Nakashima Akio 中嶋昭雄

… Alternative Names

中嶋昭雄ナカシマアキオ

NAKASHIMA Akio 中嶋昭雄

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Researcher Number	70397818
Other IDs
Affiliation (Current)	2025: 神戸大学, バイオシグナル総合研究センター, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 神戸大学, バイオシグナル総合研究センター, 准教授 2015 – 2020: 神戸大学, バイオシグナル総合研究センター, 准教授 2017: 神戸大学, 学内共同利用施設等, 研究員 2016: 神戸大学, バイオシグナル総合研究センター, 助教 2015: 神戸大学, バイオシグナル研究センター, 准教授 … More 2014: 神戸大学, バイオシグナル研究センター, 助教 2012: 神戸大学, 自然科学系先端融合研究環, バイオシグナル研究センター 2010 – 2012: 神戸大学, 自然科学系先端融合研究環バイオシグナル研究センター, 助教 2010: 神戸大学, 自然科学系先端融合研究環・バイオシグナル研究センター, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Functional biochemistry / Cell biology Except Principal Investigator Basic Section 42010:Animal production science-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Animal production science / Tumor biology / General medical chemistry
Keywords	Principal Investigator 分裂酵母 / 減数分裂 / TORC1 / シグナル伝達 / 選択的オートファジー / オートファジー / モデル生物 / 細胞制御 / 栄養 / 細胞機能制御 / 栄養応答 / TOR … More Except Principal Investigator … More ウシ / 人工授精 / 精子 / 応用動物 / 鞭毛運動 / 雄性繁殖能力 / 雄性繁殖学 / 畜産学 / 応用動物学 / 分子性状検査法 / アミノ酸代謝 / 活性酸素 / p53 / DNA損傷 / 細胞老化 / STAT3 / Rheb / TIP41 / PP242 / アミノ酸 / mTIP41 / AMPK / ラパマイシン / ホスファターゼ / 栄養 / mTOR / シグナル伝達 Less

Establishment and spread of the new assay for sperm flagellar function to improve artificial insemination results in the cattle
- Principal Investigator
  
  原山洋
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Kobe University
減数分裂におけるTORC1キナーゼおよびオートファジーの機能制御の分子機構Principal Investigator
- Principal Investigator
  
  中嶋昭雄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kobe University
Analyses of 3-dimensional rotation for the purpose of reconsidering criteria for the evaluation of flagellar functions in bull sperm
- Principal Investigator
  
  HARAYAMA HIROSHI
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Kobe University
Characterization and utilization of SPACA1 proteins for the purpose of establishment of a new method to predict freezability of bull sperm before cryopreservation
- Principal Investigator
  
  HARAYAMA HIROSHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  Kobe University
Molecular mechanism of TORC1 activity and function in meiosis using a model organism.Principal Investigator
- Principal Investigator
  
  Nakashima Akio
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
Identification and characterization of cellular senescence-specific genes
- Principal Investigator
  
  Kamada Shinji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Kobe University
Molecular mechanism of the signaling involved in nutrient sensing and cell regulation that mediated by TORC1 in fission yeastPrincipal Investigator
- Principal Investigator
  
  NAKASHIMA Akio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Kobe University
Regulation mechanisms of mTOR-mediated nutrient signaling by protein phosphatase PP2A
- Principal Investigator
  
  KIKKAWA Ushio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University

All 2023 2022 2017 2016 2015 2014 2013 2012 2011 2010 2008 Other

All Journal Article Presentation

[Journal Article] TORC1-Dependent Phosphorylation Targets in Fission Yeast2017
- Author(s)
  Otsubo Yoko、Nakashima Akio、Yamamoto Masayuki、Yamashita Akira
- Journal Title
  
