al.
    • Journal Title

      J Thromb Haemost 7

      Pages: 811-824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Prevalence of genetic mutations in protein S, protein C and antithrombin genes in Japanese patients with deep vein thrombosis.2009

    • Author(s)
      Miyata T, Sato Y, Ishikawa J, Okada H, Takeshita S, Sakata T, Kokame K, Kimura R, Honda S, Kawasaki T, Suehisa E, Tsuji H, Madoiwa S, Sakata Y, Kojima T, Murata M, Ikeda Y.
    • Journal Title

      Thromb Res. 124

      Pages: 14-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A.2009

    • Author(s)
      Madoiwa S., Yamauchi T., Kobayashi E., Hakamata Y., Dokai M., Makino N., Kashiwakura Y., Ishiwata A., Ohmori T., Mimuro J., Sakata Y.
    • Journal Title

      J Thromb Haemost 7(5)

      Pages: 811-824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A2009

    • Author(s)
      Madoiwa, S., Yamauchi, T., Kobayashi, E., Hakamata, Y., Dokai, M., Makino, N., Kashiwakura, Y., Ishiwata, A., Ohmori, T., Mimuro, J., et al
    • Journal Title

      J Thromb Haemost

      Volume: 7 Pages: 811-824

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Liver-restricted expression of the canine factor VIII-gene facilitates prevention of inhibitor formation in factor VIII-deficient mice.2009

    • Author(s)
      Ishiwata A., Mimuro J., Mizukami H., Kashiwakura Y., Takano K., Ohmori T., Madoiwa S., Ozawa K., Sakata Y.
    • Journal Title

      J Gene Med 11(11)

      Pages: 1020-1029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Prevalence of genetic mutations in protein S, protein C and antithrombin genes in Japanese patients with deep vein thrombosis2009

    • Author(s)
      Miyata, T., Sato, Y., Ishikawa, J., Okada, H., Takeshita, S., Sakata, T., Kokame, K., Kimura, R., Honda, S., Kawasaki, T., Madoiwa, S., et al
    • Journal Title

      Thromb Res

      Volume: 124 Pages: 14-18

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Association of Asn221Ser mutation in tissue factor pathway inhibitor-beta with plasma total tissue factor pathway inhibitor level2009

    • Author(s)
      Ishikawa, J., Okada, H., Kato, H., Takeshita, S., Honda, S., Kawasaki, T., Suehisa, E., Tsuji, H., Madoiwa, S., Sakata, Y., et al
    • Journal Title

      Blood Coagul Fibrinolysis

      Volume: 20 Pages: 22-26

    • Data Source
      KAKENHI-PROJECT-21591249
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A.2009

    • Author(s)
      Madoiwa S, Yamauchi T, Kobayashi E, Hakamata Y, Dokai M, Makino N, Kashiwakura Y, Ishiwata A, Ohmori T, Mimuro J, Sakata Y.
    • Journal Title

      J Thromb Haemost. 7

      Pages: 811-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Induction of factor VIII-specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A2009

    • Author(s)
      Madoiwa S
    • Journal Title

      J Thromb Haemost 7(5)

      Pages: 811-824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Dysfibrinogen Kagoshima with the amino acid substitution gammaThr-314 to Ile: analyses of molecular abnormalities and thrombophilic nature of this abnormal molecule.2008

    • Author(s)
      Niwa K, Mimuro J, Miyata M, Sugo T, Ohmori T, Madoiwa S, Tei C, Sakata Y.
    • Journal Title

      Thromb Res. 121

      Pages: 773-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Dysfibrinogen Kagoshima with the amino acid substitution gammaThr-314 to Ile: analyses of molecular abnormalities and thrombophilic nature of this abnormal molecule.2008

    • Author(s)
      Niwa K, Mimuro J, Miyata M, Sugo T, Ohmori T, Madoiwa S, Tei C, Sakata Y.
    • Journal Title

      Thromb Res. 124(1)

      Pages: 14-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Determinants of thrombbbbf thrombthrombof thrombthrombf thromb thrombrombrombhrombeneration, fibrinolytic activity, and endothelial dysfunction in dual-antiplatelet therapy : nvolvement of factors other than platelet aggregability in Virchow's triad.2008

    • Author(s)
      Yano Y., Ohmori T., Hoshide S., Madoiwa S., Yamamoto K., Katsuki T., Mitsuhashi T., Mimuro J., Shimada K., Kario K., Sakata Y.
    • Journal Title

      European Heart Journal Jul 29(14)

      Pages: 1729-1738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Phenotypic correction of hemophilia A by ectopic expression of activated factor VII in platelets.2008

    • Author(s)
      Ohmori T, Ishiwata A, Kashiwakura Y, Madoiwa S, Mitomo K, Suzuki H, Hasegawa M, Mimuro J, Sakata Y.
    • Journal Title

      Mol Ther. 16

      Pages: 1359-65

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain infarction.2008

    • Author(s)
      Kimura.,A., Ohmori,T., Kashiwakura.Y., Ohkawa,R., Madoiwa,S., Mimuro,J., Shimazaki,K., Hoshino,Y., Yatomi,Y., Sakata,Y.
    • Journal Title

      Stroke. Dec 39(12)

      Pages: 3411-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Unbalanced expression of ADAMTS13 and von Willebrand factor in mouse endotoxinemia.2008

    • Author(s)
      Mimuro J, Niimura M, Kashiwakura Y, Ishiwata A, Ono T, Ohmori T, Madoiwa S, Okada K, Matsuo O, Sakata Y.
    • Journal Title

      Thromb Res. 122

      Pages: 91-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Phenotypic orrection of hemophilia A by ectopic expression of activated factor FVII in platelets.2008

    • Author(s)
      Ohmori,T., Ishiwata,A., Kashiwakura,Y., Madoiwa, S., Mitomo,K., Suzuki,H., Hasegawa,M., Mimuro,J.,Sakata,Y.
    • Journal Title

      Mol Ther 16(8)

      Pages: 1359-1363

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Determinants of thrombin generation, fibrinolytic activity, and endothelial dysfunction in patients on dual antiplatelet therapy: involvement of factors other than platelet aggregability in Virchow's triad.2008

    • Author(s)
      Yano Y, Ohmori T, Hoshide S, Madoiwa S, Yamamoto K, Katsuki T, Mitsuhashi T, Mimuro J, Shimada K, Kario K, Sakata Y.
    • Journal Title

