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KIMURA Atsuomi  木村 敦臣

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Researcher Number 70303972
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 大阪大学, 大学院医学系研究科, 准教授
2014 – 2021: 大阪大学, 医学系研究科, 准教授
2013 – 2016: 大阪大学, 医学(系)研究科(研究院), 准教授
2012: 大阪大学, 大学院・医学系研究科, 准教授
2008 – 2012: Osaka University, 医学系研究科, 准教授 … More
2007: 阪大, 医学(系)研究科(研究院), 助教授
2006: 大阪大学, 大学院医学系研究科, 助教授
2003 – 2005: 大阪大学, 大学院・医学系研究科, 助教授
2003: 大阪大学, 医学系研究科, 助教授
2001 – 2002: 大阪大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biomedical engineering/Biological material science / Basic Section 90110:Biomedical engineering-related / Medium-sized Section 34:Inorganic/coordination chemistry, analytical chemistry, and related fields / Biomedical engineering/Biomaterial science and engineering / Radiation science / Radiation science
Except Principal Investigator
Biomedical engineering/Biomaterial science and engineering / Radiation science / Radiation science / Biological Sciences / Science and Engineering
Keywords
Principal Investigator
超偏極希ガス / 超偏極キセノン / MRI / 難治性肺疾患 / 新薬探索 / 前臨床評価 / 肺機能診断 / 慢性閉塞性肺疾患 / 生体磁気共鳴計測 / 肺機能 … More / MRS / 拡散 / 換気 / 脳機能 / 肺癌検出 / 超高感度 / 葉酸修飾酸化鉄ナノ粒子 / リポソーム / 酸化鉄ナノ粒子 / ナノメディスン / 肺癌検出システム / 磁性ナノ粒子 / 新生体素材開発 / 頑強化と持続可能化 / 熱可塑性ポリウレタン / hyper-CEST / stopped-flow / 新素材解析 / 熱可塑性ポリウレタ ン / Silk Fibroin / Cellulose Nanofiber / stopped-flow hyper-CEST / 高分子自由体積 / 超偏極キセノン生成装置の改良 / 超偏極キセノンNMR / 医用画像 / バイオイメージング / 肺がん / 肺疾患 / 肺癌 / MRI肺機能診断システム / ピルビン酸エチル / 完全偏極キセノン / 病態モデル / 超偏極 / 前臨床評価系 / イメージング / 肺MRI画像 / bSSFP法 / 偏極率 / 脳内緩和時間 / 灌流 / シネMRI画像 / 肺・脳機能連関 / 脳血流量 / 潅流 / 慢性閉塞性肺疾患(COPD) / 磁気共鳴イメージング(MRI) / 超偏極希ガス製造装置 / 連続フロー型 / 肺機能診断法 / 局所肺機能 / 核磁気共鳴 / 連続フロー … More
Except Principal Investigator
MRI / MRS / Xe NMR / 磁性ナノ粒子 / 磁気温熱療法 / 磁気粒子イメージング / 超偏極希ガス / 生体温度測定 / NMR / 磁気送達 / Lung Function / Brain Function / Mouse / Hyperpolarized Noble Gas / エマルジョン / 肺機能評価 / 肺画像 / 肺機能測定 / 脳機能測定 / マウス / pH / 水素イオン指数 / 核磁気共鳴 / 化学交換速度 / コンピュータシミュレーション / pH / 核磁気共鳴撮像法 / 化学交換飽和移動 / 磁場ゼロ線 / 薬剤送達システム / 医用画像 / ナノ」粒子メディスン / バイオイメージング / 磁性体ナノ粒子 / 動物実験 / 高感度 / 高分解能 / 画像再構成 / 磁場セロ線 / 細胞追跡法 / 温度感受性リポソーム / 磁気送達法 / ナノ粒子メディスン / 希釈ガス / 偏極率 / 磁気的相互作用 / 磁化移動 / エンタルピー / 平衡定数 / カリックスアレン / 包接相互作用 / Xe-129 / 二次元NMR / エマルジェン / 体内温度測定 / 多核種内部基準法 / 温度依存性 / Xe-129化学シフト / 超偏極希ガスNMR / 配向パラメーター / ジニコナゾール / ウニコナゾール / 直接結合定数 / 絶対構造決定 / 光学純度 / キラル液晶 / 光学異性体 Less
  • Research Projects

    (14 results)
  • Research Products

    (80 results)
  • Co-Researchers

    (16 People)
  •  Enhancement of robustness and sustainability of hyperpolarized xenon NMR and novel establishments as a fundamental technology for the development of new materialsPrincipal Investigator

