Uozumi Naonori 魚住尚紀

… Alternative Names

UOZUMI Naonori 魚住尚紀

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Researcher Number	70313096
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2011 – 2013: 埼玉医科大学, 医学部, 講師 2002 – 2004: The University of Tokyo, Graduate School of Medicine, Research Associate, 大学院・医学系研究科, 助手 2001: Japan Society for the Promotion of Science, Researcher, 特別研究員 2000: 東大, 医学(系)研究科, 助手 1999 – 2000: 東京大学, 大学院・医学系研究科, 助手
Review Section/Research Field	Principal Investigator Immunology / Pathological medical chemistry / Pathological medical chemistry Except Principal Investigator Respiratory organ internal medicine / Biological Sciences / Biological Sciences / Functional biochemistry
Keywords	Principal Investigator 自然免疫受容体 / 炎症 / 免疫学 / 破骨細胞 / 関節炎 / プロスタグランジン / 炎症性サイトカイン / 疾患モデル / 生理活性脂質 / ロイコトリエン / プロスグランジン / ホスホリパーゼA2 … More Except Principal Investigator … More PAF / ARDS / 血小板活性化因子 / Transgenic mouse / Knockout mouse / ノックアウトマウス / ロイコトリエン / ホスホリパーゼA2 / CGRP / LPS / Gタンパク共役型受容体 / 脂質メディエーター / トランスジェニックマウス / ロイコトリエンB4 / 5-リポキシゲナーゼ / Pulmonary surfactant lipids / Metabolome / Knockout mice (or Gene-deficient mice) / G protein-coupled receptor / Phospholipase A2 / Platelet-activating factor / Acyltransferase / Lipid mediator / Gタンパク共役型受容 / ロイトコリエン / 質量分析計 / ロイトコイエン / アシル転位酵素 / 肺サーファクタント脂質 / メタボローム / 遺伝子欠損マウス / アシル転移酵素 / カルシトニン遺伝子関連ペプチド / エンドトキシン / 急性呼吸窮迫症候群 / allegy / phospholipase A2 / leukotrienes / inflammation / lung fibrosis / arachidonic acid / Lipid mediators / ロイコトリエンC / 脂質メディエータ / 生合成 / SNP / ホスホリパーゼA_2 / 神経発生 / 神経可塑性 / 受容体 / ホスホリバーゼA2 / シグナル伝達 / アラキドン酸 / トランスジェニツクマウス / 顆粒放出 / フォスホリパーゼ / クローニング / G-タンパク質共役型受容体 / 気管支喘息 / BLT2 / BLT1 / MAPキナーゼ / cPLA2 / ホスホリパーゼ / 妊娠分娩障害 / 炎症性疾患 / 生理活性脂質 Less

Analysis of structure-function relationship of mouse TLR5 with a focus on roles of LRRCT domainPrincipal Investigator
- Principal Investigator
  
  UOZUMI Naonori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Saitama Medical University
生理活性脂質産生を介した細胞質型ホスホリパーゼA2の生体における機能の解明Principal Investigator
- Principal Investigator
  
  魚住尚紀
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Lipid Mediators and Lipid Metaborome
- Principal Investigator
  
  SHIMIZU Takao
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
ロイコトリエン合成・代謝酵素、ロイコトリエン受容体を介したマスト細胞活性化の機序
- Principal Investigator
  
  YOKOMIZO Takehiko
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
遺伝子改変マウスを用いたホスホリパーゼA2の生理的機能の解析Principal Investigator
- Principal Investigator
  
  魚住尚紀
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Roles and regulation of lipid mediators
- Principal Investigator
  
  SHIMIZU Takao
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Molecular mechanisms underlying ARDS and development of novel therapeutic strategies using genetically-engineered mice
- Principal Investigator
  
  NAGASE Takahide
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Novel therapeutic straetgies to inflammatory lung diseases using genetically-engineering technique : roles of eicosanoids and PAF
- Principal Investigator
  
  NAGASE Takahide
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
ノックアウトマウスを使ったcPLA2の機能解析と新規PLA2の検索
- Principal Investigator
  
  IZUMI Takashi, 粂和彦
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (B)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
  The University of Tokyo

