MORITA Ayami 森田あや美 (近藤史実)

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… Alternative Names

森田あや美モリタアヤミ

近藤史実

近藤あや美

近藤史実

KONDO Ayami 近藤史実

森田あや美(近藤史美) モリタアヤミ（コンドウアヤミ）

近藤史美)

近藤史美コンドウアヤミ

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Researcher Number	70301629
External Links
Affiliation (Current)	2022: 愛知学院大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2016 – 2017: 愛知学院大学, 薬学部, 助教 2007 – 2009: Aichi Gakuin University, 薬学部, 助教 2006: 愛知学院大学, 薬学部, 助手 1998 – 2005: Aichi-Gakuin University, School of Dentistry Department of Pharamcology Research, 歯学部, 助手
Review Section/Research Field	Principal Investigator Functional basic dentistry Except Principal Investigator Functional basic dentistry / Functional basic dentistry / Conservative dentistry
Keywords	Principal Investigator lysophosphatidic acid / IL-6 / IL-8 / osteoblasts / RANKL / OPG / osteoblast / proliferation / vitamin K_2 / osteoprotegerin … More / mTOR / NF-κB / 骨芽細胞 / osteocalcin / vitamin K2 / IL-Iβ / Lysophosphatidic acid / interleukin-6 / interleukin-8 … More Except Principal Investigator 骨芽細胞 / RANKL / OPG / 破骨細胞 / アポトーシス / 交感神経 / CGRP / Apoptosis / サイトカイン / Osteoblast / apoptosis / イソプレナリン / cAMP / osteoblasts / cytokine / 破骨細胞形成 / β-受容体 / Osteoclastogenesis / Sympathetic neurons / 感覚神経 / ヒト骨芽細胞 / caspase / 分化 / 骨代謝 / 一酸化窒素 / ビオプテリン / mRNA / NF-χB / RT-PCR / Nitric Oxide / Biopterin / Cytokine / テトラヒドロビオプテリン / tetrahydrobiopterin / 軸索誘導因子 / 骨吸収 / VIP / エピネフリン / インターロイキン / ODF / ニューロトロフィン / セマフォリン / ネトリン / Osteoclast / Axon guidance molecules / p38MAPキナーゼ / Fas / Fasリガンド / オステオプロテグリン / ニューロペプチド / β-作動薬 / ATP / ブラジキニン / IL-6 / COX-II IL-6 / 頭頂骨 / ストレス / COX-II / Sensory neurons / Isoprenaline / neuropeptide / BMP-4 / 歯肉溝滲出液 / osteoprotegerin / 細胞周期 / 歯周病 / 顎関節症 / Caspase / BMP / osteoblast / BMP4 / ニューロペプチドY / 破骨細胞誘導 / 骨髄細胞 / Y1受容体 / ニューロペプチドY骨髄細胞 / アドレナリン / neuropeptide Y / isoprenaline / osteoclastogenesis / bone marrow cell / sympathetic nerve / bone metabolism / Y1 receptor / 神経 / 共培養 / カルシウムイオン / サソリ毒 / シナプス / 神経細胞 / 細胞内カルシウム / RAW264.7 / フォルスコリン / PKA / p-ERK / calphostin C / Nerve / Co-culture / Calcium ion / Scorpion venom / Synapse / 幹細胞 / 象牙芽細胞 / 脱細胞化 / 擬態マトリックス / 細胞分化 / ヒト幹細胞 Less

ヒト幹細胞と脱細胞化骨系組織特異的マトリックスを用いた再細胞化モデルの構築
- Principal Investigator
  
  茂木眞希雄
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Aichi Gakuin University
Basic research for protective therapy on bone-destructive diseasePrincipal Investigator
- Principal Investigator
  
  MORITA Ayami
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Physiological significance of RANKL on the pathogenetic mechanism in Periodontitis-related disease : Molecular Pharmacological Research
- Principal Investigator
  
  MOGI Makio
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Pharmacological study on bone metabolism by nervous activity
- Principal Investigator
  
  TOGARI Akifumi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
ROLE OF NEUROPEPTIDEY IN THE SYMPATHETIC NERVE REGULATION OF BONE METABOLISM
- Principal Investigator
  
  ARAI Michitsugu
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Molecular Parmacological Research for TNF-α receptor family on the pathogenetic mechanism in Periodontitis-related disease
- Principal Investigator
  
