Nomura Jun 野村淳

… Alternative Names

野村淳ノムラジュン

NOMURA Jun 野村淳

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Researcher Number	70406528
Other IDs	https://orcid.org/0000-0003-0817-2643
Affiliation (Current)	2024: 神戸大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2024: 神戸大学, 医学研究科, 助教 2021 – 2022: 神戸大学, 医学研究科, 助教 2018 – 2019: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 研究員 2017: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 2013 – 2015: 広島大学, 医歯薬保健学研究院, 特任助教 2012 – 2013: 広島大学, 医歯薬保健学研究院(医), 特任助教 2006 – 2007: 埼玉医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Psychiatric science / Basic Section 49010:Pathological biochemistry-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Neurochemistry/Neuropharmacology Except Principal Investigator Pathological medical chemistry
Keywords	Principal Investigator 自閉症 / 精神疾患 / 発達障害 / ゲノム編集 / コピー数変異 / 染色体工学 / シングルセル解析 / コピー数多型 / 統合失調症 / 染色体操作 … More / 疾患モデル / ES細胞 / ジーンターゲティング / 翻訳 / 神経精神疾患 / 次世代シーケンサー / 神経発達障害 / 神経発達 / 神経生理 / 幹細胞生物学 / オルガノイド / ヒトES細胞 / 神経発達症 / コピー数多型(CNV) / ヒト型疾患モデル動物 / GABA / スパイン / モデルマウス / 薬理 / てんかん / 動物モデル / 神経変性疾患 / CNV / 精神神経疾患 / 脳神経疾患 … More Except Principal Investigator UTF1 / gene targeting / teratoma / cell growth / cellular differentiation / tumorigenic property / pluripotency / embryonic stem cells / ノックアウトマウス / ジーンテゲティング / 分化誘導 / 自己増殖性 / 全能性 / ジーンタゲティング / ジーンターゲティング / 奇形腫 / 細胞増殖 / 細胞分化 / 腫瘍原性 / 多能性 / ES細胞 Less

Phase-specific risk analysis of the translation process in autismPrincipal Investigator
- Principal Investigator
  
  野村淳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kobe University
Identifying drug targets for neuropsychiatric and neurodevelopmental disorders via brain transcriptomePrincipal Investigator
- Principal Investigator
  
  野村淳
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kobe University
Develop and analysis for chromosome mutant micePrincipal Investigator
- Principal Investigator
  
  Nomura Jun
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Institute of Physical and Chemical Research
Comprehensive analysis for animal model of chromosome rearrangementPrincipal Investigator
- Principal Investigator
  
  Nomura Jun
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Hiroshima University
Analysis of mouse and cellular models of psychiatric disorders using a chromosome engineeringPrincipal Investigator
- Principal Investigator
  
  NOMURA Jun
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Hiroshima University
Role of embryonic stem cell-specific coacitvator UTF1 for tumorigenic property of ES cells
- Principal Investigator
  
  OKUDA Akihiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Saitama Medical University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2007 Other

All Journal Article Presentation Book

[Book] 自閉症学2019
- Author(s)
  野村淳，内匠透
- Total Pages
  234
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-17K07119
[Book] 今すぐ始めるゲノム編集2014
- Author(s)
  野村淳，内匠透
- Total Pages
  205
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24791212
[Book] TALEN およびCRISPR/Cas9 を用いた染色体改変法 -簡便迅速かつ高効率な次世代染色体工学-, 実験医学別冊今すぐ始めるゲノム編集2014
- Author(s)
  野村淳, 内匠透
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24791212
[Book] 自閉症のモデル動物, 自閉症の分子基盤, 分子精神医学, Vol.14, No.22014
- Author(s)
  岸本恵子, 野村淳, 内匠透
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24791212
[Book] 分子精神医学ー自閉症の分子基盤ー2014
- Author(s)
  岸本恵子，野村淳，内匠透
- Total Pages
  83
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24791212
[Book] A 15q11-q13 duplication mouse model of autism spectrum disorders. -IV MODEL SYSTEMS AND PATHWAYS IN AUTISM SPECTRUM DISORDERS- The Neuroscience of Autism Spectrum Disorders2013
- Author(s)
  Takumi T., Fukumoto K., Nomura J
- Publisher
  Elsevier Inc
- Data Source
  KAKENHI-PROJECT-24791212
[Book] The Neuroscience of Autism Spectrum Disorders2012
- Author(s)
  Takumi T, Fukumoto K, Nomura J
- Total Pages
  496
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-24791212
[Journal Article] Germ-cell-specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders2023
- Author(s)
  Furukawa S, Nomura J, Hanafusa H, Maegawa H, Takumi T.
- Journal Title
  
  Autism Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07820
[Journal Article] シングルセル，オルガノイド研究による細胞腫特異的自閉症リスク因子の同定2022
- Author(s)
  Nomura J, Takumi T.
- Journal Title
  
