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naka kazuhito  仲 一仁

… Alternative Names

NAKA Kazuhito  仲 一仁

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Researcher Number 70372688
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-6646-6004
External Links
Affiliation (Current) 2022: 広島大学, 原爆放射線医科学研究所, 准教授
Affiliation (based on the past Project Information) *help 2015 – 2022: 広島大学, 原爆放射線医科学研究所, 准教授
2014: 金沢大学, がん進展制御研究所, 准教授
2009 – 2011: Kanazawa University, がん研究所, 准教授
2007 – 2008: Kanazawa University, がん研究所, 助教
2005 – 2006: 金沢大学, がん研究所, 助手
2004: 岡山大学, 大学院・医歯学総合研究科, 助手
Review Section/Research Field
Principal Investigator
Experimental pathology / General medical chemistry / Tumor biology / Virology / Tumor biology and related fields / Basic Section 50010:Tumor biology-related / Medium-sized Section 48:Biomedical structure and function and related fields
Except Principal Investigator
Urology / Biological Sciences
Keywords
Principal Investigator
がん幹細胞 / CML幹細胞 / 抗がん剤抵抗性 / CML / がん / 慢性骨髄性白血病 / チロシンキナーゼ阻害剤抵抗性 / 再発 / 癌 / メタボローム … More / Foxo3a / 代謝 / C型肝炎ウイルス / NS5B / RNA依存RNAポリメラーゼ / IFN-β / TLR3 / IRF-3 / 細胞周期 / DNA修復 / 動物モデル / FOXO / TGF-・阻害剤 / TGF-β阻害剤 / 白血病幹細胞 / フォークヘッド転写因子 / 白血病 / Smad3 / p38 MAPK / マウスモデル / 非臨床試験 / TGF-beta / チロシンキナーゼ阻害剤 / がん微小環境 / TGF-β / 微小環境 / 乳がん幹細胞 / 代謝産物 / 乳がん / 休眠状態 / MMTV-PyVT / Lgr4 / Wnt/beta-catenin / Wnt-beta-catenin / Wnt-beta-Catenin / Wnt/β-catenin / ゲノム編集 / Wnt-β-catenin / ジペプチド / オンコ ニュートリエント / トランスポーター / 再生医療 / トランスポータ / 再発治療 / オンコ ニュートリエント / リゾリン脂質 / リゾホスフォリパーゼD / Gdpd3 / リポクオリティ / リゾリン脂質代謝 / FOXO3a / beta-catenin / オルガノイド / オメガ3脂肪酸 / DHA代謝 / Gタンパク質共役受容体 / V-ATPase / ピノサイトーシス … More
Except Principal Investigator
抗がん剤耐性 / 膀胱癌 / 微小環境 / シグナル伝達 / 生体材料 / 生体イメージング / ゲノム科学 / がん微小環境 / がん浸潤 / 転移 / 血管新生 / リンパ管新生 / ゲノム医学 / 抗がん剤耐性膀胱癌 / 尿路上皮癌 / p38 / 化学療法耐性 / 抗癌剤耐性 / 癌 Less
  • Research Projects

    (13 results)
  • Research Products

    (148 results)
  • Co-Researchers

    (51 People)
  •  Role of omega-3 fatty acid metabolism in cancer stem cellsPrincipal Investigator

    • Principal Investigator
      仲 一仁
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Hiroshima University
  •  Role of lysophospholipid metabolism enzyme Gdpd3 in regulating lipoquality in cancer stem cellsPrincipal Investigator

    • Principal Investigator
      仲 一仁
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Hiroshima University
  •  p38 MAPK is involved in the development of resistance to chemotherapy in urothelial carcinoma

    • Principal Investigator
      Shinmei Shunsuke
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Hiroshima Nishi Medical Center
      Hiroshima University
  •  Role of Stemness Factor Lgr4 for Therapeutic Resistance in CML Stem CellsPrincipal Investigator

    • Principal Investigator
      Naka Kazuhito
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Hiroshima University
  •  Novel role of dipeptide species as an onco-nututrient to maintain cancer stem cellsPrincipal Investigator

    • Principal Investigator
      NAKA KAZUHITO
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Tumor biology and related fields
    • Research Institution
      Hiroshima University
  •  To develop novel therapeutic targets in bladder cancer based on stemness

    • Principal Investigator
      Hayashi Tetsutaro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Hiroshima University
  •  Stem cell-specific phosphorylation of Smad3 for regulating self-renewal capacity in CML stem cellsPrincipal Investigator

    • Principal Investigator
      Naka Kazuhito
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Hiroshima University
      Kanazawa University
  •  Common molecular mechanisms regulating murine breast cancer stem cells and leukemia stem cellsPrincipal Investigator

    • Principal Investigator
      NAKA Kazuhito
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Hiroshima University
      Kanazawa University
  •  TGF-β-FOXOシグナルによるがん幹細胞の制御機構の解明Principal Investigator

    • Principal Investigator
      仲 一仁
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Kanazawa University
  •  Integrative Research on Cancer Microenvironment Network

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Molecular mechanisms maintaining leukemic stem cells by forkhead transcription factor FoxoPrincipal Investigator

    • Principal Investigator
      NAKA Kazuhito
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kanazawa University
  •  正常組織幹細胞を指標とするがん幹細胞特定マウスモデルの構築Principal Investigator

    • Principal Investigator
      仲 一仁
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kanazawa University
  •  C型肝炎ウイルス蛋白質NS5BによるIRF3活性化機構の解析Principal Investigator

    • Principal Investigator
      仲 一仁
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Kanazawa University
      Okayama University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 2008 2006 Other

All Journal Article Presentation Book Patent

  • [Book] Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins (ISBN 978-1-621820-36-9)2017

    • Author(s)
      Naka K., and Hirao A
    • Total Pages
      25
    • Publisher
      CSHL Press
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Book] Methods and Protocols (ISBN 978-1-4939-4011-0)2016

    • Author(s)
      Naka K., and Takihara Y
    • Total Pages
      9
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Book] 造血器腫瘍アトラス2016

    • Author(s)
      仲 一仁
    • Total Pages
      5
    • Publisher
      日本医事新報社
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Book] 白血病学(上)最新の基礎,臨床研究2016

    • Author(s)
      仲 一仁
    • Total Pages
      5
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Book] 血液内科, CML幹細胞を標的とする治療戦略の可能性2015

    • Author(s)
      仲 一仁
    • Total Pages
      6
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Book] 血液内科2015