  MOGI Makio
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Pharmacological Study on Neuronal Regulation of Osteoclast Formation
- Principal Investigator
  
  TOGARI Akifumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi Gakuin University
Elucidation for inflammatory cytokines-induced apoptosis in osteoblastic cells
- Principal Investigator
  
  MOGI Makio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Departmeny of Pharmacology, School of Dentistry, Aichi-Gakuin University
Pharmacological Study on Neural Regulation of Bone Metabolism
- Principal Investigator
  
  TOGARI Akifumi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi-Gakuin University
Elucidation for anti-apoptotic action of tetrahydrobiopterin in osteoblastic cells
- Principal Investigator
  
  MOGI Makio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Department of Pharmacology, School of Dentistry, Aichi-Gakuin University
Pharmacological study on NO and biopterin synthesis in osteoblastic cells
- Principal Investigator
  
  TOGARI Akifumi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Aichi-Gakuin University

All 2016 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Wnt16 signaling is required for IL-1β-induced matrix metalloproteinase-13-regulated proliferation of human stem cell-derived osteoblastic cells.2016
- Author(s)
  Ozeki, N., Mogi, M., Hase, N., Hiyama, T., Yamaguchi, H., Kawai, R., Kondo, A., Nakata, K.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 17(2) Pages: 221-228
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11571
[Journal Article] Autophagy-related gene 5 and Wnt5 signaling pathway requires differentiation of embryonic stem into odontoblast-like cells.2016
- Author(s)
  Ozeki, N., Mogi, M., Hase, N., Hiyama, T., Yamaguchi, H., Kawai, R., Kondo, A., Matsumoto, T., Nakata, K.
- Journal Title
  
  Exp.Cell Res.
  
  Volume: 341(1) Pages: 92-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11571
[Journal Article] ELISA for RANKL -OPG complex in mouse sera.2010
- Author(s)
  Mogi, M., Kondo, A.
- Journal Title
  
  Journal of Im munoassay and Immunochemistry (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791377
[Journal Article] Down-regulation of NF-κB led to up-regulation of NGF production in mouse osteoblasts2010
- Author(s)
  Mogi, M., Kondo, A.
- Journal Title
  
  Journal of Immunoassay and Immunochemistry 31
  
  Pages: 92-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791377
[Journal Article] Down-regulation of NF-κB led to up-regulation of NGF producti on in mouse osteoblasts.2010
- Author(s)
  Mogi, M., Kondo, A.
- Journal Title
  
  Journal of Immunoa ssay and Immunochemistry 31
  
  Pages: 92-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791377
[Journal Article] Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells2009
- Author(s)
  Mogi, M., Kondo, A.
- Journal Title
  
  Biochemical Biophysical Research Communications 384
  
  Pages: 82-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791377
[Journal Article] Down-regulation of mTOR leads to up-regulation of osteoprotege rin in bone marrow cells.2009
- Author(s)
  Mogi, M., Kondo, A.
- Journal Title
  
  Biochemical Bioph ysical Research Communications 384
  
  Pages: 82-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791377
[Journal Article] Lysophosphatidic acid-stimulated interleukin-6 and-8 synthesis through LPA(1)receptors on human osteoblasts2008
- Author(s)
  Aki, Y., Kondo, A., Nakamura, H., Togari, A.
- Journal Title
  
  Archives of Oral Biology 53
  
  Pages: 207-213
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] Lysophosphatidic acid-stimulated interleukin-6 and -8 synthesis through LPA1 receptors on human osteoblasts.2008
- Author(s)
  Aki, Y., Kondo, A., et. al.
- Journal Title
  
  Archives of Oral Biology 53
  
  Pages: 207-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791377
[Journal Article] Lysophosphatidic acid-stimulated interleukin-6 and-8 synthesis through LPA(1) receptors on human osteoblasts.2008
- Author(s)
  Aki, Y., Kondo, A., Nakamura, H., Togari, A.
- Journal Title
  
  Archives of Oral Biology 53
  
  Pages: 207-213
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] Lysophosphatidic acid-stimulated interleukin-6 and-8 synthesis through LPA(1)receptors on human osteoblasts.2007
- Author(s)
  Aki, Y., Kondo, A., Nakamura, H., Togari, A.
- Journal Title
  
