KIKUCHI Kunio 菊池邦生

Researcher Number	70374676
Affiliation (based on the past Project Information) *help	2015: 日本医科大学, 医学部, 講師 2011 – 2013: 日本医科大学, 医学部, 講師 2009 – 2010: 日本医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology / Digestive surgery
Keywords	Principal Investigator マイクロRNA / microRNA / 胎盤 / 産科学 Except Principal Investigator microRNA / マイクロRNA / 栄養 / 免疫 / 小胞輸送 / 細胞・組織 … More / micro RNA / 妊娠高血圧腎症 / 胎盤 / 妊娠 / 産科学 / 胆管癌 / 肝胆道 / 癌 / 胆道 / 外科学 / 生殖医学 / 卵胞顆粒膜細胞 / 卵巣 Less

Elucidation of the roles of placental microRNAs in the pathogenesis of preeclampsia and identification of novel prognostic factors for preeclampsia
- Principal Investigator
  
  TAKIZAWA Toshihiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nippon Medical School
IgG transport mechanism of Fc gamma RIIb-containing compartments across the placental barrier
- Principal Investigator
  
  ISHIKAWA Tomoko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Ochanomizu University
Expression and functional analysis of miRNAs in human placenta:molecular and cellar research of IUGRPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Kunio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nippon Medical School
Profiling and functional analyses of microRNAs in human intrahepatic cholangiocarcinoma
- Principal Investigator
  
  ISHIKAWA Tomoko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Profiling and functional analysis of microRNAs in follicular granulosa cells and their clinical application
- Principal Investigator
  
  TAKESHITA Toshiyuki, 羅善順
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nippon Medical School

All 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] 臨床婦人科産科2011
- Author(s)
  菊池邦生、石橋宰、竹下俊行、瀧澤俊広
- Data Source
  KAKENHI-PROJECT-22791553
[Journal Article] Placenta-specific miRNA (miR-512-3p) targets PPP3R1 encoding the calcineurin B regulatory subunit in BeWo cells2014
- Author(s)
  Ryuhei Kurashina, Kunio Kikuchi, Jun Iwaki, Hiroshi Yoshitake, Toshiyuki Takeshita, Toshihiro Takizawa
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 40 Issue: 3 Pages: 650-660
- DOI
  10.1111/jog.12217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390383, KAKENHI-PROJECT-24592609
[Journal Article] Relationship between altered expression levels of MIR21, MIR143, and MIR205 and clinicopathologic features of esophageal squamous cell carcinoma2011
- Author(s)
  Akagi I, Miyashita M, Ishibashi O, Mishima T, Makino H, Nomu Uchida E, Takizawa T.
- Journal Title
  
  Dis Esophagus
  
  Volume: 24(7) Issue: 7 Pages: 523-530
- DOI
  10.1111/j.1442-2050.2011.01177.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591714, KAKENHI-PROJECT-22791553
[Journal Article] SnoN/SKIL modulates proliferationthrough control of hsa-miR-720 transcription in esophageal cancer cells.2011
- Author(s)
  Eriko Shinozuka, Masao Miyashita, Yoshiaki Mizuguchi, Ichiro Akagi, Kunio Kikuchi, Hiroshi Makino, Takeshi Matsutani, Nobutoshi Hagiwara, Tsutomu Nomura, Eiji Uchida, Toshihiro Takizawa.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 430(1) Issue: 1 Pages: 101-106
- DOI
  10.1016/j.bbrc.2012.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791553, KAKENHI-PROJECT-24590559
[Journal Article] 絨毛細胞におけるマイクロRNA2011
- Author(s)
  菊池邦生
- Journal Title
  
  臨床婦人科産科
  
  Volume: 65 Pages: 254-259
- Data Source
  KAKENHI-PROJECT-22791553
[Journal Article] Genes that Integrate multiple adipogenic signaling pathways in human mesenchymal stem cells2011
- Author(s)
  Ito T, Tsuruta S, Tomita K, Kikuchi K, Yokoi T, Aizawa Y
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 409(4) Issue: 4 Pages: 786-791
- DOI
  10.1016/j.bbrc.2011.05.089
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113505, KAKENHI-PROJECT-22791553
[Journal Article] 絨毛と胎盤をめぐる新知見【絨毛研究最前線4】絨毛細胞におけるマイクロRNA2011
- Author(s)
  菊池邦生, 石橋宰, 竹下俊行, 瀧澤俊広
- Journal Title
  
