HIGAI Koji 桧貝孝慈

… Alternative Names

桧貝孝慈ヒガイコウジ

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Researcher Number	70297711
Other IDs
Affiliation (Current)	2025: 東邦大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 東邦大学, 薬学部, 教授 2011 – 2018: 東邦大学, 薬学部, 准教授 2007 – 2010: Toho University, 薬学部, 講師
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator NK細胞 / 肝細胞がん / NCRs / NKG2D / CD94 / 分子標的薬 / 糖鎖依存性細胞傷害 / 細胞傷害 / 糖鎖リガンド / NCR … More / Lectin / sialyl Lewis X / バイオマーカー / NK依存性細胞傷害 / ベバシズマブ / アテゾリズマブ / 腫瘍免疫 / 進行性肝がん / 糖鎖依存性細胞障害 / ソラフェニブ / 転写制御 / 局在化 / IL-2 / NKG2A / NKG2s / KLRs / 多糖類 / レクチン受容体 / シアル酸 / Polysaccharides / heparin / sialyl lewis X / Killer LRs / IL-6 / IL-1β / promoter / Fucosyltransferase VI / α2, 3-sialic acid / 臨床化学 Less

肝細胞がんに対する抗腫瘍免疫モジュレーターの開発と新規バイオマーカーの臨床応用Principal Investigator
- Principal Investigator
  
  桧貝孝慈
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Toho University
Development of remodeling medicine on hepatocellular carcinoma for inducible NK dependent cytotoxicity by molecular target medicinePrincipal Investigator
- Principal Investigator
  
  HIGAI Koji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Toho University
Regulation of glycan-dependent cytotoxicity against advanced HCC by the molecular target drugPrincipal Investigator
- Principal Investigator
  
  HIGAI Koji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Toho University
The Mechanism of Glycan-dependent Cytotoxicity by NK cellsPrincipal Investigator
- Principal Investigator
  
  HIGAI Koji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Toho University
Regulation of NK cell activation by glycanPrincipal Investigator
- Principal Investigator
  
  HIGAI Koji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Toho University
Glycan ligands of killer lectin-like receptors and regulation of NK functionsPrincipal Investigator
- Principal Investigator
  
  HIGAI Koji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Toho University
biosynthesis regulation of sialyl lewis X in sera and its participation in immune responsePrincipal Investigator
- Principal Investigator
  
  HIGAI Koji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Toho University

[Book] 「5.5組換え蛋白質:組換え蛋白質の発現と糖鎖修飾」「バイオマテリアルの基礎」分担2010
- Author(s)
  桧貝孝慈、松本宏治郎
- Publisher
  日本医学館
- Data Source
  KAKENHI-PROJECT-21790544
[Book] 「5.5 組換え蛋白質:組換え蛋白質の発現と糖鎖修飾」「バイオマテリアルの基礎」分担2010
- Author(s)
  桧貝孝慈、松本宏次郎
- Total Pages
  259
- Publisher
  日本医学館
- Data Source
  KAKENHI-PROJECT-21790544
[Book] 「組換え蛋白質:組換え蛋白質の発現と糖鎖修飾」バイオマテリアル-生体材料-特集「異分野融合のためのバイオマテリアルの基礎PART6」Vol.272009
- Author(s)
  桧貝孝慈、松本宏治郎
- Publisher
  日本医学館
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] Remaining Issues Related to Serum Cytokines in Patients with Unresectable Hepatocellular Carcinoma Treated by Atezolizumab plus Bevacizumab Combination Treatment2024
- Author(s)
  Nagai Hidenari、Mukozu Takanori、Matsui Teppei、Mohri Kunihide、Nagumo Hideki、Yoshimine Naoyuki、Kobayashi Kojiro、Ogino Yu、Daido Yasuko、Wakui Noritaka、Momiyama Koichi、Matsuda Takahisa、Igarashi Yoshinori、Higai Koji
- Journal Title
  
  Oncology
  
  Volume: 1 Issue: 10 Pages: 1-13
- DOI
  10.1159/000537965
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06288
[Journal Article] Importance of Atezolizumab Plus Bevacizumab Combination Treatment as First-line Therapy for Immunological Changes in Patients With Unresectable Hepatocellular Carcinoma2023
- Author(s)
  KOBAYASHI KOJIRO、NAGAI HIDENARI、MATSUI TEPPEI、MATSUDA TAKAHISA、HIGAI KOJI
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 10 Pages: 4601-4609
- DOI
  10.21873/anticanres.16654
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06288
[Journal Article] Lenvatinib Might Induce Activation of Host Immunity in Patients with Hepatocellular Carcinoma2022
- Author(s)
  Nagai Hidenari、Mukozu Takanori、Kobayashi Kojiro、Nogami Akira、Nagumo Hideki、Mohri Kunihide、Watanabe Go、Amanuma Makoto、Yoshimine Naoyuki、Ogino Yu、Matsui Daigo、Daido Yasuko、Matsukiyo Yasushi、Matsui Teppei、Wakui Noritaka、Momiyama Koichi、Higai Koji、Matsuda Takahisa
- Journal Title
  