  Archives of Oral Biology 53
  
  Pages: 207-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] The role of the sympathetic nervous system in controlling bone metabolism2005
- Author(s)
  Togari, A., Arai, M., Kondo, A.
- Journal Title
  
  Expert Opinion on Therapeutic Targets 9(5)
  
  Pages: 931-940
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] The role of the sympathetic nervous system in controlling bone metabolism2005
- Author(s)
  Togari, A., Arai, M., Kondo, A.
- Journal Title
  
  Expert Opin Ther Targets 9(5)
  
  Pages: 931-940
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] The role of the sympathetic nervous system in controlling bone metabolism.2005
- Author(s)
  Togari, A., Arai, M., Kondo, A.
- Journal Title
  
  Expert Opin Ther Targets 9(5)
  
  Pages: 931-940
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Journal Article] Activation of osteoblastic functions by a mediator of pain, bradykinin.2004
- Author(s)
  Kondo A., Togari A.
- Journal Title
  
  Biochemical Pharmacology 68
  
  Pages: 1423-1431
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571782
[Journal Article] Activation of osteoblastic functions by a mediator of pain, bradykinin2004
- Author(s)
  Kondo, A., Togari, A.
- Journal Title
  
  Biochemical Pharmacology 68
  
  Pages: 1423-1431
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571782
[Journal Article] Activation of the peripheral sympathetic nervous system increased the expression of cyclooxygenase-2(COX-2) mRNA in mouse calvaria.2003
- Author(s)
  Inoue H., Kondo A., Togari A.
- Journal Title
  
  Neuroscience Letters 338
  
  Pages: 37-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571782
[Journal Article] In vivo stimulation of sympathetic nervous system modulates osteoblastic activity in mouse calvaria2003
- Author(s)
  Kondo, A., Togari, A.
- Journal Title
  
  American Journal of Physiology -Endocrinology and Metabolism 285
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571782
[Journal Article] In vivo stimulation of sympathetic nervous system modulates osteoblastic activity in mouse calvaria.2003
- Author(s)
  Kondo A., Togari A.
- Journal Title
  
  American Journal of Physiology- Endocrinology and Metabolism 285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571782
[Journal Article] Activation of the peripheral sympathetic nervous system increased the expression of cyclooxygenase-2(COX-2) mRNA in mouse calvaria2003
- Author(s)
  Inoue, H., Kondo, A., Togari, A.
- Journal Title
  
