KOGURE Takayuki 小暮高之

Researcher Number	70400330
Other IDs
Affiliation (Current)	2025: 東北医科薬科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 東北医科薬科大学, 医学部, 准教授 2019 – 2021: 東北医科薬科大学, 医学部, 講師 2017 – 2018: 東北大学, 医学系研究科, 非常勤講師 2017: 東北大学, 大学病院, 非常勤講師 2017: 東北医科薬科大学, 大学病院, 講師 … More 2013 – 2016: 東北大学, 大学病院, 助教 2015: 東北大学, 病院, 助教 2007 – 2008: Tohoku University, 病院, 医員 2006: TOHOKU UNIVERSITY, HOSPITAL, Senior Residents, 病院・医員 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 肝細胞癌 / エキソソーム / 癌幹細胞 / チロシンキナーゼ阻害薬 / 微小環境 / microRNA / 耐性 / 機能性RNA / 肝臓病学 Except Principal Investigator 非アルコール性脂肪性肝炎 … More / 細胞外小胞 / 膵癌 / アミノ酸 / NAFLD / 非アルコール性脂肪性肝疾患 / 遊離アミノ酸 / 門脈血 / 肝細胞癌 / エクソソーム / 長鎖ノンコーディングRNA / リキッドバイオプシー / lncRNA / ncRNA / 酸化ストレス / VLDL / NASH / バイオマーカー / 上皮間葉形質転換(EMT) / 細胞外小胞(EV) / EMT / liquid biopsy / extracellular vesicles / long non-coding RNA / 上皮間葉形質転換 / 体液診断 / 長鎖機能性RNA / 門脈 / 小胞体ストレス / オレイン酸 / パルミチン酸 / 肝細胞 / 潅流培養 / 3D培養 / 脂肪肝 / liver cirrhosis / hapatocellular carcinoma / liver failure / natal immunity / branched chain amino acid / dendritic cell / 分岐鎖アミノ酸 / 肝硬変 / 肝不全 / 自然免疫 / 分枝鎖アミノ酸 / 樹状細胞 / メタボローム解析 / PS-L1 / 免疫抑制細胞 / 免疫細胞 / HCV / HBV / Tregs / PD-L1 / MDSCs / HCC Less

The clinical applications of long non-coding RNA and extracellular vesicles to diagnosis and therapy for pancreatic cancer
- Principal Investigator
  
  TAKAHASHI Kenji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
肝癌のチロシンキナーゼ阻害薬に対する耐性獲得機序の解明と耐性克服薬の探索Principal Investigator
- Principal Investigator
  
  小暮高之
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Impact of free amino acids on intracellular stress response mechanisms in hepatic steatosis.
- Principal Investigator
  
  Kakazu Eiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Analysis of the mechanism of tumor microenvironment modulation through exosomes in hepatocellular cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  Kogure Takayuki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Tohoku University
Analysis of EV encapsulated long non-coding RNA as the liquid biopsy for pancreatic cancer
- Principal Investigator
  
  TAKAHASHI KENJI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
Elucidation of the association between non alcoholic steatohepatitis and endoplasmic reticulum stress by metabolomics of portal blood
- Principal Investigator
  
  KAKAZU EIJI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Development of HCC treatment by analyzing the induction of MDSC, TAM and Tregs
- Principal Investigator
  
  Kondo Yasuteru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Exosomal transfer of functional RNA in hepatocellular carcinoma cell proliferationPrincipal Investigator
- Principal Investigator
  
  Kogure Takayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
amino acids metabolism and immune abnormality in non alcoholic steatohepatitis
- Principal Investigator
  
  KAKAZU Eiji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Liver Cancer stem cells and chemotherapeutic resistancePrincipal Investigator
- Principal Investigator
  
  KOGURE Takayuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Extracellular Branched-chain Amino Acids, Especially Valine, Regulate Maturation and Function of Monocyte-derived Dendritic Cells
- Principal Investigator
  
  UENO Yoshiyuki, 菅野記豊
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  TOHOKU UNIVERSITY