  Biomolecules
  
  Volume: 7 Issue: 3 Pages: 50-50
- DOI
  10.3390/biom7030050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18542, KAKENHI-PROJECT-15H04333, KAKENHI-PROJECT-15J40037, KAKENHI-PROJECT-26440053
[Journal Article] Proline dehydrogenase promotes senescence through the generation of reactive oxygen species.2017
- Author(s)
  Nagano T, Nakashima A, Onishi K, Kawai K, Awai Y, Kinugasa M, Iwasaki T, Kikkawa U, Kamada S.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 130 Issue: 8 Pages: 1413-1420
- DOI
  10.1242/jcs.196469
- NAID
  120006462307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15595, KAKENHI-PROJECT-26440053
[Journal Article] The loss of Lam2 and Npr2-Npr3 diminishes the vacuolar localization of Gtr1-Gtr2 and disinhibits TORC1 activity in fission yeast.2016
- Author(s)
  Ma N, Ma Y, Nakashima A, Kikkawa U, Furuyashiki T.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 5 Pages: e0156239-e0156239
- DOI
  10.1371/journal.pone.0156239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01289, KAKENHI-PROJECT-16H05132, KAKENHI-PROJECT-26460339, KAKENHI-PROJECT-26440053
[Journal Article] Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation.2016
- Author(s)
  Kozel C, Thompson B, Hustak S, Moore C, Nakashima A, Singh CR, Reid M, Cox C, Papadopoulos E, Luna RE, Anderson A, Tagami H, Hiraishi H, Slone EA, Yoshino KI, Asano M, Gillaspie S, Nietfeld J, Perchellet JP, Rothenburg S, Masai H, Wagner G, Beeser A, Kikkawa U, Fleming SD, Asano K.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 44 Issue: 18 Pages: 8704-8713
- DOI
  10.1093/nar/gkw559
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440053, KAKENHI-PROJECT-26251004
[Journal Article] Versatile function of the circadian protein CIPC as a regulator of Erk activation.2016
- Author(s)
  Matsunaga R., Nishino T., Yokohama A., Nakashima A., Kikkawa U., and Konishi H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469 Issue: 3 Pages: 377-383
- DOI
  10.1016/j.bbrc.2015.11.117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440053, KAKENHI-PROJECT-26440060
[Journal Article] Identification of cellular senescence-specific genes by comparative transcriptomics2016
- Author(s)
  Nagano T, Nakano M, Nakashima A, Onishi K, Yamao S, Enari M, Kikkawa U, Kamada S
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 31758-31758
- DOI
  10.1038/srep31758
- NAID
  120005842606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04702, KAKENHI-PROJECT-16J09279, KAKENHI-PROJECT-26440053
[Journal Article] Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family.2015
- Author(s)
  Kawai M., Nakashima A., Kamada S., and Kikkawa U.
- Journal Title
  
  J Biomed. Sci.
  
  Volume: 22 Issue: 1 Pages: 48-48
- DOI
  10.1186/s12929-015-0150-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440053, KAKENHI-PROJECT-25640063
[Journal Article] Fission yeast arrestin-related trafficking adaptor, Arn1/Any1, is ubiquitinated by Pub1 E3 ligase and regulates endocytosis of Cat1 amino acid transporter.2014
- Author(s)
  Nakashima, A., Kamada, S., Tamanoi, F., and Kikkawa, U.
- Journal Title
  
  Biol. Open
  
  Volume: 3 Issue: 6 Pages: 542-552
- DOI
  10.1242/bio.20148367
- NAID
  120005460282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25640063, KAKENHI-PROJECT-26440053
[Journal Article] Identification of Regions Critical for the Integrity of the TSC1-TSC2-TBC1D7 Complex.2014
- Author(s)
  Santiago, Lima, A.J., Hoogeveen-Westerveld, M., Nakashima, A., Maat-Kievit, A., van den Ouweland, A., Halley, D., Kikkawa, U., and Nellist, M.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 4 Pages: e93940-e93940
- DOI
  10.1371/journal.pone.0093940
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440053
[Journal Article] Association of CAD, a multifunctional protein involved in pyrimidine synthesis, with mLST8, a component of the mTOR complexes2013
- Author(s)
  Nakashima A, Kawanishi I, Eguchi S, Yu EH, Eguchi S, Oshiro N, Yoshino K, Kikkawa U, Yonezawa K.
- Journal Title
  
  Journal of Biomedical Science
  
  Volume: 20 Issue: 1 Pages: 24-24
- DOI
  10.1186/1423-0127-20-24
- NAID
  120005460275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770229, KAKENHI-PROJECT-24770115
[Journal Article] Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein.2013
- Author(s)
  Nakano, M., Nakashima A., Nagano, T., Ishikawa, S., Kikkawa, U., and Kamada, S.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 11 Pages: e80411-e80411
- DOI
  10.1371/journal.pone.0080411
- NAID
  120005465549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640063
[Journal Article] A positive role of mammalian Tip41-like protein, TIPRL, in the amino-acid dependent mTORC1-signaling pathway through interaction with PP2A2013
- Author(s)
  Nakashima, A., Tanimura-Ito, K., Oshiro, N., Eguchi, S., Miyamoto, K., Momonami, A., Kamada, S., Kikkawa, U. and Yonezawa, K.
- Journal Title
  
