Tsutsumi Hiroshi 堤浩

… Alternative Names

TSUTSUMI Hiroshi 堤浩

堤浩

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Researcher Number	70398105
Other IDs
Affiliation (Current)	2025: 東京科学大学, 生命理工学院, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2023: 東京工業大学, 生命理工学院, 准教授 2015: 東京工業大学, 生命理工学研究科, 助教 2013: 東京工業大学, 大学院生命理工学研究科, 助教 2012: 東京工業大学, 生命理工学研究科, 助教 2008: 東京医科歯科大学, 生体材料工学の研究所, 助教 2007 – 2008: Tokyo Medical and Dental University, 生体材料工学研究所, 助教 2006: 東京医科歯科大学, 生体材料工学研究所, 科学技術振興研究員
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Science and Engineering / Chemical biology / Chemical pharmacy Except Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Biomolecular chemistry / Biofunction/Bioprocess / Drug development chemistry
Keywords	Principal Investigator ペプチド / イメージング / 自己集合 / pH / 三次元培養 / 細胞 / ヒドロゲル / 自己組織化 / 金属イオン / ナノ構造 … More / 遷移金属イオン / 蛍光プローブ / 生理活性 / 細胞培養 / 蛋白質 / 薬学 / スクリーニング / 可視化 / インターナリゼーション / 蛍光 / アンタゴニスト / CXCR4 … More Except Principal Investigator ペプチド / バイオチップ / タンパク質相互作用 / 薬剤複合体 / ファージ提示 / 細胞相互作用 / 生体分子科学 / 捕捉剤 / 慢性関節リウマチ / 関節リウマチ / 間節リウマチ / アンタゴニスト / T140 / FC131 / 関節リホマチ / アンタグニスト / HIV / 癌 / CXCR4 / ケモカイン Less

高機能化ペプチド材料を用いたがん細胞三次元培養と腫瘍微小環境の蛍光イメージングPrincipal Investigator
- Principal Investigator
  
  堤浩
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Tokyo Institute of Technology
水圏環境で自己集合化する金属イオン配位駆動型超分子ペプチドの開発と機能発現Principal Investigator
- Principal Investigator
  
  堤浩
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Construction of a Peptide Drug Discovery Platform Using Chemically Modified Peptide Phage Libraries
- Principal Investigator
  
  Mihara Hisakazu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Tokyo Institute of Technology
Development of functionalized peptide materials for 3D culture of cells and fluorescent imaging of extracellular environment.Principal Investigator
- Principal Investigator
  
  Tsutsumi Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Tokyo Institute of Technology
3D culture of cells and fluorescent imaging of extracellular environment using self-assembling peptide gelsPrincipal Investigator
- Principal Investigator
  
  Tsutsumi Hiroshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical biology
- Research Institution
  Tokyo Institute of Technology
Development of various functional peptides for biochips analyzing cancer cells
- Principal Investigator
  
  Mihara Hisakazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tokyo Institute of Technology
Construction of functional peptide ligands toward peptide biochips
- Principal Investigator
  
  MIHARA Hisakazu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Tokyo Institute of Technology
Development of the fluorescent bio-probes for the screening of antagonistsPrincipal Investigator
- Principal Investigator
  
  TSUTSUMI Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo Medical and Dental University
Medicinal chemistry based peptides against intractable disease including AIDS. Cancer and rheumatoid arthritis
- Principal Investigator
  
