Mizuno Dai 水野大

… Alternative Names

MIZUNO Dai 水野大

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Researcher Number	70380061
Other IDs
External Links
Affiliation (Current)	2025: 山形大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 山形大学, 医学部, 准教授 2015 – 2016: 山形大学, 医学部, 准教授 2014: 徳島大学, 疾患酵素学研究センター, 助教 2013 – 2014: 武蔵野大学, 薬学研究所, 講師 2010 – 2012: 徳島大学, 疾患酵素学研究センター, 助教 … More 2008: The University of Tokushima, 疾患酵素学研究センター, 助教 2007: The University of Tokushima, 病患酵素学研究センター, 科学技術振興教員 2006: 徳島大学, 分子酵素学研究センター, 科学技術振興教員 Less
Review Section/Research Field	Principal Investigator Virology / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Biomedical engineering/Biological material science Except Principal Investigator Infectious disease medicine / Environmental and hygienic pharmacy
Keywords	Principal Investigator 肺サーファクタント / ワクチン / インフルエンザ / 経鼻ワクチン / GT1-7細胞 / 神経毒性 / タリウム / 抗原デリバリー / 生体機能材料 / 粘膜免疫 / ペプチドワクチン / 感染防御 / ドラッグデリバリー … More Except Principal Investigator … More 多臓器不全 / 高病原性鳥インフルエンザ / Alzheimer / dementia / anserine / amyloid / Zn / ER stress / carnosine / HPLC / アポトーシス / 運動能力 / 抗酸化 / 肺疾患 / ARDS / カルシウムホメオスタシス / 神経細胞死 / 老年性認知症 / プリオン病 / アルツハイマー病 / 小胞体ストレス / カルシウム / 銅 / 亜鉛 / 神経毒性 / エネルギー代謝障害 / 血管内皮細胞機能障害 / プロテアーゼ阻害剤 / 代謝障害 / 季節性インフルエンザ / 重症化 / 血管透過性亢進 / エネルギー代謝 / 診断法 / バイオマーカー / 治療法 / 重症化機序 / インフルエンザ / 高病原も生鳥インフルエンザ / MMP-97 / ATP産生 / ミトコンドリア膜電位 / MMP-9 / トリプシン / サイトカインストーム / プロセシングプロテアーゼ Less

Study on the mechanism of toxicity induced by trivalent thallium on nerve cellsPrincipal Investigator
- Principal Investigator
  
  水野大
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Yamagata University
Neuroprotective mechanism of carnosine against zinc-induced neurotoxicity: a possible drug for vascular dementia
- Principal Investigator
  
  Kawahara Masahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Musashino University
Pathogenicity of multiple organ failure induced by seasonal and highly pathogenic avian influenza virus infection and its therapeutic options
- Principal Investigator
  
  KIDO Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Infectious disease medicine
- Research Institution
  The University of Tokushima
The application to cancer vaccine of SSF that mimics pulmonary surfactantPrincipal Investigator
- Principal Investigator
  
  MIZUNO Dai
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Musashino University
  The University of Tokushima
Development of a new nasal vaccine effective against many types of influenza that based on pulmonary surfactantPrincipal Investigator
- Principal Investigator
  
  MIZUNO Dai
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokushima
Development of new therapeutics for a highly pathogenic influenza virus infection by inhibition of virus entry and multiplication
- Principal Investigator
  
  KIDO Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Infectious disease medicine
- Research Institution
  The University of Tokushima
A novel adjuvant that based on pulmonaary surfactant.Principal Investigator
- Principal Investigator
  