All 2013 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] 単量型マウスＴＬＲ４による細胞内情報伝達の分子機序と意義の解明2013
- Author(s)
  魚住尚紀
- Journal Title
  
  埼玉医科大学雑誌
  
  Volume: 40 Pages: 48-51
- Data Source
  KAKENHI-PROJECT-23590572
[Journal Article] 単量型マウスTLR4による細胞内情報伝達の分子機序と意義の解明2013
- Author(s)
  魚住尚紀
- Journal Title
  
  埼玉医科大学雑誌
  
  Volume: 40 Pages: 48-51
- Data Source
  KAKENHI-PROJECT-23590572
[Journal Article] Group IVA phospholipase A(2)-mediated production of fibronectin by oxidized LDL in mesangial cells.2006
- Author(s)
  Akiba, S., Mukaida, Y., Hane, K., Oka, M., Uozumi, N., Shimizu, T., Sato, T.
- Journal Title
  
  Kidney Int. 70
  
  Pages: 1013-1018
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Group IVA phospholipase A(2)-mediated production of fibronectin by oxidized LDL in mesangial cells.2006
- Author(s)
  Akiba, S., Mukaida, Y., Hane, K., Oka, M., Uozumi, N., Shimizu, T., Sato, T.
- Journal Title
  
  Kidney Int 70
  
  Pages: 1013-1018
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Biochemical properties and pathophysiological roles of cytosolic phospholipase A2s.2006
- Author(s)
  Kita, Y., Ohto, T., Uozumi, N., Shimizu, T.
- Journal Title
  
  Biochim. Biophys. Acta 1761
  
  Pages: 1317-1322
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] A multiplex quantitation method for eicosanoids and platelet-activating factor using column-switching reversed-phase liquid chromatography-tandem mass spectrometry.2005
- Author(s)
  Kita, Y., Takahashi, T., Uozumi, N., Shimizu, T.
- Journal Title
  
  Analytical Biochemistry 342
  
  Pages: 134-143
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Protective role for cytosolic phospholipase A2alpha in autoimmune diabetes of mice.2005
- Author(s)
  Oikawa, Y., Yamato, E., Tashiro, F., Yamamoto, M., Uozumi, N., Shimada, A., Shimizu, T., Miyazaki, J.
- Journal Title
  
  FEBS Letter. 579
  
  Pages: 3975-3978
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoid production without activation of cytosolic phospholipase A2.2005
- Author(s)
  Saiga, A., Uozumi, N., Ono, T., Seno, K., Ishimoto, Y., Arita, H., Shimizu, T., Hanasaki, K.
- Journal Title
  
  Prostaglandins Other Lipid Med. 75
  
  Pages: 79-89
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Pathway-orient ed profiling of lipid mediators in macrophages.2005
- Author(s)
  Kita, Y., Takahashi, T. . Uozumi, N., Nallan, L., Gelb, M. H., Shimizu, T
- Journal Title
  
  Biochem. Biophys. Res. Commun. 330
  
  Pages: 898-906
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoidproduction without activation of cytosolic phospholipase A2.2005
- Author(s)
  Saiga, A. . Uozumi, N., Ono, T., Seno, K., Ishimoto, Y., Arita, H., Shimizu, T. ., Hanasaki. K.
- Journal Title
  
  Prostaglandins Other Lipid Med. 75
  
  Pages: 79-89
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Group X secretory phospholipase A2 can induce arachidonic acid release and eicosanoid production without activation of cytosolic, phospholipase A2.2005
- Author(s)
  Saiga, A., Uozumi, N., Ono, T., Seno, K., Ishimoto, Y., Arita, H., Shimizu, T., Hanasaki, K.
- Journal Title
  
  Prostaglandins and Other Lipid Mediators 46
  
  Pages: 839-862
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Pathway-oriented profiling of lipid mediators in macrophages.2005
- Author(s)
  Kita, Y., Takahashi, T., Uozumi, N., Nallan, L., Gelb, M. H., Shimizu, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 330
  
  Pages: 898-906
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Identification of novel cytosolic phospholipase A2s. murine cPLA2 delta, epsilon, and zeta, which form a gene cluster with cPLA2 beta.2005
- Author(s)
  Ohto, T., Uozumi, N., Hirabayashi, T., Shimizu, T.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 24576-24583
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] A multiplex quantitation method for eicosanoids and platelet-activating factor using column-switching reversed-phase liquid chromatography-tandem mass spectrometry・2005
- Author(s)
  Kita, Y., Takahashi, T., Uozumi, N., Shimizu, T.
- Journal Title
  
