NAKAMURA Takahiro 中村隆弘

Researcher Number	70414018
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014: 金沢大学, がん進展制御研究所, 助教 2011 – 2012: 金沢大学, がん進展制御研究所, 助教 2009 – 2010: Kanazawa University, がん研究所, 助教 2007: Kanazawa University, Cancer Research Institute, 助教
Review Section/Research Field	Principal Investigator Pathological medical chemistry / General medical chemistry Except Principal Investigator Biological Sciences / General medical chemistry / Tumor biology / Functional biochemistry
Keywords	Principal Investigator HGF / Met / 組織再生 / シグナル伝達 / 細胞増殖因子 / 肝細胞増殖因子 Except Principal Investigator HGF / Met / 細胞増殖因子 / 転移 … More / 浸潤 / 組織再生 / チロシンキナーゼ / ノックアウトマウス / 悪性中皮種 / 腫瘍血管新生 / NK4 / 分子標的治療剤 / 受容体 / 再生医学 / シグナル伝達 / 肝再生 / 形態形成 / 薬剤耐性 / 人工アゴニスト / 環状ペプチド / がん細胞 / エピジェネティクス / PRC / MMP / 接触阻害 / チロシンフォスファターゼ / contact inhibition / tissue regeneration / knockout mouse / protein tyrosine phosnhatase / tyrosine kinase / growth factor Less

Mechanisms for malignant tumor progression based on acquisition of 3-D invasiveness and regulation of epithelial morphogenesis
- Principal Investigator
  
  MATSUMOTO Kunio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
Regulation of regeneration, disease and carcinogenesis throughthe ON-OFF conversion of the cMet/HGF receptor.Principal Investigator
- Principal Investigator
  
  NAKAMURA Takahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
Regulation of tissue regeneration, disease and oncogenesis through the natural isoform of the Met/HGF receptorPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Takahiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kanazawa University
Research on tissue regeneration regulated by Met/HGF receptor ON-OFF regulation
- Principal Investigator
  
  MATSUMOTO Kunio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kanazawa University
Metレセプター過剰発現に基づく悪性中皮腫の治療とNK4による制癌の至適化
- Principal Investigator
  
  MATSUMOTO Kunio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
  Osaka University
Regulation of tissue regeneration and homeostasis through ON-OFFcontrol of the Met/HGF receptor
- Principal Investigator
  
  MATSUMOTO Kunio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kanazawa University
  Osaka University

All 2015 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Patent

[Book] Hepatocyte growth factor. In “Reference Module in BiomedicalSciences”2015
- Author(s)
  Sakai K, Nakamura T, Kinoshita T, Matsumoto K.
- Publisher
  Elsevier Inc
- Data Source
  KAKENHI-PROJECT-24300329
[Book] Advances in Cancer Therapy2011
- Author(s)
  Sakai K, Nakamura T, Suzuki Y, and Matsumoto K
- Publisher
  Significance, Mechanisms, and Progress of Anticancer Drugs Targeting HGF-Met
- Data Source
  KAKENHI-PROJECT-23790327
[Book] In"Cancer Treatment"(Significance, mechanisms, and progress of anticancer drugs targeting HGF-Met)2011
- Author(s)
  Sakai K, Nakamura T, Suzuki Y, Matsumoto K
- Publisher
  InTech Open Access Publisher, in press
- Data Source
  KAKENHI-PROJECT-20390077
[Book] がん分子標的治療(HGF研究の進展と制癌剤開)2009
- Author(s)
  中村隆弘、櫻間晴子、中村敏一、松本邦夫
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-20390077
[Book] バイオ医薬開発技術とシーズ(山本重夫監修・(株))(新規がん分子標的薬-NK4(HGF アンタゴニスト/血管新生阻害分子)の開発-)2009
- Author(s)
  福田一弘、松本邦夫、中村敏一
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-20390077
[Book] がん分子標的治療 Vol.7 No.22009
- Author(s)
  中村隆弘
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21790312
[Book] “HGF"、「炎症・再生医学事典」2009
- Author(s)
  中村隆弘, 松本邦夫
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-20390077
[Book] がん分子標的治療Vol.7 No.22009
- Author(s)
  中村隆弘
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21790312
[Book] 炎症・再生医学事典(松島剛治・西脇徹編)(HGF)2009
- Author(s)
  中村隆弘、松本邦夫
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-20390077
[Book] Gene Therapy 20072007
- Author(s)
  Matsumoto K, Nakamura T
- Total Pages
  12
- Publisher
  Medical View Co.
- Data Source
  KAKENHI-PROJECT-18015031
[Book] Gene Therapy 20072007
- Author(s)
  Matsumoto K, Nakamura T
- Total Pages
  12
- Publisher
  Medical View Co.
- Data Source
  KAKENHI-PROJECT-18570127
[Book] 細胞増殖因子と再生医療2006
- Author(s)
  松本邦夫, 中村敏一
- Total Pages
  8
- Publisher
  メディカルレビュー社(東京)
- Data Source
  KAKENHI-PROJECT-18015031
[Book] 「細胞増殖因子と再生医療」2006
- Author(s)
  松本邦夫、中村敏一
- Total Pages
  8
- Publisher
  メディカルレビュー社(東京)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Book] 細胞増殖因子と再生医療2006
- Author(s)
  松本邦夫, 中村敏一
- Total Pages
  8
- Publisher
  メディカルレビュー社(東京)
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] a-Lipoic acid-induced inhibition of proliferation and Met phosphorylation in human non-small cell lung cancer cells.2013
- Author(s)
  Michikoshi H, Nakamura T, Sakai K, (他4名)
- Journal Title
  