      Eur Heart J. 29

      Pages: 1729-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Unbalanced expression of ADAMTS13 and von Willebrand factor in mouse2008

    • Author(s)
      Mimuro J., Niimura M., Kashiwakura Y., Ishiwata A., Ono T., Ohmori T., Madoiwa S., Okada K., Matsuo O., Sakata Y.
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Journal Article] Antagonism of sphingosine 1-phosphate receptor-2 enhances migration of neural progenitor cells toward an area of brain.2008

    • Author(s)
      Kimura A, Ohmori T, Kashiwakura Y, Ohkawa R, Madoiwa S, Mimuro J, Shimazaki K, Hoshino Y, Yatomi Y, Sakata Y.
    • Journal Title

      Stroke. 39

      Pages: 3411-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2007

    • Author(s)
      Madoiwa S
    • Journal Title

      thromb Res. 119(2)

      Pages: 229-240

    • Data Source
      KAKENHI-PROJECT-18591084
  • [Journal Article] Silencing of a targeted protein in in vivo platelets using a lentiviral vector delivering short hairpin RNA sequence.2007

    • Author(s)
      Ohmori T, Kashiwakura Y, Ishiwata A, Madoiwa S, Mimuro J, Sakata Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol. 27

      Pages: 2266-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] 線溶系分子マーカーと線溶能の診断2007

    • Author(s)
      窓岩 清治
    • Journal Title

      日本血栓止血学会誌 18(4)

      Pages: 317-329

    • NAID

      10026115008

    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] A large deletion of the PROS1 gene in a deep vein thrombosis patient with protein S deficiency.2007

    • Author(s)
      YYin T, Takeshita S, Sato Y, Sakata T, Shin Y, Honda S, Kawasaki T, Tsuji H, Kojima T, Madoiwa S, Sakata Y, Murata M, Ikeda Y, Miyata T.
    • Journal Title

      Thromb Haemost. 98

      Pages: 783-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2007

    • Author(s)
      Madoiwa S
    • Journal Title

      Thromb Res 119(2)

      Pages: 229-240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2007

    • Author(s)
      Madoiwa S, Someya T, Hironaka M, Kobayashi H, Ohmori T, Mimuro J, Sugiyama Y, Morita T, Nishimura Y, Tarumoto T, Ozawa K, Saito K, Sakata Y.
    • Journal Title

      Thromb Res. 119

      Pages: 229-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis2007

    • Author(s)
      Madoiwa S
    • Journal Title

      Thromb Res 119(2)

      Pages: 229-240

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis2007

    • Author(s)
      Madoiwa, S
    • Journal Title

      Thromb Res 119(2)

      Pages: 229-240

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2007

    • Author(s)
      Madoiwa S, et. al.
    • Journal Title

      Thromb Res 119(2)

      Pages: 229-240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.2007

    • Author(s)
      Kimura A, Ohmori T, Ohkawa R, Madoiwa S, Mimuro J, Murakami T, Kobayashi E, Hoshino Y, Yatomi Y, Sakata Y.
    • Journal Title

      Stem Cells. 25

      Pages: 115-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2007

    • Author(s)
      Madoiwa S
    • Journal Title

      Thromb Res. 119(2)

      Pages: 229-240

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591006
  • [Journal Article] 抗血管新生物質 : アンギオスタチンの最近の進歩2007

    • Author(s)
      窓岩清治
    • Journal Title

      Annual Review 血液 2007

      Pages: 281-281

    • Data Source
      KAKENHI-PROJECT-17591006
  • [Journal Article] 悪性腫瘍と静脈血栓症2007

    • Author(s)
      窓岩 清治
    • Journal Title

      臨床血液 48(5)

      Pages: 371-376

    • NAID

      130004501103

    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Malignancy and venous thromboembolism2007

    • Author(s)
      Madoiwa S.
    • Journal Title

      Rinsho Ketsueki 48

      Pages: 371-6

    • NAID

      130004501103

    • Data Source
      KAKENHI-PROJECT-19591133
  • [Journal Article] Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation2006

    • Author(s)
      Madoiwa S
    • Journal Title

      Int J Hematol 84(5)

      Pages: 398-405

    • NAID

      10018670838

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Journal Article] Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation.2006

    • Author(s)
      Madoiwa S
    • Journal Title

      Int J Hematol. 84(5)

      Pages: 398-405

    • NAID

      10018670838

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591006
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2006

    • Author(s)
      Madoiwa S
    • Journal Title

      Thromb Res.2006 Mar 6 ; [Epub ahead of print]

    • Data Source
      KAKENHI-PROJECT-16590961
  • [Journal Article] 凝固線溶反応 I生体侵略と生体反応 総論 特集 : 基礎から学ぶ侵襲と生体反応2006

    • Author(s)
      窓岩清治
    • Journal Title

      救急医学 30(9)

      Pages: 1015-1020

    • Data Source
      KAKENHI-PROJECT-17591006
  • [Journal Article] DIC の病態と線溶2006

    • Author(s)
      窓岩清治
    • Journal Title

      日本血栓止血学会誌 17(3)

      Pages: 254-260

    • NAID

      10021258761

    • Data Source
      KAKENHI-PROJECT-17591006
  • [Journal Article] Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation2006

    • Author(s)
      Madoiwa, S
    • Journal Title

      Int J Hematol 84(5)

      Pages: 398-405

    • NAID

      10018670838

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Journal Article] Annexin 2 and hemorrhagic disorder in vascular intimal carcinomatosis.2006

    • Author(s)
      Madoiwa S
    • Journal Title

      Thromb Res.2006 Mar 6 ; [Epub ahead of print]

    • Data Source
      KAKENHI-PROJECT-17591006
  • [Journal Article] Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation.2005

    • Author(s)
      Madoiwa S
    • Journal Title

      Imt J Hematol 84(5)

      Pages: 398-405

    • NAID

      10018670838

    • Data Source
      KAKENHI-PROJECT-18591084
  • [Journal Article] Induction of immune tolerance by neonatal intravenous injection of human factor VIII in murine hemophilia A.2004

    • Author(s)
      Madoiwa S
    • Journal Title

      J Thromb Haemost. 2

      Pages: 754-762

    • NAID

      10020605038

    • Data Source
      KAKENHI-PROJECT-15591021
  • [Journal Article] Fibrinogen and fibrin degradation products by leukocyte elastase.2004