  Oncology
  
  Volume: 101 Issue: 1 Pages: 32-40
- DOI
  10.1159/000527306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07141
[Journal Article] Adaptation of lenvatinib treatment in patients with hepatocellular carcinoma and portal vein tumor thrombosis2021
- Author(s)
  Mukozu Takanori、Nagai Hidenari、Matsui Daigo、Mohri Kunihide、Watanabe Go、Yoshimine Naoyuki、Amanuma Makoto、Kobayashi Kojiro、Ogino Yu、Matsukiyo Yasushi、Matsui Teppei、Daido Yasuko、Wakui Noritaka、Shinohara Mie、Momiyama Koichi、Higai Koji、Igarashi Yoshinori
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 89 Issue: 1 Pages: 11-20
- DOI
  10.1007/s00280-021-04359-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07141
[Journal Article] Tivantinib Decreases Hepatocyte Growth Factor-Induced BCRP Expression in Hepatocellular Carcinoma HepG2 Cells2020
- Author(s)
  Kobayashi Kojiro、Higai Koji、Mukozu Takanori、Matsui Daigo、Amanuma Makoto、Yoshimine Naoyuki、Ogino Yu、Matsui Teppei、Wakui Noritaka、Shinohara Mie、Momiyama Koichi、Daido Yasuko、Nagai Hidenari、Igarashi Yoshinori
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 9 Pages: 1421-1425
- DOI
  10.1248/bpb.b19-01100
- NAID
  130007894898
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07141
[Journal Article] Influence of Sorafenib on Host Immunity in Patients with Liver Cirrhosis With Advanced Hepatocellular Carcinoma Stratified by Etiology2019
- Author(s)
  NAGAI HIDENARI、MUKOZU TAKANORI、KOBAYASHI KOJIRO、AMANUMA MAKOTO、YOSHIMINE NAOYUKI、OGINO YU、MATSUI DAIGO、DAIDO YASUKO、MATSUKIYO YASUSHI、MATSUI TEPPEI、WAKUI NORITAKA、MOMIYAMA KOICHI、SHINOHARA MIE、HIGAI KOJI、IGARASHI YOSHINORI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 4 Pages: 2183-2191
- DOI
  10.21873/anticanres.13333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08945
[Journal Article] Globo-A Binds to the Recombinant Natural Cytotoxicity Receptor NKp442018
- Author(s)
  Ito Kenichiro、Shiraishi Ryo、Higai Koji
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 9 Pages: 1480-1484
- DOI
  10.1248/bpb.b18-00312
- NAID
  130007480018
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-09-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08945
[Journal Article] Transcriptional Regulation of the Natural Cytotoxicity Receptor NKp44 Gene in Human NK cell Leukemia2018
- Author(s)
  Ito K, Kawana M, Iwata T, Higai K
- Journal Title
  
  Journal of Glycomics & Lipidomics
  
  Volume: 7(1) Pages: 1-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08945
[Journal Article] Quantitative measurements of sorafenib in patients with advanced hepatocellular carcinoma2018
- Author(s)
  Kobayashi K, Higai K, Matsuo K, Bannai Y, Horie H, Otakara Y, Li W, Koike K, Yanagino S,Watanabe K,Yoshio T,Wakui N, Nagai H
- Journal Title
  
  International Journal of Research Studies in Medical and Health Sciences
  
  Volume: 3(2) Pages: 14-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08945
[Journal Article] Sorafenib Decreases Dihydropyrimidine Dehydrogenase Gene Expression in Hepatocellular Carcinoma HepG2 Cells2018
- Author(s)
  Higai K, Otsuka N, Tanaka Y, Matsumoto K, Matsui M, Yanai K, Wakui N, Nagai H
- Journal Title
  
