Koshiba Takumi 小柴琢己

… Alternative Names

KOSHIBA TAKUMI 小柴琢己

KOSHIBA Takumi 小柴琢己

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Researcher Number	70403970
Other IDs	https://orcid.org/0000-0001-8535-5043
Affiliation (Current)	2025: 福岡大学, 理学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 福岡大学, 理学部, 教授 2016 – 2018: 九州大学, 理学研究院, 准教授 2012 – 2016: 九州大学, 理学(系)研究科(研究院), 准教授 2007 – 2009: 九州大学, 理学研究院, 准教授 2008: Kyushu University, 大学院・理学研究院, 准教授 2007: Kyushu University, 理学研究所, 准教授 2005 – 2006: Kyushu University, Faculty of Sciences, Associate Professor, 大学院理学研究院, 助教授
Review Section/Research Field	Principal Investigator Biophysics / Biological Sciences / Transformative Research Areas, Section (III) / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Pathology, Infection/Immunology, and related fields / Bio-related chemistry / Structural biochemistry Except Principal Investigator Biological Sciences / Structural biochemistry
Keywords	Principal Investigator ミトコンドリア / 自然免疫 / 抗ウイルス自然免疫 / MAVS / 抗ウイルス免疫 / シグナル伝達 / RNAウイルス / ストレス応答 / 感染微生物 / 感染症 … More / トキソプラズマ原虫 / 分子基盤解析 / ダイナミクス / 細胞内シグナル伝達 / ストレス / 新規分子探索 / 細胞生物学 / プロテオーム解析 / 細胞内寄生虫 / イムノコンドリア / miRNA / 相互作用解析 / CLPB / PHB2 / X線結晶構造解析 / プロヒビチン / 高次機能 / ウイルス / 改変 / 構造特性 / タンパク質 / 形態形成 / 構造改変 / ウイルスタンパク質 / メタロプロテアーゼ / GTPase / 酵素活性 / 酵素機能 / 形態調節 / 分子機構 / A型インフルエンザウイルス / ウイルス感染 / PB1-F2 / A型インフルエンザ / 分子間相互作用 / BRET / 分子間相互作用解析 / 蛋白質科学 / インターフェロンβ / Mitofusin 2 / インターフェロン / 血球細胞 / グラム陰性菌 / 生体防御機構 / Factor C / リポ多糖認識蛋白質 … More Except Principal Investigator 分子認識 / 生体防御 / パターン認識 / 非自己認識 / 自然免疫 / Pattern recognition / Molecular recognition / Self defense / Non-self recognition / Innate immunity / 異物認識 / キチン結合蛋白質 / ヘモシアニン / 抗菌蛋白質 / NMR / シグナル伝達 / プロテアーゼ / 補体レクチン経路 / Gタンパク質 / カブトガニ / LPS / リポ多糖 / パターン / β-1,3-グルカン Less

感染微生物による宿主ミトコンドリアのマニピュレーションPrincipal Investigator
- Principal Investigator
  
  小柴琢己
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Fukuoka University
Molecular basis of mitochondrial dynamics and their contribution to cellular stress responsesPrincipal Investigator
- Principal Investigator
  
  小柴琢己
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Fukuoka University
Immunochondria: Study on a center role in the innate immunityPrincipal Investigator
- Principal Investigator
  
  小柴琢己
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Fukuoka University
Exploratory research on the mitochondrial zone responsible for innate immunityPrincipal Investigator
- Principal Investigator
  
  小柴琢己
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Fukuoka University
Analysis of mitochondrial response zone involved in innate immunityPrincipal Investigator
- Principal Investigator
  
  小柴琢己
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Fukuoka University
  Kyushu University
Structural modifications of mitochondrial dynamics; antiviral innate immunityPrincipal Investigator
- Principal Investigator
  
  Koshiba Takumi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pathology, Infection/Immunology, and related fields
- Research Institution
  Kyushu University
Mechanism of mitochondrial dynamics and its physiological relevancePrincipal Investigator
- Principal Investigator
  
  Koshiba Takumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Fukuoka University
  Kyushu University
ウイルスタンパク質とミトコンドリアとの相互作用解析Principal Investigator
- Principal Investigator
  
  小柴琢己
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Mitochondrial dynamics in mammals and its molecular mechanismPrincipal Investigator
- Principal Investigator
  
  Koshiba Takumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyushu University
Does enzymatic activity involve in mitochondrial movement?Principal Investigator
- Principal Investigator
  
  Koshiba Takumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bio-related chemistry
- Research Institution
  Kyushu University
ミトコンドリア・宿主間コミュニケーションによる抗ウイルス免疫機構の解析Principal Investigator
- Principal Investigator
  
  小柴琢己
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Structural basis of mitochondrial proteins involved in anti-viral innate immunityPrincipal Investigator
- Principal Investigator
  
  KOSHIBA TAKUMI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
The role of mitochondrial proteins involved in the innate immunityPrincipal Investigator
- Principal Investigator
  
  KOSHIBA Takumi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyushu University
Structural analysis of pattern-recognition proteins involved in innate immunity
- Principal Investigator
  
  KAWABATA Shun-ichiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
リポ多糖認識に伴う生体膜融合及び分泌機構の分子基盤解析Principal Investigator
- Principal Investigator
  
  小柴琢己
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyushu University
Structure-function analysis of Pattem-recognition Proteins
- Principal Investigator
  
  KAWABATA Shunichiro
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KYUSHU UNIVERCTIY

[Book] ミトコンドリアダイナミクス～機能研究から疾患・老化まで～2021
- Author(s)
  平田聖里菜、錦織充広、小柴琢己　ほか
- Total Pages
  458
- Publisher
  (株)エヌ・ティー・エス
- Data Source
  KAKENHI-PUBLICLY-20H04914
[Book] ミトコンドリアダイナミクス～機能研究から疾患・老化まで～2021
- Author(s)
  平田聖里菜、錦織充広、小柴琢己　ほか
- Total Pages
  458
- Publisher
  (株)エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-21K19389
[Journal Article] Increased ROS levels in mitochondrial outer membrane protein Mul1-deficient oocytes result in abnormal preimplantation embryogenesis2024
- Author(s)
  Nakai, A., Fukushima, Y., Yamamoto, A., Amatsu, Y., Chen, X., Nishigori, M., Yoshioka, Y., Kaneko, M., Koshiba, T., and Watanabe, T.
- Journal Title
  
  FEBS Lett.
  
