TABE Yoko 田部陽子

… Alternative Names

Researcher Number	70306968
Other IDs
External Links
Affiliation (Current)	2021: 順天堂大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2019: 順天堂大学, 医学(系)研究科(研究院), 教授 2016 – 2019: 順天堂大学, 医学(系)研究科(研究院), 特任教授 2016: 順天堂大学, 医学部, 教授 2010 – 2015: 順天堂大学, 医学部, 准教授 2009: Juntendo University, 医学部, 先任准教授 2004: 順天堂大学, 医学部, 講師 2000: Juntendo University, School of Medicine, Assistant Professor, 医学部, 講師
Review Section/Research Field	Principal Investigator Biological Sciences / Hematology / Carcinogenesis / Laboratory medicine / Basic Section 52010:General internal medicine-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields Except Principal Investigator Radiation science / Laboratory medicine / Bacteriology (including mycology) / Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator 骨髄微小環境 / 急性骨髄性白血病 / アポトーシス / 高齢者 / Integrin-linked kinase / Stat3 / 骨髄間質細胞 / 慢性骨髄性白血病 / イマチニブ / CXCR4 … More Except Principal Investigator DMAG / 低酸素細胞 / 放射線増感 / Hsp90 / 17-DMAG / 低酸素環境 / NICU / MRSA / genotyping / phenotyping / 低酸素細胞放射線増感 / Hｓｐ90阻害剤 / Hsp90阻害剤 / 低酸素 / heat-shock protein 90 / パルスフィールド電気泳動法 / 薬剤感受性 / ゲノタイプ / フェノタイプ / SmaI / SstII / パルスフィールドゲル電気泳動法 / PFGL / がん幹細胞 / ヒートショックプロテイン / Sulfasalazine / グルタチオン / 低酸素放細胞射線増感 / sulfasalazine / 癌幹細胞 / 放射線増感作用 / HIF1α / HSP90阻害剤 / NETs / alarmin / 敗血症 / 抗菌ペプチド / サイトカイン / DAMPs / 細胞死 / リポ多糖 / 好中球 / 感染防御・制御 / てんかん / けいれん / 心電図 / 遺伝子 / 性差 / 症候性 / 遺伝子解析 / iPS細胞 / 神経細胞 / 遺伝子異常 / 機能解析 Less

Leukemic stem cell signatures to identify therapeutic targets of elderly acute myeloid leukemiaPrincipal InvestigatorOngoing
- Principal Investigator
  
  田部陽子
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Juntendo University
骨髄微小環境下の白血病細胞の生存戦略「代謝制御」解明による新しい高齢者がん対策Principal InvestigatorOngoing
- Principal Investigator
  
  田部陽子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Juntendo University
てんかん原因遺伝子の網羅的解析および心電図の診断有用性の検討Ongoing
- Principal Investigator
  
  藍智彦
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Juntendo University
Radiosensitization of cancer stem-like cells that thrive under hypoxic conditions
- Principal Investigator
  
  Sasai Keisuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Juntendo University
Survival of acute monocytic leukemia cells is driven by activation of fatty acid oxidation in adipocytes rich bone marrow microenvironmentPrincipal Investigator
- Principal Investigator
  
  Tabe Yoko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Juntendo University
Roles of NETs and alarmins in the pathogenesis of sepsis
- Principal Investigator
  
  NAGAOKA ISAO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Juntendo University
Hypoxic radiosensitization by DMAG, an Hsp90 inhibitor
- Principal Investigator
  
  Sasai Keisuke
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Juntendo University
Integrative genomic and proteomic analyses of low-dose ionizing radiation in EBV infected-B cellsPrincipal Investigator
- Principal Investigator
  
  TABE Yoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Carcinogenesis
- Research Institution
  Juntendo University
Tyrosine kinase inhibitor induce CML migration to stromal microenvironment through Lyn/CXCR4 interactions in lipid raftsPrincipal Investigator
- Principal Investigator
  
  TABE Yoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
AKT/ILK阻害剤の抗白血病シグナル伝達機構と分子標的療法多剤併用効果Principal Investigator
- Principal Investigator
  
  田部陽子
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Epidemiologic study on methicillin-resistant S.aureus in the medical center
- Principal Investigator
  
  IGARI Jun
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  JUTENDO UNIVERSITY

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2004 Other

All Journal Article Presentation Book

[Book] WBC differentiation Procedures2012
- Author(s)
  Yoko Tabe, Naotake Satoh, Chiaki Tanaka
- Total Pages
  69
- Publisher
  Sysmex corporation scientic affairs
- Data Source
  KAKENHI-PROJECT-24501306
[Book] 白血球分類のナビゲータ2011
- Author(s)
  田部陽子、佐藤尚武、田中千晶
- Total Pages
  61
- Publisher
  シスメックス株式会社
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] Fatty Acid Metabolism, Bone Marrow Adipocytes, and AML2020
- Author(s)
  Tabe Y, Konopleva M, Andreeff M
- Journal Title
  
  Front Oncol
  
  Volume: 10 Pages: 155-155
- DOI
  10.3389/fonc.2020.00155
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424, KAKENHI-PROJECT-19KK0221
[Journal Article] Amino acid metabolism in hematologic malignancies and the era of targeted therapy2019
- Author(s)
  Tabe Y, Lorenzi PL, Konopleva M
- Journal Title
  
  Blood
  
  Volume: 134 Pages: 1014-1023
- DOI
  10.1182/blood.2019001034
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Journal Article] Inhibition of FAO in AML co-cultured with BM adipocytes: mechanisms of survival and chemosensitization to cytarabine2018
- Author(s)
  Tabe Y, Saitoh K, Yang H, Sekihara K, Yamatani K, Ruvolo V, Taka H, Kaga N, Kikkawa M, Arai H, Miida T, Andreeff M, Spagnuolo PA, Konopleva M.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Pages: 16837-16837
- DOI
  10.1038/s41598-018-35198-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424, KAKENHI-PROJECT-18K07829, KAKENHI-PROJECT-16K19855, KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-16K01834
[Journal Article] An inhibitor of oxidative phosphorylation exploits cancer vulnerability2018
- Author(s)
  Molina Jennifer R.、Tabe Yoko、Draetta Giulio F.、Heffernan Timothy P.、Konopleva Marina、Jones Philip、Di Francesco M. Emilia、Marszalek Joseph R.et al.
- Journal Title
  
  Nature Medicine
  
  Volume: 24 Pages: 1036-1046
- DOI
  10.1038/s41591-018-0052-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Journal Article] Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in <i>CRLF2</i> rearranged and/or <i>JAK</i> driven Philadelphia chromosome–like acute B-cell lymphoblastic leukemia2018
- Author(s)
  Zhang Qi、Cai Tianyu、Cavazos Antonio、Tabe Yoko、et al.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 8027-8041
- DOI
  10.18632/oncotarget.24261
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Journal Article] Neutrophil extracellular traps induce IL-1β production by macrophages in combination with lipopolysaccharide2017
- Author(s)
  Hu Z, Murakami T, Tamura H, Reich J, Kuwahara-Arai K, Iba T, Tabe Y, Nagaoka I.
- Journal Title
  
  Int J Mol Med
  
  Volume: in press Pages: 549-558
- DOI
  10.3892/ijmm.2017.2870
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-16K08789, KAKENHI-PROJECT-17K08840, KAKENHI-PROJECT-26460538
[Journal Article] Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-12017
- Author(s)
  Sekihara K, Saitoh K, Han L, Ciurea S, Yamamoto S, Kikkawa M, Kazuno S, Taka H, Kaga N, Arai H, Miida T, Andreeff M, Konopleva M, Tabe Y.
- Journal Title
  
  Oncotarget.
  
