SATO Naoyuki 里直行

Researcher Number	70372612
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立長寿医療研究センター, 研究所認知症先進医療開発センター, 副センター長
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人国立長寿医療研究センター, 研究所認知症先進医療開発センター, 副センター長 2020 – 2021: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 副センター長 2018 – 2020: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 部長 2017: 国立研究開発法人国立長寿医療研究センター, その他部局等, 部長 2017: 国立長寿医療研究センター, 認知症先進医療開発センター・分子基盤研究部, 部長 … More 2017: 大阪大学, 医学研究科, 准教授 2016 – 2017: 大阪大学, 医学系研究科, 寄附講座准教授 2016 – 2017: 国立研究開発法人国立長寿医療研究センター, 分子基盤研究部, 部長 2012 – 2016: 大阪大学, 医学(系)研究科(研究院), 准教授 2011 – 2015: 大阪大学, 医学(系)研究科(研究院), 寄附講座准教授 2013: 大阪大学, 医学系研究科, 寄付講座准教授 2012: 大阪大学, 医学系研究科, 准教授 2011: 大阪大学, 医学系・研究科, 寄附講座准教授 2011: 大阪大学, 医学系研究科, 寄附講座准教授 2010: 大阪大学, 医学系研究科, 寄付講座准教授 2010: Osaka University, 大学院・医学系研究科, 寄付講座准教授 2007 – 2009: Osaka University, 医学系研究科, 寄附講座准教授 2004 – 2006: 大阪大学, 医学系研究科, 寄附講座助手 Less
Review Section/Research Field	Principal Investigator General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) / Psychiatric science / Basic Section 52010:General internal medicine-related / Basic Section 52020:Neurology-related / Human genetics Except Principal Investigator General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) / Basic Section 57080:Social dentistry-related / Basic Section 52010:General internal medicine-related / Neurology
Keywords	Principal Investigator アルツハイマー病 / 糖尿病 / 認知症 / βアミロイド / ベータ・アミロイド / タウ / 加齢 / 肥満 / 痴呆 / 遺伝子 … More / 脳科学 / 分子生物学 / 神経科学 / 遺伝子治療 / 老化 / 遺伝子発現 / obesity / diabetes / Alzheimer's disease / 遺伝子型 / グリア / ゲノム編集 / 神経変性 / 糖代謝 / 相互病態修飾 / 神経原線維変化 / 老人斑 / インスリン・シグナル / 恒常性破綻 / タウ・リン酸化 / 病理学 / 離散 / 蛋白輸送 / LRP-1 / クリアランス / アミロイド / ベータ / Aβクリアランス / curcumin / Aβ離散 / 血管 / 肝細胞増殖因子 / 安全性 / 血液・脳関門 / 超音波増強剤 / アストロサイト・グリア系 / 副作用 / 中枢神経系 / 遺伝子導入法 / 肝細胞増殖因 / 中枢性変性疾患 / 超音波 … More Except Principal Investigator アルツハイマー病 / 認知症 / 血管内皮 / Porphyromonas gingivalis / 口腔細菌叢 / 歯周病 / 脳血管障害 / 高血圧 / オートファジー / ベータ・アミロイド / 糖尿病 / インターロイキン-6 / 炎症 / 周辺症状 / 血液脳関門 / βアミロイド / 血管 / 口腔ケア / プロバイオティクス / 行動実験 / 歯周病関連細菌 / BPSD / 16S rRNA菌叢解析 / 血管炎症 / オーラルディアドコキネシス / オーラルフレイル / 口腔機能 / Non-Coding RNA / Non-coding RNA / 関連因子 / 脳脊髄液 / 病理 / 危険因子 / 髄液 / 神経病理 / バイオマーカー / 老年医学 / 高齢者 / ネットワーク / シグナル伝達 / 遺伝子発現 / ＡＤＬ / FAST分類 / 血管障害モデルマウス / ADL / 動物モデル / サルコペニア / 脳血管障害を伴うアルツハイマー病 / FAST / 生活習慣病 / 血管内皮細胞 / 老年病 / ＡＡＡＡＡ / レニン-アンジオテンシン系 / レニンーアンジオテンシン系 / 降圧薬 / AGE受容体 / アンジオテンシンII受容体 / 認知機能 / 脳血管 / サイトカイン / インスリン・シグナリング Less

全身の代謝および老化からみたアルツハイマー病の解析Principal Investigator
- Principal Investigator
  
  里直行
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  National Center for Geriatrics and Gerontology
歯周病菌とアルツハイマー病周辺症状の関連性とその制御に関する総合的研究
- Principal Investigator
  
  松下健二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Ogaki Women's College
  National Center for Geriatrics and Gerontology
Multifaceted analysis of molecular mechanisms by which diabetes and aging are non-genetic risk factors for dementiaPrincipal Investigator
- Principal Investigator
  
  Sato Naoyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  National Center for Geriatrics and Gerontology
The potential of targeting oral microflora and periodontopathogenic bacteria to prevent dementia.
- Principal Investigator
  
  Matsushita Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  National Center for Geriatrics and Gerontology
Research for Alzheimer's disease-related factors based on neuropathological background
- Principal Investigator
  
  Takeya Yasushi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Osaka University
Interactions between diabetes, aging and dementiaPrincipal Investigator
- Principal Investigator
  
  Sato Naoyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  National Center for Geriatrics and Gerontology
Vascular endothelial Non-coding RNA modulates molecular and pathological interaction of hypertension with Alzheimer disease
- Principal Investigator
  
  Hayashi Shinichiro
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Osaka University
  National Cardiovascular Center Research Institute
The development of the clinical course and the animal model of Alzheimer's disease dementia with cerebrovascular disease
- Principal Investigator
  
  Takeya Yasushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Osaka University
Investigation of key molecules involved in bidirectional interactions between diabetes and dementiaPrincipal Investigator
- Principal Investigator
  
  SATO Naoyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  National Center for Geriatrics and Gerontology
  Osaka University
Validation study on insulin resistance occuring in brain of Alzheimer disease
- Principal Investigator
  
  Ikeuchi Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Analysis of the mechanism of homeostatic maintenance against Alzheimer's disease and its failure due to diabetesPrincipal Investigator
- Principal Investigator
  
  SATO Naoyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  National Center for Geriatrics and Gerontology
  Osaka University
Basic research for the clinical application of drugs for a life style disease to treat Alzheimer's disease.
- Principal Investigator
  
  Yamamoto Koichi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Osaka University
Mechanism of vascular endothelial autophagy in metabolic sydrome
- Principal Investigator
  
  Hayashi Shinichiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  National Cardiovascular Center Research Institute
Modification of diabetic phenotype by Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  SATO Naoyuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Osaka University
The roles of insulin signaling between diabetes and Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  SATO Naoyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Osaka University
Phenotypic alterations of brain microvascular endothelium in a model of Alzheimer disease
- Principal Investigator
  
  HAYASHI Shinichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  National Cardiovascular Center Research Institute
Development of a novel therapy for Alzheimer's disease based on vascular modification
- Principal Investigator
  
  MORISHITA Ryuichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Osaka University
Analysis of molecular link between Alzheimer' s disease and diabetes mellitus
- Principal Investigator
  
  MORISHITA Ryuichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Osaka University
Development of therapeutics for dementia targeting Abeta clearancePrincipal Investigator
- Principal Investigator
  
  SATO Naoyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Osaka University
アルツハイマー病ベータ・アミロイド・フィブリルとオリゴマーの解析Principal Investigator
- Principal Investigator
  
  里直行
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Osaka University
アルツハイマー病に対する革新的治療法の開発Principal Investigator
- Principal Investigator
  
  里直行
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Psychiatric science
- Research Institution
  Osaka University
脳への超音波遺伝子導入法の開発と脳変性疾患治療への応用Principal Investigator
- Principal Investigator
  
  里直行
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  Osaka University

[Book] Diabetes Mellitus, A risk factor for Alzheimer's Disease. Eds: Yusaku Nakabeppu & Toshiharu Ninomiya.2019
- Author(s)
  Shinohara M, Sato N
- Total Pages
  17
- Publisher
  Springer Nature Singapore Pte Ltd.
- ISBN
  9789811335396
- Data Source
  KAKENHI-PROJECT-17H04154
[Book] Diabetes Mellitus, A risk factor for Alzheimer's Disease.2019
- Author(s)
  Shinohara M.*　 Sato N.
- Total Pages
  17
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-17H04154
[Book] AβDeposition, Insulin Signaling, and Tau Phosphorylation in Animal Models of Alzheimer Disease and Diabetes.2013
- Author(s)
  Naoyuki Sato and Ryuichi Morishita
- Publisher
  Metabolic Syndrome and Neurological Disorders
- Data Source
  KAKENHI-PROJECT-23390187
[Book] Metabolic Syndrome and Neurological Disorders. Eds: Akhlaq A. Farooqui , Tahira Farooqui.2013
- Author(s)
  Naoyuki Sato and Ryuichi Morishita
- Total Pages
  12
- Publisher
  John Wiley & Sons
- Data Source
  KAKENHI-PROJECT-24659349
[Book] Metabolic Syndrome and Neurological Disorders. Eds: Akhlaq A. Farooqui , Tahira Farooqui2013
- Author(s)
  Naoyuki Sato and Ryuichi Morishita
- Total Pages
  12
- Publisher
  John Wiley & Sons, Inc
- Data Source
  KAKENHI-PROJECT-23390187
[Book] Aβ Deposition, Insulin Signaling, and Tau Phosphorylation in Animal Models of Alzheimer Disease and Diabetes. Metabolic Syndrome and Neurological Disorders2013
- Author(s)
  Naoyuki Sato and Ryuichi Morishita
- Publisher
  Akhlaq A. Farooqui , Tahira Farooqui. John Wiley & Sons
- Data Source
  KAKENHI-PROJECT-24659349
[Journal Article] Autoantibody Profiling Using Human Autoantigen Protein Array and AlphaScreen.2024
- Author(s)
  Takeda H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2766 Issue: 3 Pages: 107-128
- DOI
  10.3390/ijms25031419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08867, KAKENHI-PROJECT-21H02844, KAKENHI-PROJECT-21H03354
[Journal Article] APOE genotypes modify the obesity paradox in dementia2023
- Author(s)
  Shinohara Mitsuru、Gheni Ghupurjan、Hitomi Junichi、Bu Guojun、Sato Naoyuki
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 94 Issue: 9 Pages: 670-680
- DOI
  10.1136/jnnp-2022-331034
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02844, KAKENHI-PROJECT-23K21640
[Journal Article] Effects of APOEε4 genotype on age-associated change in cognitive functions among Japanese middle-aged and older adults: A 20-year follow-up study2023
- Author(s)
  Nishita Yukiko、Sala Giovanni、Shinohara Mitsuru、Tange Chikako、Ando Fujiko、Shimokata Hiroshi、Sato Naoyuki、Otsuka Rei
- Journal Title
  
  Experimental Gerontology
  
  Volume: 171 Pages: 112036-112036
- DOI
  10.1016/j.exger.2022.112036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02844, KAKENHI-PUBLICLY-21H05349
[Journal Article] Relationship Between Plasma Neurofilament Light Chain, Gut Microbiota, and Dementia: A Cross-Sectional Study2022
- Author(s)
  Saji Naoki、Murotani Kenta、Sato Naoyuki、Tsuduki Tsuyoshi、Hisada Takayoshi、Shinohara Mitsuru、Sugimoto Taiki、Niida Shumpei、Toba Kenji、Sakurai Takashi
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 86 Issue: 3 Pages: 1323-1335
- DOI
  10.3233/jad-215141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02844, KAKENHI-PROJECT-20K07861
[Journal Article] Deletion of B-cell translocation gene 2 (BTG2) alters the responses of glial cells in white matter to chronic cerebral hypoperfusion2021
- Author(s)
  Suzuki K, Shinohara M, Uno Y, Tashiro Y, Gheni G, Yamamoto M, Fukumori A, Shindo A, Mashimo T, Tomimoto H, Sato N
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 18 Pages: 86-86
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02844
[Journal Article] ELISA Evaluation of Tau Accumulation in the Brains of Patients with Alzheimer Disease.2021
- Author(s)
  Shinohara M, Hirokawa J, Shimodaira A, Tashiro Y, Suzuki K, Gheni G, Fukumori A, Matsubara T, Morishima M, Saito Y, Murayama S, Sato N
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 80 Pages: 652-662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02844
[Journal Article] Interaction Between APOE Genotype and Diabetes in Longevity2021
- Author(s)
  Shinohara Mitsuru、Suzuki Kaoru、Bu Guojun、Sato Naoyuki
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 82 Issue: 2 Pages: 719-726
- DOI
  10.3233/jad-210125
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02844
[Journal Article] Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes2020
- Author(s)
  Shinohara Mitsuru、Tashiro Yoshitaka、Shinohara Motoko、Hirokawa Junko、Suzuki Kaoru、Onishi‐Takeya Miyuki、Mukouzono Masahiro、Takeda Shuko、Saito Takashi、Fukumori Akio、Saido Takaomi C.、Morishita Ryuichi、Sato Naoyuki
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 2 Pages: 2425-2435
- DOI
  10.1096/fj.201901028rr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04154, KAKENHI-PROJECT-18H02725, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17H05080
[Journal Article] Interaction between APOE genotype and diabetes in cognitive decline2020
- Author(s)
  Shinohara Mitsuru、Tashiro Yoshitaka、Suzuki Kaoru、Fukumori Akio、Bu Guojun、Sato Naoyuki
- Journal Title
  
  Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
  
  Volume: 12 Issue: 1 Pages: 2425-2435
- DOI
  10.1002/dad2.12006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04154, KAKENHI-PROJECT-18H02725, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K10304
[Journal Article] Bidirectional Interaction between Diabetes and Alzheimer's Disease2017
- Author(s)
  Mitsuru Shinohara, Naoyuki Sato
- Journal Title
  
  Neurochemistry International
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293167
[Journal Article] Bidirectional Interaction between Diabetes and Alzheimer's Disease2017
- Author(s)
  Mitsuru Shinohara, Naoyuki Sato
- Journal Title
  
  Neurochemistry International
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15272
[Journal Article] Bidirectional interactions between diabetes and Alzheimer's disease2017
- Author(s)
  Mitsuru Shinohara, Naoyuki Sato
- Journal Title
  
  Neurochemistry International
  
  Volume: 108 Pages: 296-302
- DOI
  10.1016/j.neuint.2017.04.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04154, KAKENHI-PROJECT-15K15272
[Journal Article] The Roles of Lipid and Glucose Metabolism in Modulation of -Amyloid, Tau, and Neurodegeneration in the Pathogenesis of Alzheimer disease2015
- Author(s)
  Naoyuki Sato* and Ryuichi Morishita
- Journal Title
  
  Front. Aging Neurosci.
  