  FEBS letter
  
  Volume: 587 Issue: 18 Pages: 2924-2929
- DOI
  10.1016/j.febslet.2013.07.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770115, KAKENHI-PROJECT-25640063
[Journal Article] Cyclin I is involved in the regulation of cell cycle progression.2013
- Author(s)
  Nagano et al.
- Journal Title
  
  Cell Cycle
  
  Volume: 12 Issue: 16 Pages: 2617-2624
- DOI
  10.4161/cc.25623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290024, KAKENHI-PROJECT-25640063
[Journal Article] Psk1, an AGC kinase family member in fission yeast, is directly phosphorylated and controlled by TORC1 and functions as S6 kinase.2012
- Author(s)
  Akio Nakashima
- Journal Title
  
  Journal of Cell Science
  
  Volume: 125 Issue: 23 Pages: 5840-5849
- DOI
  10.1242/jcs.111146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21227007, KAKENHI-PROJECT-23770229
[Journal Article] Preferential Fas-mediated apoptotic execution at G1 phase: the resistance of mitotic cells to the cell death.2012
- Author(s)
  Hashimoto T, Juso K, Nakano M, Nagano T, Kambayashi S, Nakashima A, Kikkawa U, and Kamada S.
- Journal Title
  
  Cell Death and Disease
  
  Volume: 3 Issue: 5 Pages: e313-e313
- DOI
  10.1038/cddis.2012.52
- NAID
  120005465551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770229
[Journal Article] X-linked inhibitor of apoptosis protein mediates neddylation by itself but does not function as a NEDD8-E3 ligase for caspase-7.2012
- Author(s)
  Nagano T, Hashimoto T, Nakashima A, Kikkawa U, and Kamada S.
- Journal Title
  
  FEBS Letters
  
  Volume: 586 Issue: 11 Pages: 1612-1616
- DOI
  10.1016/j.febslet.2012.04.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770229
[Journal Article] アミノ酸センシングシステムとしてのmTOR複合体１の機序2011
- Author(s)
  原　賢太, 中嶋昭雄, 吉川　潮
- Journal Title
  
  実験医学
  
  Volume: ２９巻 Pages: 865-870
- Data Source
  KAKENHI-PROJECT-23770229
[Journal Article] アミノ酸センシングシステムとしてのmTOR 複合体1の機序2010
- Author(s)
  原賢太、中嶋昭雄、吉川潮
- Journal Title
  
  実験医学
  
  Volume: Vol. 29 Pages: 865-870
- Data Source
  KAKENHI-PROJECT-23770229
[Journal Article] AMP-activated protein kinase phosphorylates Golgi-specific brefeldin A resistance factor 1 at Thr1337 to induce disassembly of Golgi apparatus.2008
- Author(s)
  Miyamoto, T., Oshiro, N., Yoshino, K., Nakashima, A., Eguchi, S., Takahashi, M., Ono, Y., Kikkawa, U., Yonezawa, K.
- Journal Title
  
  J.Biol.Chem. 283(7)
  
  Pages: 4430-4438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase.2008
- Author(s)
  Nakashima, A., Maruki, Y., Imamura, Y., Kondo, C., Kawamata, T., Kawanishi, I., Takata, H., Matsuura, A., Lee, K.S., Kikkawa, U., Ohsumi, Y., Yonezawa, K., Kamada, Y.
- Journal Title
  
  PLoS ONE 3(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Journal Article] The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase.2008
- Author(s)
  Nakashima, A.
- Journal Title
  