    • Author(s)
      仲 一仁
    • Total Pages
      6
    • Publisher
      CML幹細胞を標的とする治療戦略の可能性
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Book] 日本臨床 (特集がん幹細胞)2015

    • Author(s)
      仲 一仁
    • Total Pages
      6
    • Publisher
      がん幹細胞のTGF-βシグナル伝達
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Book] 日本臨床 (特集がん幹細胞), がん幹細胞のTGF-βシグナル伝達2015

    • Author(s)
      仲 一仁
    • Total Pages
      6
    • Publisher
      日本臨床社
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Book] CML幹細胞を標的とした新しい治療戦略, がん分子標的治療2014

    • Author(s)
      仲 一仁
    • Total Pages
      7
    • Publisher
      メディカルレビュー
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Book] CML幹細胞を標的とした新しい治療戦略, がん分子標的治療2014

    • Author(s)
      仲 一仁
    • Total Pages
      7
    • Publisher
      メディカルレビュー
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Book] がんの"幹細胞らしさ"と治療抵抗性のメカニズム 29(2)2011

    • Author(s)
      仲一仁, 平尾敦
    • Publisher
      実験医学
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Book] Annual Review血液 20102011

    • Author(s)
      仲一仁, 平尾敦
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Book] がん幹細胞マーカーと分子標的,癌の分子標的治療2008

    • Author(s)
      仲一仁, 平尾敦
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Journal Article] RUNX1 transactivates BCR-ABL1 expression in Philadelphia chromosome positive acute lymphoblastic leukemia2022

    • Author(s)
      Masuda Tatsuya、Maeda Shintaro、Shimada Sae、Sakuramoto Naoya、Morita Ken、Koyama Asami、Suzuki Kensho、Mitsuda Yoshihide、Matsuo Hidemasa、...、Kamikubo Yasuhiko
    • Journal Title

      Cancer Sci

      Volume: 113 Pages: 529-539

    • DOI

      10.1111/cas.15239

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-20H05667, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-20K08756, KAKENHI-PROJECT-21K06909, KAKENHI-PROJECT-21K19353, KAKENHI-PROJECT-21K19405
  • [Journal Article] Pterostilbene downregulates BCR/ABL and induces apoptosis of T315I-mutated BCR/ABL-positive leukemic cells2022

    • Author(s)
      Kawakami Shohei、Tsuma-Kaneko Mitsuyo、Sawanobori Masakazu、Uno Tomoko、Nakamura Yoshihiko、Matsuzawa Hideyuki、Suzuki Rikio、Onizuka Makoto、Yahata Takashi、Naka Kazuhito、Ando Kiyoshi、Kawada Hiroshi
    • Journal Title

      Scientific Reports

      Volume: 12 Pages: 04654-1

    • DOI

      10.1038/s41598-021-04654-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07897, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-21H02767, KAKENHI-PROJECT-21K19353
  • [Journal Article] 慢性骨髄性白血病幹細胞におけるリゾリン脂質代謝2021

    • Author(s)
      仲 一仁
    • Journal Title

      医学のあゆみ

      Volume: 278 Pages: 716-717

    • Data Source
      KAKENHI-PROJECT-21K19353
  • [Journal Article] Role of Lysophospholipid Metabolism in Chronic Myelogenous Leukemia Stem Cells2021

    • Author(s)
      Naka K
    • Journal Title

      Cancers

      Volume: 13 Pages: 3434-3434

    • DOI

      10.3390/cancers13143434

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-21K19353
  • [Journal Article] Statins Enhance the Molecular Response in Chronic Myeloid Leukemia when Combined with Tyrosine Kinase Inhibitors2021

    • Author(s)
      Jang H-J*, Woo YM*, Naka K*(*contributed equally ), Park J-H, Han H-J, Kim H-J, Kim S-H, Ahn JS, KimTH, Kimura S, Zarabi S, Lipton JH, Minden MD, Jung CW, Kim H-J, Kim J-W, Kim DDH.
    • Journal Title

      Cancers

      Volume: 13 Pages: 5543-5543

    • DOI

      10.3390/cancers13215543

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-21K19353
  • [Journal Article] CML幹細胞研究の最前線2021

    • Author(s)
      仲 一仁
    • Journal Title

      血液内科

      Volume: 82 Pages: 271-277

    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Journal Article] 慢性骨髄性白血病幹細胞におけるリゾリン脂質代謝2021

    • Author(s)
      仲 一仁
    • Journal Title

      医学のあゆみ

      Volume: 278 Pages: 716-717

    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Journal Article] KHDRBS3 promotes multi-drug resistance and anchorage-independent growth in colorectal cancer2021

    • Author(s)
      Ukai S, Sakamoto N, Taniyama D, Harada K, Honma R, Maruyama R, Naka K, Hinoi T, Takakura Y, Shimizu W, Ohdan H, Yasui W
    • Journal Title

      Cancer Science

      Volume: 112 Pages: 1196-1208

    • DOI

      10.1111/cas.14805

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03443, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-18K07017
  • [Journal Article] New routes to eradicating chronic myelogenous leukemia stem cells by targeting metabolism2021

    • Author(s)
      Naka K.
    • Journal Title

      International Journal of Hematology

      Volume: 113 Pages: 648-655

    • DOI

      10.1007/s12185-021-03112-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-21K19353
  • [Journal Article] 慢性骨髄性白血病幹細胞2021

    • Author(s)
      仲 一仁
    • Journal Title

      日本臨床

      Volume: 79 Pages: 1769-1775

    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Journal Article] 慢性骨髄性白血病幹細胞2021

    • Author(s)
      仲 一仁
    • Journal Title

      日本臨床

      Volume: 79 Pages: 1769-1775

    • Data Source
      KAKENHI-PROJECT-21K19353
  • [Journal Article] Molecular biological analysis of 5-FU-resistant gastric cancer organoids; KHDRBS3 contributes to the attainment of features of cancer stem cell2020

    • Author(s)
      Ukai S, Honma R, Sakamoto N, Yamamoto Y, Pham QT, Harada K, Takashima T, Taniyama D, Asai R, Fukada K, Naka K, Tanabe K, Ohdan K, Yasui W
    • Journal Title

      Oncogene

      Volume: 39 Pages: 7265-7278

    • DOI

      10.1038/s41388-020-01492-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03443, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-18K07017
  • [Journal Article] FOXOによるがん幹細胞の制御2020

    • Author(s)
      仲 一仁
    • Journal Title

      医学のあゆみ

      Volume: 275 Pages: 397-403

    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Journal Article] The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells2020

    • Author(s)
      Naka K, Ochiai R, Matsubara E, Kondo C, Yang KM, Hoshii T, Araki M, Araki K, Sotomaru Y, Sasaki K, Mitani K, Kim D-W, Ooshima A, Kim SJ.
    • Journal Title

      Nat. Commun.

