HAYASAKA Haruko 早坂晴子

Researcher Number	70379246
Other IDs	https://orcid.org/0000-0003-1694-9248
Affiliation (Current)	2024: 近畿大学, 理工学部, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2023: 近畿大学, 理工学部, 准教授 2012 – 2014: 大阪大学, 医学(系)研究科(研究院), 助教 2007 – 2013: 大阪大学, 医学系研究科, 助教 2011: 大阪大学, 医学系・研究科, 助教 2009: 大阪大学, 大学院・医学系研究科, 助教 2005 – 2006: 大阪大学, 医学系研究科, 助手
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / General anatomy (including histology/embryology) / General anatomy (including Histology/Embryology) / Complex systems Except Principal Investigator Biological Sciences / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 90:Biomedical engineering and related fields / Biological Sciences / Immunology / Complex systems
Keywords	Principal Investigator 転写因子 / リンパ節 / 血管内皮細胞 / 免疫組織 / 腫瘍組織 / 腫瘍血管 / 血管 / 免疫細胞 / 組織微小環境 / 癌微小環境 … More / リンフォトキシン / 遺伝子発現マウス / 血管形成 / 癌 / メラノーマ増殖 / 抗腫瘍免疫 / メラノーマ / 腫瘍形成 / 内皮細胞分化 / 分化 / リンパ球 / 細胞分化 / 癌転移 / 乳癌 / リンパ節転移 / 膜ラッフル / がん転移 / ケモカインシグナル / 細胞移動 / 細胞遊走 / GPCR / 接着分子 / 細胞運動 / ケモカイン … More Except Principal Investigator ケモカイン / リゾリン脂質 / リンパ球 / 血管内皮細胞 / 免疫学 / 吸収代謝 / 機能性 / 生体利用性 / フラボノイド / リンパ輸送 / 高圧力顕微鏡 / 小型魚類 / おたまじゃくし / 圧拮抗作用 / 麻酔薬 / 樹状細胞 / リンパ節 / ケモカイン受容体 / ストローマ細胞 / 細胞接着 / リンパ球ホーミング / ケミカルバイオロジ / ケミカル・バイオロジ / Ｘ線結晶構造解析 / ケミカルバイオロジー / 一分子計測学 / X線結晶構造解析 / 核磁気共鳴法 / 構造生物学 / 領域とりまとめ / MAdCAM-1 / 分化誘導 / ES細胞 / nepmucin / 遺伝子発現 / 細胞接着分子 / HEV / 免疫細胞動員 / 腫瘍血管 / 生体分子 / 接着分子 / 細胞外基質 / 転移 / バイオテクノロジー / 糖鎖 / 癌 Less

麻酔薬圧拮抗作用の実時間イメージング
- Principal Investigator
  
  西山雅祥
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kindai University
Transcriptional regulation of angiogenesis and tissue differentiation in microenvironmentPrincipal Investigator
- Principal Investigator
  
  早坂晴子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Kindai University
Lymphatic transport of dietary flavonoids: elucidation of its driving force and physiological roles
- Principal Investigator
  
  室田佳恵子
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Shimane University
Mechanism of tissue-specific differentiation of vascular endothelial cells by Dach1 expressionPrincipal Investigator
- Principal Investigator
  
  Hayasaka Haruko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Kindai University
The mechanism underlying tumor inhibition by angiogenesis and immune cell recruitmentPrincipal Investigator
- Principal Investigator
  
  HAYASAKA HARUKO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Kindai University
Analysis of the transcription factor crosstalk in high endothelial venule formationPrincipal Investigator
- Principal Investigator
  
  HAYASAKA Haruko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Kinki University
  Osaka University
Characteristics and functions of stromal cells in secondary lymphoid tissues
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Understanding of the mechanism underlying the tissue-specific differentiation of high endothelial venule endothelial cellsPrincipal Investigator
- Principal Investigator
  
  HAYASAKA Haruko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka University
Integrative understanding of biological processes mediated by transient macromolecul ar complexes; New technology for visualizing physiologically metastable states
- Principal Investigator
  
  SHIMADA Ichio
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Analysis of the conformational transitions and functional modifications in membrane proteinsPrincipal Investigator
- Principal Investigator
  
  HAYASAKA Haruko
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka University
Elucidation of the mechanism underlying immune cell trafficking dependent on lysophospholipid signaling
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
腫瘍血管へ免疫細胞動員活性を誘導する生体プログラムの賦活化と抗腫瘍免疫監視の強化
- Principal Investigator
  
  田中稔之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hyogo University of Health Sciences
  Osaka University
Stromal factors regulating tumor cell motility
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University

[Book] Encyclopedia of Immunobiology2016
- Author(s)
  Miyasaka M, Hata E, Tohya K, Hayasaka H.
- Total Pages
  3126
- Publisher
  Elsevier
- Data Source
  KAKENHI-PLANNED-24111005
[Book] 癌研究と分子標的治療2011
- Author(s)
  早坂晴子(共著)
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-21121007
[Book] 癌研究と分子標的治療2011
- Author(s)
  早坂晴子
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] CXCL12 promotes CCR7 ligand?mediated breast cancer cell invasion and migration toward lymphatic vessels2022
- Author(s)
  Hayasaka Haruko、Yoshida Junichi、Kuroda Yasutaka、Nishiguchi Akihiro、Matsusaki Michiya、Kishimoto Kei、Nishimura Hitoshi、Okada Mari、Shimomura Yuki、Kobayashi Daichi、Shimazu Yoshihito、Taya Yuji、Akashi Mitsuru、Miyasaka Masayuki
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 4 Pages: 1338-1351
- DOI
  10.1111/cas.15293
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07278
[Journal Article] Dach1 transcription factor regulates the expression of peripheral node addressin and lymphocyte trafficking in lymph nodes.2022
- Author(s)
  Shintani A, Fukai S, Nobusawa R, Taniguchi K, Hatatani T, Nagai H, Sakai T, Yoshimura T, Miyasaka M. *Hayasaka H.
- Journal Title
  