  Volume: 1 Pages: 199-199
- DOI
  10.3389/fnagi.2015.00199
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15272, KAKENHI-PROJECT-26293167
[Journal Article] Brain alterations and clinical symptoms of dementia in diabetes: Aβ/tau-dependent and independent mechanisms.2014
- Author(s)
  Sato N* and Morishita R
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 5 Pages: 143-143
- DOI
  10.3389/fendo.2014.00143
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293167
[Journal Article] Plasma Abeta: A Possible Missing Link Between Alzheimer Disease and Diabetes2013
- Author(s)
  Naoyuki Sato
- Journal Title
  
  DIABETES
  
  Volume: 7 Issue: 4 Pages: 1005-1006
- DOI
  10.2337/db12-1549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145, KAKENHI-PROJECT-23390187, KAKENHI-PROJECT-24659349
[Journal Article] Roles of Vascular and Metabolic Components in Cognitive Dysfunction of Alzheimer disease : Short- and Long-term Modification by Non-genetic Risk Factors2013
- Author(s)
  Sato N and Morishita R
- Journal Title
  
  Front. Aging Neurosci
  
  Volume: 5 Pages: 64-64
- DOI
  10.3389/fnagi.2013.00064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390187, KAKENHI-PROJECT-24659349
[Journal Article] Roles of Vascular and Metabolic Components in Cognitive Dysfunction of Alzheimer disease: Short- and Long-term Modification by Non-genetic Risk Factor2013
- Author(s)
  Sato N* and Morishita R
- Journal Title
  
  Front. Aging Neurosci.
  
  Volume: 5 Pages: 64-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659349
[Journal Article] Increased Blood-Brain Barrier Vulnerability to Systemic Inflammation in Alzheimer Disease Mouse Model.2013
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita.
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 34 Pages: 2064-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659349
[Journal Article] Increased blood-brain barrier vulnerability to systemic inflammation in an Alzheimer disease mouse model2013
- Author(s)
  Takeda S, Sato N(他4名)
- Journal Title
  
  Neurobiol Aging
  
  Volume: vol.34 Pages: 2064-2070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590874
[Journal Article] Increased Blood-Brain Barrier Vulnerability to Systemic Inflammation in Alzheimer Disease Mouse Model2013
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
- Journal Title
  
  Neurobiology of Aging
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-24659349
[Journal Article] Increased Blood-Brain Barrier Vulnerability to Systemic Inflammation in Alzheimer Disease Mouse Model2013
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
- Journal Title
  
  Neurobiology of Aging
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] Increased Blood-Brain Barrier Vulnerability to Systemic Inflammation in Alzheimer Disease Mouse Model.2013
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
- Journal Title
  
  Neurobiology of Aging
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Increased blood-brain barrier vulnerability to systemic inflammation in an Alzheimer disease mouse model2013
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] Phenotypic alterations of brain microvascular endothelium in a murine model of Alzheimer disease2013
- Author(s)
  Hayashi S, Sato N(他2名)
- Journal Title
  
  Stroke
  
  Volume: vol.44(supple)(WOS:000330540200332) Pages: 442-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590874
[Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse2012
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Neuroscience
  
  Volume: 186 Pages: 110-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Oral Glucose Loading Modulates Plasma β-Amyloid Level in Alzheimer's Disease Patients : Potential Diagnostic Method for Alzheimer's Disease.2012
- Author(s)
  Shuko Takeda, et al.
- Journal Title
  
  Dement Geriatr Cogn Disord
  
  Volume: 9;34(1) Issue: 1 Pages: 25-30
- DOI
  10.1159/000338704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05675, KAKENHI-PROJECT-21390222, KAKENHI-PROJECT-22390145, KAKENHI-PROJECT-23390187, KAKENHI-PROJECT-24659349
[Journal Article] Oral Glucose Loading Modulates Plasma Aβ Level in Alzheimer Disease Patients : Potential Diagnostic Method for Alzheimer Disease2012
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Dementia and Geriatric Cognitive Disorders
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Role of Central Nervous System Periostin in Cerebral Ischemia2012
- Author(s)
  Munehisa Shimamura
- Journal Title
  
  Stroke
  
  Volume: 43 Issue: 4 Pages: 1108-1114
- DOI
  10.1161/strokeaha.111.636662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145, KAKENHI-PROJECT-23390187, KAKENHI-PROJECT-24659349
[Journal Article] Dual effects of statins on Abeta metabolism : Up-regulation of degradation of APP-CTF and Abeta clearance2012
- Author(s)
  Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Neurodegenerative diseases
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse2012
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Neuroscience
  
  Volume: 186 Pages: 110-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function2012
- Author(s)
  Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y
- Journal Title
  
  FASEB J
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Dual effects of statins on Abeta metabolism : Up-regulation of degradation of APP-CTF and Abeta clearance2012
- Author(s)
  Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Neurodegenerative diseases
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Role of Central Nervous System Periostin in Cerebral Ischemia2012
- Author(s)
  Shimamura M, Taniyama Y, Katsuragi N, Koibuchi N, Kyutoku M, Sato N, Allahtavakoli M, Wakayama K, Nakagami H, Morishita R
- Journal Title
  
  Stroke
  
  Volume: 43 Pages: 1108-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Oral Glucose Loading Modulates PlasmaAβLevel in Alzheimer DiseasePatients Potential Diagnostic Method for Alzheimer Disease2012
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, and Ryuichi Morishita
- Journal Title
  
  Dementia and GeriatricCognitive Disorders
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Oral Glucose Loading Modulates Plasma Aβ Level in Alzheimer Disease Patients : Potential Diagnostic Method for Alzheimer Disease2012
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Dementia and Geriatric Cognitive Disorders
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] HIG1, a novelregul ator of mitochondrialγ-secretase, ma intains normal mitochondrial function2012
- Author(s)
  Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y
- Journal Title
  
  FASEB J
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Dual effects of statins on Aβ metabolism: upregulation of the degradation of APP-CTF and Aβ clearance2012
- Author(s)
  Sato N
- Journal Title
  
  Neurodegener Dis
  
  Volume: 10 Issue: 1-4 Pages: 305-308
- DOI
  10.1159/000334534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390222, KAKENHI-PROJECT-23390187, KAKENHI-PROJECT-24659349
[Journal Article] Oral Glucose Loading Modulates Plasma Aβ Level in Alzheimer Disease Patients: Potential Diagnostic Method for Alzheimer Disease.2012
- Author(s)
  ShukoTakeda, Naoyuki Sato*, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, and Ryuichi Morishita
- Journal Title
  
  Dementia and Geriatric Cognitive Disorders
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse2012
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
- Journal Title
  
  Neuroscience
  
  Volume: 186 Pages: 110-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Role of Central Nervous System Periostin in Cerebral Ischemia2012
- Author(s)
  Shimamura M, Taniyama Y, Katsuragi N, Koibuchi N, Kyutoku M, Sato N, Allahtavakoli M, Wakayama K, Nakagami H, Morishita R
- Journal Title
  
  Stroke
  
  Volume: 43 Pages: 1108-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function2012
- Author(s)
  Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y. HIG1
- Journal Title
  
  FASEB J
  
  Volume: 26(6) Issue: 6 Pages: 2306-17
- DOI
  10.1096/fj.11-196063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390187, KAKENHI-PROJECT-24659349
[Journal Article] Development of nucleic Acid drugs for neurological disorders2012
- Author(s)
  Shimamura M, Sato N, Nakagami H, Taniyama Y, Morishita R
- Journal Title
  
  Curr Top Med Chem
  
  Volume: 12(15) Pages: 1621-9
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] Differential regulation of amyloid precursor protein/presenilin 1 interaction during Ab40/42 production detected using fusion constructs2012
- Author(s)
  Sato N
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 11 Pages: e48551-e48551
- DOI
  10.1371/journal.pone.0048551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390222, KAKENHI-PROJECT-22591284, KAKENHI-PROJECT-23390187, KAKENHI-PROJECT-23590874, KAKENHI-PROJECT-24659349
[Journal Article] HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function2012
- Author(s)
  Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y
- Journal Title
  
  FASEB J
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Role of Central Nervous System Periostin in Cerebral Ischemia2012
- Author(s)
  Shimamura M, Taniyama Y, Katsuragi N, Koibuchi N, Kyutoku M, Sato N, Allahtavakoli M, Wakayama K, Nakagami H, and Morishita R
- Journal Title
  
  Stroke
  
  Volume: 43 Pages: 1108-1114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Oral Glucose Loading Modulates Plasma Aβ Level in Alzheimer Disease Patients : Potential Diagnostic Method for Alzheimer Disease2012
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Dementia and Geriatric Cognitive Disorders
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Development of nucleic Acid drugs for neurological disorders2012
- Author(s)
  Shimamura M, Sato N, Nakagami H, Taniyama Y, Morishita R.
- Journal Title
  
  Curr Top Med Chem
  
  Volume: 12(15) Pages: 1621-9
- Data Source
  KAKENHI-PROJECT-24659349
[Journal Article] HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function2012
- Author(s)
  Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y
- Journal Title
  
  FASEB J
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] Molecular mechanisms linking diabetes mellitus and Alzheimer disease : beta-amyloid peptide, insulin signaling, and neuronal function2011
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R
- Journal Title
  
  Mol Biosyst
  
  Volume: 7(6) Pages: 1822-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Molecular mechanisms linking diabetes mellitus and Alzheimer disease : beta-amyloid peptide, insulin signaling, and neuronal function2011
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R
- Journal Title
  
  Mol Biosyst
  
  Volume: 7(6) Pages: 1822-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse2011
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Neuroscience
  
  Volume: 186 Pages: 110-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] Experimental and clinical application of plasmid DNA in the field of central nervous diseases2011
- Author(s)
  Shimamura M, Sato N, Morishita R
- Journal Title
  
  Curr Gene Ther
  
  Volume: 11(6) Pages: 491-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Molecular mechanisms linking diabetes mellitus and Alzheimer disease : beta-amyloid peptide, insulin signaling, and neuronal function2011
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R
- Journal Title
  
  Mol Biosyst.
  
  Volume: 7(6) Pages: 1822-1827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Experimental and clinical application of plasmid DNA in the field of central nervous diseases2011
- Author(s)
  Shimamura M, Sato N, Morishita R
- Journal Title
  
  Curr Gene Ther
  
  Volume: 11(6) Pages: 491-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus : a missing link to therapeutic potential.2011
- Author(s)
  Sato N, Takeda S, Uchio-Yamada K, Ueda H, Fujisawa T, Rakugi H, Morishita R.
- Journal Title
  
  Current Aging Science in Press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Experimental and clinical application of plasmid DNA in the field of central nervous diseases2011
- Author(s)
  Shimamura M, Sato N, Morishita R
- Journal Title
  
  Curr Gene Ther.
  
  Volume: 11(6) Pages: 491-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: a missing link to therapeutic potential.2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Tomomi Fujisawa, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Current Aging Science
  
  Volume: 4 Pages: 118-127
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Molecular mechanisms linking diabetes mellitus and Alzheimer disease : beta-amyloid peptide, insulin signaling, and neuronal function2011
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R
- Journal Title
  
  Mol Biosyst
  
  Volume: 7(6) Pages: 1822-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Experimental and clinical application of plasmid DNA in the field of central nervous diseases2011
- Author(s)
  Shimamura M, Sato N, Morishita R
- Journal Title
  
  Curr Gene Ther
  
  Volume: 11(6) Pages: 491-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse.2011
- Author(s)
  Shuko Takeda, Naoyuki Sato*, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
- Journal Title
  
  Neuroscience
  
  Volume: 186 Pages: 110-9
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse with diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Proceeding of National Academy of Sciences of United States of America
  
  Volume: 107 Pages: 7036-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Reduction of Brain β-amyloid (Aβ) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, thrpugh increase in degradation of amyloid precursor protein C-terminal fragnents (APP-CTFs) and Aβ clearance2010
- Author(s)
  Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 285 Pages: 22091-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Plasma β-amyloid as potential biomarker of Alzheimer disease : possibility of diagnostic tool for Alzheimer disease2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Journal Title
  
  Molecular BioSystems
  
  Volume: 6 Pages: 1760-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Ass deposition in an Alzheimer mouse model with diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Proceedings of National Academy of Sciences of United States of America (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Reduction of Brain β-amyloid (Aβ) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, thrpugh increase in degradation of amyloid precursor protein C-terminal fragnents (APP-CTFs) and Aβ clearance2010
- Author(s)
  Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 285 Pages: 22091-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus : a missing link to therapeutic potential.2010
- Author(s)
  Sato N, Takeda S, Uchio-Yamada K, Ueda H, Fujisawa T, Rakugi H, Morishita R.
- Journal Title
  
  Current Aging Science
  
  Volume: (In Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Animal Models of Alzheimer Disease for Translational Research: Current and Future Concepts. Horizons in Neuroscience Research. Volume 4 (Hardcover)2010
- Author(s)
  Shuko Takeda, Naoyuki Sato, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse with diabetes.2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Proceeding of National Academy of Sciences of United States of America 107
  
  Pages: 7036-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus : a missing link to therapeutic potential.2010
- Author(s)
  Sato N, Takeda S, Uchio-Yamada K, Ueda H, Fujisawa T, Rakugi H, Morishita R.
- Journal Title
  
  Current Aging Science
  
  Volume: (In Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus : a missing link to therapeutic potential.2010
- Author(s)
  Sato N, Takeda S, Uchio-Yamada K, Ueda H, Fujisawa T, Rakugi H, Morishita R.
- Journal Title
  
  Current Aging Science
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse model with diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Proceedings of National Academy of Sciences of United States of America. (In press.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Reduction of brain A. by fluvastatin, an HMG-CoA reductase inhibitor, through increase in degradation of APP-CTFs and A. clearance.2010
- Author(s)
  Mitsuru Shinohara, Naoyuki Sato, Hitomi Kurinami, Daisuke Takeuchi, Shuko Takeda, Munehisa Shimamura, Toshihide Yamashita, Yasuo Uchiyama, Hiromi Rakugi, and Ryuichi Morishita
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 285 Pages: 22091-22102
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Plasma Beta-Amyloid as Potential Biomarker of Alzheimer Disease: Possibility of Diagnostic Tool of Alzheimer Disease.2010
- Author(s)
  Shuko Takeda, Naoyuki Sato, Hiromi Rakugi, and Ryuichi Morishita
- Journal Title
  
  Molecular BioSystems
  
  Volume: 6 Pages: 1760-1766
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Diabetes accelerated memory dysfunction via cerebrovascular inflammation and A. deposition in an Alzheimer mouse model with diabetes.2010
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru Shinohara, Hiromi Rakugi, and Ryuichi Morishita
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 13, 107 Pages: 7036-41
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse with diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Proceeding of National Academy of Sciences of United States of America
  
  Volume: 107 Pages: 7036-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Plasma β-amyloid as potential biomarker of Alzheimer disease : possibility of diagnostic tool for Alzheimer disease2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Journal Title
  
  Molecular BioSystems
  
  Volume: 6 Pages: 1760-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Reduction of Brain β-amyloid (Aβ) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, thrpugh increase in degradation of amyloid precursor protein C-terminal fragnents (APP-CTFs) and Aβ clearance2010
- Author(s)
  Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 285 Pages: 22091-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Plasma β-amyloid as potential biomarker of Alzheimer disease : possibility of diagnostic tool for Alzheimer disease2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Journal Title
  
  Molecular BioSystems
  
  Volume: 6 Pages: 1760-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Plasma β-amyloid as potential biomarker of Alzheimer disease : possibility of diagnostic tool for Alzheimer disease.2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Journal Title
  