  Volume: - Issue: 14 Pages: 1740-1752
- DOI
  10.1002/1873-3468.14876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19389
[Journal Article] Increased ROS levels in mitochondrial outer membrane protein Mul1-deficient oocytes result in abnormal preimplantation embryogenesis2024
- Author(s)
  Nakai, A., Fukushima, Y., Yamamoto, A., Amatsu, Y., Chen, X., Nishigori, M., Yoshioka, Y., Kaneko, M., Koshiba, T., and Watanabe, T.
- Journal Title
  
  FEBS Lett.
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K26789
[Journal Article] 自然免疫応答におけるミトコンドリアの役割2022
- Author(s)
  平田聖里菜、小柴琢己
- Journal Title
  
  医学のあゆみ
  
  Volume: 281 Pages: 1157-1161
- Data Source
  KAKENHI-PROJECT-21K19389
[Journal Article] ミトコンドリアと免疫機能2021
- Author(s)
  平田聖里菜、小柴琢己
- Journal Title
  
  FOOD Style 21
  
  Volume: 25 Pages: 39-41
- Data Source
  KAKENHI-PUBLICLY-20H04914
[Journal Article] Mitochondrial reactive zones in antiviral innate immunity2021
- Author(s)
  Yasukawa Kai、Koshiba Takumi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1865 Issue: 3 Pages: 129839-129839
- DOI
  10.1016/j.bbagen.2020.129839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04914, KAKENHI-PROJECT-21K19389
[Journal Article] ミトコンドリアと免疫機能2021
- Author(s)
  平田聖里菜、小柴琢己
- Journal Title
  
  FOOD Style 21
  
  Volume: 25 Pages: 39-41
- Data Source
  KAKENHI-PROJECT-21K19389
[Journal Article] MAVS is energized by Mff which senses mitochondrial metabolism via AMPK for acute antiviral immunity2020
- Author(s)
  Hanada Yuki、Ishihara Naotada、Wang Lixiang、Otera Hidenori、Ishihara Takaya、Koshiba Takumi、Mihara Katsuyoshi、Ogawa Yoshihiro、Nomura Masatoshi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 5711-5711
- DOI
  10.1038/s41467-020-19287-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08921, KAKENHI-PUBLICLY-20H04914, KAKENHI-PROJECT-19H01054, KAKENHI-PROJECT-18K06141
[Journal Article] 抗ウイルス自然免疫におけるミトコンドリアの応答ゾーン2020
- Author(s)
  錦織充広、小柴琢己
- Journal Title
  
  福岡医学雑誌
  
  Volume: 111 Pages: 77-85
- NAID
  120006890296
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04914
[Journal Article] Mitochondria: In the Cross Fire of SARS-CoV-2 and Immunity2020
- Author(s)
  Burtscher Johannes、Cappellano Giuseppe、Omori Akiko、Koshiba Takumi、Millet Gregoire P.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 10 Pages: 101631-101631
- DOI
  10.1016/j.isci.2020.101631
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04914
[Journal Article] The microRNAs miR-302b and miR-372 regulate mitochondrial metabolism via the SLC25A12 transporter, which controls MAVS-mediated antiviral innate immunity.2020
- Author(s)
  Yasukawa K, Kinoshita D, Yaku K, Nakagawa T, Koshiba T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 295(2) Issue: 2 Pages: 444-457
- DOI
  10.1074/jbc.ra119.010511
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17921, KAKENHI-PUBLICLY-18H04863, KAKENHI-PROJECT-17H03667, KAKENHI-PROJECT-17K08653, KAKENHI-PUBLICLY-20H04914
[Journal Article] Influenza Virus-Induced Oxidized DNA Activates Inflammasomes2020
- Author(s)
  Moriyama Miyu、Nagai Minami、Maruzuru Yuhei、Koshiba Takumi、Kawaguchi Yasushi、Ichinohe Takeshi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 7 Pages: 101270-101270
- DOI
  10.1016/j.isci.2020.101270
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07511, KAKENHI-PUBLICLY-20H04914, KAKENHI-PROJECT-20H03491, KAKENHI-PROJECT-19J00215, KAKENHI-PROJECT-19K21256
[Journal Article] Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses2019
- Author(s)
  Moriyama Miyu、Koshiba Takumi、Ichinohe Takeshi
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 4624-4624
- DOI
  10.1038/s41467-019-12632-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04863, KAKENHI-PROJECT-17H03667, KAKENHI-PROJECT-19J00215
[Journal Article] Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region2019
- Author(s)
  Yoshinaka Takahiro、Kosako Hidetaka、Yoshizumi Takuma、Furukawa Ryo、Hirano Yu、Kuge Osamu、Tamada Taro、Koshiba Takumi
- Journal Title
  
  iScience
  
  Volume: 19 Pages: 1065-1078
- DOI
  10.1016/j.isci.2019.08.056
- NAID
  120006959760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04863, KAKENHI-PUBLICLY-19H04966, KAKENHI-PROJECT-17H03667
[Journal Article] ミトコンドリアと抗ウイルス自然免疫シグナル2019
- Author(s)
  小柴琢己
- Journal Title
  
  実験医学
  
  Volume: 37 Pages: 145-151
- Data Source
  KAKENHI-PUBLICLY-18H04863
[Journal Article] Mass spectrometry-based methods for analysing the mitochondrial interactome in mammalian cells2019
- Author(s)
  Koshiba Takumi、Kosako Hidetaka
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 167 Issue: 3 Pages: 225-231
- DOI
  10.1093/jb/mvz090
- NAID
  120006959753
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PUBLICLY-18H04863, KAKENHI-PUBLICLY-19H04966, KAKENHI-PROJECT-17H03667
[Journal Article] ミトコンドリアと抗ウイルス自然免疫シグナル2019
- Author(s)
  小柴琢己
- Journal Title
  
  実験医学
  
  Volume: 37 Pages: 145-151
- Data Source
  KAKENHI-PROJECT-17H03667
[Journal Article] Two Conserved Amino Acids within the NSs of Severe Fever with Thrombocytopenia Syndrome Phlebovirus Are Essential for Anti-interferon Activity2018
- Author(s)
  Moriyama Miyu、Igarashi Manabu、Koshiba Takumi、Irie Takashi、Takada Ayato、Ichinohe Takeshi
- Journal Title
  
  Journal of Virology
  
  Volume: 92 Issue: 19
- DOI
  10.1128/jvi.00706-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19560, KAKENHI-PUBLICLY-18H04863, KAKENHI-PROJECT-16H05193, KAKENHI-PROJECT-16H05197, KAKENHI-PROJECT-17H03667, KAKENHI-PROJECT-17J00854, KAKENHI-PROJECT-17K19561
[Journal Article] ミトコンドリアを介した自然免疫応答2018
- Author(s)
  小柴琢己
- Journal Title
  
  医学のあゆみ
  
  Volume: 265 Pages: 1101-1107
- Data Source
  KAKENHI-PROJECT-17K19561
[Journal Article] Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication.2018
- Author(s)
  Maruzuru Y, Ichinohe T, Sato R, Miyake K, Okano T, Suzuki T, Koshiba T, Koyanagi N, Tsuda S, Watanabe M, Arii J, Kato A, Kawaguchi Y.
- Journal Title
  
  Cell Host Microbe.
  