  Austin Journal of Pharmacology and Therapeutics
  
  Volume: 6(1)-1102 Pages: 1-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08945
[Journal Article] Glycan ligand specificity of killer lectin receptors2012
- Author(s)
  Higai K., Matsumoto K.
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 132(6) Pages: 705-12
- NAID
  130001888685
- URL
  https://www.jstage.jst.go.jp/article/yakushi/132/6/132_705/_article
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Unlike NKp30, natural cytotoxicity receptor NKp44 binds to multimeric alpha2,3-NeuNAc-containing N-glycans2012
- Author(s)
  Ito K., Higai K., Shinoda C., Sakurai M., Yanai K., Azuma Y., Matsumoto K.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 35 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Unlike NKp30, natural cytotoxicity receptor NKp44 binds to multimeric alpha2,3-NeuNAc-containing N-glycans2012
- Author(s)
  Ito K., Higai K., Shinoda C., Sakurai M., Yanai K., Azuma Y., Matsumoto K.
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 35 (4) Pages: 1-7
- URL
  https://www.jstage.jst.go.jp/article/bpb/35/4/35_4_594/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Glycan Ligand Specificity of Killer Lectin Receptors2012
- Author(s)
  K. Higai
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 132 Issue: 6 Pages: 705-712
- DOI
  10.1248/yakushi.132.705
- NAID
  130001888685
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2012-06-01
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] NKG2A and NKG2C bind to sulfated glycans and alpha2,3-NeuAc-containing glycoproteins2011
- Author(s)
  Xin X, Higai K., Imaizumi Y., Suzuki C.,Ito K., Itoh A., Matsumoto S., Azuma Y., Matsumoto K
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34 Pages: 480-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] NKG2A and NKG2C bind to sulfated glycans and alpha2,3-NeuAc-containing glycoproteins2011
- Author(s)
  Xin X, Higai K., Imaizumi Y., Suzuki C.,Ito K., Itoh A., Matsumoto S., Azuma Y.,and Matsumoto K.
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 34(4) Pages: 480-485
- URL
  https://www.jstage.jst.go.jp/article/bpb/34/4/34_4_480/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding of Natural cytotoxicity receptor NKp46 to sulfate- and alpha2,3-NeuAc-containing glycans and its mutagenesis2011
- Author(s)
  Ito K., Higai K., Sakurai M., Shinoda C., Yanai K., Azuma Y. and Matsumoto K.
- Journal Title
  
  Biochem, Biophys. Res. Commun
  
  Volume: 406 (3) Pages: 377-82
- URL
  http://www.sciencedirect.com/science/article/pii/S0006291X11002427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding properties of CD94 to sulfated glycans and akpha2,3-NeuAc-containing glycoprotein and its mutagenesis analysis2011
- Author(s)
  Higai K., Itoh A., Imaizumi Y., Suzuki C., Xin X., Azuma Y. Matsumoto K
- Journal Title
  
  The Open Biotechnology Journal
  
  Volume: 5 Pages: 14-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding properties of CD94 to sulfated glycans and alpha2,3-NeuAc-containing glycoprotein and its mutagenesis analysis2011
- Author(s)
  Higai K., Matsumoto S.,Kimura M.,Imaizumi Y.,Yanai K., Azuma Y., Matsumoto K.
- Journal Title
  
  The Open Biotechnology Journal
  
  Volume: 5 Pages: 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding properties of CD94 to sulfated glycans and a2,3-NeuAc-containing glycoproteins and mutagenesis analysis2011
- Author(s)
  Higai K, et al.
- Journal Title
  
  The Open Biotechnology Journal
  
  Volume: (inpress)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] Binding properties of CD94 to sulfated glycans and alpha2,3-NeuAc-containing glycoprotein and its mutagenesis analysis.2011
- Author(s)
  Higai K., Matsumoto S.,Kimura M.,Imaizumi Y.,Yanai K., Azuma Y., Matsumoto K.
- Journal Title
  
  The Open Biotechnology Journal
  
  Volume: 5 Pages: 33-38
- URL
  http://www.benthamscience.com/open/tobiotj/articles/V005/33TOBIOTJ.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding of Natural cytotoxicity receptor NKp46 to sulfate- and α2,3-NeuAc-containing glycans and its mutagenesis2011
- Author(s)
  Ito K., Higai K, et al.
- Journal Title
  
  Biochem, Biophys.Res.Commun
  
  Volume: 406(3) Pages: 377-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] Binding of Natural cytotoxicity receptor NKp46 to sulfate- and α2,3-NeuAc-containing glycans and its mutagenesis.2011
- Author(s)
  Ito K., Higai K., Sakurai M., Shinoda C., Yanai K., Azuma Y., Matsumoto K.
- Journal Title
  
  Biochem, Biophys.Res.Commun. 406(3)
  
  Pages: 377-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] NKG2A and NKG2C bind to sulfated glycans and α2,3-NeuAc- containing glycoproteins.2011
- Author(s)
  Xin X, Higai K., Imaizumi Y., Suzuki C, Ito K, Itoh A., Matsumoto S., Azuma Y, Matsumoto K
- Journal Title
  
  Biol.Pharm.Bull. 34(4)
  
  Pages: 480-485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] Binding of Natural cytotoxicity receptor NKp46 to sulfate- and alpha2,3-NeuAc-containing glycans and its mutagenesis2011
- Author(s)
  Ito K., Higai K., Sakurai M., Shinoda C., Yanai K., Azuma Y., Matsumoto K.
- Journal Title
  
  Biochem Biophys. Res. Commun.
  
