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NAGAYAMA Satoshi  長山 聡

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Researcher Number 70362499
Other IDs
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Affiliation (Current) 2022: 京都大学, 医学研究科, 客員研究員
2022: 公益財団法人がん研究会, 有明病院 大腸外科, 医員
Affiliation (based on the past Project Information) *help 2022: 京都大学, 医学研究科, 客員研究員
2022: 公益財団法人がん研究会, 有明病院 大腸外科, 医員
2015 – 2021: 公益財団法人がん研究会, 有明病院 消化器外科, 医長
2017: 公益財団法人がん研究会, 有明病院消化器外科, 医長
2015: 公益財団法人がん研究会, 有明病院消化器外科, 医長 … More
2014 – 2015: 公益財団法人がん研究会, 大腸外科, 医長
2013: 公益財団法人がん研究会, その他部局等, その他
2013: 公益財団法人がん研究会, 有明病院 消化器外科, 医長
2011 – 2012: 公益財団法人がん研究会, 有明病院消化器外科, 医長
2010: Kyoto University, 有明病院消化器外科, 医長
2010: 財団法人癌研究会, 消化器外科, 医長
2007 – 2009: 京都大学, 医学研究科, 助教
2003 – 2006: 京都大学, 医学研究科, 助手
2005: 京都大学, 大学院・医学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Digestive surgery / Tumor biology / Tumor biology / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Basic Section 50010:Tumor biology-related / Digestive surgery / Tumor diagnostics / Basic Section 50020:Tumor diagnostics and therapeutics-related / Experimental pathology / Complex Systems Disease Theory / Basic Section 55010:General surgery and pediatric surgery-related
Keywords
Principal Investigator
大腸癌 / FZD10 / 大腸癌肝転移 / 抗体療法 / 浸潤 / Wnt伝達系 / WNT伝達系 / 大腸癌発生 / 発癌 / 癌幹細胞 … More / 癌細胞株 / 薬剤感受性 / 大腸癌細胞株 / 薬効評価 / プロテオゲノムプロファイリング / 化学療法 / 遺伝子変異 … More
Except Principal Investigator
大腸がん / プロテオミクス / バイオマーカー / 大腸癌 / リン酸化プロテオミクス / 肺がん / リン酸化プロテオーム解析 / エクソソーム / 患者由来オルガノイド / 体細胞変異 / 癌肉腫 / 上皮間葉転換 / 滑膜肉腫 / クローディン / ELF3 / 腫瘍血管新生 / VEGF / RECK / hydrodynamics-based transfection procedure / 血管成熟度 / 遺伝子導入 / 直腸癌局所再発 / 宿主免疫 / NKT細胞 / 遺伝子治療 / CpG配列 / 大腸直腸癌 / hydrodynamics法 / 自然免疫 / Colorectal cancer / Host immune defence / NKT cell / Hydrodynamic method / gene therapy / 癌転移 / 薬効予測 / EGFR阻害剤 / リン酸化タンパク質 / がん / リン酸化タンパク / 薬剤耐性機序 / プロテオミクス解析 / 腫瘍マーカー / 転移早期診断 / 小腸大腸肛門外科学 / 再発早期診断 / KRAS / IFN/STATシグナル / MEK阻害剤 / 家族性大腸腺腫症 / 遺伝学的背景 / 遺伝的背景 / 大腸癌肝転移 / 化学療法耐性 / 生検組織 / がん多様性 / 精密医療 / リン酸プロテオミクス / 転移・再発 / VISIUM / scRNA / 共局在 / クロストーク / シミュレーション / がん微小環境 / モニタリング / メチル化 / dPCR / 再発 / マルチターゲット / ctDNA / リキッドバイオプシー Less
  • Research Projects

    (21 results)
  • Research Products

    (45 results)
  • Co-Researchers

    (38 People)
  •  大腸がん細胞との共局在により悪性度と免疫寛容を獲得するがん微小環境の解明

    • Principal Investigator
      三森 功士
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kyushu University
  •  空間的シングルセル解析による大腸がん転移巣を形成するがん微小環境の解明