  Volume: 23 Issue: 2 Pages: 254-265
- DOI
  10.1016/j.chom.2017.12.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08851, KAKENHI-PROJECT-16K15280, KAKENHI-PROJECT-26293102, KAKENHI-PROJECT-26713017, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06433, KAKENHI-PROJECT-16H06388, KAKENHI-PROJECT-15H04730, KAKENHI-PROJECT-16H05193, KAKENHI-PROJECT-15J09601, KAKENHI-PROJECT-26460548, KAKENHI-PROJECT-15K15138, KAKENHI-PROJECT-17K19549, KAKENHI-PUBLICLY-18H04863, KAKENHI-PUBLICLY-18H04968, KAKENHI-PROJECT-17H03667, KAKENHI-PROJECT-17K19561, KAKENHI-PROJECT-17H05069, KAKENHI-PROJECT-16H06276
[Journal Article] ミトコンドリアを介した自然免疫応答2018
- Author(s)
  小柴琢己
- Journal Title
  
  医学のあゆみ
  
  Volume: 265 Pages: 1101-1107
- Data Source
  KAKENHI-PUBLICLY-18H04863
[Journal Article] ミトコンドリアを介した自然免疫応答2018
- Author(s)
  小柴琢己
- Journal Title
  
  医学のあゆみ
  
  Volume: 265 Pages: 1101-1107
- Data Source
  KAKENHI-PROJECT-17H03667
[Journal Article] インフルエンザウイルス感染に伴うミトコンドリア形態への影響2017
- Author(s)
  小柴琢己
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 47 Pages: 42-44
- Data Source
  KAKENHI-PROJECT-17H03667
[Journal Article] RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity2017
- Author(s)
  Yoshizumi T, Imamura H, Taku T, Kuroki T, Kawaguchi A, Ishikawa K, Nakada K, Koshiba T
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 5379-5379
- DOI
  10.1038/s41598-017-05808-w
- NAID
  120007128833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19561, KAKENHI-PROJECT-16H04678, KAKENHI-PROJECT-16H05192, KAKENHI-PROJECT-17H03667, KAKENHI-PROJECT-15J04145, KAKENHI-PROJECT-16K14709, KAKENHI-PROJECT-16K14719, KAKENHI-PROJECT-17H03654
[Journal Article] Evaluation of Mitochondrial Respiratory Activity Using a FRET-based Indicator for Intracellular ATP2017
- Author(s)
  小柴琢己、今村博臣
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 57 Issue: 5 Pages: 268-270
- DOI
  10.2142/biophys.57.268
- NAID
  130006100204
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19561, KAKENHI-PROJECT-17H03667
[Journal Article] インフルエンザウイルス感染に伴うミトコンドリア形態への影響2017
- Author(s)
  小柴琢己
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 47 Pages: 42-44
- Data Source
  KAKENHI-PROJECT-17K19561
[Journal Article] ミトコンドリア・ダイナミクスと抗ウイルス自然免疫2016
- Author(s)
  小柴琢己
- Journal Title
  
  細胞
  
  Volume: 48 Pages: 39-41
- Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Journal Article] ミトコンドリア・ダイナミクスと抗ウイルス自然免疫2016
- Author(s)
  小柴琢己
- Journal Title
  
  細胞
  
  Volume: 48 Pages: 39-41
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26291032
[Journal Article] ウイルスタンパク質とミトコンドリアとの相互作用2016
- Author(s)
  吉住拓馬、安川開、小柴琢己
- Journal Title
  
  福岡医学雑誌
  
  Volume: 107 Pages: 148-154
- NAID
  120005893255
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Journal Article] ウイルスタンパク質とミトコンドリアとの相互作用2016
- Author(s)
  吉住拓馬、安川開、小柴琢己
- Journal Title
  
  福岡医学雑誌
  
  Volume: 107 Pages: 148-154
- NAID
  120005893255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26291032
[Journal Article] A型インフルエンザウイルスタンパク質PB1-F2とミトコンドリアとの相互作用2015
- Author(s)
  吉住拓馬、小柴琢己
- Journal Title
  
  生化学
  
  Volume: 87 Pages: 144-148
- NAID
  40020383817
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26620135
[Journal Article] 抗ウイルス自然免疫におけるミトコンドリアの役割2015
- Author(s)
  小柴琢己
- Journal Title
  
  細胞工学
  
  Volume: 34 Pages: 571-575
- Data Source
  KAKENHI-PROJECT-26620135
[Journal Article] A型インフルエンザウイルスタンパク質PB1-F2とミトコンドリアとの相互作用2015
- Author(s)
  吉住拓馬、小柴琢己
- Journal Title
  
  生化学
  
  Volume: 87 Pages: 144-148
- NAID
  40020383817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26291032
[Journal Article] Protein-protein interactions of mitochondrial-associated protein via bioluminescence resonance energy transfer2015
- Author(s)
  Koshiba, T.
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 12 Pages: 31-35
- NAID
  130005098799
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26291032
[Journal Article] 抗ウイルス自然免疫におけるミトコンドリアの役割2015
- Author(s)
  小柴琢己
- Journal Title
  
  細胞工学
  
  Volume: 34 Pages: 571-575
- Data Source
  KAKENHI-PROJECT-26291032
[Journal Article] Interaction between an Influenza A viral protein PB1-F2 and mitochondria2015
- Author(s)
  吉住拓馬、小柴琢己
- Journal Title
  
  生化学
  
  Volume: 87 Issue: 1 Pages: 144-148
- DOI
  10.14952/SEIKAGAKU.2015.870144
- NAID
  40020383817
- ISSN
  0037-1017
- Year and Date
  2015-02-25
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25115515
[Journal Article] 抗ウイルス自然免疫におけるミトコンドリアの役割2015
- Author(s)
  小柴琢己
- Journal Title
  
  細胞工学
  
  Volume: 34 Pages: 571-575
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Journal Article] Protein-protein interactions of mitochondrial-associated protein via bioluminescence resonance energy transfer2015
- Author(s)
  Koshiba, T.
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 12 Pages: 31-35
- NAID
  130005098799
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26620135
[Journal Article] A型インフルエンザウイルスタンパク質PB1-F2とミトコンドリアとの相互作用2015
- Author(s)
  吉住拓馬、小柴琢己
- Journal Title
  