  Volume: 406 Pages: 377-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding affinities of NKG2D and CD94 to sialyl Lewis X-expressing N-glycans and heparin2011
- Author(s)
  Higai K., Suzuki C., Imaizumi Y., Xin Xin, Azuma Y. and Matsumoto K
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 34(1) Pages: 8-12
- NAID
  130000402255
- URL
  https://www.jstage.jst.go.jp/article/bpb/34/1/34_1_8/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding affinities of NKG2D and CD94 to sialyl Lewis X-expressing N-glycans and heparin2011
- Author(s)
  Higai K., Suzuki C., Imaizumi Y., Xin Xin, Azuma Y.,Matsumoto K
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34 Pages: 8-12
- NAID
  130000402255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding properties of CD94 to sulfated glycans and alpha2,3-NeuAc-containing glycoprotein and its mutagenesis analysis2011
- Author(s)
  Higai K., Itoh A., Imaizumi Y., Suzuki C., Xin X., Azuma Y. and Matsumoto K.
- Journal Title
  
  The Open Biotechnology Journal
  
  Volume: 5 Pages: 14-20
- URL
  http://www.benthamscience.com/open/tobiotj/articles/V005/14TOBIOTJ.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790631
[Journal Article] Binding affinities of NKG2D and CD94 to sialyl Lewis X-expressing N-glycans and heparin.2010
- Author(s)
  Higai K., Suzuki C., Imaizumi Y., Xin Xin, Azuma Y., Matsumoto K
- Journal Title
  
  Biol.Pharm.Bull. 34(1)
  
  Pages: 8-12
- NAID
  130000402255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] Binding affinities of NKG2D and CD94 to sialyl Lewis X-expressing N-glycans and heparin2010
- Author(s)
  Higai K, et al.
- Journal Title
  
  Biol.Pharm.Bull.
  
  Volume: 34(1) Pages: 8-12
- NAID
  130000402255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] NKG2D and CD94 bind to heparin and sulfate-containing polysaccharides2009
- Author(s)
  K.Higai, et al.
- Journal Title
  
  Biochem,Biophys.Res.Commun 7174
  
  Pages: 709-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] NKG2D and CD94 bind to multimeric α2,3-linked N-acetylneu raminic acid.2009
- Author(s)
  Imaizumi Y., Higai K., Suzuki C, Azuma Y, Matsumoto K.
- Journal Title
  
  Biochem, Biophys.Res.Commun. 382
  
  Pages: 604-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] NKG2D and CD94 bind to heparin and sulfate-containing polysaccharides.2009
- Author(s)
  Higai K., Imaizumi Y., Suzuki C, Azuma Y., Matsumoto K.
- Journal Title
  
  Biochem, Biophys.Res.Commun. 386
  
  Pages: 709-714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Journal Article] NKG2D and CD94 bind to multimeric α2, 3-linked N-acetylneuraminic acid2008
- Author(s)
  Y. Imaizumi, K. Higai, et.al.
- Journal Title
  
  Biochem. Biophys. Res. Commun 328
  
  Pages: 604-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790398
[Journal Article] Transcriptional regulation of the fucosyltransferase VI gene in hepatocel lular carcinoma cells2008
- Author(s)
  Koji Higai, et. al.
- Journal Title
  
  Glycoconjugate Journal 3
  
  Pages: 225-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790398
[Journal Article] Binding properties of CD94 to sulfated glycans and α2,3-NeuAc-containing glycoprotein and its mutagenesis analysis.
- Author(s)
  Higai K., Itoh A., Imaizumi Y., Suzuki C., Xin X., Azuma Y., Matsumoto K.
- Journal Title
  