  Volume: in press Pages: 34552-34564
- DOI
  10.18632/oncotarget.16602
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-16K19855, KAKENHI-PROJECT-16K01834, KAKENHI-PROJECT-15K08624
[Journal Article] Bone marrow adipocytes facilitate fatty acid oxidation activating AMPK and a transcriptional network supporting survival of acute monocytic leukemia cells.2017
- Author(s)
  Tabe Y, Yamamoto S, Saitoh K, Sekihara K, Monma N, Ikeo K, Mogushi K, Shikami M, Ruvolo V, Ishizawa J, Hail N Jr, Kazuno S, Igarashi M, Matsushita H, Yamanaka Y, Arai H, Nagaoka I, Miida T, Hayashizaki Y, Konopleva M, Andreeff M.
- Journal Title
  
  Cancer Research
  
  Volume: 77 Pages: 1453-1464
- DOI
  10.1158/0008-5472.can-16-1645
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-16K08976, KAKENHI-PROJECT-16K19855, KAKENHI-PROJECT-15K08624
[Journal Article] Antimicrobial cathelicidin peptide LL-37 induces NET formation and suppresses the inflammatory responses in a mouse septic model2017
- Author(s)
  Hosoda H, Nakamura K, Hu Z, Tamura H, Reich J, Kuwahara-Arai K, Iba T, Tabe Y, Nagaoaka I
- Journal Title
  
  Mol Med Reports
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] Impact of Clotting Condition on the Measurement of Circulating MicroRNAs in Serum.2016
- Author(s)
  Hayashi K, Tabe Y, Miida T.
- Journal Title
  
  Clin Lab.
  
  Volume: 62 Pages: 471-475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08653
[Journal Article] ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies.2016
- Author(s)
  Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen JE, Wang Z, Ma W, Lee HC, Orlowski R, Sarbassov dos D, Lorenzi PL, Huang X, Neelapu SS, McDonnell T, Miranda RN, Wang M, Kantarjian H, Konopleva M, Davis RE, Andreeff M.
- Journal Title
  
  Science Signaling
  
  Volume: 9
- DOI
  10.1126/scisignal.aac4380
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-26461425
[Journal Article] Pancreatic lipase activity in overnight effluent predicts high transport status in peritoneal dialysis patients.2016
- Author(s)
  Idei M, Tabe Y, Hamada C, Miyake K, Takemura H, Io H, Wakita M, Horii T, Tomino Y, Ohsaka A, Miida T.
- Journal Title
  
  Clin Chim Acta.
  
  Volume: 462 Pages: 65-70
- DOI
  10.1016/j.cca.2016.08.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08624, KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-15K19187
[Journal Article] Comparison of prothrombin time tests used in the monitoring of edoxaban and their evaluation as indicators of the reversal effect.2016
- Author(s)
  Iba T, Emmi M, Hiki M, Nagayama M, Aihara K, Tabe Y, Yuri M, Ohsaka A.
- Journal Title
  
  Int J Hematol.
  
  Volume: 103 Pages: 665-672
- DOI
  10.1007/s12185-016-1975-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08653
[Journal Article] Role of microenvironment in resistance to therapy in AML.2015
- Author(s)
  Tabe Y, Konopleva M.
- Journal Title
  
  Current Hematologic Malignancy Reports
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Ribosomal Biogenesis and Translational Flux Inhibition by the2015
- Author(s)
  Yoko Tabe, Kensuke Kojima, Shinichi Yamamoto, Kazumasa Sekihara, Hiromichi Matsushita, Richard Eric Davis, Zhiqiang Wang, Wencai Ma, Jo Ishizawa, Saiko Kazuno, Michael Kauffman, Sharon Shacham, Tsutomu Fujimura, Takashi Ueno, Takashi Miida, Michael Andreef
- Journal Title
  
  PLoS One.
  
  Volume: 10
- DOI
  10.1371/journal.pone.0137210
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08624, KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26461425
[Journal Article] Role of microenvironment in resistance to therapy in AML.2015
- Author(s)
  Tabe Y, Konopleva M.
- Journal Title
  
  Curr Hematol Malig Rep.
  
  Volume: 10 Pages: 96-103
- DOI
  10.1007/s11899-015-0253-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Journal Article] Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein2015
- Author(s)
  Ishizawa J, Kojima K, Hail N Jr, Tabe Y, Andreeff M.
- Journal Title
  
  Pharmacol & Therapeutics
  
  Volume: 153 Pages: 25-35
- DOI
  10.1016/j.pharmthera.2015.06.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-26461425
[Journal Article] Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction.2015
- Author(s)
  Iba T, Hashiguchi N, Nagaoka I, Tabe Y, Kadota K, Sato K
- Journal Title
  
  Intensive Care Medicine Experimental
  
  Volume: 3 Pages: 36-36
- DOI
  10.1186/s40635-015-0072-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460538, KAKENHI-PROJECT-25462831
[Journal Article] The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor2015
- Author(s)
  Harada M, Benito J, Yamamoto S, Kaur S, Arslan D, Ramirez S, Jacamo R, Platanias L, Matsushita H, Fujimura T, Kazuno S, Kojima K, Tabe Y, Konopleva M.
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 37930-37947
- DOI
  10.18632/oncotarget.6122
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26461425
[Journal Article] ICSH guidelines for the verification and performance of automated cell counters for body fluids.2014
- Author(s)
  Bourner G, De la Salle B, George T, Tabe Y, Baum H, Culp N, Keng TB
- Journal Title
  
  Int J Lab Hematol.
  