  生化学
  
  Volume: 87 Pages: 144-148
- NAID
  40020383817
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Journal Article] The N-terminal Arg residue is essential for autocatalytic activation of a lipopolysaccharide-responsive protease zymogen2014
- Author(s)
  Kobayashi, Y., Shiga, T., Shibata, T., Sako, M., Maenaka, K., Koshiba, T., Mizumura, H., Oda, T., and Kawabata, S.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Issue: 37 Pages: 25987-25995
- DOI
  10.1074/jbc.m114.586933
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25115515, KAKENHI-PROJECT-26291032, KAKENHI-PROJECT-26860333
[Journal Article] Influenza A virus protein PB1-F2 translocates into mitochondria via Tom40 channels and impairs innate immunity2014
- Author(s)
  Yoshizumi, T., Ichinohe, T., Sasaki, O., Otera, H., Kawabata, S., Mihara, K., and #Koshiba, T.
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 4713-4713
- DOI
  10.1038/ncomms5713
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25115515, KAKENHI-PROJECT-25440088, KAKENHI-PROJECT-25713018, KAKENHI-PROJECT-26291032, KAKENHI-PROJECT-26620135
[Journal Article] Loss of Miro1-directed retrograde mitochondrial movement results in a novel murine model for neuron disease2014
- Author(s)
  Nguyen, T.T., Oh, S.S., Weaver, D., Lewandowska, A., Maxfield, D., Schuler, M.H., Smith, N.K., Macfarlane, J., Saunders, G., Palmer, C.A., Debattisti, V., Koshiba, T., Pulst, S., Feldman, E.L., Hajnóczky, G., and Shaw, J.M.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 111 Issue: 35
- DOI
  10.1073/pnas.1402449111
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25115515, KAKENHI-PROJECT-26291032, KAKENHI-PROJECT-26620135
[Journal Article] Fis1 acts as mitochondrial recruitment factor for TBC1D15 that involved in regulation of mitochondrial morphology2013
- Author(s)
  Onoue, K., Jofuku, A., Ban-Ishihara, R., Ishihara, T., Maeda, M., Koshiba, T., Itoh, T., Fukuda, M., Otera, H., Oka, T., Takano, H., Mizushima, N., Mihara, K., and Ishihara, N.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 126 Pages: 176-185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770099
[Journal Article] ミトコンドリアと抗ウイルス免疫2013
- Author(s)
  小柴琢己
- Journal Title
  
  生化学
  
  Volume: 85 Pages: 336-344
- NAID
  10031177325
- Data Source
  KAKENHI-PROJECT-24770099
[Journal Article] Fis1 acts as mitochondrial recruitment of TBC1D15 that involved in regulation of mitochondrial morphology2013
- Author(s)
  K. Onoue et al.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 126 Issue: 1 Pages: 176-186
- DOI
  10.1242/jcs.111211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370071, KAKENHI-PROJECT-23570232, KAKENHI-PROJECT-23770216, KAKENHI-PROJECT-23770231, KAKENHI-PROJECT-24370077, KAKENHI-PROJECT-24657138, KAKENHI-PROJECT-24770099, KAKENHI-PROJECT-24770133
[Journal Article] A structural perspective of the MAVS-regulatory mechanism on the mitochondrial outer membrane2013
- Author(s)
  Sasaki, O., Yoshizumi, T., Kuboyama, M., Ishihara, T., Suzuki, E., Kawabata, S., and *Koshiba, T.
- Journal Title
  
  Biochim. Biophys. Acta - Mol. Cell Res.
  
  Volume: 1833 Issue: 5 Pages: 1017-1027
- DOI
  10.1016/j.bbamcr.2013.01.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770099, KAKENHI-PUBLICLY-25115515
[Journal Article] ミトコンドリアと抗ウイルス免疫2013
- Author(s)
  小柴琢己
- Journal Title
  
  生化学
  
  Volume: 85 Pages: 336-344
- NAID
  10031177325
- Data Source
  KAKENHI-PUBLICLY-25115515
[Journal Article] Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-κB-like transcription factor Relish.2013
- Author(s)
  Shibata, T., Sekihara, S., Fujikawa, T., Miyaji, R., Maki, K., Ishihara, T., Koshiba, T., and Kawabata, S.
- Journal Title
  
  Science Signaling
  
  Volume: 6 Issue: 285 Pages: 1-9
- DOI
  10.1126/scisignal.2003970
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117712, KAKENHI-PROJECT-24570164, KAKENHI-PROJECT-24770099
[Journal Article] Mitochondrial protein mitofusin 2 is required for NLRP3 inflammasome activation after RNA virus infection.2013
- Author(s)
  Ichinohe T, Yamazaki T, Koshiba T, Yanagi Y.
- Journal Title
  
  Proceeding National Academic Science USA
  
  Volume: 110(44) Issue: 44 Pages: 17963-17968
- DOI
  10.1073/pnas.1312571110
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-24770099, KAKENHI-PUBLICLY-25115515, KAKENHI-PROJECT-25713018
[Journal Article] Mitochondrial-mediated antiviral immunity2013
- Author(s)
  *Koshiba, T.
- Journal Title
  
  Biochim. Biophys. Acta - Mol. Cell Res.
  
  Volume: 1833 Issue: 1 Pages: 225-232
- DOI
  10.1016/j.bbamcr.2012.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770099, KAKENHI-PUBLICLY-25115515
[Journal Article] Microbe-specific c3b deposition in the horseshoe crab complement system in a c2/factor B-dependent or-independent manner2012
- Author(s)
  Tagawa K, Yoshihara T, Shibata T, Kitazaki K, Endo Y, Fujita T, Koshiba T and Kawabata S.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 5 Pages: e36783-e36783
- DOI
  10.1371/journal.pone.0036783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570144, KAKENHI-PROJECT-23890147, KAKENHI-PROJECT-24770099
[Journal Article] ミトコンドリア外膜上でのウイルス免疫制御機構.2010
- Author(s)
  *小柴琢己
- Journal Title
  
  生化学(日本生化学会) 82
  
  Pages: 135-139
- NAID
  10026300531
- Data Source
  KAKENHI-PROJECT-20770123
[Journal Article] ミトコンドリア外膜タンパク質Mitofusin2によるウイルス免疫制御機構2010
- Author(s)
  小柴琢己
- Journal Title
  
  実験医学(羊土社) 28
  
  Pages: 429-432
- Data Source
  KAKENHI-PROJECT-20770123
[Journal Article] ミトコンドリア外膜上でのウイルス免疫制御機構.2010
- Author(s)
  小柴琢己
- Journal Title
  