  Current Research in Immunology
  
  Volume: 3 Pages: 175-185
- DOI
  10.1016/j.crimmu.2022.08.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06823, KAKENHI-PROJECT-19K07278
[Journal Article] Extracellular ATP Limits Homeostatic T Cell Migration Within Lymph Nodes2021
- Author(s)
  Kobayashi Daichi、Sugiura Yuki、Umemoto Eiji、Takeda Akira、Ueta Hisashi、Hayasaka Haruko、Matsuzaki Shinsuke、Katakai Tomoya、Suematsu Makoto、Hamachi Itaru、Yegutkin Gennady G.、Salmi Marko、Jalkanen Sirpa、Miyasaka Masayuki
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 786595-786595
- DOI
  10.3389/fimmu.2021.786595
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-21H02653, KAKENHI-PROJECT-19K07278, KAKENHI-PROJECT-19K22528
[Journal Article] CXCL12-stimulated lymphocytes produce secondary stimulants that affect the surrounding cell chemotaxis2021
- Author(s)
  Kurowarabe Kaoru、Endo Masataka、Kobayashi Daichi、Hayasaka Haruko
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 28 Pages: 101128-101128
- DOI
  10.1016/j.bbrep.2021.101128
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07278
[Journal Article] Endogenous Membrane Receptor Labeling by Reactive Cytokines and Growth Factors to Chase Their Dynamics in Live Cells2018
- Author(s)
  Takaoka Yousuke、Uchinomiya Shohei、Kobayashi Daichi、Endo Masataka、Hayashi Takahiro、Fukuyama Yoshiaki、Hayasaka Haruko、Miyasaka Masayuki、Ueda Takumi、Shimada Ichio、Hamachi Itaru
- Journal Title
  
  Chem
  
  Volume: 4 Issue: 6 Pages: 1451-1464
- DOI
  10.1016/j.chempr.2018.03.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08481, KAKENHI-PLANNED-17H06348, KAKENHI-PUBLICLY-18H04540, KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097
[Journal Article] Regulation of CCR7-dependent cell migration through CCR7 homodimer formation2017
- Author(s)
  Kobayashi D, Endo M, Ochi H, Hojo H, Miyasaka M, Hayasaka H
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1038-1038
- DOI
  10.1038/s41598-017-09113-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08481, KAKENHI-PROJECT-16H04180
[Journal Article] Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes.2016
- Author(s)
  Hata E, Sasaki N, Takeda A, Tohya K, Umemoto E, Akahoshi N, Ishii S, Bando K, Abe T, Kano K, Aoki J, Hayasaka H, Miyasaka M
- Journal Title
  
  Int Immunol.
  
  Volume: なし Issue: 6 Pages: 283-292
- DOI
  10.1093/intimm/dxv072
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-25460268, KAKENHI-PROJECT-16H05136
[Journal Article] Divergence of vascular specification in visceral lymphoid organs - genetic determinants and differentiation checkpoints.2016
- Author(s)
  Kellermayer Z, Hayasaka H, Kajtar B, Simon D, Robles EF, Martinez-Climent JA, Balogh P.
- Journal Title
  
  Int Rev Immunol.
  
  Volume: In press Issue: 6 Pages: 489-502
- DOI
  10.3109/08830185.2015.1059427
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-25460268
[Journal Article] Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility.2016
- Author(s)
  Takeda A, Kobayashi D, Aoi K, Sasaki N, Sugiura Y, Igarashi H, Tohya K, Inoue A, Hata E, Akahoshi N, Hayasaka H, Kikuta J, Scandella E, Ludewig B, Ishii S, Aoki J, Suematsu M, Ishii M, Takeda K, Jalkanen S, Miyasaka M, Umemoto E.
- Journal Title
  
  Elife
  
  Volume: 5
- DOI
  10.7554/elife.10561
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460960, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-25460268
[Journal Article] The HIV-1 gp120/CXCR4 axis promotes CCR7 ligand-dependent CD4 T cell migration: CCR7 homo- and CCR7/CXCR4 hetero-oligomer formation as a possible mechanism for up-regulation of functional CCR7.2015
- Author(s)
  Hayasaka H, Kobayashi D, Yoshimura H, Nakayama EE, Shioda T, Miyasaka M.
- Journal Title
  
  PLoS ONE.
  
  Volume: 10 Issue: 2 Pages: 1371-1371
- DOI
  10.1371/journal.pone.0117454
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-25460268, KAKENHI-PROJECT-25670218, KAKENHI-PROJECT-26670226, KAKENHI-PLANNED-24111005
[Journal Article] Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis2013
- Author(s)
  Bai Z
- Journal Title
  
  J. Immunology
  
  Volume: 190 Issue: 5 Pages: 2036-2048
- DOI
  10.4049/jimmunol.1202025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191, KAKENHI-PROJECT-22590440, KAKENHI-PROJECT-23790071, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24590252, KAKENHI-PLANNED-21121007, KAKENHI-ORGANIZER-22116001
[Journal Article] ケモカイン受容体の協働作用による効率的なリンパ球移動の誘導2013
- Author(s)
  小林　大地, 宮坂　昌之, 早坂　晴子
- Journal Title
  
  生体の科学
  
  Volume: 64 Pages: 398-399
- Data Source
  KAKENHI-PROJECT-25460268
[Journal Article] Dynamic changes in endothelial cell adhesion molecule nepmucin/CD300LG expression under physiological and pathological conditions2013
- Author(s)
  Umemoto, E., Takeda, A., Jin, S., Luo, Z., Nakahogi, N., Hayasaka, H., Lee, CM., Tanaka, T., and Miyasaka, M
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] Dynamic changes in endothelial cell adhesion molecule nepmucin/CD300LG expression under physiological and pathological conditions.2013
- Author(s)
  Umemoto, E, Takeda, A., Jin, S., Luo, Z., Nakahogi, N., Hayasaka, H., Lee, C.M., Tanaka, T. & Miyasaka, M.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 12 Pages: 1-12
- DOI
  10.1371/journal.pone.0083681
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121007, KAKENHI-PROJECT-23659671, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24590252, KAKENHI-PROJECT-25460268, KAKENHI-PROJECT-25460603
[Journal Article] FAK-related nonkinase is a multifunctional negative regulator of pulmonary fibrosis2013
- Author(s)
  Ding, Q., Cai, G-Q., Hu, M., Yang, Y., Zheng, A., Tang, Q., Gladson, CL., Hayasaka, H.,Wu, H., You, Z., Southern, BD., Grove, LM., Rahaman, SO., Fang,H., and Olman, MA
- Journal Title
  
  Am. J. Pathol
  
  Volume: 182 Pages: 1572-1584
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis2013
- Author(s)
  Bai, Z., Cai, L., Umemoto, E., Takeda, A., Tohya, K., Komai, Y., Veeraveedu, PT., Hata, E., Sugiura, Y., Kubo, A., Suematsu, M., Hayasaka, H., Okudaira, S., Aoki, J., Tanaka T., Albers, HMHG., Ovaa, H., and Miyasaka, M
- Journal Title
  
