KOBAYASHI Nobuhiko 小林信彦

… Alternative Names

小林信彦コバヤシノブヒコ

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Researcher Number	70316074
Other IDs
Affiliation (based on the past Project Information) *help	2011 – 2014: 奈良県立医科大学, 医学部, 准教授 2003 – 2005: Nara Medical University, Medicine, Assistant Professor, 医学部, 講師 2000 – 2001: 奈良県立医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Dermatology / Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator モノクローナル抗体 / TFIIH / サイクロプリン / DNA修復 / (6-4)型ダイマー / 免疫蛍光染色 / シクロブタン型ダイマー / 紫外線DNA損傷 / visualization of DNA repair / monoclonal antibody … More / micropore UV irradiation / ultraviolet-induced DNA damage / xeroderma pigmentosum group D / UV-induced skin cancer / trichothiodystrophy / ELISA / 発癌 / DNA修復の可視化 / 局所紫外線照射法 / 色素性乾皮症(XP)D群 / 紫外線発癌 / トリコチオディストロフィー / 酸化的DNA損傷 / 神経症状 / 色素性乾皮症 / 紫外線感受性 / 神経芽細胞腫 / DBcAMP / 免疫組織染色 / 紫外線DAN損傷 / 共焦点レーザー顕微鏡 / 紫外線防御 / フェオメラニン / ユーメラニン … More Except Principal Investigator XPD / TFIIH / Photocarcinogenesis / Nucleotide excision repair / DNA repair / DNA damage / Ultraviolet light / Trichothiodystrophy / 光線過敏症 / ヌクレチオド除去修後 / 発癌 / ヌクレオチド除去修復 / DNA修復 / DNA損傷 / 紫外線 / トリコチオディストロフィー Less

酸化的DNA損傷サイクロプリンによる色素性乾皮症の神経症状・ＵＶＡ発癌とその予防Principal Investigator
- Principal Investigator
  
  小林信彦
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Nara Medical University
The cAMP elevation and CREB activation stimulates DNA repair capacity in skin and neuronal cells.Principal Investigator
- Principal Investigator
  
  KOBAYASHI Nobuhiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Nara Medical University
How do DNA repair-deficient trichothiodystrophy patients escape ultraviolet-light-induced skin cancers?Principal Investigator
- Principal Investigator
  
  KOBAYASHI Nobuhiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Nara Medical University
Trichothiodystrophy fibroblasts are deficient in the repair of ultraviolet-induced cyclobutane pyrimidine dimers and (6-4) photoproducts
- Principal Investigator
  
  MIYAGAWA Sachiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Nara Medical University
異なる種類のメラニン色素の紫外線誘発DNA損傷防御効果の解析Principal Investigator
- Principal Investigator
  
  小林信彦
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Dermatology
- Research Institution
  Nara Medical University

All 2015 2014 2013 2011 2005 Other

All Journal Article Presentation Book

[Book] こどものスポーツ外来　紫外線による皮膚傷害とサンプロテクション2015
- Author(s)
  小林信彦、森　俊雄
- Publisher
  全日本病院出版会
- Data Source
  KAKENHI-PROJECT-26461665
[Book] New Perspectives in Cancer Research and Therapy2005
- Author(s)
  N.Kobayashi
- Total Pages
  12
- Publisher
  Research Signpost, Kerala, India
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591114
[Book] An in vivo analysis of the dynamics of UV-induced DNA damage repair using micropore UV irradiation and specific antibodies In : New perspectives in cancer research and therapy.2005
- Author(s)
  Kobayashi N.
- Total Pages
  12
- Publisher
  Research Signpost, Kerala, India
- Data Source
  KAKENHI-PROJECT-16591114
[Book] An in vivo analysis of the dynamics of UV-induced DNA damage repair using microspore UV irradiation and specific antibodies. In: New Perspectives in Cancer Research and Therapy2005
- Author(s)
  N.Kobayashi
- Total Pages
  12
- Publisher
  Research Signpost, Kerala, India
- Data Source
  KAKENHI-PROJECT-16591114
[Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  T. Iwamoto, P.J. Brooks, T. Nishiwaki, K. Nishimura, N. Kobayashi, S. Sugiura and T. Mori.
- Journal Title
  
  Photochem. Photobiol.
  
