KADOWAKI Tomoko 門脇知子

… Alternative Names

筑波知子

TSUKUBA Tomoko 筑波知子

筑波知子(門脇知子) ツクバトモコ（カドワキトモコ）

筑波知子(門脇) ツクバトモコ（カドワキ）

Less

Researcher Number	70336080
Other IDs
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(歯学系), 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 長崎大学, 医歯薬学総合研究科(歯学系), 教授 2014 – 2019: 長崎大学, 医歯薬学総合研究科(歯学系), 准教授 2017: 長崎大学, 医歯薬学総合研究科, 准教授 2012: 長崎大学, 医歯(薬)学総合研究科, 助教 2011: 長崎大学, 大学院・医歯薬学総合研究科, 助教 … More 2010: 九州大学, 歯学研究科学研究院, 助教 2010: 長崎大学, 医歯薬学総合研究科, 助教 2009: Nagasaki University, 大学院・医歯薬学総合研究科, 助教 2007 – 2008: Kyushu University, Department of Pharmacology Graduate School of Dental Science, Assistant Professor 2006: 九州大学, 歯学研究院, 助手 2005: 九州大学, 大学院歯学研究院, 助手 2001 – 2005: Kyushu Univ. Dept. of Pharmacol, Assist. Prof, 大学院・歯学研究院, 助手 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 57080:Social dentistry-related / Basic Section 57020:Oral pathobiological science-related / Pathobiological dentistry/Dental radiology / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Basic Section 57020:Oral pathobiological science-related / Pathobiological dentistry/Dental radiology / Functional basic dentistry / Basic Section 57060:Surgical dentistry-related … More / Basic Section 57030:Conservative dentistry-related / Morphological basic dentistry / Basic Section 57010:Oral biological science-related / Periodontal dentistry / Biological Sciences Less
Keywords	Principal Investigator 歯周病 / プロテアーゼ / Porphyromonas gingivalis / 炎症応答 / Rabタンパク質 / LPS / 生体応答 / ジンジパイン / 動脈硬化症 / コホート研究 … More / リスクマーカー / 小胞輸送 / 細胞外分泌 / 免疫応答 / アナフィラキシー / 炎症反応 / アレルギー反応 / マスト細胞 / ケミカルメデイエーター / 脱顆粒 / 細胞内小胞輸送 / アレルギー / 細胞内輸送 / タンパク質分解 / リソソーム / エンドソーム / molecular complex / gingipains / atherosclerosis / Protease / biological response / periodontal disease / マクロファージ / ジンジバリス菌 / 複合体 / 膜輸送・分泌 / プロテアーゼ・アドヘジン / リン酸化 / シグナル伝達 / 膜輸送 / 歯学 / 二成分制御系 / 輸送・分泌 / 細菌 / ジンジバイン / P.gingvalis / P. gingivalis / インスリン抵抗性 / 生活習慣病 / 動脈硬化 / 糖尿病 / 細菌感染 / 生体反応 … More Except Principal Investigator 歯周病 / プロテアーゼ / Porphyromonas gingivalis / 歯学 / アスパラギン酸プロテアーゼ / Rab44 / カテプシンE / Rabタンパク質 / リソソーム / ジンジパイン / ジンジバリス菌 / 薬理学 / 免疫学 / 癌 / エンドソーム・リソソーム系 / 蛋白質分解 / 生体防御 / ノックアウトマウス / カテプシンD / エンドソーム / 口腔癌細胞 / 小胞輸送 / 免疫細胞 / Periodontal disease / 歯周病治療薬 / カテプシン / 病原性因子 / 膜輸送 / 細菌 / 発現調節 / 感染症 / オートファジー / リソソーム系 / 歯周病モデル実験 / 関節リウマチモデルマウス / Rab44ノックアウトマウス / Coro1c / Rab GTPase / カテプシンK / マルチモーダルイメージング / 感染実験モデル / TRPV4 / マウス / 口腔上皮 / 歯肉 / 細胞移動 / メカノセンサー / TRPチャネル / イオンチャネル / 付着上皮 / 上皮 / 細胞内小胞輸送 / 破骨細胞 / 関節リウマチ / 細胞内輸送 / 炎症性骨破壊疾患 / 新規Rabタンパク質 / 好中球 / 免疫系細胞 / 肝細胞 / 歯周病細菌 / バイオイメージング / 生体分子 / 分泌機構 / protease / gingiva / skin / deficient mice / epithelial cells / lysosomes / endosomes / cathepsin / 上皮細胞 / Proteases / Pharmacology / Immunology / Dentistry / Tumor / Infectious disease / 免疫応答 / Drugs for periodontal disease / Specific inhibitor / Gingipains / Protease / Virulence factor / 特異的阻害剤 / host defense mechanisms / aspartic proteinases / cathepsins / gingipains / proteinases / virulence factors / periodontal disease / グラム陰性嫌気細菌 / アミノ酸・ヘム獲得 / 生存戦略 / システインプロテアーゼ / プロテアーゼ機能 / 宿主細胞傷害活性 / Lys-gingipain / Arg-gingipain / グラム陰性嫌気性細胞 / 生体防御系 / ケニア / 歯周病原細菌 / HIV感染 / ＨＩＶ / HIV / エイズ / HIVに対する抗体価 / 歯周病原細菌感染 / シグマ因子 / 二成分制御系 / 遺伝子 / 免疫 / 歯周病治療 / 炎症 / 感染 / 歯周病菌 / 血管内プラーク / 動脈硬化 / 急性冠症候群 / 虚血性心臓病 / 発現制御 / トランスレーショナルリサーチ / 蛋白質 / ノックアウト / リソーム系 / バッテン病 / 神経系 / 品質管理 / 神経変性疾患 / 蛋白質分解酵素 / エンドソーム・リソソーム / オートオファジー / タンパク質分解 Less

小胞輸送系分子を基軸とする関節リウマチモデルマウスの病態解明
- Principal Investigator
  
  山口優
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
新規Rabタンパク質機能に着目した歯周疾患発症と病態形成の解析
- Principal Investigator
  
  近藤好夫
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nagasaki University
Imaging analysis of the dynamics of lysosomal membranes involved in the acidic environment of oral cancer cells
- Principal Investigator
  
  角忠輝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
コホートを用いた歯周病と全身炎症を繋ぐ分子基盤の解明と病態制御への応用Principal Investigator
- Principal Investigator
  
  門脇知子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Nagasaki University
歯周病発症における新規小胞輸送因子の分子機構の解析
- Principal Investigator
  
  近藤好夫
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
Multimodal imaging analysis of oral cancer cells focused on lysosomes
- Principal Investigator
  
  角忠輝
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nagasaki University
Functional and pathological analyses of inflammatory bone destruction disease by a novel Rab protein
- Principal Investigator
  
  Tsukuba Takayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
Involvement of mechanosensors in periodontal disease
- Principal Investigator
  
  Kido Mizuho
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Saga University
Function of a novel Rab protein in neutrophils and its role in periodontal disease
- Principal Investigator
  
  Yukitake Hideharu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nagasaki University
Regulatory mechanism of mast cell degranulation by the novel Rab proteinPrincipal Investigator
- Principal Investigator
  
  Kadowaki Tomoko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nagasaki University
Discovery of a novel gene regulating membrane trafficking of immune cells and elucidation of its pathology
- Principal Investigator
  
  TSUKUBA Takayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Elucidation of cascade regulation by two different control systems of the type IX secretion system
- Principal Investigator
  
  NAKAYAMA Koji
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Analyses using bioimaging of invasion and colonization mechanisms by periodontal bacteria in the liver
- Principal Investigator
  
  TSUKUBA Takayuki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Elucidation of chronic inflammation exacerbation mechanism due to breakdown of endo-lysosomal proteolysisPrincipal Investigator
- Principal Investigator
  
  KADOWAKI Tomoko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagasaki University
Relationship between periodontal infection and HIV infection in Kenya using simultaneous microsphere-based multiplex assays
- Principal Investigator
  
  NAKAYAMA Koji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Nagasaki University
歯周病細菌における病原性因子分泌調節メカニズムの解明Principal Investigator
- Principal Investigator
  
  筑波知子 (門脇知子)
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Dual regulation of secretion system of periodontal virulence factors by novel two-component system and ECF sigma factor
- Principal Investigator
  
  NAKAYAMA Koji
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nagasaki University
Investigation of the secretion system of pathogenic proteinases in Porphyromonas gingivalis and study of the way to control the systemPrincipal Investigator
- Principal Investigator
  
  TSUKUBA Tomoko (KADOWAKI Tomoko)
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Development of the treatment for acute coronary syndrome by dental bacteria elimination
- Principal Investigator
  
  SASAKI Ken-Ichiro, YOSHIO Katsuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Kurume University
Protease-mediated regulation of host immune system and application as therapeutic targets
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Experimental analysis of the correlation between periodontal disease and insulin resistancePrincipal Investigator
- Principal Investigator
  
  TSUKUBA Tomoko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Function of endo-lysosomal proteinases in epithelial cells
- Principal Investigator
  
  TSUKUBA Takayuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
  Kyushu University
生体防御系におけるプロテアーゼの機能解析
- Principal Investigator
  
  山本健二
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Examination of biological response to Porphyromonas gingivalis infection.Principal Investigator
- Principal Investigator
  
  TSUKUBA Tomoko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
Molecular basis of host immune responses to periodontal disease
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
歯周病における免疫制御系プロテアーゼの機能解析
- Principal Investigator
  
  山本健二
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
歯周病原性プロテアーゼに対する生体反応と心循環系傷害機序に関する研究Principal Investigator
- Principal Investigator
  
  筑波知子 (門脇知子)
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
ESTABLISHMENT OF A CLINICAL TREATMENT SYSTEM FOR PERIODONTAL DISEASE
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY
神経系におけるオートファジー・リソソームシステム
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
MOLECULAR BASIS OF PROTEINASE FUNCTION IN PROGRESSION OF PERIODONTAL DISEASES
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYUSHU UNIVERSITY

[Book] 現代歯科薬理学第7版2024
- Author(s)
  鈴木邦明、戸苅彰史、青木和広、兼松隆、筑波隆幸、八田光世
- Total Pages
  416
- Publisher
  医歯薬出版
- ISBN
  9784263456774
- Data Source
  KAKENHI-PROJECT-21K10047
[Book] 現代歯科薬理学第6版2018
- Author(s)
  大谷啓一　監著／鈴木邦明・戸苅彰史・青木和広・兼松隆・筑波隆幸　編
- Total Pages
  448
- Publisher
  医歯薬出版
- ISBN
  9784263458112
- Data Source
  KAKENHI-PROJECT-16K15790
[Book] 現代歯科薬理学第6版2018
- Author(s)
  大谷啓一　監著／鈴木邦明・戸苅彰史・青木和広・兼松隆・筑波隆幸　編
- Total Pages
  448
- Publisher
  医歯薬出版
- ISBN
  9784263458112
- Data Source
  KAKENHI-PROJECT-17H04379
[Book] 日本薬理学会誌 1222003
- Author(s)
  門脇知子
- Publisher
  日本薬理学会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Book] 日本薬理学会誌 1222003
- Author(s)
  筑波隆幸
- Publisher
  日本薬理学会
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Book] 蛋白質核酸酵素第46巻2001
- Author(s)
  筑波隆幸
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Transposon mutagenesis and genome sequencing identify two novel, tandem genes involved in the colony spreading of Flavobacterium collinsii, isolated from an ayu fish, Plecoglossus altivelis2023
- Author(s)
  Kondo Yoshio、Ohara Kenichi、Fujii Ryoji、Nakai Yudai、Sato Chikara、Naito Mariko、Tsukuba Takayuki、Kadowaki Tomoko、Sato Keiko
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 13 Pages: 01-16
- DOI
  10.3389/fcimb.2023.1095919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-22K09942, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09507, KAKENHI-PROJECT-20K10270
[Journal Article] Rab44 deficiency accelerates recovery from muscle damage by regulating mTORC1 signaling and transport of fusogenic regulators2023
- Author(s)
  Oyakawa Shun、Yamaguchi Yu、Kadowaki Tomoko、Sakai Eiko、Noguromi Mayuko、Tanimoto Ayuko、Ono Yusuke、Murata Hiroshi、Tsukuba Takayuki
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 238 Issue: 10 Pages: 2253-2266
- DOI
  10.1002/jcp.31082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09507, KAKENHI-PROJECT-23K27808
[Journal Article] Abr, a Rho-regulating protein, modulates osteoclastogenesis by enhancing lamellipodia formation by interacting with poly(ADP-ribose) glycohydrolase2023
- Author(s)
  Farhana Fatima、Sakai Eiko、Koyanagi Yu、Yamaguchi Yu、Alam Mohammad Ibtehaz、Okamoto Kuniaki、Tsukuba Takayuki
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 9 Pages: 7557-7569
- DOI
  10.1007/s11033-023-08690-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09152, KAKENHI-PROJECT-23K09507, KAKENHI-PROJECT-20K09474
[Journal Article] Rab44 Deficiency Induces Impaired Immune Responses to Nickel Allergy2023
- Author(s)
  Noguromi Mayuko、Yamaguchi Yu、Sato Keiko、Oyakawa Shun、Okamoto Kuniaki、Murata Hiroshi、Tsukuba Takayuki、Kadowaki Tomoko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 2 Pages: 994-994
- DOI
  10.3390/ijms24020994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-22K09942, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09507
[Journal Article] Rab44 negatively regulates myoblast differentiation by controlling fusogenic protein transport and mTORC1 signaling2023
- Author(s)
  Tanimoto Ayuko、Yamaguchi Yu、Kadowaki Tomoko、Sakai Eiko、Oyakawa Shun、Ono Yusuke、Yoshida Noriaki、Tsukuba Takayuki
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: 124 Issue: 10 Pages: 1486-1502
- DOI
  10.1002/jcb.30457
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-23K09440, KAKENHI-PROJECT-23K09507, KAKENHI-PROJECT-20K10209, KAKENHI-PROJECT-23K27808
[Journal Article] Coronin1C is a GDP-specific Rab44 effector that controls osteoclast formation by regulating cell motility in macrophages.2022
- Author(s)
  Yu Yamaguchi, Tomoko Kadowaki, Nozomi Aibara, Kaname Ohyama, Kuniaki Okamoto, Eiko Sakai and Takayuki Tsukuba
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 23 Issue: 12 Pages: 6619-6619
- DOI
  10.3390/ijms23126619
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-22K17004, KAKENHI-PROJECT-20H03860
[Journal Article] Rab34 plays a critical role as a bidirectional regulator of osteoclastogenesis2022
- Author(s)
  Feng Yunxia、Tran Manh Tien、Lu Yanyin、Htike Kaung、Okusha Yuka、Sogawa Chiharu、Eguchi Takanori、Kadowaki Tomoko、Sakai Eiko、Tsukuba Takayuki、Okamoto Kuniaki
- Journal Title
  