  Neuroscience Letters 338
  
  Pages: 37-40
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571782
[Presentation] ヒドロコルチゾンのヒト骨芽細胞増殖抑制における肝細胞増殖因子(HGF) の関与.2006
- Author(s)
  Tsunashima, Y., Kondo, A., Togari, A.
- Organizer
  The 48th Annual Meeting of Japanese Association for Oral Biology.
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] ヒドロコルチゾンのヒト骨芽細胞増殖抑制における肝細胞増殖閃子(HGF)の関与2006
- Author(s)
  綱島吉彦, 近藤史実, 戸苅彰史
- Organizer
  第48回歯科基礎医学会
- Place of Presentation
  横浜
- Year and Date
  2006-09-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Vitamin K2 inhibited IL-1β-increased proliferation of human osteoblasts2005
- Author(s)
  Morita, A., Matsuda, T., and Togari, A.
- Organizer
  2nd Joint Meeting of the European Calcified Tissue Society and the International Bone and Mineral Society
- Place of Presentation
  Geneva,Switzerland
- Year and Date
  2005-06-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] ヒト骨芽細胞における LPA 誘導性 IL-6 および IL-8 産生の作用機構.2005
- Author(s)
  Aki, Y., Morita, A., Nakamura, H., Togari, A.
- Organizer
  The 47th Annual Meeting of Japanese Association for Oral Biology.
- Place of Presentation
  Sendai
- Year and Date
  2005-09-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Signaling pathway of LPA-increased IL-6 and IL-8 synthesis in human osteoblasts.2005
- Author(s)
  Aki, Y., Morita, A., Togari, A., Nakamura, H.
- Organizer
  The 7th Joint-Scientific Meeting between JSCD & KACD
- Place of Presentation
  Tokyo
- Year and Date
  2005-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] IL-1β によるヒト骨芽細胞の増植促進における Vitamin K2 の抑制機序2005
- Author(s)
  Kondo, A., Togari, A.
- Organizer
  The 23rd Annual Meeting of the Japanese Society for Bone and Mineral Research.
- Place of Presentation
  Osaka
- Year and Date
  2005-07-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Sensory neuropeptide inhibits adrenergic stimulation of osteoclastogenesis in mouse bone marrow cells.2005
- Author(s)
  Togari, A., Hirukawa, K., Kondo, A., Arai, M., Ishizuka, K., Nakamura, H.
- Organizer
  2nd Joint Meeting of the European Calcified Tissue Society and the International Bone and Mineral Society(Geneva, Switzerland)
- Year and Date
  2005-06-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] ヒト骨芽細胞におけるLPA誘導性IL-6およびIL-8産生の作用機構2005
- Author(s)
  安藝義朗, 近藤史実, 中村洋, 戸苅彰史
- Organizer
  第47回歯科基礎医学会
- Place of Presentation
  仙台
- Year and Date
  2005-09-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] IL-1βによるヒト骨芽細胞の増殖促進におけるVitamin K2の抑制機序2005
- Author(s)
  近藤史実, 戸苅彰史
- Organizer
  第23回日木骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2005-07-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Vitamin K2 inhibited IL-1β-increased proliferation of human osteoblasts.2005
- Author(s)
  Morita, A., Matsuda, T., Togari, A.
- Organizer
  2nd Joint Meeting of the European Calcified Tissue Society and the International Bone and Mineral Society.
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2005-06-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] IL-1βによるヒト骨芽細胞の増殖促進に関する薬理学的解析2005
- Author(s)
  松田朋広, 近藤史実, 戸苅彰史
- Organizer
  第78回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2005-03-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] LPAのヒト骨芽細胞におけるIL-6およびIL-8産生に対する薬理学的研究2005
- Author(s)
  安藝義朗, 森田あや美, 戸苅彰史, 中村洋
- Organizer
  第123回日本歯科保存学会
- Place of Presentation
  東京
- Year and Date
  2005-11-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Sensory neuropeptide inhibits adrenergic stimulation of osteoclastogenesis in mouse bone marrow cells2005
- Author(s)
  Togari, A., Hirukawa, K., Kondo, A, Arai, M., Ishizuka, K., Nakamura, H.
- Organizer
  2nd Joint Meeting of the European Calcified Tissue Society and the International Bone and Mineral Society
- Place of Presentation
  Geneva,Switzerland
- Year and Date
  2005-06-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591956
[Presentation] Proliferative response of human osteoblastic cells to interleukin-1β.
- Author(s)
  Matsuda, T., Kondo, A., Togari, A.
- Organizer
  The 78th Annual Meeting of The Japanese Pharmacological Society.(Yokohama)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591956

1. MOGI Makio (00174334)

# of Collaborated Projects: 10 results

# of Collaborated Products: 2 results
2. TOGARI Akifumi (80126325)

# of Collaborated Projects: 8 results

# of Collaborated Products: 26 results
3. ARAI Michitsugu (20097538)

# of Collaborated Projects: 8 results

# of Collaborated Products: 5 results
4. HIRUKAWA Koji (60340147)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
5. OBATA Koji (40378229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 坪井孝博 (00308777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 尾関伸明 (70469005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MORITA Ayami 森田 あや美 (近藤 史実)

森田 あや美 モリタ アヤミ

近藤史実

近藤 あや美

近藤 史実

KONDO Ayami 近藤 史実

森田 あや美(近藤 史美) モリタ アヤミ（コンドウ アヤミ）

近藤 史美)

近藤 史美 コンドウ アヤミ

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Basic research for protective therapy on bone-destructive diseasePrincipal Investigator

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[Journal Article] Wnt16 signaling is required for IL-1β-induced matrix metalloproteinase-13-regulated proliferation of human stem cell-derived osteoblastic cells.2016

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[Journal Article] Autophagy-related gene 5 and Wnt5 signaling pathway requires differentiation of embryonic stem into odontoblast-like cells.2016

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[Journal Article] ELISA for RANKL -OPG complex in mouse sera.2010

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MORITA Ayami 森田あや美 (近藤史実)

森田あや美モリタアヤミ

近藤あや美

近藤史実

KONDO Ayami 近藤史実

森田あや美(近藤史美) モリタアヤミ（コンドウアヤミ）

近藤史美)

近藤史美コンドウアヤミ