    • Principal Investigator
      斉藤 秀幸
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Gunma University
  •  大腸がんの転移・再発における細胞多様性の役割

    • Principal Investigator
      八尾 良司
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  網羅的変異タンパク質定量解析に基づく再発大腸癌の診断、治療法開発

    • Principal Investigator
      植田 幸嗣
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Elucidation of cancer diversity mechanism by analysis of phosphorylation signal using biopsy tissue and application to precision medicine

    • Principal Investigator
      朝長 毅
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  ctDNAメチル化検出を実装する新たなアプローチによる大腸癌再発早期診断法の確立

    • Principal Investigator
      大津 甫
    • Project Period (FY)
      2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Kyushu University
  •  Elucidation of chemoresistance-resistant signal mechanism of colon cancer liver metastasis

    • Principal Investigator
      ADACHI JUN
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Development of a novel therapy for colorectal cancers based on the gene mutation profiles.Principal Investigator

    • Principal Investigator
      Nagayama Satoshi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Genetic- and Somatic-regualtion of colorectal cancer

    • Principal Investigator
      YAO Ryoji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Discovery of drug resistant mechnism by kinome analysis using patient derived cultured cells

    • Principal Investigator
      Tomonaga Takeshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor diagnostics
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Development of a diagnostic model for a risk of colorectal cancer recurrence

    • Principal Investigator
      Ueda Koji
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Complex Systems Disease Theory
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Early diagnosis of colon cancer metastasis by multifaceted proteome analysis of metastatic lesion tissue and exosome

    • Principal Investigator
      Tomonaga Takeshi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Biomarker discovery of colorectal cancer metastasis from cancer tissues and verification in plasma exosomes by targeted proteomics.

    • Principal Investigator
      Shiromizu Takashi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnostics
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Discovery of druggable targets of colorectal cancers by genomic analysis with cancer stem-like cellsPrincipal Investigator

    • Principal Investigator
      Nagayama Satoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Establishment of quantitation method for proteome-based phospho-signaling pathway and its application for prediction of drug effect monitoring

    • Principal Investigator
      Tomonaga Takeshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor diagnostics
    • Research Institution
      National Institutes of Biomedical Innovation, Health and Nutrition
  •  Functinal analysis of a novel gene involved in the progression of colorectal cancersPrincipal Investigator

    • Principal Investigator
      NAGAYAMA satoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  A role of FZD10, a WNT receptor, in the colon carcinogenesis.Principal Investigator

    • Principal Investigator
      NAGAYAMA Satoshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto University
  •  腫瘍血管新生と低酸素環境を標的としたテーラーメード癌治療法の創出

    • Principal Investigator
      MORI Akira
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto University
  •  癌肉腫における上皮間葉二相性組織形成の分子機構

    • Principal Investigator
      TOGUCHIDA Junya
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  大腸癌肝転移巣に対するFZD10を標的分子とした新規抗体療法の開発Principal Investigator

    • Principal Investigator
      長山 聡
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto University
  •  Analysis of cytokine secretion in locally recurrent rectal cancer and host-immune enhancement by gene induction

    • Principal Investigator
      ONODERA Hisashi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2009 2008 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Colorectal Cancer-Derived CAT1-Positive Extracellular Vesicles Alter Nitric Oxide Metabolism in Endothelial Cells and Promote Angiogenesis.2021

    • Author(s)
      Ikeda A, Nagayama S, Sumazaki M, Konishi M, Fujii R, Saichi N, Muraoka S, Saigusa D, Shimada H, Sakai Y, Ueda K
    • Journal Title

      Mol Cancer Res

      Volume: 19 Pages: 834-46

    • DOI

      10.1158/1541-7786.mcr-20-0827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02792
  • [Journal Article] Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer2021

    • Author(s)
      Takuya Okamoto, David duVerle, Katsuyuki Yaginuma, Yasuko Natsume, Hitomi Yamanaka, Daisuke Kusama, Mayuko Fukuda, Mayuko Yamamoto, Yutaka Suzuki, Satoshi Nagayama, Ryoji Yao, et al.
    • Journal Title

      Stem Cell Reports

      Volume: 16 Pages: 954-967

    • DOI

      10.1016/j.stemcr.2021.02.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-18H02684, KAKENHI-PROJECT-18K07217, KAKENHI-PROJECT-19K22570, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21H02770
  • [Journal Article] Evaluation of the RAS signaling network in response to MEK inhibition using organoids derived from a familial adenomatous polyposis patient.2020

    • Author(s)
      Osumi H, Muroi A, Koshikawa N, & Yao R.
    • Journal Title

      Sci Rep.

