Yamamura Masahiro 山村真弘

… Alternative Names

山村真弘ヤマムラマサヒロ

YAMAMURA Masahiro 山村真弘

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Researcher Number	70299204
Other IDs
External Links
Affiliation (Current)	2025: 川崎医科大学, 医学部, 特任研究員
Affiliation (based on the past Project Information) *help	2015 – 2021: 川崎医科大学, 医学部, 講師 1999 – 2000: 川崎医科大学, 医学部, 助手
Review Section/Research Field	Except Principal Investigator Basic Section 50010:Tumor biology-related / Morphological basic dentistry / Digestive surgery / Digestive surgery
Keywords	Except Principal Investigator 膵癌 / 癌転移 / 走化性 / OPB-3206 / リンパ組織 / S100タンパク質 / 活性酸素 / リンパ向性転移 / マイクロアレイ / 細胞動態 … More / S100 protein / リンパ内皮細胞 / 扁平上皮癌 / 癌 / 病理学 / 癌関連遺伝子 / がん関連遺伝子 / 口腔扁平上皮癌 / 遺伝子機能解析 / DKK3 / 口腔癌 / 頭頸部扁平上皮癌 / 脂質 / 血清因子 / がん / 遊走 / 転移惹起因子 / Serum / Immunohistochemistry / Chemoprevention / Gelatin zymography / Matrix metalloproteinase (MMP) / Rapid production model for hamster pancreatic cancer / 血清学的早期診断 / 免疫染色 / tissue inhibitor of MMP(TIMP) / matrix metalloproteinase(MMP) / ハムスター / MMP / 血清 / 免疫組織化学的染色 / 発癌抑制 / ゼラチンザイモグラフィー / Matrix metalloproteinase(MMP) / 実験的膵管癌 Less

Why cancer cells metastasize to lymphatics from the early stage ?
- Principal Investigator
  
  Yamauchi Akira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kawasaki Medical School
Tumor control targeting specific cancer-associated gene, DKK3 in squamous cell carcinoma
- Principal Investigator
  
  KATASE Naoki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Explorative research of novel factors for pancreatic cancer metastasis and proliferation based on analysis of cell dynamics
- Principal Investigator
  
  Yamauchi Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kawasaki Medical School
Expression of matrix metalloproteinases (MMPs) during hamster pancreatic duct carcinogenesis, detection of serum MMPs in tumor-bearing hamster and chemopreventive effect of hamster pancreatic cancer
- Principal Investigator
  
  TSUNODA Tsukasa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KAWASAKI MEDICAL SCHOOL

All 2021 2020 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice2021
- Author(s)
  Sasaki Kyo、Nishina Sohji、Yamauchi Akira、Fukuda Kotaro、Hara Yuichi、Yamamura Masahiro、Egashira Kensuke、Hino Keisuke
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 11 Issue: 3 Pages: 739-762
- DOI
  10.1016/j.jcmgh.2020.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-19H03644, KAKENHI-PROJECT-18K07923, KAKENHI-PROJECT-21K07995
[Journal Article] DKK3 knockdown confers negative effects on malignant potency of head and neck squamous cell carcinoma cells via PI3K/Akt signal and MAPK pathways.2019
- Author(s)
  Katase N, Nishimatsu S, Yamauchi A, Yamamura M, Fujita S.
- Journal Title
  
  Int J Oncol.
  