All 2023 2021 2018 2017 2016 2015 2014 2013 2009 2008 2006 Other

All Journal Article Presentation

[Journal Article] The profiling of plasma free amino acids and the relationship between serum albumin and plasma-branched chain amino acids in chronic liver disease: a single-center retrospective study.2018
- Author(s)
  Akitoshi Sano, Eiji Kakazu, Tatsuki Morosawa, Jun Inoue, Takayuki Kogure, Masashi Ninomiya, Tomoaki Iwata, Teruyuki Umetsu, Takuya Nakamura, Satoshi Takai, Tooru Shimosegawa
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中 Issue: 8 Pages: 978-988
- DOI
  10.1007/s00535-018-1435-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09336
[Journal Article] Shifting hepatitis B virus genotypes of acute hepatitis B patients in northeast Japan2016
- Author(s)
  Inoue J, Kondo Y, Umetsu T, Yamamoto T, Miura M, Mano Y, Kobayashi T, Obara N, Niitsuma H, Kogure T, Nakagome Y, Kimura O, Iwata T, Morosawa T, Fujisaka Y, Shimosegawa T
- Journal Title
  
  J Med Virol
  
  Volume: 88 Issue: 1 Pages: 69-78
- DOI
  10.1002/jmv.24309
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08981, KAKENHI-PROJECT-25460970
[Journal Article] Differential expression of CX3CL1 in HBV-replicating hepatoma cells could affect the migration-activity of CX3CR1+ immune cells2015
- Author(s)
  Kondo Y, Kimura O, Tanaka Y, Ninomiya M, Kogure T, Inoue J, Sugiyama M, Iwata T, Morosawa T, Fujisaka Y, Shimosegawa T
- Journal Title
  
  J Virol.
  
  Volume: Jul 15;89(14) Issue: 14 Pages: 7016-27
- DOI
  10.1128/jvi.00716-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460970
[Journal Article] Radiation Therapy Is a Reasonable Option for Improving the Prognosis in Hepatocellular Carcinoma2015
- Author(s)
  Kondo Y, Kimura O, Kogure T, Ninomiya M, Umezawa R, Sugawara T, Matsushita H, Jingu K, Nakagome Y, Iwta T, Morsawa T, Fujisaka Y, Iwasaki T, Shimosegawa T
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 237 Issue: 4 Pages: 249-257
- DOI
  10.1620/tjem.237.249
- NAID
  130005108584
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460970
[Journal Article] Shimosegawa T . Sequential analysis of amino acid substitutions with hepatitis B virus in association with nucleoside/nucleotide analog treatment detected by deep sequencing2014
- Author(s)
  Ninomiya M, Kondo Y, Niihori T, Nagashima T, Kogure T, Kakazu E, Kimura O, Aoki Y, Matsubara Y
- Journal Title
  
  Hepatol Res
  
  Volume: 44(6) Issue: 6 Pages: 678-684
- DOI
  10.1111/hepr.12168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390268, KAKENHI-PROJECT-23791148, KAKENHI-PROJECT-25460970
[Journal Article] Involvement of microRNA-29a in epigenetic regulation of transforming growth factor-β-induced epithelial-mesenchymal transition in hepatocellular carcinoma2014
- Author(s)
  Kogure T, Kondo Y, Kakazu E, Ninomiya M, Kimura O, Shimosegawa T.
- Journal Title
  
  Hepatol Res.
  
  Volume: 2014 Issue: 8 Pages: 907-919
- DOI
  10.1111/hepr.12188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460970
[Journal Article] Expression of EpCAM Increases in the Hepatitis B Related and the Treatment-Resistant Hepatocellular Carcinoma.2014
- Author(s)
  Kimura O, Kondo Y, Kogure T, Kakazu E, Ninomiya M, Iwata T, Morosawa T, Shimosegawa T.
- Journal Title
  
  BioMed Research International
  
  Volume: 2014 Pages: 172913-172913
- DOI
  10.1155/2014/172913
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460970
[Journal Article] Distinct MicroRNAs Expression Profile in Primary Biliary Cirrhosis and Evaluation of miR 505-3p and miR197-3p as Novel Biomarkers2013
- Author(s)
  Ninomiya, M., Kondo, Y., Funayama, R., Nagashima, T., Kogure, T., Kakazu, E., Kimura, O., Ueno, Y., Nakayama, K., Shimosegawa, T.
- Journal Title
  