  J. Immunol
  
  Volume: 190 Pages: 2036-2048
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis.2013
- Author(s)
  Bai Z, Cai L, Umemoto E, Takeda A, Tohya K, Komai Y, Veeraveedu PT, Hata E, Sugiura Y, Kubo A, Suematsu M, Hayasaka H, Okudaira S, Aoki J, Tanaka T,Albers HM, Ovaa H, Miyasaka M.
- Journal Title
  
  J. Immunol
  
  Volume: 190 Pages: 2036-2048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] Constitutive plasmacytoid dendritic cell migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling2012
- Author(s)
  Umemoto, E., Otani, K Ikeno, T., Verjan Garcia N, Hayasaka, H., Bai, Z., Jang MH., Tanaka T., Ueda, K., and Miyasaka, M
- Journal Title
  
  J. Immunol
  
  Volume: 189 Pages: 191-199
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] Constitutive plasmacytoid dendritic cell migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling2012
- Author(s)
  Umemoto E., Otani, K Ikeno, T., Verjan Garcia N, Hayasaka H., Bai, Z., Jang MH., Tanaka T., Ueda, K., Miyasaka, M
- Journal Title
  
  J. Immunol
  
  Volume: 189 Pages: 191-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] Novel regulators of lymphocyte trafficking across high endothelial venules2011
- Author(s)
  Umemoto E, Hayasaka H Bai Z, Cai L.Yonekura S, Peng X, Takeda A, Tohya K, Miyasaka M
- Journal Title
  
  Crit.Rev.Immunol
  
  Volume: 31 Pages: 147-169
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] がんとリンフォイドケモカイン2011
- Author(s)
  黒田康嵩、宮坂昌之、早坂晴子、
- Journal Title
  
  侵襲と免疫
  
  Volume: 20 Pages: 38-39
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] Novel regulators of lymphocyte trafficking across high endothelial venules2011
- Author(s)
  Umemoto, E., Hayasaka, H., Bai, Z., Cai, L., Yonekura, S., Peng, X., Takeda, A., Tohya, K., Miyasaka, M
- Journal Title
  
  Crit. Rev. Immunol
  
  Volume: 31 Pages: 147-169
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] リンパ球トラフィキングをつかさどる新しい分子機構- 生理活性脂質産生酵素オートタキシンとその産物リゾホスファチジン酸の役割2011
- Author(s)
  Bai, Z., Cai, L., Umemoto E., Takeda A., Ikeno, T., Hata E., Hayasaka, H., Miyasaka, M.
- Journal Title
  
  炎症と免疫別冊
  
  Volume: 19 Pages: 8-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] ケモカインによる白血球、癌細胞の生体内移動調節とケモカイン共働作用の関与2011
- Author(s)
  早坂晴子、岡田麻里、白忠彬、黒田康嵩、吉田淳一、宮坂昌之
- Journal Title
  
  生化学
  
  Volume: 83 Pages: 930-937
- NAID
  10029850204
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] 癌の進展、転移に関与するリンフォイドケモカイン2011
- Author(s)
  早坂晴子、宮坂昌之
- Journal Title
  
  実験医学増刊
  
  Volume: 29 Pages: 119-124
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] リンパ球トラフィキングをつかさどる新しい分子機構-生理活性脂質産生酵素オートタキシンとその産物リゾフォスファチジン酸の役割2011
- Author(s)
  白忠彬、蔡林君、梅本英司、池野嵩、秦枝里奈、早坂晴子、宮坂昌之
- Journal Title
  
  炎症と免疫別冊
  
  Volume: 19 Pages: 8-13
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] 癌の進展、転移に関与するリンフォイドケモカイン2011
- Author(s)
  早坂晴子、宮坂昌之
- Journal Title
  
  実験医学増刊
  
  Volume: 29 Pages: 119-124
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] ケモカインによる白血球、癌細胞の生体内移動調節とケモカイン共働作用の関与2011
- Author(s)
  早坂晴子、岡田麻里、白忠彬、黒田康嵩、吉田淳一、宮坂昌
- Journal Title
  
  生化学
  
  Volume: 83 Pages: 930-937
- NAID
  10029850204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] リンパ球トラフィキングをつかさどる新しい分子機構-生理活性脂質産生酵素オートタキシンとその産物リゾフォスファチジン酸の役割2011
- Author(s)
  白忠彬、蔡林君、梅本英司、池野嵩、秦枝里奈、早坂晴子、宮坂昌之
- Journal Title
  
  炎症と免疫別冊
  
  Volume: 19 Pages: 8-13
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] Novel regulators of lymphocyte trafficking across high endothelial venules2011
- Author(s)
  Umemoto, E., Hayasaka, H., Bai, Z., Cai, L., Yonekura, S., Peng, X., Takeda, A., Tohya, K., and Miyasaka, M
- Journal Title
  
  Crit. Rev .Immunol.
  
  Volume: 31 Pages: 147-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] 癌の進展、転移に関与するリンフォイドケモカイン2011
- Author(s)
  早坂晴子、宮坂昌之
- Journal Title
  
  実験医学[増刊]
  
  Volume: 29 Pages: 119-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] Novel regulators of lymphocyte trafficking across high endothelial venules2011
- Author(s)
  Umemoto, E., Hayasaka, H., Bai, Z., Cai, L., Yonekura, S., Peng, X., Takeda, A., Tohya, K. & Miyasaka, M.
- Journal Title
  
  Crit. Rev. Immunol.(Review)
  
  Volume: 312 Pages: 147-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390151
[Journal Article] ケモカインによる白血球,癌細胞の生体内移動調節とケモカイン共働作用の関与2011
- Author(s)
  早坂晴子,岡田麻里,白忠彬,黒田康嵩,吉田淳一,宮坂昌之
- Journal Title
  
  生化学
  
  Volume: 83(10) Pages: 920-929
- NAID
  10029850204
- URL
  http://www.jbsoc.or.jp/seika/wp-content/uploads/2013/05/83-10-06.pdf
- Data Source
  KAKENHI-ORGANIZER-21121001
[Journal Article] Novel regulators of lymphocyte trafficking across high endothelial venules2011
- Author(s)
  Umemoto, E., Hayasaka, H., Bai, Z., Cai, L., Yonekura, S., Peng, X., Takeda, A., Tohya, K., Miyasaka, M.
- Journal Title
  
  Crit.Rev.Immunol.
  
