Sawai Nobuhiko 澤井信彦

… Alternative Names

SAWAI Nobuhiko 澤井信彦

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Researcher Number	70307916
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2017: 日本医科大学, 医学部, 講師 2014: 群馬大学, 医学(系)研究科(研究院), 助教 2012: 日本医科大学, 医学部, 助教 2011: 群馬大学, 大学院・医学研究科, 助教 2010: 日本医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Environmental physiology(including physical medicine and nutritional physiology) Except Principal Investigator General anatomy (including histology/embryology) / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords	Principal Investigator ニューロキニンB / NPFF receptor / kisspeptin receptor / 室傍核 / キスペプチン / 甲状腺刺激ホルモン放出ホルモン / axonal projection / hypothalamus / receptor expression / network … More / sex hormone / thyroliberin / prolactin / neurokinin B / kisspeptin … More Except Principal Investigator バソプレッシン / 培養細胞 / アクアポリン3 / 腎臓 / 脱リン酸化 / リン酸化 / アクアポリン2 / ストレス応答調節 / 摂食制御調節 / 性機能調節 / 思春期 / 生殖神経内分泌 / 遺伝子発現 / 摂食調節 / 性差 / 性ステロイド / キスペプチン / glucocorticoid receptor / CRH / 生殖機能調節 / ストレス応答 / 星状膠細胞 / TIDA neuron / Kisspeptin / グルココルチコイド受容体 / レプチン / エネルギー代謝 / ストレス / 視床下部 / GnRH / HPG 軸 / キスペプチン(kisspeptin) Less

Studies on molecules controlling aqaporin-2 trafficking and its mechanism.
- Principal Investigator
  
  Matsuzaki Toshiyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Gunma University
Verifying the regulation of reproductive physiology by kisspeptin through thyroliberin.Principal Investigator
- Principal Investigator
  
  Sawai Nobuhiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Nippon Medical School
  Gunma University
Study on the dynamic morphofunctional relationships between the neuronal regulation of reproduction, energy control, and stress response in the onset of puberty
- Principal Investigator
  
  OZAWA Hitoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nippon Medical School

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] <b>Phosphorylation and dephosphorylation of aquaporin-2 at serine 269 and its subcellular distribution during vasopressin-induced exocytosis and subsequent endocytosis in the rat </b><b>kidney </b>2017
- Author(s)
  Kinue Shimizu, Megumi Sano, Aoi Kita, Nobuhiko Sawai, Akiko Iizuka-Kogo, Hiroshi Kogo, Takeo Aoki, Kuniaki Takata, Toshiyuki Matsuzaki
- Journal Title
  
  Archives of Histology and Cytology
  
  Volume: 77 Issue: 1 Pages: 25-38
- DOI
  10.1679/aohc.77.25
- NAID
  130006182300
- ISSN
  0914-9465, 1349-1717
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08461, KAKENHI-PROJECT-16K08462, KAKENHI-PROJECT-26460267
[Journal Article] Neurokinin B- and kisspeptin-positive fibers as well as tuberoinfundibular dopaminergic neurons directly innervate periventricular hypophyseal dopaminergic neurons in rats and mice.2014
- Author(s)
  Sawai N, Iijima N, Ozawa H, Matsuzaki T
- Journal Title
  
  Neurosci Res.
  
  Volume: 84 Pages: 10-18
- DOI
  10.1016/j.neures.2014.05.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460316, KAKENHI-PROJECT-26460323
[Journal Article] Regulation of tuberoinfundibulardopamine (TIDA) neurons by kisspeptin neurons2012
- Author(s)
  Ozawa H., Sawai N., Iwata K., Takumi K., Iijima N
- Journal Title
  
  J Nippon Med Sch
  
  Volume: 79 Pages: 168-9
- NAID
  130004147159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] Immunofluorescent histochemical and ultrastructural studies on the innervation of kisspeptin/neurokini B neurons to tuberoinfundibular dopaminergic neurons in the arcuate nucleus of rats2012
- Author(s)
  Nobuhiko Sawai
- Journal Title
  
  Neuroscience Research
  
  Volume: 74 Issue: 1 Pages: 10-16
- DOI
  10.1016/j.neures.2012.05.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] Immuno- fluorescent histochemical and ultrastractural studies on the innervation of kisspeptin/ neurokinin B neurons to tuberoinfundibular dopaminergic neurons in the arcuate nucleus2012
- Author(s)
  Sawai N., Iijima N., Takumi K., Matsuzaki T., Ozawa H
- Journal Title
  