  Anal. Biochem. 342
  
  Pages: 134-143
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Cytosolic phospholipase A2a-deficient mice are resistant to experimental autoimmune encephalomyelitis2005
- Author(s)
  Marusic, S., Leach, M.W., Pelker, J.W., Azoitei, M.L., Uozumi, N., Cui, J., DeClercq, C.M., Shen, M.W.H., Miyashiro, J.S., Carito, B.A., Thakker, P., Simmons, D.L., Leonard, J.P., Shimizu, T., Clark, J.D.
- Journal Title
  
  Journal of Experimental Medicine 202
  
  Pages: 841-851
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Identification of novel cytosolic phospholipase A2s, murine cPLA2 delta, epsilon, and zeta, which form a gene cluster with cPLA2 beta.2005
- Author(s)
  Ohto, T., Uozumi, N., Hirabayashi, T., Shimizu, T.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 24576-24583
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Protective role for cytosolic phospholipase A2alpha in autoimmune diabetes of mice.2005
- Author(s)
  Oikawa, Y., Yamato, E., Tashiro, F., Yamamoto, M., Uozumi, N., Shimada, A., Shimizu T. ., Miyazaki, J.
- Journal Title
  
  FEBS Lett. 579
  
  Pages: 3975-3978
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Identification of novel cytosolic phospholipase A2s, murine cPLA2 delta, epsilon, and zeta, which form a gene cluster with cPLA2 beta.2005
- Author(s)
  Ohto, T., Uozumi, N., Hirabayashi, T., Shimizu, T.
- Journal Title
  
  Journal of Biological Chemistry 280
  
  Pages: 24576-24583
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Cytosolic phospholipase A2alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis.2005
- Author(s)
  Marusic, S., Leach, M. W., Pelker, J. W., Azoitei, M. L., Uozumi, N., Cui, J., DeClercq, C. M., Shen, M. W. H., Miyashiro, J. S., Carito, B. A., Thakker, P., Simmons, D. L., Leonard, J. P., Shimizu, T., Clark, J. D.
- Journal Title
  
  J. Exp. Med. 202
  
  Pages: 841-851
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Pathway-oriented profiling of lipid mediators in macrophages.2005
- Author(s)
  Kita, Y., Takahashi, T., Uozumi, N., Nallan, L., Gelb, M.H., Shimizu, T.
- Journal Title
  
  Biochemical and Biophysical Research Communications 330
  
  Pages: 898-906
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Cytosolic phospholipase A2alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis.2005
- Author(s)
  Marusic, S., Leach, M, W, Pelker, J. w., Azoitei, M. L., Uozumi, N., Cui, J., DeClercq, CM., Shen, M. W. H., Miyashiro, J. S., Carito, B. A., Thakker, P., Simmons, D. L., Leonard, J. P., Shimizu, T., Clark, J. D.
- Journal Title
  
  J. Exp. Med. 202
  
  Pages: 841-851
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] A multiplex quantitation method for eicosanoids and platelet-activating factor using column-switching reversed-phase liquid chromatography-tandem mass spectrometry.2005
- Author(s)
  Kita, Y., Takahashi, T., Uozumi, N., Shimizu, T.
- Journal Title
  
  Anal. Biochem. 342
  
  Pages: 134-143
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Protective role for cytosolic phospholipase A2alpha in autoimmune diabetes of mice.2005
- Author(s)
  Oikawa, Y., Yamato, E., Tashiro, F., Yamamoto, M., Uozumi, N., Shimada, A., Shimizu, T., Miyazaki, J.
- Journal Title
  
  FEBS Lett. 579
  
  Pages: 3975-3978
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A32004
- Author(s)
  Tashiro, S., Sumi, T., Uozumi, N.et al.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 17715-17722
- Data Source
  KAKENHI-PROJECT-15790162
[Journal Article] Lethal malaria in cytosolic phospholipase A2- and phospholipase IIA-deficient mice.2004
- Author(s)
  Ishikawa, S., Uozumi, N., et al.
- Journal Title
  