  The Open Biotechnology Journal. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] MICA/ADAM-9発現を誘導する免疫モジュレーターの探索2024
- Author(s)
  山本　桜、鈴木　樹、巽　康彰、桧貝　孝慈
- Organizer
  日本薬学会144年会
- Data Source
  KAKENHI-PROJECT-23K06288
[Presentation] 肝細胞がんにおけるアテゾリズマブ/ベバシズマブ併用療法に対するバイオマーカーの検討2024
- Author(s)
  山田　彩乃、京増　優佳、毛利　州秀、巽　康彰、和久井　紀貴、永井　英成、桧貝　孝慈
- Organizer
  日本薬学会144年会
- Data Source
  KAKENHI-PROJECT-23K06288
[Presentation] 肝細胞がんにおけるアテゾリズマブ/ベバシズマブ併用療法に対するバイオマーカーの検討2023
- Author(s)
  京増　優佳、毛利　州秀、巽　康彰、和久井　紀貴、永井　英成、桧貝　孝慈
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07141
[Presentation] 肝細胞癌患者血清中可溶性MICAおよびFGF-19濃度2022
- Author(s)
  諏訪原千絵歌、毛利州秀、桧貝孝慈、巽康彰、和久井紀貴、永井英成
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07141
[Presentation] NKG2D リガンドULBP1 の転写調節2022
- Author(s)
  小菅ほのか、桧貝孝慈、渡邉剛、小林康次郎、和久井紀貴、永井英成
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07141
[Presentation] Sorafenib による NKG2D リガンド ULBP1 発現2019
- Author(s)
  桧貝　孝慈、小林　康次郎、白石　凌、和久井　紀貴、永井　英成
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] Sorafenib による NKG2D リガンド ULBP1 発現への影響2018
- Author(s)
  小林　康次郎、白石　凌、桧貝　孝慈、和久井　紀貴、永井　英成
- Organizer
  第18回日本肝がん分子標的治療研究会
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 分子標的治療薬ソラフェニブによるマクロファージ活性化作用2017
- Author(s)
  石橋　由花、小林康次郎、桧貝　孝慈、向津　隆規、和久井　紀貴、松尾　和廣、永井　英成
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 分子標的治療薬ソラフェニブによるマクロファージ活性化作用2017
- Author(s)
  石橋　由花、小林康次郎、桧貝　孝慈、向津　隆規、和久井　紀貴、松尾　和廣、永井　英成
- Organizer
  第16回日本肝がん分子標的治療研究会
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 分子標的薬 Sorafenibの5-FU代謝に対する影響2017
- Author(s)
  小林康次郎、桧貝　孝慈、松尾　和廣、和久井　紀貴、永井　英成
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] Natural cytotoxicity receptors (NCRs) の糖鎖リガンドの特異性2017
- Author(s)
  白石凌、伊藤健一郎、桧貝孝慈
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 分子標的薬 Sorafenibの5-FU代謝に対する影響2017
- Author(s)
  小林康次郎、桧貝　孝慈、松尾　和廣、和久井　紀貴、永井　英成
- Organizer
  第16回日本肝がん分子標的治療研究会
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 分子標的治療薬ソラフェニブによるマクロファージ活性化作用2017
- Author(s)
  石橋　由花、小林康次郎、桧貝　孝慈、向津　隆規、和久井　紀貴、松尾　和廣、永井　英成
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] cMetを介したシグナル伝達の5-FUの細胞内動態に対する影響2017
- Author(s)
  小林康次郎、吉武　江奈、林佑樹、桧貝　孝慈、和久井　紀貴、永井　英成
- Organizer
  第15回日本肝がん分子標的治療研究会
- Place of Presentation
  イイノホール＆カンファレンスセンター（東京都千代田区）
- Year and Date
  2017-01-14
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 進行肝細胞癌合併肝硬変症例に対するソラフェニブ投与の肝星細胞の抑制効果2016
- Author(s)
  松井　太吾，永井　英成，向津　隆規，小林　康次郎，荻野　悠，松井　哲平，和久井紀貴，籾山　浩一，篠原　美絵，五十嵐　良典，住野　泰清，松尾　和廣，桧貝　孝慈
- Organizer
  第14回日本肝がん分子標的治療研究会
- Place of Presentation
  梅田スカイビル・スペース36（大阪府大阪市）
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] ソラフェニブのRaf/MEK/MAPK経路非依存的なHNF-4αに対する制御2016
- Author(s)
  川島　智実、坂内　良規、桧貝　孝慈、松尾　和廣、和久井　紀貴、永井　英成
- Organizer
  第14回日本肝がん分子標的治療研究会
- Place of Presentation
  梅田スカイビル・スペース36（大阪府大阪市）
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 進行肝細胞癌に対するソラフェニブと肝動注化学療法の有用性2016
- Author(s)
  永井　英成，松井　太吾，向津　隆規，小林　康次郎，荻野　悠，和久井　紀貴，籾山浩一，篠原　美絵，五十嵐　良典，住野　泰清，松尾　和廣，桧貝　孝慈
- Organizer
  第14回日本肝がん分子標的治療研究会
- Place of Presentation
  梅田スカイビル・スペース36（大阪府大阪市）
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 進行肝細胞癌合併肝硬変症例に対するソラフェニブ投与の肝線維化活性抑制効果2016
- Author(s)
  松井　太吾，永井　英成，向津　隆規，小林　康次郎，荻野　悠，松井　哲平，和久井紀貴，籾山　浩一，篠原　美絵，五十嵐　良典，住野　泰清，松尾　和廣，桧貝　孝慈
- Organizer
  第52回日本肝癌研究会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] NK細胞のIL-2刺激によるCD94-NKG2A発現様式の解析2016
- Author(s)
  五十部美穂、守屋恵梨、伊藤健一郎、桧貝孝慈
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-25460702
[Presentation] 進行肝細胞癌に対するソラフェニブと肝動注化学療法の有用性2016
- Author(s)
  永井　英成，松井　太吾，向津　隆規，小林　康次郎，荻野　悠，和久井　紀貴，籾山浩一，篠原　美絵，五十嵐　良典，住野　泰清，松尾　和廣，桧貝　孝慈
- Organizer
  第52回日本肝癌研究会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 分子標的治療薬ソラフェニブのKupffer細胞活性化の可能性2016
- Author(s)
  向津　隆規，永井　英成，松井　太吾，小林　康次郎，荻野　悠，松清　靖，松井　哲平，和久井　紀貴，籾山　浩一，五十嵐　良典，住野　泰清，松尾　和廣，桧貝　孝慈
- Organizer
  第20回日本肝臓学会大会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2016-11-04
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 分子標的治療薬ソラフェニブのKupffer細胞活性化の可能性2016
- Author(s)
  向津　隆規，永井　英成，松井　太吾，小林　康次郎，荻野　悠，松清　靖，松井　哲平，和久井　紀貴，籾山　浩一，五十嵐　良典，住野　泰清，松尾　和廣，桧貝　孝慈
- Organizer
  第52回日本肝癌研究会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京都港区）
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] SorafenibによるBCRP遺伝子調節機構の解析2016
- Author(s)
  藤井　翔子、桧貝　孝慈、松尾　和廣、和久井　紀貴、永井　英成
- Organizer
  第14回日本肝がん分子標的治療研究会
- Place of Presentation
  梅田スカイビル・スペース36（大阪府大阪市）
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] 分子標的治療薬ソラフェニブのKupffer細胞活性化の可能性2016
- Author(s)