      Volume: 11 Pages: 1-15

    • DOI

      10.1038/s41467-020-18491-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08822, KAKENHI-PROJECT-19H03690, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-19H01056
  • [Journal Article] Uc.63+ contributes to gastric cancer progression through regulation of NF-kappaB signaling.2020

    • Author(s)
      Sakamoto N, Sekino Y, Fukada, Pham QT, Honma R, Taniyama D, Ukai S, Takashima T, Hattori T, Naka K, Tanabe K, Ohdan H, Yasui W
    • Journal Title

      Gastric Cancer

      Volume: 23 Pages: 863873-863873

    • DOI

      10.1007/s10120-020-01070-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03443, KAKENHI-PROJECT-20H03517, KAKENHI-PROJECT-18K07017
  • [Journal Article] CML幹細胞の維持におけるSirt1の役割2020

    • Author(s)
      2.仲 一仁
    • Journal Title

      血液内科

      Volume: 80 Pages: 455-460

    • NAID

      40022199215

    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Journal Article] Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells2020

    • Author(s)
      Yahata Takashi、Ibrahim Abd Aziz、Hirano Ken-ichi、Muguruma Yukari、Naka Kazuhito、Hozumi Katsuto、Vaughan Douglas E.、Miyata Toshio、Ando Kiyoshi
    • Journal Title

      Haematologica

      Volume: 105 Pages: 483-494

    • DOI

      10.3324/haematol.2019.230227

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03578, KAKENHI-PROJECT-18K14702
  • [Journal Article] HMGCLL1 is a predictive biomarker for deep molecular response to imatinib therapy in chronic myeloid leukemia2019

    • Author(s)
      Park J.-H., Woo Y.-M., Youm E., Hamad N., Won H.-H., Naka K., Park E.-J., Park J.-H., Kim H.J., Kim S.-H., Kim H., Ahn J.-S., Sohn S.-K., Moon J.-H., Jung C.-W., Park S., Lipton J., Kimura S., Jong-Won Kim J.-W., Kim D.
    • Journal Title

      Leukemia

      Volume: epub ahead of print Pages: 1439-1450

    • DOI

      10.1038/s41375-018-0321-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03578, KAKENHI-PROJECT-17K19599, KAKENHI-PROJECT-17K09908
  • [Journal Article] Regulation of hematopoiesis and hematological disease by TGF-β family signaling molecules2017

    • Author(s)
      Naka K., and Hirao A.
    • Journal Title

      Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins

      Volume: 9(9) Pages: 839-863

    • DOI

      10.1101/cshperspect.a027987

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19599, KAKENHI-PROJECT-17H03578
  • [Journal Article] Metabolic regulation specific to leukemia stem cells2017

    • Author(s)
      仲 一仁
    • Journal Title

      Jpn. J. Clin. Hematol.

      Volume: 58 Issue: 10 Pages: 1818-1827

    • DOI

      10.11406/rinketsu.58.1818

    • NAID

      130006132648

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19599, KAKENHI-PROJECT-17H03578
  • [Journal Article] Transcriptome sequencing of hematopoietic stem cells and chronic myelogenous leukemia stem cells.2016

    • Author(s)
      Kim J., Kim S.J., Naka K.
    • Journal Title

      Genomics Data.

      Volume: 7 Pages: 57-59

    • DOI

      10.1016/j.gdata.2015.11.017

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670135, KAKENHI-PROJECT-26290038
  • [Journal Article] Novel oral transforming growth factor-b signaling inhibitor EW-7197 eradicates CML-nitiating cells.2016

    • Author(s)
      Naka K, Ishihara K, Jomen Y, Jin CH, Kim DH, Gu YK, Jeong ES, Li S, Krause DS, Kim DW, Bae E, Takihara Y, Hirao A, Oshima H, Oshima M, Ooshima A, Sheen YY, Kim SJ, Kim DK.
    • Journal Title

      Cancer Science

      Volume: 107 Pages: 140-148

    • DOI

      10.1111/cas.12849

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15H02362, KAKENHI-PROJECT-25430107, KAKENHI-PROJECT-26670135, KAKENHI-PROJECT-26290038, KAKENHI-PROJECT-16K07111
  • [Journal Article] Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance.2016

    • Author(s)
      MatsushitaT, Huu DL, Hamaguchi Y, Hasegawa M, Naka K, Hirao A, Muramatsu M, Takehara K, Fujimoto M.
    • Journal Title

      J Allergy Clin Immunol.

      Volume: 印刷中 Pages: 1170-1182

    • DOI

      10.1016/j.jaci.2015.12.1319

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15H04885, KAKENHI-PROJECT-26290038
  • [Journal Article] New hope for chronic myelogenous leukemia patients: dasatinib offers better efficacy with shorter treatment.2016

    • Author(s)
      Naka K., Ichinohe T.
    • Journal Title

      Stem Cell Investigation

      Volume: 3 Pages: 19-19

    • DOI

      10.21037/sci.2016.05.05

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Journal Article] Homozygous Deletions at 3p22, 5p14, 6q15, and 9p21 Result in Aberrant Expression of Tumor Suppressor Genes in Gastric Cancer.2015

    • Author(s)
      Lee B., Yoon K.Y., Lee S.H., Kang J.M., Kim J.I., Shim S.H., Kim H.-M., Song S.H., Naka K., Kim A.K., Yang H.-K., Kim S.J.
    • Journal Title

      Genes, Chromosomes and Cancer.

      Volume: 54 Pages: 142-155

    • DOI

      10.1002/gcc.22226

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670135, KAKENHI-PROJECT-26290038
  • [Journal Article] Dipeptide species regulate p38MAPK-Smad3 signaling to maintain chronic myelogenous leukaemia stem cells.2015

    • Author(s)
      Naka K, Jomen Y, Ishihara K, Kim J, Ishimoto T, Bae E, Mohney R, Stirdivant SM, Oshima H, Oshima M, Kim DW, Nakauchi H, Takihara Y, Kato Y, Ooshima A, Kim SJ.
    • Journal Title

      Nat. Commun.