  PloS one
  
  Volume: 8 Issue: 6 Pages: e66086-e66086
- DOI
  10.1371/journal.pone.0066086
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24116503, KAKENHI-PROJECT-24700951, KAKENHI-PROJECT-25460970
[Journal Article] Supplementation of branched-chain amino acids maintains the serum albumin level in the course of hepatocellular carcinoma recurrence.2013
- Author(s)
  Kakazu E, Kondo Y, Kogure T, Ninomiya M, Kimura O, Iwata T, Morosawa T, Iwasaki T, Shimosegawa T.
- Journal Title
  
  The Tohoku Journal of Experimental Medicine
  
  Volume: 230 Pages: 191-196
- NAID
  10031194081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460972
[Journal Article] An imbalance of plasma amino acids in patients with cirrhosis disturbs the tricarboxylic acid cycle of dendritic cell.2013
- Author(s)
  Kakazu E, Kondo Y, Kogure T, Ninomoiya M, Kimura O, Shimosegawa T
- Journal Title
  
  Sci Rep.
  
  Volume: 2013 Dec 10;3:3459. Issue: 1 Pages: 3459-3459
- DOI
  10.1038/srep03459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460970, KAKENHI-PROJECT-25460972
[Journal Article] The effect of branched chain amino acid formulation on keeping the serum albumin level in the course of hepatocellular carcinoma recurrence.2013
- Author(s)
  Kakazu E, Kondo Y, Kogure T, Ninomiya M, Kimura O, Iwata T, Morosawa T, Iwasaki T, Shimosegawa T.
- Journal Title
  
  Tohoku J Exp Med.
  
  Volume: 230(4) Pages: 191-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460970
[Journal Article] A novel third generation bisphosphonate, minodronate(Y M529), prevented proliferation and migration of hepatoc ellular carcinoma cells through inhibition of mevalonate pathway2009
- Author(s)
  小暮高之
- Journal Title
  
  Hepatol Research 39
  
  Pages: 479-489
- NAID
  10025325887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790466
[Journal Article] Sustained viral response of a case of acute hepatitis C virus infection via needle-stick injury.2006
- Author(s)
  Kogure T, et al.
- Journal Title
  
  World J Gastroenterol 12
  
  Pages: 4757-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590609
[Journal Article] Sustained viral response of a case of acute hepatitis C virus infection via needle-stick injury.2006
- Author(s)
  Kogure T, Ueno Y, et al.
- Journal Title
  
  World J Gastroenterol 12
  
  Pages: 4757-4760
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590609
[Journal Article] A novel third generation bisphosphonate, minodronate (YM529), prevented proliferation and migration of hepatocellular carcinoma cells through inhibition of mevalonate pathway.
- Author(s)
  小暮高之、上野義之、木村修、他5名
- Journal Title
  
