HAYASHI Yasuhito 林康人

… Alternative Names

林康人ハヤシヤスヒト

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Researcher Number	70314953
Affiliation (Current)	2025: 愛媛大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2019 – 2023: 愛媛大学, 医学部, 研究員 2017 – 2018: 愛媛大学, 医学系研究科, 研究員 2012 – 2016: 愛媛大学, 医学部附属病院, 講師 2011: 愛媛大学, 医学(系)研究科(研究院), 講師 2010 – 2011: 愛媛大学, 大学院・医学系研究科, 准教授(寄附講座教員) 2000: 愛媛大, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Ophthalmology / Ophthalmology Except Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology
Keywords	Principal Investigator 再生医療 / バイオイメージング / 角膜実質 / ケラトサイト / 遺伝子組み換えマウス / Fucci / 透明治癒 / 骨髄線維芽細胞 / gene targeting / bio-imaging … More / keratocyte / keratocan / 幹細胞 / ドキシサイクリン / 上皮 / 眼瞼 / 線維芽細胞増殖因子７ / 遺伝子組換えマウス / ドライアイ / 性ホルモン / 線維芽細胞増殖因子7 / マイボーム腺 … More Except Principal Investigator バイオイメージング / ケラトサイト / 透明治癒 / 角膜実質 / 細胞増殖 / 角膜実質混濁 / ZFP521 / 遺伝子組み換えマウス / レックリングハウゼン病 / 骨髄細胞 / Creレポーターマウス / Fucci / 再生医療 / 骨髄線維芽細胞 / 遺伝子組換えマウス / K12遺伝子 / stem cell / 幹細胞 / 角膜上皮 / K12 Less

Establishment of therapeutic strategy for corneal stromal scaring treatment by applying the ZFP521 gene.
- Principal Investigator
  
  白石敦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Ehime University
Establishment of therapeutic strategy for corneal stromal scaring treatment by applying the NF1 (von Recklinghausen disease) gene.
- Principal Investigator
  
  Shiraishi Atsushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Ehime University
Bone marrow mesenchymal cell transplantation for corneal stroma regenerationPrincipal Investigator
- Principal Investigator
  
  Hayashi Yasuhito
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Ehime University
Bone Marrow Mesenchymal Cell Transplantation for thin Corneal Stroma
- Principal Investigator
  
  Yuichi Ohashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Ehime University
Bio-imaging for Cornea stromal Stem Cell BiologyPrincipal Investigator
- Principal Investigator
  
  Hayashi Yasuhito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Ehime University
Analysis of Krt12 gene expression mechanism
- Principal Investigator
  
  OHASHI Yuichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Ehime University
Sex Hormone Effect on FGF7 Signaling andApplication for Dry EyePrincipal Investigator
- Principal Investigator
  
  HAYASHI Yasuhito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Ehime University
移植羊膜の細胞接着と血管新生および瘢痕化抑制効果の基礎研究Principal Investigator
- Principal Investigator
  
  林康人
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Ophthalmology
- Research Institution
  Ehime University

All 2016 2015 2014 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] The "replacement hypothesis": corneal stem cell origin epithelia are replaced by limbal stem cell origin epithelia in mouse cornea during maturation2012
- Author(s)
  Hayashi Y, Watanabe N, Ohashi Y
- Journal Title
  
  Cornea
  
  Volume: 31
- Data Source
  KAKENHI-PROJECT-23592608
[Journal Article] Involvement of stem cell factor and c-kit in corneal wound healing inmice2012
- Author(s)
  Miyamoto, K., Kobayashi, T., Hayashi, Y., Zhang, Y., Hara, Y., Higashine, M., Shiraishi, A., Ohashi, Y
- Journal Title
  
  Mol Vis
  
  Volume: 18 Pages: 1505-1515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591943
[Journal Article] Bone marrow mesenchymal stem cells can differentiate and assume corneal keratocyte phenotype2012
- Author(s)
  Liu, H., Zhang, J., Liu, C. Y., Hayashi, Y., Kao
- Journal Title
  