  臨床婦人科産科
  
  Volume: 65 Pages: 254-259
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] 栄養膜細胞におけるC19MCプロモーター領域のメチル化解析2014
- Author(s)
  高橋宏典, 大口昭英, 桑田知之, 薄井里英, 菊池邦生, 松原茂樹, 鈴木光明, 竹下俊行, 瀧澤俊広
- Organizer
  第22回日本胎盤学会学術集会
- Place of Presentation
  京都大学芝蘭会館　（京都)
- Year and Date
  2014-10-03
- Data Source
  KAKENHI-PROJECT-24390383
[Presentation] 胎盤特異的miRNA，miR-512-3pはPPP3R1を標的としている2013
- Author(s)
  倉品隆平、菊池邦生、吉武洋、瀧澤俊広、竹下俊行
- Organizer
  第65回日本産科婦人科学会学術講演会
- Place of Presentation
  札幌プリンスホテル（札幌市、北海道)
- Data Source
  KAKENHI-PROJECT-24390383
[Presentation] MicroRNAを介した絨毛栄養膜細胞による絨毛外栄養膜細胞の浸潤制御2013
- Author(s)
  高橋宏典、菊池邦生、大口昭英、松原茂樹、桑田知之、薄井里英、松本久宣、佐藤幸保、藤原浩、岡本愛光、瀧澤俊広、鈴木光明
- Organizer
  第65回日本産科婦人科学会学術講演会
- Place of Presentation
  ロイトン札幌（札幌市、北海道)
- Data Source
  KAKENHI-PROJECT-24390383
[Presentation] 瀧澤俊広胎盤由来のマイクロRNAは妊娠期間中エクソソームを介して母体血球細胞に取り込まれている2012
- Author(s)
  神戸沙織,石田洋一,菊池邦生,大口昭英,松原茂樹,鈴木光明,竹下俊行
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] Methylation profile of C19MC-miRNA CpG island in trophoblast cell lines2012
- Author(s)
  菊池邦生
- Organizer
  IFPA 2012 Hiroshima Meeting
- Place of Presentation
  広島国際会議場(広島県)(招待講演)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-24390383
[Presentation] Circulating placenta-specific miRNAs are delivered to maternal immune cells during pregnancy.2012
- Author(s)
  Saori Kambe, Yoichi Ishida, Kunio Kikuchi, Hiroshi Yoshitake, Akihide Okuchi, Shigeki Matsubara, MitsuakiSuzuki, Shigeru Saito, Toshiyuki Takeshita, Toshihiro Takizawa
- Organizer
  IFPA 2012 Hiroshima Meeting
- Place of Presentation
  広島県広島市
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 胎盤栄養膜における接着因子CD44の浸潤能と発現制御機構の解析2012
- Author(s)
  高橋宏典,菊池邦生,竹下俊行,松原茂樹,鈴木光明,瀧澤俊広
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2012-04-15
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 瀧澤俊広microRNAの網羅的解析手法と生殖免疫学分野での応用2012
- Author(s)
  菊池邦生,アリモハメド,岩城隼,吉武洋,瀧澤敬美,石川源,松原茂樹,竹下俊行
- Organizer
  第27回日本生殖免疫学会総会・学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] Methylation profile of C19MC-miRNA CpG island in trophoblast cell lines2012
- Author(s)
  Kunio Kikuchi, Guangjin Qu, Hironori Takahashi, Tomoyuki Kuwata, Rie Usui, Akihide Ohkuchi, Shan-shun Luo, Shigeki Matsubara, Mitsuaki Suzuki, Toshihiro Takizawa
- Organizer
  IFPA 2012 Hiroshima Meeting
- Place of Presentation
  広島県広島市
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] microRNAの網羅的解析手法と生殖免疫学分野での応用2012
- Author(s)
  菊池邦生
- Organizer
  第27回日本生殖免疫学会総会・学術集会
- Place of Presentation
  大阪医科大学(大阪府)(招待講演)
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-24390383
[Presentation] 胎盤特異的microRNAの発現に関与するCpG配列のメチル化解析2012
- Author(s)
  菊池邦生, 曲光瑾, 羅善順, 瀧澤俊広
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  山梨
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] 食道扁平上皮癌におけるmiRNA発現と臨床病理学的意義の検討2012
- Author(s)
  篠塚恵理子,宮下正夫,水口義昭,赤城一郎,菊池邦生,萩原信敏,松谷毅,牧野浩司,野村務,瀧澤俊広,内田英二
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  千葉県幕張市
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] BeWo-cell-derived miR-517a modulates the expression of PRKG1 in Jurkat cells via Exosomes.2012
- Author(s)
  Md. Moksed Ali, Takami Takizawa, Kunio Kikuchi, Shigeru Saito, Toshihiro Takizawa
- Organizer
  IFPA 2012 Hiroshima Meeting
- Place of Presentation
  広島県広島市
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 絨毛外栄養膜における接着分子CD442012
- Author(s)
  高橋宏典,菊池邦生,大口昭英,薄井里英,桑田知之,松本久宣,佐藤幸保,藤原浩,松原茂樹,鈴木光明,瀧澤俊広
- Organizer
  浸潤能の検討第27回日本生殖免疫学会総会・学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 甲状腺微少浸潤型濾胞癌の術後遠隔転移を予測するためのバイオマーカーの開発:miR-221/222は有用な予測因子である2012
- Author(s)
  軸薗智雄,川本雅司,赤須東樹,廣川満良,菊池邦生,宮内昭,土屋眞一,瀧澤俊広,清水一雄
- Organizer
  第24回日本内分泌外科学会総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] CD44 accelerates trophobalstic invasion: in vitro invasion analysis using HTR8/SVneo cells2012