  生化学(日本生化学会) 82
  
  Pages: 135-139
- NAID
  10026300531
- Data Source
  KAKENHI-PROJECT-20770123
[Journal Article] ミトコンドリア外膜タンパク質Mitofusin 2によるウイルス免疫制御機構.2010
- Author(s)
  *小柴琢己
- Journal Title
  
  実験医学(羊土社) 28
  
  Pages: 429-432
- Data Source
  KAKENHI-PROJECT-20770123
[Journal Article] Mitofusin 2 inhibits mitochondrial antiviral signaling.2009
- Author(s)
  Yasukawa, K., Oshiumi, H., Takeda, M., Ishihara, N., Yanagi, Y., Seya, T., Kawabata, S., *Koshiba, T.
- Journal Title
  
  Science Signaling 2
- Data Source
  KAKENHI-PROJECT-20770123
[Journal Article] Factor C acts as a lipopolysaccharide-responsive C3 convertase in horseshoe crab complement activation2008
- Author(s)
  Ariki, S., Takahara, S., Shibata, T., Fukuoka, T., Ozaki, A., Endo, Y., Fujita, T., Koshiba, T., and Kawabata, S.
- Journal Title
  
  J.Immunology 181
  
  Pages: 7794-8001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370045
[Journal Article] A cysteine-rich protein from an arthropod stabilizes clotting mesh and immobilizes bacteria at injury sites2007
- Author(s)
  Matsuda, Y.・Osaki, T.・Hashii, T.・Koshiba, T.・Kawabata, S.
- Journal Title
  
  The Journal of Bilolgical Chemistry 282
  
  Pages: 33545-33552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770137
[Journal Article] A structural perspective on the interaction between lipopolysaccharide and Factor C, a receptor involved in recognition of Gram-negative bacteria.2007
- Author(s)
  Koshiba, T. et al.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 3962-3967
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13143203
[Journal Article] A structural perspective on the interaction between lipopolysaccharide and Factor C, a receptor involved in recognition of Gram-negative bacteria.2007
- Author(s)
  Koshiba, T. et al.
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 3962-3967
- Data Source
  KAKENHI-PROJECT-18370045
[Journal Article] A structural pcrspective on the interaction between lipopolysaccharide and Factor C, a receptor involved in recognition of Gram-negative bacteria2007
- Author(s)
  Koshiba, T.・Hashii, T.・Kawabata, S.
- Journal Title
  
  The Journal of Bilolgical Chemistry 282
  
  Pages: 3962-3967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770137
[Journal Article] An arthropod cuticular chitin-binding protein endows injured sites with transglutaminase-dependent mesh2007
- Author(s)
  Matsuda, Y.・Koshiba, T.・Osaki, T.・Suyama, H.・Arisaka., F.・Toh, Y.・Kawabata, S.
- Journal Title
  
  The Journal of Bilolgical Chemistry 282
  
  Pages: 37316-37324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770137
[Journal Article] A structural perspective on the interaction between lipopolysaccharide and Factor C, a receptor involved in recognition of Gram-negative bacteria2007
- Author(s)
  Koshiba, T., Hashii, T., and Kawabata, S.
- Journal Title
  
  J.Biol. Chem. 282
  
  Pages: 3962-3967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370045
[Journal Article] A structural perspective on the interaction between lipopolysaccharide and Factor C, a receptor involved in recognition of Gram-negative bacteria2007
- Author(s)
  Takumi Koshiba, Tomoyuki Hashii, Shunichiro Kawabata
- Journal Title
  
  The Journal of Biological Chemistry 282
  
  Pages: 3962-3967
- Data Source
  KAKENHI-PROJECT-18770137
[Journal Article] An arthropod cuticular chitin-binding protein endows injured sites with transglutaminase-dependent mesh2007
- Author(s)
  Matusda, Y., Koshiba, T., Osaki, T., Suyama, H., Arisaka, F., Toh, Y., and Kawabata, S.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 37316-37324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370045
[Journal Article] A structural perspective on the interaction between lipopolysaccharide and Factor C, a receptor involved in recognition of Gram-negative bacteria.2007
- Author(s)
  Koshiba, T. et al.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 3962-3967
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13143203
[Journal Article] A cysteine-rich protein from an arthropod stabilizes clotting mesh and immobilizes bacteria at injured sites2007
- Author(s)
  Matsuda, Y., Osaki, T., Hashii, T., Koshiba, T., and Kawabata, S.
- Journal Title
  