  W. W.J Cell Mol Med
  
  Volume: 16 Pages: 1114-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591943
[Journal Article] Important role of epiregulin in inflammatory responses during corneal epithelial wound healing2012
- Author(s)
  Zhang, Y., Kobayashi, T., Hayashi, Y., Yoshioka, R., Shiraishi,A., Shirasawa, S., Higashiyama, S., Ohashi, Y
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 53 Pages: 2414-2423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591943
[Journal Article] Crosstalk between TGF-beta and MAPK signaling during corneal wound healing2011
- Author(s)
  Terai, K., Call, M. K., Liu, H., Saika, S., Liu, C. Y., Hayashi, Y., Chikama, T., Zhang, J., Terai, N., Kao, C. W., Kao
- Journal Title
  
  W. W. Invest Ophthalmol Vis Sci
  
  Volume: 52 Pages: 8208-8215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591943
[Journal Article] Monoallelic Expression of Krt12 Gene during Corneal-type Epithelium Differentiation of Limbal Stem Cells2010
- Author(s)
  Hayashi Y, Call M, Liu CY, Hayashi M, Babcock G, Ohashi Y, Kao WW
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 55 Pages: 4562-4568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591943
[Journal Article] Lumican is required for neutrophil extravasation following corneal injury and wound healing2010
- Author(s)
  Hayashi Y, Call MK, Chikama T, Liu H, Carlson EC, Sun Y, Pearlman E, Funderburgh JL, Babcock G, Liu CY, Ohashi Y, Kao W
- Journal Title
  
  Journal of Cell Science
  
  Volume: 123 Pages: 2987-2995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591943
[Journal Article] Corneal Epithelial Wound Healing Impaired in Keratinocyte-Specific HB-EGF Deficient Mice In Vivo and In Vitro2010
- Author(s)
  Yoshioka R, Shiraishi A, Kobayashi T, Morita S, Hayashi Y, Higashiyama S, and Ohashi Y.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591943
[Presentation] ケラトサイト細胞増殖周期のFucci2バイオイメージング2016
- Author(s)
  林康人
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2016-04-07
- Data Source
  KAKENHI-PROJECT-26462690
[Presentation] ケラトサイト細胞増殖周期のFucci2バイオイメージング2016
- Author(s)
  林康人
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台国際センター（宮城県、仙台市）
- Year and Date
  2016-04-07
- Data Source
  KAKENHI-PROJECT-25462756
[Presentation] 緑膿菌感染角膜のバイオイメージング2015
- Author(s)
  林康人
- Organizer
  第52回日本眼感染症学会
- Place of Presentation
  グランフロント大阪（大阪府、大阪市）
- Year and Date
  2015-07-10
- Data Source
  KAKENHI-PROJECT-25462756
[Presentation] Keratocan-IRES2-nls-Cre knock-in mouseのバイオイメージング2015
- Author(s)
  林康人
- Organizer
  第119回日本眼科学会総会
- Place of Presentation
  札幌市教育文化会館 (北海道、札幌市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-26462690
[Presentation] Keratocan-IRES2-nls-Cre knock-in mouseのバイオイメージング2015
- Author(s)
  林康人
- Organizer
  第119回日本眼科学会総会
- Place of Presentation
  札幌市教育文化会館（北海道、札幌市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25462756
[Presentation] Krt12^Cre gene Expression is required demethylation of CpG island and Exon12014
- Author(s)
  Yasuhito Hayashi, Narumi Higuchi, Naoko Takahira, Yuichi Ohashi, Winston Whei-Yang Kao
- Organizer
  ARVO 2014 Annual Meeting
- Place of Presentation
  Orlando USA
- Data Source
  KAKENHI-PROJECT-23592608
[Presentation] 角膜中央の上皮基底細胞層には胎生期由来の上皮幹細胞が残存する可能性がある2014
- Author(s)
  林康人、小林剛、白石敦、大橋裕一
- Organizer
  角膜カンファランス2014(第38回日本角膜学会総会、第30回日本角膜移植学会)
- Place of Presentation
  宜野湾
- Data Source
  KAKENHI-PROJECT-23592608
[Presentation] 角膜中央の上皮基底細胞層には胎生期由来の上皮幹細胞が残存する可能性がある2012
- Author(s)
  林康人, 小林剛, 白石敦, 大橋裕一
- Organizer
  角膜カンファランス2013
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-22591943
[Presentation] 非典型的な角膜上皮病変を呈した水痘帯状疱疹ウイルス性角膜炎の3例2012
- Author(s)
  友岡真美, 井上智之, 鈴木崇, 小林剛, 原祐子, 鄭暁東, 林康人, 山口昌彦, 白石敦, 大橋裕一
- Organizer
  角膜カンファランス2013
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-22591943
[Presentation] ソフトコンタクトレンズ用洗浄液(ミラフロー)の抗アカントアメーバ消毒効果の検討2012
- Author(s)
  小林剛, 渡部成美, 白石敦, 宇野敏彦, 大橋裕一
- Organizer
  第49回日本眼感染症学会
- Place of Presentation
  フォーサム2012横浜
- Data Source
  KAKENHI-PROJECT-22591943
[Presentation] Keratocan-IRES2-nls-Cre knock-in mouseのバイオイメージング
- Author(s)
  林　康人
- Organizer
  第119回日本眼科学会総会
- Place of Presentation
  札幌
- Year and Date
  2015-04-16 – 2015-04-19
- Data Source
  KAKENHI-PROJECT-25462756
[Presentation] Keratocan-IRES2-nls-Cre knock-in mouseのバイオイメージング
- Author(s)
  林康人
- Organizer
  第119回日本眼科学会総会
- Place of Presentation
  札幌
- Year and Date
  2015-04-16 – 2015-04-19
- Data Source
  KAKENHI-PROJECT-26462690