    • Principal Investigator
      Kimura Atsuomi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 34:Inorganic/coordination chemistry, analytical chemistry, and related fields
    • Research Institution
      Osaka University
  •  ナノメディスンと超偏極希ガスMRIの融合による超高感度肺癌検出システムの開発Principal Investigator

    • Principal Investigator
      木村 敦臣
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Osaka University
  •  Development of a system for optimizing magnetic targeting and magnetic hyperthermia treatment using newly-developed magnetic particle imaging

    • Principal Investigator
      Murase Kenya
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Osaka University
  •  Development and application of an innovative pulmonary functional diagnostic system using hyperpolarized noble gas MRI aiming at complete polarizationPrincipal Investigator

    • Principal Investigator
      Kimura Atsuomi
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Osaka University
  •  Establishment of elemental techniques for magnetic particle imaging aiming at application to nanoparticle medicine

    • Principal Investigator
      Kenya Murase
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Osaka University
  •  Development of a new method for quantifying chemical exchange rate and visualizing pH using CEST MRI

    • Principal Investigator
      MURASE Kenya
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Osaka University
  •  Development of preclinical system based on pulmonary functional imaging by hyperpolarized Xe MRIPrincipal Investigator

    • Principal Investigator
      Kimura Atsuomi
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Osaka University
  •  Development andApplication of Methodology of Magnetic Resonance Measurement of Hyperpolarized Noble Gas Contributable to Physiological Diagnosis.Principal Investigator

    • Principal Investigator
      KIMURA Atsuomi
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Osaka University
  •  超偏極希ガスのMRI/MRSによる新規肺機能診断法の開発に関する研究Principal Investigator

    • Principal Investigator
      木村 敦臣
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Radiation science
    • Research Institution
      Osaka University
  •  簡易連続型超偏極希ガス生成装置の試作と水素や炭素核の高感度MRI実験への応用

    • Principal Investigator
      藤原 英明
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Osaka University
  •  超偏極希ガスの連続フロー型製造装置開発と脳機能磁気共鳴研究への応用Principal Investigator

    • Principal Investigator
      木村 敦臣
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Osaka University
  •  Applied Clinical Study on Hyperpolarized Noble Gas MRI/MRS using Pathologic Model Animal

    • Principal Investigator
      FUJIWARA Hideaki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Osaka University
  •  液晶NMR法におけるキラル液晶系の利用と天然分子の絶対構造決定の開発

    • Principal Investigator
      FUJIWARA Hideaki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Osaka University
  •  超偏極希ガス簡易供給装置の開発と高感度磁気共鳴による脳機能計測の研究

    • Principal Investigator
      藤原 英明
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] Hyperpolarized and Inert Gas MRI in Research and Medicine2017

    • Author(s)
      Imai H, Kimura A, Fujiwara H.
    • Total Pages
      15
    • Publisher
      Elsevier
    • ISBN
      9780128036754
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Book] Hyperpolarized Xenon-129 Magnetic Resonance2015

    • Author(s)
      Kimura A, Imai H, Fujiwara H
    • Total Pages
      483
    • Publisher
      Cambridge: Royal Society of Chemistry
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Book] Hyperpolarized Xenon-129 Magnetic Resonance.2015

    • Author(s)
      Kimura A, Imai H, Fujiwara H.
    • Total Pages
      16
    • Publisher
      Royal Society of Chemistr
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Book] Hyperpolarized Xenon-129 Magnetic Resonance2015

    • Author(s)
      Kimura A, Imai H, Fujiwara H
    • Total Pages
      483
    • Publisher
      Cambridge: Royal Society of Chemistry
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004

    • Author(s)
      T.Wakayama, T.Oose, M.Narazaki, A.Kimura, H.Fujiwara
    • Total Pages
      4
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004

    • Author(s)
      H.Fujiwara, A.Kimura, T.Wakayama
    • Total Pages
      8
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Book] Quantitation in Biomedical Imaging with RET and MRI, ICS1265.2004

    • Author(s)
      M.Narazaki, T.Wakayama, A.Kimura, H.Fujiwara
    • Total Pages
      4
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-14657215
  • [Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004

    • Author(s)
      Y.Kawata, T.Kamiya, H.Miura, A.Kimura, H.Fujiwara
    • Total Pages
      4
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-14657215
  • [Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004

    • Author(s)
      T.Wakayama, T.Oose, M.Narazaki, A.Kimura, H.Fujiwara
    • Total Pages
      4
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-14657215
  • [Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004