  MIZUNO Dai
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokushima

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Patent

[Book] Metallomics-Recent Analytical Techniques and Applications-, (eds Ogra,Y and Hirata, T)2017
- Author(s)
  Mizuno D and Kawahara M
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26460177
[Book] Disruption of metal homeostasis and the pathogenesis of prion diseases Prion2016
- Author(s)
  Kawahara M, Tanaka K, and Mizuno D
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-26460177
[Book] Carnosine: Physiological Effects and Research Insights2016
- Author(s)
  Kawahara M, Tanaka K and Mizuno D
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-26460177
[Book] 18．薬事制度（医薬品・医療機器等の恩恵と被害）. 『生命倫理・医事法』 (分担著)2015
- Author(s)
  水野　大他
- Publisher
  医療科学社
- Data Source
  KAKENHI-PROJECT-24500527
[Book] Oligomerization (ed by Claire Lesieur, ISBN 980-953-307-1130-3)2014
- Author(s)
  Mizuno D and Kawahara M
- Total Pages
  450
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-26460177
[Book] Oligomerization of Chemical and Biological Compounds. (ISBN 980-953-307-1130-3)2014
- Author(s)
  Mizuno D and Kawahara M
- Publisher
  Lesieur C, InTech
- Data Source
  KAKENHI-PROJECT-24500527
[Book] ワクチン開発における最新動向～規制動向・安全性評価・品質管理・アジュバント・開発事例～( ISBN 980-953-307-1130-3)2013
- Author(s)
  水野　大　他
- Total Pages
  220
- Publisher
  株式会社情報機構
- Data Source
  KAKENHI-PROJECT-24500527
[Journal Article] Quantitative analysis of carnosine and anserine in foods by performing high performance liquid chromatography2015
- Author(s)
  Mori, D. Mizuno, K. Konoha-Mizuno, Y. Sadakane, M. Kawahara
- Journal Title
  
  Biomedical Research on Trace Elements
  
  Volume: 26 Pages: 49-53
- NAID
  130005113917
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460177
[Journal Article] Oral administration of Lactobacillus strain S-PT84 enhances anti-influenza virus specific IgG production in plasma after limited doses of ingluenza virus vaccination in mice.2015
- Author(s)
  Toshihiro Maekawa, Takashi Kimoto, Dai Mizuno, Yuichi Furukawa, Masayuki Ida, Etsuhisa Takahashi, Takayuki Izumo, Yoshiko Ono, Hiroshi Shibata, Hiroshi Kido
- Journal Title
  
  J. Vaccine and Immunol.
  
  Volume: 2(1) Pages: 5-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249059
[Journal Article] Protective activity of carnosine and anserine against zinc-induced neurotoxicity: a possible treatment for vascular dementia.2015
- Author(s)
  Mizuno D et al
- Journal Title
  
  Metallomics
  
  Volume: 印刷中 Issue: 8 Pages: 1-7
- DOI
  10.1039/c5mt00049a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500527, KAKENHI-PROJECT-26460177
[Journal Article] Carnosine concentration in the muscle of thoroughbred horses and its implications in exercise performance2015
- Author(s)
  M.Mori, D.Mizuno, K.Konoha-Mizuno, Y.Sadakane, M.Kawahara
- Journal Title
  
  Trace Nutrients Research
  
  Volume: 32 Pages: 49-53
- NAID
  40020919697
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460177
[Journal Article] 微量元素と神経疾患：シナプス間隙における疾患関連タンパクと金属との相互作用2015
- Author(s)
  川原正博、水野大
- Journal Title
  
  Biomed Trace Elem Res
  
  Volume: 26 Pages: 10-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460177
[Journal Article] Carnosine: A Possible Drug for Vascular Dementia.2014
- Author(s)
  Mizuno D et al.
- Journal Title
  
  J Vasc Med Surg
  
  Volume: 2 Issue: 03 Pages: 146-146
- DOI
  10.4172/2329-6925.1000146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500527, KAKENHI-PROJECT-26460177
[Journal Article] Involvement of trace elements in the pathogenesis of prion diseases.2014
- Author(s)
  Mizuno D et al.
- Journal Title
  
  Curr Pharm Biotech
  
  Volume: 15 Issue: 11 Pages: 1049-1057
- DOI
  10.2174/1389201015666141103020625
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500527
[Journal Article] ニューロメタルとアミロイド形成タンパク質のクロストーク2014
- Author(s)
  川原正博、水野大
- Journal Title
  
  日本衛生学雑誌
  
  Volume: 69 Pages: 155-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460177
[Journal Article] Involvement of trace elements in the pathogenesis of prion diseases2014
- Author(s)
  Mizuno D, Koyama H, Ohkawara S, Sadakane Y, Kawahara M
- Journal Title
  
  Curr Pharam Biotech
  
  Volume: 15 Pages: 1049-57
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460177
[Journal Article] 神経疾患と亜鉛2014
- Author(s)
  川原正博、定金豊、水野大
- Journal Title
  
  亜鉛栄養治療
  
  Volume: 5 Pages: 4-15
- NAID
  40020474970
- Data Source
  KAKENHI-PROJECT-26460177
[Journal Article] Intranasal influenza vaccination using a new synthetic mucosal adjuvant SF-10 –Induction of potent local and systemic immunity with balanced Th1 and Th2 responses2013
- Author(s)
  Takashi Kimoto 他
- Journal Title
  