  Volume: 31(Review) Pages: 147-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390151
[Journal Article] がんとリンフォイドケモカイン2011
- Author(s)
  黒田康嵩、宮坂昌之、早坂晴子
- Journal Title
  
  侵襲と免疫
  
  Volume: 20 Pages: 38-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] Novel regulators of lymphocyte trafficking across high endothelial venules2011
- Author(s)
  Umemoto E, Hayasaka H Bai Z, Cai L.Yonekura S, Peng X, Takeda A, Tohya K, Miyasaka M
- Journal Title
  
  Crit.Rev.Immunol
  
  Volume: 31 Pages: 147-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] Neogenesis and development of the high endothelial venules that mediate lymphocyte trafficking2010
- Author(s)
  Hayasaka H
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 2302-2308
- NAID
  10027833068
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] Neogenesis and development of the high endothelial venules that mediate lymphocyte trafficking.2010
- Author(s)
  Hayasaka, H., Taniguchi, K., Fukai, S., Miyasaka, M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Pages: 2302-2308
- NAID
  10027833068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390151
[Journal Article] Neogenesis and development of the high endothelial venules that mediate lymphocyte trafficking2010
- Author(s)
  Hayasaka H
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 2302-2308
- NAID
  10027833068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] Two-state conformations in the hyaluronan-binding domain regulate CD44 adhesiveness under flow condition.2010
- Author(s)
  Ogino, S., Nishida, N., Umemoto, R., Suzuki, M., Takeda, M., Terasawa, H., Kitayama, J., Matsumoto, M., Hayasaka, H., Miyasaka, M., Ichio, S.
- Journal Title
  
  Structure
  
  Volume: 18 Pages: 649-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390151
[Journal Article] Neogenesis and development of the high endothelial venules that mediate lymphocyte trafficking2010
- Author(s)
  Hayasaka, H., Taniguchi, K., Fukai, S. & Miyasaka, M.
- Journal Title
  
  Cancer Sci.(Review)
  
  Volume: 101 Pages: 2302-2308
- NAID
  10027833068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390151
[Journal Article] Two-state conformations in the hyaluronan-binding domain regulate CD44 adhesiveness under flow condition2010
- Author(s)
  Ogino, S., Nishida, N., Umemoto, R., Suzuki, M., Takeda, M., Terasawa, H., Kitayama, J., Matsumoto, M., Hayasaka, H., Miyasaka, M., and Shimada, I
- Journal Title
  
  Structure
  
  Volume: 18 Pages: 649-656
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] Neogenesis and development of the high endothelial venules that mediate lymphocyte trafficking2010
- Author(s)
  Hayasaka, H., Taniguchi, K., Fukai, S. & Miyasaka, M
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Pages: 2302-2308
- NAID
  10027833068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] Neogenesis and development of the high endothelial venules that mediate lymphocyte trafficking2010
- Author(s)
  Hayasaka, H., Taniguchi, K., Fukai, S. and Miyasaka, M
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 2302-2308
- NAID
  10027833068
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] Two-state conformational equilibrium of the hyaluronan-binding domain regulates adhesiveness of CD44 under flow condition2010
- Author(s)
  Shinji Ogino, Noritaka Nishida, Ryo Umemoto, Miho Suzuki, Mitsuhiro Takeda, Hiroaki Terasawa, Joji Kitayama, Masanori Matsumoto, Haruko Hayasaka, Masayuki Miyasaka, Ichio Shimada
- Journal Title
  
  Structure
  
  Volume: 18 Pages: 649-656
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21121001
[Journal Article] Two-state conformations in the hyaluronan-binding domain regulate CD44 adhesiveness under flow condition2010
- Author(s)
  Ogino, S., Nishida, N., Umemoto, R., Suzuki, M., Takeda, M., Terasawa, H., Kitayama, J., Matsumoto, M., Hayasaka, H., Miyasaka, M., and Shimada, I
- Journal Title
  
  Structure
  
  Volume: 18 Pages: 649-656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590191
[Journal Article] CXCL12 promotes CCR7-dependent naïve T cell trafficking to lymph nodes and Peyer's patches2009
- Author(s)
  Bai, Z, Hayasaka, H (co-first authors), Kobayashi, M, Li,W, Guo, Z, Jang, MH, Kondo, A, Choi, BI, Iwakura, Y, and Miyasaka, M
- Journal Title
  
  J. Immunol
  
  Volume: 182 Pages: 1287-1295
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] CXCL12 promotes CCR7-dependent naive T cell trafficking to lymphnodes and Peyer's patches.2009
- Author(s)
  Bai Zhongbin, Haruko Hayasaka, et.al
- Journal Title
  
  Journal of Immunology VOL.182
  
  Pages: 1287-1295
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121007
[Journal Article] CXCL12 promotes CCR7-dependent naive T-cell trafficking to lymphnodes and Peyer's patches.2009
- Author(s)
  ^*Bai, Z., ^*Hayasaka, H (^*equal contribution)
- Journal Title
  
  J.Immunol. 182
  
  Pages: 1287-1295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] CXCL 12 promotes CCR7-dependent nalve T-cell trafficking to lymph nodes and Peyer's patches.2009
- Author(s)
  *Bai, Z., *Hayasaka, H(*equal contribution)
- Journal Title
  
  J.Immunol. 182
  
  Pages: 1287-1295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390151
[Journal Article] (equal contribution): CXC chemokine ligand 12 promotes CCR7-dependent naive T-cell trafficking to lymph nodes and Peyer' s patches2009
- Author(s)
  Bai, Z., * Hayasaka, H., Kobayashi, M., Li, W., Guo, Z., Jang, M. H., Kondo, A., Choi, B., Iwakura, Y. & Miyasaka, M
- Journal Title
  
  J. Immunol.
  
  Volume: 182 Pages: 1287-1295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390151
[Journal Article] CXCL12 promotes CCR7-dependent naive T-cell trafficking to lymph nodes and Peyer's patches.2009
- Author(s)
  *Bai, Z., *Hayasaka, H., Kobayashi, M., Li, W., Guo, Z., Jang, M.H., Kondo, A., Choi, B., Iwakura, Y., Miyasaka, M. (*equal contribution)
- Journal Title
  
  J. Immunol. 182
  
  Pages: 1287-1295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] CXCL12 promotes CCR7-dependent naive T-cell trafficking to lymph nodes and Peyer's patches2009
- Author(s)
  Bai, Z., Hayasaka, H.(equal contribution)
- Journal Title
  