  Cancer Lett
  
  Volume: 335(2) Pages: 472-478
- DOI
  10.1016/j.canlet.2013.03.008
- NAID
  120005254051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-24300329
[Journal Article] Met/HGF receptor activation isregulated by juxtamembrane Ser985phosphorylation in hepatocytes2013
- Author(s)
  Mizuho Nakayama
- Journal Title
  
  Cytokine.
  
  Volume: XXX Pages: 446-452
- DOI
  10.1016/j.cyto.2013.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-24300329
[Journal Article] Pharmacokinetic modeling of hepatocyte growth factor in experimental animals and humans.2013
- Author(s)
  Tomoko Sugiura et al.
- Journal Title
  
  J Pharm Sci
  
  Volume: 102(1) Pages: 237-249
- DOI
  10.1002/jps.23337
- NAID
  120005223453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590081, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390040, KAKENHI-PROJECT-24790150
[Journal Article] Oral administration of a novel long-acting prostacyclin agonist with thromboxane synthase inhibitory activity for pulmonary arterial hypertension.2013
- Author(s)
  Nakamura A, Nagaya N, Obata H, Sakai K, Sakai Y, Yoshikawa M, Hamada K, Matsumoto K, Kimura H.
- Journal Title
  
  Circulation J
  
  Volume: 77 Pages: 2127-2133
- NAID
  10031178685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300329
[Journal Article] mTOR inhibitors control the growth of EGFR mutant lung cancer even after acquiring resistance by HGF2013
- Author(s)
  Ishikawa D, Yano S, et al.
- Journal Title
  
  Plos One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0062104
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23591141, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24591156, KAKENHI-PROJECT-25860638, KAKENHI-PROJECT-25860640
[Journal Article] Interruption of the HGF paracrine loop by NK4, an HGF antagonist, reduces VEGF expression of CT26 cells.2013
- Author(s)
  Kubota T, Matsumura A, Taiyoh H, Izumiya Y, Fujiwara H, Okamoto K, Ichikawa D, Shiozaki A, Komatsu S, Nakanishi M, Kuriu Y, Murayama Y, Ikoma H, Ochiai T, Nakamura T, Matsumoto K, Nakamura T, Otsuji E.
- Journal Title
  
  Oncol Report
  
  Volume: 30 Pages: 567-572
- DOI
  10.3892/or.2013.2509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300329
[Journal Article] Met/HGF receptor activation is regulated by juxtamembrane Ser985 phosphorylation in hepatocytes2013
- Author(s)
  Nakayama M, Sakai K, Yamashita A, Nakamura T, Suzuki Y, and Matsumoto K
- Journal Title
  
  Cytokine
  
  Volume: (in press)
- URL
  http://www.sciencedirect.com/science/article/pii/S1043466613001543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790327
[Journal Article] The novel phosphoinositide 3-kinase-mammalian target of rapamycin inhibitor, BEZ235, circumvents erlotinib resistance of epidermal growth factor receptor mutant lung cancer cells triggered by hepatocyte growth factor2013
- Author(s)
  Sano T, Yano S, et al.
- Journal Title
  
  IntJ Cancer
  
  Volume: 133 Pages: 505-13
- DOI
  10.1002/ijc.28034
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-25860638
[Journal Article] HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells.2013
- Author(s)
  Matsumura A, Kubota T, Taiyoh H, Fujiwara H, Okamoto K, Ichikawa D, Shiozaki A, Komatsu S, Nakanishi M, Kuriu Y, Murayama Y, Ikoma H, Ochiai T, Kokuba Y, Nakamura T, Matsumoto K, and Otsuji E
- Journal Title
  
  Int J Oncol.
  