  Volume: 54(3) Pages: 1021-1032
- DOI
  10.3892/ijo.2018.4667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11470
[Journal Article] Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts2019
- Author(s)
  Mitsui Yosuke、Tomonobu Nahoko、Watanabe Masami、Kinoshita Rie、Sumardika I Wayan、Youyi Chen、Murata Hitoshi et al.
- Journal Title
  
  Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
  
  Volume: 27 Issue: 8 Pages: 945-956
- DOI
  10.3727/096504019x15555408784978
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-19K16714, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
[Journal Article] Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device2017
- Author(s)
  Yamauchi A, Yamamura M, Katase N, Itadani M, Okada N, Kobiki K, Nakamura M, Yamaguchi Y, Kuribayashi F.
- Journal Title
  
  BMC CancerMar
  
  Volume: 31 Issue: 1 Pages: 234-244
- DOI
  10.1186/s12885-017-3218-4
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09671, KAKENHI-PROJECT-16K11470, KAKENHI-PROJECT-15K10201
[Journal Article] DKK3 Overexpression Increases Malignant Properties of Head and Neck Squamous Cell Carcinoma Cells.2017
- Author(s)
  Katase N, Nishimatsu SI, Yamauchi A, Yamamura M, Terada K, Itadani M, Okada N, Hassan NMM, Nagatsuka H, Ikeda T, Nohno T, Fujita S.
- Journal Title
  
  Oncology Research
  
  Volume: 26(1) Issue: 1 Pages: 45-58
- DOI
  10.3727/096504017x14926874596386
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11441, KAKENHI-PROJECT-16K11470, KAKENHI-PROJECT-15K10201
[Presentation] NOX4 on lymphatic endothelial cells (LEC) plays an important role on the migration of pancreatic cancer cells.2020
- Author(s)
  Akira Yamauchi, Masahiro Yamamura, Naoki Katase, Nahoko Tomonobu, Rie Kinoshita, Masakiyo Sakaguchi, and Shuichiro Okamoto
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] HSP90 inhibitor inhibit the activation of multiple kinase pathways and migration of pancreatic cancer cells2019
- Author(s)
  Yamamura M, Yamauchi A, Katase N, Yamaguchi　Y.
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07676
[Presentation] がん微小環境における酸化還元状態のリンパ行性転移への影響2017
- Author(s)
  山内明、山村真弘、片瀬直樹、栗林太
- Organizer
  第8回川崎医科大学学術集会
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Heat shock protein 90 inhibitors suppress PDGFRA reactivation and other receptor tyrosine kinase activation important in drug resistant gastrointestinal stromal tumors.2017
- Author(s)
  Yamamura M,Yamauchi A, Katase N, Okawaki M, Katata Y, Kuribayashi F, Kurebayashi J, Yamaguchi Y.
- Organizer
  American Association for Cancer Research Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] 口腔癌細胞株でのDKK3遺伝子ノックダウンは細胞の悪性度を低下させる2017
- Author(s)
  片瀬直樹、西松伸一郎、山内明、山村真弘、藤田修一、池田通
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-16K11470
[Presentation] 癌転移を惹起・増強する血清因子の探索2016
- Author(s)
  山内明, 山村真弘, 片瀬直樹, 山口佳之
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Gemcitabineは膵癌細胞の走化性に影響を与えないがDasatinibは走化性を抑制する2016
- Author(s)
  山内明, 山村真弘, 片瀬直樹, 板谷益美, 山口佳之, 栗林太
- Organizer
  第54回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-10-20
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] HSP90 inhibitor inhibit the activation of multiple kinase pathways and migration of pancreatic cancer cells.2016
- Author(s)
  Masahiro Yamamura, Akira Yamauchi, Naoki Katase, Yosuke Katata, Makoto Okawaki, Akira Sawaki, Tsutomu Nohno, Yoshiyuki Yamaguchi
- Organizer
  American Association for Cancer Research, Precision Medicine Series: TARGETING THE VULNERABILITIES OF CANCER
- Place of Presentation
  JW Marriott Marquis Miami (Miami, Florida, USA)
- Year and Date
  2016-05-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Functional analyses of DKK3 in oral squamous cell carcinoma cell lines2015
- Author(s)
  Naoki Katase, Masahiro Yamamura, Akira Yamauchi, Takahiro Suzuki, Kumiko Terada, Shin-ichiro Nishimatsu, Tsutomu Nohno
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] 口腔癌由来細胞におけるDKK3遺伝子発現の影響2015
- Author(s)
  片瀬直樹、寺田久美子、西松伸一郎、鈴木貴弘、松﨑秀紀、山村真弘、山内明、大槻剛巳、濃野勉
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] The new molecular target therapy of Hsp90 inhibition in esophageal squamous cell carcinoma2015
- Author(s)
  Masahiro Yamamura, Tsutomu Nohno, Akira Yamauchi, Naoki Katase, Makoto Okawaki, Akira Sawaki, Hideo Matsumoto, Toshihiro Hirai, Yoshiyuki Yamaguchi
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Pennsylvania Convention Center（Philadelphia, USA）
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] Suppressing pancreatic cancer metastasis by small molecular compunds2015
- Author(s)
  Yamauchi A, Yamamura M, Katase N, Itadani M, Okada N, Yamaguchi Y, Nohno T, Kuribayashi F
- Organizer
  International Conference of Cancer Immunotherapy and Macrophages 2015
- Place of Presentation
  University of Tokyo (Tokyo)
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10201
[Presentation] HSP90 inhibitor inhibit the activation of multiple kinase pathways of pancreatic cancer cells2015
- Author(s)
  Masahiro Yamamura, Akira Yamauchi, Naoki Katase,Toshihiro Hirai
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10201