  J. Immunol 182
  
  Pages: 1287-1295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Involvement of a lysophosphatidic-acid generating enzyme autotaxin in lymphocyte-endothelial cell interactions.2008
- Author(s)
  *Nakasaki, T., *Tanaka, T., Okudaira, S., Hirosawa, M., Umemoto, E., Otani, K., Jin, S., Bai, Z., Hayasaka, H., Fukui, Y., Aozasa, K., Fujita, N., Tsuruo, T., Ozono, K., Aoki, J., Miyasaka, M. (*equal contribution)
- Journal Title
  
  Am. J. Pathol. 173
  
  Pages: 1566-1576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Binding of lymphoid chemokines to collagen IV that accumulates in the basal lamina of high endothelial venules; its implication in lymphocyte trafficking.2007
- Author(s)
  Yang, B. -G., Tanaka, T., Jang, M.H., Bai, Z., Hayasaka, H., Miyasaka, M.
- Journal Title
  
  J. Immunol. 179
  
  Pages: 4376-4382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Plasmacytoid dendritic cells employ multiple cell adhesion molecules sequentially to interact with high endothelial venule cells - Molecular basis of their trafficking to lymph nodes.2007
- Author(s)
  *Matsutani, T., *Tanaka, T., Tohya, K., Otani, K., Jang, M.H., Umemoto, E., Taniguchi, K., Hayasaka, H., Ueda, K., Miyasaka, M. (*equal contribution)
- Journal Title
  
  Int. Immunol. 19
  
  Pages: 1031-1037
- NAID
  10020107880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragments.2006
- Author(s)
  Sugahara, K.N., Hirata, T., Hayasaka, H., Stern, R., Murai, T., Miyasaka, M.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 5861-5868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] CXCL13 is an arrest chemokine for B cells in high endothelial venules.2005
- Author(s)
  *Kanemitsu, N., *Ebisuno, Y., *Tanaka, T., Otani, K., Hayasaka, H., Kaisho, T., Akira, S., Katagiri, K., Kinashi, T., Fujita, N., Tsuruo, T., Miyasaka, M. (*equal contribution)
- Journal Title
  
  Blood 106
  
  Pages: 2613-2618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] Chemokines in tumor progression and metastasis.2005
- Author(s)
  Tanaka, T., Bai, Z., Srinoulprasert, Y., Yang, B. -G., Hayasaka, H., Miyasaka, M.: Review
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 317-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014056
[Journal Article] ケモカイン受容体の協働作用により効率的なリンパ球移動が誘導される
- Author(s)
  小林大地、宮坂昌之、早坂晴子. 生体の科学
- Journal Title
  