  TAMAMURA Hirokazu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University

All 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2008 2007 2006

All Journal Article Presentation Book Patent

[Book] 医療・診断をささえるペプチド科学－再生医療・DDS・診断への応用2017
- Author(s)
  堤浩、三原久和
- Total Pages
  315
- Publisher
  シーエムシー出版
- ISBN
  9784781312675
- Data Source
  KAKENHI-PROJECT-15H03113
[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術2017
- Author(s)
  堤浩、三原久和
- Total Pages
  557
- Publisher
  技術情報協会
- ISBN
  9784861046872
- Data Source
  KAKENHI-PROJECT-15H03113
[Book] バイオチップの基礎と応用－原理から最新の研究・開発動向まで－2015
- Author(s)
  臼井健二、堤　浩、三原久和
- Total Pages
  275
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-15H03113
[Journal Article] Selection of fluorescent biosensors against galectin-3 from an NBD-modified phage library displaying designed α-helical peptides2021
- Author(s)
  Hashimoto Masahiro、Miki Takayuki、Chang Iou Ven、Tsutsumi Hiroshi、Mihara Hisakazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 37 Pages: 127835-127835
- DOI
  10.1016/j.bmcl.2021.127835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15696, KAKENHI-PROJECT-19H02838
[Journal Article] hDM2 protein-binding peptides screened from stapled α-helical peptide phage display libraries with different types of staple linkers2020
- Author(s)
  Anananuchatkul Teerapat、Tsutsumi Hiroshi、Miki Takayuki、Mihara Hisakazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 23 Pages: 127605-127605
- DOI
  10.1016/j.bmcl.2020.127605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02838
[Journal Article] Short self‐assembling peptides with a urea bond: A new type of supramolecular peptide hydrogel materials2020
- Author(s)
  Tsutsumi Hiroshi、Tanaka Kunifumi、Chia Jyh Yea、Mihara Hisakazu
- Journal Title
  
  Peptide Science
  
  Volume: 113 Issue: 2 Pages: 1-13
- DOI
  10.1002/pep2.24214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05351
[Journal Article] Construction of a Stapled α-Helix Peptide Library Displayed on Phage for the Screening of Galectin-3-Binding Peptide Ligands2020
- Author(s)
  Anananuchatkul Teerapat、Chang Iou Ven、Miki Takayuki、Tsutsumi Hiroshi、Mihara Hisakazu
- Journal Title
  
  ACS Omega
  
  Volume: 5 Issue: 11 Pages: 5666-5674
- DOI
  10.1021/acsomega.9b03461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05351, KAKENHI-PROJECT-19K22249, KAKENHI-PROJECT-19K15696, KAKENHI-PROJECT-19H02838
[Journal Article] Self-Assembling Peptides as Building Blocks of Functional Materials for Biomedical Applications2019
- Author(s)
  Fukunaga Kazuto、Tsutsumi Hiroshi、Mihara Hisakazu
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 92 Issue: 2 Pages: 391-399
- DOI
  10.1246/bcsj.20180293
- NAID
  130007594392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05351
[Journal Article] Osteoblastic differentiation on hydrogels fabricated from Ca 2+ -responsive self-assembling peptides functionalized with bioactive peptides2018
- Author(s)
  Tsutsumi Hiroshi、Kawamura Megumi、Mihara Hisakazu
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 12 Pages: 3126-3132
- DOI
  10.1016/j.bmc.2018.04.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05351
[Journal Article] Gold Nanoparticles Conjugated with Glycopeptides for Lectin Detection and Imaging on Cell Surface2018
- Author(s)
  Hiroshi Tsutsumi, Tomoko Shirai, Hiroyuki Ohkusa, Hisakazu Mihara
- Journal Title
  
  Protein Peptide Letter
  
  Volume: 25 Issue: 1 Pages: 84-89
- DOI
  10.2174/0929866525666171218124434
- Data Source
  KAKENHI-PROJECT-15H03113
[Journal Article] Screening for Concanavalin A Binders from a Mannose-modified alpha-Helix Peptide Phage Library2017
- Author(s)
  Iou Ven Chang, Hiroshi Tsutsumi, Hisakazu Mihara
- Journal Title
  
  Molecular BioSystems
  
  Volume: 13 Issue: 11 Pages: 2222-2225
- DOI
  10.1039/c7mb00495h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03113
[Journal Article] Dihydrofolate Reductase Inhibitory Peptides Screened from a Structured Designed β-Loop Peptide Library Displayed on Phage2015
- Author(s)
  Hiroshi Tsutsumi, Kazuhiro Nakano, Hisakazu Mihara
- Journal Title
  
  Molecular BioSystems
  
  Volume: 11 Issue: 10 Pages: 2713-2716
- DOI
  10.1039/c5mb00316d
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H03113
[Journal Article] A Monosaccharide-modified Peptide Phage Library for Screening of Ligands to Carbohydrate-binding Proteins2013
- Author(s)
  K. Arai, H. Tsutsumi, H. Mihara
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 23 Pages: 4940-4943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] Gold Nanoparticles Conjugated with Monosaccharide-modified Peptide for Lectin Detection2012
- Author(s)
  H. Tsutsumi, H. Ohkusa, H. Park, T.Takahashi, H. Yuasa, H. Mihara
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 22 Pages: 6825-6827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22360341
[Journal Article] Fluorophore Labeling Enables Imaging and Evaluation of Specific CXCR4-Ligand Interaction at the Cell Membrane for Fluorescence-based Screening2008
- Author(s)
  Nomura W, Tanabe Y, Tsutsumi H, Tanaka T, Ohba K, Yamamoto N, Tamamura H
- Journal Title
  