  Hepatology Research 2009 (印刷中)
- NAID
  10025325887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790466
[Presentation] MicroRNA-1297 is involved in the resistance of lenvatinib in hepatocellular carcinoma2023
- Author(s)
  Takayuki Kogure, Mari Satoh, Takehito Ito, Kennichi Satoh
- Organizer
  The Liver Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08293
[Presentation] microRNA-1297は低酸素下に誘導される肝細胞癌のlenvatinib耐性に関与する2023
- Author(s)
  小暮高之、佐藤麻理、伊藤豪仁、遠藤克哉、廣田衛久、佐藤賢一
- Organizer
  第109回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K08293
[Presentation] Identification of microRNAs involved in resistance of lenvatinib under hypoxia in hepatocellular carcinoma2023
- Author(s)
  Mari Satoh, Takayuki Kogure, Takehito Ito, Masanori Takahashi, Kouji Okada, Kensuke Usui, Kennichi Satoh
- Organizer
  The Liver Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08293
[Presentation] MicroRNA-491-5p is involved in the resistance to lenvatinib induced under hypoxia in hepatocellular carcinoma2021
- Author(s)
  Mari Satoh, Takayuki Kogure, Masanori Takahashi, Kouji Okada, Kennichi Satoh
- Organizer
  The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09401
[Presentation] 門脈血類似・三次元潅流培養による肝細胞に対する脂肪毒性と小胞体ストレスの評価2017
- Author(s)
  嘉数英二、佐野晃俊、井上　淳、小暮高之、二宮匡史、諸沢　樹、梅津輝行、高井　智、中村琢也、岩田朋晃、下瀬川徹
- Organizer
  肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16K09336
[Presentation] The relationship between the plasma free amino acids and the pathological features in nonalcoholic fatty liver disease (NAFLD).2017
- Author(s)
  Eiji Kakazu, Akitoshi Sano, Tatsuki Morosawa, Jun Inoue, Takayuki Kogure, Masashi Ninomiya, Tomoaki Iwata, Teruyuki Umetsu, Takuya Nakamura, Satoshi Takai, Tooru Shimosegawa
- Organizer
  アメリカ肝臓学会 annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09336
[Presentation] 肝細胞癌における細胞間コミュニケーションの新規機序細胞外分泌顆粒を介したlong non-coding RNAの細胞間輸送2016
- Author(s)
  小暮貴之
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ幕張　千葉
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-25460971
[Presentation] Profiling of hepatic portal blood metabolites in Non-alcoholic fatty liver disease mice by capillary electrophoresis time-of-flight mass spectrometry (CE-TOFMS)2016
- Author(s)
  Eiji Kakazu, Harmeet Malhi, Jun Inoue, Masashi Ninomiya, Takayuki Kogure, Tooru Shimosegawa
- Organizer
  Asian Pacific Digestive Week
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2016-10-04
- Data Source
  KAKENHI-PROJECT-16K09336
[Presentation] The evaluation of endoplasmic reticulum (ER) stress in hepatocytes under a new 3D perfusion culture system consistent with hepatic portal blood.2016
- Author(s)
  Eiji Kakazu, Jun Inoue, Takayuki Kogure, Masashi Ninomiya, Tatsuki Morosawa, Teruyuki Umetsu, Takuya Nakamura, Satoshi Takai, Tooru Shimosegawa
- Organizer
  American Association for the Study of Liver Diseases
- Place of Presentation
  John B. Hynes Veterans Memorial Convention Center（ボストン　米国）
- Year and Date
  2016-11-13
- Data Source
  KAKENHI-PROJECT-16K09336
[Presentation] アンチセンスオリゴヌクレオチドを用いたmiR-221発現抑制による肝癌増殖制御　同所移植マウス肝癌モデルを用いたin vivo研究2013
- Author(s)
  小暮高之, 近藤泰輝, 嘉数英二, 二宮匡史, 木村修, 岩田朋晃, 諸沢樹, 岩崎隆雄, 下瀬川徹
- Organizer
  日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] 肝硬変に出現する血漿アミノ酸不均衡が樹状細胞機能を抑制するメカニズム2013
- Author(s)
  嘉数英二、　諸沢　樹、　近藤泰輝、　小暮高之、　二宮匡史、　木村　修、　岩田朋晃、　下瀬川徹
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460972
[Presentation] An appropriate amount of Sorafenib could suppress the myeloid derived suppressor cells (MDSC) and Tregs in HCC patients2013
- Author(s)
  Kondo Y, Iwata T, Kimura O, Ninomiya M, Morosawa T, Kakazu E, Kogure T, Shimosegawa T
- Organizer
  AASLD Annual Meeting
- Place of Presentation
  ワシントン　D.C.　アメリカ合衆国
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] An imbalance in plasma amino acids of advanced cirrhotic patients suppresses dendritic cells maturation by disturbing the mitochondrial TCA cycle.2013
- Author(s)
  Eiji Kakazu, Yasuteru Kondo, Takayuki Kogure, Masashi Ninomiya, Osamu Kimura, Tatsuki Morosawa, Tomoaki Iwata, Yoshiyuki Ueno, Tooru Shimosegawa
- Organizer
  Asian Pacific Association for The Study of the Liver
- Place of Presentation
  Suntec City, Singapore
- Data Source
  KAKENHI-PROJECT-25460972
[Presentation] 肝細胞癌に誘導されたMyeloid-Derived Suppressor Cells(MDSCs)とPD-L1発現の関係2013
- Author(s)
  岩田朋晃, 近藤泰輝, 木村修, 二宮匡史, 小暮高之, 嘉数英二, 諸沢樹, 下瀬川徹
- Organizer
  日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] The tricarboxylic acid (TCA) cycle of dendritic cells was disturbed by imbalance of plasma amino acid observed in cirrhosis.2013