  Cell Biochemistry and Function
  
  Volume: 40 Issue: 3 Pages: 263-277
- DOI
  10.1002/cbf.3691
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20K09904, KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-20H03860
[Journal Article] HSP90 drives the Rab11a-mediated vesicular transport of the cell surface receptors in osteoclasts2022
- Author(s)
  Tran MT, Okusha Y, Feng Y, Sogawa C, Eguchi T, Kadowaki T, Sakai E, Tsukuba T, Okamoto K
- Journal Title
  
  Cell Biochem Funct
  
  Volume: 40（8） Issue: 8 Pages: 838-855
- DOI
  10.1002/cbf.3745
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09904, KAKENHI-PROJECT-21K09844, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-20H03860
[Journal Article] A novel role of HSP90 in regulating osteoclastogenesis by abrogating Rab11b-driven transport2021
- Author(s)
  Tran Manh Tien、Okusha Yuka、Feng Yunxia、Sogawa Chiharu、Eguchi Takanori、Kadowaki Tomoko、Sakai Eiko、Tsukuba Takayuki、Okamoto Kuniaki
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 1868 Issue: 10 Pages: 119096-119096
- DOI
  10.1016/j.bbamcr.2021.119096
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-20K09904, KAKENHI-PROJECT-21K10047
[Journal Article] Rab44 isoforms similarly promote lysosomal exocytosis, but exhibit differential localization in mast cells.2021
- Author(s)
  Kadowaki T, Yamaguchi Y, Ogawa K, Tokuhisa M, Okamoto K, Tsukuba T.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 11 Issue: 4 Pages: 1165-1185
- DOI
  10.1002/2211-5463.13133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-21K10047
[Journal Article] Liquid-phase ASEM imaging of cellular and structural details in cartilage and bone formed during endochondral ossification: Keap1-deficient osteomalacia2021
- Author(s)
  Sakai E, Sato M, Memtily N, Tsukuba T, Sato C.
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Issue: 1 Pages: 5722-5722
- DOI
  10.1038/s41598-021-84202-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-19K10055, KAKENHI-PROJECT-21K10047
[Journal Article] Large Rab GTPases: Novel Membrane Trafficking Regulators with a Calcium Sensor and Functional Domains2021
- Author(s)
  Tsukuba Takayuki、Yamaguchi Yu、Kadowaki Tomoko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 14 Pages: 7691-7691
- DOI
  10.3390/ijms22147691
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-21K10047
[Journal Article] Receptor for advanced glycation end products up‐regulation in cerebral endothelial cells mediates cerebrovascular‐related amyloid β accumulation after Porphyromonas gingivalis infection2021
- Author(s)
  Zeng Fan、Liu Yicong、Huang Wanyi、Qing Hong、Kadowaki Tomoko、Kashiwazaki Haruhiko、Ni Junjun、Wu Zhou
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 158 Issue: 3 Pages: 724-736
- DOI
  10.1111/jnc.15096
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09536
[Journal Article] The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis2021
- Author(s)
  Mae Megumi、Alam Mohammad Ibtehaz、Yamashita Yasunori、Ozaki Yukio、Higuchi Kanako、Ziauddin S. M.、Montenegro Raudales Jorge Luis、Sakai Eiko、Tsukuba Takayuki、Yoshimura Atsutoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 22 Pages: 12434-12434
- DOI
  10.3390/ijms222212434
- NAID
  120007186852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860, KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-20K09942, KAKENHI-PROJECT-21K10047, KAKENHI-PROJECT-18K17072, KAKENHI-PROJECT-20K18540
[Journal Article] Porphyromonas Gingivalis Infection Induces Synaptic Failure via Increased IL-1β Production in Leptomeningeal Cells2021
- Author(s)
  Huang Wanyi、Zeng Fan、Gu Yebo、Jiang Muzhou、Zhang Xinwen、Yan Xu、Kadowaki Tomoko、Mizutani Shinsuke、Kashiwazaki Haruhiko、Ni Junjun、Wu Zhou
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 83 Issue: 2 Pages: 665-681
- DOI
  10.3233/jad-210031
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09536
[Journal Article] Dimethyl fumarate prevents osteoclastogenesis by decreasing NFATc1 expression, inhibiting of erk and p38 MAPK phosphorylation, and suppressing of HMGB1 release2020
- Author(s)
  Nishioku T, Kawamoto M, Okizono R, Sakai E, Okamoto K, Tsukuba T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 530 Issue: 2 Pages: 455-461
- DOI
  10.1016/j.bbrc.2020.05.088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-20H03860
[Journal Article] Rab11A Functions as a Negative Regulator of Osteoclastogenesis through Dictating Lysosome-Induced Proteolysis of c-fms and RANK Surface Receptors.2020
- Author(s)
  Okusha Y, Tran MT, Itagaki M, Sogawa C, Eguchi T, Okui T, Kadowaki T, Sakai E, Tsukuba T, Okamoto K.
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 11 Pages: 2384-2384
- DOI
  10.3390/cells9112384
- NAID
  120006941059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-20K09904, KAKENHI-PROJECT-20H03860
[Journal Article] (−)-Epigallocatechin-3-gallate inhibits RANKL-induced osteoclastogenesis via downregulation of NFATc1 and suppression of HO-1–HMGB1–RAGE pathway2020
- Author(s)
  Nishioku T, Kubo T, Kamada T, Okamoto K, Tsukuba T, Uto T, Shoyama Y.
- Journal Title
  
  Biomed. Res.
  
  Volume: 41 Issue: 6 Pages: 269-277
- DOI
  10.2220/biomedres.41.269
- NAID
  130007948845
- ISSN
  0388-6107, 1880-313X
- Year and Date
  2020-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860
[Journal Article] . The Inhibitory Role of Rab11b in Osteoclastogenesis through Triggering Lysosome-Induced Degradation of c-Fms and RANK Surface Receptors.2020
- Author(s)
  Tran MT, Okusha Y, Feng Y, Morimatsu M, Wei P, Sogawa C, Eguchi T, Kadowaki T, Sakai E, Okamura H, Naruse K, Tsukuba T, Okamoto K
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 24 Pages: 9352-9352
- DOI
  10.3390/ijms21249352
- NAID
  120006952291
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20K09474, KAKENHI-PROJECT-20K09904, KAKENHI-PROJECT-20K21896, KAKENHI-PROJECT-19H04051, KAKENHI-PROJECT-20H03860
[Journal Article] Role of the EF-hand and coiled-coil domains of human Rab44 in localisation and organelle formation.2020
- Author(s)
  Ogawa K, Kadowaki T, Tokuhisa M, Yamaguchi Y, Umeda M, Tsukuba T.
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Issue: 1 Pages: 19149-19149
- DOI
  10.1038/s41598-020-75897-7
- NAID
  120006988463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860
[Journal Article] The large GTPase Rab44 regulates granule exocytosis in mast cells and IgE-mediated anaphylaxis.2020
- Author(s)
  Kadowaki T, Yamaguchi Y, Kido MA, Abe T, Ogawa K, Tokuhisa M, Gao W, Okamoto K, Kiyonari H, Tsukuba T.
- Journal Title
  
  Cell Mol Immunol.
  
  Volume: 17 Issue: 12 Pages: 1287-1289
- DOI
  10.1038/s41423-020-0413-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-20H03860
[Journal Article] Expression and localisation of Rab44 in immune-related cells change during cell differentiation and stimulation.2020
- Author(s)
  Tokuhisa M., Kadowaki T., Ogawa K., Yamaguchi Y., Kido MA., Gao W., Umeda M., Tsukuba T.
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Issue: 1 Pages: 10728-10728
- DOI
  10.1038/s41598-020-67638-7
- NAID
  120006988132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09536, KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-20H03860
[Journal Article] KBTBD11, a novel BTB-Kelch protein, is a negative regulator of osteoclastogenesis through controlling Cullin3-mediated ubiquitination of NFATc1.2019
- Author(s)
  Narahara S, Sakai E, Kadowaki T, Yamaguchi Y, Narahara H, Okamoto K, Asahina I, Tsukuba T.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 3523-3523
- DOI
  10.1038/s41598-019-40240-2
- NAID
  120006987780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11863
[Journal Article] Calcium phosphate mineralization in bone tissues directly observed in aqueous liquid by atmospheric SEM (ASEM) without staining: microfluidics crystallization chamber and immuno-EM.2019
- Author(s)
  Sato C, Yamazaki D, Sato M, Takeshima H, Memtily N, Hatano Y, Tsukuba T, Sakai E.
- Journal Title
  
  Sci Rep.
  
  Volume: 9(1) Issue: 1 Pages: 7352-7352
- DOI
  10.1038/s41598-019-43608-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10092, KAKENHI-PROJECT-19K10112, KAKENHI-PROJECT-17H04379
[Journal Article] Inhibition of gingipains prevents Porphyromonas gingivalis-induced preterm birth and fetal death in pregnant mice.2018
- Author(s)
  Takii R, Kadowaki T, Tsukuba T, Yamamoto K.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 824 Pages: 48-56
- DOI
  10.1016/j.ejphar.2018.01.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04706, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K08625
[Journal Article] Rutaecarpine attenuates osteoclastogenesis by impairing M-CSF and RANKL-stimulated signaling pathways.2018
- Author(s)
  Fukuma Y, Sakai E, Komaki S, Nishishita K, Okamoto K, Tsukuba T.
- Journal Title
  
  Clin Exp Pharmacol Physiol.
  
  Volume: 印刷中 Issue: 8 Pages: 863-865
- DOI
  10.1111/1440-1681.12941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-16K11480
[Journal Article] <b>Dihydroartemisinin represses osteoclastogenesis of bone marrow macrophages through reduced NFATc1 expression and impaired phosphorylation of </b><b>IκBα </b>2018
- Author(s)
  Komaki S, Sakai E, Fukuma Y, Nishishita K, Okamoto K, Tsukuba T.
- Journal Title
  
  Biomed. Res.
  
  Volume: 39 Issue: 4 Pages: 169-177
- DOI
  10.2220/biomedres.39.169
- NAID
  130007432891
- ISSN
  0388-6107, 1880-313X
- Year and Date
  2018-08-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11480, KAKENHI-PROJECT-16K11863
[Journal Article] Rab44, a novel large Rab GTPase, negatively regulates osteoclast differentiation by modulating intracellular calcium levels followed by NFATc1 activation.2018
- Author(s)
  Yu Yamaguchi, Eiko Sakai, Kuniaki Okamoto, Hiroshi Kajiya, Koji Okabe, Mariko Naito, Tomoko Kadowaki and Tsukuba T
- Journal Title
  
  Cell Mol Life Sci.
  
  Volume: 75 Issue: 1 Pages: 33-48
- DOI
  10.1007/s00018-017-2607-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19769, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-16H05509, KAKENHI-PROJECT-16J03008, KAKENHI-PROJECT-15K11062, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-15K15689, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-17H04379
[Journal Article] Transcription factor EB influences invasion and migration in oral squamous cell carcinomas.2018
- Author(s)
  Sakamoto H, Yamashita K, Okamoto K, Kadowaki T, Sakai E, Umeda M, Tsukuba T.
- Journal Title
  
  Oral Dis.
  