      Volume: 6 Pages: 8039-8039

    • DOI

      10.1038/ncomms9039

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15000, KAKENHI-PROJECT-15H02362, KAKENHI-PROJECT-15J03940, KAKENHI-PROJECT-25430107, KAKENHI-PROJECT-26670135, KAKENHI-PROJECT-26290038
  • [Journal Article] Epigenetic circumvention of EGFR-TKI resistance due to BIM deletion polymorphism by HDAC inhibitor and EGFR-TKI2013

    • Author(s)
      Nakagawa T, Yano S, et al.
    • Journal Title

      Cancer Res

      Volume: 73 Pages: 2428-2434

    • DOI

      10.1158/0008-5472.can-12-3479

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-25860638, KAKENHI-PROJECT-25860640, KAKENHI-ORGANIZER-22112001
  • [Journal Article] The novel metastasis promoter Merm1/Wbscr22 enhances tumor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosis.2011

    • Author(s)
      Nakazawa Y, Fujita N, et al.
    • Journal Title

      Cancer Research

      Volume: 71 Pages: 1146-1155

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Journal Article] Persistent vascular normalization as an alternative goal of anti-angiogenic cancer therapy2011

    • Author(s)
      Nakazawa Y, Fujita N, et al
    • Journal Title

      Cancer Sci.

      Volume: 102 Pages: 1253-1256

    • DOI

      10.1111/j.1349-7006.2011.02058.x

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112008, KAKENHI-PROJECT-22650238, KAKENHI-PUBLICLY-23113707, KAKENHI-PROJECT-23227004, KAKENHI-PROJECT-23701107
  • [Journal Article] Suppression of glioma-initiating cell self-renewal by NKX2.2.2011

    • Author(s)
      Muraguchi T., Tanaka S., Yamada D., Tamase A., Nakada M., Nakamura H., Hoshii T., Ooshio T., Tadokoro Y., Naka K., Ino Y., Todo T., Kuratsu J., Saya H., Hamada J., Hirao A.
    • Journal Title

      Cancer Res. 71(3)

      Pages: 1135-1145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Journal Article] TGF-β-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.2010

    • Author(s)
      Naka K., Hoshii T., Muraguchi T., Tadokoro Y., Ooshio T., Kondo Y., Nakao S., Motoyama N., Hirao A.
    • Journal Title

      Nature 463(7281)

      Pages: 676-680

    • NAID

      40018725961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Journal Article] A novel therapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic mveloid leukemia stem cells2010

    • Author(s)
      Naka K., Hoshii T., Hirao A
    • Journal Title

      Cancer Science

      Volume: 101 Pages: 1577-1581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Journal Article] A novel therapeutic approach to eradicate tyrosine kinase inhibitor resistant chronic myeloid leukemia stem cells.2010

    • Author(s)
      Naka K., Hoshii T., Hirao A.
    • Journal Title

      Cancer Science. 101(7)

      Pages: 1577-1581

    • NAID

      10026594276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Journal Article] TGF-β-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia.2010

    • Author(s)
      Naka K., Hoshii T., Hirao A., 他
    • Journal Title

      Nature 463

      Pages: 676-680

    • NAID

      40018725961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Journal Article] Identification of tumor-initiating cells responsible for invasiveness in a genetically homogeneous, highly aggressive brain tumor.2009

    • Author(s)
      Tamase A., Muraguchi T., Naka K., Hirao A., 他
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 106

      Pages: 17163-17168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Journal Article] Identification of stem cells during prepubertal spermatogenesis via monitoring of nucleostemin promoter activity.2008

    • Author(s)
      大村昌子, 仲一仁, 平尾敦, 他
    • Journal Title

      Stem Cells 26

      Pages: 3237-3246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Journal Article] Hepatitis C virus NS5B delays cell cycle progression by inducing IFN-β via Toll-like receptor 3 signaling pathway without replicating viral genomes2006

    • Author(s)
      Naka, K., Dansako, H., Kobayashi N., Ikdeda M., Kato N.
    • Journal Title

      Virology (印刷中)

    • Data Source
      KAKENHI-PROJECT-16790273
  • [Patent] 新規アミノピラゾール誘導体2019

    • Inventor(s)
      澤 匡明, 森山 英樹, 大本 弘志, 仲 一仁
    • Industrial Property Rights Holder
      カルナバイオサイエンス株式会社, 国立大学法人広島大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Patent] 5FU耐性癌治療用医薬組成物2019

    • Inventor(s)
      安井 弥,坂本直也,鵜飼翔一,本間りりの,仲 一仁
    • Industrial Property Rights Holder
      国立大学法人広島大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-167410
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Patent] 新規アミノピラゾール誘導体2018

    • Inventor(s)
      澤 匡明, 森山 英 樹, 大本 弘志, 仲 一仁
    • Industrial Property Rights Holder
      カルナバイオサ イエンス株式会 社, 広島大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-243575
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Patent] 新規アミノピラゾール誘導体2018

    • Inventor(s)
      澤 匡明, 森山 英樹, 大本 弘志, 仲 一仁
    • Industrial Property Rights Holder
      カルナバイオサイエンス株式会社, 広島大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-243575
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Patent] 慢性骨髄性白血病治療剤2015

    • Inventor(s)
      仲 一仁, 定免由枝,石原薫理
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-020709
    • Filing Date
      2015-02-04
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Patent] 慢性骨髄性白血病治療剤2015

    • Inventor(s)
      仲 一仁, 定免由枝,石原薫理
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-020709
    • Filing Date
      2015-02-04
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Patent] 慢性骨髄性白血病治療剤2015

    • Inventor(s)
      仲 一仁
    • Industrial Property Rights Holder
      広島大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-075195
    • Filing Date
      2015-04-01
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Patent] 慢性骨髄性白血病治療剤2015

    • Inventor(s)
      仲 一仁
    • Industrial Property Rights Holder
      広島大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-075195
    • Filing Date
      2015-04-01
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Patent] 白血病治療剤及び該治療剤の新規なスクリーニング2009

    • Inventor(s)
      平尾敦, 仲一仁
    • Industrial Property Rights Holder
      平尾敦, 仲一仁, 金沢大学
    • Industrial Property Number
      2009-134714
    • Acquisition Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Patent] 白血病治療剤及び該治療剤の新規なスクリーニング2009

    • Inventor(s)
      平尾敦, 仲一仁
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2009-134714
    • Filing Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] リゾリン脂質代謝によるCML幹細胞の制御メカニズム2021

    • Author(s)
      仲 一仁
    • Organizer
      第5回放射線災害・医科学研究拠点カンファランス
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] The lysophospholipid metabolism enzyme Gdpd3 maintains chronic myelogenous leukemia stem cells2021