  Bioconjugate Chem. 19
  
  Pages: 1917-1920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790010
[Journal Article] Fluorophore Labeling Enables Imaging and Evaluation of Specific CXCR4-Ligand Interaction at the Cell Membrane for Fluorescence-Based Screening2008
- Author(s)
  W. Nomura, Y. Tanabe, H. Tsutsumi, T. Tanaka, K. Ohba, N. Yamamoto, H. Tamamura(他0人、1番目)
- Journal Title
  
  Bioconjugate Chem 19巻
  
  Pages: 1917-1920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Fluorophore labeling enables imaging and evaluation of specific CXCR4-ligand interaction at the cell membrane for fluorescence-based screening2008
- Author(s)
  Nomura. W, Tanabe. Y, Tsutsumi. H, Tamamura. H, et.al.
- Journal Title
  
  Bioconjugate chemistry 19
  
  Pages: 1917-1920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790010
[Journal Article] Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists toward Downsizing2008
- Author(s)
  H. Tamamura, H. Tsutsumi, W. Nomura, N. Fujii(他0人、2番目)
- Journal Title
  
  Perspectives in Medicinal Chemistry 2巻
  
  Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Structure-activity Relationship Study of CXCR4 Antagonists Bearing the Cyclic Pentapeptide Scaffold : Identification of the New Pharmacophore2008
- Author(s)
  T. Tanaka, H. Tsutsumi, W. Nomura, N. Fujii, H. Tamamura(他10人、3番目)
- Journal Title
  
  Bioconjugate Chem 6(23)
  
  Pages: 4374-4377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] A Future Perspective on the Development of Chemokine Receptor CXCR4 Antagonists2008
- Author(s)
  H. Tamamura, H. Tsutsumi, W. Nomura, T. Tanaka , N. Fujii(他0人、2番目)
- Journal Title
  
  Expert Opin. Drug Discovery 3(10)巻
  
  Pages: 1155-1166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Inhibitors of the Chemokine Receptor CXCR4. Chemotherapy of AIDS, Metastatic Cancer Leukemia and Rheumatoid Arthritis2007
- Author(s)
  H. Tsutsumi, H. Tamamura, N. Fujii(他0人、1番目)
- Journal Title
  
  Lett. Drug Design Discovery 4巻
  
  Pages: 20-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] The Therapeutic Potential of the Chemokine Receptor CXCR4 Antagonists as Multi-functional Agents2007
- Author(s)
  H. Tsutsumi, H. Tamamura, N. Fujii(他7人、1番目)
- Journal Title
  
  Biopolymers : Peptide Science 88(2)巻
  
  Pages: 279-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Development of Low Molecular Weight CXCR4 Antagonists by Exploratory Structural Tuning of Cyclic Tetra- and Pentapeptide-scaffolds towards the Treatment of HIV Infection, Cancer Metastasis and Rheumatoid Arthritis2007
- Author(s)
  H. Tamamura, H. Tsutsumi, H. Masuno, N. Fujii(他0人、1番目)
- Journal Title
  
  Curr. Med. Chem 14(1)巻
  
  Pages: 93-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Versatile Use of Acid-catalyzed Ring-opening of β-Aziridinyl-a, 13-enoatesto Stereoselective Synthesis of Peptidomimetics2007
- Author(s)
  H. Tamamura, T. Tanaka, H. Tsutsumi, N. Fujii(他4人、3番目)
- Journal Title
  
  Tetrahedron 63巻
  
  Pages: 9243-9254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Identification of a New Class of Low Molecular Weight Antagonists against the Chemokine Receptor CXCR4 Having the Dipicolylamine-Zinc(II)Complex Structure2006
- Author(s)
  H. Tamamura, A. Ojida, H. Tsutsumi, H.Nakashima,N. Yamamoto, I. Hamachi, N. Fujii(他2人、1番目)
- Journal Title
  
  J Med.Chem 49巻
  
  Pages: 3412-3415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] he Chemokine Receptor CXCR4 as a Therapeutic Target for Several Diseases2006
- Author(s)
  H. Tamamura, H. Tsutsumi, N. Fujii(他0人、1番目)
- Journal Title
  