- Author(s)
  Hironori Takahashi, Kunio Kikuchi, Tomoyuki Kuwata, Rie Usui, Akihide Ohkuchi, Hisanori Matsumoto, Yukiyasu Sato, Hiroshi Fujiwara, Kumiko Ui-Tei, Shigeki Matsubara, Mitsuaki Suzuki1, Toshihiro Takizawa
- Organizer
  IFPA 2012 Hiroshima Meeting
- Place of Presentation
  広島県広島市
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 胎盤由来エクソソームを介した胎盤-母体間コミュニケーション2011
- Author(s)
  菊池邦生,アリモハメド,羅善順,石橋宰,石川朋子,瀧澤敬美,倉品隆平,石川源,右田真,大口昭英,松原茂樹,竹下俊行,瀧澤俊広
- Organizer
  第19回日本胎盤学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] エクソソームmicroRNAを介した胎盤-リンパ球間コミュニケーション:培養細胞を用いたモデル解析2011
- Author(s)
  アリモハメド,菊池邦生,石橋宰,石川朋子,瀧澤敬美,竹下俊行,瀧澤俊広
- Organizer
  第26回日本生殖免疫学会総会・学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 肝内胆管癌で発現が抑制されているmiRNAの機能解析の試み2011
- Author(s)
  菊池邦生, 川東豊, 石川朋子, 三嶋拓也, 水口義昭, 石橋宰, 吉田寛, 内田英二, 瀧澤俊広
- Organizer
  第116回日本解剖学会総会・全国学術集会
- Place of Presentation
  神奈川
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] 栄養膜浸潤における接着分子CD44の役割:浸潤能解析2011
- Author(s)
  高橋宏典,菊池邦生,松原茂樹,鈴木光明,瀧澤俊広
- Organizer
  第19回日本胎盤学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2011-09-30
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 絨毛外栄養膜細胞に発現しているCD44の機能解析:HTR8/SVneoを用いた浸潤能の検討2011
- Author(s)
  菊池邦生
- Organizer
  第26回日本生殖免疫学会
- Place of Presentation
  ウィンク愛知(愛知県)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] Placenta specific-microRNAs in normal pregnancy and preeclampsia.2011
- Author(s)
  Toshihiro Takizawa, Md.Moksed Ali, Osamu Ishibashi, Kunio Kikuchi, Takuji Kosuge, Shigeki Matsubara, Toshiyuki Takeshita.
- Organizer
  8th European Congress on Reproductive Immunology
- Place of Presentation
  ミュンヘン(ドイツ)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 胎盤由来エクソソームを介した胎盤-母体間コミュニケーション2011
- Author(s)
  菊池邦生
- Organizer
  第19回日本胎盤学会学術集会
- Place of Presentation
  東京ステーションコンファレンス(東京都)(招待講演)
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 肝内胆管癌で発現が抑制されているmiRNAの機能解析の試み2011
- Author(s)
  菊池邦生
- Organizer
  第116回日本解剖学会
- Place of Presentation
  東京
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] 瀧澤俊広絨毛外栄養膜細胞に発現しているCD44の機能解析:HTR8/SVneoを用いた浸潤能の検討2011
- Author(s)
  高橋宏典,菊池邦生,松原茂樹,鈴木光明
- Organizer
  第26回日本生殖免疫学会総会・学術集会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] 胆管上皮細胞で発現するmiRNAのプロファイリングと機能解析の試み2010
- Author(s)
  菊池邦生, 川東豊, 石川朋子, 三嶋拓也, 水口義昭, 石橋宰, 吉田寛, 内田英二, 田尻孝, 瀧澤俊広
- Organizer
  第12回日本RNA学会年会
- Place of Presentation
  東京
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] 肝内胆管癌で発現が抑制されているmiRNAの同定と機能の解析2010
- Author(s)
  菊池邦生
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] 肝内胆管癌で発現が抑制されているmiRNAの同定と機能の解析2010
- Author(s)
  菊池邦生, 川東豊, 石川朋子, 三嶋拓也, 水口義昭, 石橋宰, 吉田寛, 内田英二, 瀧澤俊広
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] 胆管上皮細胞に発現しているmiRNAの機能解析2010
- Author(s)
  菊池邦生, 川東豊, 石川朋子, 三嶋拓也, 水口義昭, 石橋宰, 吉田寛, 内田英二, 田尻孝, 瀧澤俊広
- Organizer
  第115回日本解剖学会総会・全国学術集会
- Place of Presentation
  岩手
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] 胆管上皮細胞に発現するmiRNAの機能解析2010
- Author(s)
  菊池邦生
- Organizer
  第115回日本解剖学会総会・全国学術集会
- Place of Presentation
  盛岡
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21591784
[Presentation] MicroRNAによるGRB2の発現制御を介した肝内胆管癌の移動能制御機構の解析
- Author(s)
  菊池　邦生
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  サンポートホール高松・かがわ国際会議場（香川県）
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] Methylation profile of C19MC-miRNA CpG island in trophoblast cell lines.
- Author(s)
  Kunio Kikuchi
- Organizer
  第18回国際胎盤学会
- Place of Presentation
  広島国際会議場（広島県）
- Invited
- Data Source
  KAKENHI-PROJECT-22791553
[Presentation] microRNAの網羅的解析手法と生殖免疫学分野での応用
- Author(s)
  菊池　邦生
- Organizer
  第２7回生殖免疫学会総会・学術集会
- Place of Presentation
  大阪医科大学（大阪府）
- Invited
- Data Source
  KAKENHI-PROJECT-22791553