- Author(s)
  Eiji Kakazu, Yasuteru Kondo, Takayuki Kogure, Masashi Ninomiya, Osamu Kimura, Tatsuki Morosawa, Tomoaki Iwata, Yoshiyuki Ueno, Tooru Shimosegawa
- Organizer
  The American Association for the Study of Liver Diseases
- Place of Presentation
  Washington dc, USA
- Data Source
  KAKENHI-PROJECT-25460972
[Presentation] 肝細胞癌におけるABCG2の発現とcancer stem cellの可能性2009
- Author(s)
  木村修、小暮高之、上野義之
- Organizer
  第44回日本肝臓学会
- Place of Presentation
  松山
- Year and Date
  2009-06-05
- Data Source
  KAKENHI-PROJECT-19790466
[Presentation] The Expression of ABCG2 in the Hepatocellular Carcinoma and the Possibility of the Cancer Stem Cell2009
- Author(s)
  木村修、小暮高之、上野義之
- Organizer
  第19回アジア太平洋肝臓学会議
- Place of Presentation
  香港
- Year and Date
  2009-02-15
- Data Source
  KAKENHI-PROJECT-19790466
[Presentation] 肝細胞癌におけるABCG2の発現とcancer stem cellの可能性2009
- Author(s)
  小暮高之、木村修、上野義之
- Organizer
  第16回消化器関連学会週間シンポジウム7 Hepatic stem cellとCancer stem cell
- Place of Presentation
  東京
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19790466
[Presentation] シンポジウム7Hepatic stem cellとCancer stem cell肝細胞癌におけるABCG2の発現とcancer stem cellの可能性2008
- Author(s)
  小暮高之
- Organizer
  第16回消化器関連学会週間
- Place of Presentation
  東京
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-19790466
[Presentation] Down regulation of hsa-miR146b-5p might affect the immunopathogenesis of chronic hepatitis C patients
- Author(s)
  Yasuteru Kondo, Masashi Ninomiya, Osamu Kimura, Takayuki Kogure, Yasuhito Tanaka, Yu Nakagome, Tomoaki Iwata, Tatsuki Morosawa, Yasuyuki Fujisaka, Tomoo Kobayashi, Tooru Shimosegawa
- Organizer
  AASLD2014 Annual Meeting
- Place of Presentation
  ボストン、米国
- Year and Date
  2014-11-07 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] HBcAg-specific IL10 production might be an important predictor for the responsiveness to Entercavir-Interferon sequential therapy in chronic hepatitis B patients
- Author(s)
  Yasuteru Kondo, Osamu Kimura, Tomoaki Iwata, Tomoo Kobayashi, Yu Nakagome, Tatsuki Morosawa, Takayuki Kogure, Jun Inoue, Yasuhito Tanaka, Tooru Shimosegawa
- Organizer
  HBV International Meeting on Molecular Biology of Hepatitis B Viruses
- Place of Presentation
  ロサンゼルス、米国
- Year and Date
  2014-09-03 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] 高度線維化症例におけるVitamin D補充の意義
- Author(s)
  近藤泰輝、木村修、中込悠、小暮高之、岩田朋晃、諸沢樹、藤坂泰之、小林光樹、佐藤修一、木田真美、小林智夫、宮崎豊、城戸治、小原範之、三浦雅人、涌井裕太、五十嵐勇彦、下瀬川徹
- Organizer
  JDDW2014
- Place of Presentation
  神戸市
- Year and Date
  2014-10-24 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] 進行肝細胞癌患者におけるソラフェニブ血中濃度と免疫病態解析
- Author(s)
  近藤泰輝、岩田朋晃、木村修、諸沢樹、藤坂泰之、島田美樹、小暮高之、二宮匡史、下瀬川徹
- Organizer
  第100回　日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-23 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] Hepatoma with HBV replication could attract CX3CR1+ NKG2Dlow NK cells and CX3CR1+PD-1+ CD8+ T cells
- Author(s)
  Yasuteru Kondo, Osamu Kimura, Tomoaki Iwata, Tatsuki Morosawa, Masashi Ninomiya, Eiji Kakazu, Takayuki Kogure, Yasuhito Tanaka, Tooru Shimosegawa
- Organizer
  DDW
- Place of Presentation
  シカゴ、米国
- Year and Date
  2014-05-03 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] CX3CL1-CX3CR1 axisはB型肝炎、肝癌の免疫病態に影響を与える
- Author(s)
  近藤泰輝、木村修、岩田朋晃、二宮匡史、諸沢樹、小暮高之、藤坂泰之、新妻宏文、中込悠、下瀬川徹
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] B型肝炎の進展、発癌、ETV-IFN Sequential療法効果に影響を与える因子の同定
- Author(s)
  近藤泰輝、木村修、中込悠、新妻宏文、二宮匡史、小暮高之、岩田朋晃、諸沢樹、藤坂泰之、渡辺大亮、小林智夫、下瀬川徹
- Organizer
  JDDW2014
- Place of Presentation
  神戸市
- Year and Date
  2014-10-23 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] The frequency of HBV-specific IL10 production and MDSCs might predict the responsiveness of Entercavir-Interferon sequential therapy in chronic hepatitis B patients
- Author(s)
  Yasuteru Kondo, Osamu Kimura, Tomoaki Iwata, Tatsuki Morosawa, Yasuyuki Fujisaka, Takayuki Kogure,Yu Nakagome,Tooru Shimosegawa
- Organizer
  The 11Th JSH Single Topic Conference
- Place of Presentation
  広島市
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25460970
[Presentation] PD-L1+ MDSCs are likely to become a new biomarker in hepatocellular carcinoma patients
- Author(s)
  Tomoaki Iwata、Yasuteru Kondo、Osamu Kimura, Takayuki Kogure, Tatsuki Morosawa, Yasuyuki Fujisaka, Tooru Shimosegawa
- Organizer
  AASLD2014 Annual Meeting
- Place of Presentation
  ボストン、米国
- Year and Date
  2014-11-07 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25460970