  向津　隆規，永井　英成，松井　太吾，小林　康次郎，荻野　悠，松清　靖，松井　哲平，和久井　紀貴，籾山　浩一，五十嵐　良典，住野　泰清，松尾　和廣，桧貝　孝慈
- Organizer
  第14回日本肝がん分子標的治療研究会
- Place of Presentation
  梅田スカイビル・スペース36（大阪府大阪市）
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-16K08945
[Presentation] NK細胞における NCR2遺伝子の転写調節制御2014
- Author(s)
  川名　真代、伊藤健一郎,桧貝　孝慈、松本　宏治郎、多田　周右
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学（東京都町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-25460702
[Presentation] NK細胞における NCR2遺伝子の転写調節制御2014
- Author(s)
  伊藤健一郎, 川名　真代、桧貝　孝慈、東　祐太郎、松本　宏治郎、多田　周右
- Organizer
  第87回日本生化学学会大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-25460702
[Presentation] NCRsの糖鎖リガンドの解析2012
- Author(s)
  伊藤健一郎、篠田千尋、桧貝孝慈、松本宏治郎
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡マリンメッセ
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23790631
[Presentation] KillerLectin-likeReceptors(KLRs) の糖鎖リガンド特異性2012
- Author(s)
  今泉雄三、小松由佳、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第133回日本薬学会年会
- Place of Presentation
  パフィシコ横浜
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23790631
[Presentation] Naturalcytotoxicityreceptors(NCRs) の糖鎖リガンド特異性2012
- Author(s)
  伊藤健一郎、高橋真美子、桧貝孝慈、東祐太郎、吉田直弘、松本宏治郎
- Organizer
  第133回日本薬学会年会
- Place of Presentation
  パフィシコ横浜
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23790631
[Presentation] キラーレクチン様受容体の糖鎖リガンドの解析2011
- Author(s)
  桧貝孝慈、今泉雄三、Xin Xin 、松本早代、伊藤あゆみ、木村恵、柳内和幸、東祐太郎、松本宏治郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23790631
[Presentation] キラーレクチン様受容体の糖鎖リガンドの解析2011
- Author(s)
  桧貝　孝慈、今泉　雄三、Xin Xin 、松本　早代、伊藤　あゆみ、木村　恵、柳内　和幸、東　祐太郎、松本　宏治郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-23790631
[Presentation] NCR2およびNCR3の糖鎖リガンドの解析2011
- Author(s)
  篠田千尋、伊藤健一郎、桧貝孝慈
- Organizer
  第131回日本薬学会年会
- Place of Presentation
  (震災により、DVD・冊子による発表)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] Killer Lectin ReceptorおよびNatural Cytotoxicity Receptorの糖鎖リガンド特異性2011
- Author(s)
  桧貝孝慈、松本宏治郎
- Organizer
  第131回日本薬学会年会
- Place of Presentation
  (震災により、DVD・冊子による発表)
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NCR1の糖鎖リガンドの解析2011
- Author(s)
  松本宏治郎、櫻井瑞葉、伊藤健一郎、桧貝孝慈
- Organizer
  第131回日本薬学会年会
- Place of Presentation
  (震災により、DVD・冊子による発表)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] CRsの糖鎖リガンドの解析2011
- Author(s)
  篠田千尋、桧貝孝慈、伊藤健一郎、櫻井瑞葉、柳内和幸、東祐太郎、松本宏治郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23790631
[Presentation] NKG2DおよびCD94のsialyl Lewis X発現N型糖鎖およびヘパリンへの結合親和性2011
- Author(s)
  桧貝孝慈、鈴木千穂、今泉雄三、Xin Xin、東祐太郎、松本宏治郎
- Organizer
  第131回日本薬学会年会,震災により
- Place of Presentation
  DVD・冊子による発表
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] Killer Lectin ReceptorおよびNatural Cytotoxicity Receptorの糖鎖リガンド特異性2011
- Author(s)
  桧貝孝慈、松本宏治郎
- Organizer
  一般シンポジウム「糖鎖発現・機能の異常と疾患」第131回日本薬学会年会,震災により
- Place of Presentation
  DVD・冊子による発表
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NCR2およびNCR3の糖鎖リガンドの解析2011
- Author(s)
  篠田千尋、伊藤健一郎、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第131回日本薬学会年会,震災により
- Place of Presentation
  DVD・冊子による発表
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NCRsの糖鎖リガンドの解析2011
- Author(s)
  篠田　千尋、桧貝　孝慈、伊藤　健一郎、櫻井　瑞葉、柳内　和幸、東　祐太郎、松本　宏治郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-23790631
[Presentation] NCR1の糖鎖リガンドの解析2011
- Author(s)
  松本宏治郎、櫻井瑞葉、伊藤健一郎、桧貝孝慈、柳内和幸、東祐太郎
- Organizer
  第131回日本薬学会年会,震災により
- Place of Presentation
  DVD・冊子による発表
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2AおよびCの多分岐シアル酸およびヘパリンへの結合2011
- Author(s)
  Xin Xin、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第131回日本薬学会年会,震災により
- Place of Presentation
  DVD・冊子による発表
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2DおよびCD94のsialyl Lewis X発現N型糖鎖およびヘパリンへの結合親和性2011
- Author(s)
  桧貝孝慈
- Organizer
  第131回日本薬学会年会
- Place of Presentation
  (震災により、DVD・冊子による発表)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2AおよびCの多分岐シアル酸およびヘパリンへの結合2011
- Author(s)
  Xin Xin、桧貝孝慈
- Organizer
  第131回日本薬学会年会
- Place of Presentation
  (震災により、DVD・冊子による発表)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2D and CD94 bind to multimeric α2,3-linked N-acetylneuraminic acids2010
- Author(s)
  Imaizumi Y, Higai K
- Organizer
  The 25^<th> International Carbohydrate Symposium
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] CD94の多分岐シアル酸、GAGおよび硫酸化多糖類への結合2010
- Author(s)
  伊藤あゆみ、今泉雄三、桧貝孝慈
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2Dの多分岐シアル酸、GAGおよび硫酸化多糖類への結合2010
- Author(s)
  松本早代、木村恵、今泉雄三、桧貝孝慈
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NCR1の糖鎖リガンドの解析2010