  J.Biol.Chem. 282
  
  Pages: 33545-33552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] MicroRNAs target mitochondrial-mediated antiviral innate immunity by regulating mitochondrial dynamics and metabolic demand2024
- Author(s)
  Takumi Koshiba
- Organizer
  MitoClub Seminars 2024 at the Max-Planck-Institute for Biology of Ageing
- Invited
- Data Source
  KAKENHI-PROJECT-21K19389
[Presentation] MicroRNAs target mitochondrial-mediated antiviral innate immunity by regulating mitochondrial dynamics and metabolic demand2024
- Author(s)
  Takumi Koshiba
- Organizer
  MitoClub Seminars 2024 at the Max-Planck-Institute for Biology of Ageing
- Invited
- Data Source
  KAKENHI-PROJECT-23K26789
[Presentation] Mitochondrial-mediated antiviral innate immunity in mammals2023
- Author(s)
  Takumi Koshiba
- Organizer
  University of Ulsan - Fukuoka University International Joint Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-23K26789
[Presentation] Mitochondrial-mediated antiviral innate immunity in mammals2023
- Author(s)
  Takumi Koshiba
- Organizer
  University of Ulsan - Fukuoka University International Joint Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-21K19389
[Presentation] Mitochondria and parasite interactions2022
- Author(s)
  小柴琢己
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19389
[Presentation] ノンコーディングRNAによるミトコンドリア動態・代謝の調節2021
- Author(s)
  小柴琢己
- Organizer
  第20回ミトコンドリア学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04914
[Presentation] 質量分析法によるミトコンドリアタンパク質複合体の解析2021
- Author(s)
  小柴琢己
- Organizer
  第59回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04914
[Presentation] ノンコーディングRNAによるミトコンドリア動態・代謝の調節2021
- Author(s)
  小柴琢己
- Organizer
  第20回ミトコンドリア学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19389
[Presentation] 質量分析法によるミトコンドリアタンパク質複合体の解析2021
- Author(s)
  小柴琢己
- Organizer
  第59回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19389
[Presentation] miRNAを介したミトコンドリアの機能制御2020
- Author(s)
  小柴琢己
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04914
[Presentation] ミトコンドリアにおける自然免疫応答ゾーンの解析2019
- Author(s)
  小柴琢己
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04863
[Presentation] ミトコンドリアにおける自然免疫応答ゾーンの解析2019
- Author(s)
  小柴琢己
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] ミトコンドリアを介した抗ウイルス自然免疫2019
- Author(s)
  小柴琢己
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04863
[Presentation] ミトコンドリアを介した抗ウイルス自然免疫2019
- Author(s)
  小柴琢己
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] Structure-function analysis of the prohibitin complexes in mitochondria2019
- Author(s)
  小柴琢己
- Organizer
  第71回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04863
[Presentation] Structural basis of mitochondrial scaffolds by prohibitin complexes2019
- Author(s)
  Takumi Koshiba
- Organizer
  The 16th Conference of Asian Society for Mitochondrial Research and Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] Structural basis of mitochondrial scaffolds by prohibitin complexes2019
- Author(s)
  Takumi Koshiba
- Organizer
  The 16th Conference of Asian Society for Mitochondrial Research and Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04863
[Presentation] Structure-function analysis of the prohibitin complexes in mitochondria2019
- Author(s)
  小柴琢己
- Organizer
  第71回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] Mitochondrial-mediated antiviral innate immunity in mammals2018
- Author(s)
  Takumi Koshiba
- Organizer
  The 15th Conference of Asian Society for Mitochondrial Research and Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] Mitochondrial-mediated antiviral innate immunity in mammals2018
- Author(s)
  Takumi Koshiba
- Organizer
  The 15th Conference of Asian Society for Mitochondrial Research and Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19561
[Presentation] Mitochondrial-mediated antiviral innate immunity in mammals2018
- Author(s)
  Takumi Koshiba
- Organizer
  The 3rd Asian Invertebrate Immunity Symposium 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] Mitochondrial-mediated antiviral innate immunity in mammals2018
- Author(s)
  Takumi Koshiba
- Organizer
  The 3rd Asian Invertebrate Immunity Symposium 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19561
[Presentation] Mitochondrial-mediated antiviral innate immunity in mammals2018
- Author(s)
  Takumi Koshiba
- Organizer
  The 15th Conference of Asian Society for Mitochondrial Research and Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04863
[Presentation] Mitochondrial-mediated antiviral innate immunity in mammals2018
- Author(s)
  Takumi Koshiba
- Organizer
  The 3rd Asian Invertebrate Immunity Symposium 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04863
[Presentation] ミトコンドリアタンパク質による膜構造への影響2017
- Author(s)
  小柴琢己
- Organizer
  生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] ミトコンドリアの呼吸活性と抗ウイルス自然免疫2017
- Author(s)
  小柴琢己
- Organizer
  第69回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] ミトコンドリア・ダイナミクスの生理機能解析2017
- Author(s)
  小柴琢己
- Organizer
  平成29年度「AMED難治性疾患実用化研究事業・ミトコンドリアシンポジウム」
- Invited
- Data Source
  KAKENHI-PROJECT-17H03667
[Presentation] ミトコンドリア・ダイナミクスの生理機能解析2017
- Author(s)
  小柴琢己
- Organizer
  平成29年度「AMED難治性疾患実用化研究事業・ミトコンドリアシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19561
[Presentation] ミトコンドリアの呼吸活性と抗ウイルス自然免疫2017
- Author(s)
  小柴琢己
- Organizer
  第69回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19561
[Presentation] ミトコンドリアタンパク質による膜構造への影響2017
- Author(s)
  小柴琢己
- Organizer
  生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-17K19561
[Presentation] Mitochondrial-mediated antiviral immunity and oxidative phosphorylation2016
- Author(s)
  小柴琢己
- Organizer
  第54回日本生物物理学会年
- Place of Presentation
  つくば国際会議場
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Presentation] Mitochondrial respiration and MAVS-mediated antiviral innate immunity2016
- Author(s)
  Takumi Koshiba
- Organizer
  International Symposium on "Molecular Basis of Virus-Host Interactions"
- Place of Presentation
  Sapporo
- Year and Date
  2016-10-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291032
[Presentation] Mitochondrial-mediated antiviral immunity and oxidative phosphorylation2016
- Author(s)
  小柴琢己
- Organizer
  第54回日本生物物理学会年
- Place of Presentation
  つくば国際会議場
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26291032
[Presentation] Mitochondrial-mediated antiviral innate immunity and oxidative phosphorylation2016
- Author(s)
  Takumi Koshiba
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine
- Place of Presentation
  Tokyo
- Year and Date
  2016-10-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Presentation] Mitochondrial respiration and MAVS-mediated antiviral innate immunity2016
- Author(s)
  Takumi Koshiba
- Organizer
  International Symposium on "Molecular Basis of Virus-Host Interactions"
- Place of Presentation
  Sapporo
- Year and Date
  2016-10-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Presentation] Mitochondrial-mediated antiviral innate immunity and oxidative phosphorylation2016
- Author(s)
  Takumi Koshiba
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine
- Place of Presentation
  Tokyo
- Year and Date
  2016-10-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291032
[Presentation] Influenza A viral protein PB1-F2 and mitochondria2015
- Author(s)
  Takumi Koshiba
- Organizer
  The 5th Annual World Congress of Molecular & Cell Biology (CMCB-2015)
- Place of Presentation
  Nanjing, China
- Year and Date
  2015-04-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291032
[Presentation] Mitochondria and antiviral signaling2015
- Author(s)
  小柴琢己
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Presentation] Mitochondria and antiviral signaling2015
- Author(s)
  小柴琢己
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26620135
[Presentation] Mitochondria and antiviral signaling2015
- Author(s)
  小柴琢己
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26291032
[Presentation] Influenza A viral protein PB1-F2 and mitochondria2015
- Author(s)
  Takumi Koshiba
- Organizer
  The 5th Annual World Congress of Molecular & Cell Biology (CMCB-2015)
- Place of Presentation
  Nanjing, China
- Year and Date
  2015-04-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01265
[Presentation] Influenza A viral protein PB1-F2 and mitochondria2015
- Author(s)
  Takumi Koshiba
- Organizer
  The 5th Annual World Congress of Molecular & Cell Biology (CMCB-2015)
- Place of Presentation
  中国・南京
- Year and Date
  2015-04-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26620135
[Presentation] 哺乳動物における抗ウイルス免疫とミトコンドリアとの関係2014
- Author(s)
  小柴琢己
- Organizer
  第25回フォーラム・イン・ドージン
- Place of Presentation
  熊本ホテルキャッスル
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-26291032
[Presentation] 哺乳動物における抗ウイルス免疫とミトコンドリアとの関係2014
- Author(s)
  小柴琢己
- Organizer
  第25回フォーラム・イン・ドージン
- Place of Presentation
  熊本ホテルキャッスル
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PUBLICLY-25115515
[Presentation] Mitochondria and antiviral signaling2013
- Author(s)
  Koshiba, T.
- Organizer
  The 4th International Symposium on Dynamics of Mitochondria (DynaMito2013)
- Place of Presentation
  Okinawa, JAPAN
- Invited
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] ミトコンドリアを介した抗ウイルスシグナル伝達2013
- Author(s)
  小柴琢己