  生体の科学
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] 転写因子 Dach1 による腫瘍内血管形成および腫瘍形成への影響2022
- Author(s)
  畑谷友宥、藤岡葵、松本りぼん、藤澤晃、向井めぐみ、早坂晴子
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-22K06823
[Presentation] Transcription factor Dach1 regulates gene expression pattern in the endothelial cells of lymph node high endothelial venules2022
- Author(s)
  信澤怜佳、永井隼斗、新谷ありさ、深井祥子、早坂晴子
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] 転写因子 Dach1 が腫瘍流入領域リンパ節血管形成に与える影響2021
- Author(s)
  信澤怜佳、永井隼斗、畑谷友宥、新谷ありさ、深井祥子、早坂晴子
- Organizer
  がん転移学会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] Establishment of the luciferase complementation assay to detect CCR7 homodimerization2021
- Author(s)
  Hitoshi Nishimura, Kei Kishimoto, Kurowarabe Kaoru, Haruko Hayasaka
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] An enhanced anti-melanoma immune response in the Ccl21a-deficient mice2021
- Author(s)
  Ryota Hayashi, Hinami Kawahata, Kakeru Fujiwara, Kaoru Kurowarabe, Yuki Yamada, Izumi Ohigashi, Haruko Hayasaka
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] The roles of endogenous and tumor-derived CCL21-Ser in melanoma growth2021
- Author(s)
  Megumi Miyamoto, Kaoru Kurowarabe,Kakeru Fujiwara, Sachie Ota, Izumi Ohigashi, Haruko Hayasaka
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] The role of transcription factor Dach1 in high endothelial venule development in mouse lymph nodes2021
- Author(s)
  Arisa Shintani, Hayato Nagai, Reika Nobusawa, Shoko Fukai, Haruko Hayasaka
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] 転写因子 Dach1 による腫瘍内血管形成の促進2021
- Author(s)
  畑谷友宥、向井めぐみ、田辺薫佳、曽根麻由奈、早坂晴子
- Organizer
  がん転移学会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] リンパ節高内皮細静脈血管形成における転写因子 Dach1 遺伝子の関与2020
- Author(s)
  新谷ありさ、永井隼人、信澤怜佳、片貝璃子、深井祥子、早坂晴子
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] リンパ節血管形成における転写因子Dach1遺伝子の関与2019
- Author(s)
  永井隼斗、新谷ありさ、酒井智弘、深井祥子、早坂晴子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] リンパ球感の細胞遊走を制御する走化性因子の探索2019
- Author(s)
  黒蕨　馨、遠藤　正隆、早坂　晴子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] リンパ球感の細胞遊走を制御する走化性因子の探索2019
- Author(s)
  黒蕨　馨、遠藤　正隆、早坂　晴子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] リンパ節血管形成における転写因子Dach1遺伝子の関与2019
- Author(s)
  永井隼斗、新谷ありさ、酒井智弘、深井祥子、早坂晴子
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] ヒト乳がん細胞リンパ節転移におけるCCR7およびCXCR4リガンドケモカインの関与2019
- Author(s)
  早坂　晴子、松田　幸、宮坂　昌之
- Organizer
  第28回　日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07278
[Presentation] ヒト乳がん細胞リンパ節転移におけるCCR7およびCXCR4リガンドケモカインの関与2019
- Author(s)
  早坂　晴子、松田　幸、宮坂　昌之
- Organizer
  第28回　日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] 免疫細胞、がん細胞の組織移動におけるケモカインの関与2019
- Author(s)
  早坂　晴子
- Organizer
  第5回　幹細胞・細胞分化に関する合同リトリート
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] Ccl21a KO マウスにおけるB16F10メラノーマ増殖能の低下2018
- Author(s)
  藤原翔, 鈴木崚介, 大東いずみ, 高浜洋介, 早坂晴子
- Organizer
  日本がん転移学会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] Dach1恒常的発現マウスを用いた高内皮細静脈形成メカニズムの解析2018
- Author(s)
  早坂晴子、永井隼斗、酒井智弘、曽根麻由奈、野出裕介
- Organizer
  日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] ケモカイン刺激で誘導されるリンパ球遊走性物質の産生2018
- Author(s)
  遠藤正隆、黒蕨馨、小林大地、池本光志、早坂晴子
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] リンパ節高内皮細静脈内皮細胞分化におけるDach1遺伝子の機能解析2018
- Author(s)
  野出裕介, 奥田　結衣, 永井隼人, 酒井　智弘, 深井　祥子, 早坂晴子
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] ケモカイン依存的細胞遊走におけるケモカイン受容体の局在変化と脂質ラフトの役割2017
- Author(s)
  遠藤正隆, 小林　大地、高岡洋輔、早坂晴子
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] CCR7 homo-dimerization regulates CCR7 ligand-dependent cell migration and signaling2017
- Author(s)
  Haruko Hayasaka, Daichi Kobayashi, Masataka Endo, Hironobu Hojo, Masayuki Miyasaka
- Organizer
  北米細胞生物学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] メラノーマ組織に形成される高内皮細静脈様血管の検出2017
- Author(s)
  藤原　翔、森　空悟、大東　いずみ、高浜　洋介、早坂　晴子
- Organizer
  日本癌転移学会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] 血管特異的 Dach1 ノックアウトマウスを用いた高内皮細静脈形成メカニズムの解析2017
- Author(s)
  酒井智弘、長江崚平、松本　萌、平野　晴香、早坂晴子
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] CCR7 homo-oligomerization plays an important role in CCR7-dependent signaling.2016
- Author(s)
  Kobayashi D, Miyasaka M, Hayasaka H.
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県）
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-16K08481
[Presentation] CCR7 homo-oligomerization plays an important role in CCR7-dependent signaling.2016
- Author(s)
  Kobayashi D, Miyasaka M, Hayasaka H.
- Organizer
  The 45th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Okinawa Convention Center (Ginowan, Okinawa)
- Year and Date
  2016-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24111005
[Presentation] The role of the transcription factor Dach1 in the high endothelial venule development2015
- Author(s)
  Haruko Hayasaka, Peter Balogh, Masayuki Miyasaka,
- Organizer
  日本免疫学会
- Place of Presentation
  札幌コンベンションセンター (北海道）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25460268
[Presentation] CCR7 ホモ多量体形成による細胞遊走調節機構2015
- Author(s)
  小林大地、宮坂昌之、早坂晴子
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸国際会議場 (兵庫県）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25460268
[Presentation] The role of the transcription factor Dach1 in the high endothelial venule development.2015
- Author(s)
  Hayasaka H, Balogh P, Miyasaka M.
- Organizer
  The 44th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Sapporo Convention Center (Sapporo, Hokkaido)
- Year and Date
  2015-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24111005
[Presentation] CCR7 homo-oligomerization regulates CCR7 ligand dependent cell migration.2015
- Author(s)
  Kobayashi D, Ochi H, Muroka K, Miyasaka M, Hayasaka H.
- Organizer
  The 38th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Kobe Portopia Hotel, etc (Kobe, Hyogo)
- Year and Date
  2015-12-01
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24111005
[Presentation] 癌リンパ節転移研究における毛細リンパ管モデルの利用2014
- Author(s)
  早坂　晴子　宮坂　昌之
- Organizer
  三次元生体組織構築シンポジウム
- Place of Presentation
  大阪大学中之島センター
- Year and Date
  2014-12-09
- Invited
- Data Source
  KAKENHI-PROJECT-25460268
[Presentation] Chemokine receptor oligomerization : a potential mechanism for regulating lymphocyte and cancer cell migration2013
- Author(s)
  Haruko Hayasaka, Daichi Kobayashi, Masayuki Miyasaka
- Organizer
  第51回日本生物物理学会シンポジウム
- Place of Presentation
  京都国際会議場
- Year and Date
  2013-10-29
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] The role of LPA receptors on endothelial cells in lymphocyte trafficking across high endothelial venules of lymph nodes.2013
- Author(s)
  Hata, E., Sasaki, N., Takeda, A., Umemoto, E., Hayasaka, H. & Miyasaka, M.
- Organizer
  The 42nd Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PLANNED-24111005
[Presentation] ケモカイン受容体多量体形成による細胞動態の調節2013
- Author(s)
  早坂晴子,小林大地,宮坂昌之
- Organizer
  第51回日本生物物理学会年会ワークショップ「過渡的複合体が関わる生命現象の統合的理解」
- Place of Presentation
  京都府京都市
- Year and Date
  2013-10-29
- Data Source
  KAKENHI-ORGANIZER-21121001
[Presentation] The HIV-1 gp120/CXCR4 interaction promotes CCR7-dependent CD4 T cell trafficking into lymph nodes2012
- Author(s)
  Hayasaka H, Yoshimura H, Kobayashi D, Nakayama EE, Shioda T, Bai Z, Miyasaka M
- Organizer
  Keystone Symposia
- Place of Presentation
  (Poster発表)
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] 乳癌リンパ節転移におけるケモカイン受容体CXCRおよびCCR7の協働作用2012
- Author(s)
  早坂　晴子
- Organizer
  日本癌学会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] The HIV-1 gp 120/CXCR4 interaction promotes CCR7-dependent CD4 T cell trafficking into lymph nodes2012
- Author(s)
  Hayasaka H, Yoshimura H, Kobayashi D, Nakayama EE, Shioda T.Bai Z, Miyasaka M
- Organizer
  Keystone Symposium
- Place of Presentation
  Beaver Run Resort, Brickenridge, Colorado (USA)
- Year and Date
  2012-01-10
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] 乳癌リンパ節転移におけるケモカイン受容体CXCRおよびCCR7の協働作用2012
- Author(s)
  早坂　晴子
- Organizer
  日本癌学会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] The HIV-1 gp120/CXCR4 interaction promotes CCR7-dependent CD4 T cell trafficking into lymph nodes2012
- Author(s)
  Hayasaka H, Yoshimura H, Kobayashi D.Nakayama EE, Shioda T.Bai Z, Miyasaka M
- Organizer
  Keystone Symposium
- Place of Presentation
  Beaver Run Resort, Brick enridge, Colorado (USA)
- Year and Date
  2012-01-10
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] ケモカインレセプターの準安定状態と細胞動態2012
- Author(s)
  早坂晴子、吉村洋美、白忠彬、宮坂昌之
- Organizer
  蛋白質科学会
- Place of Presentation
  札幌
- Year and Date
  2012-06-16
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] 乳癌リンパ節転移におけるケモカイン受容体CXCR4およびCCR7の協働作用2012
- Author(s)
  早坂晴子、島津徳人、青葉孝昭、宮坂昌之
- Organizer
  日本癌学会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] he HIV-1 gp120/CXCR4 interaction promotes CCR7-dependent CD4 T cell trafficking into lymph nodes.2012