  Volume: in press
- DOI
  10.1111/ijlh.12196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Induction of p53-mediated transcription and apoptosis by Exportin-1 (XPO1) inhibition in mantle cell lymphoma.2014
- Author(s)
  4.Yoshimura M, Ishizawa J, Ruvolo V, Dilip A, Quintas-Cardama A, McDonnell TJ, Neelapu SS, Kwak LW, Shacham S, Kauffman M, Tabe Y, Yokoo M, Kimura S, Andreeff M, Kojima K
- Journal Title
  
  Cancer Sci. 2014;105:795-801.
  
  Volume: 105 Pages: 795-801
- DOI
  10.1111/cas.12430
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24501306, KAKENHI-PROJECT-26461425
[Journal Article] Combination of antithrombin and recombinant thrombomodulin modulates neutrophil cell-death and decreases circulating DAMPs levels in endotoxemic rats.2014
- Author(s)
  Iba T, Miki T, Hashiguchi N, Tabe Y, Nagaoka I
- Journal Title
  
  Thromb Res
  
  Volume: 134 Pages: 169-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460538
[Journal Article] Rivaroxaban attenuates leukocyte adhesion in the microvasculature and thrombus formation in an experimental mouse model of type 2 diabetes mellitus.2014
- Author(s)
  Iba T, Aihara K, Yamada A, Nagayama M, Tabe Y, Ohsaka A.
- Journal Title
  
  Thromb Res.
  
  Volume: 133 Pages: 276-280
- DOI
  10.1016/j.thromres.2013.11.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches2014
- Author(s)
  Tabe Y
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 60 Pages: 156-160
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Is the neutrophil a 'prima donna' in the procoagulant process during sepsis?2014
- Author(s)
  Iba T, Miki T, Hashiguchi N, Tabe Y, Nagaoka I.
- Journal Title
  
  Critical Care
  
  Volume: 8 Pages: 230-230
- DOI
  10.1186/cc13983
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462831, KAKENHI-PROJECT-26460538
[Journal Article] Advances in understanding the leukaemia microenvironment.2014
- Author(s)
  Tabe Y, Konopleva M.
- Journal Title
  
  Br J Haematol.
  
  Volume: 164 Pages: 767-778
- DOI
  10.1111/bjh.12725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Class IA PI3K inhibition inhibits cell growth and proliferation in mantle cell lymphoma.2014
- Author(s)
  Tabe Y, Jin L, Konopleva M, Shikami M, Kimura S, Andreeff M, Raffeld M, Miida T.
- Journal Title
  
  Acta Haematol.
  
  Volume: 131 Pages: 59-69
- DOI
  10.1159/000353164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment.2013
- Author(s)
  Jin L, Tabe Y, Lu H, Borthakur G, Miida T, Kantarjian H, Andreeff M, Konopleva M.
- Journal Title
  
  Cancer Lett.
  
  Volume: 329 Pages: 45-58
- DOI
  10.1016/j.canlet.2012.09.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590689, KAKENHI-PROJECT-24501306
[Journal Article] Neutrophil extracellular traps, damage-associated molecular2013
- Author(s)
  Iba T, Murai M, Nagaoka I, Tabe Y.
- Journal Title
  
  Acute Medicine & Surgery
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] TGF-β-neutralizing antibody 1D11 enhances cytarabine-induced apoptosis in AML cells in the bone marrow microenvironment.2013
- Author(s)
  Yoko Tabe, Yue Xi Shi, Zhihong Zeng, Linhua Jin, Masato Shikami,Yasuhito Hatanaka, Takashi Miida, Frank J. Hsu, Michael Andreeff, Marina Konopleva
- Journal Title
  
  PLOS ONE
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Meropenem as predictive risk factor for isolation of multidrug-resistant Pseudomonas aeruginosa.2013
- Author(s)
  Nakamura A, Miyake K, Misawa S, Kuno Y, Horii T, Kondo S, Tabe Y, Ohsaka A
- Journal Title
  
  J Hosp Infect
  
  Volume: 83 Pages: 153-155
- DOI
  10.1016/j.jhin.2012.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] TGF-β-neutralizing antibody 1D11 enhances cytarabine-induced apoptosis in AML cells in the bone marrow microenvironment.2013
- Author(s)
  Tabe Y, Shi YX, Zeng Z, Jin L, Shikami M, Hatanaka Y, Miida T, Hsu FJ, Andreeff M, Konopleva M.
- Journal Title
  
  PLoS One
  
  Volume: ８
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment.2013
- Author(s)
  Jin L, Tabe Y, Kojima K, Shikami M, Benito J, Ruvolo V, Wang RY, McQueen T, Ciurea SO, Miida T,
- Journal Title
  
  Mol Med (Berl)
  
  Volume: 91 Pages: 1383-1397
- DOI
  10.1007/s00109-013-1076-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Performance evaluation of the automated morphological analysis of erythrocytes by CellaVision DM96.2013
- Author(s)
  Maenou I, Tabe Y, Bengtsson HI, Ishii K, Miyake K, Horiuchi Y, Idei M, Horii T, Satoh N, Miida T,
- Journal Title
  
  Clin Lab.
  
  Volume: 59 Pages: 1413-1417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Role of stromal microenvironment in nonpharmacological resistance of CML to imatinib through Lyn/CXCR4 interactions in lipid rafts.2012
- Author(s)
  Tabe Y, Jin L, Iwabuchi K, Wang RY, Ichikawa N, Miida T, Cortes J, Andreeff M, Konopleva M.
- Journal Title
  
  Leukemia
  
  Volume: 26 Pages: 883-892
- DOI
  10.1038/leu.2011.291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590689, KAKENHI-PROJECT-24501306, KAKENHI-PROJECT-24659293
[Journal Article] Effects of PPAR γ Ligands on Leukemia2012
- Author(s)
  Tabe Y, Konopleva M. Andreeff M, Ohsaka A.
- Journal Title
  
  PPAR research
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] Role of stromal microenvironment in nonpharmacological resistance of CML to imatinib through Lyn/CXCR4 interactions in lipid rafts2012
- Author(s)
  Tabe Y, Jin L, Iwabuchi K, Wang R, Ichikawa N, Miida T, Cortes J, Andreeff M, Konopleva M.
- Journal Title
  
  Leukemia
  
  Volume: 26 Pages: 883-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] Effects of PPARγ Ligands on Leukemia.2012
- Author(s)
  Tabe Y, Konopleva M, Andreeff M, Ohsaka A.
- Journal Title
  
  PPAR Res.
  