  Volume: 印刷中 Issue: 5 Pages: 741-748
- DOI
  10.1111/odi.12826
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-17H04379
[Journal Article] Actin binding LIM 1 (abLIM1) negatively controls osteoclastogenesis by regulating cell migration and fusion2018
- Author(s)
  Narahara H, Sakai E, Yamaguchi Y, Narahara S, Iwatake M, Okamoto K, Yoshida N, Tsukuba T
- Journal Title
  
  J Cell Physiol
  
  Volume: 234 Issue: 1 Pages: 486-499
- DOI
  10.1002/jcp.26605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15840, KAKENHI-PROJECT-17H04379
[Journal Article] New functions of lysosomes in bone cells2017
- Author(s)
  Tsukuba T, Sakai E, Nishishita K, Kadowaki T, Okamoto K
- Journal Title
  
  J. Oral Biosci.
  
  Volume: 59 Pages: 92-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K11079
[Journal Article] The Rho-specific guanine nucleotide exchange factor Plekhg5 modulates cell polarity, adhesion, migration, and podosome organization in macrophages and osteoclasts.2017
- Author(s)
  Iwatake M, Nishishita K, Okamoto K, Tsukuba T.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 359(2) Issue: 2 Pages: 415-430
- DOI
  10.1016/j.yexcr.2017.08.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-17K11847
[Journal Article] Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice2017
- Author(s)
  Liu Yicong、Wu Zhou、Nakanishi Yurika、Ni Junjun、Hayashi Yoshinori、Takayama Fumiko、Zhou Yanmin、Kadawaki Tomoko、Nakanishi Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-017-12173-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11478, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-18K19650
[Journal Article] Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic-1 during osteoclastogenesis2017
- Author(s)
  Sakai E., Morita M., Ohuchi M., Kido MA., Fukuma Y., Nishishita K., Okamoto K., Itoh K., Yamamoto M, and Tsukuba T
- Journal Title
  
  FASEB Journal
  
  Volume: 31 Issue: 9 Pages: 4011-4022
- DOI
  10.1096/fj.201700177r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11480, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-25293064
[Journal Article] Cathepsin K modulates invasion, migration and adhesion of oral squamous cell carcinomas in vitro.2017
- Author(s)
  Yamashita K, Iwatake M, Okamoto K, Yamada SI, Umeda M, Tsukuba T.
- Journal Title
  
  Oral Dis
  
  Volume: 23 Issue: 4 Pages: 518-525
- DOI
  10.1111/odi.12643
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-16H00687, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11510
[Journal Article] The dental resin monomers HEMA and TEGDMA have inhibitory effects on osteoclast differentiation with low cytotoxicity2017
- Author(s)
  Inamitsu H, Okamoto K, Sakai E, Murata H, Tsukuba T
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 印刷中 Issue: 7 Pages: 817-824
- DOI
  10.1002/jat.3429
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293413, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-17H04393, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790
[Journal Article] Rab27A regulates transport of cell surface receptors modulating multinucleation and lysosome-related organelles in osteoclasts.2016
- Author(s)
  Shimada-Sugawara M, Sakai E, Okamoto K, Fukuda M, Izumi T, Yoshida N, Tsukuba T
- Journal Title
  
  Sci Rep
  
  Volume: 印刷中 Issue: 6 Pages: 1321-1333
- DOI
  10.1002/jcp.25235
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05050, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-16H07077, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-16K15790
[Journal Article] Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)2016
- Author(s)
  Klionsky DJ., Abdelmohsen K., Abe A., Abedin MJ.,Inomata M., et al.
- Journal Title
  
  Autophagy
  
  Volume: 12(1) Issue: 1 Pages: 1-222
- DOI
  10.1080/15548627.2015.1100356
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11094, KAKENHI-PROJECT-15K14681, KAKENHI-PROJECT-15K14951, KAKENHI-PUBLICLY-15H01239, KAKENHI-PUBLICLY-15H01380, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007, KAKENHI-PLANNED-26110003, KAKENHI-PUBLICLY-26111501, KAKENHI-PUBLICLY-26111503, KAKENHI-PUBLICLY-26111505, KAKENHI-PUBLICLY-26111514, KAKENHI-PUBLICLY-26111521, KAKENHI-PUBLICLY-26117727, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-15H06095, KAKENHI-PROJECT-25460072, KAKENHI-PROJECT-25461364, KAKENHI-PROJECT-25462920, KAKENHI-PROJECT-26670446, KAKENHI-PROJECT-26670906, KAKENHI-PROJECT-25850198, KAKENHI-PROJECT-25290014, KAKENHI-PROJECT-25291040, KAKENHI-PROJECT-25291042, KAKENHI-PROJECT-25293383, KAKENHI-PROJECT-26290018, KAKENHI-PROJECT-26291039, KAKENHI-PROJECT-26292032, KAKENHI-PROJECT-26293179, KAKENHI-PROJECT-26713005, KAKENHI-PUBLICLY-15H01545, KAKENHI-PUBLICLY-15H01572, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111003, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-26253094, KAKENHI-PROJECT-16H05291, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-26293070, KAKENHI-PROJECT-26293207, KAKENHI-PROJECT-25711005, KAKENHI-PROJECT-26430050, KAKENHI-PROJECT-15K06791, KAKENHI-PROJECT-15K08376, KAKENHI-PROJECT-15K10908, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-15K12749, KAKENHI-PROJECT-16K15194, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-16K15853, KAKENHI-PROJECT-15K16486, KAKENHI-PROJECT-16H05107, KAKENHI-PROJECT-20H03453
[Journal Article] Lipid droplets affect elimination of Porphyromonas gingivalis in HepG2 cells by altering the autophagy-lysosome system2016
- Author(s)
  Zaitsu Y, Iwatake M, Sato K, Tsukuba T
- Journal Title
  
  Microbes Infect.
  
  Volume: 18 Issue: 9 Pages: 565-571
- DOI
  10.1016/j.micinf.2016.05.004
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-16K15790
[Journal Article] Sanguiin H-6, a constituent of Rubus parvifolius L., inhibits receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis and bone resorption in vitro and inhibits tumor necrosis factor-α-induced osteoclastogenesis in vivo.2016
- Author(s)
  Sakai E, Aoki Y, Yoshimatsu M, Nishishita K, Iwatake M, Fukuma Y, Okamoto K, Tanaka T, Tsukuba T
- Journal Title
  
  Phytomedicine
  
  Volume: 23 Issue: 8 Pages: 828-837
- DOI
  10.1016/j.phymed.2016.04.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-16K15790
[Journal Article] A two-component system regulates gene expression of the type IX secretion component proteins via an ECF sigma factor2016
- Author(s)
  門脇知子, 雪竹英治, 内藤真理子, 佐藤啓子, 菊池有一郎, 近藤好夫, 庄子幹郎, 中山浩次
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 23288-23288
- DOI
  10.1038/srep23288
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26463171, KAKENHI-PLANNED-24117006, KAKENHI-PROJECT-25462863, KAKENHI-PROJECT-25462866, KAKENHI-PROJECT-25462925, KAKENHI-PROJECT-25293375, KAKENHI-PROJECT-15K11079, KAKENHI-PROJECT-15K20598, KAKENHI-PROJECT-16K15776
[Journal Article] Rab27A Regulates Transport of Cell Surface Receptors Modulating Multinucleation and Lysosome Related Organellas in osteoclasts2015
- Author(s)
  Megumi Shimada-Sugawara,Eiko Sakai,Kuniaki Okamoto,Mitsunori Fukuda,Tetsuro Izumi,Noriaki Yoshida,Takayuki Tsukuba
- Journal Title
  
  SCIENTIFIC REPORTS
  
  Volume: 5 Issue: 1 Pages: 9620-9620
- DOI
  10.1038/srep09620
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J10718, KAKENHI-PROJECT-24390068, KAKENHI-PROJECT-26670133, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-25462920, KAKENHI-PROJECT-26670906, KAKENHI-PROJECT-25293383, KAKENHI-PROJECT-15K11079
[Journal Article] Analysis of a Lys-specific serine endopeptidase secreted via the type IX secretion system in Porphyromonas gingivalis.2014
- Author(s)
  Nonaka M, Shoji M, Kadowaki T, Sato K, Yukitake H, Naito M, Nakayama K
- Journal Title
  
  FEMS Microbiology Letters
  
  Volume: in press Issue: 1 Pages: 60-68
- DOI
  10.1111/1574-6968.12426
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24406034, KAKENHI-PROJECT-25293375, KAKENHI-PROJECT-25462863, KAKENHI-PROJECT-25462866, KAKENHI-PROJECT-25462925
[Journal Article] Suppression of RANKL-dependent heme oxygenase-1 is required for high mobility group box 1 release and osteoclastogenesis2012
- Author(s)
  Sakai E, Shimada-Sugawara M, Nishishita K, Fukuma Y, Naito M, Okamoto K, Nakayama K, Tsukuba T
- Journal Title
  
  J Cell Biochem
  
  Volume: 113 Pages: 486-498
- Data Source
  KAKENHI-PROJECT-22659332
[Journal Article] Por secretion system-dependent secretion and glycosylation of Porphyromonas gingivalis hemin-binding protein 352011
- Author(s)
  Shoji M, Sato K, Yukitake H, Kondo Y, Narita Y, Kadowaki T, Naito M, and Nakayama K.
- Journal Title
  
  PLoS One
  
  Volume: 6
- NAID
  120006985054
- Data Source
  KAKENHI-PROJECT-22659332
[Journal Article] Por secretion system-dependent secretion and glycosylation of Porphyromonas gingivalis hemin-binding protein 352011
- Author(s)
  Shoji M, Sato K, Yukitake H, Kondo Y, Narita Y, Kadowaki T, Naito M, and Nakayama K
- Journal Title
  
  PLoS One
  
  Volume: 6
- NAID
  120006985054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592364
[Journal Article] Por secretion system-dependent secretion and glycosylation of Porphyromonas gingivalis hemin-binding protein 352011
- Author(s)
  Shoji M, Sato K, Yukitake H, Kondo Y, Narita Y, Kadowaki T, Naito M, Nakayama K
- Journal Title
  
  PLoS One
  
  Volume: 6 Issue: 6 Pages: 21372-21372
- DOI
  10.1371/journal.pone.0021372
- NAID
  120006985054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592364, KAKENHI-PROJECT-22890142, KAKENHI-PROJECT-23792110
[Journal Article] Impaired chemotaxis and cell adhesion due to decrease in wide range of cell surface receptors in cathepsin E-deficient macrophages2009
- Author(s)
  Tsukuba T, et al.
- Journal Title
  
  Journal of Biochemistry 145(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Impaired chemotaxis and cell adhesion due to decrease in wide range of cell surface receptors in cathepsin E-deficient macrophages.2009
- Author(s)
  Tsukuba T, Yanagawa M, Okamoto K, Okamoto Y, Yasuda Y, Nakayama KI, Kadowaki T, Yamamoto K.
- Journal Title
  
  J. Biochem. 145(5)
  
  Pages: 565-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Impaired chemotaxis and cell adhesion due to decrease in several cell-surface receptors in cathepsin E-deficient macrophages2009
- Author(s)
  Tsukuba T, Yanagawa M, Okamoto K, Okamoto Y, Yasuda Y, Nakayama KI, Kadowaki T, Yamamoto K
- Journal Title
  
  J Biochem
  
  Volume: 145(5) Pages: 565-573
- Data Source
  KAKENHI-PROJECT-21592364
[Journal Article] Development of systemin in vitro evolution and its application to generation of peptide aptamer-based inhibitors of cathepsin E.2009
- Author(s)
  Kitamura K, Yoshida C, Kinoshita Y, Kadowaki T, Takahashi Y, Tayama T, Kawakubo T, Naimuddin M, Salimulla M, Nemoto N, Hanada K, Husimi Y, Yamamoto K, Nishigaki K.
- Journal Title
  
  J. Mol. Biol. 387
  
  Pages: 1186-1198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Impaired chemotaxis and cell adhesion due to decrease in wide range of cell surface receptors in cathepsin E-deficient macrophages.2009
- Author(s)
  Tsukuba, T,, et al.
- Journal Title
  
  J. Biochem. 145
  
  Pages: 565-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mice2008
- Author(s)
  Shigematsu, N, Fukuda, T, Yamamoto, T, Nishioku, T, Yamaguchi, T, Himeno, M, Nakayama, KI, Tsukuba, T, Kadowaki, T, Okamoto, K, Higuchi, S, Yamamoto, K
- Journal Title
  
  J Neurochem (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mouse2008
- Author(s)
  Shigematsu N, Fukuda T, Yamamoto T, Nishioku T, Yamaguchi T, Himeno M, Nakayama KI, Tsukuba T, Kadowaki T, Okamoto K, Higuchi S, Yamamoto K.
- Journal Title
  
  J. Neurochem 105
  
  Pages: 1394-1404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Dentin phosphophoryn promotes cellular migration of human dental pulp cells2008
- Author(s)
  Yasuda Y, Izumikawa M, Okamoto K, Tsukuba T, Saito T
- Journal Title
  
  J Endodont 34
  
  Pages: 575-578
- NAID
  120006981302
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell Surface2008
- Author(s)
  Kawakubo T, Okamoto K, Iwata J, Shin M, Okamoto Y, Yasukochi A, Nakayama KI, Kadowaki T, Tsukuba T, Yamamoto K.
- Journal Title
  
  Cancer Res 67
  
  Pages: 10869-10878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Gene expression profiling of mammary elands of cathepsin E-deficient mice compared with wild-type littermates2008
- Author(s)
  Kawakubo, T, Yasukochi, A, Tsukuba, T, Kadowaki, T, Yamamoto, K
- Journal Title
  