      Volume: 10 Issue: 1 Pages: 17455-17455

    • DOI

      10.1038/s41598-020-74530-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-18H02684, KAKENHI-PROJECT-19K22570, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329
  • [Journal Article] IFN/STAT signaling controls tumorigenesis and the drug response in colorectal cancer2019

    • Author(s)
      Sakahara Mizuho、Okamoto Takuya、Oyanagi Jun、Takano Hiroshi、Natsume Yasuko、Yamanaka Hitomi、Kusama Daisuke、Fusejima Mishio、Tanaka Norio、Mori Seiich、Kawachi Hiroshi、Ueno Masashi、Sakai Yoshiharu、Noda Tetsuo、Nagayama Satoshi、Yao Ryoji
    • Journal Title

      Cancer Science

      Volume: 110 Pages: 1293-1305

    • DOI

      10.1111/cas.13964

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K14620, KAKENHI-PROJECT-19K22570, KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-18H02684
  • [Journal Article] Improved phosphoproteomic analysis for phosphosignaling and active-kinome profiling in Matrigel-embedded spheroids and patient-derived organoids2018

    • Author(s)
      Abe Yuichi、Tada Asa、Isoyama Junko、Nagayama Satoshi、Yao Ryoji、Adachi Jun、Tomonaga Takeshi
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 11401-11401

    • DOI

      10.1038/s41598-018-29837-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-16H04707, KAKENHI-PROJECT-18H02684, KAKENHI-PROJECT-16H06150, KAKENHI-PROJECT-16K14620, KAKENHI-PROJECT-17K15014
  • [Journal Article] AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers2014

    • Author(s)
      Ryo Takahashi, Satoshi Nagayama, Moritoshi Furu, Yoichiro Kajita, Tomohisa Kato, Seiya Imoto, Yoshiharu Sakai and Junya Toguchida
    • Journal Title

      Cancer Medicine

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-23501276
  • [Journal Article] AFAP1L1, a novel associating partner with vinculin, modulates cellular morphology and motility, and promotes the progression of colorectal cancers2014

    • Author(s)
      Takahashi R, Nagayama S, Furu M, Kajita Y, Jin Y, Kato T, Imoto S, Sakai Y, Toguchida J.
    • Journal Title

      Cancer Med

      Volume: なし Pages: 759-774

    • DOI

      10.1002/cam4.237

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23501276, KAKENHI-PROJECT-24390353, KAKENHI-PROJECT-25670643
  • [Journal Article] Activation of the non-canonical Dvl-Rac1-JNK pathway by Frizzled homologue 10 in human synovial sarcoma2009

    • Author(s)
      Fukukawa C, Nagayama S, Tsunoda T, Toguchida J, Nakamura Y, Katagiri T
    • Journal Title

      Oncogene 28

      Pages: 1110-1120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591589
  • [Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.2009

    • Author(s)
      Nagayama S, et al.
    • Journal Title

      Cancer Sci. 100

      Pages: 405-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591589
  • [Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.2009

    • Author(s)
      Nagayama S, Yamada E, Kohno Y, Aoyama T, Fukukawa C, Kubo H, Watanabe G, Katagiri T, Nakamura Y, Sakai Y, Toguchida J
    • Journal Title

      Cancer Sci 100

      Pages: 405-412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591589
  • [Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors2009

    • Author(s)
      Nagayama S
    • Journal Title

      Cancer Science 100

      Pages: 405-412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591589
  • [Journal Article] Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10.2008

    • Author(s)
      Chikako Fukukawa, Hirofumi Hanaoka, Satoshi Nagayama, Tatsuhiko Tsunoda, Junya Toguchida, Keigo Endo, Yusuke Nakamura, Toyomasa Katagiri
    • Journal Title