  Volume: なし
- DOI
  10.1155/2012/483656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501306
[Journal Article] Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma2011
- Author(s)
  Jin L, Tabe Y, Kimura S, Zhou Y, Kuroda J, Asou H, Inaba T, Konopleva M, Andreeff M, Miida T.
- Journal Title
  
  Br J Cancer
  
  Volume: 104 Pages: 91-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 via Mcl-1/Noxa axis2010
- Author(s)
  Kojima K, Tabe Y, Nakakuma H.
- Journal Title
  
  Leukemia 24
  
  Pages: 33-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] MDM2 antagonist Nutlin-3 enhances bortezomib-mediated mitochondrial apoptosis in TP53-mutated mantle cell lymphoma2010
- Author(s)
  Jin L, Tabe Y, Kojima K, Zhou Y, Pittaluga S, Konopleva M, Miida T, Raffeld M.
- Journal Title
  
  Cancer Lett
  
  Volume: 229 Pages: 161-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 via Mcl-1/Noxa axis2010
- Author(s)
  Kojima K, Konopleva M, Tsao T, Andreeff M, Ishida H, Shiotsu Y, Jin L, Tabe Y, NakakumaH.
- Journal Title
  
  Leukemia
  
  Volume: 24 Pages: 33-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] The MDM2 antagonist Nutlin-3 displays anti-proliferative and pro-apoptotic activity in mantle cell lymphoma2009
- Author(s)
  Tabe Y, Sebasigari D, Jin L, Rudelius M, Davies-Hill T, Miyake K, Miida T, Pittaluga S, Raffeld M.
- Journal Title
  
  Clin. Cancer Res
  
  Volume: 15 Pages: 933-942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] 白血病診断と分子標的療法に関する検討2009
- Author(s)
  田部陽子
- Journal Title
  
  臨床病理
  
  Volume: Vol.57 No.2 Pages: 137-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] 白血病診断と分子標的療法に関する検討2009
- Author(s)
  田部陽子
- Journal Title
  
  臨床病理 57
  
  Pages: 137-145
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] Therapeutic targeting of microenvironmental interactions in leukemia : Mechanisms and approaches2009
- Author(s)
  Konopleva M, Tabe Y, Zeng Z, Andreeff M.
- Journal Title
  
  Drug Resist Updat
  
  Volume: 13 Pages: 103-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] Therapeutic targeting of microenvironmental interactions in leukemia : Mechanisms and approaches2009
- Author(s)
  Konopleva M, Tabe Y, Zeng Z, Andreeff M.
- Journal Title
  
  Drug Resist Updat 12
  
  Pages: 103-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591223
[Journal Article] Involvement of ILK-dependent Akt and STAT3 activation in integrin mediated prevention of apoptosis in APL cells.2004
- Author(s)
  Yoko TABE
- Journal Title
  