  Neurosci Res
  
  Volume: 74 Pages: 10-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] Immunohistochemical localization of water channels, AQP4 and AQP5 in the rat pituitary gland2011
- Author(s)
  Matsuzaki T., Inahata Y., Sawai N.,Yang C-Y., Kobayashi M., Takata K.,Ozawa H
- Journal Title
  
  Acta Histochem Cytochem
  
  Volume: 44 Pages: 259-266
- NAID
  130001258488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] 新規生理活性物質キスペプチンKisspeptinと性機能調節神経系～新しい間脳(視床下部)-下垂体-性腺系機能概念の構築2011
- Author(s)
  小澤一史、託見健、澤井信彦、岩田衣世、中根亮、飯島典生
- Journal Title
  
  顕微鏡
  
  Volume: 46(2) Pages: 111-118
- NAID
  10029694620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] The general anesthetic sevoflurane affects the expression of clock gene mPer2 accompanying the change of NAD+ level in the suprachiasmatic nucleus of mice2011
- Author(s)
  Iijima N., Takumi K., Sawai N., Ozawa H
- Journal Title
  
  An immunohistochemical study on the exressional dynamics of kisspeptin neurons relevant to GnRH neurons using anewly developed anti-kisspeptin antibody
  
  Volume: 46 Issue: 2 Pages: 146-154
- DOI
  10.1007/s12031-010-9433-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] An immunohistochemical study on the exressional dynamics of kisspeptin neurons relevant to GnRH neurons using a newly developed anti-kisspeptin antibody.2011
- Author(s)
  Iijima N., Takumi K., Sawai N., Ozawa H.
- Journal Title
  
  Journal of Molecular Neruoscience
  
  Volume: 43 Pages: 146-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] An immunohistochemical study on the exressional dynamics of kisspeptin neurons relevant to GnRH neurons using anewly developed anti-kisspeptin antibody2011
- Author(s)
  Iijima N., Takumi K., Sawai N., Ozawa H
- Journal Title
  
  J. Mol Neruoscience
  
  Volume: 43 Pages: 146-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] The influence of dietary restriction on the development of diabetes and pancreatitis in female WBN/Kob-fatty rats.2010
- Author(s)
  Akimoto T., Terada M., Shimizu A., Sawai N., Ozawa H.
- Journal Title
  
  Experimental Animals
  
  Volume: 59 Pages: 623-630
- NAID
  130000419257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] The influence of dietary restriction on the development of diabetes and pancreatitis in female WBN/Kob-fatty rats2010
- Author(s)
  Akimoto T., Terada M., Shimizu A., Sawai N., Ozawa H
- Journal Title
  
  Experimental Animals
  
  Volume: 59 Pages: 623-630
- NAID
  130000419257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] Developmental and aging change of orexin-A and -B immuno-reactive neurons in the male rat hypothalamus.2010
- Author(s)
  Sawai N., Ueta Y., Nakazato M., Ozawa H.
- Journal Title
  
  Neuroscience Letter
  
  Volume: 468 Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Journal Article] Developmental and aging change of orexin-A and -B immunoreactive neurons in the male rat hypothalamus2010
- Author(s)
  Sawai N., Ueta Y., Nakazato M., Ozawa H
- Journal Title
  