    • Author(s)
      M.Narazaki, T.Wakayama, A.Kimura, H.Fujiwara
    • Total Pages
      4
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004

    • Author(s)
      H.Fujiwara, A.Kimura, T.Wakayama
    • Total Pages
      8
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-14657215
  • [Book] Quantitation in Biomedical Imaging with PET and MRI, ICS1265.2004

    • Author(s)
      Y.Kawata, T.Kamiya, H.Miura, A.Kimura, H.Fujiwara
    • Total Pages
      4
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] Targeted Imaging of Lung Cancer with Hyperpolarized 129Xe MRI Using Surface-Modified Iron Oxide Nanoparticles as Molecular Contrast Agents.2022

    • Author(s)
      Kimura A, Utsumi S, Shimokawa A, Nishimori R, Hosoi R, Stewart NJ, Imai H, Fujiwara H.
    • Journal Title

      Cancers (Basel).

      Volume: 14 Pages: 6070-6070

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K20411
  • [Journal Article] Quantitative assessment of regional lung ventilation in emphysematous mice using hyperpolarized 129Xe MRI with a continuous flow hyperpolarizing system.2022

    • Author(s)
      Wakayama T, Ueyama T, Imai F, Kimura A, Fujiwara H.
    • Journal Title

      Magn Reson Imaging.

      Volume: 92 Pages: 88-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K20411
  • [Journal Article] Inflammation during Lung Cancer Progression and Ethyl Pyruvate Treatment Observed by Pulmonary Functional Hyperpolarized 129Xe MRI in Mice2021

    • Author(s)
      Kimura Atsuomi、Utsumi Seiya、Shimokawa Akihiro、Nishimori Renya、Stewart Neil J.、Kamada Yoshihiro、Imai Hirohiko、Fujiwara Hideaki
    • Journal Title

      Contrast Media & Molecular Imaging

      Volume: 2021 Pages: 1-10

    • DOI

      10.1155/2021/9918702

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08383, KAKENHI-PROJECT-23K20411
  • [Journal Article] Analysis of NMR Adsorption Isotherms of Zeolite ZSM-5: Adsorption Profiles Derived from the Pressure and Temperature Dependences of <sup>129</sup>Xe NMR Chemical Shift and Signal Intensity2021

    • Author(s)
      FUJIWARA Hideaki、IMAI Hirohiko、ADACHI Yuko、KIMURA Atsuomi
    • Journal Title

      Anal. Sci.

      Volume: 37 Issue: 12 Pages: 1803-1810

    • DOI

      10.2116/analsci.21P202

    • NAID

      130008127597

    • ISSN
      0910-6340, 1348-2246
    • Year and Date
      2021-12-10
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K18980
  • [Journal Article] Multiplexed 129Xe HyperCEST MRI Detection of Genetically Reconstituted Bacterial Protein Nanoparticles in Human Cancer Cells2020

    • Author(s)
      Mizushima Ryota、Inoue Kanako、Fujiwara Hideaki、Iwane Atsuko H.、Watanabe Tomonobu M.、Kimura Atsuomi
    • Journal Title

      Contrast Media & Molecular Imaging

      Volume: 2020 Pages: 1-10

    • DOI

      10.1155/2020/5425934

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05409, KAKENHI-PROJECT-23K20411
  • [Journal Article] Stability Enhancement of <sup>129</sup>Xe Hyperpolarizing System Using Alkali Metal Vapor in Spin-Exchange Optical Pumping Cell to Achieve High NMR Sensitivity2019

    • Author(s)
      Fujiwara H, Imai H, Kimura A.
    • Journal Title

      Anal. Sci.

      Volume: 35 Issue: 8 Pages: 869-873

    • DOI

      10.2116/analsci.19P047

    • NAID

      130007689343

    • ISSN
      0910-6340, 1348-2246
    • Year and Date
      2019-08-10
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Journal Article] Adipose Tissue-Derived Stem Cells Have the Ability to Differentiate into Alveolar Epithelial Cells and Ameliorate Lung Injury Caused by Elastase-Induced Emphysema in Mice.2019

    • Author(s)
      Fukui E, Funaki S, Kimura K, Momozane T, Kimura A, Chijimatsu R, Kanzaki R, Kanou T, Ose N, Minami M, Miyagawa S, Sawa Y, Okumura M, Shintani Y.
    • Journal Title

      Stem Cells Int.