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-25115515
[Presentation] Mitochondria and antiviral signaling2013
- Author(s)
  Koshiba, T.
- Organizer
  The 4th International Symposium on Dynamics of Mitochondria (DynaMito2013)
- Place of Presentation
  Okinawa
- Invited
- Data Source
  KAKENHI-PUBLICLY-25115515
[Presentation] ミトコンドリアを介した抗ウイルスシグナル伝達2013
- Author(s)
  小柴琢己
- Organizer
  第86回日本生化学会大会(会頭 ; 宮園浩平教授)
- Place of Presentation
  パシフィコ横浜, 横浜
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] Mitochondria and antiviral signaling2013
- Author(s)
  Koshiba, T
- Organizer
  The 4th International Symposium on Dynamics of Mitochondria (DynaMito2013) (Organizers ; Prof. Koji Okamoto and Prof. Michael Ryan)
- Place of Presentation
  Okinawa, Japan
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] ミトコンドリアを介した抗ウイルスシグナル伝達2013
- Author(s)
  小柴琢己
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] Mitochondrial-mediated antiviral immunity2012
- Author(s)
  小柴琢己
- Organizer
  第85回日本生化学会大会(会頭 ; 藤木幸夫教授)
- Place of Presentation
  福岡国際会議場, 福岡
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] ミトコンドリア・ダイナミクスの作用機序とその生理的意義2012
- Author(s)
  小柴琢己
- Organizer
  日本生化学会平成24年度奨励賞受賞講演
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] Antiviral innate immunity and mitochondrial function2012
- Author(s)
  Koshiba, T
- Organizer
  The 2nd UCL-JSPS international Symposium"Mitochondria - from the Fundamental Aspects to Medical Importance"(Organizer; Dr. Takehiro Yasukawa)
- Place of Presentation
  UCL Wilkins Building, London, UK
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] ミトコンドリアの自然免疫における役割解明2012
- Author(s)
  小柴琢己
- Organizer
  平成24年度日本生化学会九州支部例会学術奨励賞・受賞講演
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] ミトコンドリアの自然免疫における役割解明2012
- Author(s)
  小柴琢己
- Organizer
  平成24年度日本生化学会九州支部例会学術奨励賞・受賞講演(支部長 ; 寺田成之教授)
- Place of Presentation
  福岡大学, 福岡
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] MAVS signaling and its inhibition2012
- Author(s)
  Koshiba, T
- Organizer
  International Endotoxin and Innate Immunity Society Meeting 2012 (IEIIS2012) (President; Prof. Kensuke Miyake)
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] ミトコンドリアの膜ダイナミクス制御とその生理機能的役割に関する研究2012
- Author(s)
  小柴琢己
- Organizer
  第14回花王研究奨励賞受賞記念講演(主催;公益財団法人花王芸術・科学財団)
- Place of Presentation
  花王すみだ事業所, 東京
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] Antiviral innate immunity and mitochondrial function2012
- Author(s)
  Takumi Koshiba
- Organizer
  The 2nd UCL-JSPS international Symposium “Mitochondria - from the Fundamental Aspects to Medical Importance
- Place of Presentation
  London　英国
- Invited
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] ミトコンドリア・ダイナミクスの作用機序とその生理的意義2012
- Author(s)
  小柴琢己
- Organizer
  日本生化学会平成24年度奨励賞受賞講演(会頭 ; 藤木幸夫教授)
- Place of Presentation
  福岡国際会議場, 福岡
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] MAVS signaling and its inhibition2012
- Author(s)
  Takumi Koshiba
- Organizer
  International Endotoxin and Innate Immunity Society Meeting 2012 (IEIIS2012)
- Place of Presentation
  Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] Mitochondrial-mediated antiviral immunity2012
- Author(s)
  小柴琢己
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24770099
[Presentation] Mitochondrial dynamics and an insight for antiviral innate immunity2010
- Author(s)
  Takumi Koshiba
- Organizer
  International Symposium "Intercellular Recognition and Allogenic Authentication : Perspectives of Reproduction Mechanisms Shared by Animals and Plants"
- Place of Presentation
  SIR Winston Hotel名古屋市
- Year and Date
  2010-01-14
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] Mitochondrial dynamics in mammalian cells and an insight for antiviral innate immunity2010
- Author(s)
  Takumi Koshiba
- Organizer
  STINT workshop on Invertebrates
- Place of Presentation
  ウプサラ市(スウェーデン)
- Year and Date
  2010-03-15
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] Mitochondrial dynamics and an insight for antiviral innate immunity2010
- Author(s)
  Koshiba, T.
- Organizer
  International Symposium "Intercellular Recognition and Allogenic Authentication: Perspectives of Reproduction Mechanisms Shared by Animals and Plants"
- Place of Presentation
  SIR Winston Hotel (Nagoya, Japan)
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] Mitochondrial dynamics in mammalian cells and an insight for antiviral innate immunity2010
- Author(s)
  Koshiba, T.
- Organizer
  STINT workshop on Invertebrates (Uppsala University, Sweden
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] ミトコンドリア外膜上での自然免疫調節機構2009
- Author(s)
  小柴琢己
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本全日空ホテルニュースカイ(熊本)
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] ミトコンドリア外膜上での自然免疫調節機構2009
- Author(s)
  小柴琢己
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本全日空ホテルニュースカイ
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] Mitofusin 2 acts as a negative regulator of mitochondrial antiviral immunity2009
- Author(s)
  Yasukawa, K., Oshiumi, H., Takeda, M., Ishihara, N., Yanagi, Y., Seya, T., Kawabata, S., Koshiba, T.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  バシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] Mitofusin 2 acts as an inhibitor of mitochondrial antiviral signaling2009
- Author(s)
  小柴琢己
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] Mitofusin 2 acts as an inhibitor of mitochondrial antiviral signaling2009
- Author(s)
  小柴琢己
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] Mitofusin 2 acts as a negative regulator of mitochondrial antiviral immunity2009
- Author(s)
  Yasukawa, K., Oshiumi, H., Takeda, M., Ishihara, N., Yanagi, Y., Seya, T., Kawabata, S., Koshiba, T.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] リポ多糖受容体として機能するカブトガニFactor Cの構造機能解明2008
- Author(s)
  小柴琢己, 他
- Organizer
  日本比較免疫学会第20回学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] 自然免疫に関わるミトコンドリア膜蛋白質MAVS機能ドメインの大腸菌による大量発現系構築2008
- Author(s)
  安川開、川畑俊一郎、小柴琢己
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] カブトガニ補体系の活性化機構2008
- Author(s)
  高原修作、有木茂、福岡貴彰、尾崎彩、柴田俊生、遠藤雄一、藤田禎三、小柴琢己、川畑俊一郎
- Organizer
  第81回日本生化学大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] カブトガニ補体系活性化の分子機構2008
- Author(s)
  高原修作、有木茂、福岡貴彰、尾崎彩、小柴琢己、川畑俊一郎
- Organizer
  平成20年度日本生化学会九州支部例会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] 自然免疫に関わるミトコンドリア膜蛋白質MAVS機能ドメインの大腸菌による大量発現系の構築2008
- Author(s)
  安川開、川畑俊一郎、小柴琢己
- Organizer
  BMB2008
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20770123
[Presentation] リポ多糖受容体として機能するカブトガニFactor Cの構造機能解明2008
- Author(s)
  小柴琢己、川畑俊一郎
- Organizer
  日本比較免疫学会第20回学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] リポ多糖受容体として働く膜局在型プロテアーゼ前駆体2007
- Author(s)
  小柴琢己、川畑俊一郎
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] A structural perspective on the interaction between lipopolysaccharide and horseshoe crab factor C.2007
- Author(s)
  Koshiba, T., et. al.
- Organizer
  The 20^<th> Naito Conference on Innate Immunity in Medicine and Biology [III].
- Place of Presentation
  湘南国際村センター、神奈川
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] An arthropod cuticular chitin-binding protein endows injured sites with transglutaminase-dependent mesh2007
- Author(s)
  松田泰幸、小柴琢己、尾崎司、陶山晴香、有坂文雄、川畑俊一郎
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] A structural perspective on the interaction between lipopolysaccharide and horseshoe crab factor C2007
- Author(s)
  Koshiba, T., Shibata, T., and Kawabata, S.
- Organizer
  The 20^<th> Naito Conference on Innate Immunity in Medicine and Biology [III]
- Place of Presentation
  Shonan Village Center
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] リポ多糖受容体として働く膜局在型プロテアーゼ前駆体.2007
- Author(s)
  小柴琢己, 他
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] β-1, 3-グルカン認識ドメインの改変体を応用した真菌検出法2007
- Author(s)
  飯島学、吉光由希子、小柴琢己、中田宗宏、川畑俊一郎
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] カブトガニのLPS受容体Factor C の異物認識ドメインの構造機能解析2007
- Author(s)
  柴田俊生、小柴琢己、川畑俊一郎
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] リボ多糖受容体として働く膜局在型プロテアーゼ前駆体2007
- Author(s)
  小柴琢己、川畑俊一郎
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-18770137
[Presentation] カブトガニ外皮タンパク質カラキシンは、創傷部位においてトランスグルタミナーゼによって架橋され、網目状繊維を形成する2007
- Author(s)
  松田泰幸、小柴琢己, 尾崎司, 陶山晴香, 有坂文雄, 藤義博, 川畑俊一郎
- Organizer
  第19回日本比較免疫学会学術集会
- Place of Presentation
  浜松市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] カブトガニ外皮タンパク質は、トランスグルタミナーゼにより架橋され網目状繊維を形成する2007
- Author(s)
  松田泰幸、小柴琢己、尾崎司、有坂文雄、川畑俊一郎
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-18370045
[Presentation] Influenza A viral protein PB1-F2 and mitochondria
- Author(s)
  Takumi Koshiba
- Organizer
  The 5th Annual World Congress of Molecular & Cell Biology (CMCB-2015)
- Place of Presentation
  Nanjing, China
- Year and Date
  2015-04-25 – 2015-04-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-25115515
[Presentation] ミトコンドリアと抗RNAウイルス自然免疫
- Author(s)
  小柴琢己
- Organizer
  第52回日本生物物理学会年
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26291032
[Presentation] ミトコンドリアと抗RNAウイルス自然免疫
- Author(s)
  小柴琢己
- Organizer
  第52回日本生物物理学会年
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26620135
[Presentation] ミトコンドリアと抗RNAウイルス自然免疫
- Author(s)
  小柴琢己
- Organizer
  第52回日本生物物理学会年
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25115515