  Molecular BioSystems 6
  
  Pages: 1760-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse with diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Proceeding of National Academy of Sciences of United States of America
  
  Volume: 107 Pages: 7036-7041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Reduction of Brain β-amyloid (Aβ) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, thrpugh increase in degradation of amyloid precursor protein C-terminal fragnents (APP-CTFs) and Aβ clearance.2010
- Author(s)
  Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R.
- Journal Title
  
  The Journal of Biological Chemistry 285
  
  Pages: 22091-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Alzheimer disease-associated peptide, amyloid beta40, inhibits vascular regeneration with induction of endothelial autophagy2009
- Author(s)
  Hayashi S, Sato N, Yamamoto A, Ikegame Y, Nakashima S, Ogihara T, Morishita R.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 29
  
  Pages: 1909-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Angiotensin receptor blocker prevented beta-amyloid-induced cognitive impairment associated with recovery of neurovascular coupling2009
- Author(s)
  Takeda S, Sato N, Takeuchi D, Kurinami H, Shinohara M, Niisato Kano M, Ogihara T, Rakugi H, Morishita R.
- Journal Title
  
  Hypertension 54
  
  Pages: 1345-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Alzheimer disease-associated peptide, amyloid beta40, inhibits vascular regeneration with induction of endothelial autophagy.2009
- Author(s)
  Hayashi S, Sato N, Yamamoto A, Ikegame Y, Nakashima S, Ogihara T, Morishita. R.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 29(説明:スライド1)
  
  Pages: 1909-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Angiotensin receptor blocker prevented beta-amyloid-induced cognitive impairment associated with recovery of neurovascular coupling2009
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Biochem Biophys Res Commun 385
  
  Pages: 193-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Angiotensin Receptor Blocker Prevented b-Amyloid-Induced Cognitive Impairment Associated With Recovery of Neurovascular Coupling2009
- Author(s)
  Shuko Takeda, Naoyuki Sato, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru S hinohara, Kazue, Niisato, Masanobu Kano, Toshio Ogihara, Hiromi Rakugi and Ryuichi Morishita
- Journal Title
  
  Hypertension
  
  Volume: 54 Pages: 1345-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Elevation of Plasma β-amyloid level by Glucose Loading in Alzheimer Mouse Models.2009
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Biochemical and Biophysical Research Communications 385
  
  Pages: 193-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Validation of Abetal-40 administration into mouse cerebroventricles as an animal model for Alzheimer disease2009
- Author(s)
  Takeda S, Sato N, Niisato K, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Kano M, Morishita R.
- Journal Title
  
  Brain Res. 1280
  
  Pages: 137-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Angiotensin receptor blocker prevented beta-amyloid-induced cogniti impairment associated with recovery of neurovascular coupling.2009
- Author(s)
  Takeda S, Sato N, Takeuchi D, Kurinami H, Shinohara M, Niisato Kano M, Ogihara T, Rakugi H, Morishita R.
- Journal Title
  
  Hypertension. 54
  
  Pages: 1345-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Validation of Abetal-40 administration into mouse cerebroventricles as an animal model for Alzheimer disease.2009
- Author(s)
  Takeda S, Sato N, Niisato K, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Kano M, Morishita R.
- Journal Title
  
  Brain Res. 1280
  
  Pages: 137-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Alzheimer disease-associated peptide, amyloid beta4O, inhibits vascular regeneration with induction of endothelial autophagy.2009
- Author(s)
  Hayashi S, Sato N, Yamamoto A, lkegame Y, Nakashima S, Ogihara T, Morishita R.
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 29
  
  Pages: 1909-1915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Ryuichi Morishita, Validation of Aβ1-40 administration into mouse cerebroventricles as an animal model for Alzheimer disease2009
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kazue Niisato, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru Shinohara, Hiromi Rakugi, Masanobu Kano
- Journal Title
  
  Brain Res
  
  Volume: 1280 Pages: 137-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Angiotensin receptor blocker prevented beta-amyloid-induced cogniti impairment associated with recovery of neurovascular coupling.2009
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
- Journal Title
  
  Biochem Biophys Res Commun. 385
  
  Pages: 193-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659179
[Journal Article] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Cognitive Impairment Associated with Recovery of Neurovascular Coupling.2009
- Author(s)
  Takeda S, Sato N, Takeuchi D, Kurinami H, Shinohara M, Niisato K, Kano M, Ogihara T, Rakugi H, Morishita R.
- Journal Title
  
  Hypertension 54
  
  Pages: 1345-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Validation of Aβ1-40 Administration into Mouse Cerebroventricles as an Animal Model for Alzheimer Disease.2009
- Author(s)
  Takeda S, Sato N, Niisato K, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Kano M, Morishita R.
- Journal Title
  
  Brain Research 1280
  
  Pages: 137-147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Prevention of dementia by antihypertensive drugs : how AT1-receptor-blockers and dihydropyridines better prevent dementia in hypertensive patients and ACE-inhibitors.2009
- Author(s)
  Fournier A, Oprisiu-Fournier R, Serot JM, Godefroy O, Achard JM, Faure S, Mazouz H, Temmar M, Albu A, Bordet R, Hanon O, Gueyffier F, Wang J, Black S, Sato N.
- Journal Title
  
  Expert Rev Neurother 9(9)
  
  Pages: 1413-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] A model of cerebrovascular injury in rats.2008
- Author(s)
  Wakayama K, Shimamura M, Sata M, koibuchi N, Sato N, Ogihara T, Morishita R.
- Journal Title
  
  Neurosci Methods 175
  
  Pages: 187-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Prevention of amyloid β-induced memory impairment by fluvastatin, associated with the decrease in amyloid β accumulation and oxidative stress in amyloid β injection mouse model.2008
- Author(s)
  Kurinami H, Sato N, Shinohara M, Takeuchi D, Takeda S, Shimamura M, Ogihara T and Morishita R.
- Journal Title
  
  International Journal of Molecular Medicine (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Alleviation of Aβ-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model.2008
- Author(s)
  Takeuchi D, Sato N, Shimamura M, Kurinami H, Takeda S, Shinohara M, Suzuki S, Kojima M, Ogihara T, Morishita R.
- Journal Title
  
  Gene Therapy 15
  
  Pages: 561-571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Prevention of amyloid beta-induced memory impairment by fluvastatin, associated with the decrease in amyloid beta accumulation and oxidative stress in amyloid beta injection mouse model.2008
- Author(s)
  Kurinami H, Sato N, Shinohara M, Takeuchi D, Takeda S, Shimamura M, Ogihara T, Morishita R.
- Journal Title
  
  Gene Therapy 15
  
  Pages: 561-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Alleviation of Aβ-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model.2008
- Author(s)
  TakeucM D, Sato N, Shimamura M, Kurinami H, Takeda S, Shinohara M, Suzuki S, Kojima M, Ogihara T and Morishita R.
- Journal Title
  
  Gene Therapy in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] The Renin-Angiotensin System, Hypertension and cognitive dysfunction in Alzheimer's Disease: New Therapeutic Potential.2008
- Author(s)
  Takeda S, Sato N, Morishita R
- Journal Title
  
  Frontiers in Bioscience 13
  
  Pages: 2253-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Prevention of amyloid P-induced memory impairment by fluvastatin, associated with the decrease in amyloid βaccumulation and oxidative stress in amyloid βinjection mouse model.2008
- Author(s)
  Kurinami H, Sato N, Shino hara M, Takeuchi D, Takeda S, Shimamura M, Ogihara T, Morishita R.
- Journal Title
  
  International Journal of Molecular Medicine 21
  
  Pages: 531-537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] The Renin-Angiotensin System, Hypertension and cognitive dysfunction in Alzheimer's Disease: New Therapeutic Potential.2008
- Author(s)
  Takeda S, Sato N, Morishita R
- Journal Title
  
  Frontiers in Bioscience 13
  
  Pages: 2253-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Prevention of amyloid β-induced memory impairment by fluvastatin, associated with the decrease in amyloid β accumulation and oxidative stress inamyloid βinjection mouse model.2008
- Author(s)
  Kurinami H, Sato N, Shinohara M, Takeuchi D, Takeda S, Shimamura M, Ogihara T and Morishita R.
- Journal Title
  
  International Journal of Molecular Medicine in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Alleviation of Aβ-induced cognitive impairment by ultrasound-mediated gene transfer of HGF in a mouse model.2008
- Author(s)
  Takeuchi D, Sato N, Shimamura M, Kurinami H, Takeda S, Shinohara M, Suzuki S, Kojima M, Ogihara T and Morishita R.
- Journal Title
  
  Gene Therapy (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] A model of cerebrovascular injury in rats.2008
- Author(s)
  Wakayama K, Shimamura M, Sata M, Koibuchi N, Sato N, Ogihara T, Morishita R
- Journal Title
  
  J Neurosci Methods 175
  
  Pages: 187-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] The Renin-Antagotensin system, Hypertension and cognitive dysfunction in Alzheimer's Disease : New Therapeutic Potential.2008
- Author(s)
  Takeda S, Sato N, Ogihara T, Morishita R.
- Journal Title
  
  Frontiers in Bioscience 13
  
  Pages: 2253-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590697
[Journal Article] Involvement of gamma-secretase in postnatal angiogenesis.2007
- Author(s)
  Hayashi H, Nakagami H, Takami Y, Sato N, Saitoh Y, Nishikawa T, Mori M, Koriyama H, Tamai K, Morishita R, Kaneda Y.
- Journal Title
  
  Biochem. Biophys. Res. Conunun. 363
  
  Pages: 584-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Delayed Post-ischemic Treatment with Fluvastatin Improved Learning and Memory Deficit After Stroke in Rats.2007
- Author(s)
  Shimamura M, Sato N, Sata, M, Kurinami, H, Takeuchi, D, Wakayama, K, Hayashi, T, Iida, H, Mori shita R.
- Journal Title
  
  Stroke 38
  
  Pages: 3251-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Expression of hepatocyte growth factor and c-Met after spinal cord injury in rats.2007
- Author(s)
  Shimamura M, Sato N, Sata M, Wakayama K, 0gihara T, Morishita R.
- Journal Title
  
  Brain Res. 1151
  
  Pages: 188-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Involvement of gamma-secretase in postnatal angiogenesis.2007
- Author(s)
  Hayashi H, Nakagami H, Takami Y, Sato N, Saitoh Y, Nishikawa T, Mori M, Koriyama H, Tamai K, Morishita R, Kaneda Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 363
  
  Pages: 584-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Quantitative measurement of neurological deficit after mild (30 min) transient middle cerebral artery occlusion in rats.2007
- Author(s)
  Wakayama K, Shimamura M, Sata M, Sato N, Kawakami K, Fukuda H, Tomimatsu T, Ogihara T, Morishita R
- Journal Title
  
  Brain Res. 1130号
  
  Pages: 181-187
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Expression of hepatocyte growth factor and c-Met after spinal cord injury in rats.2007
- Author(s)
  Shimamura M, Sato N, Sata M, Wakayama K, Ogihara T, Morishita R.
- Journal Title
  
  Brain Res. 1151
  
  Pages: 188-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Quantitative measurement of neurological deficit after mild (30 min) transient middle cerebral artery occlusion in rats.2007
- Author(s)
  Wakayama K, Shimamura M, Sata M, Sato N, Kawakami K, Fukuda H, Tomimatsu T, Ogihara T, Morishita R
- Journal Title
  
  Brain Res. 1130号
  
  Pages: 181-187
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Delayed Post-ischemic Treatment with Fluvastatin Improved Learning and Memory Deficit After Stroke in Rats.2007
- Author(s)
  Shimamura M, Sato N, Sata, M, Kurinami, H, Takeuchi, D, Wakayama, K, Hayashi, T, Iida, H, Morishita R.
- Journal Title
  
  Stroke 38
  
  Pages: 3251-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Development of new screening system for Alzheimer Disease, in vitro Aβ sink assay, to identify the dissociation of soluble Aβ from fibrils.2006
- Author(s)
  Sato N, Okochi M, Taniyama Y, Kurinami H, Shimamura M, Takeuchi D, Hamada H, Fukumori A, Kiyosue K, Taguchi T, Tanaka T, Miyasaka M, Takeda M, Ogihara T, Morishita R
- Journal Title
  
  Neuobiology of Disease 22
  
  Pages: 487-495
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Gene Transfer of Hepatocyte Growth Factor Gene Improves Learning and Memory in the Chronic Stage of Cerebral Infarction.2006
- Author(s)
  Shimamura M, Sato N, Waguri S, Uchiyama Y, Hayashi T, Iida H, Nakamura T, Ogihara T, Kaneda Y, Morishita M
- Journal Title
  
  Hypertension 47
  
  Pages: 742-751
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Development of new screening system for Alzheimer Disease, in vitro Aβ sink assay, to identify the dissociation of soluble Aβ from fibrils.2006
- Author(s)
  Sato N, Okochi M, Taniyama Y, Kurinami H, Shimamura M, Takeuchi D, Hamada H, Fukumori A, Kiyosue K, Taguchi T, Tanaka T, Miyasaka M, Takeda M, Ogihara T, Morishita R
- Journal Title
  
  Neuobiology of Disease 22
  
  Pages: 487-495
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Gene Transfer of Hepatocyte Growth Factor Gene Improves Learning and Memory in the Chronic Stage of Cerebral Infarction.2006
- Author(s)
  Shimamura M, Sato N, Waguri S, Uchiyama Y, Hayashi T, Iida H, Nakamura T, Ogihara T, Kaneda Y, Morishita M
- Journal Title
  
  Hypertension 47
  
  Pages: 742-751
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Recent Progress in Cerebrovascular Gene Therapy2005
- Author(s)
  Sato N, Shimamura M, Morishita R.
- Journal Title
  
  Current Neurovascular Research. 2・3
  
  Pages: 235-247
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Recent Progress in Cerebrovascular Gene Therapy2005
- Author(s)
  Sato N, Shimamura M, Morishita R.
- Journal Title
  
  Current Neurovascular Research. 2・3
  
  Pages: 235-247
- Data Source
  KAKENHI-PROJECT-16659089
[Journal Article] Development of new screening system for Alzheimer Disease, in vitro Aβ sink assay, to identity the dissociation of soluble Aβ from fibrils.
- Author(s)
  Sato N, Okochi M, Taniyama Y, Kurinami H, Shimamura M, Takeuchi D, Hamada H, Fukumori A, Kiyosue K, Taguchi T, Tanaka T, Miyasaka M, Takeda M, Ogihara t, Morishita R.
- Journal Title
  
  Neuobiology of Disease (in press)
- Data Source
  KAKENHI-PROJECT-16659089
[Journal Article] Gene Therapy for Ischemic Brain Disease with special reference to Vascular Dementia.
- Author(s)
  Sato N, Shimamura M, Takeuchi D, Kurinami H, Ogihara T, Morishita R
- Journal Title
  
  Geriatrics and Gerontology International (in press)
- NAID
  10019489400
- Data Source
  KAKENHI-PROJECT-18659334
[Journal Article] Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles.
- Author(s)
  Shimamura, M., Sato, N., Taniyama, Y., Kurinami, H., Tanaka, H., Takami, T., Ogihara, T., Tohyama, M., Kaneda, Y., Morishita, R.
- Journal Title
  