    • Author(s)
      Madoiwa S
    • Journal Title

      Nippon Rinsho. 62 Suppl 12

      Pages: 611-614

    • Data Source
      KAKENHI-PROJECT-15591021
  • [Journal Article] Induction of immune tolerance by neonatal intravenous injection of human factor VIII in murine hemophilia A.2004

    • Author(s)
      Madoiwa S
    • Journal Title

      J.Thromb.Haemost. 2(5)

      Pages: 754-762

    • NAID

      10020605038

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590961
  • [Journal Article] Induction of immune tolerance by neonatal intravenous injection of human factor VIII in murine hemophilia A.2004

    • Author(s)
      Madoiwa S
    • Journal Title

      J Thromb Haemost 2

      Pages: 754-762

    • NAID

      10020605038

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591021
  • [Journal Article] Inducation of immune tolerance by neonatal intavenous injection of human factor VIII in murine hemophilia A.2004

    • Author(s)
      Madoiwa S
    • Journal Title

      J. Thromb. haemost 2(5)

      Pages: 754-762

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590961
  • [Presentation] Regulation of plasminogen activator inhibitor -1 promotes immune tolerance to factor VIII in murine hemophilia A.2013

    • Author(s)
      Seiji Madoiwa, Tsukasa Ohmori, Toshio Miyata, Takashi Dan, Yuji Kashiwakura, Asuka Sakata, Jun Mimuro, Kiyotaka Okada, Shigeru Ueshima, Hitoshi Endo, Makoto Inoue, Mamoru Hasegawa, Osamu Matsuo, Keiya Ozawa, Yoichi Sakata
    • Organizer
      2013 Congress of Internationl Society on Thrombosis and Haemostasis
    • Place of Presentation
      Amsterdam, Netherland
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Presentation] Progression of thrombosis and hemostasis 血友病におけるインヒビター発生機序とその制御手法2013

    • Author(s)
      窓岩清治
    • Organizer
      日本血栓止血学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Presentation] 血友病Aクローンブタ2013

    • Author(s)
      柏倉裕志、三室淳、大西彰、岩元正樹、窓岩清治、淵本大一郎、鈴木俊一、鈴木美佐枝、千本昭一郎、石渡彰、安本篤史、坂田飛鳥、大森司、橋本径子、矢崎智子、坂田洋一
    • Organizer
      第35回日本血栓止血学会学術集会, (日本血栓止血学会誌)
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] REGULATION OF PLASMINOGEN ACTIVATOR INHIBITOR-1 REDUCES IMMUNE RESPONSE TO FACTOR VIII IN MURINE HEMOPHILIA A.2013

    • Author(s)
      Seiji Madoiwa, Tsukasa Ohmori, Toshio Miyata, Takashi Dan, Yuji Kashiwakura, Asuka Sakata, Jun Mimuro, Kiyotaka Okada, Shigeru Ueshima, Hitoshi Endo, Makoto Inoue, Mamoru Hasegawa, Osamu Matsuo, Keiya Ozawa, Yoichi Sakata
    • Organizer
      2013 East Asia Hemophilia Forum
    • Place of Presentation
      Seoul, South Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Presentation] Regulation of plasminogen activator inhibitor-1 promotes immune tolerance to factor VIII in murine hemophilia A2013

    • Author(s)
      Madoiwa S, Ohmori T, Kashiwakura Y, Sakata A, Mimuro J, Sakata Y
    • Organizer
      the XXIV Congress of the ISTH
    • Place of Presentation
      Amsterdam, Netherland
    • Data Source
      KAKENHI-PROJECT-24591430
  • [Presentation] 血友病の基礎と臨床-血友病インヒビター発生と免疫寛容2012

    • Author(s)
      窓岩清治
    • Organizer
      第115回日本小児科学会学術集会教育セミナー
    • Place of Presentation
      福岡市(招待)
    • Year and Date
      2012-04-20
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] FVIII遺伝子導入MSCの関節内移植は血友病Aマウスの血友病性関節症を改善する2012

    • Author(s)
      柏倉裕志,大森司,三室淳,安本篤史,石渡彰,坂田飛鳥,窓岩清治,井上誠,長谷川護,小澤敬也,坂田洋一
    • Organizer
      第34回日本血栓止血学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] Dose-respnse relationship of factor IX expression in non-human orimates using AAV8-based vector2012

    • Author(s)
      水上浩明、三室淳、塚原智典、卜部匡司、久米晃浩、大森司、窓岩清治、坂田洋一、小澤敬也
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] 第VIII因子感作血友病マウスにおけるマイクロポートを用いた連続的抗原投与モデルの構築2012

    • Author(s)
      窓岩 清治,小林 英司,坂田 飛鳥,柏倉 裕志,大森 司,三室 淳,坂田 洋一
    • Organizer
      第34回日本血栓止血学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] 血友病の基礎と臨床-血友病インヒビター発生と免疫寛容2012

    • Author(s)
      窓岩清治
    • Organizer
      第115回日本小児科学会学術集会教育セミナー
    • Place of Presentation
      福岡
    • Year and Date
      2012-04-20
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 人工多能性幹細胞を用いた新規血友病治療法に対する基礎的検討2012

    • Author(s)
      柏倉裕志、大森司、坂田飛鳥、窓岩清治、井上誠、長谷川護、三室淳、坂田洋一
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] Intra-articular injection of autologous mesenchymal stem cells ameliorates hemophilic arthropathy in factor VIII-deficient mice2011

    • Author(s)
      Kashiwakura Y, Ohmori T, Mimuro J, Yasumoto A, Ishiwata A, Sakata A, Madoiwa S, Inoue M, Hasegawa M, Watanabe N, Tatsumi K, Ohashi K, Okano T and Sakata Y
    • Organizer
      XXIII Congress of the International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] 静脈血栓塞栓症に対する経口抗凝固療法の全国調査と自己モニタリングへの展開2011

    • Author(s)
      窓岩清治
    • Organizer
      第7回肺血栓塞栓症研究会
    • Place of Presentation
      宇都宮市
    • Year and Date
      2011-11-01
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Degradation of cross-linked fibrin by leukocyte elastase as alternative pathway for plasmin-mediated fibrinolysis in sepsis-induced disseminated intravascular coagulation2011