  PLoS ONE 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] 分裂酵母TORC1の減数分裂過程における制御機構2023
- Author(s)
  中嶋昭雄，三笠瑛里華，杉原真子，岡久萌菜，宮本由衣，松田真弥
- Organizer
  第５６回酵母遺伝学フォーラム, 新潟大学五十嵐キャンパス
- Data Source
  KAKENHI-PROJECT-22K06127
[Presentation] 分裂酵母の減数分裂におけるTORC1とオートファジーの制御2023
- Author(s)
  中嶋昭雄，門脇有哉，宇田晴香，山下紗夕美，三笠瑛里華，杉原真子
- Organizer
  第13回TOR研究会, 千葉大学松韻会館
- Data Source
  KAKENHI-PROJECT-22K06127
[Presentation] 減数分裂過程におけるオートファジーの制御機構及び生理的役割2023
- Author(s)
  門脇有哉，宇田晴香，谷本茉結，宮迫剛士，山下紗夕美，中嶋昭雄
- Organizer
  第46回日本分子生物学会年会, 神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-22K06127
[Presentation] 分裂酵母の減数分裂におけるオートファジー制御2023
- Author(s)
  門脇有哉，山下紗夕美，宇田晴香，中嶋昭雄
- Organizer
  第５６回酵母遺伝学フォーラム, 新潟大学五十嵐キャンパス
- Data Source
  KAKENHI-PROJECT-22K06127
[Presentation] 分裂酵母おける減数分裂進行に伴うオートファジーの発生と役割について2022
- Author(s)
  山下紗夕美, 宇田晴香, 中嶋昭雄（神戸大, 院農, 資源生命科学, 神戸大, バイオシグナル）
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06127
[Presentation] 分裂酵母の減数分裂におけるTORC1活性とオートファジー2022
- Author(s)
  中嶋昭雄, 宇田晴香, 山下紗夕（神戸大, 院農, 資源生命科学, 神戸大, バイオシグナル）
- Organizer
  第１２回TOR研究会
- Data Source
  KAKENHI-PROJECT-22K06127
[Presentation] 減数分裂における分裂酵母TORC1の制御2017
- Author(s)
  中嶋　昭雄
- Organizer
  ConBio2017（生命科学系学会合同年次大会）, 神戸市ポートアイランド
- Invited
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] フェロモン応答シグナルによる分裂酵母TORC1 制御の可能性2016
- Author(s)
  中嶋昭雄，吉川潮
- Organizer
  第６回ＴＯＲ研究会
- Place of Presentation
  東京大学分子細胞生物学研究所 (東京都・文京区）
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] 減数分裂における分裂酵母TORC1 の制御と機能2015
- Author(s)
  中嶋　昭雄; 吉川　潮
- Organizer
  第５回TOR研究会
- Place of Presentation
  新潟大学脳研究所（新潟県・新潟市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] Regulation of TORC1 signaling in meiosis under nitrogen starvation2015
- Author(s)
  Nakashima Akio; Yamashita Akira; Otsubo Yoko; Kamada Shinji; Uritani Masahiro; Yamamoto Masayuki; Kikkawa Ushio
- Organizer
  THE EIGHTH INTERNATIONAL FISSION YEAST MEETING
- Place of Presentation
  Kobe, Japan（兵庫県・神戸市）
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] 減数分裂における分裂酵母TORC1の制御と機能2015
- Author(s)
  中嶋　昭雄; 山下　朗; 大坪瑶子; 鎌田　真司; 瓜谷　眞裕; 山本　正幸; 吉川　潮
- Organizer
  Biochemistry and Molecular Biology 2015
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] 減数分裂における分裂酵母TORC1の制御と機能2015
- Author(s)
  中嶋昭雄、山下郎、大坪瑶子、鎌田真司、瓜谷眞裕、山本正幸、吉川潮
- Organizer
  第３８回日本分子生物学会、第８８回日本生化学会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] 多機能性 TORC1 キナーゼの液胞依存性栄養シグナルによる活性制御システムの解明2014
- Author(s)
  中嶋　昭雄
- Organizer
  第186回酵母細胞研究会例会平成24年度地神芳文記念研究助成金研究成果報告会
- Place of Presentation
  キリンビール（株）横浜工場
- Year and Date
  2014-07-11
- Invited
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] 細胞老化制御に関与する遺伝子の同定と機能解析2013
- Author(s)
  大西　健悟、長野　太輝、山尾　俊介、中嶋　昭雄、吉川　潮、鎌田　真司
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] Cyclin Iは細胞周期の進行に関与している2013
- Author(s)
  長野　太輝、橋本　季明、中嶋　昭雄、久永　眞市、吉川　潮、鎌田　真司
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] 分裂酵母TORC1 とオートファジーの相互関係2013
- Author(s)
  中嶋昭雄、吉川潮
- Organizer
  第二回TOR研究会
- Place of Presentation
  神戸大学
- Year and Date
  2013-03-14
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] The determination of cell fates to premature senescence and apoptosis by the phosphorylation level of p532012
- Author(s)
  Masayuki Nakano, Taiki Nagano, Akio Nakashima, Toshiaki Hashimoto, Masato Enari, Ushio Kikkawa, Shinji Kamada
- Organizer
  Molecular Genetics of Aging 2012, Cold Spring Harbor Meeting
- Place of Presentation
  Cold Spring Harbor, NY USA
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] アミノ酸トランスポーターCat1 のアレスチン様タンパク質による機能制御2012
- Author(s)
  中嶋昭雄、玉野井冬彦、吉川潮
- Organizer
  第45回酵母遺伝学フォーラム研究報告会
- Place of Presentation
  京都大学宇治キャンパスおうばくプラザ
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] 分裂酵母アレスチン様タンパク質Arn1 とそのユビキチン化を介したアミノ酸の細胞内取り込みの制御2012
- Author(s)
  中嶋昭雄, 玉野井冬彦, 吉川潮
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] Mammalian TIP41-like protein, mTIP41, as a positive regulator of the amino acid-stimulated mTORC1 signaling2011
- Author(s)
  Akio Nakashima, Ayaka Momonami, Noriko Oshiro, Ushio Kikkawa