      Cancer Sci 99

      Pages: 432-440

    • NAID

      10024002974

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591589
  • [Journal Article] The administration of naked plasmid DNA in to the liver induces antit umor innate immunity in amurine liver metastasis model.2007

    • Author(s)
      Yonenaga Y, Mori A, Fujimoto A, Nagayama S, Tachibana T, Onodera H, Uemoto S
    • Journal Title

      Journal of Gene Medicine 9

      Pages: 299-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591461
  • [Journal Article] Tumour plasticity and extravascular circulation in ECV304 human bladder carcinoma cells.2006

    • Author(s)
      Fujimoto A, Onodera H, Mori A, Nagayama S, Yonenaga Y, Tachibana
    • Journal Title

      Anticancer Research 26

      Pages: 59-69

    • Data Source
      KAKENHI-PROJECT-18591461
  • [Journal Article] Tumour plasticity and extravascular circulation in ECV304 human bladder carcinoma cells2006

    • Author(s)
      Fujimoto A, Onodera H, Mori A, Nagayama S, Yonenaga Y, Tachibana T
    • Journal Title

      Anticancer Res. 26(1A)

      Pages: 59-69

    • Data Source
      KAKENHI-PROJECT-17790912
  • [Journal Article] Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas, and regulated by a member of ets family transcription factor, ELF32006

    • Author(s)
      Yoshiki Kohno, Takeshi Okamoto, Tatsuya Ishibe, Satoshi Nagayama, Yasuko Shima, Kohichi Nishijo, Kohtaro R.Shibata, Koichi Fukiage, Seiji Otsuka, Daisuke Ueshima, Nobuhito Araki, Norifumi Naka, Yasuaki Nakashima, Tomoki Aoyama, Tomitaka Nakayama, Takashi Nakamura, Junya Toguchida
    • Journal Title

      J.Biol.Chem. 281

      Pages: 38941-38950

    • Data Source
      KAKENHI-PROJECT-17790912
  • [Journal Article] Therapeutic potential of antibodies against FZD10, a cell-surface protein, for synovial sarcomas2005

    • Author(s)
      Nagayama, S., et al.
    • Journal Title

      Oncogene 24(15)

      Pages: 6201-6212

    • Data Source
      KAKENHI-PROJECT-17659114
  • [Journal Article] Therapeutic potential of antibodies against FZD10, a cell-surface protein, for synovial sarcomas2005

    • Author(s)
      Nagayama, S., et al.
    • Journal Title

      Oncogene 24

      Pages: 6201-6212

    • Data Source
      KAKENHI-PROJECT-17790912
  • [Presentation] 患者由来大腸がんオルガノイド同所移植マウスモデルにおける転移播種細胞2021

    • Author(s)
      岡本 拓也、柳沼 克幸、長山 聡、小濱 和貴、八尾 良司
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02770
  • [Presentation] 転移に伴う細胞不均一性の変化2021

    • Author(s)
      八尾 良司、長山 聡、岡本 拓也
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02770
  • [Presentation] 患者由来大腸癌オルガノイドを用いた細胞分化プロセスの解析2021

    • Author(s)
      長山 聡、岡本 拓也、八尾 良司
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02770
  • [Presentation] ヒト大腸がん由来オルガノイド移植マウスモデルにおける転移播種がん細胞のEMT解析2021

    • Author(s)
      柳沼 克幸、岡本 拓也、長山 聡、八尾 良司
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02770
  • [Presentation] 患者由来大腸がんオルガノイド同所移植マウスモデルにおける転移播種細胞の同定2020

    • Author(s)
      岡本 拓也、柳沼 克幸、長山 聡、八尾 良司
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02684
  • [Presentation] 大腸癌組織を構成する細胞集団の多様性2020

    • Author(s)
      長山 聡、岡本 拓也、八尾 良司
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02684
  • [Presentation] ヒト大腸がんオルガノイド同所移植マウスモデルにおける転移腫瘍の発生とEMTマーカーの発現2020

    • Author(s)
      柳沼 克幸、岡本 拓也、長山 聡、八尾 良司
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02684
  • [Presentation] 進行大腸がんオルガノイドの1細胞解析2019