  Mini-Rev Med.Chem 6巻
  
  Pages: 989-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Development of a Linear Type of Low Molecular Weight CXCR4 Antagonists Based on T140 Analogs2006
- Author(s)
  H. Tamamura, H. Tsutsumi, H. Nakashima, N. Yamamoto, S. C. Peiper, N. Fujii(他5人、1番目)
- Journal Title
  
  Org.Biomol.Chem 4巻
  
  Pages: 2354-2357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Journal Article] Specific Probes for Chemokine Receptors2006
- Author(s)
  H. Tamamura, H. Tsutsumi(他0人、1番目)
- Journal Title
  
  Chem.Biol 13巻
  
  Pages: 8-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390035
[Patent] 標的物質の検出方法、並びに、これに用いるタグ、DNA、ベクター、プローブ及び検出キット2008
- Inventor(s)
  玉村啓和、堤浩
- Industrial Property Rights Holder
  国立大学法人東京医科歯科大学
- Filing Date
  2008-03-24
- Overseas
- Data Source
  KAKENHI-PROJECT-18390035
[Presentation] 1.がん細胞外pH環境のイメージングを指向し弱酸性環境応答的蛍光プローブを組み込んだ自己集合化ペプチドゲルの創製2021
- Author(s)
  青木　蓮・Chia Jyh Yea・三木　卓幸・三原　久和・堤　浩
- Organizer
  日本化学会　第１０１春季年会
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] 蛍光修飾αヘリックス設計ペプチドを提示したファージライブラリによるgalectin-3検出蛍光バイオセンサーの探索2021
- Author(s)
  橋本匡浩、三木卓幸、Iou Ven Chang、堤　浩、三原久和
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] 蛍光修飾ファージライブラリを用いたスクリーニングによるgalectin-3検出蛍光バイオセンサーの開発2021
- Author(s)
  橋本匡浩、三木卓幸、Chang Iou Ven、堤　浩、三原久和
- Organizer
  第31回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] 2.ウレア部位を有する金属イオン応答性自己集合化ペプチドの創製と金属ナノ材料への応用2021
- Author(s)
  塩田　隼平・三木　卓幸・三原　久和・堤　浩
- Organizer
  日本化学会　第１０１春季年会
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] ベンゼンスルホンアミド修飾環状ペプチドファージライブラリの構築2020
- Author(s)
  滝聞宏基, Anananuchatku Teerapat, 梶原圭悟, 三木卓幸, 三原久和, 堤浩
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] 修飾ファージライブラリによるGalectin-3応答蛍光バイオセンサーの探索2020
- Author(s)
  橋本匡浩, 三木卓幸, Iou Ven Chang, 堤浩, 三原久和
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] 自己集合化ペプチドマテリアル（2）：がん組織工学に向けた自己集合化ペプチドヒドロゲルを用いたがん細胞の三次元培養2019
- Author(s)
  堤　浩・Chia Jyh Yea・児玉伊織・三原久和
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] ウレア結合をもつ自己集合化ペプチドゲルを用いたがん細胞の三次元培養2019
- Author(s)
  堤　浩、Chia Jyh Yea、児玉伊織、三原久和
- Organizer
  第29回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] Development of fluorescent pH probes toward fluorescence imaging of extracellular environments using self-assembling peptides2019
- Author(s)
  Ren Aoki, Takayuki Miki, Hisakazu Mihara, Hiroshi Tsutsumi
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] 自己集合化ペプチドマテリアル（1）：ウレア結合をもつペプチドの構造-集合化能の相関解析と細胞培養材料応用2019
- Author(s)
  児玉伊織・Chia Jyh Yea・三原久和・堤　浩
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] Functionalized Supramolecular Peptide Hydrogels for 3D Culture of Cancer Cells2019
- Author(s)
  Hiroshi Tsutsumi
- Organizer
  10th RSC-CSJ Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] Self-assembling peptide materials functionalized with bioactive sequences for three dimensional MCF-7 cell culture2019
- Author(s)
  Jyh Yea Chia, Takayuki Miki, Hisakazu Mihara, Hiroshi Tsutsumi
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] Screening of peptide ligands for Galectin-3 using a designed stapled α-helix peptide phage library2019
- Author(s)
  Teerapat Anananuchatkul, Takayuki Miki, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  The 56th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-19H02838
[Presentation] Development of Self-Assembling Peptide Materials Recruiting Growth Factors via Heparin Binding2018
- Author(s)
  Hiroaki Oe, Hiroshi Tsutsumi, Takayuki Miki, Hisakazu Mihara
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] ウレア結合をもつ自己組織化ペプチドの生理活性配列導入による機能化とがん細胞培養2018
- Author(s)
  Chia Jyh Yea・児玉伊織・三原久和・堤　浩
- Organizer
  第12回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] Construction of supramolecular peptide hydrogels functionalized with bioactive sequences for 3D cell culture2018
- Author(s)
  Hiroshi Tsutsumi, Chia Jyh Yea, Iori Kodama, Hisakazu Mihara
- Organizer
  10th International Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] Functionalized self-assembling peptide materials with a urea bond towards the establishment of three dimensional cancer cell culture2018
- Author(s)
  Chia Jyh Yea・児玉伊織・三原久和・堤　浩
- Organizer
  第28回バイオ・高分子シンポジウム
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] Construction and Characterization of Functionalized Self-assembling Peptide Materials with a Urea Bond for Three Dimensional Cancer Cell Culture2018
- Author(s)
  Chia Jyh Yea, Iori Kodama, Takayuki Miki, Hisakazu Mihara, Hiroshi Tsutsumi
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05351