  J.Gene Med (in press)
- Data Source
  KAKENHI-PROJECT-16659089
[Journal Article] Gene Therapy for Ischemic Brain Disease with special reference to Vascular Dementia.
- Author(s)
  Sato N, Shimamura M, Takeuchi D, Kurinami H, Ogihara T, Morishita R
- Journal Title
  
  Geriatrics and Gerontology International in press
- NAID
  10019489400
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Differential Regulation of Amyloid Precursor Protein /Presenilin 1 Interaction during Aβ40/42 Production Detected Using Fusion Constructs.
- Author(s)
  Naoyuki Sato, Masayasu Okochi, Mitsuru Shinohara, Gopal Thinakaran, Shuko Takeda, Akio Fukumori, Motoko Shinohara-Noma, Mari Mori-Ueda, Hizuki Hamada, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  PLoS ONE
  
  Volume: 7(11)
- Data Source
  KAKENHI-PROJECT-22390145
[Journal Article] Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles.
- Author(s)
  Shimamura, M., Sato, N., Taniyama, Y., Kurinami, H., Tanaka, H., Takami, T., Ogihara, T., Tohyama, M., Kaneda, Y., Morishita, R.
- Journal Title
  
  J.Gene Med (in press)
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Possible Modification of Alzheimer Disease by Statins in Midlife : Interactions with Genetic and Non-Genetic Risk Factors
- Author(s)
  Mitsuru Shinohara, Naoyuki Sato, Munehisa Shimamura, Hitomi Kurinami, Toshimitsu Hamasaki, Amarnath Chatterjee, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Front. Aging Neurosci
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-23390187
[Journal Article] Development of new screening system for Alzheimer Disease, in vitro Aβ sink assay, to identify the dissociation of soluble Aβ from fibrils.
- Author(s)
  Sato N, Okochi M, Taniyama Y, Kurinami H, Shimamura M, Takeuchi D, Hamada H, Fukumori A, Kiyosue K, Taguchi T, Tanaka T, Miyasaka M, Takeda M, Ogihara T, Morishita R.
- Journal Title
  
  Neuobiology of Disease. (in press)
- Data Source
  KAKENHI-PROJECT-17689034
[Journal Article] Possible Modification of Alzheimer Disease by Statins in Midlife : Interactions with Genetic and Non-Genetic Risk Factors
- Author(s)
  Mitsuru Shinohara, Naoyuki Sato, Munehisa Shimamura, Hitomi Kurinami, Toshimitsu Hamasaki, Amarnath Chatterjee, Hiromi Rakugi, Ryuichi Morishita
- Journal Title
  
