Horiguchi Taigo 堀口大吾

… Alternative Names

堀口大吾ホリグチタイゴ

HORIGUCHI Taigo 堀口大吾

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Researcher Number	70304532
Other IDs
Affiliation (Current)	2022: 徳島大学, 大学院医歯薬学研究部(歯学域), 助教
Affiliation (based on the past Project Information) *help	2019 – 2022: 徳島大学, 大学院医歯薬学研究部(歯学域), 助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(歯学系), 助教 2004 – 2005: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助手 2001 – 2002: 徳島大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator Functional basic dentistry Except Principal Investigator Functional basic dentistry / Pathobiological dentistry/Dental radiology / Basic Section 57020:Oral pathobiological science-related / Basic Section 57060:Surgical dentistry-related / Basic Section 57010:Oral biological science-related
Keywords	Principal Investigator 象牙質 / 石灰化 / デンチンシアロホス蛋白質 / デンチンシアロホスホ蛋白質 Except Principal Investigator ミトコンドリア / FRET / ATP / ゴーシェ病 / 重症複合型免疫不全症 / 細網異形成症 … More / AK2 / アデニル酸キナーゼ２ / アデニル酸キナーゼ / アデニンヌクレオチド / アイソザイム / ミトコンドリア膜間 / Adenylate Kinase / 口腔粘膜線維芽細胞 / exome解析 / モディファイヤー検索 / intact cell GCase assay / エクソーム解析 / データマイニング / GCase活性調節タンパク質 / SiRNA スクリーニング / in cell 酵素活性解析 / GCase結合タンパク質 / SiRNA / ハイスループット酵素活性測定系 / 細胞内局在 / 幹細胞 / エネルギー代謝 / 血球細胞分化制御 / 遺伝子変異 / 細胞分化 / 組織特異的遺伝子発現 / 制御性T細胞 / FoxP3遺伝子 / テトラサイクリン / 誘導型発現ベクター / ATP合成 / 常染色体劣性遺伝 / 酵素活性 / 構造活性相関 / adenylate kinase 2 / HL60 / 好中球 / 分化誘導 / microarray / ゲノム解析 / 好中球分化 / ATRA / ミトコンドリア機能 / ERストレス / transcriptome / genome / レチノイン酸 / 成熟停止 / 口腔がん / 分子標的治療薬 / 糖脂質分解酵素 / GCase / RNA修飾 / エピトランスクリプトーム Less

Investigation of novel oral cancer-specific molecular targets based on genetic diversity
- Principal Investigator
  
  工藤保誠
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokushima
RNA修飾による糖脂質分解酵素活性制御機構の解明とゴーシェ病克服への挑戦
- Principal Investigator
  
  三好圭子
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  The University of Tokushima
Identification of signal targets in neutrophil differentiation
- Principal Investigator
  
  NOMA TAKAFUMI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Hiroshima Jogakuin University
  The University of Tokushima
Characterization of Gaucher disease by new gene mutation using patient-derived oral mucosa fibroblasts
- Principal Investigator
  
  MIYOSHI Keiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
Study on elucidation of the pathophysiology of rare intractable diseases (reticular dysgenesis) with severe combined immunodeficiency and development of therapeutic methods
- Principal Investigator
  
  NOMA Takafumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  The University of Tokushima
Development of sensors for monitoring intracellular ATP and GTP.
- Principal Investigator
  
  NOMA Takafumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
象牙質に特異的な非コラーゲン性蛋白質の機能に関する研究Principal Investigator
- Principal Investigator
  
  堀口大吾
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima

All 2017 2015

All Journal Article Presentation

[Journal Article] Gene signature of human oral mucosa fibroblasts: comparison with dermal fibroblasts and induced pluripotent stem cells.2015
- Author(s)
  Miyoshi K, Horiguchi T, Tanimura A, Hagita H, Noma T.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 2015 Pages: 1-19
- DOI
  10.1155/2015/121575
- NAID
  120006783219
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K11041
[Presentation] CRISPR/Cas9を用いたAK2の段階的欠損による細胞代謝への影響2017
- Author(s)
  谷村綾子、三好圭子、堀口大吾、藤沢浩一、野間隆文
- Organizer
  第２回日本ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-15K11072
[Presentation] GBA 遺伝子5´側バリアントの発現パターン解析2017
- Author(s)
  三好圭子, 萩田浩子, 谷村綾子, 堀口大吾, 野間隆文
- Organizer
  2017 年度生命科学系学会合同年次大会ConBio 2017 （神戸、兵庫）
- Data Source
  KAKENHI-PROJECT-15K11041
[Presentation] ミトコンドリアがUPR活性をコントロールして免疫細胞分化の方向を決定づける2017
- Author(s)
  谷村綾子、三好圭子、堀口大吾、萩田浩子、藤沢浩一、野間隆文
- Organizer
  第17回日本ミトコンドリア学会
- Data Source
  KAKENHI-PROJECT-15K11072
[Presentation] From Molecular Structure and Mechanisms to Cellular Bioenergetics in Health and Disease2017
- Author(s)
  Tanimura A, Miyoshi K, Horiguchi T, Hagita H, Fujisawa K, Noma T
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11072

1. NOMA Takafumi (40189428)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. MIYOSHI Keiko (20304537)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. 毛利安宏 (80464353)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 谷村綾子 (10610199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 工藤保誠 (50314753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 岡本哲治 (00169153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 宮本洋二 (20200214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 萩田浩子 (30512123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Horiguchi Taigo 堀口 大吾

堀口 大吾 ホリグチ タイゴ

HORIGUCHI Taigo 堀口 大吾

Research Projects

Research Products

Co-Researchers

Investigation of novel oral cancer-specific molecular targets based on genetic diversity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNA修飾による糖脂質分解酵素活性制御機構の解明とゴーシェ病克服への挑戦

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of signal targets in neutrophil differentiation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Characterization of Gaucher disease by new gene mutation using patient-derived oral mucosa fibroblasts

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on elucidation of the pathophysiology of rare intractable diseases (reticular dysgenesis) with severe combined immunodeficiency and development of therapeutic methods

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of sensors for monitoring intracellular ATP and GTP.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

象牙質に特異的な非コラーゲン性蛋白質の機能に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gene signature of human oral mucosa fibroblasts: comparison with dermal fibroblasts and induced pluripotent stem cells.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] CRISPR/Cas9を用いたAK2の段階的欠損による細胞代謝への影響2017

Author(s)

Organizer

Data Source

[Presentation] GBA 遺伝子5´側バリアントの発現パターン解析2017

Author(s)

Organizer

Data Source

[Presentation] ミトコンドリアがUPR活性をコントロールして免疫細胞分化の方向を決定づける2017

Author(s)

Organizer

Data Source

[Presentation] From Molecular Structure and Mechanisms to Cellular Bioenergetics in Health and Disease2017

Author(s)

Organizer

Data Source

Horiguchi Taigo 堀口大吾

堀口大吾ホリグチタイゴ

HORIGUCHI Taigo 堀口大吾