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Yamagata Kazutsune  山形 和恒

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YAMAGATA Kazutsune  山形 和恒

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Researcher Number 70311412
Affiliation (Current) 2025: 藤田医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2020 – 2023: 国立研究開発法人国立がん研究センター, 研究所, 研究員
2012: 独立行政法人国立がん研究センター, 研究所, 研究員
2008 – 2009: 国立がんセンター(研究所及び東病院臨床開発センター), 分子腫瘍学部, 研究員
2007: 国立がんセンター研究所, 分子腫瘍学部, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related
Except Principal Investigator
Hematology
Keywords
Principal Investigator
脂質代謝 / SREBF1 / 急性骨髄性白血病 / MLL-ENL / スクリーニング / 分子標的 / 予後不良化
Except Principal Investigator
白血病 / 幹細胞 / NPMc … More / NPM / YB-1 / nucleophosmin / acute myeloid leukemia / 血液腫瘍学 / PML / 細胞分化 / GATA / PU.1 / MOZ / 造血幹細胞 / 転写制御 Less
  • Research Projects

    (4 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (4 People)
  •  脂質代謝経路を介した急性骨髄性白血病の発症、及び予後不良化メカニズムの解明Principal Investigator

    • Principal Investigator
      山形 和恒
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      National Cancer Center Japan
  •  Isolation of molecular targets for AML with poor prognosisPrincipal Investigator

    • Principal Investigator
      Yamagata Kazutsune
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      National Cancer Center Japan
  •  Development of the novel AML treatments by targeting leukemia stem cells

    • Principal Investigator
      KITABAYASHI Issay
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      National Cancer Center Japan
  •  Study for regulatory mechanism of normal and leukemic stem cells through transcription factors

    • Principal Investigator
      KITABAYASHI Issay
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2010 2009 2008 Other

All Journal Article Presentation

  • [Journal Article] Sirtl physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX2010

    • Author(s)
      Yamagata K, et al.
    • Journal Title

      Biochem Biophys Res Commun 390

      Pages: 1355-1360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390268
  • [Journal Article] Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX.2009

    • Author(s)
      Yamagata K, Kitabayashi I.
    • Journal Title

      Biochem Biophys Res Commun 390

      Pages: 1355-1360

    • Data Source
      KAKENHI-PROJECT-19390268
  • [Journal Article] Roles of AML1/RUNX1 in T-cell malignancy induced by loss of p53.

    • Author(s)
      Shimizu K, Yamagata K, Kurokawa M, Mizutani S, Tsunematsu Y, Kitabayashi I
    • Journal Title

      Cancer Sci.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390197
  • [Presentation] PU.1-mediated upregulation of CSF1R/cFMSIM-CSFR is critical for MOZ- and MLL-leukemia stem cell potential2008

    • Author(s)
      Yukiko Aikawa, Takuo Katsumoto, Naomi Yoshida, Kazutsune Yamagata, Akihiko Yokoyama, Issay Kitabayashi
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-19390268
  • 1.  ROKUDAI Susumu (50469970)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  YOSHIDA Hitoshi (10506710)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  KITABAYASHI Issay (20261175)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  WATANABE Toshio (60201208)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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