    • Author(s)
      Madoiwa S., et al.
    • Organizer
      23rd Congress of the International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Kyoto
    • Year and Date
      2011-07-26
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 血友病インヒビター発生に関する考察-動物モデルを用いた免疫寛容誘導法の研究-2011

    • Author(s)
      窓岩清治
    • Organizer
      血友病PUPs研究会
    • Place of Presentation
      東京(招待)
    • Year and Date
      2011-09-03
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 線溶系から捉えたDICの病態-血栓溶解をどのように把握するか-2011

    • Author(s)
      窓岩清治
    • Organizer
      第13回大阪DIC研究会特別講演
    • Place of Presentation
      大阪市(招待)
    • Year and Date
      2011-06-22
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Intra-articular injection of autologous mesenchymal stem cells ameliorates hemophilic arthropathy in factor VIII-deficient mice.2011

    • Author(s)
      Y. Kashiwakura., T.,Ohmori., J. Mimuro., A.,Yasumoto., Akira,Ishiwata., A.,Sakata., S.Madoiwa., M.Inoue., M.,Hasegawa., N.,Watanabe.,K.Tatsumi., K.Ohashi., T.Okano., Y.Sakata
    • Organizer
      ISTH2011.XXIII Congress of the International Society on Thrombosis and Haemostasis.
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-23591426
  • [Presentation] 造血器悪性腫瘍とDIC-その病態と診断-2011

    • Author(s)
      窓岩清治
    • Organizer
      第73回日本血液学会学術集会コーポレートセミナー
    • Place of Presentation
      名古屋市(招待)
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Leukocyte elastase as an alternative pathway for fibrinolysis.2011

    • Author(s)
      Seiji, Madoiwa., Hideyuki, Tanaka., Yutaka, Nagahama., Atsushi, Yasumoto., Asuka, Sakata., Yuji, Kashiwakura., Tsukasa, Ohmori., Jun, Mimuro., Yoichi, Sakata.
    • Organizer
      57th Annual SSC Meetin
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-23591426
  • [Presentation] Leukocyte elastase contributes to degradation of cross-linked fibrin in sepsis-induced DIC2011

    • Author(s)
      Madoiwa S., et al
    • Organizer
      The 73rd Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2011-10-11
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 線溶系から捉えたDICの病態-血栓溶解をどのように把握するか-2011

    • Author(s)
      窓岩清治
    • Organizer
      第13回大阪DIC研究会特別講演
    • Place of Presentation
      大阪市
    • Year and Date
      2011-06-22
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] DICの病態-血栓溶解機構を把握する臨床的意義-2011

    • Author(s)
      窓岩清治
    • Organizer
      第9回北陸血栓研究会特別講演
    • Place of Presentation
      金沢市(招待)
    • Year and Date
      2011-10-29
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Leukocyte elastase as an alternative pathway for fibrinolysis2011

    • Author(s)
      Madoiwa S., et al.
    • Organizer
      57th Annual SSC Meeting
    • Place of Presentation
      Kyoto
    • Year and Date
      2011-07-24
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] DICの病態と線溶系2011

    • Author(s)
      窓岩清治
    • Organizer
      2011日本DIC研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-01-29
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 敗血症における白血球エラスターゼの作用2011

    • Author(s)
      窓岩清治
    • Organizer
      第5回SIRS-DIC研究会
    • Place of Presentation
      宇都宮
    • Year and Date
      2011-07-01
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 血友病インヒビター発生に関する考察-動物モデルを用いた免疫寛容誘導法の研究-2011

    • Author(s)
      窓岩清治
    • Organizer
      血友病PUPs研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-09-03
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] DICの病態-血栓溶解機構を把握する臨床的意義2011

    • Author(s)
      窓岩清治
    • Organizer
      第9回北陸血栓研究会特別講演
    • Place of Presentation
      金沢
    • Year and Date
      2011-10-29
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Leukocyte elastase as an alternative pathway for fibrinolysis2011

    • Author(s)
      Madoiwa S., et al
    • Organizer
      57th Annual SSC Meeting
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2011-07-24
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] サイトカインストーム、特に敗血症DICにおける血栓溶解と白血球エラスターゼ2011

    • Author(s)
      窓岩清治
    • Organizer
      第5回サイトカインストーム研究会
    • Place of Presentation
      宇都宮市
    • Year and Date
      2011-02-04
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 敗血症における白血球エラスターゼの作用2011

    • Author(s)
      窓岩清治
    • Organizer
      第5回SIRS-DIC研究会
    • Place of Presentation
      宇都宮市
    • Year and Date
      2011-07-01
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 造血器悪性腫瘍とDIC-その病態と診断2011

    • Author(s)
      窓岩清治
    • Organizer
      第73回日本血液学会学術集会コーポレートセミナー
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-14
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Degradation of cross-linked fibrin by leukocyte elastase as alternative pathway for plasmin-mediated fibrinolysis in sepsis-induced disseminated intravascular coagulation2011

    • Author(s)
      Madoiwa S., et al
    • Organizer
      23rd Congress of the International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2011-07-26
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Intra-articular injection of autologous mesenchymal stem cells ameliorates hemophilic arthropathy in factor VIII-deficient mice2011

    • Author(s)
      Kashiwakura Y, Ohmori T, Mimuro J, Yasumoto A, Ishiwata A, Sakata A, Madoiwa S, Inoue M, Hasegawa M, Watanabe N, Tatsumi K, Ohashi K, Okano T, Sakata Y
    • Organizer
      ISTH2011.XXIII Congress of the International Society on Thrombosis and Haemostasis.57^<th> Annual SSC Meeting
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] Leukocyte elastase contributes to degradation of cross-linked fibrin in sepsis-induced DIC2011

    • Author(s)
      Madoiwa S., et al.
    • Organizer
      The 73rd Annual Meeting of the Japanese Society of Hematology
    • Place of Presentation
      Nagoya
    • Year and Date
      2011-10-15
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Silencing of A targeted protein in platelets using A lentiviral vector delivering short hairpin RNA sequence.2010

    • Author(s)
      大森司,柏倉裕志, 石渡彰, 窓岩清治, 三室淳, 坂田洋一
    • Organizer
      第16回日本遺伝子治療学会学術集会
    • Place of Presentation
      宇都宮
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] Liver-restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII-deficient mice.2010