1. KAWABATA Shun-ichiro (90183037)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. 渡邊利雄 (60201208)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KAWANO Keiichi (10136492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Kosako Hidetaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. Nakada Kazuto

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. ENDO Yuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 野村政壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 入江崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 藤田禎三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 柳雄介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 伊庭英生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 有井潤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 夜久圭介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 丸鶴雄平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koshiba Takumi 小柴 琢己

KOSHIBA TAKUMI 小柴 琢己

KOSHIBA Takumi 小柴 琢己

Research Projects

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Co-Researchers

感染微生物による宿主ミトコンドリアのマニピュレーションPrincipal Investigator

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Molecular basis of mitochondrial dynamics and their contribution to cellular stress responsesPrincipal Investigator

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Immunochondria: Study on a center role in the innate immunityPrincipal Investigator

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Exploratory research on the mitochondrial zone responsible for innate immunityPrincipal Investigator

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Analysis of mitochondrial response zone involved in innate immunityPrincipal Investigator

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Structural modifications of mitochondrial dynamics; antiviral innate immunityPrincipal Investigator

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Mechanism of mitochondrial dynamics and its physiological relevancePrincipal Investigator

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ウイルスタンパク質とミトコンドリアとの相互作用解析Principal Investigator

Principal Investigator

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Mitochondrial dynamics in mammals and its molecular mechanismPrincipal Investigator

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Does enzymatic activity involve in mitochondrial movement?Principal Investigator

Principal Investigator

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ミトコンドリア・宿主間コミュニケーションによる抗ウイルス免疫機構の解析Principal Investigator

Principal Investigator

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Structural basis of mitochondrial proteins involved in anti-viral innate immunityPrincipal Investigator

Principal Investigator

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The role of mitochondrial proteins involved in the innate immunityPrincipal Investigator

Principal Investigator

Project Period (FY)

Koshiba Takumi 小柴琢己

KOSHIBA TAKUMI 小柴琢己

KOSHIBA Takumi 小柴琢己

[Book] ミトコンドリアダイナミクス～機能研究から疾患・老化まで～2021

[Book] ミトコンドリアダイナミクス～機能研究から疾患・老化まで～2021