      Volume: 2019 Pages: 5179172-5179172

    • DOI

      10.1155/2019/5179172

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H03006, KAKENHI-PROJECT-18J01264, KAKENHI-PROJECT-18K16417
  • [Journal Article] Ethyl Pyruvate Improves Pulmonary Function in Mice with Bleomycin-induced Lung Injury as Monitored with Hyperpolarized 129Xe MR Imaging.2018

    • Author(s)
      Hodono S, Shimokawa A, Stewart NJ, Yamauchi Y, Nishimori R, Yamane M, Imai H, Fujiwara H, Kimura A.
    • Journal Title

      Magn Reson Med Sci.

      Volume: 17 Pages: 331-337

    • NAID

      130007496955

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Journal Article] Continuous flow production of concentrated hyperpolarized xenon gas from a dilute xenon gas mixture by buffer gas condensation.2017

    • Author(s)
      Imai H, Yoshimura H, Kimura A, Fujiwara H.
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 7352-7352

    • DOI

      10.1038/s41598-017-07695-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H03006, KAKENHI-PROJECT-15K01283
  • [Journal Article] Treatment response of ethyl pyruvate in a mouse model of chronic obstructive pulmonary disease studied by hyperpolarized 129Xe MRI.2017

    • Author(s)
      Kimura A, Yamauchi Y, Hodono S, Stewart NJ, Hosokawa O, Hagiwara Y, Imai H, Fujiwara H.
    • Journal Title

      Magn Reson Med

      Volume: 78 Pages: 721-729

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Journal Article] Treatment response of ethyl pyruvate in a mouse model of chronic obstructive pulmonary disease studied by hyperpolarized 129Xe MRI.2016

    • Author(s)
      Kimura A, Yamauchi Y, Hodono S, Stewart NJ, Hosokawa O, Hagiwara Y, Imai H, Fujiwara H.
    • Journal Title

      Magn Reson Med

      Volume: 印刷中 Issue: 2 Pages: 721-729

    • DOI

      10.1002/mrm.26458

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03006, KAKENHI-PROJECT-15K01283
  • [Journal Article] Hyperpolarized 129Xe MRI Using Isobutene as a New Quenching Gas2016

    • Author(s)
      Hodono S, Imai H, Yamauchi Y, Kawamura A, Matsumoto H, Okumura S, Fujiwara H, Kimura A.
    • Journal Title

      NMR Biomed

      Volume: 29 Issue: 10 Pages: 1414-1419

    • DOI

      10.1002/nbm.3585

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H03006, KAKENHI-PROJECT-15K01283
  • [Journal Article] Regional fractional ventilation mapping in spontaneously breathing mice using hyperpolarized 129Xe MRI.2015

    • Author(s)
      Imai H, Matsumoto H, Miyakoshi E, Okumura S, Fujiwara H, Kimura A.
    • Journal Title

      NMR Biomed

      Volume: 28 Pages: 24-29

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Journal Article] Regional fractional ventilation mapping in spontaneously breathing mice using hyperpolarized 129Xe MRI.2015

    • Author(s)
      Imai H, Matsumoto H, Miyakoshi E, Okumura S, Fujiwara H, Kimura A.
    • Journal Title

      NMR Biomed

      Volume: 28 Pages: 24-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Journal Article] Small animal imaging with hyperpolarized 129Xe magnetic resonance.2014

    • Author(s)
      Imai H, Kimura A, Fujiwara H.
    • Journal Title

      Anal Sci

      Volume: 30 Pages: 157-166

    • NAID

      130004442237

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Journal Article] Direct Imaging of Alveolar Gas Uptake with Hyperpolarized 129xe Ultra-short Echo-Time MRI and Its Application to Physiological Assessment of Emphysema in Mouse Lung.2013

    • Author(s)
      井口智史、木村敦臣
    • Journal Title

      Magn. Reson. Med.

      Volume: in press Issue: 1 Pages: 592-600

    • DOI

      10.1002/mrm.24452

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408, KAKENHI-PROJECT-23700534, KAKENHI-PROJECT-24300163
  • [Journal Article] Validation of non-invasive morphological and diffusion imaging in mouse emphysema by micro-CT and hyperpolarized ^129Xe MRI2013

    • Author(s)
      Satoshi Tetsumoto, Yoshioto Takeda, Hirohiko Imai, et al.
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 掲載決定 Issue: 4 Pages: 592-600

    • DOI

      10.1165/rcmb.2012-0350oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700534, KAKENHI-PROJECT-24300163, KAKENHI-PROJECT-25461386
  • [Journal Article] Direct Imaging of Alveolar Gas Uptake with Hyperpolarized ^<129>xe Ultra-short Echo-Time MR1 and Its Application to Physiological Assessment of Emphysema in Mouse Lung.2013