- Author(s)
  Hayasaka H., Yoshimura H., Kobayashi D., Nakayama E.E., Shioda T., Bai Z., Miyasaka M.
- Organizer
  The Keystone Symposia
- Place of Presentation
  Cololado, USA
- Year and Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] 白血球、癌細胞の生体内動態調節とケモカイン共働作用2011
- Author(s)
  早坂晴子
- Organizer
  新学術領域研究「過渡的複合体」公開シンポジウム
- Place of Presentation
  東京大学薬学部講堂(招待講演)
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] In vivo inhibition of the autotaxin/LPA axis results in inhibition of lymphocyte transmigration across high endothelial venules of lymph nodes2011
- Author(s)
  Hata, E., Bai, Z., Cai, L., Umemoto, E., Hayasaka, H., Miyasaka, M.
- Organizer
  The 40th annual meeting of the Japanese Society for Immunology
- Place of Presentation
  Chiba
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21390151
[Presentation] A transcription factor preferentially expressed in the high endothelial venule endothelial cells of the perinatal mouse lymph nodes2011
- Author(s)
  Haruko Hayasaka, Shoko Fukai, Masayuki Miyasaka
- Organizer
  日本免疫学会
- Place of Presentation
  幕張メッセ
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] Inhibition of the Autotaxin/LPA axis results in inhibition of lymphocyte release from the endothelial cells of high endothelial venules in vitro2011
- Author(s)
  Cai, L., Bai, Z., Umemoto, E., Hayasaka, H., Takeda, A., Miyasaka, M.
- Organizer
  The 40th annual meeting of the Japanese Society for Immunology
- Place of Presentation
  Chiba
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21390151
[Presentation] 白血球、癌細胞の生体内動態調節とケモカイン協働作用2011
- Author(s)
  早坂晴子
- Organizer
  新学術領域研究「過渡的複合体」公開シンポジウム
- Place of Presentation
  東京大学薬学部講堂
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] 白血球、癌細胞の生体内動態調節とケモカイン共働作用2011
- Author(s)
  早坂晴子
- Organizer
  新学術領域研究「過渡的複合体」公開シンポジウム
- Place of Presentation
  東京大学薬学部講堂(招待講演)
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] 白血球、癌細胞の生体内動態調節におけるケモカイン共働作用2011
- Author(s)
  早坂晴子
- Organizer
  新学術領域研究「過渡的複合体」公開シンポジウム
- Place of Presentation
  東京大学薬学部東京
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-ORGANIZER-21121001
[Presentation] The autotaxin/lysophosphatidic acid axis regulates lymphocyte extravasation at lymph node high endothelial venules2011
- Author(s)
  Bai, Z., Cai, L., Umemoto, E, Tohya, K., Takeda, A., Hata, E., Hayasaka, H., Tanaka, T., Miyasaka, M.
- Organizer
  Keystone Symposia Conference on Chemokines and Leukocyte Trafficking
- Place of Presentation
  Colorado, U.S.A.
- Year and Date
  2011-01-09
- Data Source
  KAKENHI-PROJECT-21390151
[Presentation] Autotoxin, a new regulator of lymphocyte trafficking across high endothelial venules2011
- Author(s)
  Miyasaka, M., Bai, Z., Cai, L., Hayasaka, H., Umemoto, E.
- Organizer
  JSICR-MMCB2011 joint meeting)
- Place of Presentation
  Osaka((Invited lecture)
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-21390151
[Presentation] The effects of HIV-1 gp120 on CCR7 ligand-induced human CD4 T cell migration2010
- Author(s)
  Hayasaka H., Yoshimura H., Nakayama E.E., Shioda T., Bai Z., Miyasaka M
- Organizer
  The 14thinternational congress of immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-02-10
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] The functional role of a lipid-generating enzyme, autotaxin, in lymphocyte trafficking across the venules of lymphoid tissues.2010
- Author(s)
  Miyasaka, M., Bai, Z., Linjun Cai, L., Hayasaka, H., Umemoto, E.
- Organizer
  2nd Synthetic Immunology Workshop
- Place of Presentation
  Kyoto(招待講演)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-21390151
[Presentation] ケモカインレセプターの準安定状態と細胞動態2010
- Author(s)
  早坂晴子、吉村洋美、白忠彬、宮坂昌之
- Organizer
  第10回日本蛋白質科学会年会企画ワークショップ
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] The role of an LPA-generating enzyme autotaxin in lymphocyte trafficking across the venules of lymphoid tissues.2010
- Author(s)
  Cai, L., Bai, Z., Umemoto, E., Hayasaka, H., Miyasaka, M.
- Organizer
  The 31st Meeting of the Japanese Society of Inflammation and Regeneration
- Place of Presentation
  Tokyo
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-21390151
[Presentation] The effects of HIV-1 gp120 on CCR7 ligand-induced human CD4 T cell trafficking2010
- Author(s)
  Hayasaka H, Yoshimura H, Nakayama EE, Shioda T, Bai Z, Miyasaka M
- Organizer
  第14回国際免疫学会
- Place of Presentation
  (口頭発表)
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] ケモカインレセプターの準安定状態と細胞動態2010
- Author(s)
  早坂晴子、吉村洋美、白忠彬、宮坂昌之
- Organizer
  第10回日本蛋白質科学会年会ワークショップ「過渡的複合体の視点から生命現象を捉えなおす」
- Place of Presentation
  北海道札幌市
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-ORGANIZER-21121001
[Presentation] Luminal expression of autotaxin and its role in lymphocyte trafficking across the venules of lymphoid tissues.2010
- Author(s)
  Bai, Z., Umemoto, E., Hayasaka, H., Cai, L., Aold, J., Okudaira, S., Jin, T., Ishii, M., Fujii, F., Watanabe, T., Miyasaka, M.
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-21390151
[Presentation] The effect of HIV-1 gp120 on CCR7 ligand-induced human CD4 T cell trafficking2010
- Author(s)
  Hayasaka H
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-22590191
[Presentation] The effect of HIV-1 gp 120 on CCR7 ligand-induced human CD4 T cell trafficking2010
- Author(s)
  Hayasaka H
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] 乳癌細胞におけるCXCL12とCCR7リガンド協働作用の解析.2009
- Author(s)
  早坂晴子, 他
- Organizer
  第18回日本がん転移学会学術集会・総会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-17014056
[Presentation] 乳癌細胞におけるCXCL12とCCR7リガンド協働作用の解析2009
- Author(s)
  早坂晴子
- Organizer
  第18回日本がん転移学会学術集会・総会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-17014056
[Presentation] HIV-1外被糖蛋白分子gp120によるCCR7リガンド誘導性ヒトCD4 T細胞ケモタキシスの促進作用2009
- Author(s)
  早坂晴子
- Organizer
  日本免疫学会
- Place of Presentation
  グランキューブ大阪(大阪府)
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] Searching for genes that control HEV endothelial cell differentiation2009
- Author(s)
  早坂晴子
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] 乳癌細胞におけるCXCL12とCCR7リガンド協働作用の解析2009
- Author(s)
  早坂晴子
- Organizer
  がん転移学会
- Place of Presentation
  旭川グランドホテル(北海道)
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] Synergy between CCR7 and CXCR4 signaling in T lymphocyte Migration ; HIV-1 gp120 facilitates CCL21-induced chernotaxis in T lymphocytes in a CXCR4-dependent manlier2008
- Author(s)
  Hayasaka, H.
- Organizer
  The 38th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-17014056
[Presentation] 癌細胞のケモタキシスにおけるケモカイン協働作用の解析2007
- Author(s)
  早坂晴子
- Organizer
  第16回日本がん転移学会学術集会
- Place of Presentation
  富山
- Year and Date
  2007-07-09
- Data Source
  KAKENHI-PROJECT-17014056
[Presentation] 癌細胞のケモタキシスにおけるケモカイン協働作用の解析.2007
- Author(s)
  早坂晴子, 他
- Organizer
  第16回日本がん転移学会学術集会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-17014056
[Presentation] Search for endothelial molecules that inhibit lymphocyte entry into tumor tissues2007
- Author(s)
  Hayasaka, H.
- Organizer
  The 66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17014056
[Presentation] ケモカイン受容体多量体形成による細胞動態の調節
- Author(s)
  早坂　晴子
- Organizer
  日本生物物理学会
- Place of Presentation
  京都国際会議場
- Invited
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] The role of LPA4/6 receptors in lymphocyte trafficking across high endothelial venules of lymph nodes.
- Author(s)
  Hata, E., Sasaki, N., Takeda, A., Umemoto, E., Hayasaka, H. & Miyasaka, M.
- Organizer
  The 43rd Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Kyoto
- Year and Date
  2014-12-10 – 2014-12-14
- Data Source
  KAKENHI-PLANNED-24111005
[Presentation] Functional analysis of the subcapsular sinus floor that allows leukocyte migration from the sinus to the lymph node parenchyma.
- Author(s)
  Sasaki, N., Hata, E., Umemoto, E., Hayasaka, H. & Miyasaka, M.
- Organizer
  The 43rd Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Kyoto
- Year and Date
  2014-12-10 – 2014-12-14
- Data Source
  KAKENHI-PLANNED-24111005
[Presentation] CXCR4 ligands promote CCR7-dependent CD4 T cell migration - possible involvement of CCR7 oligomerization
- Author(s)
  Haruko Hayasaka, Daichi Kobayashi, Masayuki Miyasaka
- Organizer
  日本免疫学会
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-25460268
[Presentation] CXCR4　ｌigands promote CCR7-dependent CD4 T cell migration- possible involvement of CCR7 oligomerization
- Author(s)
  早坂　晴子、小林　大地、宮坂　昌之
- Organizer
  日本免疫学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PLANNED-21121007
[Presentation] Chemokine receptor oligomerization: a potential mechanism for regulating lymphocyte and cancer cell migration
- Author(s)
  Haruko Hayasaka
- Organizer
  日本生物物理学会
- Place of Presentation
  Kyoto
- Invited
- Data Source
  KAKENHI-PROJECT-25460268