    • Author(s)
      八尾 良司、長山 聡、鈴木 穰
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02684
  • [Presentation] 大腸がん同所移植モデルマウスを用いた転移の再現2019

    • Author(s)
      岡本 拓也、柳沼 克幸、長山 聡、八尾 良司
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02684
  • [Presentation] Quantitative proteomic analysis of colorectal cancer liver metastases resistant to postoperative adjuvant chemothrapy.2019

    • Author(s)
      軍司 大悟、阿部雄一、朝長毅、長山聡、足立淳
    • Organizer
      日本プロテオーム学会2019年大会 第70回日本電気泳動学会総会
    • Data Source
      KAKENHI-PROJECT-19H03530
  • [Presentation] BRAF V600E変異陽性大腸がんに有効な既存薬の発見2019

    • Author(s)
      清水 裕貴、きょう 博、大原 智子、長山 聡、藤田 直也、片山 量平
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K07218
  • [Presentation] Development of novel EV-based biomarker for colorectal cancer and its physiological role for angiogenesis2019

    • Author(s)
      Atsushi Ikeda, Satoshi Nagayama, Koji Ueda
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16KT0116
  • [Presentation] 大腸癌発生と薬剤感受性におけるIFN/STATシグナル伝達系の関与2019

    • Author(s)
      長山 聡、岡本 拓也、八尾 良司
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02684
  • [Presentation] Quantitative proteomic profiling of tissue-exudative EVs identified an early diagnostic biomarker protein for colorectal cancer2019

    • Author(s)
      Makoto Konishi, Makoto Sumazaki, Satoshi Muraoka, Atsushi Ikeda, Risa Fujii, Naomi Saichi, Hideaki Shimada, Satoshi Nagayama, Koji Ueda
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16KT0116
  • [Presentation] Identification of a novel diagnostic antigen on circulating exosomes, toward sensitive early detection of colon cancer2018

    • Author(s)
      小西惇、須磨崎真、長山聡、植田幸嗣
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16KT0116
  • [Presentation] Development of liquid biopsy diagnostics for colorectal cancer by proteomic profiling of cultured tissue-derived exosome2018

    • Author(s)
      池田篤志、長山聡、植田幸嗣
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16KT0116
  • [Presentation] 大腸癌切除組織と組織培養分泌エクソソームの網羅的プロテオーム比較分析による大腸癌リキッドバイオプシー診断法開発2017

    • Author(s)
      村岡賢, 大西なおみ, 池田篤志, 須磨崎真, 長山聡, 植田幸嗣
    • Organizer
      日本細胞外小胞学会2017年年会
    • Data Source
      KAKENHI-PROJECT-16KT0116
  • [Presentation] Proteome-wide profiling of viable tissue-derived extracellular vesicles for development of early diagnostic biomarkers for colorectal cancer2017

    • Author(s)
      Muraoka, S., Nagayama, S., and Ueda, K.
    • Organizer
      The International Society For Extracellular Vesicles 6th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0116
  • [Presentation] Targeted proteomic analysis for biomarker discovery of colorectal cancer metastasis from plasma EVs.2016

    • Author(s)
      Takashi Shiromizu, Mimiko Ishida, Naomi Ohnishi, Risa Fujii, Koji Ueda, Satoshi Nagayama and Takeshi Tomonaga.
    • Organizer
      5th Annual Meeting of the International Society for Extracellular Vesicles
    • Place of Presentation
      ロッテルダム
    • Year and Date
      2016-05-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06865
  • [Presentation] 大腸がん同一症例の原発/転移組織の定量プロテオミクス解析による転移マーカー探索および血中エクソソームマーカーへの応用2015

    • Author(s)
      白水崇、長山聡、朝長毅
    • Organizer
      第35回日本分子腫瘍マーカー研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-07
    • Data Source
      KAKENHI-PROJECT-15K06865
  • [Presentation] Proteomic analysis for biomarker discovery in metastatic colorectal cancer tissues and plasma exosomes.2015