  Blood 104
- Data Source
  KAKENHI-PROJECT-16023267
[Presentation] Sulfasalazineによる低酸素放射線増感効果2020
- Author(s)
  笹井啓資齋藤香里水野利恵田部陽子
- Organizer
  第 22回菅原・大西記念　癌治療増感シンポジウム癌治療増感シンポジウム癌治療増感シンポジウム癌治療増感シンポジウム in　奈良
- Data Source
  KAKENHI-PROJECT-16K10402
[Presentation] Cell adhesion to mesenchymal stem cells mediates resistance to oxidative phosphorylation inhibition in acute myeloid leukemia2019
- Author(s)
  Haeun Yang, Kaori Saitoh, Junichi Imoto, Kazuho Ikeo, Takashi Miida, Yoko Tabe
- Organizer
  International Symposium on Technical Innovations in Laboratory Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Inhibiting mitochondria function by Bcl-2 inhibitor venetoclax and complex I inhibitor IACS-010759 eliminate leukemia cells in pre-clinical AML models2019
- Author(s)
  Qi Zhang, Alessia Lodi, Lina Han, Tianyu Cai, Vinitha M. Kuruvilla, Antonio Cavazos, Helen Ma, Yoko Tabe, Joseph R. Marszalek Stefano Tiziani, Marina Konopleva
- Organizer
  61th American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Molecular mechanisms of resistance to OxPhos inhibition in AML2019
- Author(s)
  Haeun Yang, Kaori Saitoh, Junichi Imoto, Kazuho Ikeo, Takashi Miida, Yoko Tabe
- Organizer
  24th Annual Meeting of Japan Society of Gene and Cell Therapy
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Cell adhesion to BM stromal cells confers resistance to OXPHOS inhibition in AML2019
- Author(s)
  Haeun Yang, Kaori Saitoh, Junichi Imoto, Kazuho Ikeo, Takashi Miida, Yoko Tabe
- Organizer
  81th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] OxPhos inhibition induces formation of tunneling nanotubes in AML cells and facilitates mitochondrial transfer from BM stroma to AML that contributes to microenvironment-mediated drug-resistance of AML2019
- Author(s)
  Haeun Yang, Yoko Tabe, Kaori Saitoh, Kotoko Yamatani, Rodrigo Jacamo, Helen Ma, Vivian Ruvolo, Qi Zhang, Vinitha Kuruvilla, Natalia Baran, Junichi Imoto, Kazuho Ikeo, Kaori Moriya, Yuko Murakami-Tonami, Koya Suzuki, Takashi Miida, Michael Andreeff, Christopher P. Vellano, Joseph R. Marszalek, Marina Konopleva
- Organizer
  61th American Society of Hematology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Tunneling nanotubes formation as a mechanism of microenvironment-induced resistance to OxPhos inhibition in AML2019
- Author(s)
  Yoko Tabe, Haeun Yang, Kaori Saito, Rodrigo Jacamo, Helen Ma, Vivian Ruvolo, Junichi Imoto , Kazuho Ikeo, Kotoko Yamatani, Takashi Miida, Yoshihide Hayashizaki, Michael Andreeff, Joseph Marszalek, Marina Konopleva
- Organizer
  MD Anderson Cancer Center GAP 2019 conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Fatty acid metabolism and bone marrow adipocytes in AML2019
- Author(s)
  Yoko Tabe
- Organizer
  ESH 3rd Scientific Workshop on Haematological Tumour Microenvironment and its Therapeutic Targeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Tunneling NanoTubes formation as a mechanism of microenvironment-induced resistance to OxPhos inhibition in AML2019
- Author(s)
  Yoko Tabe
- Organizer
  Annual GAP Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Metabolic inhibition and mitochondrial transfer caused by OXPHOS inhibition in AML2019
- Author(s)
  Kaori Saitoh, Haeun Yang, Yuko Murakami-Tonami Y, Koya Suzuki, Takashi Miida. Yoko Tabe
- Organizer
  81th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Novel Oxidative phosphorylation inhibitor IACS-010759 inhibits p38MAPK-NFkB signaling pathways.2018
- Author(s)
  Tabe Y, Yang H, Sekihara K, Saitoh K, Ma H, Ruvolo V, Imoto J, Ikeo K, Mogushi K, Hosoya M, Hayashizaki Y, Yamanaka Y, Miida T, Andreeff M, Marszalek JR, Konopleva M.
- Organizer
  GAP 2018 Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Mitochondrial transfer confers microenvironment-mediated resistance to OxPhos inhibition in AML.2018
- Author(s)
  Yang H, Tabe Y, Saitoh K, Jacamo R, Ma H, Ruvolo V, Imoto J, Ikeo K, Mogushi K, Hosoya M, Yamaguchi S, Yamatani K, Murakami-Tonami Y, Suzuki K, Miida T, Andreeff M, Marszalek JR, Konopleva M.
- Organizer
  60th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07424
[Presentation] Inhibition of FAO in AML co-cultured with BM adipocytes: mechanisms of survival and chemosensitization to cytarabine.2017
- Author(s)
  Yoko Tabe, Kazumasa Sekihara, Haeun Yang, Kaori Saito, Vivian Ruvolo, Hikari Taka, Naoko Kaga, Takashi Miida, Michael Andreeff, Paul A Spagnuolo, Marina Konopleva.
- Organizer
  59th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Novel Oxidative Phosphorylation Inhibitor Iacs-010759 Induces AMPK-Dependent Apoptosis of AML Cells.2017
- Author(s)
  Haeun Yang, Yoko Tabe, Kazumasa Sekihara, Kaori Saito, Helen Ma, Vivian Ruvolo, Junichi Imoto, Kazuho Ikeo, Kaoru Mogushi, Masaki Hosoya1, Yoshihide Hayashizaki, Yasunari Yamanaka, Takashi Miida, Michael Andreeff, Joseph R Marszalek, and Marina Konopleva
- Organizer
  59th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] XPO1 Inhibition Targets Transcriptional Vulnerability of FLT3-ITD+D835 Double Mutant AML through p53 Accumulation and Inhibition of Oncogenic Transcription Factors: Lesson Learned from Cage Sequencing of Primary AML Cells.2017
- Author(s)
  Kotoko Yamatani, Yoko Tabe, Kazumasa Sekihara, Haeun Yang, Kaori Saito, Weiguo Zhang, Kazuho Ikeo , Sonoko Kinjo, Kaoru Mogushi, Masaki Hosoya1, Yoshihide Hayashizaki, Yasunari Yamanaka, Hironori Harada, Takashi Miida, Marina Konopleva, and Michael Andreeff
- Organizer
  59th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Bone marrow adipocytes facilitate fatty acid oxidation activating AMPK and a transcriptional network supporting survival of acute monocytic leukemia cells.2017
- Author(s)
  Yoko Tabe
- Organizer
  Annual GAP Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] BCL-2 Antagonist ABT-199 Combined with Complex I Inhibitor Iacs-010759 Blocks Mitochondrial Respiration and Facilitates Anti-Leukemia Efficacy in Pre-Clinical AML Models.2017
- Author(s)
  Qi Zhang, Lina Han, Tianyu Cai, Vinitha Mary Kuruvilla, Antonio Cavazos, Helen Ma, Venkata Lokesh Battula, Natalia Baran, Karine Harutyunyan, Michael Andreeff, Yoko Tabe, Joseph R Marszalek, Marina Konopleva
- Organizer
  9th American Society of Hematology Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Cap analysis of gene expression (CAGE) sequencing reveals alterations of the transcriptional signatures of FLT3-ITD with secondary D835 TKD mutations in acute myeloid leukemia.2016
- Author(s)
  Yoko Tabe, Kazumasa Sekihara, Kaori Saitoh, Norikazu Monma, Kazuho Ikeo, Bogumil Kaczkowski, Weiguo Zhang, Yasunari Yamanaka, Takashi Miida, Neil P. Shah, Hironori Harada, Yoshihide Hayashizaki, Marina Konopleva, Michael Andreeff.
- Organizer
  58th American Society of Hematology (ASH) Annual Meeting and Exposition.
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] The simultaneous blockade of mTOR and nuclear transporter exportin-1 induces synergistic antitumor effect through pro-survival metabolism in mantle cell lymphoma.2016
- Author(s)
  Kazumasa Sekihara, Kaori Saitoh, Takashi Miida, Michael Andreeff, Marina Konopleva, Yoko Tabe.
- Organizer
  Society of Hematologic Oncology Fourth Annual Meeting.
- Place of Presentation
  Houston, USA
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Novel fatty acid oxidation inhibitor avocatinB induces AMPK-dependent apoptosis of AML cells co-cultured with BM-adipocytes.2016
- Author(s)
  Yoko Tabe, Kazumasa Sekihara, Kaori Saitoh, Vivian Ruvolo, Takashi Miida, Michael Andreeff, Paul A. Spagnuolo, Marina Konopleva.
- Organizer
  58th American Society of Hematology (ASH) Annual Meeting and Exposition.
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Novel flowcytometry-based approach to detect tumor cells in body fluid using Sysmex automated hematology analyzer.2016
- Author(s)
  Akimichi Ohsaka, Hiroyuki Takemura, Toshihiro Takahashi, Konobu Kimura, Aya Konishi, Takashi Horii, Takashi Miida, Yoko Tabe.
- Organizer
  68th AACC Annual Scientific Meeting & Clinical Lab Expo.
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2016-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Novel flowcytometry-based approach of tumor cells detection in body fluid using Sysmex automated hematology analyzer.2016
- Author(s)
  Yoko Tabe, Toshihiro Takahashi, Hiroyuki Takemura, Konobu Kimura, Aya Konishi, Takashi Horii, Takashi Miida, Akimichi Ohsaka.