    • Author(s)
      Jun Mimuro, Akira Ishiwata, Hiroaki Mizukami, Yuji Kashiwakura, Katsuhiro Takano, Tsukasa Ohmori, Seiji Madoiwa, Keiya Ozawa, Yoichi Sakata
    • Organizer
      第16回日本遺伝子治療学会学術集会
    • Place of Presentation
      宇都宮
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] Robust and sustained factor IX expression following IV injection of AAV8-based vectors in magaques.2010

    • Author(s)
      水上浩明、三室淳、石渡彰、八木洋也、大森司、窓岩清治、卜部匡司、久米晃浩、坂田洋一、小澤敬也
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] マイクロポート植え込み成体血友病Aマウスを用いた持続的第VIII因子刺激に対する免疫応答能の解析2010

    • Author(s)
      窓岩清治
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 血栓溶解の基礎と血栓溶解療法のガイドライン:血栓溶解薬-特徴と保険適応2010

    • Author(s)
      窓岩清治
    • Organizer
      第5回日本血栓止血学会学術標準化委員会血栓溶解部会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] レンチウィルスベクターを用い た血小板標的遺伝子導入法の開発(シ ンポジウム)2010

    • Author(s)
      大森司、窓岩清治、三室淳、坂田洋一
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] DICの病態・診断・治療~新規&分子マーカーの意義~敗血症DICにおける白血球エラスターゼによる血栓溶解の臨床的意義2010

    • Author(s)
      窓岩清治
    • Organizer
      第5回日本血栓止血学会学術標準化委員会血栓溶解部会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 敗血症における白血球エラスターゼの造血制御機構2010

    • Author(s)
      窓岩清治、, 他
    • Organizer
      第33回日本血栓止血学会学術集会
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] DICの病態・診断・治療~新規 & 分子マーカーの意義~敗血症DICにおける白血球エラスターゼによる血栓溶解の臨床的意義2010

    • Author(s)
      窓岩清治、, 他
    • Organizer
      第5回日本血栓止血学会学術標準化委員会DIC部会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Platelet-directed gene modification by lentiviral vector:Application to therapies for inherited bleeding disorders and research into platelet signal. シンポジウム2010

    • Author(s)
      大森司、窓岩清治、三室淳、坂田洋一
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] DICの病態と診断-線溶系の観点から-2010

    • Author(s)
      窓岩清治
    • Organizer
      第5回日本血栓止血学会学術標準化委員会ランチョンセミナー
    • Place of Presentation
      東京
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Impact ofacute cellular rejection onbiomarkers in liver transplantation2010

    • Author(s)
      三室淳、水田耕一、川野陽一、菱川修司、浜野明栄、柏倉裕志、石渡彰、坂田飛鳥、安本篤史、大森司、窓岩清治、河原崎秀雄、坂田洋一
    • Organizer
      第33回日本血栓止血学会学術集会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 非ヒト霊長類を用いた血友病B 遺伝子治療研究:末梢静脈投与AAV8 ベクターによる第IX 因子遺伝子導入2010

    • Author(s)
      石渡彰、三室淳、水上浩明、小野文子、安本篤史、坂田飛鳥、柏倉裕志、大森司、窓岩清治、久米晃啓、保富康宏、小澤敬也、坂田洋一
    • Organizer
      第33回日本血栓止血学会学術集会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] Promoter selection formuscle-directed self-complementary AAV toward hemophilia B gene therapy.2010

    • Author(s)
      久米晃浩、八木洋也、水上浩明、卜部匡司、塚原智典、石渡彰、三室淳、窓岩清治、大森司、坂田洋一、小澤敬也
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] Vinculin is indispensadle forrepopulation by hematopoietic stem cells.2010

    • Author(s)
      Tsukasa Ohmori, Yuji Kashiwakura, Akira Ishiwata, Seiji Madoiwa, Jun Mimuro, Yusuke Furukawa, Yoichi Sakata
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] Vinculin は巨核球分化とintegrin αIIb3 の活性化に関与する2010

    • Author(s)
      大森司、柏倉裕志、石渡彰、坂田飛鳥、安本篤史、窓岩清治、三室淳、本田繁則、宮田敏行、坂田洋一
    • Organizer
      第33回日本血栓止血学会学術集会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 敗血症DICにおける血栓溶解機構のモニタリング2010

    • Author(s)
      窓岩清治
    • Organizer
      第11回侵襲と生体反応研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-02-27
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] The chicken hypersensitive site-4 chromatin insulator sequence protects clonal domina of hematopoietic stem cells transduced with a self-inactivating SIV vector in platelet-directed gene therapy.2010

    • Author(s)
      Tsukasa Ohmori, Yuji Kashiwakura, Akira Ishiwata, Seiji Madoiwa, Eiji Akiba, Mamoru Hasegawa, Jun Mimuro, Keiya Ozawa, Yoichi Sakata
    • Organizer
      第16回日本遺伝子治療学会学術集会
    • Place of Presentation
      宇都宮
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 担癌患者における血栓塞栓症2010

    • Author(s)
      窓岩清治
    • Organizer
      第8回日本臨床腫瘍学会学術集会教育講演
    • Place of Presentation
      東京
    • Year and Date
      2010-03-19
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 血栓溶解の基礎と血栓溶解療法のガイドライン-血栓溶解薬-特徴と保険適応2010

    • Author(s)
      窓岩清治
    • Organizer
      第5回日本血栓止血学会学術標準化委員会血栓溶解部会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] マイクロポート植え込み成体血友病Aマウスを用いた第VIII因子頻回刺激に対する免疫応答能の解析2010

    • Author(s)
      窓岩清治、, 他
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] マイクロポート植え込み成体血友病 A マウスを用いた持続的第VIII 因子 刺激に対する免疫応答能の解析2010

    • Author(s)
      窓岩清治、小林英司、石渡彰、柏倉裕志、大森司、三室淳、坂田洋一
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] Choice of small-sized promother for AAV-medlated factor IX expression in skeletal muscle.2010

    • Author(s)
      Akihiro Kume, Hiroya Yagi, Hiroaki Mizukami, Masashi Urabe, Tomonori Tsukahara, Akira Ishiwata, Jun Mimuro, Seiji Madoiwa, Tsukasa Ohmori, Yoichi Sakata, Keiya Ozawa
    • Organizer
      第16回日本遺伝子治療学会学術集会
    • Place of Presentation
      宇都宮
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 非ヒト霊長類を用いた血友病A伝子治療研究に向けたヒトBDDFVIII特異的検出法の確立2010