  Front Aging Neurosci
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-24659349
[Patent] 透析プローブ2010
- Inventor(s)
  武田朱公、里直行、森下竜一、西野博仁、生村和子
- Industrial Property Rights Holder
  大阪大学、株式会社エイコム
- Acquisition Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20590697
[Patent] 透析プローブ2010
- Inventor(s)
  武田朱公、里直行、森下竜一、西野博仁、生村和子
- Industrial Property Rights Holder
  大阪大学、株式会社エイコム
- Acquisition Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22390145
[Patent] 透析プローブ2010
- Inventor(s)
  武田朱公、里直行、森下竜一、西野博仁、生村和子
- Industrial Property Rights Holder
  大阪大学、株式会社エイコム
- Acquisition Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21659179
[Patent] 新規マイクロダイアライシス回路を用いた脳内物質の精密測定法2010
- Inventor(s)
  西野博仁、生村和子、武田朱公,里直行,森下竜一
- Filing Date
  2010-04-26
- Data Source
  KAKENHI-PROJECT-22390145
[Patent] 透析プローブ2010
- Inventor(s)
  武田朱公、里直行、森下竜一、西野博仁、生村和子
- Industrial Property Rights Holder
  大阪大学、株式会社エイコム
- Acquisition Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21659179
[Patent] アルツハイマー病の新規診断方法の発明2009
- Inventor(s)
  武田朱公, 里直行, 内尾こずえ, 森下竜一
- Industrial Property Rights Holder
  大阪大学, 医薬基盤研究所
- Filing Date
  2009-02-13
- Data Source
  KAKENHI-PROJECT-20590697
[Patent] Remedy for Alzheimers disease2007
- Inventor(s)
  里直行、林真一郎、竹内大亮、森下竜一
- Industrial Property Rights Holder
  大阪大学、アンジェス MG
- Filing Date
  2007-05-24
- Overseas
- Data Source
  KAKENHI-PROJECT-17689034
[Patent] Remedy for Alzhei mer's disease2007
- Inventor(s)
  里直行、林真一郎、竹内大亮、森下竜一
- Industrial Property Rights Holder
  大阪大学、アンジェスMG
- Filing Date
  2007-05-24
- Overseas
- Data Source
  KAKENHI-PROJECT-18659334
[Presentation] 慢性脳低灌流はタウの蓄積伝播を抑制する2023
- Author(s)
  武倉アブドグプル,篠原充,鈴掛雅美,新堂晃大,渡邉淳,富本秀和,長谷川成人,里直行
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] INTERACTION BETWEEN APOE GENOTYPE AND DIABETES IN LONGEVITY AND DEMENTIA2023
- Author(s)
  Naoyuki Sato
- Organizer
  AD/PD 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] Effects of chronic cerebral hypoperfusion on tau propagation2023
- Author(s)
  Ghupurjan Gheni,Mitsuru Shinohara,Masami Masuda Suzukake,Akihiko Shindo,Hidekazu Tomimoto,Atsushi Watanabe,Masato Hasegawa,Naoyuki Sato
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] INTERACTION BETWEEN APOE GENOTYPE AND DIABETES IN LONGEVITY AND DEMENTIA2023
- Author(s)
  Naoyuki Sato
- Organizer
  Cancer Research UK Cambridge Institute
- Invited
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] ApoEと受容体の結合を阻害する薬剤の検討2023
- Author(s)
  篠原充,武倉アブドグプル,里直行
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] Clinical stroke is associated with fewer Alzheimer’s and Lewy body pathologies2023
- Author(s)
  Mitsuru Shinohara,Ghupurjan Gheni,Guojun Bu,Naoyuki Sato
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] APOE多型と肥満の認知機能への交互作用の検討2022
- Author(s)
  篠原充、武倉アブドグプル、人見　淳一、Guojun Bu、里　直行
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] 認知症における肥満パラドックスとそのメカニズムの解明2022
- Author(s)
  里　直行
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] ごく微量のAβ42の増加でも、肥満糖尿病と加齢下では脳の遺伝子発現に大きく影響する2022
- Author(s)
  篠原充,　Ioana Olan,　武倉アブドグプル,　斉藤貴志,　西道隆臣,　成田匡志,　里直行
- Organizer
  第64回日本老年医学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] DSタウを用いたタウ伝播における慢性脳低灌流の影響の解明2022
- Author(s)
  武倉　アブドグプル、鈴掛　雅美、篠原　充、渡邉　淳、新堂　晃大、冨本秀和、長谷川　成人、里　直行
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] ごく微量のAβ42の増加でも、肥満糖尿病と加齢下では脳の遺伝子発現に大きく影響する2022
- Author(s)
  篠原充、Ioana Olan、武倉アブドグプル、斉藤　貴志、西道　隆臣、成田匡志、里　直行
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] タンパク質蓄積病態に影響するファクターとは2021
- Author(s)
  里直行
- Organizer
  第40回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] 家族性変異PSENにも効果のあるγセクレターゼモジュレーターの探索2021
- Author(s)
  篠原充,　福森亮雄,　里直行
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] B-cell translocation gene 2 (BTG2)欠損による慢性脳低灌流およびin vitroでのグリア細胞動態変化2021
- Author(s)
  鈴木香,　篠原充,　夘野善弘,　田代善崇,　吾甫江艾尼,　山本美帆,　福森亮雄,　新堂晃大,　真下知士 ,　冨本秀和,　里直行
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] APOE多型と糖尿病の寿命への交互作用の検討2021
- Author(s)
  篠原充,　鈴木香,　Bu Guojun,　里直行
- Organizer
  第63回日本老年医学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] 糖尿病による認知機能障害の機序_臨床データベースとモデル動物の解析から2021
- Author(s)
  里直行
- Organizer
  第63回日本老年医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02844
[Presentation] Bidirectional interactions between obesity/diabetes and Alzheimer's disease2020
- Author(s)
  Naoyuki Sato
- Organizer
  The 15th International Symposium on Geriatrics and Gerontology
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] Bidirectional interactions between obesity/diabetes and Alzheimer's disease.2019
- Author(s)
  Naoyuki Sato
- Organizer
  Molecular Mechanisms and Therapeutic Opportunities in Alzheimer's Disease
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] 糖尿病による認知症・アルツハイマー病促進のメカニズム2019
- Author(s)
  里　直行
- Organizer
  第116回日本内科学会総会・講演会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] アルツハイマー病の基礎研究2019
- Author(s)
  里　直行
- Organizer
  第13回老年医学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] 神経変性を予測する血液バイオマーカーとしてのNeurofilament light(NFL)概説2019
- Author(s)
  里　直行
- Organizer
  第9回日本認知症予防学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] 糖尿病と認知症の基礎研究の最近の進歩2019
- Author(s)
  里　直行
- Organizer
  第34回日本糖尿病合併症学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] 糖尿病とアルツハイマー病の悪循環の分子機構2018
- Author(s)
  里　直行
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] Bidirectional interactions between diabetes and Alzheimer's disease2018
- Author(s)
  Naoyuki Sato
- Organizer
  The 4th ICAH-NCGG Symposium
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] Bidirectional interaction between diabetes and Alzheimer’s disease2018
- Author(s)
  里　直行
- Organizer
  第10回NAGOYAグローバルリトリート招待講演
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] 糖尿病および加齢による認知症促進機構に着目した次世代の認知症創薬を目指して2018
- Author(s)
  里直行
- Organizer
  3）第24回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] Bidirectional Interactions between Diabetes and Alzheimer's Disease2018
- Author(s)
  Naoyuki Sato
- Organizer
  1）The 14th International Symposium on Geriatrics and Gerontology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] Bidirectional interaction between diabetes and Alzheimer’s disease2018
- Author(s)
  里　直行
- Organizer
  第10回NAGOYAグローバルリトリート招待講演
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病による認知症促進機構の解明2017
- Author(s)
  里　直行
- Organizer
  第36回日本認知症学会学術集会シンポジウム18【生活習慣・生活習慣病と認知症・アルツハイマー病】
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] 脳血管内皮のフェノタイプ変化とアルツハイマー病.2017
- Author(s)
  林真一郎、里直行
- Organizer
  第42回日本脳卒中学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-26460931
[Presentation] Bidirectional Interactions between Diabetes and Alzheimer’s disease: Exploring Therapeutic Options2017
- Author(s)
  Naoyuki Sato
- Organizer
  2nd Geriatric Innovation Forum
- Place of Presentation
  Nagoya
- Year and Date
  2017-01-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] アミロイドβと糖尿病2017
- Author(s)
  里　直行
- Organizer
  第12回臨床ストレス応答学会シンポジウム1 【神経変性疾患における異常蛋白質の毒性、蓄積および伝播】
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] Bidirectional interaction between Alzheimer's disease and diabetes2017
- Author(s)
  Naoyuki Sato
- Organizer
  The 3rd NCGG-ICAH Symposium--Satellite Symposium of 59th Annual meeting of the Japan Geriatrics Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] Bidirectional interaction between Alzheimer's disease and diabetes2017
- Author(s)
  Naoyuki Sato
- Organizer
  The 3rd NCGG-ICAH Symposium--Satellite Symposium of 59th Annual meeting of the Japan Geriatrics Society
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] Bidirectional Interactions between Diabetes and Alzheimer’s disease2017
- Author(s)
  Naoyuki Sato
- Organizer
  The 7th BRI International Symposium 2017Alzheimer’s disease
- Place of Presentation
  Niigata
- Year and Date
  2017-03-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病による認知症促進機構の解明2017
- Author(s)
  里　直行
- Organizer
  第36回日本認知症学会学術集会シンポジウム18【生活習慣・生活習慣病と認知症・アルツハイマー病】
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] Bidirectional Interactions between Diabetes and Alzheimer’s disease: Exploring Therapeutic Options2017
- Author(s)
  Naoyuki Sato
- Organizer
  2nd Geriatric Innovation Forum
- Place of Presentation
  Nagoya
- Year and Date
  2017-01-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 糖尿病と認知症ー炎症性分子の関与も含めて2017
- Author(s)
  里　直行
- Organizer
  平成29年度日本歯周病学会60周年記念京都学会シンポジウムⅣ【超高齢社会を生き抜く歯周病予防・治療の考え方】
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] 糖尿病と認知症ー炎症性分子の関与も含めて2017
- Author(s)
  里　直行
- Organizer
  平成29年度日本歯周病学会60周年記念京都学会シンポジウムⅣ【超高齢社会を生き抜く歯周病予防・治療の考え方】
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] Bidirectional Interactions between Diabetes and Alzheimer’s disease2017
- Author(s)
  Naoyuki Sato
- Organizer
  The 7th BRI International Symposium 2017Alzheimer’s disease
- Place of Presentation
  Niigata
- Year and Date
  2017-03-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] アミロイドβと糖尿病2017
- Author(s)
  里　直行
- Organizer
  第12回臨床ストレス応答学会シンポジウム1 【神経変性疾患における異常蛋白質の毒性、蓄積および伝播】
- Invited
- Data Source
  KAKENHI-PROJECT-17H04154
[Presentation] 認知症の予防の最前線ー糖尿病が認知症を促進する分子メカニズムの解明2016
- Author(s)
  里　直行
- Organizer
  脳心血管抗加齢研究会2016
- Place of Presentation
  東京
- Year and Date
  2016-12-18
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病と認知症2016
- Author(s)
  里　直行
- Organizer
  第38回日本臨床栄養学会総会・第37回日本臨床栄養協会総会　第14回大連合大会
- Place of Presentation
  大阪
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病と認知症2016
- Author(s)
  里　直行
- Organizer
  第56回　近畿理学療法学術大会
- Place of Presentation
  和歌山
- Year and Date
  2016-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 糖尿病による認知症促進の鍵分子の探索2016
- Author(s)
  里　直行
- Organizer
  STROKE2016（第41回日本脳卒中学会総会、第45回日本脳卒中の外科学会学術集会、第32回スパズム・シンポジウム）
- Place of Presentation
  札幌
- Year and Date
  2016-04-15
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] THE PATHOLOGICAL INTERACTION BETWEEN DIABETES AND ALZHEIMER'S DISEASE2016
- Author(s)
  Naoyuki Sato
- Organizer
  11th International Symposium on Geriatrics and Gerontology
- Place of Presentation
  Oubu, Aichi
- Year and Date
  2016-02-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 認知症の予防の最前線ー糖尿病が認知症を促進する分子メカニズムの解明2016
- Author(s)
  里　直行
- Organizer
  脳心血管抗加齢研究会2016
- Place of Presentation
  東京
- Year and Date
  2016-12-18
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 糖尿病と認知症ー原因と結果の双方向の関係2016
- Author(s)
  里　直行
- Organizer
  第40回日本神経心理学会学術集会
- Place of Presentation
  熊本
- Year and Date
  2016-09-16
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 糖尿病と認知症ー原因と結果の双方向の関係2016
- Author(s)
  里　直行
- Organizer
  第40回日本神経心理学会学術集会
- Place of Presentation
  熊本
- Year and Date
  2016-09-16
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病と認知症2016
- Author(s)
  里　直行
- Organizer
  第38回日本臨床栄養学会総会・第37回日本臨床栄養協会総会　第14回大連合大会
- Place of Presentation
  大阪
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] THE PATHOLOGICAL INTERACTION BETWEEN DIABETES AND ALZHEIMER'S DISEASE2016
- Author(s)
  Naoyuki Sato
- Organizer
  11th International Symposium on Geriatrics and Gerontology
- Place of Presentation
  Oubu, Aichi
- Year and Date
  2016-02-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病による認知症促進の鍵分子の探索2016
- Author(s)
  里　直行
- Organizer
  STROKE2016（第41回日本脳卒中学会総会、第45回日本脳卒中の外科学会学術集会、第32回スパズム・シンポジウム）
- Place of Presentation
  札幌
- Year and Date
  2016-04-15
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病と認知症2016
- Author(s)
  里　直行
- Organizer
  第56回　近畿理学療法学術大会
- Place of Presentation
  和歌山
- Year and Date
  2016-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] アルツハイマー病進展における糖尿病および加齢による恒常性破綻機構の解明2015
- Author(s)
  里　直行
- Organizer
  第15回日本抗加齢医学会
- Place of Presentation
  博多
- Year and Date
  2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] アルツハイマー病進展における糖尿病および加齢による恒常性破綻機構の解明2015
- Author(s)
  里直行
- Organizer
  第15回日本抗加齢医学会
- Place of Presentation
  博多
- Year and Date
  2015-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 糖尿病とアルツハイマー病の病態連関2015
- Author(s)
  里直行
- Organizer
  第70回日本体力医学会大会
- Place of Presentation
  和歌山
- Year and Date
  2015-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] The Pathological Interaction between Diabetes and Alzhemer's Disease2015
- Author(s)
  Naoyuki Sato
- Organizer
  7th World Congress of the International Society for Vascular Behavioural and Cognitive Disorders
- Place of Presentation
  Tokyo
- Year and Date
  2015-09-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病とアルツハイマー病の病態連関2015
- Author(s)
  里直行
- Organizer
  第70回日本体力医学会大会
- Place of Presentation
  和歌山
- Year and Date
  2015-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 後天的危険因子からみたアルツハイマー病発症機構の解明2015
- Author(s)
  里直行
- Organizer
  第57回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-06-14
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] アルツハイマー病と生活習慣病―特に糖尿病との関連について2015
- Author(s)
  里直行
- Organizer
  CVMW2015 心血管代謝週間
- Place of Presentation
  神戸
- Year and Date
  2015-12-12
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 後天的危険因子からみたアルツハイマー病発症機構の解明2015
- Author(s)
  里直行
- Organizer
  第57回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-06-14
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] The Pathological Interaction between Diabetes and Alzhemer's Disease2015
- Author(s)
  Naoyuki Sato
- Organizer
  7th World Congress of the International Society for Vascular Behavioural and Cognitive Disorders
- Place of Presentation
  Tokyo
- Year and Date
  2015-09-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] アルツハイマー病と生活習慣病―特に糖尿病との関連について2015
- Author(s)
  里直行
- Organizer
  CVMW2015 心血管代謝週間
- Place of Presentation
  神戸
- Year and Date
  2015-12-12
- Invited
- Data Source
  KAKENHI-PROJECT-15K15272
[Presentation] 糖尿病とアルツハイマー病2014
- Author(s)
  里　直行
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 後天的危険因子からみたアルツハイマー病の解析2014
- Author(s)
  里　直行
- Organizer
  第14回日本抗加齢医学会総会、2014年6月7日、大阪
- Place of Presentation
  大阪
- Year and Date
  2014-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] 糖尿病によるアルツハイマー病促進機構2014
- Author(s)
  里　直行
- Organizer
  第56回日本老年医学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2014-06-12
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] アルツハイマー病と加齢性疾患のリンクから次世代認知症治療薬を開発する2014
- Author(s)
  里　直行
- Organizer
  科学技術振興財団研究開発戦略センター（JST-CRDS）「生命科学」俯瞰ワークショップ
- Place of Presentation
  東京
- Year and Date
  2014-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-26293167
[Presentation] ランチョン・セミナー"後天的危険因子からみたアルツハイマー病の解析"2013
- Author(s)
  里直行
- Organizer
  第28回日本老年学会総会・第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-04
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] ランチョン・セミナー "後天的危険因子からみたアルツハイマー病の解析"2013
- Author(s)
  里直行
- Organizer
  第28回日本老年学会総会・第55回日本老年医学会学術集
- Place of Presentation
  大阪
- Year and Date
  2013-06-04
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Possible involvements of Abeta, insulin signaling and tau phosphorylation in the pathological interaction between Alzheimer disease and diabetes2013
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC 2013 The Alzheimer's Association International Conference 2013
- Place of Presentation
  Boston
- Year and Date
  2013-07-14
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Abeta is prerequisite, but insufficient to cause tau phosphorylation in vivo : tau phosphorylation in APP mice by diabetes (POSTER PRIZE - 2nd Prize)2013
- Author(s)
  Naoyuki Sato
- Organizer
  3rd International Conference on Molecular Neurodegeneration -Basic biology and disease pathways
- Place of Presentation
  Cannes, France
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Role of adult common desease in the development of Alzheimer disease: Application to diagnostic and therapeutic indication2013
- Author(s)
  Naoyuki Sato, Ryuichi Morishita
- Organizer
  24th Biennial Joint Meeting
- Place of Presentation
  Cancun, Mexico
- Year and Date
  2013-04-22
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Role of adult common desease in the development of Alzheimer disease : Application to diagnostic and therapeutic indication2013
- Author(s)
  Naoyuki Sato
- Organizer
  24th Biennial Joint Meeting, International society for Neurochemistry, American Society for Neurochemistry
- Place of Presentation
  Cancun, Mexico
- Year and Date
  2013-04-22
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Amyloid precursor protein/presenilin 1 interaction is differentially regulated during Abeta40/42 production : detection using fusion constructs2013
- Author(s)
  N Sato, M Okochi, M Shinohara, G Thinakaran, S Takeda, A Fukumori, M Shinohara-Noma, M Mori-Ueda, H Hamada, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-02-09
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 最優秀演題賞"糖尿病はアルツハイマー病において恒常性維持機構を破綻させる"2013
- Author(s)
  里直行
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] シンポジウム5「体内老化因子」"アルツハイマー病と糖尿病の相互作用における体内老化因子"2013
- Author(s)
  里直行
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  横
- Year and Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Abeta is prerequisite, but insufficient to cause tau phosphorylation in vivo: tau phosphorylation in APP mice by diabetes2013
- Author(s)
  Naoyuki Sato
- Organizer
  3rd International Conference on Molecular Neurodegeneration - Basic biology and disease pathways
- Place of Presentation
  France
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] シンポジウム3 「生活習慣病と認知症」 "糖尿病とアルツハイマー病の発症機構"2013
- Author(s)
  里直行
- Organizer
  第3回日本認知症予防学会
- Place of Presentation
  新潟
- Year and Date
  2013-09-29
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] βアミロイド産生機構 : アミロイド前駆体蛋白とプレセニリンの融合蛋白を用いた解析2013
- Author(s)
  里直行、武田雅俊、樂木宏実、森下竜一
- Organizer
  第28回日本老年学会総会・第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-05
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Diabetes increases tau phosphorylation in APP mice : evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation2013
- Author(s)
  N Sato, M Mori-Ueda, T Tanaka, S Takeda, K Uchio-Yamada, H Ueda, M Shinohara, S Murayama, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-03-10
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] How does diabetes mellitus increase the incidence of Alzheimer's disease?2013
- Author(s)
  Naoyuki Sato
- Organizer
  The 86th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Fukuoka
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 糖尿病はアルツハイマー病モデルマウス脳においてタウのリン酸化を促進する2013
- Author(s)
  里直行, 田中稔久, 村山繁雄, 武田雅俊, 樂木宏実, 森下竜一
- Organizer
  第28回日本老年学会総会・第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-05
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 糖尿病はアルツハイマー病モデルマウス脳においてタウのリン酸化を促進する2013
- Author(s)
  里直行、田中稔久、村山繁雄、武田雅俊、樂木宏実、森下竜一
- Organizer
  第28回日本老年学会総会・第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-05
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Diabetes increases tau phosphorylation in APP mice : evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation2013
- Author(s)
  N Sato, M Mori-Ueda, T Tanaka, S Takeda, K Uchio-Yamada, H Ueda, M Shinohara, S Murayama, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11 th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-03-10
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Diabetes increases tau phosphorylation in APP mice: evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation2013
- Author(s)
  N Sato, M Mori-Ueda, T Tanaka, S Takeda, K Uchio-Yamada, H Ueda, M Shinohara, S Murayama, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-03-10
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Diabetes Disrupts Homeostasis against Alzheimer's Disease2013
- Author(s)
  Naoyuki Sato
- Organizer
  Asia-Pacific Diabetes and Obesity Study Group (APDO) symposium 2013
- Place of Presentation
  Tokyo
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 長期的な高脂肪食負荷はアルツハイマー病モデルマウスにおいて血中βアミロイドを増加させる2013
- Author(s)
  里直行、樂木宏実、森下竜一
- Organizer
  第28回日本老年学会総会・第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-06
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] βアミロイド産生機構 : アミロイド前駆体蛋白とプレセニリンの融合蛋白を用いた解析2013
- Author(s)
  里直行, 武田雅俊, 樂木宏実, 森下竜一
- Organizer
  第28回日本老年学会総会・第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-05
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] シンポジウム5 「体内老化因子」 "アルツハイマー病と糖尿病の相互作用における体内老化因子"2013
- Author(s)
  里直行
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Possible involvements of Abeta, insulin signaling and tau phosphorylation in the pathological interaction between Alzheimer disease and diabetes2013
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC 2013 The Alzheimer's Association International Conference 2013
- Place of Presentation
  Boston
- Year and Date
  2013-07-14
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Diabetes increases tau phosphorylation in APP mice : evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation2013
- Author(s)
  N Sato, M Mori-Ueda, T Tanaka, S Takeda, K Uchio-Yamada, H Ueda, M Shinohara, S Murayama, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-02-10
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Symposium 7 : Pathophysiology and therapeutics for dysfunction of higher brain function in metabolic disease. "How does diabetes mellitus increase the incidence of Alzheimer's disease?"2013
- Author(s)
  Naoyuki Sato
- Organizer
  The 86th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Fukuoka
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Symposia S16 : Strategies on biomarkers to diagnose Alzheimer's disease. Chair : Laura Morelli. "Role of adult common desease in the development of Alzheimer disease : Application to diagnostic and therapeutic indication"2013
- Author(s)
  Naoyuki Sato, Ryuichi Morishita
- Organizer
  24th Biennial Joint Meeting, International society for Neurochemistry, American Society for Neurochemistry
- Place of Presentation
  Cancun, Mexico
- Year and Date
  2013-04-22
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Amyloid precursor protein/presenilin 1 interaction is differentially regulated during Abeta40/42 production: detection using fusion constructs2013
- Author(s)
  N Sato, M Okochi, M Shinohara, G Thinakaran, S Takeda, A Fukumori, M Shinohara-Noma, M Mori-Ueda, H Hamada, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-03-09
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 長期的な高脂肪食負荷はアルツハイマー病モデルマウスにおいて血中β アミロイドを増加させる2013
- Author(s)
  里直行, 樂木宏実, 森下竜一
- Organizer
  第28回日本老年学会総会・第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-06
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Abeta is prerequisite, but insufficient to cause tau phosphorylation in vivo : tau phosphorylation in APP mice by diabetes2013
- Author(s)
  Naoyuki Sato
- Organizer
  (POSTER PRIZE - 2nd Prize). 3rd International Conference on Molecular Neurodegeneration - Basic biology and disease pathways
- Place of Presentation
  Cannes, France
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 最優秀演題賞 "糖尿病はアルツハイマー病において恒常性維持機構を破綻させる"2013
- Author(s)
  里直行
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] シンポジウム3「生活習慣病と認知症」"糖尿病とアルツハイマー病の発症機構"2013
- Author(s)
  里直行
- Organizer
  第3回日本認知症予防学会
- Place of Presentation
  新潟
- Year and Date
  2013-09-29
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Diabetes Disrupts Homeostasis against Alzheimer's Disease2013
- Author(s)
  Naoyuki Sato
- Organizer
  Asia-Pacific Diabetes and Obesity Study Group (APDO) symposium 2013
- Place of Presentation
  Tokyo
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Amyloid precursor protein/presenilin 1 interaction is differentially regulated during Abeta40/42 production : detection using fusion constructs2013
- Author(s)
  N Sato, M Okochi, M Shinohara, G Thinakaran, S Takeda, A Fukumori, M Shinohara-Noma, M Mori-Ueda, H Hamada, M Takeda, H Rakugi, R Morishita
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Year and Date
  2013-03-09
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Abeta is prerequisite, but insufficient to cause tau phosphorylation in vivo: tau phosphorylation in APP mice by diabetes2013
- Author(s)
  Naoyuki Sato