  Influenza Other Respir. Viruses
  
  Volume: 7(6) Issue: 6 Pages: 1218-1226
- DOI
  10.1111/irv.12124
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-24500527
[Journal Article] The involvement of endoplasmic reticulum-stress in zinc neurotoxicity and the pathogenesis of vascular type senile dementia.2013
- Author(s)
  Mizuno D et al.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 14 Issue: 11 Pages: 22067-22081
- DOI
  10.3390/ijms141122067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500527
[Journal Article] Immunomodulator clarithromycin enhamces mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitor: A retrospective analysis.2013
- Author(s)
  Wakako Shinahara, Etsuhisa Takahashi, Takako Sawabuchi, Masaru Arai, Nobuo Hirotsu, Yoshio Takasaki, Shizuo Shindo, Kyoko Shibao, Takashi Yokoyama, Kiyoshi Nishikawa, Masahiro Mino, Minako Iwaya, Yuji Yamashita, Satoshi Suzuki, Dai Mizuno, Hiroshi Kido
- Journal Title
  
  PLoS ONE
  
  Volume: 8(7) Issue: 7 Pages: e70060-e70060
- DOI
  10.1371/journal.pone.0070060
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249059, KAKENHI-PROJECT-24500527
[Journal Article] Surfactant protein C is an essential constituent for mucosal adjuvanticity of Surfacten2011
- Author(s)
  Mizuno D et al.
- Journal Title
  
  acting as an antigen delivery vehicle and inducing both local and systemic immunity
  
  Volume: 29 Issue: 33 Pages: 5368-5378
- DOI
  10.1016/j.vaccine.2011.05.090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790433
[Journal Article] Surfactant protein C is an essential constituent for mucosal adjuvanticity of Surfacten, acting as an antigen delivery vehicle and inducing both local and systemic immunity2011
- Author(s)
  Mizuno D, et al
- Journal Title
  
  Vaccine
  
  Volume: 29 Pages: 5368-5378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790433
[Journal Article] 経鼻ワクチンの開発状況2010
- Author(s)
  木戸博、水野大、武井恒知
- Journal Title
  
  インフルエンザ
  
  Volume: 11(2) Pages: 184-190
- Data Source
  KAKENHI-PROJECT-21249061
[Journal Article] SP-Cはサーファクテンによる経鼻ワクチン増強効果の必須成分である2010
- Author(s)
  水野大
- Journal Title
  
  日本肺サーファクタント・界面医学会雑誌
  
  Volume: 41 Pages: 32-33
- NAID
  10027729517
- Data Source
  KAKENHI-PROJECT-22790433
[Journal Article] SP-Cはサーファクテンによる経鼻ワクチン増感効果の必須成分である2010
- Author(s)
  水野大
- Journal Title
  
  日本肺サーファクタント・界面医学会雑誌
  
  Volume: 41 Pages: 32-33
- Data Source
  KAKENHI-PROJECT-22790433
[Journal Article] 粘膜免疫機能とインフルエンザ感染2010
- Author(s)
  木戸博、水野大, 、木本貴士
- Journal Title
  
  小児内科
  
  Volume: 42(9) Pages: 1541-1545
- Data Source
  KAKENHI-PROJECT-21249061
[Journal Article] Evaluation of nasal IgA secretion in normal subjects by nasal spray and aspiration.,2009
- Author(s)
  Fujimooto C, Kido H, Shawabuchi T, Mizuno D, Hayama M, Yanagawa H, Takeda N,
- Journal Title
  
  Auris Nasus Larynx., 6
  
  Pages: 300-3004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790323
[Journal Article] 経鼻投与型インフルエンザワクチン2008
- Author(s)
  木戸博,水野大,武井恒知
- Journal Title
  
  総合臨床 57
  
  Pages: 2628-2633
- Data Source
  KAKENHI-PROJECT-18790323
[Journal Article] Nasal vaccines2008
- Author(s)
  Kido H, Mizuno D, Takei T,
- Journal Title
  
  Nippon Rinsho. 66
  
  Pages: 1881-1887
- NAID
  40016245316
- Data Source
  KAKENHI-PROJECT-18790323
[Journal Article] Modified pulmonary surfactant is a potent adjuvant that stimulates the mucosal IgA production in response to the influenza Virus Antigen.2006
- Author(s)
  Mizuno D, Kubo I, Ide M, Ichinomiya T, Kido H
- Journal Title
  