    • Author(s)
      Kazuhito Naka
    • Organizer
      FASEB Science Research Conference "The Lysophospholipid and Related Mediators Conference: From Bench to Clinic, Malahide, Ireland
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19353
  • [Presentation] Lysophospholipid metabolism is essential for the maintenance of chronic myelogenous leukemia stem cells2021

    • Author(s)
      Kazuhito Naka, Ryosuke Ochiai, Eriko Matsubara, Chie Kondo, Kyung-Min Yang, Akira Ooshima and Seong-Jin Kim
    • Organizer
      The 5th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] Lipid Metabolism Specific to CML Stem Cells2021

    • Author(s)
      Kazuhito Naka
    • Organizer
      The 12th Japanese Society of Hematology International Symposium 2021, Kamakura, Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19353
  • [Presentation] Lysophospholipid metabolism is essential for the maintenance of chronic myelogenous leukemia stem cells2021

    • Author(s)
      Kazuhito Naka, Ryosuke Ochiai, Eriko Matsubara, Chie Kondo, Kyung-Min Yang, Akira Ooshima and Seong-Jin Kim,
    • Organizer
      The 5th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] The lysophospholipid metabolism enzyme Gdpd3 maintains chronic myelogenous leukemia stem cells2021

    • Author(s)
      Kazuhito Naka
    • Organizer
      23rd Annual John Goldman E-Conference on Chronic Myeloid Leukemia: Biology and Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19353
  • [Presentation] CML幹細胞の脂質代謝メカニズム2021

    • Author(s)
      仲 一仁
    • Organizer
      第1回 Basic and Clinical Researcher 支援セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] リゾリン脂質代謝によるCML幹細胞の制御メカニズム2021

    • Author(s)
      仲 一仁
    • Organizer
      第5回放射線災害・医科学研究拠点カンファランス
    • Data Source
      KAKENHI-PROJECT-21K19353
  • [Presentation] The lysophospholipid metabolism enzyme Gdpd3 maintains chronic myelogenous leukemia stem cells2021

    • Author(s)
      Kazuhito Naka
    • Organizer
      23rd Annual John Goldman E-Conference on Chronic Myeloid Leukemia: Biology and Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] Lipid Metabolism Specific to CML Stem Cells2021

    • Author(s)
      Kazuhito Naka
    • Organizer
      The 12th Japanese Society of Hematology International Symposium 2021, Kamakura, Japan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] The lysophospholipid metabolism enzyme Gdpd3 maintains chronic myelogenous leukemia stem cells2021

    • Author(s)
      Kazuhito Naka
    • Organizer
      The lysophospholipid metabolism enzyme Gdpd3 maintains chronic myelogenous leukemia stem cells, FASEB Science Research Conference "The Lysophospholipid and Related Mediators Conference, Ireland
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] Lysophospholipid metabolism is essential for the maintenance of chronic myelogenous leukemia stem cells2021

    • Author(s)
      Kazuhito Naka, Ryosuke Ochiai, Eriko Matsubara, Chie Kondo, Kyung-Min Yang, Akira Ooshima and Seong-Jin Kim
    • Organizer
      The 5th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19353
  • [Presentation] CML幹細胞の脂質代謝メカニズム2021

    • Author(s)
      仲 一仁
    • Organizer
      第1回 Basic and Clinical Researcher 支援セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K19353
  • [Presentation] The lysophospholipid metabolism enzyme Gdpd3 maintains chronic myelogenous leukemia stem cells.2020

    • Author(s)
      Kazuhito Naka
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] CML幹細胞の脂質代謝メカニズム2020

    • Author(s)
      仲 一仁
    • Organizer
      島津テクノリサーチWebinar
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] Establishment and molecular biological analysis of 5-FU resistant gastric cancer organoids2020

    • Author(s)
      Shoichi Ukai, Naoya Sakamoto, Ririno Honma, Daiki Taniyama, Quoc Thang Pham, Tsuyoshi Takashima, Kenji Harada, Kazuhito Naka, Kazuaki Tanabe, Hideki Ohdan, Wataru Yasui
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03517
  • [Presentation] Nutrient Supply Specific to CML Stem Cells2019

    • Author(s)
      Kazuhito Naka
    • Organizer
      29th Symposium of the International Association for Comparative Research on Leukemia and Related Diseases
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] PAI-1活性の阻害による慢性骨髄性白血病幹細胞の治療高感受性化2018

    • Author(s)
      八幡崇, Abd Aziz Ibrahim, 仲 一仁,宮田敏男,安藤潔
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] Novel therapeutic strategy targeting nutrient supply specific to chronic myelogenous leukemia stem cells2018

    • Author(s)
      Kazuhito Naka, and Seong-Jin Kim
    • Organizer
      The 9th Japanese Society of Hematology International Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] 幹細胞の栄養・代謝システムを標的とするがん再発治療法の開発2018

    • Author(s)
      仲 一仁
    • Organizer
      大阪府商工労働部平成29年度 創薬シーズ事業化コンペティション
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] Novel therapeutic strategy targeting nutrient supply specific to chronic myelogenous leukemia stem cells2018

    • Author(s)
      Kazuhito Naka, and Seong-Jin Kim
    • Organizer
      The 9th Japanese Society of Hematology International Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] マウスモデルを用いた慢性骨髄性白血病発症におけるIL-27の抗腫瘍効果2018

    • Author(s)
      折井直子,溝口出,長谷川英哲, 義本隆之, 仲一仁
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] PAI-1活性の阻害による慢性骨髄性白血病幹細胞の治療高感受性化2018

    • Author(s)
      八幡崇, Abd Aziz Ibrahim, 仲 一仁,宮田敏男,安藤潔
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] マウスモデルを用いた慢性骨髄性白血病発症におけるIL-27の抗腫瘍効果2018

    • Author(s)
      折井直子,溝口出,長谷川英哲, 義本隆之, 仲一仁
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] 幹細胞の栄養・代謝システムを標的とするがん再発治療法の開発2018

    • Author(s)
      仲 一仁
    • Organizer
      大阪府商工労働部平成29年度 創薬シーズ事業化コンペティション
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] 特別教育講演「代謝を標的とした白血病幹細胞制御」2017

    • Author(s)
      仲 一仁
    • Organizer
      第79回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] Novel therapeutic strategy targeting nutrition specific to CML stem cells2017

    • Author(s)
      仲 一仁
    • Organizer
      Metabolon Seminar ~メタボロミクス・リピドミクスの最前線~
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] CML幹細胞の新しい治療戦略2017