    • Author(s)
      柏倉裕志、三室淳、石渡彰、安本篤史、坂田飛鳥、大森司、窓岩清治、水上浩明、小野文子、小澤敬也、坂田洋一
    • Organizer
      第33回日本血栓止血学会学術集会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] GPIba 遺伝子近傍のクロマチンインスレーター配列の同定2009

    • Author(s)
      大森司、青木慎也、Thasinas Dissayabutra、石渡彰、柏倉裕志、窓岩清治、秋葉栄治、長谷川護、三室淳、坂田洋一
    • Organizer
      第32回日本血栓止血学会学術集会
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 感染症DICを考慮した現厚生労働省診断基準の検討2009

    • Author(s)
      窓岩清治
    • Organizer
      第4回日本血栓止血学会学術標準化委員会シンポジウム
    • Place of Presentation
      東京都
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] DICと線溶病態2009

    • Author(s)
      窓岩清治
    • Organizer
      第9回群馬血栓止血研究会
    • Place of Presentation
      高崎市
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 線溶系からDICを捉える2009

    • Author(s)
      窓岩清治
    • Organizer
      第20回九州血管血栓フォーラム
    • Place of Presentation
      熊本市
    • Year and Date
      2009-11-07
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Intrathymic administration of Factor VIII results in immune tolerance by induction of Factor VIII-specific regulatory T cells in murine hemoph ilia A2009

    • Author(s)
      窓岩清治
    • Organizer
      XXII Congress of International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] DICにおける線溶系のモニタリング-その臨床的意義を考える2009

    • Author(s)
      窓岩清治
    • Organizer
      第10回日本検査血液学会学術集会セミナー
    • Place of Presentation
      山梨
    • Year and Date
      2009-07-04
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 敗血症における凝固線溶系異常2009

    • Author(s)
      窓岩清治
    • Organizer
      第32回日本血栓止血学会学術集会
    • Place of Presentation
      北九州
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 地域医療における血栓症・出血性疾患の診療2009

    • Author(s)
      窓岩清治
    • Organizer
      第19回福井県地域医療学術集会
    • Place of Presentation
      福井県美浜町
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Development of immune tolerance induction by intrathymic administration of Factor VIII in murine hemophilia A2009

    • Author(s)
      窓岩清治
    • Organizer
      2009 East Asia Hemophilia Forum
    • Place of Presentation
      Kitakyushu, Japan
    • Year and Date
      2009-06-07
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Development of immune tolerance induction by intrathymic administration of Factor VIII in murine hemophilia A2009

    • Author(s)
      Madoiwa S., et al
    • Organizer
      2009 East Asia Hemophilia Forum
    • Place of Presentation
      Kitakyushu
    • Year and Date
      2009-06-07
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 敗血症における凝固線溶系異常2009

    • Author(s)
      窓岩清治
    • Organizer
      第32回日本血栓止血学会学術集会 日本血栓止血学会・日本救急医学会ジョイントシンポジウム
    • Place of Presentation
      北九州
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 敗血症における白血球エラスターゼの造血制御機構2009

    • Author(s)
      窓岩清治
    • Organizer
      第7回血液・血管フォ-ラム
    • Place of Presentation
      北九州
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 感染症DICを考慮した現厚生労働省診断基準の検討2009

    • Author(s)
      窓岩清治
    • Organizer
      第4回日本血栓止血学会学術標準化委員会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 悪性腫瘍と凝固線溶系2009

    • Author(s)
      窓岩清治
    • Organizer
      第47回東北血栓止血研究会
    • Place of Presentation
      福島
    • Year and Date
      2009-09-12
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 線溶系からDICを捉える2009

    • Author(s)
      窓岩清治
    • Organizer
      第20回九州血管血栓フォーラム
    • Place of Presentation
      熊本
    • Year and Date
      2009-11-07
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] Intrathymic administration of Factor VIII results in immune tolerance by induction of Factor VIII-specific regulatory T cells in murine hemophilia A2009

    • Author(s)
      Madoiwa S., et al
    • Organizer
      22nd Congress of the International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 高純度AAV8、AAV9 ベクター精製法ノ確立2009

    • Author(s)
      石渡彰、三室淳、柏倉裕志、大森司、窓岩清治、水上浩明、久米晃啓、小澤敬也、坂田洋一
    • Organizer
      第32回日本血栓止血学会学術集会
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] DICにおける線溶系のモニタリング-その臨床的意義を考える-2009

    • Author(s)
      窓岩清治
    • Organizer
      第10回日本検査血液学会学術集会
    • Place of Presentation
      甲府市
    • Year and Date
      2009-07-04
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 悪性腫瘍と凝固線溶系2009

    • Author(s)
      窓岩清治
    • Organizer
      第47回東北血栓止血研究会
    • Place of Presentation
      福島市
    • Year and Date
      2009-09-12
    • Data Source
      KAKENHI-PROJECT-21591249
  • [Presentation] 敗血症DICにおける血栓溶解機構のモニタリングとその臨床的意義2009

    • Author(s)
      窓岩清治、田中英之、松浦司郎、大森 司、三室 淳、坂田洋一青木慎也
    • Organizer
      第9回TTMフォーラム
    • Place of Presentation
      東京
    • Year and Date
      2009-03-07
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] 血小板への遺伝子発現増強を目的としたGPIba プロモーターの改変2009

    • Author(s)
      Thasinas Dissayabutra、大森司、青木慎也、石渡彰、柏倉裕志、窓岩清治、秋葉栄治、長谷川護、三室淳、坂田洋一
    • Organizer
      第32回日本血栓止血学会学術集
    • Place of Presentation
      北九州
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 癌患者と静脈血栓症-癌と凝固線溶系-敗血症DICにおける白血球エラスターゼによる血栓溶解機構の解析2008

    • Author(s)
      窓岩清治
    • Organizer
      肺塞栓症研究会ランチョンセミナー
    • Place of Presentation
      東京
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] AAV ベクターを用いた遺伝子導入法と免疫反応 血友病B に関する検討を中心に2008

    • Author(s)
      水上浩明, 八木洋也, 三室淳, 石渡彰, 窓岩清治, 卜部匡司, 久米晃啓, 坂田洋一, 小澤敬也
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 敗血症DTCにおける白血球エラスターゼによる血栓溶解機構の解析2008