    • Author(s)
      井口智史、木村敦臣
    • Journal Title

      Magn. Reson. Med.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Journal Article] Development of a fast method for quantitative measurement of hyperpolarized ^129Xe dynamics in mouse brain2012

    • Author(s)
      Hirohiko Imai, et al.
    • Journal Title

      NMR Biomed

      Volume: 25巻 Issue: 2 Pages: 210-217

    • DOI

      10.1002/nbm.1733

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700534, KAKENHI-PROJECT-24300163
  • [Journal Article] Development of a Fast Method for Quantitative Measurement of Hyperpolarized ^129Xe Dynamics in Mouse Brain.2012

    • Author(s)
      Imai H, Kimura A, Akiyama K, Ota C, Okimoto K, Fujiwara H.
    • Journal Title

      NMR Biomed

      Volume: 25 Pages: 210-217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Development of a Fast Method for Quantitative Measurement of Hyperpolarized 129xe Dynamics in Mouse Brain.2012

    • Author(s)
      今井宏彦、木村敦臣
    • Journal Title

      NMR Biomed

      Volume: 25 Pages: 210-217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Hyperpolarized ^129Xe Lung MRI in Spontaneous Breathing Mice with Respiratory Gated Fast Imaging and Its Application to Pulmonary Functional Imaging.2011

    • Author(s)
      Imai H, Kimura A, Hori Y, Iguchi S, Kitao T, Okubo E, Ito T, Matsuzaki T, Fujiwara H.
    • Journal Title

      NMR Biomed

      Volume: 24 Pages: 1-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Hyperpolarized ^129Xe MR Imaging with Balanced Steady-State Free Precession in Spontaneously Breathing Mouse Lungs.2011

    • Author(s)
      Imai F, Kashiwagi R, Imai H, Iguchi S, Kimura A, Fujiwara H.
    • Journal Title

      Magn Reson Med Sci

      Volume: 10 Pages: 33-40

    • NAID

      10029698048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Confirming the Origin of Dissolved-Phase Hyperpolarized ^129Xe Signal from the Mice Chest Based on Experimental Evidence from Extensive Magnetic Resonance Measurements.2011

    • Author(s)
      Narazaki M, Kimura A, Imai H, Fujiwara H.
    • Journal Title

      Magn Reson Med Sci

      Volume: 10 Pages: 149-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Comprehensive Pulmonary Evaluation of Emphysematous Mice Using Hyperpolarized ^<129>Xe MRI/MRS Under Spontaneous Breathing Mode2010

    • Author(s)
      今井宏彦、木村敦臣
    • Journal Title

      Proc.Intl.Soc.Mag.Reson.Med.

      Volume: 18 Pages: 4608-4608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Hyperpolarized ^129Xe dynamic study in mouse lung under spontaneous respiration: Application to murine tumor B16BL6 melanoma.2010

    • Author(s)
      Imai H, Kimura A, Ito T, Fujiwara H.
    • Journal Title

      Eur J Radiol

      Volume: 73 Pages: 196-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Hyperpolarized ^<129>Xe dynamic studay in mouse lung under spontaneous respiration : Application to murine tumor B16BL6 melanoma2010

    • Author(s)
      今井宏彦、木村敦臣
    • Journal Title

      Eur J Radiol

      Volume: 73 Pages: 196-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Non-invasive Detection of Pulmonary Tissue Destruction in a Mouse Model of Emphysema Using Hyperpolarized ^129Xe MRS under Spontaneous Respiration.2010

    • Author(s)
      Imai H, Kimura A, Iguchi S, Hori Y, Masuda S, Fujiwara H.
    • Journal Title

      Magn Reson Med

      Volume: 64 Pages: 929-938

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Non-invasive Detection of Pulmonary Tissue Destruction in a Mouse Model of Emphysema Using Hyperpolarized ^<129>Xe MRS under Spontaneous2010

    • Author(s)
      今井宏彦、木村敦臣
    • Journal Title

      Magn Reson Med

      Volume: 64 Pages: 929-938

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Journal Article] Improvement of T_1 Determination of Hyperpolarized ^<129>Xe in Mouse Brain under Controlled-Flow2005

    • Author(s)
      木村 敦臣
    • Journal Title

      Magnetic Resonance in Medical Sciences (印刷中)

    • NAID

      10014455584

    • Data Source
      KAKENHI-PROJECT-14770453
  • [Journal Article] Practical Application of NMR Spectra of ^<129>Xe dissolved in Red Blood Cell2004