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] アレスチン様タンパク質Art1 によるアミノ酸トランスポーターCat1 の機能制御2011
- Author(s)
  中嶋昭雄、吉川潮、玉野井冬彦
- Organizer
  第44回酵母遺伝学フォーラム研究報告会
- Place of Presentation
  九州大学医学部百年講堂
- Year and Date
  2011-09-05
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] 分裂酵母TORC1によるS6キナーゼPsk1の制御2010
- Author(s)
  中嶋昭雄
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20390081
[Presentation] 分裂酵母における栄養応答性TORC1の標的分子ならびにアミノ酸の細胞内取り込みに関わるアレスチン様分子の解析
- Author(s)
  中嶋昭雄
- Organizer
  第一回TOR研究会
- Place of Presentation
  静岡大学
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] プロリン脱水素酵素（PRODH）は細胞老化誘導に関わる新規因子である
- Author(s)
  長野　太輝、山尾　俊介、中嶋　昭雄、吉川　潮、鎌田　真司
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] Cell cycle dependency of apoptotic execution
- Author(s)
  Katsuya Juso, Toshiaki Hashimoto, Akio Nakashima, Ushio KIkkawa, Shinji Kamada
- Organizer
  第34回日本分子生物学会年会（BMSJ2011）
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] Possible interactions between the machineries of apoptosis and cell cycle progression
- Author(s)
  Shinji Kamada, Toshiaki Hashimoto, Akio Nakashima, Ushio Kikkawa
- Organizer
  2011 Taiwan-Japan Joint Symposium on Cell Signaling and Gene Regulation
- Place of Presentation
  Taiwan
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] 分裂酵母 TORC1 の減数分裂における活性化と機能の検討
- Author(s)
  中嶋　昭雄、吉川　潮
- Organizer
  第４回TOR研究会
- Place of Presentation
  基礎生物学研究所
- Year and Date
  2014-09-17 – 2014-09-18
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] 分裂酵母 TORC1 の窒素源飢餓時の再活性化と生理機能
- Author(s)
  中嶋　昭雄、吉川　潮
- Organizer
  第47回酵母遺伝学フォーラム報告会
- Place of Presentation
  東京大学農学部弥生キャンパス東京大学弥生講堂
- Year and Date
  2014-09-01 – 2014-09-02
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] 分裂酵母アレスチン様タンパク質Arn1とそのユビキチン化を介したアミノ酸の細胞内取り込みの制御
- Author(s)
  中嶋昭雄, 玉野井冬彦, 吉川潮
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] The determination of cell fates to premature senescence and apoptosis by the cellular levels of DNA damage
- Author(s)
  Masayuki Nakano, Akio Nakashima, Toshiaki Hashimoto, Masato Enari, Ushio KIkkawa, Shinji Kamada
- Organizer
  第34回日本分子生物学会年会（BMSJ2011）
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] 細胞老化制御に対する分岐鎖アミノ酸 BCAAs (Branched-Chain Amino Acids) の役割
- Author(s)
  中野真行, 中嶋昭雄, 吉川潮, 鎌田真司
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] p53のリン酸化状態の違いによる細胞老化とアポトーシスの運命決定制御機構
- Author(s)
  中野真行, 長野太輝, 大西健吾, 中嶋昭雄, 橋本季明, 江成政人, 吉川潮, 鎌田真司
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] X-linked inhibitor of apoptosis proteinは自身のNedd化は引き起こすが、caspase-7のNEDD8-E3 リガーゼとしては働かない
- Author(s)
  長野太輝, 橋本季明, 中嶋昭雄, 吉川潮, 鎌田真司
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] Mammalian TIP41-like protein, mTIP41, as a positive regulator of the amino acid-stimulated mTORC1 signaling
- Author(s)
  Akio Nakashima, Ayaka Momonami, Noriko Oshiro, Ushio Kikkawa
- Organizer
  第34回日本分子生物学会年会（BMSJ2011）(招待講演)
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] プロリン脱水素酵素（PRODH）は細胞老化誘導に関わる新規因子である
- Author(s)
  長野　太輝、山尾　俊介、中嶋　昭雄、吉川　潮、鎌田　真司
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜／パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] 分裂酵母TORC1とオートファジーの相互関係
- Author(s)
  中嶋昭雄、吉川潮
- Organizer
  第２回TOR研究会
- Place of Presentation
  神戸大学
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] 新規細胞老化誘導因子としてのDアミノ酸酸化酵素DAOの機能解析
- Author(s)
  山尾　俊介、長野　太輝、中嶋　昭雄、吉川　潮、鎌田　真司
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜／パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25640063
[Presentation] アミノ酸トランスポーターCat1のアレスチン様タンパク質による機能制御
- Author(s)
  中嶋昭雄、玉野井冬彦、吉川潮
- Organizer
  第４５回酵母遺伝学フォーラム研究報告会
- Place of Presentation
  京都大学宇治キャンパスおうばくプラザ
- Data Source
  KAKENHI-PROJECT-23770229
[Presentation] 新規細胞老化誘導因子としてのDアミノ酸酸化酵素DAOの機能解析
- Author(s)
  山尾　俊介、長野　太輝、中嶋　昭雄、吉川　潮、鎌田　真司
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26440053
[Presentation] アレスチン様タンパク質Art1によるアミノ酸トランスポーターCat1の機能制御
- Author(s)
  中嶋　昭雄、吉川潮、玉野井　冬彦
- Organizer
  酵母遺伝学フォーラム
- Place of Presentation
  九州大学医学部百年講堂
- Data Source
  KAKENHI-PROJECT-23770229