  日本生物学的精神医学会誌
  
  Volume: 33 Pages: 48-52
- Open Access
- Data Source
  KAKENHI-PROJECT-21K07820
[Journal Article] A common pathologic mechanism across cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model.2022
- Author(s)
  Lin C-W, Septyaningtrias DE, Chao H-W, Konda M, Atarashi K, Takeshita K, Tamada K, Nomura J, Sassagawa Y, Tanaka K, Nikaido I, Honda K, McHugh TL, Takumi T
- Journal Title
  
  Mol Psychiatr
  
  Volume: in press Issue: 8 Pages: 3343-3354
- DOI
  10.1038/s41380-022-01566-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06316, KAKENHI-PUBLICLY-21H00202, KAKENHI-PROJECT-21H04813, KAKENHI-PROJECT-21K19351, KAKENHI-PROJECT-21K07820, KAKENHI-PLANNED-21H05245, KAKENHI-PROJECT-19K16529
[Journal Article] Autism in a dish: ES cell models of autism with copy number variations reveal cell-type-specific vulnerability2022
- Author(s)
  Nomura Jun、Zuko Amila、Kishimoto Keiko、Mutsumine Hiroaki、Fukatsu Kazumi、Nomura Yoshiko、Liu Xiaoxi、Nakai Nobuhiro、Takahashi Eiki、Kouno Tsukasa、Shin Jay W.、Takumi Toru、ES library team
- Journal Title
  
  BioRxiv
  
  Volume: -
- DOI
  10.1101/2022.02.02.478766
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07820
[Journal Article] Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia.2021
- Author(s)
  Nomura J, Mardo M, Takumi T
- Journal Title
  
  J Neurochem
  
  Volume: 159 Issue: 4 Pages: 647-659
- DOI
  10.1111/jnc.15514
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06316, KAKENHI-PUBLICLY-21H00202, KAKENHI-PROJECT-21H04813, KAKENHI-PROJECT-21K07820, KAKENHI-PROJECT-21K19351
[Journal Article] Transcriptome analysis of human neural cells derived from isogenic embryonic stem cells with 16p11.2 deletion2021
- Author(s)
  Nomura Yoshiko、Nomura Jun、Kamiguchi Hiroyuki、Nishikawa Toru、Takumi Toru
- Journal Title
  
  Neuroscience Research
  
  Volume: N/A Pages: 114-123
- DOI
  10.1016/j.neures.2021.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06463, KAKENHI-PROJECT-16H06316, KAKENHI-PUBLICLY-21H00202, KAKENHI-PROJECT-21H04813, KAKENHI-PROJECT-21K07820
[Journal Article] Reciprocal differentiation via GABAergic components and ASD-related phenotypes in hES with 1q21.1 CNV2021
- Author(s)
  Nomura Yoshiko、Nomura Jun、Nishikawa Toru、Takumi Toru
- Journal Title
  
  BioRxiv
  
  Volume: -
- DOI
  10.1101/2021.09.13.460033
- Open Access
- Data Source
  KAKENHI-PROJECT-21K07820
[Journal Article] Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches.2018
- Author(s)
  Hui K, Katayama Y, Nakayama KI, Nomura J, Sakurai T.
- Journal Title
  
  Neurosci. Biobehav. Rev.
  
  Volume: 印刷中 Pages: 30121-0
- DOI
  10.1016/j.neubiorev.2018.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07119, KAKENHI-PROJECT-18K14822, KAKENHI-PROJECT-18H05215, KAKENHI-PROJECT-16K01948
[Journal Article] Role for neonatal D-serine signaling: prevention of physiological and bahavioral deficits in adult Pick1 knockout mice2016
- Author(s)
  Nomura J, Jaaro-Peled H, Lewis E, Nunez-Abades P, Huppe-Gourgues F, Cash-Padgett T, Emiliani F, Kondo MA, Furuya A, Landek-Salgado MA, Ayhan Y, Kamiya A, Takumi T, Huganir R, Pletnikov M, O'Donnell P, Sawa A
- Journal Title
  
  Mol Psychiatry
  
  Volume: 21 Issue: 3 Pages: 386-393
- DOI
  10.1038/mp.2015.61
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23111005, KAKENHI-PROJECT-25242077, KAKENHI-PROJECT-26870397
[Journal Article] Involvement of Serotonin Transporter Gene Polymorphisms (5-HTT) in Impulsive Behavior in the Japanese Population2015
- Author(s)
  NOMURA, M., KANEKO, M., OKUMA, Y., NOMURA, J., KUSUMI, I., KOYAMA, T., NOMURA, Y
- Journal Title
  