    • Author(s)
      仲 一仁
    • Organizer
      第40回八幡平血液セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] Discovery of novel therapeutics targeting CML stem cells by Duolink technology2017

    • Author(s)
      仲 一仁
    • Organizer
      Scientist Round Table
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] 幹細胞における新しいシグナル伝達研究 (ランチョンセミナー)2017

    • Author(s)
      仲 一仁
    • Organizer
      第40回日本神経科学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] CML幹細胞の新しい治療戦略 ~Novel therapeutic strategy for eliminating CML stem cells~2017

    • Author(s)
      仲 一仁
    • Organizer
      BMS CML Symposium 2017 in Hiroshima
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] CML幹細胞の新しい治療戦略2017

    • Author(s)
      仲 一仁
    • Organizer
      Hematology Seminar in KAGOSHIMA
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] Novel therapeutic strategy targeting nutrition specific to CML stem cells2017

    • Author(s)
      仲 一仁
    • Organizer
      Metabolon Seminar ~メタボロミクス・リピドミクスの最前線~
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] Novel therapeutic strategy targeting nutrient supply of chronic myelogenous leukemia stem cells2017

    • Author(s)
      Kazuhito Naka, Yoshihiro Takihara, Ichinohe Tatsuo, Eisuke Hida, Yukio Kato, Wataru Yasui, and Seong-Jin Kim
    • Organizer
      Global Academic Programs 2017 Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] 特別教育講演「代謝を標的とした白血病幹細胞制御」2017

    • Author(s)
      仲 一仁
    • Organizer
      第79回日本血液学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] CML幹細胞の新しい治療戦略 ~Novel therapeutic strategy for eliminating CML stem cells~2017

    • Author(s)
      仲 一仁
    • Organizer
      BMS CML Symposium 2017 in Hiroshima
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] Discovery of novel therapeutics targeting CML stem cells by Duolink technology2017

    • Author(s)
      仲 一仁
    • Organizer
      Scientist Round Table
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] CML幹細胞の栄養メカニズム2017

    • Author(s)
      仲 一仁
    • Organizer
      日本がん分子標的治療学会第12回トランスレーショナルリサーチ (TR) ワークショップ
    • Place of Presentation
      東京
    • Year and Date
      2017-01-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] Novel therapeutic strategy targeting nutrient supply of chronic myelogenous leukemia stem cells2017

    • Author(s)
      Kazuhito Naka, and Wataru Yasui
    • Organizer
      Special Session TMP (Translational Molecular Pathology) Division of Pathology Meeting Series
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] CML幹細胞の新しい治療戦略2017

    • Author(s)
      仲 一仁
    • Organizer
      Hematology Seminar in KAGOSHIMA
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] Duolink PLA技術を用いたCML幹細胞のシグナル伝達研究と前臨床試験への応用 (ランチョンセミナー)2017

    • Author(s)
      仲 一仁
    • Organizer
      第76回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] Novel therapeutic strategy targeting nutrient supply of chronic myelogenous leukemia stem cells2017

    • Author(s)
      Kazuhito Naka, and Wataru Yasui
    • Organizer
      Special Session TMP (Translational Molecular Pathology) Division of Pathology Meeting Series
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] 幹細胞における新しいシグナル伝達研究 (ランチョンセミナー)2017

    • Author(s)
      仲 一仁
    • Organizer
      第40回日本神経科学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] CML幹細胞の新しい治療戦略2017

    • Author(s)
      仲 一仁
    • Organizer
      第40回八幡平血液セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03578
  • [Presentation] Novel therapeutic strategy targeting nutrient supply of chronic myelogenous leukemia stem cells2017

    • Author(s)
      Kazuhito Naka, Yoshihiro Takihara, Ichinohe Tatsuo, Eisuke Hida, Yukio Kato, Wataru Yasui, and Seong-Jin Kim
    • Organizer
      Global Academic Programs 2017 Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] Duolink PLA技術を用いたCML幹細胞のシグナル伝達研究と前臨床試験への応用 (ランチョンセミナー)2017

    • Author(s)
      仲 一仁
    • Organizer
      第76回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K19599
  • [Presentation] CML幹細胞をターゲットとする新しい治療戦略2016

    • Author(s)
      仲 一仁
    • Organizer
      第3回次世代がんインフォマティクス研究会
    • Place of Presentation
      岡山市
    • Year and Date
      2016-06-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] Nutrient Supply Essential for the Maintenance of CML Stem Cells (Poster)2016

    • Author(s)
      Kazuhito Naka, Yoshihiro Takihara, Yukio Kato, Hiromitsu Nakauchi, Akira Ooshima, and Seong-Jin Kim
    • Organizer
      広島大学&テキサス大学MDアンダーソンがんセンター合同シンポジウム
    • Place of Presentation
      広島市
    • Year and Date
      2016-07-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] Novel therapeutic strategy targeting TGF-β-Smad3 signaling in CML stem cells2016

    • Author(s)
      Kazuhito Naka
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-10-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] Dipeptide species regulate nutrient signalling essential for the maintenance of chronic myelogenous leukaemia stem cells (Poster)2016

    • Author(s)
      Kazuhito Naka, Akira Ooshima, Yukio Kato, Yoshihiro Takihara, and Seong-Jin Kim
    • Organizer
      Keystone Symposia, Stem Cells and Cancer
    • Place of Presentation
      コロラド州・ブリッケンリッジ (米国)
    • Year and Date
      2016-03-06
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Presentation] Dipeptide species regulate nutrient signalling essential for the maintenance of chronic myelogenous leukaemia stem cells (Poster)2016

    • Author(s)
      Kazuhito Naka, Akira Ooshima, Yukio Kato, Yoshihiro Takihara, and Seong-Jin Kim
    • Organizer
      Keystone Symposia, Stem Cells and Cancer
    • Place of Presentation
      Breckenridge, CO, USA
    • Year and Date
      2016-03-06
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] Nutrient Supply Essential for the Maintenance of CML Stem Cells2016

    • Author(s)
      Kazuhito Naka, Yoshihiro Takihara, Yukio Kato, Hiromitsu Nakauchi, Akira Ooshima, and Seong-Jin Kim
    • Organizer
      第14回幹細胞シンポジウム
    • Place of Presentation
      兵庫県南淡町
    • Year and Date
      2016-05-20
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] CML幹細胞をターゲットとする新しい治療戦略 (ランチョンセミナー)2015

    • Author(s)
      仲 一仁
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      ANAクラウンプラザホテル金沢,金沢市
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Presentation] がん幹細胞の抗がん剤抵抗性メカニズム2015