  Neurosci Lett
  
  Volume: 468 Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] ラット視床下部ドーパミンニューロンへの蛍光標識キスペプチンを用いたin vivo binding assay法の検討2016
- Author(s)
  澤井信彦、瀧澤俊広
- Organizer
  第121回日本解剖学会総会
- Place of Presentation
  福島県郡山市
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26460316
[Presentation] 胎仔期から乳仔期マウスの造血系におけるアクアポリンの発現変化2015
- Author(s)
  喜多碧，向後寛，向後晶子，澤井信彦，松崎利行
- Organizer
  日本解剖学会関東支部第103回学術集会
- Place of Presentation
  慶應義塾大学日吉キャンパス（神奈川県横浜市）
- Year and Date
  2015-08-05
- Data Source
  KAKENHI-PROJECT-26460267
[Presentation] アクアポリンの発現と機能的意義―下垂体の幹・前駆細胞ニッチにおける発現も含め－2014
- Author(s)
  松崎利行，澤井信彦，小澤一史
- Organizer
  日本下垂体研究会第29回学術集会
- Place of Presentation
  八王子セミナーハウス（東京都八王子市）
- Year and Date
  2014-08-09
- Data Source
  KAKENHI-PROJECT-26460267
[Presentation] ラット視床下部におけるkisspeptin/neurokinin Bによるプロラクチン分泌制御系の探索2013
- Author(s)
  澤井信彦
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] Kisspeptinニューロンによる視床下部Tuberoinfundibular dopamine(TIDA)ニューロンの制御2012
- Author(s)
  飯島典生、澤井信彦、岩田衣世、松本恵介、小澤一史
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  甲府
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] キスペプチンによるラット視床下部神経内分泌性ドーパミンニューロンのドーパミン合成能変化2012
- Author(s)
  澤井信彦、飯島典生、小澤一史、松崎利行
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  甲府
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] Regulation of the Tuberoinfundibular Dopamine Neuron by Kisspeptin in the Rat Hypothalamus2012
- Author(s)
  Iijima N., Sawai N., Iwata K., Matsumoto K., Ozawa H
- Organizer
  2 nd World Conference of Kisspeptin Signaling in the Brain
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 雌ラット視床下部におけるTH陽性細胞へのキスペプチン線維投射の分布と超微形態学的解析2011
- Author(s)
  澤井信彦、飯島典生、小澤一史
- Organizer
  第88回日本生理学会大会/第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜、神奈川県
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 雌ラット視床下部におけるTH陽性細胞へのキスペプチン線維投射の分布と超微形態学的解析2011
- Author(s)
  澤井信彦、飯島典生、小澤一史
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 神経ペプチドkisspeptin含有神経線維の視床下部Tuberoinfundibulardopamineneuronsへの入力2011
- Author(s)
  飯島典生、澤井信彦、岩田衣世、中根亮、松本恵介、小澤一史
- Organizer
  第52回日本組織細胞化学会総会・学術集会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] KisspeptinニューロンとGnRHあるいはDopamineニューロンとの相互作用に関する機能形態学的研究2011
- Author(s)
  飯島典生、澤井信彦、託見健、岩田衣世、国村有弓、中根亮、松本恵介、小澤一史
- Organizer
  第88回日本生理学会大会/第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜、神奈川県
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] Immunohistchemical study on the kisspeptin neurons in the rat brain using a newly developed anti-kisspeptin antibody.2011
- Author(s)
  Ozawa H., Sawai N., Takumi K.Iwata K., Nakane R., MatsumotoK., Iijima N.
- Organizer
  6^<th> International Meeting Steroids and Nervous System
- Place of Presentation
  Torino. Italy
- Year and Date
  2011-02-22
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 視床下部Tuberoinfundibular dopamine neuronsによる神経ペプチドkisspeptin含有神経線維からの入力・応答2011
- Author(s)
  飯島典生、澤井信彦、岩田衣世、松本恵介、小澤一史
- Organizer
  第38回日本神経内分泌学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 神経ペプチドkisspeptin含有神経線維の視床下部Tuberoinfundibular dopamine neuronsへの入力2011
- Author(s)
  飯島典生、澤井信彦、岩田衣世, 中根亮、松本恵介、小澤一史
- Organizer
  第52回日本組織細胞化学会総会・学術集会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 視床下部Tuberoinfundibular dopami neneuronsによる神経ペプチドkisspeptin含有神経線維からの入力・応答2011
- Author(s)
  飯島典生、澤井信彦、岩田衣世、松本恵介、小澤一史
- Organizer
  第38回日本神経内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 弓状核ドーパミンニュートロンを介した神経ペプチドkisspeptinの新たな生理作用2010
- Author(s)
  飯島典生、澤井信彦、岩田衣世、松本恵介、小澤一史
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 雌ラット視床下部弓状核ドーパミン産生ニューロンへのkisspeptin神経線維入力2010
- Author(s)
  澤井信彦、飯島典生、松本恵介、小澤一史
- Organizer
  第37回日本神経内分泌学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] A novel input of kisspeptin fibers to dopaminergic neurons in the arcuate nucleus of female rat.2010
- Author(s)
  Sawai N., Iijima N., Matsumoto K., Ozawa H.
- Organizer
  The 7^<th> International Congress of Neuro-endocrinology
- Place of Presentation
  Rouen. France
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 雌ラット視床下部弓状核ドーパミン産生ニューロンへのkisspeptin神経線維入力2010
- Author(s)
  澤井信彦、飯島典生、松本恵介、小澤一史
- Organizer
  第37回日本神経内分泌学会学術集会
- Place of Presentation
  京都、京都府
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 神経ペプチドkisspeptinの視床下部背側弓状核における新規神経回路2010
- Author(s)
  飯島典生、澤井信彦、岩田衣世、中根亮、松本恵介、小澤一史
- Organizer
  第37回日本神経内分泌学会学術集会
- Place of Presentation
  京都、京都府
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] Reexamination of the expression and the distribution of kisspeptin neurons in the rat using a newly developed antibody.2010
- Author(s)
  Iijima N., Sawai N., Takumi K., Matsumoto K., Tobari Y., Ozawa H.
- Organizer
  The 7^<th> International Congress of Neuro-endocrinology
- Place of Presentation
  Rouen. France
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] 弓状核ドーパミンニュートロンを介した神経ペプチドkisspeptinの新たな生理作用2010
- Author(s)
  飯島典生、澤井信彦、岩田衣世、松本恵介、小澤一史
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸、兵庫県
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22590230
[Presentation] Prolactin-regulating dopaminergic neurons in the hypothalamus express neurokinin-B receptor and are innervated by neurokinin B- and kisspeptin-immunopositive fibers in rodents.
- Author(s)
  Sawai N, Iijima N, Ozawa H, Matsuzaki T
- Organizer
  The International Congress of Neuroendocrinology
- Place of Presentation
  オーストラリア、シドニー
- Year and Date
  2014-08-17 – 2014-08-20
- Data Source
  KAKENHI-PROJECT-26460316