  Biochimie 90
  
  Pages: 396-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mice2008
- Author(s)
  Shigematsu N, Fukuda T, Yamamoto T, Nishioku T, Yamaguchi T, Himeno M, Nakayama. KI, Tsukuba T, Kadowaki T, Okamoto K, Higuchi S, Yamamoto K.
- Journal Title
  
  J Neurochem. 105
  
  Pages: 1394-1404
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Determination of active site of lysine-specific cysteine proteinase(Lys-gingipain)by use of a Porphyromonas gingivalis plasmid system2008
- Author(s)
  Ishida Y, Hu J, Sakai E, Kadowaki T, Yamamoto K, Tsukuba T, Kato Y, Nakayama K, Okamoto K.
- Journal Title
  
  Arch Oral Biol. 53
  
  Pages: 538-544
- NAID
  120006984583
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Determination of active site of Lysine-specific cysteine proteinase (Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system.2008
- Author(s)
  Ishida Y., Hu J.P., Sakai E., Kadowaki T., Yamamoto K., Tsukuba T., Nakayama K., Okamoto K.
- Journal Title
  
  Arch. Oral Biol. 53(6)
  
  Pages: 538-544
- NAID
  120006984583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Gene expression of profiling of mammary glands of cathepsin E-deficient mice compared with wild-type littermates.2008
- Author(s)
  Kawakubo T., Yasukochi A., Tsukuba T., Kadowaki T., Yamamoto K.
- Journal Title
  
  Biochimie 90
  
  Pages: 396-404
- NAID
  120006900027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Determination of active site of Lysine-specific cysteine proteinase (Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system2008
- Author(s)
  Ishida Y, Hu JP, Sakai E, Kadowaki T, Yamamoto K, Tsukuba T, Nakayama K, Okamoto K
- Journal Title
  
  Arch. Oral Biol 53
  
  Pages: 538-544
- NAID
  120006984583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Association of cathepsin E deficiency with the increased territorial aggressive response of mouse2008
- Author(s)
  Shigematsu N., Fukuda T., Yamamoto T., Nishioku T., Yamaguchi T., Himeno M., Nakayama K.I., Tsukuba T., Kadowaki T., Okamoto K., Higuchi S., Yamamoto K.
- Journal Title
  
  J. Neurochem. 105
  
  Pages: 1394-1404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Determination of active site of lysine-specific cysteine proteinase(Lys-gingipain) by use of a Porphyromonas gingivalis plasmid system2008
- Author(s)
  Y, Hu, J, Sakai, E, Kadowaki, T, Yamamoto, K, Tsukuba, T, Kato, Y, Nakayama, K, Okamoto, K
- Journal Title
  
  Arch Oral Biol (in press)
- NAID
  120006984583
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Dentin phosphophoryn promotes cellular migration of human dental pulp cells2008
- Author(s)
  Ishida, Yasuda, Y, Izumikawa, M, Okamoto, K, Tsukuba, T, Saito, T
- Journal Title
  
  J Endodont (in press)
- NAID
  120006981302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] The effect of mineral trioxide aggregate on the mineralization ability of rat dental pulp cells: an in vitro study2008
- Author(s)
  Yasuda Y, Ogawa M, Arakawa T, Kadowaki T, Saito T.
- Journal Title
  
  J.Endodontics 34
  
  Pages: 1057-1060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways2008
- Author(s)
  Hu, JP, Nishishita, K, Sakai, E, Yoshida, H, Kato, Y, Tsukuba, T, Okamoto, K
- Journal Title
  
  Eur J Pharmacol 580
  
  Pages: 70-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erthrocytes, and inhibition of hemaggelutination by an interdomain regional peptide.2007
- Author(s)
  Sakai, E., Naito, M., Sato, K., Hotokezaka, H., Kadowaki, T., Kamaguch, A., Yamamoto, K., Okamoto, K., Nakayama, K.
- Journal Title
  
  J. Bacteriol. 189
  
  Pages: 3977-3986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Cathepsin E Prevents Tumor Growth and Metastasis by Catalyzing the Proteolytic Release of Soluble TRAIL from Tumor Cell2007
- Author(s)
  Kawakubo T., Okamoto K., Iwata J., Shin M., Okamoto Y., Yasukochi A., Nakayama K.I., Kadowaki T., Tsukuba T., Yamamoto K.
- Journal Title
  
  Surface. Cancer Res. 67
  
  Pages: 10869-10878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E.2007
- Author(s)
  Kakehashi H., Nishioku T., Tsukuba T., Kadowaki T., Nakamura S., Yamamoto K.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 5728-5737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007
- Author(s)
  Kakehashi H, Nishioku T, Tsukuba T, Kadowaki T, Nakamura S, Yamamoto K.
- Journal Title
  
  J. Immunol 179
  
  Pages: 5728-5737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an inter-domain regional peptide2007
- Author(s)
  Sakai E, Naito M, Sato K, Hotokezaka H, Kadowaki T, Kamaguchi A, Yamamoto K, Okamoto K, Nakayama K.
- Journal Title
  
  J Bacteriol 189
  
  Pages: 3977-3986
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface2007
- Author(s)
  Kawakubo T, Okamoto K, Iwata J, Shin M, Okamoto Y, Yasukochi A, Nakayama KI, Kadowaki T, Tsukuba T, Yamamoto K.
- Journal Title
  
  Cancer Res. 67
  
  Pages: 10869-10878
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface2007
- Author(s)
  Kawakubo, T, Okamoto, K, Iwata, J, Shin, M, Okamoto, Y, Yasukochi, A, Nakayama, KI, Kadowaki, T, Tsukuba, T, Yamamoto, K
- Journal Title
  
  Cancer Res 67
  
  Pages: 10869-10878
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromon as gingicalis-infected cells.2007
- Author(s)
  Kadowaki, T., et. al.
- Journal Title
  
  Frontiers in Bioscience 12
  
  Pages: 4800-4809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis,identification of its target protein on erythrocytes,and inhibition of hemagglutination by an interdomain regional peptide2007
- Author(s)
  Sakai E, Naito M, Sato K, Hotokezaka H, Kadowaki T, Kamaguchi A, Yamamoto K, Okamoto K, Nakayama K.
- Journal Title
  
  J Bacteriol. 189
  
  Pages: 3977-3986
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Role for gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelilal cells.2007
- Author(s)
  Yamatake, K., Maeda, M., Kadowaki, T., Takii, R., Tsukuba, T., Ueno, T., Kominami, E., Yokota, S., Yamamoto, K.
- Journal Title
  
  Infect. Immun. 75
  
  Pages: 2090-2100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] The role for Gingipains in Porphyromonas gingivalis traffic to phagol ysosomes and survival in human aortic endothelial cells2007
- Author(s)
  Yamatake K., Maeda M., Kadowaki T., Takii, R., Tsukuba T., Ueno T., Kominami, E., Yokota S., Yamamoto K.
- Journal Title
  
  Infect.Immun 75
  
  Pages: 2090-2100
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingivalis-infected cells2007
- Author(s)
  Kadowaki, T, Takii, R, Yamatake, K, Kawakubo, T, Tsukuba, T, Yamamoto, K
- Journal Title
  
  Front Biosci 12
  
  Pages: 4800-48009
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases.2007
- Author(s)
  Kanaji, S., Tanaka, Y., Sakata, Y., Takeshita, K., Arima, K., Ohta, S., Hansell, E.J., Caffrey, C., Mottram, J.C., Lowther, J., Donnelly, S., Stack, C., Kadowaki, T., Yamamoto, K., McKerrow, J.H., Dalton, J.P., Coombs, G.H., Izuhara, K.
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 4260-4264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] The role for Gingipains in Porphyromonas gingivalis traffic to phagolysosomes and survival in human aortic endothelial cells2007
- Author(s)
  Yamatake, K, Maeda, M, Kadowaki, T, Takii, R, Tsukuba, T, Ueno, T, Kominami, E, Yokota, S, Yamamoto, K
- Journal Title
  
  Infect Immun 75
  
  Pages: 2090-2100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses2007
- Author(s)
  Shin M, Kadowaki T, Iwata J, Kawakubo T, Yamaguchi N, Takii R, Tsukuba T, Yamamoto K.
- Journal Title
  
  Biol Chem. 388
  
  Pages: 1173-1181
- NAID
  120006900037
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Construction of recombinant hemagglutinin derived from the gingipain-encoding gene of Porphyromonas gingivalis, identification of its target protein on erythrocytes, and inhibition of hemagglutination by an interdomain regional peptide2007
- Author(s)
  Sakai, E, Naito, M, Sato, K, Hotokezaka, H, Kadowaki, T, Kamaguchi, A, Yamamoto, K, Okamoto, K, Nakayama, K
- Journal Title
  
  J Bacteriol 189
  
  Pages: 3977-3986
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007
- Author(s)
  Kakehashi H, Nishioku T, Tsukuba T, Kadowaki T, Nakamura S, Yamamoto K.
- Journal Title
  
  J Immunol. 179
  
  Pages: 5728-5737
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Gene expression profiling of mammary glands of cathepsin E-deficient mice compared with wild-type littermates2007
- Author(s)
  Kawakubo T, Yasukochi A, Tsukuba T, Kadowaki T, Yamamoto K.
- Journal Title
  
  Biochimie. 90
  
  Pages: 396-404
- NAID
  120006900027
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases2007
- Author(s)
  Kanaji S, Tanaka Y, Sakata Y, Takeshita K, Arima K, Ohta S, Hansell EJ, Caffrey C, Mottram JC, Lowther J, Donnelly S, Stack C, Kadowaki T, Yamamoto K, McKerrow JH, Dalton JP, Coombs GH, Izuhara K.
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 4260-4264
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder in macrophages showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH. *Both authors contributed equally to this work2007
- Author(s)
  Yanagawa, M*, Tsukuba, T*, Nishioku, T, Okamoto, Y, Okamoto, K, Takii, R, Terada, Y, Nakayama, KI, Kadowaki, T, Yamamoto, K
- Journal Title
  
  J. Biol Chem 282
  
  Pages: 1851-1862
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cystatin C stimulates the differentiation of mouse osteoblastic cells and bone formation2007
- Author(s)
  Danjo, A, Yamaza, T, Kido, MA, Shimohira, D, Tsukuba, T, Kagiya, T, Yamashita, Y, Nishijima, K, Masuko, S, Goto, M, Tanaka, T
- Journal Title
  
  Biochem Biophys Res Commun 360
  
  Pages: 199-204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder 5 showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in macrophages.2007
- Author(s)
  Yanagawa, M., Tsukuba, T., Nishioku, T., Okamoto, Y., Okamoto, K., Takii, R., Terada, Y., Nakayama, K.T., Kadowaki, T., Yamamoto, K
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 1851-1862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses.2007
- Author(s)
  Shin, M., Kadowaki, T., Iwata, J., Kawakubo, T., Yamaguchi, N., Takii, R., Tsukuba, T., Yamamoto, K.
- Journal Title
  
  Biol. Chem. 388
  
  Pages: 1173-1181
- NAID
  120006900037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases2007
- Author(s)
  Kanaji, S, Tanaka, Y, Sakata, Y, Takeshita, K, Arima, K, Ohta, S, Hansell, EJ, Caffrey, C, Mottram, JC, Lowther, J, Donnelly, S, Stack, C, Kadowaki, T, Yamamoto, K, McKerrow, JH, Dalton, JP, Coombs, GH, Izuhara, K
- Journal Title
  
  FEBS Lett 581
  
  Pages: 4260-4264
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses2007
- Author(s)
  Shin, M, Kadowaki, T, Iwata, J, Kawakubo, T, Yamaguchi, N, Takii, R, Tsukuba, T, Yamamoto, K
- Journal Title
  
  Biol Chem 388
  
  Pages: 1173-1181
- NAID
  120006900037
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] The Role for Gingipains in Porphyromonas gingivalis Traffic to Phagolysosomes and Survival in Human Aortic Endothelial Cells2007
- Author(s)
  Yamatake K, Maeda M, Kadowaki T, Takii R, Tsukuba T, Ueno T, Kominami E, Yokota S, Yamamoto K
- Journal Title
  
  Infect. Immun 75
  
  Pages: 2090-2100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592148
[Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder in macrophages showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH2007
- Author(s)
  Yanagawa M, Tsukuba T, et. al.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 1851-1862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cystatin C stimulates the differentiation of mouse osteoblastic cells and bone formation2007
- Author(s)
  Danjo A, Yamaza T, Kido MA, Shimohira D, Tsukuba T, Kagiya T, Yamashita Y, Nishijima K, Masuko S, Goto M, Tanaka T.
- Journal Title
  
  Biochem Biophys Res Commun 360
  
  Pages: 199-204
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingivalis-infected cells2007
- Author(s)
  Kadowaki T, Takii R, Yamatake K, Kawakubo T, Tsukuba T, Yamamoto K
- Journal Title
  
  Front Biosci 12
  
  Pages: 4800-4809
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E2007
- Author(s)
  Kakehashi, H, Nishioku, T, Tsukuba, T, Kadowaki, T, Nakamura, S, Yamamoto, K
- Journal Title
  
  J Immunol 179
  
  Pages: 5728-5737
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] A role for gingipains in cellular responses and bacterial survival in Porphyromonas gingicalis-infected cells.2007
- Author(s)
  Kadowaki, T., Takii, R., Yamatake, K., Kawakubo, T., Tsukuba, T., Yamamoto, K.
- Journal Title
  