    • Author(s)
      仲 一仁
    • Organizer
      第18回癌と骨病変研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-11-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] CML幹細胞をターゲットとする新しい治療戦略 (ワークショップ)2015

    • Author(s)
      仲 一仁, 瀧原義宏
    • Organizer
      第38回分子生物学会年会
    • Place of Presentation
      神戸国際会議場,神戸市
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Presentation] CML幹細胞をターゲットとする新しい治療戦略 (ランチョンセミナー)2015

    • Author(s)
      仲 一仁
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県 金沢市
    • Year and Date
      2015-10-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] CML幹細胞をターゲットとする新しい治療戦略 (ワークショップ)2015

    • Author(s)
      仲 一仁, 瀧原義宏
    • Organizer
      第38回分子生物学会年会
    • Place of Presentation
      兵庫県 神戸市
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] がん幹細胞の抗がん剤抵抗性メカニズム (指定演題)2015

    • Author(s)
      仲 一仁
    • Organizer
      第18回癌と骨病変研究会
    • Place of Presentation
      千代田放送会館,東京
    • Year and Date
      2015-11-13
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Presentation] The Novel Oral TGFβ Signaling Inhibitor Targets Chronic Myeloid Leukemia Stem Cells2014

    • Author(s)
      Kazuhito Naka, Dong-Hyun Kim, Shaoguang Li, Yhun Yhong Sheen, Akira Oshima, Seong-Jin Kim, and Dae-Kee Kim
    • Organizer
      Sixteenth Annual John Goldman Conference on Chronic Myeloid Leukemia Biology and Therapy
    • Place of Presentation
      Philadelphia, PA, USA
    • Year and Date
      2014-09-08
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Presentation] TGF-β-FOXOシグナルによる白血病幹細胞の治療抵抗性機構2010

    • Author(s)
      仲一仁
    • Organizer
      第16回血液科学セミナー
    • Place of Presentation
      京王プラザホテル(東京都新宿区)(招待講演)
    • Year and Date
      2010-10-24
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] TGF-β-FOXOシグナルによる白血病幹細胞の抗がん剤抵抗性機構の解析2010

    • Author(s)
      仲一仁, 平尾敦
    • Organizer
      第19回日本がん転移学会
    • Place of Presentation
      金沢市文化ホール(石川県金沢市)(招待講演)
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Molecular Mechanism Regulating Foxo In Leukemia Initiating Cells of Chronic Myeloid Leukemia.2010

    • Author(s)
      Kazuhito Naka, Takayuki Hoshii, Yuko Tadokoro, Takako Ooshio, Yukio Kondo, Shinji Nakao, Noboru Motoyama, Atsushi Hirao
    • Organizer
      The 52^<nd> American Society of Hematology Annual meeting and exposition
    • Place of Presentation
      Orange County Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Molecular Mechanism Regulating Foxo In Leukemia Initiating Cells of Chronic Myeloid Leukemia.2010

    • Author(s)
      仲一仁, 他7名, 1番目
    • Organizer
      アメリカ血液学会
    • Place of Presentation
      Orange County Convention Center(アメリカ,オーランド)
    • Year and Date
      2010-12-06
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Molecular mechanism regulating FOXO in leukemia initiating cells of chronic myeloid leukemia.2010

    • Author(s)
      Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi, Yoko Tadokoro, Takako Ooshio, Yukio Kondo, Shinji Nakao, Noboru Motoyama, Atsushi Hirao
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜国立横浜国際会議場(神奈川県)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] TGF-β-FOXOシグナルによる白血病幹細胞の治療抵抗性機構2010

    • Author(s)
      仲一仁
    • Organizer
      第16回血液科学セミナー
    • Place of Presentation
      京王プラザホテル(東京都)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Molecular mechanism regulating FOXO in leukemia initiating cells of chronic myeloid leukemia.2010

    • Author(s)
      仲一仁, 他8名, 1番目
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Foxo3a is essential for survival of leukemia-initiating cells in chronic myeloid leukemia.2010

    • Author(s)
      Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi, Yuko Tadokoro, Takako Ooshio, Noboru Motoyama, Masanobu Oshima, Atsushi Hirao
    • Organizer
      American Association for Cancer Research 101st Annual meeting
    • Place of Presentation
      Walter E.Washington Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Analyses of molecular mechanism regulating FOXO in leukemia initiating cells of chronic myeloid leukemia.2010

    • Author(s)
      仲一仁, 他6名, 1番目
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] 白血病幹細胞の抗がん剤抵抗性機構の解析2010

    • Author(s)
      仲一仁, 平尾敦
    • Organizer
      第19回日本癌病態治療研究会
    • Place of Presentation
      東京ステーションコンファレンス(東京都)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Foxo3a is essential for survival of leukemia-initiating cells in chronic myeloid leukemia2010

    • Author(s)
      仲一仁, 他7名, 1番目
    • Organizer
      アメリカがん学会
    • Place of Presentation
      Walter E. Washington Convention Center (アメリカ, ワシントンDC)
    • Year and Date
      2010-04-20
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] TGF-β-FOXOシグナルによる白血病幹細胞の抗がん剤抵抗性機構の解析2010

    • Author(s)
      仲一仁, 平尾敦
    • Organizer
      第19回日本がん転移学会
    • Place of Presentation
      金沢市文化ホール(石川県)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Analyses of molecular mechanism regulating FOXO in leukemia initiating cells of chronic myeloid leukemia.2010

    • Author(s)
      Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi, Yoko Tadokoro, Takako Ooshio, Noboru Motoyama, Atsushi Hirao
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Foxo3a is essential for maintenance of chronic myelogenous leukemia-initiating cells.2009

    • Author(s)
      Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi, Yoko Tadokoro, Takako Ooshio, Noboru Motoyama, Atsushi Hirao
    • Organizer
      第7回幹細胞シンポジウム
    • Place of Presentation
      泉ガーデンギャラリー(東京都)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Foxo3a is essential for survival of chronic myeloid leukemia-initiating cells.2009

    • Author(s)
      Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi, Takako Ooshio, Noboru Motoyama, Atsushi Hirao
    • Organizer
      7^<th> International Society of Stem Cell Research
    • Place of Presentation
      Centre Convencions Internacional Barcelona (Spain)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Foxo3a is essential for maintenance of chronic myelogenous leukemia-initiating cells.2009

    • Author(s)
      Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi, Yoko Tadokoro, Takako Ooshio, Noboru Motoyama, Atsushi Hirao
    • Organizer
      第71回日本血液学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Foxo3a is essential for maintenance of chronic myelogenous leukemia-initiating cells.2009