1. IIJIMA Norio (00285248)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
2. Matsuzaki Toshiyuki (30334113)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. OZAWA Hitoshi (60169290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 29 results
4. YO Shunei (70303435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 託見健 (40553269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. 向後寛 (20282387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 向後晶子 (20340242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 青木武生 (70150919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sawai Nobuhiko 澤井 信彦

SAWAI Nobuhiko 澤井 信彦

Research Projects

Research Products

Co-Researchers

Studies on molecules controlling aqaporin-2 trafficking and its mechanism.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Verifying the regulation of reproductive physiology by kisspeptin through thyroliberin.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the dynamic morphofunctional relationships between the neuronal regulation of reproduction, energy control, and stress response in the onset of puberty

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] <b>Phosphorylation and dephosphorylation of aquaporin-2 at serine 269 and its subcellular distribution during vasopressin-induced exocytosis and subsequent endocytosis in the rat </b><b>kidney </b>2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Neurokinin B- and kisspeptin-positive fibers as well as tuberoinfundibular dopaminergic neurons directly innervate periventricular hypophyseal dopaminergic neurons in rats and mice.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of tuberoinfundibulardopamine (TIDA) neurons by kisspeptin neurons2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Immunofluorescent histochemical and ultrastructural studies on the innervation of kisspeptin/neurokini B neurons to tuberoinfundibular dopaminergic neurons in the arcuate nucleus of rats2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immuno- fluorescent histochemical and ultrastractural studies on the innervation of kisspeptin/ neurokinin B neurons to tuberoinfundibular dopaminergic neurons in the arcuate nucleus2012

Author(s)

Journal Title

Data Source

[Journal Article] Immunohistochemical localization of water channels, AQP4 and AQP5 in the rat pituitary gland2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 新規生理活性物質キスペプチンKisspeptinと性機能調節神経系～新しい間脳(視床下部)-下垂体-性腺系機能概念の構築2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The general anesthetic sevoflurane affects the expression of clock gene mPer2 accompanying the change of NAD+ level in the suprachiasmatic nucleus of mice2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An immunohistochemical study on the exressional dynamics of kisspeptin neurons relevant to GnRH neurons using a newly developed anti-kisspeptin antibody.2011

Author(s)

Journal Title

Data Source

[Journal Article] An immunohistochemical study on the exressional dynamics of kisspeptin neurons relevant to GnRH neurons using anewly developed anti-kisspeptin antibody2011

Author(s)

Journal Title

Data Source

[Journal Article] The influence of dietary restriction on the development of diabetes and pancreatitis in female WBN/Kob-fatty rats.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The influence of dietary restriction on the development of diabetes and pancreatitis in female WBN/Kob-fatty rats2010

Author(s)

Sawai Nobuhiko 澤井信彦

SAWAI Nobuhiko 澤井信彦