- Organizer
  29th International Symposium on Technological Innovations in Laboratory Hematology.
- Place of Presentation
  Milano, Italy
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] ONC201 Induces p53-Independent Apoptosis and Abrogates Stem Cell Function in Hematological Malignancies By Induction of ATF4 through Integrated Stress Response2015
- Author(s)
  Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Tabe Y, Allen J, Wang Z, Ma W, Lee H, Orlowski RZ, Sarbassov DD, Neelapu SS, McDonnell TJ, Miranda RN, Wang M, Kantarjian HM, Konopleva M, Eric Davis R, Andreeff M:
- Organizer
  57th American Society of Hematology (ASH) Annual Meeting and Exposition.
- Place of Presentation
  Orlando　（アメリカ）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Cap analysis of gene expression (CAGE) sequencing reveals alterations of the transcript signatures in acute monocytic leukemia cells by fatty acid oxidation inhibition2015
- Author(s)
  Yoko Tabe, Marina Konopleva, Norikazu Monma, Kazuho Ikeo, Kaoru Mogushi, Yasunari Yamanaka, Hiromichi Matsushita, Takashi Miida, Yoshihide Hayashizaki, Michael Andreeff.
- Organizer
  57th American Society of Hematology (ASH) Annual Meeting and Exposition.
- Place of Presentation
  Orlando（アメリカ）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Novel FAO inhibitor avocatin B induces apoptosis of acute monocytic leukemia cells in adipocyte co-culture system via ER stress and ATF4 activation.2015
- Author(s)
  Yoko Tabe, Shinichi Yamamoto, Mika Kikkawa, Hikari Taka, Naoko Kaga, Kaoru Mogushi, Hiromichi Matsushita, Takashi Miida, Michael Andreeff, Paul A. Spagnuolo6 Marina Konopleva.
- Organizer
  57th American Society of Hematology (ASH) Annual Meeting and Exposition.
- Place of Presentation
  Orlando　（アメリカ）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Inactivating Heat Shock Factor 1 (HSF1) in Acute Myeloid Leukemia By Pharmacological Inhibition of eIF4a: A Promising Therapeutic Approach.2015
- Author(s)
  Jo Ishizawa, Rodrigo Omar Jacamo, Kensuke Kojima, Dhruv Chachad, Vivian Ruvolo, Peter Ruvolo, Weiguo Zang, Yoko Tabe, Marina Konopleva, William Devine, Susan Lindquist, John A Porco, Luke Whitesell, Michael Andreeff:
- Organizer
  57th American Society of Hematology (ASH) Annual Meeting and Exposition.
- Place of Presentation
  Orlando　（アメリカ）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] mTOR kinase inhibitor AZD-2014 enhances the antitumor effects of XPO1 antagonist KPT-185 in mantle cell lymphoma.2015
- Author(s)
  Kazumasa Sekihara, Shinichi Yamamoto, Mika Kikkawa, Hikari Taka, Naoko Kaga, Hiromichi Matsushita, Takashi Miida, Michael Andreeff, Marina Konopleva, Yoko Tabe
- Organizer
  European Society for Medical Oncology (ESMO) Asia 2015 Congress
- Place of Presentation
  Singapore　（シンガポール）
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Combined Targeting of JAK2 with a Type II JAK2 Inhibitor and mTOR with a TOR Kinase Inhibitor Constitutes Synthetic Activity in JAK2-Driven Ph-like Acute Lymphoblastic Leukemia2015
- Author(s)
  Ce Shi, Lina Han, Qi Zhang, Kathryn G. Roberts, Eugene Park, Yoko Tabe, Rodrigo Omar Jacamo, Hong Mu, Shuo-Chieh Wu, Jin Zhou, Helen Ma1, Zhihong Zeng, Nitin Jain, Elias J Jabbour, Markus Muschen1, Sarah K Tasian, Charles G. Mullighan, David M. Weinstock, David Fruman, Marina Konopleva,.
- Organizer
  57th American Society of Hematology (ASH) Annual Meeting and Exposition.
- Place of Presentation
  Orlando　（アメリカ）
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08653
[Presentation] Molecular mechanisms of adipocyte-leukemia interactions revealed by the quantitative proteomics technology: pro-survival function of adipocyte-derived free fatty acids on acute monoblastic leukemia mitochondrial biogenesis.2013
- Author(s)
  Tabe Y, Jin L, Kazuno S, Fujimura T, Matsushita H, Ueno T, Miida T, Andreeff M, Konopleva M.
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Efficacy of the internet-based e-leaning system using the CellaVision Competency Software for continuing professional development.2013
- Author(s)
  Tabe Y, Ishii K, Kasuga K, Maenoh I, Horii T, Miida T, Ohsaka A.
- Organizer
  26th International Symposium on Technological Innovations in Laboratory Hematology.
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Molecular mechanisms of inhibition of ribosomal biogenesis and translational flux by the Selective Inhibitor of Nuclear Export (SINE) XPO1/CRM1 antagonist KPT-185 in mantle cell lymphoma.2013
- Author(s)
  Tabe Y, Kojima K, Jin L, Iwanami H, Matsushita H, Kazuno S, Kauffman M, Shacham S, Fujimura T,
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Integrative genomic and proteomic analysis of low-dose ionizing irradiation effects on bone marrow stromal microenvironment and on survival of pre-leukemic cells.2013
- Author(s)
  Tabe Y, Jin L, Hatanaka Y, Matsushita H, Kazuno S, Fujimura T, Ueno T, Sasai K, Iwabuchi K, Andreeff M, Konopleva M, Miida T
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Detection of tumor cells in body fluids by the automated morphological analysis system CellaVision DM96 following the automated cell counting by the Sysmex XE5000.2013
- Author(s)
  Takemura H, Tabe Y, Yamaguchi K, Ishii K, Kasuga K, Horii T, Miida T, Ohsaka A.
- Organizer
  American Association for Clinical Chemistry Annual Meeting
- Place of Presentation
  Houston,　USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Metabolic shift in hypoxia-adapted CML cells and mechanisms of acquired dasatinib resistance uncovered by proteomic iTRAQ profiling.2013
- Author(s)
  Tabe Y, Jin L, Iwanami H, Matsushita H, Kazuno S, Fujimura T, Ueno T, Miida T, Andreeff M, Konopleva M, Kimura S.
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Efficacy and mechanisms of the mTOR inhibitor AZD2014 combined with L-Asparaginase or JAK2 inhibitor TG101348 in ALL.2013
- Author(s)
  Tabe Y, Jin L, Iwanami H, Matsushita H, Kazuno S, Fujimura T, Ueno T, Miida T, Weinstock D, Thomas DA, Andreeff M, Konopleva M.
- Organizer
  55th American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Performance evaluation of a novel high-risk Human Papilloma Virus Genotyping test (Clinichip HPV™).2013
- Author(s)
  Yamada H, Tabe Y, Ishii K, Terao Y, Takeda S, Horii T, Ohsaka A.
- Organizer
  American Association for Clinical Chemistry Annual Meeting.
- Place of Presentation
  Houston,　USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] The clinical significance of mesothelial cell in peritoneal dialysis effluent detected by Cellavision DM96.2013
- Author(s)
  Idei M, Tabe Y, Miyake K, Hamada C, Takemura H, Io H, Ishii K, Horii T, Tomino Y, Ohsaka A, Miida T.
- Organizer
  American Association for Clinical Chemistry Annual Meeting
- Place of Presentation
  Houston,　USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Molecular Mechanisms of Antitumor Activity of the Selective Inhibitor of Nuclear Export (SINE) CRM1 Antagonist KPT-185 in Mantle Cell Lymphoma.2012
- Author(s)
  Yoko Tabe, Kensuke Kojima, Linhua Jin, Takashi Miida, Shacham S, Kauffman M, Michaell Andreeff.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Analysis of Dasatinib-Induced Molecular Mechanisms of Apoptosis in Hypoxia-Adopted CML Cells Utilizing Quantitative Proteomics Technology.2012
- Author(s)
  Yoko Tabe, Linhua Jin, Hiroko Iwanami, Kazuno S, Fujimura T, Hiromichi Matsushita, Takashi Ueno, Takashi Miida, Michaell Andreeff, Marina Konopleva, Shinya Kimura.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Molecular Mechanisms of Pro-Survival and Differentiating Function of Bone Marrow-Derived Adipocytes On Acute Monoblastic Leukemia Cells.2012
- Author(s)
  Linhua Jin, Marina Konopleva, Masato Shikami, Takako Ikegami, Kensuke Kojima , MichaellAndreeff, Takashi Miida, Yoko Tabe
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] TGF-beta1 Supports Leukemia Cell Survival Via Negative Regulation of FLI-1 Transcription Factor, ERK Inactivation and MMP-1 Secretion.2012
- Author(s)
  Yoko Tabe, Linhua Jin, Yasuhito Hatanaka, Takashi Miida, Steven Kornblau, Michaell Andreeff, Marina Konopleva.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  Atlanta,USA
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] 低線量放射線被爆による生体微小環境内の発がん誘導機序．2012
- Author(s)
  田部陽子, 金林花, 畑中康人, 松下弘道, 笹井啓資, 三井田孝
- Organizer