[Presentation] Monosaccharide-modified alpha-helix peptide phage libraries for carbohydrate-binding proteins2018
- Author(s)
  Iou Ven Chang, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 二次構造設計糖ペプチドファージライブラリの構築とレクチン結合性糖ペプチドリガンド探索への応用2017
- Author(s)
  堤浩、Chang IouVen、廣原庸平、三原久和
- Organizer
  日本化学会第97春季年会
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] Semisynthetic approach for ligand screening using chemically modified peptide phage libraries2017
- Author(s)
  Hiroshi Tsutsumi, Iou Ven Chang, Teerapat Anananuchatkul, Hisakazu Mihara
- Organizer
  第54回ペプチド討論会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 両親媒性αヘリックスペプチドの細胞導入特性の解析2017
- Author(s)
  澁谷圭祐、陶欣然、堤浩、三原久和
- Organizer
  日本化学会第97春季年会
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 単糖導入ペプチド修飾金ナノ粒子の合成とレクチンタンパク質との相互作用2016
- Author(s)
  白井智子、堤　浩、湯浅英哉、三原久和
- Organizer
  日本化学会第96春季年会
- Place of Presentation
  京都
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 2.Construction of pH-responsive hydrogel materials fabricated from designed self-assembing peptides for cell culture2016
- Author(s)
  Hiroshi Tsutsumi・Hisakazu Mihara
- Organizer
  International Conference on Single Cell Research 2016
- Place of Presentation
  東京
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K16559
[Presentation] 細胞識別に向けた種々の両親媒性α-ヘリックスペプチドの細胞膜透過活性解析2016
- Author(s)
  堤浩、陶欣然、三原久和
- Organizer
  第10回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 1.生理活性配列導入による自己組織化ペプチドゲルの機能化と骨芽細胞培養への応用2016
- Author(s)
  堤　浩・川村　愛・三原久和
- Organizer
  第10回バイオ関連化学シンポジウム
- Place of Presentation
  金沢
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15K16559
[Presentation] Screening for concanavalin A binders from a mannose-conjugated alpha-helix peptide phage library2016
- Author(s)
  IouVen Chang, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  第53回ペプチド討論会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 1.機能性配列を導入した自己組織化ペプチドゲルの創製と骨芽細胞培養への応用2016
- Author(s)
  堤　浩・川村　愛・福永和人・三原久和
- Organizer
  第65回高分子討論会
- Place of Presentation
  神奈川
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-15K16559
[Presentation] Construction and application of pH-responsive hydrogel materials fabricated from designed self-assembling peptides2015
- Author(s)
  Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  神奈川
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-15K16559
[Presentation] 自己組織化ペプチドのpH応答的ゲル形成と細胞培養への応用2015
- Author(s)
  堤　浩、福永和人、三原久和
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15K16559
[Presentation] A mannose-conjugated α-helix designed peptide phage-library as a tool for the screening of Concanavalin A binding ligands2015
- Author(s)
  IouVen Chang、Yohei Hirohara、Hiroshi Tsutsumi、Hisakazu Mihara
- Organizer
  The 7th International Peptide Symposium
- Place of Presentation
  Singapore
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] 単糖修飾β-ループペプチドファージライブラリの構築と糖結合タンパク質結合性ペプチドの探索2015
- Author(s)
  廣原庸平、新井佳菜子、堤　浩、三原久和
- Organizer
  第25回バイオ・高分子シンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] ナノファイバーを形成する自己組織化ペプチドの創製と細胞培養への応用2015
- Author(s)
  堤　浩、福永和人、三原久和
- Organizer
  平成27年度繊維学会年次大会
- Place of Presentation
  東京
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15K16559
[Presentation] 細胞選択的な膜透過性を有する設計α-ヘリックスペプチドの機能解析2015
- Author(s)
  堤　浩、陶欣然、三原久和
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15H03113
[Presentation] pH応答性自己組織化ペプチドゲルの創製と細胞培養材料への応用2015
- Author(s)
  堤　浩、田中邦史、三原久和
- Organizer
  第65回高分子討論会
- Place of Presentation
  仙台
- Year and Date
  2015-09-14
- Data Source
  KAKENHI-PROJECT-15K16559
[Presentation] CONSTRUCTION OF A PHAGE LIBRARY DISPLAYING MANNOSE-MODIFIED PEPTIDES AND SCREENING OF BINDING PEPTIDES TO CONCANAVALIN A2012
- Author(s)
  Kanako Arai, Hiromichi Okura, Hiroshi Tsutsumi, Hisakazu Mihara
- Organizer
  第49回日本ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] マンノース修飾ペプチドを提示したファージライブラリの構築とコンカナバリンA結合性ペプチドの探索2012
- Author(s)
  新井佳菜子,大倉裕通,堤浩,三原久和
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] αへリックスペプチドを結合した金ナノ粒子の細胞導入活性とガン細胞応用2011
- Author(s)
  Park Hyejin,高橋剛,堤浩,三原久和
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] レクチンに対する結合多様性を有する単糖導入ペプチド修飾金ナノ粒子の創製2011
- Author(s)
  大草寛之,朴恵珍,高橋剛,堤浩,湯浅英哉,三原久和
- Organizer
  第5回バイオ関連化学シンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-22360341
[Presentation] 蛍光性アンタゴニストを用いたCXCR4のイメージングと阻害剤のスクリーニング法の確立2008
- Author(s)
  田部泰章・野村渉・堤浩・田中智博・大庭賢二・駒野淳・山本直樹・藤井信孝・玉村啓和
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  立教大学
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19790010