    • Author(s)
      Y.Kawata, T.Kamiya, H.Miura, A.Kimura, H.Fujiwara
    • Journal Title

      International Congress Series 1265

      Pages: 172-176

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] MRI and MRS of Mouse Head at 9.4T using Hyperpolarized Xenon Gas2004

    • Author(s)
      T.Wakayama, T.Oose, M.Narazaki, A.Kimura, H.Fujiwara
    • Journal Title

      International Congress Series 1265

      Pages: 167-171

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] Improvement of T1 Determination of Hyperpolarized 129Xe in Mouse Brain under Controlled-2004

    • Author(s)
      A.Kimura, T.Wakayama, M.Narazaki, Y.Kawata, T.Ueyama, H.Fujiwara
    • Journal Title

      International Congress Series 1265

      Pages: 199-205

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] MRS of Hypperpolarized ^<129>Xe in the Chest of Mouse - Effect of Contrast Agents on the MRS2004

    • Author(s)
      M.Narazaki, T.Wakayama, A.Kimura, H.Fujiwara
    • Journal Title

      International Congress Series 1265

      Pages: 177-180

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] Hyperpolarized ^<129>Xe as a Novel Probe Agent of Lung Functions in MRI and MRS. Experimental Results with Mice at 9.4T2004

    • Author(s)
      H.Fujiwara, A.Kimura, T.Wakayama
    • Journal Title

      International Congress Series 1265

      Pages: 124-130

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] Improvement of T_1 Determination of Hyperpolarized ^<129>Xe in Mouse Brain under Controlled-Flow2004

    • Author(s)
      A.Kimura
    • Journal Title

      Magn.Reson.Med.Sci 3

      Pages: 199-205

    • NAID

      10014455584

    • Data Source
      KAKENHI-PROJECT-17689037
  • [Journal Article] MRS of Hyperpolarized ^<129>Xe in the Chest of Mouse -Effect of Contrast Agents on the MRS2004

    • Author(s)
      M.Narazaki, T.Wakayama, A.Kimura, H.Fujiwara
    • Journal Title

      International Congress Series 1265

      Pages: 177-180

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] ^<19>F Magnetic Resonance Imaging of Perfluorooctanoic Acid Encapsulated in Liposome for Biodistribution Measurement2004

    • Author(s)
      A.Kimura, M.Narazaki, Y.Kanazawa, H.Fujiwara
    • Journal Title

      Mag.Reson.Imag. 22

      Pages: 855-860

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] Improvement of T1 Determination of Hyperpolarized 129Xe in Mouse Brain under Controlled- Flow2004

    • Author(s)
      A.Kimura, T.Wakayama, M.Narazaki, Y.Kawata, T.Ueyama, H.Fujiwara
    • Journal Title

      International Congress Series 1265

      Pages: 199-205

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] Analysis of the Effect of Foreign Gases in the Production of Hyperpolarized 129Xe Gas on a Simple System working under Atmospheric Pressure2003

    • Author(s)
      J.Fukutomi, E.Suzuki, T.Shimizu, A.Kimura, H.Fujiwara
    • Journal Title

      J.magn.Reson. 160

      Pages: 26-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Journal Article] Analysis of the Effect of Foreign Gases in the Production of Hyperpolarized 129Xe Gas on a Simple System working under Atmospheric Pressure2003

    • Author(s)
      J.Fukutani, E.Suzuki, T.Shimizu, A.Kimura, H.Fujiwara
    • Journal Title

      J.magn.Reson. 160

      Pages: 26-32

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370277
  • [Presentation] 表面修飾酸化鉄ナノ粒子を 分子造影剤として使用した超偏極129XeMRIによる 肺癌イメージング2023

    • Author(s)
      下出 剛史、三木 琴音、内海 誠也、木村 敦臣
    • Organizer
      第51回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-23K20411
  • [Presentation] 循環型超偏極キセノンガス生成供給装置を利用したナノ細孔解析.セルロースナノ    ファイバーについて2023

    • Author(s)
      藤原英明,今井宏彦,木村敦臣
    • Organizer
      第62回NMR討論会
    • Data Source
      KAKENHI-PROJECT-21K18980
  • [Presentation] 腫瘍特異的造影剤を用いた超偏極129Xe MRIにおける肺腫瘍イメージングの基礎的検討2022

    • Author(s)
      木村敦臣 , 内海誠也 , 宮岡美咲 , 森明亮我 , 今井宏彦
    • Organizer
      第50回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-23K20411
  • [Presentation] 造影剤を用いた超偏極 129Xe MRIにおける肺癌イメージングの基礎的検討2021