- Organizer
  3rd International Conference on Molecular Neurodegeneration - Basic biology and disease pathways
- Place of Presentation
  France
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Old APPxob/ob mice showed highly increased level of tau phosphorylation in brain2012
- Author(s)
  Naoyuki Sato, et al
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] シンポジウム「Common diseaseの体質と環境」"認知症の体質と環境"2012
- Author(s)
  里直行
- Organizer
  第62回日本体質医学会総会
- Place of Presentation
  大阪
- Year and Date
  2012-11-04
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Amyloid Precursor Protein/Presenilin 1 Interaction is Differentially Regulated during A1340/42 Production : Detection Using Fusion Constructs2012
- Author(s)
  Naoyuki Sato, Masayasu Okochi, Mitsuru Shinohara, Gopal Thinakaran, Shuko Takeda, Akio Fukumori, Motoko Shinohara-Noma, Mari Mori-Ueda, Hizuki Hamada, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  The 17th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  Osaka
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] シンポジウム「Common disease の体質と環境」 "認知症の体質と環境"2012
- Author(s)
  里直行
- Organizer
  第62回日本体質医学会総会
- Place of Presentation
  大阪
- Year and Date
  2012-11-04
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Roles of beta-amyloid and insulin resistance in the interaction between diabetes mellitus and Alzheimer's disease2012
- Author(s)
  Naoyuki Sato
- Organizer
  Gordon Research Conferences, Neurobiology of Brain Disorders
- Place of Presentation
  Stonehill
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Tau phosphorylation is increased by diabetes mellitus in APP transgenic mice2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  The 17th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  Osaka
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] The mechanisms by which diabetes mellitus increases the risk of Alzheimer's disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Keystone Symposia, Aging and Diseases of Aging
- Place of Presentation
  Tokyo
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Roles of beta-amyloid and insulin resistance in the interaction between diabetes mellitus and Alzheimer's disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Gordon Research Conferences, Neurobiology of Brain Disorders
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] The mechanisms by which diabetes mellitus increases the risk of Alzheimer's disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Keystone Symposia, Aging and Diseases of Aging
- Place of Presentation
  Tokyo
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Old APPxob/ob mice showed highly increased level of tau phosphorylation in brain2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Roles of beta-amyloid and insulin resistance in the interaction between diabetes mellitus and Alzheimer's disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Gordon Research Conferences, Neurobiology of Brain Disorders. Chair: Jie Shen, Vice Chair: Joachim J. Herz
- Place of Presentation
  Stonehill College
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] 認知症の危険因子と予防療法2012
- Author(s)
  里直行
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Statins up-regulate APP-CTF degradation and Abeta clearance2012
- Author(s)
  Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  KEYSTONE SYMPOSIA
- Place of Presentation
  Colorado, USA
- Year and Date
  2012-02-28
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Statins up-regulate APP-CTF degradation and Abeta clearance2012
- Author(s)
  Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  KEYSTONE SYMPOSIA
- Place of Presentation
  Colorado, USA
- Year and Date
  2012-02-28
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Old APPxob/ob mice showed highly increased level of tau phosphorylation in brain2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] シンポジウム3 「生活習慣病と認知症」"生活習慣病がアルツハイマー病病理および血管病変に与える影響"2012
- Author(s)
  里直行
- Organizer
  VAS-COG JAPAN 2012
- Place of Presentation
  東京
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] The mechanism by which diabetes mellitus increase the risk of Alzheimer disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Neuroscience2012
- Place of Presentation
  Nagoya
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Tau phosphorylation is ncreased by diabetes mellitus in APP transgenic mice2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  The 17th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  Osaka
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Statins up-regulate APP-CTF degradation and Abeta clearance2012
- Author(s)
  Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  KEYSTONE SYMPOSIA
- Place of Presentation
  Colorado, USA
- Year and Date
  2012-02-28
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Statins up-regulate APP-CTF degradation and Abeta clearance2012
- Author(s)
  Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  KEYSTONE SYMPOSIA- ApoE, Alzheimer's and Lipoprotein Biology
- Place of Presentation
  Keystone, Colorado
- Year and Date
  2012-02-28
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] The mechanisms by which diabetes mellitus increases the risk of Alzheimer's disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Keystone Symposia, Aging and Diseases of Aging
- Place of Presentation
  Tokyo
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] シンポジウム「脂質異常症の抗加齢医療」脂質異常症2012
- Author(s)
  里直行
- Organizer
  スタチンとアルツハイマー病"n 脳心血管抗加齢研究会2012
- Place of Presentation
  大阪
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] The mechanism by which diabetes mellitus increase the risk of Alzheimer disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Neuroscience2012
- Place of Presentation
  Nagoya
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Roles of beta-amyloid and insulin resistance in the interaction between diabetes mellitus and Alzheimer's disease2012
- Author(s)
  Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Gordon Research Conferences, Neurobiology of Brain Disorders
- Place of Presentation
  Stonehill College
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Amyloid Precursor Protein/Presenilin 1 Interaction is Differentially Regulated during Aβ40/42 Production : Detection Using Fusion Constructs2012
- Author(s)
  Naoyuki Sato, Masayasu Okochi, Mitsuru Shinohara, Gopal Thinakaran, Shuko Takeda, Akio Fukumori, Motoko Shinohara-Noma, Mari Mori-Ueda, Hizuki Hamada, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  The 17th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  Osaka
- Year and Date
  2012-12-07
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] シンポジウム「脂質異常症の抗加齢医療」脂質異常症、スタチンとアルツハイマー病"n2012
- Author(s)
  里直行
- Organizer
  脳心血管抗加齢研究会2012
- Place of Presentation
  大阪
- Year and Date
  2012-11-18
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Roles of beta-amyloid and insulin resistance in the interaction between diabetes mellitus and Alzheimer's disease2012
- Author(s)
  Naoyuki Sato
- Organizer
  Gordon Research Conferences, Neurobiology of Brain Disorders
- Place of Presentation
  Stonehill
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Roles of beta-amyloid and insulin resistance in the interaction between diabetes mellitus and Alzheimer's disease2012
- Author(s)
  Naoyuki Sato
- Organizer
  Gordon Research Conferences, Neurobiology of Brain Disorders
- Place of Presentation
  Stonehill
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] シンポジウム3「生活習慣病と認知症」"生活習慣病がアルツハイマー病病理および血管病変に与える影響"2012
- Author(s)
  里直行
- Organizer
  VAS-COG JAPAN 2012
- Place of Presentation
  東
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] 認知症の危険因子と予防療法2012
- Author(s)
  里直行
- Organizer
  第53回日本神経学会学術大会、シンポジウム「認知症疫学研究が提供するエビデンス」
- Place of Presentation
  東京
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZHEIMER DISEASE AND DIABETES MELLITUS2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Grobal Alzheimer's Research Summit
- Place of Presentation
  Madrid, Spain
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] インスリン抵抗性と認知症2011
- Author(s)
  里直行
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 認知症におけるアンチエイジングの役割と分子機序2011
- Author(s)
  里直行
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都(招聘講演)
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Mechanistic Interaction Between Alzheimer Disease And Diabetes Mellitus : Analysis Of Novel Mouse Models Of Alzheimer Disease With Diabetes2011
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZHEIMER DISEASE AND DIABETES MELLITUS2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Present and Future Alzheimer's Research / Grobal Alzheimer's Research Summit
- Place of Presentation
  Madrid
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病と生活習慣病2011
- Author(s)
  里直行
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC (Alzheimer Association International Conference)2011
- Place of Presentation
  Paris
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Increased Blood-Brain Barrier Vulnerability To Systemic Inflammation In Alzheimer Disease Mouse Model2011
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-10
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Mechanistic Interaction between Alzheimer Disease and Diabetes Mellitus: Analysis of Novel Mouse Models of Alzheimer Disease with Diabetes2011
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hiromi Rakugi, and Ryuichi Morishita
- Organizer
  The 10th International Conference on Alzheimer's and Parkinson's Diseases (ADPD 2011)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] インスリン抵抗性と認知症2011
- Author(s)
  里直行
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Dual Effects Of A Statin On Abeta Metabolism : Up-Regulation Of Degradation Of APP-CTF And Abeta Clearance2011
- Author(s)
  Sato N, Shinohara M, Takeda S, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 認知症に対する新たなアプローチ2011
- Author(s)
  里直行
- Organizer
  第53回日本老年医学会学術集会
- Place of Presentation
  東京(招聘講演)
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 認知症に対する新たなアプローチ2011
- Author(s)
  里直行
- Organizer
  第53回日本老年医学会学術集会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 新規マイクロダイアリシス法開発とアルツハイマー病研究への応用2011
- Author(s)
  里直行、武田朱公、樂木宏実、森下竜一
- Organizer
  第15回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Mechanistic Interaction Between Alzheimer Disease And Diabetes Mellitus : Analysis Of Novel Mouse Models Of Alzheimer Disease With Diabetes2011
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Mechanistic Interaction Between Alzheimer Disease And Diabetes Mellitus : Analysis Of Novel Mouse Models Of Alzheimer Disease With Diabetes2011
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Increased Blood-Brain Barrier Vulnerability To Systemic Inflammation In Alzheimer Disease Mouse Model2011
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases.
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-10
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] アルツハイマー病における血液脳関門の破綻による炎症の脳内への波及増幅2011
- Author(s)
  里直行、武田朱公、樂木宏実、森下竜一
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 認知症におけるアンチエイジングの役割と分子機序2011
- Author(s)
  里直行
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 認知症におけるアンチエイジングの役割と分子機序2011
- Author(s)
  里直行
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Dual Effects Of A Statin On Abeta Metabolism : Up-Regulation Of Degradation Of APP-CTF And Abeta Clearance2011
- Author(s)
  Sato N, Shinohara M, Takeda S, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Dual Effects Of A Statin On Abeta Metabolism : Up-Regulation Of Degradation Of APP-CTF And Abeta Clearance.2011
- Author(s)
  Sato N, Shinohara M, Takeda S, Rakugi H, Morishita R
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC (Alzheimer Association International Conference) 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病と生活習慣病2011
- Author(s)
  里直行
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病と生活習慣病2011
- Author(s)
  里直行
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都(招聘講演)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC(Alzheimer Association International Conference) 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 新規マイクロダイアリシス法開発とアルツハイマー病研究への応用2011
- Author(s)
  里直行、武田朱公、樂木宏実、森下竜一
- Organizer
  第15回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Dual Effects of a Statin on Abeta Metabolism: Up-regulation of Degradation of APP-CTF and Abeta Clearance2011
- Author(s)
  Naoyuki Sato, Mitsuru Shinohara, Shuko Takeda, Hiromi Rakugi, and Ryuichi Morishita
- Organizer
  The 10th International Conference on Alzheimer's and Parkinson's Diseases (ADPD 2011)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Dual Effects Of A Statin On Abeta Metabolism : Up-Regulation Of Degradation Of APP-CTF And Abeta Clearance2011
- Author(s)
  Sato N, Shinohara M, Takeda S, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-12
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾2011
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Alteration in Plasma Beta-amyloid Levels after Glucose Loading Could Be a Novel Diagnostic Marker for Alzheimer Disease2011
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, and Ryuichi Morishita
- Organizer
  The 10th International Conference on Alzheimer's and Parkinson's Diseases (ADPD 2011)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] インスリン抵抗性と認知症2011
- Author(s)
  里直行
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京(招聘講演)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZHEIMER DISEASE AND DIABETES MELLITUS2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Grobal Alzheimer's Research Summit
- Place of Presentation
  Madrid, Spain
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] インスリン抵抗性と認知症2011
- Author(s)
  里直行
- Organizer
  第30回日本認知症学会学術集会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 認知症に対する新たなアプローチ2011
- Author(s)
  里直行
- Organizer
  第53回日本老年医学会学術集会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 糖尿病がアルツハイマー病の後天的危険因子である機序2011
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Development of a novel microdialysis method to analyze molecules in brain interstitial fluid2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  第34回日本神経科学大会Neuroscience
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC (Alzheimer Association International Conference) 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Development of a novel microdialysis method to analyze molecules in brain interstitial fluid2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  第34回日本神経科学大会(Neuroscience2011)
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Increased Blood-brain Barrier Vulnerability to Systemic Inflammation in Alzheimer Disease Mouse Model2011
- Author(s)
  Shuko Takeda, Naoyuki Sato, Hiromi Rakugi, and Ryuichi Morishita
- Organizer
  The 10th International Conference on Alzheimer's and Parkinson's Diseases (ADPD 2011)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-10
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Increased Blood-Brain Barrier Vulnerability To Systemic Inflammation In Alzheimer Disease Mouse Model2011
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-10
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 認知症に対する新たなアプローチ2011
- Author(s)
  里直行
- Organizer
  第53回日本老年医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病と生活習慣病2011
- Author(s)
  里直行
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 糖尿病がアルツハイマー病の後天的危険因子である機序2011
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Development of a novel microdialysis method to analyze molecules in brain interstitial fluid2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  第34回日本神経科学大会(Neuroscience 2011)
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Increased Blood-Brain Barrier Vulnerability To Systemic Inflammation In Alzheimer Disease Mouse Model2011
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2011-03-10
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病における血液脳関門の破綻による炎症の脳内への波及増幅2011
- Author(s)
  里直行、武田朱公、樂木宏実、森下竜一
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 糖尿病がアルツハイマー病の後天的危険因子である機序2011
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  名古屋
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZH EIMER DISEASE ANDDIABETES MELLITUS2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Grobal Alzheimer' s Research Summit
- Place of Presentation
  Madrid, Spain
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 認知症におけるアンチエイジングの役割と分子機序2011
- Author(s)
  里直行
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Development of a novel microdialysis method to analyze molecules in brain interstitial fluid2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  第34回日本神経科学大会(Neuroscience2011)
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Alternation In Plasma Beta-Amyloid Levels After Glucose Loading Could Be A Novel Diagnostic Marker For Alzheimer Disease S.2011
- Author(s)
  Takeda S, Sato N, Yu H, Moriguchi A, Uchio-Yamada K,Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 新規マイクロダイアリシス法開発とアルツハイマー病研究への応用2011
- Author(s)
  里直行、武田朱公、樂木宏実、森下竜一
- Organizer
  第15回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Alternation In Plasma Beta-Amyloid Levels After Glucose Loading Could Be A Novel Diagnostic Marker For Alzheimer Disease S.2011
- Author(s)
  Takeda S, Sato N, Yu H, Moriguchi A, Uchio-Yamada K, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZHEIMER DISEASE AND DIABETES MELLITUS2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Grobal Alzheimer's Research Summit
- Place of Presentation
  Madrid, Spain
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Alternation In Plasma Beta-Amyloid Levels After Glucose Loading Could Be A Novel Diagnostic Marker For Alzheimer Disease S.2011
- Author(s)
  Takeda S, Sato N, Yu H, Moriguchi A, Uchio-Yamada K, Rakugi H, Morishita R.
- Organizer
  The 10th International Conference on Alzheimer's & Parkinson's Diseases
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾2011
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] アルツハイマー病における血液脳関門の破綻による炎症の脳内への波及増幅2011
- Author(s)
  里直行、武田朱公、樂木宏実、森下竜一
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾2011
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011
- Author(s)
  Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  AAIC (Alzheimer Association International Conference) 2011
- Place of Presentation
  Paris, France
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病病態は末梢臓器でのインスリン抵抗性を増悪させることで糖尿病病態を増悪させる2010
- Author(s)
  武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
- Organizer
  第52回日本老年医学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 糖代謝が血中B・アミロイド蛋白(AB)量に与える影響の検討:アルツハイマー病の新規診断指標への応用2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、湯久浩、守口篤、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾:Possible pathological interaction between diabetes mellitus and Alzheimer disease2010
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  Neuro 2010(第33回日本神経科学大会)
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Memory Impairment Associated with Recovery of Neurovascular Coupling2010
- Author(s)
  Shuko Takeda, Naoyuki Sato, Masanobu Kano, Toshio Ogihara, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension(ISH2010)
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 認知症病棟入院患者の周辺症状に対する抑肝散、非定型抗精神病薬、アンジオテンシン受容体拮抗薬の効果の検討2010
- Author(s)
  里直行、武田朱公、湯久浩、守口篤、楽木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010
- Author(s)
  武田朱公、里直行、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Diabetes accelerates memory dysfunction via cerebrovascular dysfunction in an Alzheimer mouse model with diabetes2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] スタチンによるアルツハイマー病予防効果の機序の解明2010
- Author(s)
  里直行、篠原充、島村宗尚、武田朱公、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] アンジオテンシンII受容体拮抗薬はAβによる脳血管反応性障害を抑制しアルツハイマー病モデルマウスの認知機能障害を改善する2010
- Author(s)
  武田朱公、里直行、荻原俊男、狩野方伸、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 全身糖代謝が血中Aβ濃度に与える影響の検討:糖負荷後血中Aβの変動を利用した新たなアルツハイマー病診断指標の探索2010
- Author(s)
  武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
- Organizer
  第52回日本老年医学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Diabetes mellitus exacerbated learning impairment via cerebrovascular inflammation and disturbance of brain insulin signaling in Alzheimer mouse models with diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Shinohara M, Rakugi H, Morishita R.
- Organizer
  Alzheimer's Association International Conference on Alzheimer Disease 2010
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Diabetes mellitus exacerbated learning impairment via cerebrovascular inflammation and disturbance of brain insulin signaling in Alzheimer mouse models with diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Shinohara M, Rakugi H, Morishita R.
- Organizer
  Alzheimer's Association International Conference on Alzheimer Disease 2010
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病病態における血管性危険因子の役割:糖尿病合併アルツハイマー病モデルマウスの解析から:Role of vascular risk factors in the pathogenesis of Alzheimer disease : Analysis of novel mouse models of Alzheimer disease with diabete2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、篠原充、楽木宏実、森下竜一
- Organizer
  Neuro 2010(第33回日本神経科学大会)
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 糖負荷による血中Aβの変動を利用した新たなアルツハイマー病診断指標の探索:全身糖代謝が血中Aβ濃度に与える影響の検討2010
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 糖尿病は脳血管障害と脳内インスリンシグナルの障害を介してアルツハイマー病脳内病態を修飾する2010
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病病態は末梢臓器でのインスリン抵抗性を増悪させることで糖尿病病態を増悪させる2010
- Author(s)
  武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
- Organizer
  第52回日本老年医学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Increased brain vulnerability to systemic inflammation in Alzheimer disease transgenic mouse model2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Organizer
  The 40th annual meeting of the Society for Neuroscience (Neuroscience 2010)
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Mechanistic interaction between Alzheimer disease and diabetes2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Organizer
  XXth World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 糖・エネルギー代謝が血中Abeta値に与える影響とその診断的応用2010
- Author(s)
  武田朱公、里直行、湯久浩、守口篤、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 症病棟入院患者の周辺症状に対する抑肝散、非定型抗精神病薬、アンジオテンシン受容体拮抗薬の効果の検討2010
- Author(s)
  里直行、武田朱公、湯久浩、守口篤、楽木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Possible Mutual Interaction Between Diabetes Mellitus and Alzheimer Disease : Generation of Novel Transgenic Mice Models of Alzheimer Disease With Diabetes2010
- Author(s)
  Sato N, Takeda S, Rakugi H, Morishita R.
- Organizer
  AHA Scientific Sessions 2010
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アンジオテンシンII受容体拮抗薬はABによる脳血管反応性障害を抑制しアルツハイマー病モデルマウスの認知機能障害を改善する2010
- Author(s)
  武田朱公、里直行、荻原俊男、狩野方伸、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Diabetes accelerates memory dysfunction via cerebrovascular dysfunction in an Alzheimer mouse model with diabetes2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Memory Impairment Associated with Recovery of Neurovascular Coupling2010
- Author(s)
  Takeda S, Sato N, Kano M, Ogihara T, Rakugi H, Morishita R.
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Possible Mutual Interaction Between Diabetes Mellitus and Alzheimer Disease : Generation of Novel Transgenic Mice Models of Alzheimer Disease With Diabetes2010
- Author(s)
  Sato N, Takeda S, Rakugi H, Morishita R.
- Organizer
  AHA Scientific Sessions 2010
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 糖・エネルギー代謝が血中Abeta値に与える影響とその診断的応用2010
- Author(s)
  武田朱公、里直行、湯久浩、守口篤、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 糖尿病とアルツハイマー病の相互的病態修飾機序の解明:糖尿病合併アルツハイマー病モデルマウスの作成とその病態解析2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 新規マイクロダイアライシス回収システムによる脳内ペプチドin vivo測定系の開発2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Possible Mutual Interaction Between Diabetes Mellitus and Alzheimer Disease: Generation of Novel Transgenic Mice Models of Alzheimer Disease With Diabetes2010