1. TAKESHITA Toshiyuki (60188175)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. ISHIKAWA Tomoko (70212850)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. TAKIZAWA Toshihiro (90271220)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. ISHIBASHI Osamu (70293214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. TOMIYAMA Ryoko (40409214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YOSHIDA Hiroshi (60246999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. OHKUCHI Akihide (10306136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. FUJIWARA Yoko (50293105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 羅善順 (60339439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 森美貴 (00277576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 原田明希摩 (70535426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIYASHITA Masao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. MAKINO Kouji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. AKAGI Ichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 相澤康則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KIKUCHI Kunio 菊池 邦生

Research Projects

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Elucidation of the roles of placental microRNAs in the pathogenesis of preeclampsia and identification of novel prognostic factors for preeclampsia

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IgG transport mechanism of Fc gamma RIIb-containing compartments across the placental barrier

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Expression and functional analysis of miRNAs in human placenta:molecular and cellar research of IUGRPrincipal Investigator

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Profiling and functional analyses of microRNAs in human intrahepatic cholangiocarcinoma

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Profiling and functional analysis of microRNAs in follicular granulosa cells and their clinical application

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[Book] 臨床婦人科産科2011

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[Journal Article] Placenta-specific miRNA (miR-512-3p) targets PPP3R1 encoding the calcineurin B regulatory subunit in BeWo cells2014

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[Journal Article] Relationship between altered expression levels of MIR21, MIR143, and MIR205 and clinicopathologic features of esophageal squamous cell carcinoma2011

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[Journal Article] SnoN/SKIL modulates proliferationthrough control of hsa-miR-720 transcription in esophageal cancer cells.2011

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[Journal Article] 絨毛細胞におけるマイクロRNA2011

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[Journal Article] Genes that Integrate multiple adipogenic signaling pathways in human mesenchymal stem cells2011

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[Journal Article] 絨毛と胎盤をめぐる新知見【絨毛研究最前線4】絨毛細胞におけるマイクロRNA2011

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[Presentation] 栄養膜細胞におけるC19MCプロモーター領域のメチル化解析2014

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[Presentation] 胎盤特異的miRNA，miR-512-3pはPPP3R1を標的としている2013

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[Presentation] MicroRNAを介した絨毛栄養膜細胞による絨毛外栄養膜細胞の浸潤制御2013

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KIKUCHI Kunio 菊池邦生