  Volume: Vol. 42: no.2 Pages: 535-542
- DOI
  10.3892/ijo.2012.1728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24591958
[Journal Article] α-Lipoic Acid-Induced Inhibition of Proliferation and Met Phosphorylation in Human Non-Small Cell Lung Cancer Cells2013
- Author(s)
  Michikoshi H, Nakamura T (contributed equally), Sakai K, Suzuki Y, Adachi E, Matsugo S, and Matsumoto K
- Journal Title
  
  α-Lipoic Acid-Induced Inhibition of Proliferation and Met Phosphorylation in Human Non-Small Cell Lung Cancer Cells
  
  Volume: (in press)
- NAID
  120005254051
- URL
  http://www.sciencedirect.com/science/article/pii/S030438351300236X
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790327
[Journal Article] Paracrine Receptor Activation by Microenvironment Triggers Bypass Survival Signals and ALK Inhibitor Resistance in EML4-ALK Lung Cancer Cells2012
- Author(s)
  Yamada, T.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 18 Pages: 3592-35602
- DOI
  10.1158/1078-0432.ccr-11-2972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689043, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24659403
[Journal Article] Combined therapy with mutantselective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer2012
- Author(s)
  Nakagawa T, Takeuchi S, Yamada T, Nanjo S, Ishikawa D, Sano T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Sekido Y, Uenaka T, and Yano S
- Journal Title
  
  Mol Cancer Ther
  
  Volume: Vol. 11: no.10 Pages: 2149-2157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790327
[Journal Article] Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR mutant lung cancer by decreasing client protein expression and angiogenesis2012
- Author(s)
  Koizumi H, Yamada T, Takeuchi S, Nakagawa T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, and Yano S
- Journal Title
  
  J Thoracic Oncol
  
  Volume: Vol. 7: no.7 Pages: 1078-1085
- DOI
  10.1097/jto.0b013e3182519a2c
- NAID
  40019570662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24659403, KAKENHI-PLANNED-22112010
[Journal Article] Hepatocyte Growth Factor Induces Resistance to Anti-Epidermal Growth Factor Receptor Antibody in Lung Cancer2012
- Author(s)
  Yamada T, Takeuchi S, Kita K, Bando H, Nakamura T, Matsumoto K, Yano S
- Journal Title
  
  J Thoracic Oncol
  
  Volume: 7 Pages: 272-280
- DOI
  10.1097/jto.0b013e3182398e69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209
[Journal Article] Suppression of acute hepatic injury by a synthetic prostacyclin agonist through hepatocyte growth factor expression2012
- Author(s)
  Qing Xu
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 302 Pages: 420-429
- DOI
  10.1152/ajpgi.00216.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-23790327
[Journal Article] Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer2012
- Author(s)
  Takeuchi S, Wang W, Li Q, Yamada T, Kita K, Donev IS, Nakamura T, Matsumoto K, Shimizu E, Nishioka Y, Sone S, Nakagawa T, Uenaka T, Yano
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 181 Pages: 1034-1043
- DOI
  10.1016/j.ajpath.2012.05.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390210, KAKENHI-PROJECT-24659403
[Journal Article] E7050, a Met kinase inhibitor, reverses three different mechanisms of hepatocyte growth factor-induced resistance to tyrosine kinase inhibitorsin EGFR mutant lung cancer cells2012
- Author(s)
  Wang W, Li Q, Takeuchi S, Yamada T, Koizumi H, Nakamura T, Matsumoto K, Mukaida N, Nishioka Y, Sone S, Uenaka T, Yano S
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 18 Pages: 1663-1671
- DOI
  10.1158/1078-0432.ccr-11-1171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390210
[Journal Article] Hepatocyte growth factor twenty years on : much more than a growth factor.2011
- Author(s)
  Sakai, K., Nakamura, T., Kinoshita, T., Nakamura, T., Matsumoto
- Journal Title
  
  Current Signal Transduction Therapy 6(2)
  
  Pages: 191-199
- NAID
  120003141437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] Recombinant human HGF, but not rat HGF; elicits glomerular injury and albuminuria in normal rats via an immune complex-dependent mechanism.2011
- Author(s)
  Mizuno S, Ikebuchi F, Fukuta K, Kato T, Matsumoto K, Adachi K, Nakamura T.
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 38 Pages: 192-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor twenty years on : much more than a growth factor.2011
- Author(s)
  Nakamura, T., Sakai, K., Nakamura, T., Matsumoto, K.
- Journal Title
  