- Author(s)
  Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, and Ryuichi Morishita
- Organizer
  Microcirculation and Cerebral/Coronary/Peripheral Circulation, AHA Scientific Sessions 2010
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾: Possible pathological interaction between diabetes mellitus and Alzheimer disease2010
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  Neuro 2010 (第33回日本神経科学大会)
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 糖尿病合併アルツハイマー病モデルマウスにおける脳血管病態と脳内インスリンシグナルの変化2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第29回日本認知症学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病における血管性危険因子による病態修飾機序の解明2010
- Author(s)
  武田朱公、里直行、荻原俊夫、楽木宏実、森下竜一
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 短期間の高カロリー食負荷はアルツハイマー病モデルマウスの認知機能障害を改善する2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] HMG還元酵素阻害薬フルバスタチンのAB代謝作用の解析2010
- Author(s)
  篠原充、里直行、武田朱公、野間基子、森下竜一
- Organizer
  第29回日本認知症学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 糖尿病合併アルツハイマー病モデルマウスにおける脳血管病態と脳内インスリンシグナルの変化2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第29回日本認知症学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 糖尿病は脳血管障害と脳内インスリンシグナルの障害を介してアルツハイマー病脳内病態を修飾する2010
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Diabetes Accelerated Memory Dysfunction via Cerebrovascular Inflammation and Beta-Amyloid Deposition in Alzheimer Mouse Model : Generation of Novel Transgenic Mouse Models of Alzheimer Disease with Diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 糖尿病とアルツハイマー病の相互的病態修飾機序の解明:糖尿病合併アルツハイマー病モデルマウスの作成とその病態解析2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 全身糖代謝が血中AB濃度に与える影響の検討:糖負荷後血中ABの変動を利用した新たなアルツハイマー病診断指標の探索2010
- Author(s)
  武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
- Organizer
  第52回日本老年医学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 認知症病棟入院患者の周辺症状に対する抑肝散、非定型抗精神病薬、アンジオテンシン受容体拮抗薬の効果の検討2010
- Author(s)
  里直行、武田朱公、湯久浩、守口篤、楽木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 糖負荷による血中ABの変動を利用した新たなアルツハイマー病診断指標の探索:全身糖代謝が血中AB濃度に与える影響の検討2010
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 新規マイクロダイアライシス回収システムによる脳内ペプチドin vivo測定系の開発2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Possible Mutual Interaction Between Diabetes Mellitus and Alzheimer Disease : Generation of Novel Transgenic Mice Models of Alzheimer Disease With Diabetes2010
- Author(s)
  Sato N, Takeda S, Rakugi H, Morishita R.
- Organizer
  AHA Scientific Sessions 2010
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 新規マイクロダイアライシス回収システムによる脳内ペプチドin vivo測定系の開発2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 糖尿病とアルツハイマー病の相互的病態修飾機序の解明:糖尿病合併アルツハイマー病モデルマウスの作成とその病態解析2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病病態における血管性危険因子の役割:糖尿病合併アルツハイマー病モデルマウスの解析から:Role of vascular risk factors in the pathogenesis of Alzheimer disease : Analysis of novel mouse models of Alzheimer disease with diabete2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、篠原充、楽木宏実、森下竜一
- Organizer
  Neuro 2010(第33回日本神経科学大会)
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病病態は末梢臓器でのインスリン抵抗性を増悪させることで糖尿病病態を増悪させる2010
- Author(s)
  武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
- Organizer
  第52回日本老年医学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 短期間の高カロリー食負荷はアルツハイマー病モデルマウスの認知機能障害を改善する2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 短期間の高カロリー食負荷はアルツハイマー病モデルマウスの認知機能障害を改善する2010
- Author(s)
  武田朱公、里直行、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] HMG還元酵素阻害薬フルバスタチンのAβ代謝作用の解析2010
- Author(s)
  篠原充、里直行、武田朱公、野間基子、森下竜一
- Organizer
  第29回日本認知症学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Diabetes Accelerated Memory Dysfunction via Cerebrovascular Inflammation and Beta-Amyloid Deposition in Alzheimer Mouse Modle : Generation of Novel Transgenic Mouse Models of Alzheimer Disease wih Diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Memory Impairment Associated with Recovery of Neurovascular Coupling.2010
- Author(s)
  Takeda S, Sato N, Kano M, Ogihara T, Rakugi H, Morishita R
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 認知症病棟入院患者の周辺症状に対する抑肝散、非定型抗精神病薬、アンジオテンシン受容体拮抗薬の効果の検討2010
- Author(s)
  里直行、武田朱公、湯久浩、守口篤、楽木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Diabetes mellitus exacerbated learning impairment via cerebrovascular inflammation and disturbance of brain insulin signaling in Alzheimer mouse models with diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Shinohara M, Rakugi H, Morishita R.
- Organizer
  Alzheimer's Association International Conference on Alzheimer Disease 2010
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Increased brain vulnerability to systemic inflammation in Alzheimer disease transgenic mouse model2010
- Author(s)
  Shuko Takeda, Naoyuki Sato, Hiromi Rakugi, and Ryuichi Morishita
- Organizer
  The 40th annual meeting of the Society for Neuroscience (Neuroscience 2010)
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アンジオテンシンII受容体拮抗薬はAβによる脳血管反応性障害を抑制しアルツハイマー病モデルマウスの認知機能障害を改善する2010
- Author(s)
  武田朱公、里直行、荻原俊男、狩野方伸、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Diabetes Accelerated Memory Dysfunction via Cerebrovascular Inflammation and Beta-Amyloid Deposition in Alzheimer Mouse Model: Generation of Novel Transgenic Mouse Models of Alzheimer Disease with Diabetes2010
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension(ISH2010)
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Diabetes Accelerated Memory Dysfunction via Cerebrovascular Inflammation and Beta-Amyloid Deposition in Alzheimer Mouse Model : Generation of Novel Transgenic Mouse Models of Alzheimer Disease with Diabetes2010
- Author(s)
  Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-27
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 糖代謝が血中β・アミロイド蛋白(Aβ)量に与える影響の検討:アルツハイマー病の新規診断指標への応用2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、湯久浩、守口篤、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 全身糖代謝が血中Aβ濃度に与える影響の検討:糖負荷後血中Aβの変動を利用した新たなアルツハイマー病診断指標の探索2010
- Author(s)
  武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
- Organizer
  第52回日本老年医学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Diabetes mellitus exacerbated learning impairment via cerebrovascular inflammation and disturbance of brain insulin signaling in Alzheimer mouse models with diabetes2010
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  Alzheimer's Association International Conference on Alzheimer Disease 2010(ICAD2010)
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Diabetes accelerates memory dysfunction via cerebrovascular dysfunction in an Alzheimer mouse model with diabetes2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 糖代謝が血中β・アミロイド蛋白(Aβ)量に与える影響の検討:アルツハイマー病の新規診断指標への応用2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、湯久浩、守口篤、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Mechanistic interaction between Alzheimer disease and diabetes2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Organizer
  XXth World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 糖・エネルギー代謝が血中Abeta値に与える影響とその診断的応用2010
- Author(s)
  武田朱公、里直行、湯久浩、守口篤、樂木宏実、森下竜一
- Organizer
  第21回日本老年医学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010
- Author(s)
  武田朱公、里直行、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] HMG還元酵素阻害薬フルバスタチンのAβ代謝作用の解析2010
- Author(s)
  篠原充、里直行、武田朱公、野間基子、森下竜一
- Organizer
  第29回日本認知症学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] スタチンによるアルツハイマー病予防効果の機序の解明2010
- Author(s)
  里直行、篠原充、島村宗尚、武田朱公、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 糖負荷による血中Aβの変動を利用した新たなアルツハイマー病診断指標の探索:全身糖代謝が血中Aβ濃度に与える影響の検討2010
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Increased brain vulnerability to systemic inflammation in Alzheimer disease transgenic mouse model2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Organizer
  The 40th annual meeting of the Society for Neuroscience (Neuroscience 2010)
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Mechanistic interaction between Alzheimer disease and diabetes2010
- Author(s)
  Takeda S, Sato N, Rakugi H, Morishita R.
- Organizer
  XXth World Congress of the International Society for Heart Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] アルツハイマー病病態における血管性危険因子の役割:糖尿病合併アルツハイマー病モデルマウスの解析から:Role of vascular risk factors in the pathogenesis of Alzheimer disease : Analysis of novel mouse models of Alzheimer disease with diabete2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、篠原充、楽木宏実、森下竜一
- Organizer
  Neuro 2010 (第33回日本神経科学大会)
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病における血管性危険因子による病態修飾機序の解明2010
- Author(s)
  武田朱公、里直行、荻原俊夫、楽木宏実、森下竜一
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病における血管性危険因子による病態修飾機序の解明2010
- Author(s)
  武田朱公、里直行、荻原俊夫、楽木宏実、森下竜一
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Memory Impairment Associated with Recovery of Neurovascular Coupling2010
- Author(s)
  Takeda S, Sato N, Kano M, Ogihara T, Rakugi H, Morishita R.
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] スタチンによるアルツハイマー病予防効果の機序の解明2010
- Author(s)
  里直行、篠原充、島村宗尚、武田朱公、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾:Possible pathological interaction between diabetes mellitus and Alzheimer disease2010
- Author(s)
  里直行、武田朱公、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  Neuro 2010(第33回日本神経科学大会)
- Place of Presentation
  神戸(招待講演)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 糖尿病合併アルツハイマー病モデルマウスにおける脳血管病態と脳内インスリンシグナルの変化2010
- Author(s)
  武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
- Organizer
  第29回日本認知症学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Memory Impairment Associated with Recovery of Neurovascular Coupling2010
- Author(s)
  Takeda S, Sato N, Kano M, Ogihara T, Rakugi H, Morishita R.
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-28
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010
- Author(s)
  武田朱公、里直行、楽木宏実、森下竜一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] 糖尿病は脳血管障害と脳内インスリンシグナルの障害を介してアルツハイマー病脳内病態を修飾する2010
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] reduces Aβlevels in brain by upregulating APP-CTFs degradation and Aβ clearance.2009
- Author(s)
  M.Shinohara, N.Sato, H.Kurinami, D.Takeuchi, S.Takeda, M.Noma, H.Rakugi, R.Morishita
- Organizer
  International Conference on Molecular Neurodegeneration
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Fluvastatin(an HMG-CoA reductase inhibitor) reduces Aβlevels in brain by upregulating2009
- Author(s)
  M. Shinohara, N. Sato, H. Kurinami, D. Takeuchi, S. Takeda, M. Noma, H. Rakugi, R. Morishita
- Organizer
  APP-CTFs degradation and Aβclearance Nuroscience2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾機序の解明 : 新規病態合併モデル動物の作成とその解析2009
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、栗波仁美、竹内大亮、篠原充、楽木宏美、森下竜一
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾機序の解明 : 新規病態合併モデル動物の作成とその解析2009
- Author(s)
  武田朱公, 里直行, 内尾こずえ, 澤田京子, 國枝孝典, 栗波仁美, 竹内大亮, 篠原充, 楽木宏美, 森下竜一
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] アルツハイマー病根本治療を目指したフルバスタチンの新規抗Aβ作用の解明2009
- Author(s)
  篠原充、里直行、栗波仁美、竹内大亮、武田朱公、野間基子、楽木宏美、森下竜一
- Organizer
  アルツハイマー病根本治療を目指したフルバスタチンの新規抗Aβ作用の解明
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] アルツハイマー病と糖尿病の相互的病態修飾機序の解明:新規病態合併モデル動物の作成とその解析2009
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、栗波仁美、竹内大亮、楽木宏美、森下竜一
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-06-18
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Fluvastatin (an HMG-CoA reductase inhibitor) reduces Abeta levels in brain by upregulating APP-CTFs degradation and Abeta clearance2009
- Author(s)
  篠原充, 里直行, 栗波仁美, 竹内大亮, 武田朱公, 野間基子, 楽木宏美, 森下竜一
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] The pharmacodynamic mechanisms of cognition enhancement by antihypertensive drugs2009
- Author(s)
  里直行
- Organizer
  IAGG world congress of GERONTOLOGY and GERIATRICS
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 血糖状態及び血中インスリン値は血中Aβ量を修飾する:血中Aβ値のアルツハイマー病バイオマーカーとしての最適化条件の検討2009
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、栗波仁美、竹内大亮、楽木宏美、森下竜一
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 血糖状態及び血中インスリン値は血中Aβ量を修飾する : 血中Aβ値のアルツハイマー病バイオマーカーとしての最適化条件の検討2009
- Author(s)
  武田朱公, 里直行, 内尾こずえ, 澤田京子, 國枝孝典, 篠原充, 栗波仁美, 竹内大亮, 楽木宏美, 森下竜一
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Fluvastatin (an HMG-CoA reductase inhibitor) reduces Abeta levels in brain by upregulating APP-CTFs degradation and Abeta clearance2009
- Author(s)
  M. Shinohara, N. Sato, H. Kurinami, D. Takeuchi, S. Takeda, M. Noma, H. Rakugi, R
- Organizer
  Neuroscience
- Place of Presentation
  Chicago
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] アルツハイマー病根本治療を目指したフルバスタチンの新規抗Aβ作用の解明2009
- Author(s)
  篠原充, 里直行, 栗波仁美, 竹内大亮, 武田朱公, 野間基子, 楽木宏美, 森下竜一
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Possible mutual interaction between diabetes mellitus and Alzheimer's disease : Generation of novel transgenic mice models of Alzheimer's disease with diabetic conditions2009
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  ICAD (International Conference on Alzheimer's Disease) 2009
- Place of Presentation
  Vienna, Austria
- Year and Date
  2009-07-15
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] アルツハイマー病根本治療を目指したフルバスタチンの新規抗Aβ作用の解明2009
- Author(s)
  篠原充、里直行、栗波仁美、竹内大亮、武田朱公、野間基子、楽木宏美、森下竜一
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Fluvastatin (an HMG-CoA reductase inhibitor) reduces Abeta levels in brain by upregulating APP-CTFs degradation and Abeta clearance2009
- Author(s)
  M.Shinohara, N.Sato, H.Kurinami, D.Takeuchi, S.Takeda, M.Noma, H.Rakugi, R.Morishita
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago, USA
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Possible mutual interaction between diabetes mellitus and Alzheimer's disease : Generation of novel transgenic mice models of Alzheimer's disease with diabetic conditions2009
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
- Organizer
  ICAD (International Conference on Alzheimer's Disease) 2009
- Place of Presentation
  Vienna, Austria
- Year and Date
  2009-07-15
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] 血糖状態及び血中インスリン値は血中Aβ量を修飾する : 血中Aβ値のアルツハイマー病バイオマーカーとしての最適化条件の検討2009
- Author(s)
  武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、栗波仁美、竹内大亮、楽木宏美、森下竜一
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2009-06-19
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Possible mutual interaction between diabetes mellitus and Alzheimer' s disease : Generation of novel transgenic mice models of Alzheimer' s disease with diabetic conditions2009
- Author(s)
  Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru Shinohara, Hiromi Rakugi, and Ryuichi Morishita
- Organizer
  ICAD(International Conference on Alzheimer' s Disease) 2009
- Place of Presentation
  Vienna, Austria
- Year and Date
  2009-07-15
- Data Source
  KAKENHI-PROJECT-21659179
[Presentation] Improvement of cognitive decline and cerebrovascular dysfunction in amouse model of Alzheimer disease with angiotensin receptor blocker, 01mesaratn2008
- Author(s)
  Takeda s, Sato N, Rakugi H, Ogihara T, Morishita R
- Organizer
  22^<nd> Scientific Meeting International Society of Hypertension
- Place of Presentation
  Berlin
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 超音波を用いた肝細胞増殖因子遺伝子導入はマウスにおけるベーダ・アミロイド起因性認知機能を改善させる2008
- Author(s)
  竹内大亮, 里直行, 栗波仁美, 楽木宏実, 荻原俊男, 森下竜一
- Organizer
  第50回日本老年医学会総会
- Place of Presentation
  千葉
- Year and Date
  2008-06-20
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] The protective effect of fluvastatin, an HMG-CoA reductase inhibitor, on the Aβ brain accumulation.2008
- Author(s)
  M. Shinohara, N. Sato, H. Kurinami, D. Takeuchi, S. Takeda, F. Nakagami, R. Morishita
- Organizer
  Neuroscience
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] ATI受容体格抗薬は脳血管反応性を改善することでアルツハイマー病モデルマウスの認知機能を回復させる2008
- Author(s)
  武田朱公, 里直行, 荻原俊男, 楽木宏実, 森下竜一
- Organizer
  第12回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  熊本
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] The protective effect of fluvastatin, a HMG-CoA reductase inhibitor, on the Aβ brain accumulation2008
- Author(s)
  Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda s, Morishita R
- Organizer
  Neuroscience 2008, Society for Neuroscience
- Place of Presentation
  Washington, DC
- Year and Date
  2008-11-16
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] 脳血管作動性の改善を介したアルツハイマー病モデルマウスに対するATI受容体措抗薬による治療効果の検討2008
- Author(s)
  武田朱公, 里直行, 荻原俊男, 楽木宏実, 森下竜一
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-20590697
[Presentation] Gene Transfer of HGF by microbubble-enhanced ultrasound improved Aβ-induced Memory Impairment in Mice2007
- Author(s)
  Takeuchi D, Sato N, Shimamura M, Kurinami H, Takeda S, Shinohara M, Suzuki S, Kojima M, Ogihara T and Morishita R.
- Organizer
  Neuroscience 2007
- Place of Presentation
  San Diego USA
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-17689034
[Presentation] Ultrasound-mediated gene transfer of HGF improved Abeta-induced cognitive impairment in mice associated with upregulation of BDNR recovery of and downregulation of oxidative stress.2007
- Author(s)
  Takeuchi D, Sato N, Shimamura M, Kurinami H, Takeda S, Shinohara M, Suzuki S, Kojima M, Ogihara T and Morishita R.
- Organizer
  ASGT 10th Annual Meeting
- Place of Presentation
  Seattle USA
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-17689034
[Presentation] Ultrasound-mediated gene transfer of HGF improved Abeta-induced cognitive impairment in mice associated with upregulat ion of BDNF and downregulation of oxidative stress.2007
- Author(s)
  Takeuchi D, Sato N, Shimamura M, Kurinami H, Takeda S, Shinohara M, Suzuki S, Kojima M, Ogihara T and Morishita R.
- Organizer
  Neuroscience 2007
- Place of Presentation
  San Diego
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-18659334
[Presentation] Amyloid precursor protein/presenilin 1 interaction is differentially regulated during Abeta40/42 production: detection using fusion constructs
- Author(s)
  Naoyuki Sato
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 糖尿病とアルツハイマー病の発症機構
- Author(s)
  里直行
- Organizer
  第3回日本認知症予防学会
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 認知症の体質と環境
- Author(s)
  里直行
- Organizer
  第62回日本体質医学会総会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] The mechanisms by which diabetes mellitus increases the risk of Alzheimer's disease
- Author(s)
  Naoyuki Sato
- Organizer
  Keystone Symposia, Aging and Diseases of Aging
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] アルツハイマー病と糖尿病の相互作用における体内老化因子
- Author(s)
  里　直行
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] The mechanism by which diabetes mellitus increase the risk of Alzheimer disease
- Author(s)
  Naoyuki Sato
- Organizer
  Neuroscience2012
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Amyloid Precursor Protein/Presenilin 1 Interaction is Differentially Regulated during Aβ40/42 Production : Detection Using Fusion Constructs
- Author(s)
  Naoyuki Sato
- Organizer
  The 17th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Tau phosphorylation is increased by diabetes mellitus in APP transgenic mice
- Author(s)
  Naoyuki Sato
- Organizer
  The 17th Takeda Science Foundation Symposium on Bioscience
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Molecular Mechanisms Linking Alzheimer's Disease And Its Non-Genetic Risk Factors - Towards Novel Therapeutic Strategies
- Author(s)
  Chairs : Naoyuki Sato, Makoto Higuchi
- Organizer
  The 20th IAGG World Congress of Gerontology and Geriatrics
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] How does diabetes mellitus increase the incidence of Alzheimer's disease?
- Author(s)
  Naoyuki Sato
- Organizer
  The 86th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Fukuoka
- Invited
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] アルツハイマー病と糖尿病の相互作用における体内老化因子
- Author(s)
  里直行
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Molecular Mechanisms Linking Alzheimer's Disease And Its Non-Genetic Risk Factors - Towards Novel Therapeutic Strategies (SS24 517-B). 1. Pathological interaction between Alzheimer's disease and diabetes mellitus Naoyuki Sato
- Author(s)
  Chairs: Naoyuki Sato, Makoto Higuchi
- Organizer
  The 20th IAGG World Congress of Gerontology and Geriatrics
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] 糖尿病とアルツハイマー病の発症機構
- Author(s)
  里　直行
- Organizer
  第3回日本認知症予防学会
- Place of Presentation
  新潟
- Invited
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Diabetes increases tau phosphorylation in APP mice: evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation
- Author(s)
  Naoyuki Sato
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] Pathological interaction between Alzheimer's disease and diabetes mellitus
- Author(s)
  Naoyuki Sato
- Organizer
  The 20th IAGG World Congress of Gerontology and Geriatrics
- Place of Presentation
  korea
- Invited
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] How does diabetes mellitus increase the incidence of Alzheimer's disease?
- Author(s)
  Naoyuki Sato
- Organizer
  The 86th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Fukuoka
- Invited
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] 生活習慣病がアルツハイマー病病理および血管病変に与える影響
- Author(s)
  里　直行
- Organizer
  VAS-COG JAPAN 2012
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Diabetes increases tau phosphorylation in APP mice: evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation
- Author(s)
  Naoyuki Sato
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] The mechanisms by which diabetes mellitus increases the risk of Alzheimer's disease
- Author(s)
  Naoyuki Sato
- Organizer
  Keystone Symposia, Aging and Diseases of Aging
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22390145
[Presentation] The mechanisms by which diabetes mellitus increases the risk of Alzheimer's disease
- Author(s)
  Naoyuki Sato
- Organizer
  Keystone Symposia, Aging and Diseases of Aging
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Old APPxob/ob mice showed highly increased level of tau phosphorylation in brain
- Author(s)
  Naoyuki Sato
- Organizer
  Neuroscience 2012　（Society for Neuroscience)
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 脂質異常症の抗加齢医療
- Author(s)
  里　直行
- Organizer
  脳心血管抗加齢研究会2012
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Pathological interaction between Alzheimer's disease and diabetes mellitus
- Author(s)
  Naoyuki Sato
- Organizer
  The 20th IAGG World Congress of Gerontology and Geriatrics
- Place of Presentation
  Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Diabetes increases tau phosphorylation in APP mice: evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylatio
- Author(s)
  Naoyuki Sato
- Organizer
  The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Role of adult common desease in the development of Alzheimer disease: Application to diagnostic and therapeutic indication
- Author(s)
  Naoyuki Sato, Ryuichi Morishita
- Organizer
  24th Biennial Joint Meeting, International society for Neurochemistry, American Society for Neurochemistry
- Place of Presentation
  Mexico
- Invited
- Data Source
  KAKENHI-PROJECT-24659349
[Presentation] Role of adult common desease in the development of Alzheimer disease: Application to diagnostic and therapeutic indication
- Author(s)
  Naoyuki Sato, Ryuichi Morishita
- Organizer
  24th Biennial Joint Meeting, International society for Neurochemistry, American Society for Neurochemistry
- Place of Presentation
  Mexico
- Invited
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] The mechanism by which diabetes mellitus increase the risk of Alzheimer disease
- Author(s)
  里　直行
- Organizer
  Neuroscience2012
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] 認知症の危険因子と予防療法
- Author(s)
  里　直行
- Organizer
  第53回日本神経学会学術大会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23390187
[Presentation] Common diseaseの体質と環境
- Author(s)
  里　直行
- Organizer
  第62回日本体質医学会総会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23390187