  Frontiers in Biosci. 12
  
  Pages: 4800-4809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209058
[Journal Article] Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure2006
- Author(s)
  Hashimoto, M, Kadowaki, T, Tsukuba, T, Yamamoto, K
- Journal Title
  
  J. Biochein 140
  
  Pages: 713-723
- NAID
  10018841154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors.2006
- Author(s)
  T.Tsukuba, et al.
- Journal Title
  
  J.Biochem. (in press)
- NAID
  10018843713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways2006
- Author(s)
  Hu JP, Nishishita K, Sakai E, Yoshida H, Kato Y, Tsukuba T, Okamoto K.
- Journal Title
  
  Eur J Pharmacol. 580
  
  Pages: 70-79
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation, expressed in human embryonic kidney 293T cells.2006
- Author(s)
  Tsukuba T et al.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Data Source
  KAKENHI-PROJECT-16591859
[Journal Article] Up-regulation, and enhanced maturation and secretion of cathepsin E in mouse macrophages treated with interferon-γ or lipopolysaccharide2006
- Author(s)
  Yanagawa, M, Tsukuba, T, Okamoto, K, Terada, Y, Kadowaki, T, Yamamoto, K
- Journal Title
  
  J. Oral Biosci 48
  
  Pages: 218-225
- NAID
  10018041983
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder in macrophages showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH2006
- Author(s)
  Yanagawa M^*., Tsukuba T^*., Nishioku T, Okamoto Y. Okamoto K., Takii R., Terada Y, Nakayama KI., Kadowaki T, Yamamoto K.
- Journal Title
  
  J.Biol Chem. 282
  
  Pages: 1851-1862
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Characterization of rat cathepsin E and its mutants changing active site residues and lacking pro^parts and N-glucosylation expressed in human embryonic kidney 293T cells.2006
- Author(s)
  Tsukuba, T. et al.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Characterization of rat cathepsin E and its mutants changing active site residues and lacking pro^parts and N-glucosylation expressed in human embryonic kidney 293T cells.2006
- Author(s)
  Tsukuba, T. et al.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Data Source
  KAKENHI-PROJECT-16659514
[Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation, expressed in human embryonic kidney 293T cells.2006
- Author(s)
  Tsukuba T. et al.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591859
[Journal Article] Characterization of rat cathepsin E and its mutants changing active site residues and lacking pro^parts and N-glucosylation expressed in human embryonic kidney 293T cells.2006
- Author(s)
  tsukuba, T. et al.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure2006
- Author(s)
  Hashimoto M, Kadowaki T, Tsukuba T., Yamamoto K.
- Journal Title
  
  J.Biochem. 140
  
  Pages: 713-723
- NAID
  10018841154
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors2006
- Author(s)
  Tsukuba T., Yamamoto S., Yanagawa M., Okamoto K, Okamoto K., Nakayama KI, Kadowaki T, Yamamoto K.
- Journal Title
  
  J.Biochem. 140
  
  Pages: 57-66
- NAID
  10018843713
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycoSylation expressed in human embryonic kidney 293T cells2006
- Author(s)
  Tsukuba, T, Ikeda, S, Okamoto, K, Yasuda, Y, Sakai, E, Kadowaki, T, Sakai, H, Yamamoto, K
- Journal Title
  
  FEBS J 273
  
  Pages: 219-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors.2006
- Author(s)
  Tsukuba T., Yamamoto S., et al.
- Journal Title
  
  J. Biochem. 140巻
  
  Pages: 57-66
- NAID
  10018843713
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation expressed in human embryonic kidney 293T cells2006
- Author(s)
  Tsukuba T., Ikeda S., Okamoto K. Yasuda Y, Sakai E, Kadowaki T., Sakai H., Yamamoto K.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation, espressed in human kidney 293T cells.embryonic2006
- Author(s)
  Tsukuba T et al.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591859
[Journal Article] Characterization of rat cathepsin E and its mutants changing active site residues and lacking pro^parts and N -glucosylation expressed in human embryonic kidney 293T cells.2006
- Author(s)
  T.Tsukuba, et al.
- Journal Title
  
  FEBS J. 273
  
  Pages: 219-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors2006
- Author(s)
  Tsukuba, T, Yamamoto, S, Yanagawa, M, Okamoto, K, Okamoto, K, Nakayama, KI, Kadowaki, T, Yamamoto, K
- Journal Title
  
  J. Biochem 140
  
  Pages: 57-66
- NAID
  10018843713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E deficiency induces a novel form of lysosomal storage disorder in macrophages showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH.2006
- Author(s)
  Yanagawa M, Tsukuba T. et al.
- Journal Title
  
  J. Biol Chem. 282巻
  
  Pages: 1851-1862
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation expressed in human embryonic kidney 293T cells.2006
- Author(s)
  Tsukuba T., Ikeda S., et al.
- Journal Title
  
  FEBS J. 273巻
  
  Pages: 216-229
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Selective proteolysis of apolipoprotein B-100 by Arg-gingipain mediates atherosclerosis progression accelerated by bacterial exposure.2006
- Author(s)
  Hashimoto M, Kadowaki T, et al.
- Journal Title
  
  J. Biochem. 140巻
  
  Pages: 713-723
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors.2006
- Author(s)
  Tsukuba, T. et al.
- Journal Title
  
  J. Biochem. (In press)
- NAID
  10018843713
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Up-regulation, and enhanced maturation and secretion of cathepsin E in mouse macrophages treated with interferon-g or lipopolysaccharide.2006
- Author(s)
  Yanagawa M, Tsukuba T et al.
- Journal Title
  
  J. Oral Biosci. 48巻
  
  Pages: 218-225
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Up-regulation,and enhanced maturation and secretion of cathepsin E in mouse macrophages treated with interferon-y or lipopolysaccharide2006
- Author(s)
  Yanagawa M., Tsukuba T, Okamoto K., Terada Y, Kadowaki T, Yamamoto K
- Journal Title
  
  J.Oral Biosci. 48
  
  Pages: 218-225
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.2004
- Author(s)
  Kadowaki, T. et al.
- Journal Title
  
  Mol.Pharmacol. 66
  
  Pages: 1599-1606
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed ainaipain inhibitors.2004
- Author(s)
  Kadowaki T. et al.
- Journal Title
  
  Mol.Pharmacol. 66
  
  Pages: 1599-1606
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591859
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.2004
- Author(s)
  Kadowaki, T.
- Journal Title
  
  Mol.Pharmacol. 66
  
  Pages: 1599-1606
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Suppresstion of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.2004
- Author(s)
  Kadowaki T et al.
- Journal Title
  
  Mol. Pharmacol. 66
  
  Pages: 1599-1606
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591859
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.2004
- Author(s)
  Kadowaki, T.et al.
- Journal Title
  
  Mol.Pharmacol. 66
  
  Pages: 1599-1606
- Data Source
  KAKENHI-PROJECT-16659514
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.2004
- Author(s)
  Kadowaki, T. et al.
- Journal Title
  
  Mol.Pharmacol. 66
  
  Pages: 1599-1606
- Data Source
  KAKENHI-PROJECT-12146203
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.2004
- Author(s)
  Kadowaki, T. et al.
- Journal Title
  
  Mol.Pharmacol. 66
  
  Pages: 1599-1606
- Data Source
  KAKENHI-PROJECT-16591859
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.2004
- Author(s)
  Kadowaki, T.et al.
- Journal Title
  
  Mol.Pharmacol. 66
  
  Pages: 1599-1606
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors2004
- Author(s)
  Kadowaki, T. et al.
- Journal Title
  
  Mol. Pharmacol. 66
  
  Pages: 1599-1606
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors.2004
- Author(s)
  T.Kadowaki, et al.
- Journal Title
  
  Mol.Pharmacol. 66
  
  Pages: 1599-1606
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Association of cathepsin E deficiency with development of atopic dermatitis.2003
- Author(s)
  T.Tsukuba, et al.
- Journal Title
  
  J.Biochem. 134
  
  Pages: 893-902
- NAID
  10012060070
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Isolation and characterization of a novel and potent inhibitor of Arg-gingipain from Strepromyces sp. Strain FA-70.2003
- Author(s)
  Kadowaki, T. et al.
- Journal Title
  
  Biol.Chem. 384
  
  Pages: 911-920
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Association of cathepsin E deficiency with development of atopic dermatitis.2003
- Author(s)
  Tsukuba T.
- Journal Title
  
  J.Biochem. 134
  
  Pages: 893-902
- NAID
  10012060070
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Periodontal Diseases and Gingipains2003
- Author(s)
  Kadowaki, T.
- Journal Title
  
  Folia Pharmacol.Jpn. 122
  
  Pages: 37-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Association of cathepsin E deficiency of atopic dermatitis.2003
- Author(s)
  Tsukuba T., et al.
- Journal Title
  
  J. Biochem. 134
  
  Pages: 893-902
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Association of cathepsin E deficiency with development of atopic dermatitis.2003
- Author(s)
  Tsukuba T. et al.
- Journal Title
  
  J.Biochem. 134
  
  Pages: 893-902
- NAID
  10012060070
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Isolation and characterization of a novel and potent inhibitor of Arg-gingipain from Strepromyces sp.Strain FA-70.2003
- Author(s)
  T.Kadowaki, et al.
- Journal Title
  
  Biol.Chem. 384
  
  Pages: 911-920
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Suppression of virulence of Porphyromonas gingivalis by potent inhibitors specific for gingipains.2003
- Author(s)
  T.Kadowaki, et al.
- Journal Title
  
  Current Protein Peptide Sci. 4
  
  Pages: 451-458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Periodontal Diseases and Gingipains2003
- Author(s)
  T.Kadowaki
- Journal Title
  
  Folia Pharmacol.Jpn. 122
  
  Pages: 37-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] 歯周病とジンジパイン2003
- Author(s)
  門脇知子
- Journal Title
  
  日本薬理学会誌 122
  
  Pages: 37-44
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Isolation and characterization of a novel and potent inhibitor of Arg-gingipain from Strepromyces sp. Strain FA-70.2003
- Author(s)
  Kadowaki, T.
- Journal Title
  
  Biol.Chem. 384
  
  Pages: 911-920
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Suppression of virulence of Porphyromonas gingivalis by potent inhibitors specific for gingipains.2003
- Author(s)
  Kadowaki T.
- Journal Title
  
  Current Protein Peptide Sci. 4
  
  Pages: 451-458
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Suppression of virulence of Porphyromonas gingivalis by potent inhibitors specific for gingipains.2003
- Author(s)
  Kadowaki T., et al.
- Journal Title
  
  Current Protein Peptide Sci. 4
  
  Pages: 451-458
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Suppression of virulence of Porphyromonas gingivalis by potent inhibitors specific for gingipains.2003
- Author(s)
  Kadowaki T. et al.
- Journal Title
  
  Current Protein Peptide Sci. 4
  
  Pages: 451-458
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Atopic Dermatitis and Cathepsin E2003
- Author(s)
  Tsukuba, T.
- Journal Title
  
  Folia Pharmacol.Jpn. 122
  
  Pages: 15-20
- NAID
  10011598301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] アトピー性皮膚炎とカテプシンE2003
- Author(s)
  筑波隆幸
- Journal Title
  
  日本薬理学会誌 122
  
  Pages: 15-20
- NAID
  10011598301
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Atopic Dermatitis and Cathepsin E2003
- Author(s)
  T.Tsukuba
- Journal Title
  
  Folia Pharmacol.Jpn. 122
  
  Pages: 15-20
- NAID
  10011598301
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Isolation and characterization of a novel and potent inhibitor of Arg-gingipain from Strepromyces sp. Strain FA-70.2003
- Author(s)
  Kadowaki, T., et al.
- Journal Title
  
  Biol. Chem. 384
  
  Pages: 911-920
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209062
[Journal Article] Chaperon interactions of the metalloproteinase meprin A in the secretory or proteasomal-degradative pathway.2002
- Author(s)
  Tsukuba, T.
- Journal Title
  
  Arch.Biochem.Biophys. 392
  
  Pages: 192-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Chaperon interactions of the metalloproteinase meprin A in the secretory or proteasomal-degradative pathway.2002
- Author(s)
  Tsukuba, T. et al.
- Journal Title
  
  Arch.Biochem.Biophys. 392
  
  Pages: 192-198
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Journal Article] Nueronal Diseases and Intracellular Aspartic Proteinases2001
- Author(s)
  Tsukuba, T.
- Journal Title
  