    • Author(s)
      Kazuhito Naka, Takayuki Hoshii, Teruyuki Muraguchi, Yoko Tadokoro, Takako Ooshio, Noboru Motoyama, Atsushi Hirao
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜国立横浜国際会議場(神奈川県)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Foxo3a is essential for maintenance of chronic myelogenous leukemia-initiating cells.2009

    • Author(s)
      仲一仁・平尾敦, 他
    • Organizer
      第71回日本血液学会総会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Foxo3a is essential for maintenance of chronic myelogenous leukemia-initiating cells.2009

    • Author(s)
      仲一仁・平尾敦, 他
    • Organizer
      第68回日本癌学会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Nucleostemin-GFPレポークシステムによる白血病幹細胞の同定2008

    • Author(s)
      仲一仁, 平尾敦, 他
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都市
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] Nucleostemin-GFPレポーターシステムによる白血病幹細胞の同定2008

    • Author(s)
      仲一仁, 平尾敦, 他
    • Organizer
      第67回日本癌学会
    • Place of Presentation
      名古屋市
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-20590394
  • [Presentation] The Novel Oral TGFβ Signaling Inhibitor Targets Chronic Myeloid Leukemia Stem Cells

    • Author(s)
      Kazuhito Naka, Dong-Hyun Kim, Shaoguang Li, Yhun Yhong Sheen, Akira Oshima, Seong-Jin Kim, and Dae-Kee Kim
    • Organizer
      Sixteen Annual John Goldman Conference on Chronic Myeloid Leukemia Biology and Therapy
    • Place of Presentation
      Philadelphia, PA, USA
    • Year and Date
      2014-09-03 – 2014-09-08
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] Novel Therapeutic Strategy for Targeting CML stem cells

    • Author(s)
      仲 一仁
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県,横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Presentation] TGFβ Signaling Inhibitor eradicates CML Stem Cells

    • Author(s)
      Kazuhito Naka, Kaori Ishihara, Yoshie Jomen
    • Organizer
      Fourth Joint International Symposium on TGF-β and Cancer
    • Place of Presentation
      つくば国際会議場(茨城県,つくば市)
    • Year and Date
      2015-01-12 – 2015-01-13
    • Data Source
      KAKENHI-PROJECT-26670135
  • [Presentation] TGF-β signaling inhibitor eradicates chronic myelogenous leukemia stem cells

    • Author(s)
      仲 一仁、石原薫理、定免由枝
    • Organizer
      がん研究分野の特性等を踏まえた支援活動・公開シンポジウム
    • Place of Presentation
      学術総合センター(東京都千代田区)
    • Year and Date
      2015-01-27 – 2015-01-28
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] Novel Therapeutic Strategy for Targeting CML stem cells (International Session)

    • Author(s)
      仲 一仁
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県,横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] TGFβ Signaling Inhibitor eradicates CML Stem Cells

    • Author(s)
      Kazuhito Naka, Kaori Ishihara, Yoshie Jomen
    • Organizer
      Fourth Joint International Symposium on TGF-beta and Cancer
    • Place of Presentation
      つくば国際会議場(茨城県,つくば市)
    • Year and Date
      2015-01-12 – 2015-01-13
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] TGFβ Signaling Inhibitor eradicates CML Stem Cells

    • Author(s)
      Kazuhito Naka, Kaori Ishihara, Yoshie Jomen
    • Organizer
      平成26年度 新学術領域研究 「がん研究分野の特性等を踏まえた支援活動」冬期公開シンポジウム
    • Place of Presentation
      一橋記念講堂(東京都,千代田区)
    • Year and Date
      2015-01-26 – 2015-01-27
    • Data Source
      KAKENHI-PROJECT-26290038
  • [Presentation] TGFβ Signaling Inhibitor eradicates CML Stem Cells

    • Author(s)
      Kazuhito Naka, Kaori Ishihara, Yoshie Jomen
    • Organizer
      平成26年度 新学術領域研究 「がん研究分野の特性等を踏まえた支援活動」冬期公開シンポジウム
    • Place of Presentation
      一橋記念講堂(東京都,千代田区)
    • Year and Date
      2015-01-26 – 2015-01-27
    • Data Source
      KAKENHI-PROJECT-26670135
  • 1.  Hayashi Tetsutaro (60612835)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  Shinmei Shunsuke (70749936)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  松原 昭郎 (10239064)
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  • 4.  亭島 淳 (20397962)
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  • 5.  坂本 直也 (20571798)
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    # of Collaborated Products: 4 results
  • 6.  MIYAZONO Kohei (90209908)
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  • 7.  AKIYAMA Tetsu (70150745)
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  • 8.  FUJITA Naoya (20280951)
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    # of Collaborated Products: 2 results
  • 9.  TAKAKURA Nobuyuki (80291954)
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  • 10.  SATO Yasufumi (50178779)
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    # of Collaborated Products: 1 results
  • 11.  YANO Seiji (30294672)
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    # of Collaborated Products: 1 results
  • 12.  KONDOH Shinae (40314182)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MINAMI Takashi (00345141)
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  • 14.  HEISSIG Beate (30372931)
    # of Collaborated Projects: 1 results
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  • 15.  TABATA Yasuhiko (50211371)
    # of Collaborated Projects: 1 results
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  • 16.  ABURATANI Hiroyuki (10202657)
    # of Collaborated Projects: 1 results
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  • 17.  MANO Hiroyuki (90240704)
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  • 18.  HARA Eiji (80263268)
    # of Collaborated Projects: 1 results
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  • 19.  井上 省吾 (90457177)
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  • 20.  安井 弥 (40191118)
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  • 21.  GORIKI akihiro
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    # of Collaborated Products: 0 results
  • 22.  Black Peter C
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  Oo Htoo Zarni
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  NAKAZAWA Youya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  YAHATA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  OSHIMA Hiroko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 27.  YAMADA Tadaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  TAKEUCHI Shinji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  HOSHII Takayuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  Tadokoro Yuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  Kobayashi Masahiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  Ueno Masaya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  MATSUSHITA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  IBRAHIM Abd Aziz
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  松尾 英将
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  今井 陽一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  滝田 順子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  木村 晋也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 39.  新井 洋由
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  高木 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  川田 浩志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  安藤 潔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  鈴木 利貴央
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  平尾 敦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 45.  大島 正伸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 46.  三谷 絹子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  佐々木 光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  荒木 喜美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  外丸 祐介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  藤本 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  加藤 将夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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