1. KAKAZU Eiji (20509377)

# of Collaborated Projects: 7 results

# of Collaborated Products: 17 results
2. TAKAHASHI KENJI (00736332)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. Kondo Yasuteru (70455822)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
4. UENO Yoshiyuki (70282126)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. FUKUSHIMA Koji (20400476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 菅野記豊 (70375004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐藤麻理 (20846018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 濱田晋 (20451560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 岩田朋晃 (30803647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 井上淳 (60455821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 二宮匡史 (70583938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 水上裕輔 (30400089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小野裕介 (40742648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藤井聡 (90291228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 谷上賢瑞 (90648627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KIMURA Osamu

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. NIIHORI Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 長嶋剛史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 松原洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOGURE Takayuki 小暮 高之

Research Projects

Research Products

Co-Researchers

The clinical applications of long non-coding RNA and extracellular vesicles to diagnosis and therapy for pancreatic cancer

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肝癌のチロシンキナーゼ阻害薬に対する耐性獲得機序の解明と耐性克服薬の探索Principal Investigator

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Impact of free amino acids on intracellular stress response mechanisms in hepatic steatosis.

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Analysis of the mechanism of tumor microenvironment modulation through exosomes in hepatocellular cancer stem cellsPrincipal Investigator

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Analysis of EV encapsulated long non-coding RNA as the liquid biopsy for pancreatic cancer

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Elucidation of the association between non alcoholic steatohepatitis and endoplasmic reticulum stress by metabolomics of portal blood

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Development of HCC treatment by analyzing the induction of MDSC, TAM and Tregs

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Exosomal transfer of functional RNA in hepatocellular carcinoma cell proliferationPrincipal Investigator

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amino acids metabolism and immune abnormality in non alcoholic steatohepatitis

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Liver Cancer stem cells and chemotherapeutic resistancePrincipal Investigator

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Extracellular Branched-chain Amino Acids, Especially Valine, Regulate Maturation and Function of Monocyte-derived Dendritic Cells

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[Journal Article] The profiling of plasma free amino acids and the relationship between serum albumin and plasma-branched chain amino acids in chronic liver disease: a single-center retrospective study.2018

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[Journal Article] Shifting hepatitis B virus genotypes of acute hepatitis B patients in northeast Japan2016

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KOGURE Takayuki 小暮高之