  Protein, Nucleic Acid and Enzyme
  
  Pages: 2034-2041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13357016
[Presentation] Rab44はコラーゲン抗体誘発性関節炎において炎症反応を制御する2023
- Author(s)
  山口優、門脇知子、坂井詠子、野黒美麻由子、親川駿、日浅匠、馬渡遥香、筑波隆幸
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27808
[Presentation] Rab44は筋衛星細胞におけるmTORC1シグナル伝達と融合制御因子の輸送の調節により筋再生を負に制御する2023
- Author(s)
  親川駿、山口優，門脇知子，坂井詠子, 野黒美麻由子, 谷本あゆ子, 筑波　隆幸
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rufy4のRUNドメイン欠失変異体は糸状仮足形成を促進し破骨細胞の骨吸収を抑制する2023
- Author(s)
  坂井詠子, 小柳悠, Fatima Farhana, 山口優, 筑波隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] 滑走運動細菌 Flavobacterium collinsii のコロニー拡張2023
- Author(s)
  佐藤啓子、近藤好夫、佐藤主税、内藤真理子、門脇知子
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27808
[Presentation] Dennd2cは破骨細胞分化を負に制御する2023
- Author(s)
  小栁　悠、坂井　詠子、山口　優、Farhana Fatima、平　曜輔、村田比呂司、筑波　隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Dennd2cは破骨細胞分化を負に制御する2023
- Author(s)
  小柳悠, 坂井詠子, 山口優, ファルハナ・ファティマ , 山田志津香, 介田圭, 江越貴文, 平曜輔, 村田比呂司, 筑波隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] Rab44はmTORC1シグナルを制御することで筋芽細胞の分化を負に制御する2023
- Author(s)
  谷本あゆ子, 山口優, 門脇知子, 坂井詠子, 親川駿, 筑波隆幸, 吉田教明
- Organizer
  第６５回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] Rab44は筋衛星細胞におけるmTORC1シグナル伝達と融合制御因子の輸送の調節により筋再生を負に制御する2023
- Author(s)
  親川駿、山口優、門脇知子、坂井詠子、野黒美麻由子、谷本あゆ子、筑波隆幸
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27808
[Presentation] Rab44欠損はニッケルアレルギーに対して減弱した免疫反応を惹起する2023
- Author(s)
  野黒美麻由子、山口優、佐藤啓子、親川駿、筑波隆幸、門脇知子
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27808
[Presentation] Rufy4のRUNドメイン欠失変異体は糸状仮足形成を促進し破骨細胞の骨吸収を抑制する2023
- Author(s)
  坂井詠子, 小栁悠, Farhana Fatima, 山口優，筑波隆幸
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rab44はmTORC1シグナルを制御することで筋芽細胞の分化を負に制御する2023
- Author(s)
  谷本あゆ子、山口優，門脇知子，坂井詠子, 親川駿, 筑波隆幸
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rab44はコラーゲン抗体誘発性関節炎において炎症反応を制御する2023
- Author(s)
  山口　優，門脇　知子，坂井　詠子，野黒美　麻由子，親川　駿, 日浅　匠，馬渡　遥香，筑波　隆幸
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rab44はmTORC1シグナルを制御することで筋芽細胞の分化を負に制御する2023
- Author(s)
  谷本あゆ子、山口優、門脇知子、坂井詠子、親川駿、筑波隆幸
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27808
[Presentation] Rab44欠損はニッケルアレルギーに対して減弱した免疫反応を惹起する2023
- Author(s)
  野黒美麻由子, 山口優, 佐藤啓子, 親川駿, 筑波隆幸, 門脇知子, 村田比呂司
- Organizer
  第６５回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] 筋衛星細胞におけるmTORC1シグナル伝達と融合制御因子の輸送の調節により、筋再生を負に制御する2023
- Author(s)
  親川駿, 山口優, 門脇知子, 坂井詠子, 野黒美麻由子, 谷本あゆ子, 筑波隆幸, 村田比呂司
- Organizer
  第６５回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] 滑走運動細菌Flavobacterium collinsiiのコロニー拡張2023
- Author(s)
  佐藤啓子, 近藤好夫, 佐藤主税, 内藤真理子, 門脇知子
- Organizer
  第６５回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] 滑走運動細菌によるバイオフィルム拡張2022
- Author(s)
  佐藤啓子, 近藤好夫, 内藤真理子, 門脇知子, 佐藤主税
- Organizer
  第６４回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] Rufy4はRUNドメインを介して破骨細胞による骨吸収を制御する2022
- Author(s)
  坂井詠子, Farhana Fatima, 小栁悠, 山口優，筑波隆幸
- Organizer
  第95回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] Coronin1CはGDP特異的Rab44エフェクターでありマクロファージの細胞運動を調節することで破骨細胞形成を制御する2022
- Author(s)
  山口優，門脇知子，相原希美，大山要，岡元邦彰，坂井詠子，筑波隆幸
- Organizer
  第95回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] Rufy4はRUNドメインを介して破骨細胞による骨吸収を制御する2022
- Author(s)
  坂井詠子, Farhana Fatima, 小栁悠, 山口優，筑波隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] 滑走細菌の病原性2022
- Author(s)
  近藤好夫, 内藤真理子, 門脇知子, 佐藤啓子
- Organizer
  第６４回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] 金属アレルギーでの高分子量Gタンパク質Rab44の役割2022
- Author(s)
  野黒美麻由子、山口優、佐藤啓子、村田比呂司、筑波隆幸、門脇知子
- Organizer
  第4５回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] Coronin1CはGDP特異的Rab44エフェクターでありマクロファージの細胞運動を調節することで破骨細胞形成を制御する2022
- Author(s)
  山口　優，門脇　知子，相原　希美，大山　要，岡元　邦彰，坂井　詠子，筑波　隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] 金属アレルギーでの高分子量Gタンパク質Rab44の役割2022
- Author(s)
  野黒美麻由子、山口優、佐藤啓子、村田比呂司、筑波隆幸、門脇知子
- Organizer
  第4５回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] 高分子量Rabタンパク質による筋衛星細胞と筋形成過程に及ぼす影響2022
- Author(s)
  親川駿、山口優，門脇知子，谷本あゆ子, 坂井詠子，村田比呂司、筑波隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] Rab44タンパク質による炎症応答制御機構2022
- Author(s)
  門脇知子、山口　優、佐藤啓子、筑波隆幸
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] 高分子量Rabタンパク質が制御する筋芽細胞から筋管への分化機構2022
- Author(s)
  谷本　あゆ子，山口　優，門脇　知子，親川駿, 坂井　詠子，小野悠介，吉田　教明，筑波　隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] 高分子量Rabタンパク質が制御する筋芽細胞から筋管への分化機構2022
- Author(s)
  谷本　あゆ子，山口　優，門脇　知子，親川駿, 坂井　詠子，小野悠介，吉田　教明，筑波　隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] Rab44タンパク質による炎症応答制御機構2022
- Author(s)
  門脇知子、山口優、佐藤啓子、筑波隆幸
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] Coronin1CはGDP特異的Rab44エフェクターでありマクロファージの細胞運動を調節することで破骨細胞形成を制御する2022
- Author(s)
  山口　優，門脇　知子，相原　希美，大山　要，岡元　邦彰，坂井　詠子，筑波　隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] Rab44タンパク質による炎症応答制御機構2022
- Author(s)
  門脇知子、山口　優、佐藤啓子、筑波隆幸
- Organizer
  第64回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] 高分子量Rabタンパク質が制御する筋芽細胞から筋管への分化機構2022
- Author(s)
  谷本あゆ子，山口優，門脇知子，親川駿, 坂井詠子，小野悠介，吉田教明，筑波隆幸
- Organizer
  第95回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] 高分子量Rabタンパク質による筋衛星細胞と筋形成過程に及ぼす影響2022
- Author(s)
  親川駿、山口優，門脇知子，谷本あゆ子, 坂井詠子，村田比呂司、筑波隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10047
[Presentation] 高分子量Rabタンパク質による筋衛星細胞と筋形成過程に及ぼす影響2022
- Author(s)
  親川駿、山口優，門脇知子，谷本あゆ子, 坂井詠子，村田比呂司、筑波隆幸
- Organizer
  第95回生化学会大会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] Rufy4はRUNドメインを介して破骨細胞による骨吸収を制御する2022
- Author(s)
  坂井詠子, Farhana Fatima, 小栁悠, 山口優，筑波隆幸
- Organizer
  第９５回生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] 金属アレルギーでの高分子量Gタンパク質Rab44の役割2022
- Author(s)
  野黒美麻由子、山口優、佐藤啓子、村田比呂司、筑波隆幸、門脇知子
- Organizer
  第45回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K09844
[Presentation] リソソームとアレルギー疾患制御2020
- Author(s)
  門脇知子、山口　優、筑波隆幸
- Organizer
  第62回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03860
[Presentation] リソソームとアレルギー疾患制御2020
- Author(s)
  門脇知子、山口　優、筑波隆幸
- Organizer
  第62回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K10112
[Presentation] A T9SS cargo protein involved in regulation of the T9SS expression in Porphyromonas gingivalis2018
- Author(s)
  雪竹英治, 反田祐介, 門脇知子, 佐藤啓子, 庄子幹郎, 内藤真理子, 今田勝巳, 中山浩次
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K15776
[Presentation] Effects of deficiency of Kelch-like ECH-associated protein 1 on osteoclastogenesis by constitutive activation of nuclear factor E2 p45-related factor 2.2018
- Author(s)
  Sakai E, Yamaguchi Y, Fukuma Y, Nishishita K, Tsukuba T
- Organizer
  18th World congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] A T9SS cargo protein involved in regulation of the T9SS expression in Porphyromonas gingivalis2018
- Author(s)
  Hideharu Yukitake, Yusuke Handa, Tomoko Kadowaki, Keiko Sato, Mikio Shoji, Mariko Naito, Katsumi Imada, Koji Nakayama
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] マウスにおけるRab44の組織分布および発現変動の解析2018
- Author(s)
  徳久美都子, 門脇知子, 小川晃平, 山口優, 梅田正博, 筑波隆幸
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 破骨細胞分化を負に制御するRabタンパク質の同定2018
- Author(s)
  奥舎有加, 板垣まみ, 十川千春, 江口傑徳，坂井詠子, 筑波隆幸, 岡元邦彰
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] Rab44タンパク質の細胞内局在とその制御に関する解析2018
- Author(s)
  小川晃平, 門脇知子, 山口優, 徳久美都子, 梅田正博, 筑波隆幸
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] Rab44タンパク質の細胞内局在とその制御に関する解析2018
- Author(s)
  小川晃平、門脇知子、徳久美都子、山口優、梅田正博、筑波隆幸
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K09536
[Presentation] マウスにおけるRab44の組織分布および発現変動の解析2018
- Author(s)
  徳久美都子、門脇知子、小川晃平、山口優、梅田正博、筑波隆幸
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K09536
[Presentation] Keap1遺伝子欠損はIrf8とMafBの発現上昇を介して破骨細胞分化を抑制する2017
- Author(s)
  坂井詠子，福間裕，西下一久，岡元邦彰，筑波隆幸
- Organizer
  第59回日本歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Rutaecarpineの破骨細胞分化抑制効果2017
- Author(s)
  福間裕, 坂井詠子, 小巻俊介, 西下一久, 岡元邦彰, 筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 新規高分子量Gタンパク質Rab44はCa2+流入及びNFATc1経路を介して破骨細胞分化を負に制御する2017
- Author(s)
  山口　優, 坂井詠子, 岡元邦彰, 鍛冶屋　裕, 岡部幸司, 門脇知子, 筑波隆幸
- Organizer
  生命科学系学会合同年会ConBio2017
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] ヘムオキシゲナーゼ1の発現抑制はカスパーゼ3の活性化、HMGB1の細胞外遊離と破骨細胞分化に必要である2017
- Author(s)
  坂井詠子, 岡元邦彰, 筑波隆幸
- Organizer
  第59回日本歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Keap1遺伝子欠損はin vivoおよびin vitroにおいて骨の細胞分化を抑制する2017
- Author(s)
  坂井詠子，福間裕，西下一久，岡元邦彰，筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] エンドソーム・リソソーム機能と骨細胞2017
- Author(s)
  筑波隆幸
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール・長崎新聞文化ホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Invited
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Rutaecarpineの破骨細胞分化抑制効果2017
- Author(s)
  福間裕、坂井詠子、小巻俊介、西下一久、岡元邦彰、筑波隆幸
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール・長崎新聞文化ホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Keap1遺伝子欠損はin vivoおよびin vitroにおいて骨の細胞分化を抑制する2017
- Author(s)
  坂井詠子、福間裕、西下一久、岡元邦彰、筑波隆幸
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール・長崎新聞文化ホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Keap1遺伝子欠損はNrf2の活性化を介して破骨細胞分化を抑制する2017
- Author(s)
  坂井詠子, 福間裕, 西下一久, 岡元邦彰, 筑波隆幸
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Keap1遺伝子欠損はNrf2の活性化を介して破骨細胞分化を抑制する2017
- Author(s)
  坂井詠子, 福間裕, 西下一久, 岡元邦彰, 筑波隆幸
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] Porphyromonas gingivalis IX型分泌機構の調節メカニズムに関与する分子の解析2017
- Author(s)
  雪竹英治、門脇知子、内藤真理子、佐藤啓子、庄子幹郎、中山浩次
- Organizer
  第90回日本細菌学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-16K15776
[Presentation] Cathepsin K regulates invasion, migration, and adhesion of oral squamous cell carcinomas2017
- Author(s)
  山下健太郎、岩竹真弓、岡元邦彰、山田慎一、梅田正博、筑波隆幸
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール・長崎新聞文化ホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 破骨細胞分化を制御する新規Rabタンパク質の同定と機能解析2017
- Author(s)
  山口優，坂井詠子，岡元邦彰，鍛治屋浩，岡部幸司、門脇知子，筑波隆幸
- Organizer
  第59回日本歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] Keap1遺伝子欠損はIrf8とMafBの発現上昇を介して破骨細胞分化を抑制する2017
- Author(s)
  坂井詠子，福間裕，西下一久，岡元邦彰，筑波隆幸
- Organizer
  第59回日本歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 破骨細胞分化を制御する新規Rabタンパク質の同定と解析2017
- Author(s)
  山口　優, 坂井詠子, 岡元邦彰, 門脇知子,筑波隆幸
- Organizer
  第22回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] カテプシンKは口腔扁平上皮癌の転移、遊走、接着を制御する2017
- Author(s)
  山下健太郎, 岩竹真弓, 山田慎一, 岡元邦彰，梅田正博, 筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] The critical roles of gingipains in cell migration and inflammatory responses of microglia through activation of protease-activated receptor-2 (PAR-2)2017
- Author(s)
  Yicong Liu, Zhou Wu, Tomoko Kadowaki, Hiroshi Nakanishi
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県・長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] Porphyromonas gingivalis IX型分泌機構の調節メカニズムに関与する分子の解析2017
- Author(s)
  雪竹英治, 門脇知子, 内藤真理子, 庄子幹郎, 菊池有一郎, 中山浩次
- Organizer
  第９０回日本細菌学会総会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] コバルトプロトポルフィリンの破骨細胞分化および活性化に対する影響2017
- Author(s)
  岡元邦彰，坂井詠子，筑波隆幸
- Organizer
  メタルバイオサイエンス研究会2017
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 歯科レジンモノマーHEMA及びTEGDMAは低い細胞毒性で破骨細胞抑制活性を持つ2017
- Author(s)
  稲光宏之, 岡元邦彰，坂井詠子, 西下一久，村田比呂司, 筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] エンドソーム・リソソーム機能と骨細胞2017
- Author(s)
  筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 破骨細胞分化を制御する新規Rabタンパク質の同定と解析2017
- Author(s)
  山口優, 坂井詠子, 岡元邦彰, 門脇知子, 筑波隆幸
- Organizer
  第 22 回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] Keap1遺伝子欠損はin vivoおよびin vitroにおいて骨の細胞分化を抑制する2017
- Author(s)
  坂井詠子，福間裕，西下一久，岡元邦彰，筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] コバルトプロトポルフィリンの破骨細胞分化および活性化に対する影響2017
- Author(s)
  岡元邦彰，坂井詠子，筑波隆幸
- Organizer
  メタルバイオサイエンス研究会2017
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 破骨細胞分化を負に制御する新規Kelchタンパク質の同定と機能解析2017
- Author(s)
  楢原　峻, 坂井詠子, 山口　優, 楢原春菜, 門脇知子, 岡元邦彰, 朝比奈　泉, 筑波隆幸
- Organizer
  生命科学系学会合同年会ConBio2017
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] The dental resin monomers HEMA and TEGDMA have inhibitory effects on osteoclast differentiation with low cytotoxicity2017
- Author(s)
  稲光宏之、岡元邦彰、坂井詠子、西下一久、村田比呂司、筑波隆幸
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール・長崎新聞文化ホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 新規高分子量Gタンパク質Rab44はCa2+流入及びNFATc1経路を介して破骨細胞分化を負に制御する2017
- Author(s)
  山口優，坂井詠子，岡元邦彰，鍛治屋浩，岡部幸司、門脇知子，筑波隆幸
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] Dihydroartemisininの破骨細胞分化抑制効果2017
- Author(s)
  小巻俊介、坂井詠子、福間裕、西下一久、岡元邦彰、筑波隆幸
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール・長崎新聞文化ホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 歯科レジンモノマーHEMA及びTEGDMAは低い細胞毒性で破骨細胞抑制活性を持つ2017
- Author(s)
  稲光宏之, 岡元邦彰，坂井詠子, 西下一久，村田比呂司, 筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] カテプシンKは口腔扁平上皮癌の転移、遊走、接着を制御する2017
- Author(s)
  山下健太郎, 岩竹真弓, 山田慎一, 岡元邦彰，梅田正博, 筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 扁平上皮癌細胞の増殖能・浸潤能・転移能における転写因子TFEBの役割2017
- Author(s)
  坂元　裕, 山下健太郎, 岡元邦彰, 門脇知子, 梅田正博, 筑波隆幸
- Organizer
  生命科学系学会合同年会ConBio2017
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] 扁平上皮癌細胞の増殖能・浸潤能・転移能における転写因子TFEBの役割2017
- Author(s)
  坂元裕, 山下健太郎, 岡元邦彰, 門脇知子, 梅田正博, 筑波隆幸
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Dihydroartemisininの破骨細胞分化抑制効果2017
- Author(s)
  小巻俊介, 坂井詠子, 福間裕, 西下一久, 岡元邦彰, 筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 扁平上皮癌細胞の増殖能・浸潤能・転移能における転写因子TFEBの役割2017
- Author(s)
  坂元裕, 山下健太郎, 岡元邦彰, 門脇知子, 梅田正博, 筑波隆幸
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 破骨細胞分化を制御する新規Rabタンパク質の同定と機能解析2017
- Author(s)
  山口優，坂井詠子，岡元邦彰，鍛治屋浩，岡部幸司、門脇知子，筑波隆幸
- Organizer
  第59回日本歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 新規高分子量Gタンパク質Rab44はCa2+流入及びNFATc1経路を介して破骨細胞分化を負に制御する2017
- Author(s)
  山口優，坂井詠子，岡元邦彰，鍛治屋浩，岡部幸司、門脇知子，筑波隆幸
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] KBTBD11, a novel BTB-Kelch protein, is a negative regulator of osteoclastogenesis through controlling Cullin3-mediated ubiquitination.2017
- Author(s)
  Narahara S, Sakai E, Kadowaki T, Yamaguchi Y, Narahara H, Okamoto K, Sumita Y, Asahina I, Tsukuba T
- Organizer
  2017 ASCB | EMBO Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] Rutaecarpineの破骨細胞分化抑制効果2017
- Author(s)
  福間裕, 坂井詠子, 小巻俊介, 西下一久, 岡元邦彰, 筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Actin-Binding LIM protein 1は破骨細胞における細胞骨格形成と細胞機能を制御する2017
- Author(s)
  楢原春菜, 坂井詠子, 岡元邦彰, 吉田教明, 筑波隆幸
- Organizer
  第59回日本歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 破骨細胞分化を負に制御する新規Kelchタンパク質の同定と機能解析2017
- Author(s)
  楢原峻, 坂井詠子, 山口優, 楢原春菜, 門脇知子, 岡元邦彰, 朝比奈泉,筑波隆幸
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Actin-Binding LIM protein 1は破骨細胞における細胞骨格形成と細胞機能を制御する2017