1. OHASHI Yuichi (00116005)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. Shiraishi Atsushi (90314963)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KOBAYASHI Takeshi (70380285)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. Takeshi Imamura (70264421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HAYASHI Yasuhito 林 康人

林 康人 ハヤシ ヤスヒト

Research Projects

Research Products

Co-Researchers

Establishment of therapeutic strategy for corneal stromal scaring treatment by applying the ZFP521 gene.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of therapeutic strategy for corneal stromal scaring treatment by applying the NF1 (von Recklinghausen disease) gene.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bone marrow mesenchymal cell transplantation for corneal stroma regenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bone Marrow Mesenchymal Cell Transplantation for thin Corneal Stroma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bio-imaging for Cornea stromal Stem Cell BiologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Krt12 gene expression mechanism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sex Hormone Effect on FGF7 Signaling andApplication for Dry EyePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

移植羊膜の細胞接着と血管新生および瘢痕化抑制効果の基礎研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The "replacement hypothesis": corneal stem cell origin epithelia are replaced by limbal stem cell origin epithelia in mouse cornea during maturation2012

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of stem cell factor and c-kit in corneal wound healing inmice2012

Author(s)

Journal Title

Data Source

[Journal Article] Bone marrow mesenchymal stem cells can differentiate and assume corneal keratocyte phenotype2012

Author(s)

Journal Title

Data Source

[Journal Article] Important role of epiregulin in inflammatory responses during corneal epithelial wound healing2012

Author(s)

Journal Title

Data Source

[Journal Article] Crosstalk between TGF-beta and MAPK signaling during corneal wound healing2011

Author(s)

Journal Title

Data Source

[Journal Article] Monoallelic Expression of Krt12 Gene during Corneal-type Epithelium Differentiation of Limbal Stem Cells2010

Author(s)

Journal Title

Data Source

[Journal Article] Lumican is required for neutrophil extravasation following corneal injury and wound healing2010

Author(s)

Journal Title

HAYASHI Yasuhito 林康人

林康人ハヤシヤスヒト