    • Author(s)
      木村敦臣, 内海誠也, 宮岡美咲, 森明亮我, 谷村成起, 今井宏彦
    • Organizer
      日本磁気共鳴医学会
    • Data Source
      KAKENHI-PROJECT-23K20411
  • [Presentation] Xe-NMR Study of Zeolites. How to enhance the Reliability Adsorption Properties determined by NMR experiments2021

    • Author(s)
      Hideaki Fujiwara, Hirohiko Imai, Yuko Adachi, Atsuomi Kimura
    • Organizer
      22nd International Society of Magnetic Resonance Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K18980
  • [Presentation] 超偏極129Xe MRIによるピルビン酸エチルの早期肺癌治療効果の観察2020

    • Author(s)
      内海誠也, 西森廉弥, 吉田月帆, 森勇斗, 木村敦臣
    • Organizer
      日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-23K20411
  • [Presentation] 超偏極129Xeを用いた肺がんモデルマウスに対するピルビン酸エチルの薬効評価2019

    • Author(s)
      内海誠也, 吉岡佐希子, 西森廉弥, 木村敦臣
    • Organizer
      第47回日本磁気共鳴医学会大会
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Presentation] 超偏極キセノンガス生成供給装置普及版の作成と応用2018

    • Author(s)
      藤原英明, 今井宏彦, 木村敦臣
    • Organizer
      第57回NMR討論会
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Presentation] Multiplexed HyperCEST detection of genetically-reconstituted gas vesicle nanoparticles in human cancer cells in vitro.2018

    • Author(s)
      水島良太, 井上加奈子, 永井里奈, 岩根敦子, 渡邊朋信, 木村敦臣
    • Organizer
      第57回NMR討論会
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Presentation] Quantitative evaluation of magnetic nanoparticle distribution in murine brain using magnetic particle imaging2017

    • Author(s)
      Inaoka Y, Hosoi R, Kimura A, Murase K
    • Organizer
      39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25282131
  • [Presentation] Continuous-Flow Type Production of Hyperpolarized 129Xe and Its Application to Preclinical MRI2017

    • Author(s)
      木村敦臣
    • Organizer
      大阪大学蛋白質研究所セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Presentation] Relationship between Brain and Pulmonary Function Studied by Hyperpolarized 129Xe MRI/MRS2016

    • Author(s)
      Akihiro Shimkawa, Hironobu Matsumoto, Yukiko Yamauchi, Shota Hodono, Shintaro Okumura, Neil J Stewart, Hirohiko Imai, Hideaki Fujiwara, Atsuomi Kimura.
    • Organizer
      1st AOWPFI & 8th JSPFI
    • Place of Presentation
      Awaji Yumebutai International Conference Center、兵庫県(洲本市)
    • Year and Date
      2016-01-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Presentation] Evaluation of Drug Efficacy of Ethyl Pyruvate on the Emphysema in Mice by Means of Hyperpolarized 129Xe MRI2016

    • Author(s)
      Akihiro Shimokawa, Shota Hodono, Neil J. Stewart, Hikari Ueda, Yuya Noda, Atsuomi Kimura
    • Organizer
      ICMRBS2016
    • Place of Presentation
      International Conference Center Kyoto(Kyoto)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Presentation] Evaluation of Drug Efficacy of Ethyl Pyruvate on the Pulmonary fibrosis in mice with Hyperpolarized 129Xe MRI Pulmonary Functional Diagnosis2016

    • Author(s)
      Shota Hodono, Akihiro Shimkawa, Hideaki Fujiwara, Hirohiko Imai, Atsuomi Kimura.
    • Organizer
      1st AOWPFI & 8th JSPFI
    • Place of Presentation
      Awaji Yumebutai International Conference Center、兵庫県(洲本市)
    • Year and Date
      2016-01-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Presentation] Relationship between Brain and Pulmonary Function Studied by Hyperpolarized 129Xe MRI/MRS2016

    • Author(s)
      Akihiro Shimkawa, Hironobu Matsumoto, Yukiko Yamauchi, Shota Hodono, Shintaro Okumura, Neil J Stewart, Hirohiko Imai, Hideaki Fujiwara, Atsuomi Kimura.
    • Organizer
      1st AOWPFI & 8th JSPFI
    • Place of Presentation
      Awaji Yumebutai International Conference Center、兵庫県(洲本市)
    • Year and Date
      2016-01-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Presentation] Pulmonary Functional Imaging Using Quasi-Completely Hyperpolarized 129Xe MRI2016