  Journal of Immunology, 176
  
  Pages: 1122-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790323
[Journal Article] 肺サーファクタントの粘膜アジュバント作用2006
- Author(s)
  木戸博,水野大,西野真紀臼木孝行,武井恒知
- Journal Title
  
  臨床免疫・アレルギー科 46
  
  Pages: 411-415
- NAID
  40015165770
- Data Source
  KAKENHI-PROJECT-18790323
[Journal Article] A novel adjuvant for mucosal immunization, Surfacten, a modified pulumonary surfactant preparation, stimulates antigen specific mucosal IgA production in the airway.2006
- Author(s)
  Mizuno D
- Journal Title
  
  Journal of Immunology 176
  
  Pages: 1122-1130
- Data Source
  KAKENHI-PROJECT-18790323
[Patent] 経粘膜及び経皮投与を可能にする抗原薬物ビークル、これを用いる粘膜免疫の誘導方法、粘膜ワクチン及びDDS。2011
- Inventor(s)
  木戸博,水野大
- Industrial Property Rights Holder
  国立大学法人徳島大学
- Acquisition Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22790433
[Patent] RSV粘膜ワクチン。2011
- Inventor(s)
  木戸博,水野大,武井恒知,上田博嗣,吉川浩司,大隅恵介,山本伸行,周藤健治
- Industrial Property Rights Holder
  国立大学法人徳島大学、株式会社応用酵素医学研究所、アステラス製薬株式会社
- Industrial Property Number
  2011-185873
- Filing Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-22790433
[Patent] 局所粘膜免疫誘導促進用抗原薬物ヴィークル、これを用いる粘膜ワクチン、アレルギーの予防剤又は治療剤、薬物伝達システム、および粘膜免疫の誘導法。2010
- Inventor(s)
  木戸博,武井恒知,水野大
- Industrial Property Rights Holder
  国立大学法人徳島大学
- Acquisition Date
  2010-11-01
- Data Source
  KAKENHI-PROJECT-22790433
[Presentation] 食品中カルノシンのcarbon カラムHPLC による定量分析2017
- Author(s)
  田中健一郎, 森美和子, 水野大, 定金豊, 川原正博
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] Metal-metal interactions in zinc-induced neurotoxicity: the possible involvements in the pathogenesis of vascular dementia2016
- Author(s)
  Kawahara M, Mizuno D, Tanaka K.
- Organizer
  Neuroscience 2016
- Place of Presentation
  SanDiegoConvention center (San Diego, U.S.A.)
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] 食品中カルノシンおよびアンセリンのHPLCによる定量分析2016
- Author(s)
  桒原奈緒美、森　美和子、水野　大、田中健一郎、川原正博
- Organizer
  第33回日本微量栄養素学会学術集会
- Place of Presentation
  京都リサーチパーク（京都）
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] カルノシンおよびアンセリンのHPLCによる定量分析およびその神経保護作用機構の解析2015
- Author(s)
  森美和子、水野大、定金豊、川原正博
- Organizer
  第28回バイオメディカル分析化学シンポジウム
- Place of Presentation
  長崎大学（長崎）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] カルノシンによる神経細胞保護メカニズムの解析2015
- Author(s)
  川原正博、水野大
- Organizer
  日本微量元素学会
- Place of Presentation
  北海道大学（札幌）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] カルノシンの神経保護作用及び筋肉中含量の解析2015
- Author(s)
  森美和子、木葉―水野敬子、水野大、定金豊、川原正博
- Organizer
  第32回日本微量栄養素学会
- Place of Presentation
  京都
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] 筋肉中カルノシンおよびアンセリンの順相HPLCによる定量分析2015
- Author(s)
  森美和子、水野大、水野－木葉敬子、定金豊、川原正博
- Organizer
  新アミノ酸分析研究会
- Place of Presentation
  東京大学（東京）
- Year and Date
  2015-12-07
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] Molecular Mechanism of Neuroprotective activity by Carnosine and Anserine2015
- Author(s)
  Mizuno D, Mori M, Asakawa N, Murohisa K, Yamamoto R, and Kawahara M
- Organizer
  第25回金属の関与する生体関連反応シンポジウム(SRM2015)
- Place of Presentation
  長崎大学（長崎）
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] アロマテラピー精油のGT1-7細胞 (不死化視床下部神経細胞) に対する影響2014
- Author(s)
  水野　大　他
- Organizer
  第134回日本薬学会年会
- Place of Presentation
  熊本市総合体育館（熊本）
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] カルノシン、アンセリン類の順相HPLCによる分離分析およびその神経細胞死抑制機構の解析2014
- Author(s)
  水野　大、菅亜由美、小林清美、小山裕也、定金豊、川原正博
- Organizer
  第4回新アミノ酸分析研究会
- Place of Presentation
  東京大学（東京都）
- Year and Date
  2014-11-17
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] 金属が脳内アミロイド蛋白のコンフォメーション変化及び神経毒性に及ぼす影響2014
- Author(s)
  川原正博、水野大
- Organizer
  第41回日本毒性学会学術年会シンポジウム
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2014-07-02
- Invited
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] 脳血管認知症予防・治療薬としてのカルノシンの作用メカニズム解析2014
- Author(s)
  水野　大　他
- Organizer
  第134回日本薬学会年会
- Place of Presentation
  熊本市総合体育館（熊本）
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] Effects of carnosine on Zinc-induced neurotoxicity and its analysis in rat’s brain2013
- Author(s)
  Mizuno D et al.
- Organizer
  International Society For Trance Element Reserch in Humans 2013
- Place of Presentation
  Keio Plaza Hotel (Tokyo)
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] 人工サーファクタントSF10による経鼻インフルエンザワクチンアジュバント効果2013
- Author(s)
  水野　大　他
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  帝京大学板橋キャンパス（東京）
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] 亜鉛による神経細胞死のカルノシン抑制機構の検討2013
