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NAGASE Hisashi  長瀬 尚志

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… Alternative Names

長瀬 尚志  ナガセ ヒサシ

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Researcher Number 70303451
Other IDs
Affiliation (based on the past Project Information) *help 2012 – 2014: 信州大学, 医学部, 助教
2010 – 2011: 信州大学, 医学系研究科, 助教
2000: 信州大学, 医学部, 助手
1999: 信州大学, 医学部・寄生虫学, 助手
Review Section/Research Field
Principal Investigator
General medical chemistry / 寄生虫学(含医用動物学)
Except Principal Investigator
Laboratory animal science
Keywords
Principal Investigator
Th細胞 / γ-セクレターゼ / シグナル伝達 / Delta / Notch / IL-4 / 抗原提示細胞 / Th2 / IL-5 / 好酸球増多
Except Principal Investigator
インターロイキン / 疾患モデル動物 / 炎症
  • Research Projects

    (3 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (3 People)
  •  Generation of novel inflammatory disease model caused by dysregulation of IL-1 signaling

    • Principal Investigator
      KAKUTA Shigeru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  The contribution of Delta signaling regulated by γ-secretase on the differentiation of peripheral CD4 T cellsPrincipal Investigator

    • Principal Investigator
      NAGASE Hisashi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Shinshu University
  •  寄生蠕虫プロテアーゼのTh2分化における役割に関する研究Principal Investigator

    • Principal Investigator
      長瀬 尚志
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Shinshu University

All 2013 2012 2011

All Journal Article Book

  • [Book] Ohkawara T. γ-Secretase-Regulated Signaling and Alzheimer's Disease. Understanding Alzheimer's Disease2013

    • Author(s)
      Nakayama K, Nagase H, Koh CS
    • Publisher
      Croatia: InTech Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-22790278
  • [Book] Understanding Alzheimer's Disease2013

    • Author(s)
      Kohzo Nakayama, Hisashi Nagase, Chang-Sung Koh and Takeshi Ohkawara
    • Publisher
      InTech Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-22790278
  • [Book] Amyloids: Composition, Functions and Pathology2012

    • Author(s)
      Kohzo Nakayama, Hisashi Nagase, Chang-Sung Koh and Takeshi Ohkawara
    • Publisher
      NOVA Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-22790278
  • [Book] γ-Secretase-regulated signaling mechanisms: Notch and amyloid precursor protein. Neural Stem Cells & Therapy2012

    • Author(s)
      Nakayama K, Nagase H, Koh CS, Ohkawara T.
    • Publisher
      Sun T, editor. Croatia: InTech Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-22790278
  • [Book] Amyloid precursor protein: its signaling aspect and Alzheimer's disease. Amyloids, Halcheck IP2012

    • Author(s)
      Nakayama K, Nagase H, Koh CS, Ohkawara T
    • Publisher
      Vernon NR, editors. NY: Nova Science Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-22790278
  • [Book] Neural Stem Cells and Therapy2011

    • Author(s)
      Nakayama K, Nagase H, Koh CS, Ohkawara T
    • Total Pages
      28
    • Publisher
      InTech Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-22790278
  • [Journal Article] Notch, APP, and Alzheimer's Disease2012

    • Author(s)
      Nakayama K, Nagase H, Koh CS, Ohkawara T. γ-Secretase-Regulated Signaling
    • Journal Title

      Current Psychopharmacology.

      Volume: 1(2) Issue: 2 Pages: 155-166

    • DOI

      10.2174/2211556011201020155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790278, KAKENHI-PROJECT-23500442
  • [Journal Article] γ-Secretase-Regulated Signaling Pathways, such as Notch Signaling, Mediate the Differentiation of Hematopoietic Stem Cells, Development of the Immune System, and Peripheral Immune Responses2011

    • Author(s)
      Nagase H, Koh CS, Nakayama K
    • Journal Title

      Current Stem Cell Research & Therapy

      Volume: Vol.6 Pages: 131-141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790278
  • [Journal Article] γ-Secretase-Regulated Mechanisms Similar to Notch Signaling May Play a Role in Signaling Events, Including APP Signaling, Which Leads to Alzheimer's Disease2011

    • Author(s)
      Nakayama K, Nagase H, Koh CS, Ohkawara T.
    • Journal Title

      Cell Mol Neurobiol

      Volume: 31(6) Issue: 6 Pages: 887-900

    • DOI

      10.1007/s10571-011-9688-z

    • NAID

      120007110577

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790278, KAKENHI-PROJECT-23500442
  • [Journal Article] γ-Secretase-Regulated Signaling Pathways, such as Notch Signaling, Mediate the Differentiation of Hematopoietic Stem Cells, Development of the Immune System, and Peripheral Immune Responses2011

    • Author(s)
      Nagase H, Koh CS, Nakayama K
    • Journal Title

      Curr Stem Cell Res Ther

      Volume: 6(2) Issue: 2 Pages: 131-141

    • DOI

      10.2174/157488811795495459

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790278, KAKENHI-PROJECT-23500442
  • [Journal Article] The amyloid precursor protein intracellular domain alters gene expression and induces neuron-specific apoptosis2011

    • Author(s)
      Ohkawara T, Nagase H, Koh CS, Nakayama K
    • Journal Title

      Gene

      Volume: 475 Pages: 1-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790278
  • [Journal Article] The amyloid precursor protein intracellular domain alters gene expression and induces neuron-specific apoptosis.2011

    • Author(s)
      Ohkawara T, Nagase H, Koh CS, Nakayama K.
    • Journal Title

      Gene

      Volume: 475(1) Issue: 1 Pages: 1-9

    • DOI

      10.1016/j.gene.2010.11.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790278, KAKENHI-PROJECT-23500442
  • 1.  KAKUTA Shigeru (80345032)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  MATSUMOTO Kiyoshi (40173893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  MORI Masayuki (60273190)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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