1. HAYASHI Shinichiro (20396740)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
2. UCHIO Kozue (70373397)

# of Collaborated Projects: 4 results

# of Collaborated Products: 68 results
3. MURAYAMA Shigeo (50183653)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. TAKEYA Yasushi (70590339)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 宮崎早月 (60452439)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. MORISHITA Ryuichi (40291439)

# of Collaborated Projects: 3 results

# of Collaborated Products: 152 results
7. UEDA Hironori (90543463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. YAMAMOTO Akitsugu (30174775)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. IKEUCHI Takeshi (20372469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Matsushita Kenji (90253898)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 樂木宏実 (20252679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 佐治直樹 (30624910)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 多田浩之 (70431632)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 山田匡恵 (90439456)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 長谷川成人 (10251232)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
16. 齊藤祐子 (60344066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
17. 奥崎大介 (00346131)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. TAKEYA Miyuki

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. MUKOUZONO Masahiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. SHIMAMURA Munehisa (60422317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
21. Yamamoto Koichi (00528424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 谷山義明 (60372611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
23. 田中稔久 (10294068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 沢村達也 (30243033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 杉本研 (20437403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 長野清一 (40362727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 津田玲生 (30333355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 櫻井孝 (50335444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 徳武孝允 (00707838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 豊島靖子 (20334675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 春日健作 (70547546)

# of Collaborated Projects: 1 results

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32. 武田朱公 (50784708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 伊藤義晃 (50511044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 道川誠 (40270912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 石原裕一 (50261011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. TEZUKA Toshiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. SAITO Kento

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. MIYASHITA Akinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. HARA Norikazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. TSUKIE Tamao

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 竹田浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SATO Naoyuki 里 直行

Research Projects

Research Products

Co-Researchers

全身の代謝および老化からみたアルツハイマー病の解析Principal Investigator

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Principal Investigator

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Multifaceted analysis of molecular mechanisms by which diabetes and aging are non-genetic risk factors for dementiaPrincipal Investigator

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Principal Investigator

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Principal Investigator

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Interactions between diabetes, aging and dementiaPrincipal Investigator

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Investigation of key molecules involved in bidirectional interactions between diabetes and dementiaPrincipal Investigator

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Analysis of the mechanism of homeostatic maintenance against Alzheimer's disease and its failure due to diabetesPrincipal Investigator

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Modification of diabetic phenotype by Alzheimer's diseasePrincipal Investigator

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SATO Naoyuki 里直行