- Author(s)
  櫻井瑞葉、伊藤健一郎、桧貝孝慈
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2AおよびCの多分岐シアル酸およびヘパリンへの結合2010
- Author(s)
  Xin Xin、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2D and CD94 bind to multimeric α2,3-linked N-acetylneu raminic acids2010
- Author(s)
  Imaizumi Y, Higai K, Suzuki C, Azuma Y, Matsumoto K
- Organizer
  The 25th International Carbohydrate Symposium
- Place of Presentation
  Makuhari, Japan
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] Natural cytotoxicity receptors のsialyl Lewis Xとの結合性2010
- Author(s)
  桧貝孝慈, 伊藤健一郎, 東祐太郎, 松本宏次郎
- Organizer
  第130回日本薬学会年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-31
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NCR2およびNCR3の糖鎖リガンドの解析2010
- Author(s)
  松本宏治郎、伊藤健一郎、篠田千尋、桧貝孝慈、東祐太郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2AおよびCの多分岐シアル酸およびヘパリンへの結合2010
- Author(s)
  Xin Xin、桧貝孝慈
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] CD94の多分岐シアル酸、GAGおよび硫酸化多糖類への結合2010
- Author(s)
  伊藤あゆみ、今泉雄三、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NCR2およびNCR3の糖鎖リガンドの解析2010
- Author(s)
  松本宏治郎、伊藤健一郎、篠田千尋、桧貝孝慈
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2D and CD94 bind to heparin and sulfate-containing polysaccharides2010
- Author(s)
  Higai K, Imaizumi Y, Suzuki C, Azuma Y, Matsumoto K
- Organizer
  The 25th International Carbohydrate Symposium
- Place of Presentation
  Makuhari, Japan
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2Dの多分岐シアル酸、GAGおよび硫酸化多糖類への結合2010
- Author(s)
  松本早代、木村恵、今泉雄三、桧貝孝慈、柳内和幸、東祐太郎、松本宏治郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2D and CD94 bind to heparin and sulfate-containing polysaccharides2010
- Author(s)
  Higai K
- Organizer
  The 25^<th> International Carbohydrate Symposium
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2010-08-03
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NCR1の糖鎖リガンドの解析2010
- Author(s)
  櫻井瑞葉、伊藤健一郎、桧貝孝慈、柳内和幸、東祐太郎、松本宏治郎
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2DおよびCD94の多分岐α2,3-シアル酸への結合2009
- Author(s)
  鈴木千穂、今泉雄三、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第29回日本糖質学会年会
- Place of Presentation
  飛騨
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] Glycan ligands of NKG2A and NKG2C.2009
- Author(s)
  Xin X, Suzuki C, Higai K, Azuma Y, Matsumoto K
- Organizer
  The 6th Seminar on Biomedical Sciences.
- Place of Presentation
  Tokyo.
- Year and Date
  2009-10-12
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2A and NKG2C bind to multimeric N-acetylneuraminic acid and heparin.2009
- Author(s)
  Xin Xin, 鈴木千穂、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2Dリガンドの解析2009
- Author(s)
  今泉雄三、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790398
[Presentation] NKG2Dリガンドの解析2009
- Author(s)
  Y. Imaizumi, K. Higai, et.al.
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2009-03-25
- Data Source
  KAKENHI-PROJECT-19790398
[Presentation] NKG2D and CD94 bind to heparin and sulfate-containing polysaccharides.2009
- Author(s)
  松本宏治郎、鈴木千穂、今泉雄三、桧貝孝慈、東祐太郎
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2D and CD94 bind to multimeric α2,3-linked N-acetylneu raminic acid.2009
- Author(s)
  桧貝孝慈、今泉雄三、鈴木千穂、東祐太郎、松本宏治郎
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790544
[Presentation] NKG2D mediates cytotoxicity against high sialyl Lewis X-expresing cells2008
- Author(s)
  Higai K., Imaizumi Y., Azuma Y, Matsumoto K
- Organizer
  Biochemistry and Molecular Biology
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-19790398
[Presentation] NKG2D糖鎖リガンドの解析2008
- Author(s)
  今泉雄三、楠原彬子、桧貝孝慈、東祐太郎、松本宏治郎
- Organizer
  第128回日本薬学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790398
[Presentation] NKG2D mediates cytotoxicity against high sialyl Lewis X-expresing cells2008
- Author(s)
  K. Higai, Y. Imaizumi, et.al.
- Organizer
  Biochemistry and Molecular Biology 2008
- Place of Presentation
  Kobe, Japan
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19790398
[Presentation] Transcriptional regulation of FUT VI in human hepatocellular carcinoma HepG2 cells2007
- Author(s)
  Higai K, Miyazaki N, Matsumoto K
- Organizer
  Biochemistry and Molecular biology 2007
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19790398
[Presentation] Transcriptional regulation of the fucosyltransferase VI gene in hepatocel lular carcinoma cells2007
- Author(s)
  Koji Higai, et. al.
- Organizer
  Biochemistry and Molecular Biology 2007
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19790398