  J.Tropical Med Hyg. 70
  
  Pages: 645-650
- Data Source
  KAKENHI-PROJECT-15790162
[Journal Article] Cytosolic Phospholipase A2 ・ deficient Mice Are Resistant to Collagen-induced Arthritis2003
- Author(s)
  Hegen, M., Sun L., Uozumi N., Kume K., Goad, E. M., Nickerson-Nutter L. C., Shimizu T., Clark D. J.
- Journal Title
  
  J. Exp. Med. 197
  
  Pages: 1297-1302
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] An Essential Role of Cytosolic Phospholipase A2 ・ in Prostaglandin E2-mediated Bone Resorption Associated with Inflammation2003
- Author(s)
  Miyaura, C., Inada, M., Matsumoto, C., Ohshiba, C., Uozumi, N., Shimizu, T., Ito, A.
- Journal Title
  
  J. Exp. Med. 197
  
  Pages: 1303-1310
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] B-Myb-dependent regulation of c-Myc expression by cytosolic phospholipase A2.2003
- Author(s)
  Tashiro, S., Sumi, T., Uozumi, N., Shimizu, T., Nakamura, T.
- Journal Title
  
  J. Biol. Chem. 279
  
  Pages: 17715-17722
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15002004
[Journal Article] Cytosolic Phospholipase A2 ・ deficient Mice Are Resistant to Collagen-induced Arthritis2003
- Author(s)
  Hegen, M., Sun L., Uozumi N., Kume K., Goad, E. M., Nickerson-Nutter L. C, Shimizu T., Clark D. J.
- Journal Title
  
  J. Exp. Med. 197
  
  Pages: 1297-1302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15002004
[Presentation] 変異体を用いたマウスTLR4, 5活性化機構の解析2013
- Author(s)
  魚住尚紀、村越隆之
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-23590572
[Presentation] 変異体を用いたマウスTLR4, 5活性化機構の解析
- Author(s)
  魚住尚紀、村越隆之
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590572

1. YOKOMIZO Takehiko (60302840)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. ISHII Satoshi (10300815)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. IZUMI Takashi (70232361)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SHIMIZU Takao (80127092)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
5. NAGASE Takahide (40208004)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TANIGUCHI Masahiko (70260346)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KURIHARA Hiroki (20221947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAKAMURA Motonao (40431762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. SHINDOU Hideo (10401027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KITA Yoshihiro (20401028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. TAKAHASHI Toshie (80236299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. 粂和彦 (30251218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 大日方英 (50332557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 田口良 (20080210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 奥野利明 (60361466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Uozumi Naonori 魚住 尚紀

UOZUMI Naonori 魚住 尚紀

Research Projects

Research Products

Co-Researchers

Analysis of structure-function relationship of mouse TLR5 with a focus on roles of LRRCT domainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生理活性脂質産生を介した細胞質型ホスホリパーゼA2の生体における機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lipid Mediators and Lipid Metaborome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ロイコトリエン合成・代謝酵素、ロイコトリエン受容体を介したマスト細胞活性化の機序

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遺伝子改変マウスを用いたホスホリパーゼA2の生理的機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles and regulation of lipid mediators

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms underlying ARDS and development of novel therapeutic strategies using genetically-engineered mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel therapeutic straetgies to inflammatory lung diseases using genetically-engineering technique : roles of eicosanoids and PAF

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ノックアウトマウスを使ったcPLA2の機能解析と新規PLA2の検索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] 単量型マウスＴＬＲ４による細胞内情報伝達の分子機序と意義の解明2013

Author(s)

Journal Title

Data Source

[Journal Article] 単量型マウスTLR4による細胞内情報伝達の分子機序と意義の解明2013

Author(s)

Journal Title

Data Source

[Journal Article] Group IVA phospholipase A(2)-mediated production of fibronectin by oxidized LDL in mesangial cells.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Group IVA phospholipase A(2)-mediated production of fibronectin by oxidized LDL in mesangial cells.2006

Author(s)

Journal Title

Data Source

[Journal Article] Biochemical properties and pathophysiological roles of cytosolic phospholipase A2s.2006

Author(s)

Journal Title

Description

Uozumi Naonori 魚住尚紀

UOZUMI Naonori 魚住尚紀