  放射線影響学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Bone marrow-derived adipocytes promote differentiation, proliferation and survival of acute monoblastic leukemia cells2011
- Author(s)
  Tabe Y, Jin L, Konopleva M, Andreeff M, Ohsaka A, Miida T.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] The anti-proliferative effects of tricyclic coumarin GUT-70 as an Hsp90 inhibitor in mantle cell lymphoma2011
- Author(s)
  Jin L, Kimura S, Zhou Y, Kuroda J, Asou H, Inaba T, Miida T, Konopleva M, Andreeff M, Tabe Y.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] マントル細胞リンパ腫の分子標的2011
- Author(s)
  田部陽子
- Organizer
  東海大学悪性リンパ腫研究会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] 低酸素骨髄微小環境下での残存白血病に対するPI3KとFLT3.阻害の抗腫瘍作用機序2011
- Author(s)
  田部陽子、金林花、三井田孝
- Organizer
  日本臨床検査医学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] 低酸素骨髄微小環境下での残存白血病に対するPI3KとFLT3.阻害の抗腫瘍作用機序2011
- Author(s)
  田部陽子, 他
- Organizer
  日本臨床検査医学会総会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] Growth-inhibitory effects of a Class IA PI3K inhibitor GDC-0941 are modulated by hypoxia-induced mTOR pathway activation in mantle cell lymphoma2011
- Author(s)
  Tabe Y, Jin L, Miida T, Andreeff M, Konopleva M.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] TGF-βneutralizing antibody 1D11 inhibits LIF-JAK-Stat3 signaling and enhances cytarabine induced apoptosis in AML cells in bone marrow microenvironment2011
- Author(s)
  Tabe Y, Shi Y, Zeng Z, Jin L, Zhou Y, Miida T, Andreeff M, Konopleva M.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] 白血病細胞の増殖、分化、細胞死および骨髄微小循環2011
- Author(s)
  田部陽子
- Organizer
  前臨床血液研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] 白血病細胞の増殖、分化、細胞死および骨髄微小環境2011
- Author(s)
  田部陽子
- Organizer
  日本検査血液学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] TGF-β neutralizing antibody 1D11 inhibits LIF-JAK-Stat3 signaling and enhances cytarabine induced apoptosis in AML cells in bone marrow microenvironment2011
- Author(s)
  Tabe Y, 他
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] B Growth-inhibitory effects of a Class IA PI3K inhibitor GDC-0941 are modulated by hypoxia-induced mTOR pathway activation in mantle cell lymphoma2011
- Author(s)
  Tabe Y, 他
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] 白血病細胞の増殖、分化、細胞死および骨髄微小環境2011
- Author(s)
  田部陽子
- Organizer
  シーメンスヘマトロジーセミナー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] The Anti-Proliferative Effects of Tricyclic Coumarin GUT-70 as An Hsp90 Inhibitor In Mantle Cell Lymphoma2010
- Author(s)
  Jin L, Kimura S, Zhou Y, Kuroda J, Asou H, Inaba T, Andreeff M, Miida T, Tabe Y.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] Role of Stromal Microenvironment In Non-Pharmacological Resistance of CML to Tyrosine Kinase Inhibitors through Lyn/CXCR4 Interactions In Lipid Rafts2010
- Author(s)
  Yoko Tabe, et al
- Organizer
  52^<nd> Annual Meeting of American Society of Hematology
- Place of Presentation
  Orlando, U.S.A.
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] MDM2 antagonist nutlin-3 enhances bortezomib-mediated mitochondrial apoptosis in TP53-mutated mantle cell lymphoma2010
- Author(s)
  Tabe Y, Jin L, Kojima K, Zhou Y, Pittaluga S, Konopleva M, Miida T, Raffeld M.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] Efficacy and Mechanisms of Apoptosis Induction by Simultaneous Inhibition of PI3K with GDC-0941 and Blockade of Bcl-2(ABT-737) or FLT3(Sorafenib) In AML Cells In the Hypoxic Bone Marrow Microenvironment2010
- Author(s)
  Jin L, Tabe Y, Miida T, Andreeff M, Konopleva M.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] Inhibition of TGF-βand CXCR4 signaling promotes cell cycle arrest and apoptosis in leukemic cells co-cultured with stromal cells2010
- Author(s)
  Zhou Y, Tabe Y, Jin L, Miida T, Zeng Z, Andreeff M, Konopleva M.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] マントル細胞リンパ腫に対するプロテアソーム阻害剤BortezomibとMDM2阻害剤Nutlin-3の抗腫瘍相乗効果2009
- Author(s)
  田部陽子, 金林花, 周奕欣, 三井田孝
- Organizer
  第56回日本臨床検査医学会学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] Selective FLT3 Inhibitor FI-700 Neutralizes Mcl-1 and Enhances p53-Mediated Apoptosis in Acute Myeloid Leukemia(AML) Cells with Activating Mutations of FLT3 Via Mcl-1/Noxa Axis New Orleans2009
- Author(s)
  Kojima K, Konopleva M, Tsao T, Andreeff M, Ishida H, Shiotsu Y, Jin L, Tabe Y, Nakakuma H.
- Organizer
  Annual Meeting of American Society of Hematology(ASH)
- Place of Presentation
  San Francisco, U. S. A
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] The Tricyclic Coumarin GUT-70 Induces Apoptosis and Cell Cycle Arrest Preferentially in Mantle Cell Lymphomas with Mutant p53 New Orleans2009
- Author(s)
  Jin L, Kimura S, Zhou Y, Kuroda J, Asou H, Inaba T, Andreeff M, Miida T, Tabe Y.
- Organizer
  Annual Meeting of American Society of Hematology(ASH)
- Place of Presentation
  San Francisco, U. S. A
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] チロシンキナーゼ阻害剤による慢性骨髄性白血病のCXCR4シグナル活性化と骨髄定着2009
- Author(s)
  金林花、周奕欣、田部陽子、三井田孝
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] PTEN Regulates SYK-Directed AKT Activation in MCL New Orleans2009
- Author(s)
  Rudelius M, Pittaluga S, Sebasigari D, Davies-Hill T, Klier M, Quintanilla-Martinez L, Fend F, Tabe Y, Raffeld M.
- Organizer
  Annual Meeting of American Society of Hematology(ASH)
- Place of Presentation
  San Francisco, U. S. A
- Data Source
  KAKENHI-PROJECT-21591223
[Presentation] Metabolic re-programming in Notch-activated T-ALL by mTOR inhibitor AZD2014 combined with L-Asparaginase.
- Author(s)
  Yoko Tabe, Masako Harada, Yuka Miyamae, Tsutomu Fujimura, Saiko Kazuno, Takashi Ueno, Takashi Miida, Michael Andreeff, Marina Konopleva.
- Organizer
  56th American Society of Hematology Annual Meeting
- Place of Presentation
  San Francisco,USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Pro-survival effects of TGF-β1 are associated with molecular signaling changes of ERK, FLI-1, and CD44 in AML cells.
- Author(s)
  Yoko Tabe, Yasuhito Hatanaka, Peter Ruvolo, Takashi Miida, Steve Kornblau, Michael Andreeff, Marina Konopleva.
- Organizer
  56th American Society of Hematology Annual Meeting
- Place of Presentation
  San Francisco,USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Molecular mechanisms of inhibition of ribosomal biogenesis and translational flux by the Selective Inhibitor of Nuclear Export (SINE) XPO1/CRM1 antagonist KPT-185 in mantle cell lymphoma
- Author(s)
  Yoko Tabe, Kensuke Kojima, Linhua Jin, Hiroko Iwanami, Hiromichi Matsushita, Saiko Kazuno, Michael Kauffman, Sharon Shacham, Tsutomu Fujimura, Takashi Ueno, Takashi Miida, Michael Andreeff
- Organizer
  Global Academic Programs 2014 Annual Conference
- Place of Presentation
  Soule, Korea
- Year and Date
  2014-05-01 – 2014-05-03
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Bone marrow adipocyte-derived free fatty acids induce gene signature linking transcription with metabolic changes that contribute to survival of acute monocytic leukemia cells
- Author(s)
  Yoko Tabe, Masako Harada, Yuka Miyamae, Kaoru Mogushi, Saiko Kazuno, Tsutomu Fujimura, Hiromichi Matsushita, Takashi Ueno, Takehiko Yokomizo, Takashi Miida, Ismael Samudio, Michael Andreeff, Marina Konopleva.
- Organizer
  56th American Society of Hematology Annual Meeting
- Place of Presentation
  San Francisco,USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] Selective inhibitor of nuclear export selinexor (KPT-330) and BCL2 inhibitor ABT-199 enhance the anti-lymphoma effect of BTK inhibitor ibrutinib in mantle cell lymphoma.
- Author(s)
  Yoko Tabe, Masako Harada, Yuka Miyamae, Saiko Kazuno, Tsutomu Fujimura, Takashi Ueno, Takashi Miida, Marina Konopleva, Michael Andreeff
- Organizer
  56th American Society of Hematology Annual Meeting
- Place of Presentation
  San Francisco,USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24501306
[Presentation] The mTOR kinase inhibitor AZD-2014 effectively reverses XPO1/CRM1 antagonist KPT-185–induced glycolysis / gluconeogenesis, enhancing antitumor effects in mantle cell lymphoma.
- Author(s)
  Yoko Tabe, Masako Harada, Yuka Miyamae, Hiromichi Matsushita, Kensuke Kojima, Tsutomu Fujimura, Saiko Kazuno, Takashi Ueno, Takashi Miida, Marina Konopleva, Michael Andreeff
- Organizer
  56th American Society of Hematology Annual Meeting
- Place of Presentation
  San Francisco,USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-24501306