1. Yamauchi Akira (80372431)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. KATASE Naoki (30566071)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. 栗林太 (60251443)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 阪口政清 (70379840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. TSUNODA Tsukasa (00110841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IKI Katsumichi (00268608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MAJIMA Toshimitsu (80209428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IWAMOTO Sueharu (60168599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Nakamura Masafumi (30372741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 西松伸一郎 (20222185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 岡本秀一郎 (10529035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. Itadaini Masumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 長塚仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 村田等

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamamura Masahiro 山村 真弘

山村 真弘 ヤマムラ マサヒロ

YAMAMURA Masahiro 山村 真弘

Research Projects

Research Products

Co-Researchers

Why cancer cells metastasize to lymphatics from the early stage ?

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tumor control targeting specific cancer-associated gene, DKK3 in squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Explorative research of novel factors for pancreatic cancer metastasis and proliferation based on analysis of cell dynamics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of matrix metalloproteinases (MMPs) during hamster pancreatic duct carcinogenesis, detection of serum MMPs in tumor-bearing hamster and chemopreventive effect of hamster pancreatic cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nanoparticle-Mediated Delivery of 2-Deoxy-D-Glucose Induces Antitumor Immunity and Cytotoxicity in Liver Tumors in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DKK3 knockdown confers negative effects on malignant potency of head and neck squamous cell carcinoma cells via PI3K/Akt signal and MAPK pathways.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DKK3 Overexpression Increases Malignant Properties of Head and Neck Squamous Cell Carcinoma Cells.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] NOX4 on lymphatic endothelial cells (LEC) plays an important role on the migration of pancreatic cancer cells.2020

Author(s)

Organizer

Data Source

[Presentation] HSP90 inhibitor inhibit the activation of multiple kinase pathways and migration of pancreatic cancer cells2019

Author(s)

Organizer

Data Source

[Presentation] がん微小環境における酸化還元状態のリンパ行性転移への影響2017

Author(s)

Organizer

Data Source

[Presentation] Heat shock protein 90 inhibitors suppress PDGFRA reactivation and other receptor tyrosine kinase activation important in drug resistant gastrointestinal stromal tumors.2017

Author(s)

Organizer

Data Source

[Presentation] 口腔癌細胞株でのDKK3遺伝子ノックダウンは細胞の悪性度を低下させる2017

Author(s)

Organizer

Data Source

[Presentation] 癌転移を惹起・増強する血清因子の探索2016

Author(s)

Organizer

Place of Presentation

Year and Date

Yamamura Masahiro 山村真弘

山村真弘ヤマムラマサヒロ

YAMAMURA Masahiro 山村真弘