    • Author(s)
      Atsuomi Kimura, Akihiro Shimokawa, Shota Hodono, Yu Ozaki, Naoto Miyazaki, Hirohiko Imai, Hideaki Fujiwara
    • Organizer
      ICMRBS2016
    • Place of Presentation
      International Conference Center Kyoto(Kyoto)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Presentation] Evaluation of Drug Efficacy of Ethyl Pyruvate on the Pulmonary fibrosis in mice with Hyperpolarized 129Xe MRI Pulmonary Functional Diagnosis2016

    • Author(s)
      Shota Hodono, Akihiro Shimkawa, Hideaki Fujiwara, Hirohiko Imai, Atsuomi Kimura.
    • Organizer
      1st AOWPFI & 8th JSPFI
    • Place of Presentation
      Awaji Yumebutai International Conference Center、兵庫県(洲本市)
    • Year and Date
      2016-01-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03006
  • [Presentation] 高沸点ガスのクエンチング効果による超偏極129Xe MRIの高感度化と応用2013

    • Author(s)
      木村 敦臣, 河村 綾乃, 内山 知香, 奥村 慎太郎, 松本 浩伸, 山内 紬起子, 藤原 英明
    • Organizer
      第52回NMR討論会
    • Place of Presentation
      石川県立音楽堂
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Presentation] 超偏極129Xe MRI/MRSを用いた肺・脳機能同時測定2012

    • Author(s)
      松本浩伸、宮越友梨佳、奥村慎太郎、今井宏彦、藤原英明、木村敦叺
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      国立京都国際会議場
    • Year and Date
      2012-09-07
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Presentation] 超偏極希ガスのMRI/MRSによる肺機能診断法の開発2012

    • Author(s)
      木村敦臣
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      国立京都国際会議場(招待講演)
    • Year and Date
      2012-09-07
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Presentation] 超偏極^129Xe MRI/MRSを用いた肺・脳機能同時測定.2012

    • Author(s)
      松本浩伸、宮越友梨佳、奥村慎太郎、今井宏彦、藤原英明、木村敦臣.
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      国立京都国際会議場
    • Year and Date
      2012-09-07
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Presentation] 超偏極希ガスのMRI/MRSによる肺機能診断法の開発2012

    • Author(s)
      木村敦臣
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      国立京都国際会議場
    • Year and Date
      2012-09-07
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Presentation] 超偏極希ガスのMRI/MRSによる肺機能診断法の開発.2012

    • Author(s)
      木村敦臣
    • Organizer
      第40回日本磁気共鳴医学会大会
    • Place of Presentation
      国立京都国際会議場
    • Year and Date
      2012-09-07
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Presentation] 前臨床薬効評価へ向けた肺機能MRI2009

    • Author(s)
      木村敦臣
    • Organizer
      日本生物工学会
    • Place of Presentation
      名古屋大学 (愛知県)
    • Year and Date
      2009-09-25
    • Data Source
      KAKENHI-PROJECT-21500408
  • [Presentation] 高沸点ガスのクエンチ効果を用いた超偏極129Xe MRIの高感度化と応用

    • Author(s)
      程野祥太、山内紬起子、萩原祐、細川尚武、藤原英明、木村敦臣
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      ホテルグランヴィア京都(京都府京都市)
    • Year and Date
      2014-09-18 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Presentation] 超偏極129Xe MRI/MRSによる脳・肺機能連関に関する研究

    • Author(s)
      山内紬起子、松本浩伸、程野祥太、萩原祐、細川尚武、藤原英明、木村敦臣
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      ホテルグランヴィア京都(京都府京都市)
    • Year and Date
      2014-09-18 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-24300163
  • [Presentation] 温度感受性リポソームを用いたCEST MRI用プローブによる化学シフトの制御に関する検討

    • Author(s)
      丸山修紀, 木村敦臣, 上田淳平, 齋藤茂芳, 村瀬研也
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-09-18 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-25670532
  • 1.  FUJIWARA Hideaki (90107102)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 27 results
  • 2.  Kenya Murase (50157773)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 3.  YOSHIOKA Yoshichika (00174897)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TAKATA Hiroshige
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TAKEUCHI Tomoki
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  TAKEDA Yoshito (40452388)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  IMAI Hirohiko (40506466)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 8.  杉浦 眞喜子 (00098500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  岩崎 智宏 (50295721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  白土 優 (70379121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  近江 雅人 (60273645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  UEDA Junpei
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  SASAHARA Hisato
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YABATA Isamu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  鎌田 佳宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  渡邉 朋信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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