1. MIHARA Hisakazu (30183966)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
2. TAMAMURA Hirokazu (80217182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
3. 増野弘幸 (80376714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 三木卓幸 (20823991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

Tsutsumi Hiroshi 堤 浩

TSUTSUMI Hiroshi 堤 浩

堤浩

Research Projects

Research Products

Co-Researchers

高機能化ペプチド材料を用いたがん細胞三次元培養と腫瘍微小環境の蛍光イメージングPrincipal Investigator

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水圏環境で自己集合化する金属イオン配位駆動型超分子ペプチドの開発と機能発現Principal Investigator

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Construction of a Peptide Drug Discovery Platform Using Chemically Modified Peptide Phage Libraries

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Development of functionalized peptide materials for 3D culture of cells and fluorescent imaging of extracellular environment.Principal Investigator

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3D culture of cells and fluorescent imaging of extracellular environment using self-assembling peptide gelsPrincipal Investigator

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Development of various functional peptides for biochips analyzing cancer cells

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Construction of functional peptide ligands toward peptide biochips

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Development of the fluorescent bio-probes for the screening of antagonistsPrincipal Investigator

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Medicinal chemistry based peptides against intractable disease including AIDS. Cancer and rheumatoid arthritis

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[Book] 医療・診断をささえるペプチド科学－再生医療・DDS・診断への応用2017

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[Book] ペプチド医薬品のスクリーニング・安定化・製剤化技術2017

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[Book] バイオチップの基礎と応用－原理から最新の研究・開発動向まで－2015

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[Journal Article] Selection of fluorescent biosensors against galectin-3 from an NBD-modified phage library displaying designed α-helical peptides2021

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Tsutsumi Hiroshi 堤浩

TSUTSUMI Hiroshi 堤浩