    • Author(s)
      Takashi Shiromizu, Satoshi Nagayama, Takeshi Tomonaga
    • Organizer
      第74回 日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K06865
  • [Presentation] 大腸癌臨床組織膜タンパク質および血中エクソソームのプロテオーム解析による転移マーカーの探索2015

    • Author(s)
      白水崇、長山聡、朝長毅
    • Organizer
      第2回日本細胞外小胞学会
    • Place of Presentation
      広島
    • Year and Date
      2015-08-26
    • Data Source
      KAKENHI-PROJECT-15K06865
  • [Presentation] Biomarker discovery of colorectal cancer metastasis from cancer tissues and verification in plasma exosomes by targeted proteomics.2015

    • Author(s)
      Takashi Shiromizu, Satoshi Nagayama, Takeshi Tomonaga
    • Organizer
      第13回日本プロテオーム学会
    • Place of Presentation
      熊本
    • Year and Date
      2015-07-23
    • Data Source
      KAKENHI-PROJECT-15K06865
  • [Presentation] 細胞骨格関連タンパクC7059は細胞形態および細胞遊走を制御し、大著癌進展に関与する2014

    • Author(s)
      長山聡
    • Organizer
      日本外科学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23501276
  • [Presentation] アクチン骨格関連タンパクC7059 は細胞遊走能および浸潤仮足(invadopodia)形成を制御し,大腸癌進展に関与する2013

    • Author(s)
      高橋 亮、長山 聡、布留 守敏、梶田 洋一郎、村上 哲平、加藤 滋、久森 重夫、山田 理大、大越 香江、角田 茂、田中 英治、河田 健二、小濱 和貴、長谷川 傑、岡部 寛、戸口田 淳也、坂井 義治
    • Organizer
      第113回日本外科学会
    • Data Source
      KAKENHI-PROJECT-23501276
  • [Presentation] 細胞骨格関連タンパクC7059 は細胞形態,遊走能および浸潤仮足形成を制御し,大腸癌進展に関与する2013

    • Author(s)
      高橋亮、長山聡、布留守敏、梶田洋一郎、大越香江、山田理大、河田健二、長谷川傑、戸口田淳也、坂井義浩
    • Organizer
      第68回日本消化器外科学会
    • Data Source
      KAKENHI-PROJECT-23501276
  • [Presentation] 細胞骨格関連タンパクC7059 は細胞遊走能を制御して大腸癌進展に関与する2013

    • Author(s)
      長山聡、高橋亮、井元清哉、布留守敏、梶田洋一郎、片桐豊雅、中村祐輔、坂井義治、戸口田淳也
    • Organizer
      第72回日本癌学会
    • Place of Presentation
      (英語口演)
    • Data Source
      KAKENHI-PROJECT-23501276
  • 1.  TOMONAGA Takeshi (80227644)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 7 results
  • 2.  ADACHI JUN (20437255)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 3.  TOGUCHIDA Junya (40273502)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  片山 量平 (60435542)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 5.  新井田 厚司 (00772493)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  三森 功士 (50322748)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  MORI Akira (60324646)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 8.  SAKAI Yoshiharu (60273455)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 9.  Ueda Koji (10509110)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 10.  YAO Ryoji (80291095)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 11.  KUBO Hajime (50362520)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  ONODERA Hisashi (50240825)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  TSURUYAMA Tatsuaki (00303842)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Shiromizu Takashi (00582678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 15.  ISHIHAMA Yasushi (30439244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MATSUBARA Hisahiro (20282486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  波多野 悦朗 (80359801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  小川 晃平 (10359789)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  米永 吉邦 (10422974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  西尾 誠人 (00281593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  藤田 直也 (20280951)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  野村 大成 (90089871)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  朴 成和 (50505948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  佐藤 友美 (10333353)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  丸山 玲緒 (60607985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  小嶋 泰弘 (00881731)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  鈴木 穣 (40323646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 28.  斉藤 秀幸 (10826233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  大津 甫 (50827227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  宇野 直輝 (60624781)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  HOSHINO Daisuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  YAGINUMA Katsuyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  ITOH Takehiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  戸田口 淳也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 8 results
  • 35.  阿部 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  越川 直彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  室井 敦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  加藤 友久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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