- Author(s)
  楢原春菜, 坂井詠子, 岡元邦彰, 吉田教明, 筑波隆幸
- Organizer
  第59回日本歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 破骨細胞分化を制御する新規Rabタンパク質の同定と解析2017
- Author(s)
  山口優, 坂井詠子, 岡元邦彰, 門脇知子, 筑波隆幸
- Organizer
  第 22 回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] ヘムオキシゲナーゼ1の発現抑制はカスパーゼ3の活性化、HMGB1の細胞外遊離と破骨細胞分化に必要である2017
- Author(s)
  坂井詠子, 岡元邦彰, 筑波隆幸
- Organizer
  第59回日本歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] 破骨細胞分化を負に制御する新規Kelchタンパク質の同定と機能解析2017
- Author(s)
  楢原峻, 坂井詠子, 山口優, 楢原春菜, 門脇知子, 岡元邦彰, 朝比奈泉,筑波隆幸
- Organizer
  第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H04379
[Presentation] Dihydroartemisininの破骨細胞分化抑制効果2017
- Author(s)
  小巻俊介, 坂井詠子, 福間裕, 西下一久, 岡元邦彰, 筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] エンドソーム・リソソーム機能と骨細胞2017
- Author(s)
  筑波隆幸
- Organizer
  第９０回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 破骨細胞におけるリソソーム/エンドソームに関与するタンパク質の同定とその機能解析2016
- Author(s)
  岩竹真弓，岡元邦彰，筑波隆幸
- Organizer
  第21回日本病態プロテアーゼ学会
- Place of Presentation
  千里ライフサエンスセンター（大阪府、豊中市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 骨芽細胞分化における転写因子TFEBの関与2016
- Author(s)
  岡元邦彰，坂井詠子，西下一久，筑波隆幸
- Organizer
  第58回日本歯科基礎医学会
- Place of Presentation
  札幌コンベンションセンター（北海道、札幌市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Keap1遺伝子欠損はIrf8の発現上昇を介して破骨細胞分化を抑制する2016
- Author(s)
  坂井詠子，福間裕，西下一久，岡元邦彰，筑波隆幸
- Organizer
  第58回日本歯科基礎医学会
- Place of Presentation
  札幌コンベンションセンター（北海道、札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] Porphyromonas gingivalis におけるIX 型分泌機構の調節メカニズムの解明2016
- Author(s)
  雪竹英治，門脇知子，内藤真理子，庄子幹郎，菊池有一郎，中山浩次
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪府・大阪市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] tert-ButylhydroquinoneによるIrf8とMafBの発現増加を介した破骨細胞分化抑制機構2016
- Author(s)
  坂井詠子，山口優，福間裕，西下一久，岡元邦彰，筑波隆幸
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター・東北大学川内北キャンパス（宮城県、仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] ヒト肝細胞内での脂肪滴はオートファジー‐リソソームシステムによる歯周病細菌排除に影響する2016
- Author(s)
  財津有未，岩竹真弓，佐藤啓子, 筑波隆幸
- Organizer
  第21回日本病態プロテアーゼ学会
- Place of Presentation
  千里ライフサエンスセンター（大阪府、豊中市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-16K15790
[Presentation] 歯周病原細菌P. gingivalisにおける病原性プロテアーゼ分泌の調節メカニズム2015
- Author(s)
  門脇知子, 雪竹英治, 佐藤啓子, 庄子幹郎, 内藤真理子, 中山浩次
- Organizer
  BMB2015 第38回日本分子生物学会年会第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15K11079
[Presentation] Porphyromonas gingivalis HBP35タンパク質の菌体表面局在化機構の解析2011
- Author(s)
  庄子幹郎、佐藤啓子、雪竹英治、近藤好夫、成田由香、門脇知子、内藤真理子、中山浩次
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  於長良川国際会議場
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-21592364
[Presentation] Porphyromonas gingivalis HBP35タンパク質の菌体表面局在化機構の解析2011
- Author(s)
  庄子幹郎、佐藤啓子、雪竹英治、近藤好夫、成田由香、門脇知子、内藤真理子、中山浩次
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-21592364
[Presentation] 抗菌物質非鉄金属ポルフィリンの取り込みに関与するP. gingivalis外膜タンパク質2010
- Author(s)
  雪竹英治、佐藤啓子、庄子幹郎、筑波(門脇)知子、内藤真理子、中山浩次
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  於タワーホール船堀
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21592364
[Presentation] Role of the C-terminal domain in a novel secretion system in Porphyromonas gingivalis2010
- Author(s)
  Mikio Shoji, Keiko Sato, Yuka Narita, Hideharu Yukitake, Tomoko Kadowaki, Mariko Naito, Koji Nakayama
- Organizer
  Role of the C-terminal domain in a novel secretion system in Porphyromonas gingivalis第83回日本細菌学会総会
- Place of Presentation
  於パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21592364
[Presentation] Characterization of a porK orthologue mutant in Tannerella forsythia2010
- Author(s)
  Yuka Narita, Mikio Shoji, Keiko Sato, Hideharu Yukitake, Tomoko Kadowaki, Mariko Naito1, Yukitaka Murakami Fuminobu Yoshimura, Koji Nakayama
- Organizer
  第83回日本細菌学会総会
- Place of Presentation
  於パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21592364
[Presentation] Impairment of autophagy accompanied by increased aberrant mitochondria and oxidative stress in cathepsin E-deficient macrophages2009
- Author(s)
  Tsukuba T., et al.
- Organizer
  第5回オートファジーに関する国際会議
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] カテブシンE欠損によるオートファジー低下とそれに伴うミトコンドリア機能低下と酸化ストレスの増大2009
- Author(s)
  筑波隆幸, 他
- Organizer
  第14回日本病態プロテアーゼ学会
- Place of Presentation
  大阪
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] カテプシンE欠損によるオートファジー低下とそれに伴うミトコンドリア機能低下と酸化ストレスの増大2009
- Author(s)
  筑波隆幸、柳川三千代、門脇知子、岡本美子、坂井詠子、岡元邦彰、山本健二
- Organizer
  第14回日本病態プロテアーゼ学会
- Place of Presentation
  於大阪
- Data Source
  KAKENHI-PROJECT-21592364
[Presentation] カテプシンE欠損マクロファージにおけるオートファジーの低下とそれに伴うミトコンドリア機能異常と酸化ストレスの上昇2009
- Author(s)
  筑波隆幸、門脇知子、坂井詠子、岡元邦彰、山本健二
- Organizer
  第51回歯科基礎医学会総会
- Place of Presentation
  於新潟
- Data Source
  KAKENHI-PROJECT-21592364
[Presentation] カテプシンE欠損マウスにおける高脂血症および脂肪肝の誘導2008
- Author(s)
  門脇知子, 他
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19592148
[Presentation] カテプシンE欠損による遊走能および細胞接着能の低下2008
- Author(s)
  筑波隆幸, 他
- Organizer
  歯科基礎医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] カテプシンE欠損はオートファジーの低下とそれに伴うミトコンドリア機能異常と酸化ストレスを引き起こす2008
- Author(s)
  筑波隆幸, 他
- Organizer
  日本分子生物学会・日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] カテプシンE欠損マウスにおける高脂血症および脂肪肝の誘導2008
- Author(s)
  門脇知子, 他
- Organizer
  歯科基礎医学会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] 「研究成果報告書概要(欧文)」より2007
- Author(s)
  Yamamoto, K, Tsukuba, T, Yanagawa, M, kakehashi, H, Kawakubo, T, Kadowaki, T
- Organizer
  10th International Symposium on Protease Inhibitor and Biological Control
- Place of Presentation
  Portoroz, Slovenia
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] P.gingivalis感染とインスリン抵抗性に関する実験的解析2007
- Author(s)
  門脇知子, 瀧井良祐, 筑波隆幸, 岡元邦彰, 山本健二
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンE欠損によるミトコンドリア機能異常と酸化ストレス亢進2007
- Author(s)
  筑波隆幸, 他
- Organizer
  第49回歯科基礎医学会
- Place of Presentation
  札幌・北海道大学
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles of cathepsin E in immune responses mediated by macrophages and dendritic cells2007
- Author(s)
  Yamamoto K., Tsukuba T., Yanagawa M., Kakehashi H., Kawakubo T., Kadowaki T
- Organizer
  10th International Symposium on Protease Inhibitor and Biological Control
- Place of Presentation
  Portoroz,Slovenia
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] CONTROL OF THE ENDOSOME/LYSOSOME SYSTEM OF MACROPHAGES BY CATHEPSIN E2007
- Author(s)
  Tsukuba, T, Okamoto, K, Kadowaki, K, Yamamoto, K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] 赤血球におけるカテプシンEの役割2007
- Author(s)
  岡元邦彰, 石田豊, 坂井詠子, 西下一久, 山本健二, 筑波隆幸
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] P.gingivalis感染とインスリン抵抗性に関する実験的解析2007
- Author(s)
  門脇知子, 他
- Organizer
  第49回歯科基礎医学会
- Place of Presentation
  北海道大学
- Year and Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Control of the endosome/lysosome system of macrophages by cathepsin E2007
- Author(s)
  筑波隆幸, 他
- Organizer
  5^<th> General Meeting of the International Proteolysis Society
- Place of Presentation
  ギリシア
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Roles for gingipains in atherosclerosis progression accelerated by bacterial exposure2007
- Author(s)
  Kadowaki, T, Takii, R, Hashimoto, M, Yamatake, K, Tsukuba, T, Yamamoto, K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] ASSOCIATION OF CATHEPSIN E WITH HOST DEFFENCE AGAINST TUMOR CELLS.(Symposium2007
- Author(s)
  Kawakubo, T, Yasukochi, A, Okamoto, K, Y, Okamoto, Y, Kadowaki, T, Tsukuba, T, Yamamoto, K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] ASSOCIATION OF CATHEPSIN E WITH HOST DEFFENCE A GAINST TUMOR CELLS,(Symposium)2007
- Author(s)
  Kawakubo T, Yasukochi A, Okamoto K, Y Okamoto Y, Kadowaki T, Tsukuba T, Yamamoto K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras,Greece
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンE欠損によるミトコンドリア機能異常と酸化ストレス亢進2007
- Author(s)
  筑波隆幸, 柳川三千代, 岡元邦彰, 門脇知子, 山本健二
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンE欠損はマクロファージの膜蛋白質輸送異常とミトコンドリア機能異常を起こす2007
- Author(s)
  筑波隆幸, 他
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] CONTROL OF THE ENDOSOME/LYSOSOME SYSTEM OF MACR OPHAGES BY CATHEPSIN E2007
- Author(s)
  Tsukuba T, Okamoto K, Kadowaki K, Yamamoto K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras,Greece
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] 血管新生抑制と生体防御能増強によるカテプシンEの腫瘍抑制2007
- Author(s)
  進正史, 門脇知子, 川久保友世, 瀧井良祐, 筑波隆幸, 山本健二
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  宮崎
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E mediates membrane trafficking in macrophages2007
- Author(s)
  Tsukuba T, Yamamoto S, Yanagawa M, Okamoto Y, Okamoto K, Yamamoto K
- Organizer
  第80回日本薬理学会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles for gingipains in atherosclerosis progression accelerated by bacterial exposure2007
- Author(s)
  Kadowaki T, Takii R, Hashimoto M, Yamatake K, Tsukuba T, Yamamoto K
- Organizer
  5TH General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras,Greece
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] エンドソーム系におけるカテプシンEの新たな生理機能と作用機序2007
- Author(s)
  筑波隆幸
- Organizer
  第12回病態と治療におけるプロテアーゼとインヒビター学会(シンポジウム)
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンE欠損はマクロファージの膜蛋白質輸送異常とミトコンドリア機能異常を起こす2007
- Author(s)
  筑波隆幸, 柳川三千代, 岡元邦彰, 岡本美子, 門脇知子, 山本健二
- Organizer
  第30回日本分子生物学会/第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] ベルベリンによる破骨細胞生存の抑制機構の解明2007
- Author(s)
  胡錦萍, 西下一久, 坂井詠子, 岡元邦彰, 筑波隆幸
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] P.gingivalis感染とインスリン抵抗性に関する実験的解析2007
- Author(s)
  門脇知子, 他
- Organizer
  第49回歯科基礎医学会
- Place of Presentation
  札幌・北海道大学
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles for gingipains in atherosclerosis progression accelerated by bacterial exposure2007
- Author(s)
  門脇知子, 他
- Organizer
  5^<th> General Meeting of the Intemational Proteolysis Society
- Place of Presentation
  ギリシア
- Year and Date
  2007-10-23
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] P. gingivalis感染とインスリン抵抗性に関する実験的解析2007
- Author(s)
  門脇知子, 他
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2007-08-31
- Data Source
  KAKENHI-PROJECT-19592148
[Presentation] カテプシンE欠損はマクロファージの膜蛋白質輸送異常とミトコンドリア機能異常を起こす2007
- Author(s)
  筑波隆幸, 他
- Organizer
  第30回日本会子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] P.gingivalis感染とインスリン抵抗性に関する実験的解析2007
- Author(s)
  門脇知子, 他
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2007-08-31
- Data Source
  KAKENHI-PROJECT-19592148
[Presentation] カテプシンE欠損によるミトコンドリア機能異常と酸化ストレス亢進2007
- Author(s)
  筑波隆幸, 他
- Organizer
  第49回歯科基礎医学会
- Place of Presentation
  北海道大学
- Year and Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-19209058
[Presentation] Roles for gingipains in atherosclerosis progression accelerated by bacterial exposure2007
- Author(s)
  Kadowaki T., et.al.
- Organizer
  5^<th> General Meeting of the International Proteolysis Society
- Place of Presentation
  Patras Greece
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-19592148
[Presentation] P.gingivalis感染による生活習慣病増悪に関する基礎的研究2007
- Author(s)
  門脇知子, 瀧井良祐, 重松直樹, 筑波隆幸, 山本健二
- Organizer
  第2回口腔健康科学シンポジウム
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E exerts tumoricidal activity through generation of soluble TRAIL from the tumor cell surface2007
- Author(s)
  Kawakubo T, Kadowaki T, Tsukuba T, Yamamoto K
- Organizer
  第59回日本細胞生物学会大会
- Place of Presentation
  福岡
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] 成熟破骨細胞の延命と脂質ラフト形成におけるリセドロネートおよびD-PDMPの作用2007
- Author(s)
  坂井詠子, 福本敏, 胡錦萍, 西下一久, 佛坂斉祉, 岡元邦彰, 筑波隆幸
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Suppression of carcinogennsis and tumor growth by cathepsin E2006
- Author(s)
  Kawakubo, T, Okamoto, K, Okamoto, Y, Tsukuba, T, Yamamoto, K
- Organizer
  20th IUBMB Congress of Biochemistry and Molecular Biology and FAOBMB Congress
- Place of Presentation
  Kyoto Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles of cathepsin E in immune responses mediated by macrophages.(Symposium)2006
- Author(s)
  Tsukuba, T, Yanagawa, M., Yamamoto S., Kadowaki T., Yamamoto K.
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors, Satellite Meeting of the 20th IUBMB Congress
- Place of Presentation
  Awaji,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] A possible mechanism for cathepsin-E mediated tumor suppression2006
- Author(s)
  Kawakubo T, Okamoto K., Okamoto Y., Tsukuba, T, Yamamoto K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
- Place of Presentation
  Awaji,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E acts as an inhibitor of tumor cells2006
- Author(s)
  Shin, M, Kadowaki, T, Kawakubo, T, Tsukuba, T, Yamamoto, K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
- Place of Presentation
  Awaji, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンEの過剰発現による腫瘍抑制効果2006
- Author(s)
  進正史、門脇知子、川久保友世、筑波隆幸、山本健二
- Organizer
  第59回日本薬理学会西南部会
- Place of Presentation
  那覇
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Suppression of carcinogenesis and tumor growth by cathepsin E2006
- Author(s)
  Kawakubo T, Okamoto K., Okamoto Y., Tsukuba, T, Yamamoto K
- Organizer
  the 20th IUBMB Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congres
- Place of Presentation
  Kyoto Japan.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] A possible mechanism for cathepsin-E mediated tumor suppression2006
- Author(s)
  Kawakubo, T, Okamoto, K, Okamoto, Y, Tsukuba, T, Yamamoto, K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
- Place of Presentation
  Awaii, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Porphyromonas gingivalisの生活習慣病増悪機構について2006
- Author(s)
  門脇知子、筑波隆幸、瀧井良佑、重松直樹、岡元邦彰、山本健二
- Organizer
  第48回歯科基礎医学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Cathepsin E acts as an inhibitor of tumor cells2006
- Author(s)
  Shin M., Kadowaki T., Kawakubo T, Tsukuba, T, Yamamoto K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors
- Place of Presentation
  Awaji,Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] カテプシンE欠損マクロファージにおける膜タンパク質の輸送異常2006
- Author(s)
  筑波隆幸、山本晋也、柳川三千代、岡元邦彰、門脇知子、山本健二
- Organizer
  第48回歯科基礎医学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592038
[Presentation] Roles of cathepsin E in immune responses mediated by macrophages.(Symnosium)2006
- Author(s)
  Tsukuba, T, Yanagawa, M, Yamamoto, S, Kadowaki, T, Yamamoto, K
- Organizer
  The International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors, Satellite Meeting of the 20th IUBMB Congress
- Place of Presentation
  Awaji, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592038