    • Author(s)
      窓岩清治
    • Organizer
      第31回日本血栓止血学会学術集
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 異常第VIII 因子遺伝子正常化による血友病A 遺伝子治療の試み2008

    • Author(s)
      柏倉裕志, 三室淳, 石渡彰, 山中一央, 土海桃子, 青木慎也, 大森司, 窓岩清治, 坂田洋一
    • Organizer
      第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] Cancer associated thrombosisの診断と治療2008

    • Author(s)
      窓岩清治
    • Organizer
      日本血液学会(シンポジウム)
    • Place of Presentation
      京都
    • Year and Date
      2008-10-10
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] Regulation of plasminogen activator-plasmin system and inflammation.2008

    • Author(s)
      窓岩清治
    • Organizer
      第31回日本血栓止血学会学術集
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 敗血症DICにおける白血球エラスターゼによる血栓溶解機構の解析2008

    • Author(s)
      窓岩清治
    • Organizer
      第31回日本血栓止血学会学術集
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] 感染症DICを考慮した厚生労働省診断基準の改訂試案2008

    • Author(s)
      窓岩清治 坂田洋一
    • Organizer
      日本血栓止血学会学術標準化委員会2008(シンポジウム)
    • Place of Presentation
      東京
    • Year and Date
      2008-02-16
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] 非ヒト霊長類モデルにおける血友病B 遺伝子治療の基礎的検討2008

    • Author(s)
      石渡彰, 三室淳, 水上浩明, 小野文子,柏倉裕志, 大森司, 諏合輝子, 窓岩清治, 保富康宏, 小澤敬也, 坂田洋一
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] Regulation of plasminogen activator - plasmin system and inflammation2008

    • Author(s)
      Seiji Madoiwa, Takayuki Sejima, Jun Mimuro, Tsukasa Ohmori, Yoichi Sakata
    • Organizer
      31st Congress of the Japanese Society on Thrombosis and Haemostasis (President Symposium)
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2008-11-21
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] エンドトキシン症における血栓性微小血管障害の発症機序の解析2008

    • Author(s)
      柏倉裕志, 三室淳, 新村真則, 小野智子, 石渡彰, 土海桃子, 大森司, 窓岩清治, 岡田清孝, 松尾理, 坂田洋一
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 血小板への活性化型血液凝固第VII 因子の発現による血友病遺伝子治療2008

    • Author(s)
      大森司, 石渡彰, 柏倉裕志, 窓岩清治, 鈴木英紀, 見供克之, 長谷川護,三室淳, 坂田洋一
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 静脈血栓塞栓症予防のゆくえ-第二ステージ 抗凝固療法2008

    • Author(s)
      窓岩清治
    • Organizer
      日本麻酔科学会第55回学術集会(シンポジウム)
    • Place of Presentation
      横浜
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] Regulation of plasminogen activator-plasmin system and inflammation.2008

    • Author(s)
      窓岩清治
    • Organizer
      第31回日本血栓止血学会学術集
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] DICをどう捉えるか-プロテアーゼによる血栓溶解と病態2008

    • Author(s)
      窓岩清治
    • Organizer
      DICをどう捉えるか-プロテアーゼによる血栓溶解と病態
    • Place of Presentation
      札幌
    • Year and Date
      2008-11-08
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] Regulation of plasminogen activator-plasmin system and inflammation.2008

    • Author(s)
      窓岩清治, 三室淳, 大森司, 坂田洋一
    • Organizer
      第31回日本血栓止血学会学術集会(シンポジウム)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20591155
  • [Presentation] 敗血症DICにおける白血球エラスターゼによる血栓溶解機構の解析2008

    • Author(s)
      窓岩清治,土海桃子,柏倉裕志,石渡 彰,大森 司,諏合輝子,三室 淳,田中英之、松浦司郎,坂田洋一
    • Organizer
      第31回日本血栓止血学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-22
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] 胸腺組織を標的とした血友病Aインヒビター産生制御の基礎的検討2007

    • Author(s)
      窓岩清治,山内忠彦,小林英司,柏倉裕志,石渡 彰,大森 司,三室 淳,坂田 洋一
    • Organizer
      第69回日本血液学会・第49回日本臨床血液学会合同総会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] マウスモデルを用いた血友病Aインヒビター産生制御の検討2007

    • Author(s)
      窓岩清治
    • Organizer
      第30回日本血栓止血学会学術集会(シンポジウム)
    • Place of Presentation
      三重
    • Year and Date
      2007-11-15
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] サイトカン・ストーム、特に敗血症における白血球エラスターゼの役割2007

    • Author(s)
      窓岩清治
    • Organizer
      第1回サイトカイン・ストーム研究会
    • Place of Presentation
      宇都宮
    • Year and Date
      2007-03-29
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] Induction of Factor VIII Specific Unresponsiveness by Intrathymic Factor VIII Injection in Murine Hemophilia A.2007

    • Author(s)
      Seiji Madoiwa, Tadahiko Yamauchi, Eiji Kobayashi, Yoji Hakamata, Yuji Kashiwakura, Akira Ishiwata, Tsukasa Ohmori, Jun Mimuro, Yoichi Sakata
    • Organizer
      XXIst Congress of the International Society on Thrombosis and Haemostasis
    • Place of Presentation
      Geneva, Switzerland
    • Year and Date
      2007-07-08
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] PAI-1は敗血症DICの生命予後を規定する2007

    • Author(s)
      窓岩清治,布宮 伸,大森 司,三室 淳,坂田洋一
    • Organizer
      第8回日本検査血液学会
    • Place of Presentation
      福井
    • Year and Date
      2007-07-21
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] Induction of factor VIII specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A2007

    • Author(s)
      Madoiwa S
    • Organizer
      XXI ISTH Congress(21回国際血栓止血学会)
    • Place of Presentation
      ジュネーブ
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Presentation] Induction of factor VIII specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A.2007

    • Author(s)
      Madoiwa S
    • Organizer
      XXI ISTH Congress(21回国際血栓止血学会)
    • Place of Presentation
      ジュネーブ(スイス)
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Presentation] Induction of factor VIII specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A.2007

    • Author(s)
      Madoiwa S
    • Organizer
      XXI ISTH Congress(21回国際血栓止血学会)
    • Place of Presentation
      ジュネーブ(スイス)
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] PAI-1は敗血症DICの生命予後を規定する2007