1. 永井英成 (30349899)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results

HIGAI Koji 桧貝 孝慈

桧貝 孝慈 ヒガイ コウジ

Research Projects

Research Products

Co-Researchers

肝細胞がんに対する抗腫瘍免疫モジュレーターの開発と新規バイオマーカーの臨床応用Principal Investigator

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Development of remodeling medicine on hepatocellular carcinoma for inducible NK dependent cytotoxicity by molecular target medicinePrincipal Investigator

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Regulation of glycan-dependent cytotoxicity against advanced HCC by the molecular target drugPrincipal Investigator

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The Mechanism of Glycan-dependent Cytotoxicity by NK cellsPrincipal Investigator

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Regulation of NK cell activation by glycanPrincipal Investigator

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Glycan ligands of killer lectin-like receptors and regulation of NK functionsPrincipal Investigator

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biosynthesis regulation of sialyl lewis X in sera and its participation in immune responsePrincipal Investigator

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[Book] 「5.5組換え蛋白質:組換え蛋白質の発現と糖鎖修飾」「バイオマテリアルの基礎」分担2010

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[Book] 「5.5 組換え蛋白質:組換え蛋白質の発現と糖鎖修飾」「バイオマテリアルの基礎」分担2010

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[Book] 「組換え蛋白質:組換え蛋白質の発現と糖鎖修飾」バイオマテリアル-生体材料-特集「異分野融合のためのバイオマテリアルの基礎PART6」Vol.272009

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[Journal Article] Remaining Issues Related to Serum Cytokines in Patients with Unresectable Hepatocellular Carcinoma Treated by Atezolizumab plus Bevacizumab Combination Treatment2024

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[Journal Article] Importance of Atezolizumab Plus Bevacizumab Combination Treatment as First-line Therapy for Immunological Changes in Patients With Unresectable Hepatocellular Carcinoma2023

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[Journal Article] Lenvatinib Might Induce Activation of Host Immunity in Patients with Hepatocellular Carcinoma2022

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[Journal Article] Adaptation of lenvatinib treatment in patients with hepatocellular carcinoma and portal vein tumor thrombosis2021

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HIGAI Koji 桧貝孝慈

桧貝孝慈ヒガイコウジ