1. TSUKUBA Takayuki (30264055)

# of Collaborated Projects: 21 results

# of Collaborated Products: 229 results
2. YAMAMOTO Kenji (40091326)

# of Collaborated Projects: 10 results

# of Collaborated Products: 77 results
3. OKAMOTO Kuniaki (10311846)

# of Collaborated Projects: 5 results

# of Collaborated Products: 48 results
4. 山口優 (50823308)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
5. NAKAYAMA Koji (80150473)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
6. SATO Keiko (70410579)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
7. 坂井詠子 (10176612)

# of Collaborated Projects: 4 results

# of Collaborated Products: 49 results
8. TAKII Ryosuke (00419558)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
9. YUKITAKE Hideharu (30380984)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
10. 近藤好夫 (30581954)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
11. SHOJI Mikio (10336175)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
12. SASAKI Ken-Ichiro (70320190)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. YOSHIO Katsuki (10389249)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 角忠輝 (80284701)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. KAWAKUBO Tomoyo (70507813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. TOYAMA Yasuyuki (40412506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAITO Mariko (20244072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. KANEKO Satoshi (00342907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HARA Yoshitaka (60159100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. FUJII Yoshito (10404237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Kido Mizuho (60253457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中西博 (20155774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 西下一久 (20237697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
24. 吉本怜子 (70878181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 本田裕子 (60295053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 西山めぐみ (00802844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 鵜飼孝 (20295091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 藤原卓 (00228975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 前田隆浩 (40284674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 大山要 (50437860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 川下由美子 (10304958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 五月女さき子 (20325799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. INOMATA Megumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. INAMITSU Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. EGUCHI Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 吉田教明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 武洲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 村田比呂司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 菊池有一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 青木千春

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KADOWAKI Tomoko 門脇 知子

筑波知子

TSUKUBA Tomoko 筑波 知子

筑波 知子(門脇 知子) ツクバ トモコ（カドワキ トモコ）

筑波 知子(門脇) ツクバ トモコ（カドワキ）

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

コホートを用いた歯周病と全身炎症を繋ぐ分子基盤の解明と病態制御への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanism of mast cell degranulation by the novel Rab proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of chronic inflammation exacerbation mechanism due to breakdown of endo-lysosomal proteolysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

KADOWAKI Tomoko 門脇知子

TSUKUBA Tomoko 筑波知子

筑波知子(門脇知子) ツクバトモコ（カドワキトモコ）

筑波知子(門脇) ツクバトモコ（カドワキ）