  Volume: xx Issue: 4 Pages: 829-836
- DOI
  10.1111/php.12239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23510081, KAKENHI-PROJECT-23591626, KAKENHI-PROJECT-24651052, KAKENHI-PROJECT-24790895, KAKENHI-PROJECT-26550042
[Journal Article] Characterization of three XPG-defective patients identifies three missense mutations that impair repair and transcription.2013
- Author(s)
  A. Schafer, S. Schubert, A. Gratchev, C. Seebode, A. Apel, P. Laspe, L. Hofmann, A. Ohlenbusch, T. Mori, N. Kobayashi, A. Schurer, M.P. Schon, S. Emmert.
- Journal Title
  
  J. Invest. Dermatol.
  
  Volume: 133 Issue: 7 Pages: 1841-1849
- DOI
  10.1038/jid.2013.54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510081, KAKENHI-PROJECT-23591626
[Journal Article] An in vivo analysis of the dynamics of UV-induced DNA damage repair using micropore UV irradiation and specific antibodies.2005
- Author(s)
  Kobayashi N
- Journal Title
  
  New Perspectives in Cancer Research and Therapy (Kuriyama S, Yoshiji H eds.)(Research Signpost, Kerala, India)
  
  Pages: 421-432
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591114
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014
- Author(s)
  Iwamoto T, Brooks PJ, Kobayashi N, Sugiura S, Mori T
- Organizer
  International symposium on xeroderma pigmentosum and related diseases : disorders of DNA damage response–bench to bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-23591626
[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody.2014
- Author(s)
  Iwamoto T, Brooks PJ, Kobayashi N, Sugiura S, Mori T
- Organizer
  International symposium on xeroderma pigmentosum and related diseases: disorders of DNA damage response -bench to bedside-
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-23591626
[Presentation] 太陽紫外線による3主要ピリミジン2量体DNA損傷の誘発2011
- Author(s)
  森俊雄、吉田唯真、西村和樹、岩本顕聡、池畑広伸、小林信彦
- Organizer
  第33回日本光医学・光生物学会
- Place of Presentation
  吹田市
- Data Source
  KAKENHI-PROJECT-23591626
[Presentation] 新規モノクローナルを用いた酸化的DNA損傷サイクロプリンの定量測定と可視化
- Author(s)
  岩本顕聡、P.J. Brooks、小林信彦、杉浦重樹、森　俊雄
- Organizer
  第36回日本光医学・光生物学会
- Place of Presentation
  大阪府吹田市
- Year and Date
  2014-07-25 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-26461665

1. MORI Toshio (10115280)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. MIYAGAWA Sachiko (30094626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. IWAMOTO Takaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOBAYASHI Nobuhiko 小林 信彦

小林 信彦 コバヤシ ノブヒコ

Research Projects

Research Products

Co-Researchers

酸化的DNA損傷サイクロプリンによる色素性乾皮症の神経症状・ＵＶＡ発癌とその予防Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The cAMP elevation and CREB activation stimulates DNA repair capacity in skin and neuronal cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

How do DNA repair-deficient trichothiodystrophy patients escape ultraviolet-light-induced skin cancers?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Trichothiodystrophy fibroblasts are deficient in the repair of ultraviolet-induced cyclobutane pyrimidine dimers and (6-4) photoproducts

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

異なる種類のメラニン色素の紫外線誘発DNA損傷防御効果の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] こどものスポーツ外来 紫外線による皮膚傷害とサンプロテクション2015

Author(s)

Publisher

Data Source

[Book] New Perspectives in Cancer Research and Therapy2005

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] An in vivo analysis of the dynamics of UV-induced DNA damage repair using micropore UV irradiation and specific antibodies In : New perspectives in cancer research and therapy.2005

Author(s)

Total Pages

Publisher

Data Source

[Book] An in vivo analysis of the dynamics of UV-induced DNA damage repair using microspore UV irradiation and specific antibodies. In: New Perspectives in Cancer Research and Therapy2005

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of three XPG-defective patients identifies three missense mutations that impair repair and transcription.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An in vivo analysis of the dynamics of UV-induced DNA damage repair using micropore UV irradiation and specific antibodies.2005

Author(s)

Journal Title

Description

Data Source

[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine using an immunoassay with a novel monoclonal antibody2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Quantitative and in situ detection of oxidatively generated DNA damage 8,5’-cyclo-2’-deoxyadenosine using an immunoassay with a novel monoclonal antibody.2014

Author(s)

Organizer

Place of Presentation

Data Source

KOBAYASHI Nobuhiko 小林信彦

小林信彦コバヤシノブヒコ

[Book] こどものスポーツ外来　紫外線による皮膚傷害とサンプロテクション2015