1. MIYASAKA Masayuki (50064613)

# of Collaborated Projects: 5 results

# of Collaborated Products: 52 results
2. UMEMOTO Eui (90452440)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. BAI Zhongbin (10512840)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
4. VERJAN-GARCIA Noel (90533216)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TANAKA Toshiyuki (30217054)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
6. HAMACHI Itaru (90202259)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SHIRAKAWA Masahiro (00202119)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MORIKAWA Kosuke (80012665)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. JANG Myoung-ho (70420453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. HIRATA Takako (00346199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SHIMADA Ichio (70196476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KOHDA Daisuke (80186618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FUNATSU Takashi (00190124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. AKUTSU Hideo (60029965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. INAGAKI Fuyuhiko (70011757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NISHIMURA Yoshifumi (70107390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. CAI Linjun (90584079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
18. 片貝智哉 (00324682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 西山雅祥 (10346075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 室田佳恵子 (40294681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 高橋信之 (50370135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中村俊之 (90706988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Takeda Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
24. Sirpa Jalkanen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Malko Salmi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. AKAHOSHI Noriyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAYASAKA Haruko 早坂 晴子

Research Projects

Research Products

Co-Researchers

麻酔薬圧拮抗作用の実時間イメージング

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Transcriptional regulation of angiogenesis and tissue differentiation in microenvironmentPrincipal Investigator

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Lymphatic transport of dietary flavonoids: elucidation of its driving force and physiological roles

Principal Investigator

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Mechanism of tissue-specific differentiation of vascular endothelial cells by Dach1 expressionPrincipal Investigator

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The mechanism underlying tumor inhibition by angiogenesis and immune cell recruitmentPrincipal Investigator

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Analysis of the transcription factor crosstalk in high endothelial venule formationPrincipal Investigator

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Characteristics and functions of stromal cells in secondary lymphoid tissues

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Understanding of the mechanism underlying the tissue-specific differentiation of high endothelial venule endothelial cellsPrincipal Investigator

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Integrative understanding of biological processes mediated by transient macromolecul ar complexes; New technology for visualizing physiologically metastable states

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Analysis of the conformational transitions and functional modifications in membrane proteinsPrincipal Investigator

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Elucidation of the mechanism underlying immune cell trafficking dependent on lysophospholipid signaling

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腫瘍血管へ免疫細胞動員活性を誘導する生体プログラムの賦活化と抗腫瘍免疫監視の強化

Principal Investigator

Project Period (FY)

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Stromal factors regulating tumor cell motility

Principal Investigator

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HAYASAKA Haruko 早坂晴子