1. HARAYAMA HIROSHI (30281140)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KIKKAWA Ushio (40150354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. KAMADA Shinji (20243214)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 坂瀬充洋 (70463396)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OSHIRO Noriko (70372662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. FURUYASHIKI Tomoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. EGUCHI Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 鎌田振吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
9. 大坪瑶子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 長野太輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 江成政人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakashima Akio 中嶋 昭雄

中嶋 昭雄 ナカシマ アキオ

NAKASHIMA Akio 中嶋 昭雄

Research Projects

Research Products

Co-Researchers

Establishment and spread of the new assay for sperm flagellar function to improve artificial insemination results in the cattle

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減数分裂におけるTORC1キナーゼおよびオートファジーの機能制御の分子機構Principal Investigator

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Analyses of 3-dimensional rotation for the purpose of reconsidering criteria for the evaluation of flagellar functions in bull sperm

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Characterization and utilization of SPACA1 proteins for the purpose of establishment of a new method to predict freezability of bull sperm before cryopreservation

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Molecular mechanism of TORC1 activity and function in meiosis using a model organism.Principal Investigator

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Identification and characterization of cellular senescence-specific genes

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Molecular mechanism of the signaling involved in nutrient sensing and cell regulation that mediated by TORC1 in fission yeastPrincipal Investigator

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Regulation mechanisms of mTOR-mediated nutrient signaling by protein phosphatase PP2A

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[Journal Article] TORC1-Dependent Phosphorylation Targets in Fission Yeast2017

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[Journal Article] Proline dehydrogenase promotes senescence through the generation of reactive oxygen species.2017

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NAID

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[Journal Article] The loss of Lam2 and Npr2-Npr3 diminishes the vacuolar localization of Gtr1-Gtr2 and disinhibits TORC1 activity in fission yeast.2016

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[Journal Article] Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation.2016

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[Journal Article] Versatile function of the circadian protein CIPC as a regulator of Erk activation.2016

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Nakashima Akio 中嶋昭雄

中嶋昭雄ナカシマアキオ

NAKASHIMA Akio 中嶋昭雄