1. SASAI Keisuke (20225858)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. 三井田孝 (80260545)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
3. JIN Linhua (90531955)

# of Collaborated Projects: 2 results

# of Collaborated Products: 35 results
4. IWABUCHI Kazuhisa (10184897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 藍智彦 (00570128)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TOMIKAWA Naoki (80468587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. IGARI Jun (20053100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAGAOKA ISAO (60164399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 石井裕子 (00251546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 西園寺克 (60138344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 桑原京子 (10167976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 射場敏明 (40193635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. 森周介 (20362072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 赤松和土 (60338184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 鈴木浩也 (40788551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 早津徳人 (80543058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ASAHINA Taito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HU Zhongshuang

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. TAKA Hikari

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. KAGA Naoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. UENO Tsuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. KUWAHARA Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. KONO Masaomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 関原和正

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
25. 小島研介

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
26. 出居真由美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 松下弘道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TABE Yoko 田部 陽子

田部 陽子 タベ ヨウコ

Research Projects

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Leukemic stem cell signatures to identify therapeutic targets of elderly acute myeloid leukemiaPrincipal InvestigatorOngoing

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骨髄微小環境下の白血病細胞の生存戦略「代謝制御」解明による新しい高齢者がん対策Principal InvestigatorOngoing

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てんかん原因遺伝子の網羅的解析および心電図の診断有用性の検討Ongoing

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Radiosensitization of cancer stem-like cells that thrive under hypoxic conditions

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Survival of acute monocytic leukemia cells is driven by activation of fatty acid oxidation in adipocytes rich bone marrow microenvironmentPrincipal Investigator

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Roles of NETs and alarmins in the pathogenesis of sepsis

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Hypoxic radiosensitization by DMAG, an Hsp90 inhibitor

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Integrative genomic and proteomic analyses of low-dose ionizing radiation in EBV infected-B cellsPrincipal Investigator

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Tyrosine kinase inhibitor induce CML migration to stromal microenvironment through Lyn/CXCR4 interactions in lipid raftsPrincipal Investigator

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AKT/ILK阻害剤の抗白血病シグナル伝達機構と分子標的療法多剤併用効果Principal Investigator

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Epidemiologic study on methicillin-resistant S.aureus in the medical center

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[Book] WBC differentiation Procedures2012

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[Book] 白血球分類のナビゲータ2011

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TABE Yoko 田部陽子

田部陽子タベヨウコ

[Journal Article] Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in <i>CRLF2</i> rearranged and/or <i>JAK</i> driven Philadelphia chromosome–like acute B-cell lymphoblastic leukemia2018