  PLoS One
  
  Volume: 16 Issue: 3 Pages: 1-14
- DOI
  10.1371/journal.pone.0119743
- NAID
  120005745671
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870397, KAKENHI-PROJECT-15K00205, KAKENHI-PROJECT-15K21706
[Journal Article] Animal models of psychiatric disorders that reflect human copy number variation2012
- Author(s)
  Nomura J and Takumi T
- Journal Title
  
  Neural plasticity
  
  Volume: 2012 Pages: 1-9
- DOI
  10.1155/2012/589524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791212, KAKENHI-PLANNED-23111005
[Journal Article] Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion2012
- Author(s)
  Ma TM, Abazyan S, Abazyan B, Nomura J, Yang C, Seshadri S, Sawa A, Snyder SH, Pletnikov MV
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 18 Issue: 5 Pages: 557-567
- DOI
  10.1038/mp.2012.97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791212
[Journal Article] Mutant DISC1 affects methamphetamine-induced sensitization and conditioned place preference : a comorbidity model2012
- Author(s)
  Pogorelov VM, Nomura J, Kim J, Kannan G, Ayhan Y, Yang C, Taniguchi Y, Abazyan B, Valentine H, Krasnova IN, Kamiya A, Cadet JL, Wong DF, Pletnikov MV
- Journal Title
  
  Neuropharmacology
  
  Volume: 62 Issue: 3 Pages: 1242-1251
- DOI
  10.1016/j.neuropharm.2011.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791212
[Presentation] Autism in a dish: ES cell models of autism with copy number variations reveal cell-type-specific vulnerability2023
- Author(s)
  Nomura J. Takumi T
- Organizer
  The 2nd International Symposium Multiscale Brain / MCCS-Asia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07820
[Presentation] ES cell models of autism with copy number variations reveal cell-type-specific vulnerability2023
- Author(s)
  Nomura J.
- Organizer
  The 1st NSN (Neuroscience Network in Kobe) Research Seminar 2023
- Invited
- Data Source
  KAKENHI-PROJECT-21K07820
[Presentation] Autism in a dish., Comprehensive analysis identified CNV- and cell type specific vulnerability of autism spectrum disorder.2023
- Author(s)
  Nomura J, Takumi T.
- Organizer
  第4回理化学研究所BDR・神戸大学合同シンポジウム
- Data Source
  KAKENHI-PROJECT-21K07820
[Presentation] Comprehensive analysis identified CNV- and cell type specific vulnerability across psychiatric disorders2020
- Author(s)
  Jun Nomura
- Organizer
  Takeda Science Foundation, The 10th Takeda Science Foundation International Symposium on PharmaSciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07119
[Presentation] ヒト染色体15q13.3コピー数多型モデルの統合的解析ーヒト染色体15q13.3コピー数多型モデルのトランスクリプトーム解析ー2019
- Author(s)
  Jun Nomura
- Organizer
  喫煙財団研究発表会
- Data Source
  KAKENHI-PROJECT-17K07119
[Presentation] Phenotypic analysis of a mouse model for 15q25.2-25.3 deletion syndrome.2017
- Author(s)
  Nomura, Jun; Kanda, Akifumi; Ellegood, Jacob; Lerch, Jason; Sotomaru, Yusuke; Takumi, Toru
- Organizer
  26th Annual Meeting of the International Behavioral Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07119
[Presentation] Brain structural and behavioral abnormalities in a mouse model for 15q25.2-25.3 microdeletion syndrome2017
- Author(s)
  Nomura, Jun; Kanda, Akifumi; Ellegood, Jacob; Lerch, Jason; Sotomaru, Yusuke; Takumi, Toru
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17K07119
[Presentation] 発達期における D- セリンの役割：Pick1 ノックアウトマウスをモデルとして2015
- Author(s)
  Nomura J, Jaaro-Peled H, Lewis E, Nunez-Abades P, Huppe-Gourgues F, Cash-Padgett T, Emiliani F, Kondo MA, Furuya A, Landek-Salgado MA, Ayhan Y, Kamiya A, Takumi T, Huganir R, Pletnikov M, O'Donnell P, Sawa A.
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  東京（タワーホール船堀）
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-26870397
[Presentation] D-serine production is modulated by DISC1 and Serine racemase interaction in astrocytes, 11th Biennial Meeting of the Asian Pacific Society for Neurochemistry2012
- Author(s)
  Nomura J, Ma TM, Abazyan S, Abazyan B, Seshadri S, Sawa A, Snyder SH, Pletnikov MV
- Organizer
  55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  Kobe, Japan
- Year and Date
  2012-10-01
- Data Source
  KAKENHI-PROJECT-24791212
[Presentation] DISC1 and serine racemase interact in astrocytes to regulate D-serine production2012
- Author(s)
  Abazyan B, Ma TM, Nomura J, Abazyan S, Sawa A, Snyder SH, Pletnikov MV
- Organizer
  3rd Biennial Schizophrenia International Research Conference
- Place of Presentation
  Florence, Italy
- Year and Date
  2012-04-15
- Data Source
  KAKENHI-PROJECT-24791212
[Presentation] D-serine production is modulated by DISC1 and Serine racemase interaction in astrocytes2012
- Author(s)
  Nomura J, Ma TM, Abazyan S, Abazyan B, Seshadri S, Sawa A, Snyder SH, Pletnikov MV
- Organizer
  11th Biennial Meeting of the Asian Pacific Society for Neurochemistry, 55th Annual Meeting of the Japanese Society for Neurochemistry
- Place of Presentation
  Kobe, Japan
- Data Source
  KAKENHI-PROJECT-24791212
[Presentation] DISC1 interacts with Serine racemase to modulate D-serine production in astrocytes2012
- Author(s)
  Pletnikov MV, Ma TM, Nomura J, Abazyan B, Abazyan S, Sawa A, Snyder SH
- Organizer
  3rd Biennial Schizophrenia International Research Conference
- Place of Presentation
  Florence, Italy
- Year and Date
  2012-04-18
- Data Source
  KAKENHI-PROJECT-24791212
[Presentation] Nucleostemin遺伝子の各種幹細胞における機能2007
- Author(s)
  野村淳
- Organizer
  第30回日本分子生物学会、第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390106
[Presentation] Nucleostemin遺伝子の各種幹細胞における機能2007
- Author(s)
  野村淳
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-18390106
[Presentation] Role of Nucleostemin in ES cells and Somatic Stem Cells2007
- Author(s)
  Jun, Nomura
- Organizer
  Biochemistry and Molecular Biology 2007
- Place of Presentation
  Pacifico Yokohama, InterContinental Yokohama Grand
- Year and Date
  2007-12-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390106
[Presentation] ゲノム編集技術による簡便迅速かつ高効率な次世代染色体工学の開発
- Author(s)
  野村淳, 佐久間哲史, 神田暁史, 岸本恵子, 前田知花, 外丸祐介, 山本卓, 内匠透
- Organizer
  第37回分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26870397
[Presentation] ゲノム編集技術による簡便迅速かつ高効率な次世代染色体工学の開発
- Author(s)
  野村淳, 佐久間哲史, 神田暁史, 岸本恵子, 前田知花, 外丸祐介, 山本卓, 内匠透
- Organizer
  第4回ゲノム編集研究会
- Place of Presentation
  広島
- Year and Date
  2014-10-06 – 2014-10-07
- Data Source
  KAKENHI-PROJECT-26870397