    • Author(s)
      窓岩 清治
    • Organizer
      第8回日本検査血液学会学術集会
    • Place of Presentation
      福井
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Presentation] Plasminogen activator inhibitor 1 promotes a poor prognosis in sepsis-induced disseminated intravascular coagulation2007

    • Author(s)
      Madoiwa, S
    • Organizer
      The 8th Congress of Japanese Society for Laboratory Hematology
    • Place of Presentation
      Fukui
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Presentation] Plasminogen functions inhibitory to sepsis-induced organ injuries by modulation of neutrophil adherence activity2007

    • Author(s)
      Madoiwa, S
    • Organizer
      The 30th Congress of Japanese Society on Thrombosis and Haemostasis
    • Place of Presentation
      Shima
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Presentation] Induction of factor VIII specific unresponsiveness by intrathymic factor VIII injection in murine hemophilia A2007

    • Author(s)
      Madoiwa, S
    • Organizer
      XXI ISTH Congress
    • Place of Presentation
      Geneva
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Presentation] 血栓溶解機構からみたDICの病態と診断2007

    • Author(s)
      窓岩清治
    • Organizer
      第10回日本臨床救急医学会総会ランチョンセミナー
    • Place of Presentation
      神戸
    • Year and Date
      2007-05-17
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] フィブリン分解産物の標準化に向けて2007

    • Author(s)
      窓岩清治,大森 司,三室 淳,坂田洋一,北島 勲,岡田清孝,上嶋 繁,松尾 理,一瀬白帝,内山真一郎,朝倉英策,江口 豊,浦野哲盟,山本晃士,桜井錠治、馬場光広
    • Organizer
      日本血栓止血学会学術標準化委員会2007(シンポジウム)
    • Place of Presentation
      東京
    • Year and Date
      2007-02-17
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] Annexin 2 mediated fibrinolysis induces fatal hemorrhagic disorder in transitional cell carcinoma with vascular intimal carcinomatosis.2007

    • Author(s)
      Seiji Madoiwa, Tsukasa Ohmori, Jun Mimuro, Yoichi Sakata
    • Organizer
      1st Japanese-Polish - German Joint Meeting on Coagulation and Fibrinolysis
    • Place of Presentation
      Dresden, Germany
    • Year and Date
      2007-07-13
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] プラスミノゲンは白血球の接着活性を制御し、敗血症における臓器障害を回避させる2007

    • Author(s)
      窓岩 清治
    • Organizer
      第30回日本血栓止血学会学術集会
    • Place of Presentation
      志摩
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Presentation] プラスミノゲンは白血球の接着活性を制御し、敗血症における臓器障害を回避させる2007

    • Author(s)
      窓岩清治,新村真則,土海桃子,柏倉裕志,石渡 彰,牧野伸子,大森 司,諏合輝子,三室 淳,坂田洋一、岡田清孝,上嶋 繁,松尾 理
    • Organizer
      第30回日本血栓止血学会学術集会
    • Place of Presentation
      三重
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] 敗血症DICにおけるPAI-1と生命予後との関係2007

    • Author(s)
      窓岩清治,布宮 伸,小野智子,大森 司,三室 淳,坂田洋一
    • Organizer
      第1回SIRS-DIC研究会
    • Place of Presentation
      宇都宮
    • Year and Date
      2007-06-22
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] PAI-1は敗血症DICの生命予後を規定する2007

    • Author(s)
      窓岩 清治
    • Organizer
      第8回日本検査血液学会学術集
    • Place of Presentation
      福井
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] 線溶系からみた血栓性疾患の病態-プラスミンと白血球エラスターゼの血栓溶解への関わり-2007

    • Author(s)
      窓岩清治
    • Organizer
      第30回日本血栓止血学会学術集会ランチョンセミナー
    • Place of Presentation
      三重
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19591133
  • [Presentation] プラスミノゲンは白血球の接着活性を制御し、敗血症における臓器障害を回避させる2007

    • Author(s)
      窓岩 清治
    • Organizer
      第30回日本血栓止血学会学術集会
    • Place of Presentation
      三重
    • Data Source
      KAKENHI-PROJECT-18591084
  • [Presentation] Development of cell-based therapy for treating hemophilic arthropathy by local injection of transduced MSCs

    • Author(s)
      Ohmori T, Kashiwakura Y, Mimuro J, Yasumoto A, Ishiwata A, Sakata A, Madoiwa S, Inoue M, Hasegawa M, Ozawa K, and Sakata Y
    • Organizer
      第35回日本血栓止血学会学術集会
    • Place of Presentation
      山形
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] 血友病Aクローンブタ

    • Author(s)
      柏倉裕志,三室 淳,大西 彰,岩本正樹,窓岩清治,渕本大一郎,鈴木俊一,鈴木美佐枝,千本昭一郎,石渡 彰,安本 篤,坂田飛鳥,大森 司,橋本経子,矢崎智子,坂田洋一
    • Organizer
      第35回日本血栓止血学会学術集会
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-23591427
  • [Presentation] 第FVIII因子感作血友病Aマウスにおけるマイクロボードを用いた連続的抗原投与モデルの構築

    • Author(s)
      窓岩清治
    • Organizer
      第34回日本血栓止血学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591426
  • [Presentation] A role of plasminogen activator-plasmin system for the immune in murine hemophilia A

    • Author(s)
      窓岩清治
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591426
  • [Presentation] Overexpression of factor VII ameliorates bleeding diathesis of FVIII-deficient mice with inhibitors

    • Author(s)
      安本 篤史、窓岩 清治、柏倉 裕志、石渡 彰、大森 司、水上 浩明 、小澤 敬也、坂田 洋一 、三室 淳
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23591427
  • 1.  MIMURO Jun (10221607)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 61 results
  • 2.  SAKATA Youichi (40129028)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  OHMORI Tsukasa (70382843)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 104 results
  • 4.  KOBAYASHI Eiji (00245044)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 8 results
  • 5.  SUGO Teruko (60183844)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  MATSUDA Michio (50048980)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  MIZUKAMI Hiroaki (20311938)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  ISHIKAWA Kotaro (60347987)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ISHIMURA Keiichi (00010471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ENDO Hitoshi (50221817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  中村 謙一 (10448855)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  西村 智 (80456136)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  朝倉 伸司 (70245033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KIMURA Atsushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  小澤 敬也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 16.  市川 真澄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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