- Author(s)
  水野　大　他
- Organizer
  第26回バイオメディカル分析科学シンポジウム
- Place of Presentation
  昭和大学旗の台キャンパス（東京）
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] カニクイザルを用いた、ヒト肺サーファクタント由来SF-10アジュバントによる経鼻インフルエンザワクチンの効果検討2012
- Author(s)
  水野大他
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場 (福岡県)
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] カニクイザルを用いた、ヒト肺サーファクタント由来SF-10アジュバントによる経鼻インフルエンザワクチンの効果検討2012
- Author(s)
  水野大他
- Organizer
  第16回日本ワクチン学会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] Synthetic antigen vehicle SF-10 adjuvant, mimicking human pulmonary surfactant, for effective intranasal flu vaccine2011
- Author(s)
  Mizuno D
- Organizer
  nternational Union of Microbiological Societies 20
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-22790433
[Presentation] 肺サーファクタント由来人工合成粘膜アジュバントSF10の開発と抗体誘導効果の検討2011
- Author(s)
  水野大
- Organizer
  第47回肺サーファクタント界面医学会
- Place of Presentation
  徳島大学(徳島県)
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-22790433
[Presentation] Synthetic antigen vehicle SF-10 adjuvant, mimicking human pulmonary surfactant2011
- Author(s)
  Mizuno D
- Organizer
  or effective intranasal flu vaccine International Union of Microbiological Societies 2011
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-22790433
[Presentation] 人工粘膜アジュバントSF10による経鼻インフルエンザワクチンの局所と全身の抗体誘導効果の検討2010
- Author(s)
  水野大
- Organizer
  第33回日本分子生物学会年回・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790433
[Presentation] 人工合成粘膜アジュバントSF10による経鼻インフルエンザワクチンの局所と全身の抗体誘導効果の検討2010
- Author(s)
  水野大
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-22790433
[Presentation] 人工合成ヒト肺サーファクタントプロテインCのアジュバント活性に必要なペプチド配列の探索2008
- Author(s)
  (木本貴士),水野大,編田明穂,武井恒知,品原和加子,木戸博
- Organizer
  第81回日本生化学会大会・第31回日本分子生物学会年会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-18790323
[Presentation] インフルエンザ感染を左右する気道粘膜免疫の重要性と,生体成分粘膜ワクチンアジュバントを用いた経鼻ワクチン開発2008
- Author(s)
  木戸博,(福田明穂),木本貴士,武井恒知,品原和加子,水野大
- Organizer
  第12回日本ワクチン学会学術集会
- Place of Presentation
  熊本
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-18790323
[Presentation] SP-C is the essential component for theadjuvanticity of Surfacten,2007
- Author(s)
  (Mizuno D), Takei T, Nishino M, Shinahara W, Kimoto T, Fukuda A, Kido H,
- Organizer
  第30回日本分子生物学学会年会・第80回生化学会大会
- Place of Presentation
  神奈川
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18790323
[Presentation] SP-C is the essential component for the adjuvanticity of Surfacten.2007
- Author(s)
  水野大
- Organizer
  第30回日本分子生物学学会年会・第80回生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-18790323
[Presentation] Modified pulmonary surfactant is a novel antigen vehicle for influenza virus antigen to nasal-associated lymphoidtissues.2006
- Author(s)
  (Mizuno D), Ide-Kurihara M, Ichinomiya T, Kubo I, Takei T, Nishino M, Usuld. T, Kido H
- Organizer
  20th International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  京都
- Year and Date
  2006-06-20
- Data Source
  KAKENHI-PROJECT-18790323
[Presentation] アロマテラピー精油in vitro 機能評価系の開発,
- Author(s)
  水野　大他
- Organizer
  第27回バイオメディカル分析科学シンポジウム
- Place of Presentation
  帝京大学(東京)
- Year and Date
  2014-08-20 – 2014-08-21
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] 亜鉛による神経細胞死メカニズムの検討
- Author(s)
  川原正博、水野大
- Organizer
  日本微量元素学会第25回年会シンポジウム「ジンクシグナリングの最前線」
- Place of Presentation
  岡山大学（岡山市）
- Year and Date
  2014-07-03 – 2014-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] Involvement of endoplasmic reticulum stress and calcium dyshomeostasis in zinc-induced neurotoxicity
- Author(s)
  Dai MIZUNO and Masahiro KAWAHARA
- Organizer
  Neuroscience2014(Society for Neuroscience Meeting)
- Place of Presentation
  Convention Center（Washington DC, U.S.A.）
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] 日本の予防接種制度を、予防接種禍から考える
- Author(s)
  水野　大
- Organizer
  日本社会医療学会第15回記念大会
- Place of Presentation
  九州保健福祉大学(宮崎)
- Year and Date
  2014-10-18 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-24500527
[Presentation] 神経疾患と微量元素
- Author(s)
  川原正博、水野大
- Organizer
  日本微量元素学会第25回年会シンポジウム「疾患と微量元素」
- Place of Presentation
  岡山大学（岡山市）
- Year and Date
  2014-07-03 – 2014-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-26460177
[Presentation] 亜鉛神経細胞死におけるカルノシンの役割
- Author(s)
  水野大、菅亜由美、川原正博
- Organizer
  第24回金属の関与する生体関連反応シンポジウム（SRM2014）
- Place of Presentation
  京都薬科大学（京都）
- Year and Date
  2014-06-17 – 2014-06-18
- Data Source
  KAKENHI-PROJECT-26460177