1. OKUDA Akihiko (60201993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. MITANI Kohnosuke (10270901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 内匠透

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Nomura Jun 野村 淳

野村 淳 ノムラ ジュン

NOMURA Jun 野村 淳

Research Projects

Research Products

Co-Researchers

Phase-specific risk analysis of the translation process in autismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identifying drug targets for neuropsychiatric and neurodevelopmental disorders via brain transcriptomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Develop and analysis for chromosome mutant micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis for animal model of chromosome rearrangementPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of mouse and cellular models of psychiatric disorders using a chromosome engineeringPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of embryonic stem cell-specific coacitvator UTF1 for tumorigenic property of ES cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 自閉症学2019

Author(s)

Total Pages

Publisher

Data Source

[Book] 今すぐ始めるゲノム編集2014

Author(s)

Total Pages

Publisher

Data Source

[Book] TALEN およびCRISPR/Cas9 を用いた染色体改変法 -簡便迅速かつ高効率な次世代染色体工学-, 実験医学別冊 今すぐ始めるゲノム編集2014

Author(s)

Publisher

Data Source

[Book] 自閉症のモデル動物, 自閉症の分子基盤, 分子精神医学, Vol.14, No.22014

Author(s)

Publisher

Data Source

[Book] 分子精神医学ー自閉症の分子基盤ー2014

Author(s)

Total Pages

Publisher

Data Source

[Book] A 15q11-q13 duplication mouse model of autism spectrum disorders. -IV MODEL SYSTEMS AND PATHWAYS IN AUTISM SPECTRUM DISORDERS- The Neuroscience of Autism Spectrum Disorders2013

Author(s)

Publisher

Data Source

[Book] The Neuroscience of Autism Spectrum Disorders2012

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Germ-cell-specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders2023

Author(s)

Journal Title

Data Source

[Journal Article] シングルセル，オルガノイド研究による細胞腫特異的自閉症リスク因子の同定2022

Author(s)

Nomura Jun 野村淳

野村淳ノムラジュン

NOMURA Jun 野村淳

[Book] TALEN およびCRISPR/Cas9 を用いた染色体改変法 -簡便迅速かつ高効率な次世代染色体工学-, 実験医学別冊今すぐ始めるゲノム編集2014