1. KIDO Hiroshi (50144978)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. CHIDA Junji (20437651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. YOUSSOUF Cisse (80437649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. CHIDA Junji (10437651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Kawahara Masahiro (40224828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results

Mizuno Dai 水野 大

MIZUNO Dai 水野 大

Research Projects

Research Products

Co-Researchers

Study on the mechanism of toxicity induced by trivalent thallium on nerve cellsPrincipal Investigator

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Neuroprotective mechanism of carnosine against zinc-induced neurotoxicity: a possible drug for vascular dementia

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Pathogenicity of multiple organ failure induced by seasonal and highly pathogenic avian influenza virus infection and its therapeutic options

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The application to cancer vaccine of SSF that mimics pulmonary surfactantPrincipal Investigator

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Development of a new nasal vaccine effective against many types of influenza that based on pulmonary surfactantPrincipal Investigator

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Development of new therapeutics for a highly pathogenic influenza virus infection by inhibition of virus entry and multiplication

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A novel adjuvant that based on pulmonaary surfactant.Principal Investigator

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[Book] Metallomics-Recent Analytical Techniques and Applications-, (eds Ogra,Y and Hirata, T)2017

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[Book] Disruption of metal homeostasis and the pathogenesis of prion diseases Prion2016

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[Book] Carnosine: Physiological Effects and Research Insights2016

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[Book] 18．薬事制度（医薬品・医療機器等の恩恵と被害）. 『生命倫理・医事法』 (分担著)2015

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[Book] Oligomerization (ed by Claire Lesieur, ISBN 980-953-307-1130-3)2014

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[Book] Oligomerization of Chemical and Biological Compounds. (ISBN 980-953-307-1130-3)2014

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[Book] ワクチン開発における最新動向～規制動向・安全性評価・品質管理・アジュバント・開発事例～( ISBN 980-953-307-1130-3)2013

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[Journal Article] Quantitative analysis of carnosine and anserine in foods by performing high performance liquid chromatography2015

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Journal Title

Mizuno Dai 水野大

MIZUNO Dai 水野大