  J.Gastroenterol.Hepatol. Suppl 1
  
  Pages: 188-202
- NAID
  120003141437
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] Cellular injury of cardiomyocytes during hepatocyte growth factor gene transfection with ultrasound-triggered bubble liposome destruction.2011
- Author(s)
  Komamura K, Tatsumi R, Tsujita-Kuroda Y, Onoe T, Matsumoto K, Nakamura T, Miyazaki J, Horio T, Sugimachi M.
- Journal Title
  
  J Drug Delivery
  
  Volume: 2011 Pages: 1-8
- NAID
  120004898438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor twenty years on : much more than a growth factor.2011
- Author(s)
  Nakamura T, Sakai K, Nakamura T, Matsumoto K.
- Journal Title
  
  J.Gastroenterol. Hepatol. 26
  
  Pages: 188-202
- NAID
  120003141437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor twenty years on: much more than a growth factor.2011
- Author(s)
  Nakamura T, Sakai K, Nakamura T, Matsumoto K.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 26 Pages: 188-202
- NAID
  120003141437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Recombinant human HGF, but not rat HGF, elicits glomerular injury and albuminuria in normal rats via an immune complex-dependent mechanism.2011
- Author(s)
  Mizuno S, Ikebuchi F, Fukuta K, Kato T, Matsumoto K, Adachi K, Nakamura T.
- Journal Title
  
  Clin Exp Pharmacol Physiol. 38
  
  Pages: 192-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor twenty years on: much more than a growth factor.2011
- Author(s)
  Nakamura.T
- Journal Title
  
  J.Gastroenterol.Hepatol.
  
  Volume: Suppl 1 Pages: 188-202
- NAID
  120003141437
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] NK4 Gene Expression Enhances 5-Fluorouracil -induced Apoptosis of Murine Colon Cancer Cells2011
- Author(s)
  Taiyoh H, Kubota T, Fujiwara H, Matsumura A, Murayama Y, Okamoto K, Ichikawa D, Ochiai T, Nakamura T, Matsumoto K, Nnakamura T, and Otsuji E
- Journal Title
  
  ANTICANCER RESEARCH
  
  Volume: Vol. 31 Pages: 2217-2224
- URL
  http://ar.iiarjournals.org/content/31/6/2217.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790327
[Journal Article] HGF-Antagonists : Structure, Activities, and Anti-cancer Approach.2011
- Author(s)
  Sakai K, Nakamura T, Kinoshita T, Nakamura T, Matsumoto K.
- Journal Title
  
  Current Signal Transduction Therapy 6
  
  Pages: 191-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] HGF-antagonists : structure, activities, and anti-cancer approach.2011
- Author(s)
  Sakai K, Nakamura T, Kinoshita T, Nakamura T, Matsumoto, K.
- Journal Title
  
  Current Signal Transduction Therapy
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] 3-D collagen-dependent cell surface expression of MT1-MMP and MMP-2 activation regardless of integrin b1 function and matrix stiffness2011
- Author(s)
  Sakai K, Nakamura T, Suzuki Y, ImizuT, and Matsumoto K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 412 Pages: 98-103
- DOI
  10.1016/j.bbrc.2011.07.050
- NAID
  120003308573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-23790327
[Journal Article] Cellular injury of cardiomyocytes during hepatocyte growth factor gene transfection with ultrasound-triggered bubble liposome destruction.2011
- Author(s)
  Komamura, K., Tatsumi, R., Tsujita-Kuroda, Y., Onoe, T., Matsumoto, K., Nakamura, T., Miyazaki, J., Horio, T., Sugimachi, M.
- Journal Title
  
  J.Drug Delivery 2011
  
  Pages: 1-8
- NAID
  120004898438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] p27 Nuclear localization and growth arrest caused by perlecan knockdown in human endothelial cells.2010
- Author(s)
  Sakai K Oka K, Matsumoto K, Nakamura T.
- Journal Title
  
  Biochcm.Biophys.Res.Commun.
  
  Volume: 3 Pages: 403-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Anti-cancer approach with NK4 : Bivalent action and mechanisms.2010
- Author(s)
  Nakamura T, Sakai K, Nakamura T, Matsumoto K.
- Journal Title
  
  Anti-Cancer Agent Med. Chem. 10(1)
  
  Pages: 36-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Inhibition of Met/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma.2010
- Author(s)
  Suzuki, Y., Sakai, K., Ueki, J., Xu, Q., Nakamura, T., Shimada, H., Nakamura, T., Matsumoto, K.
- Journal Title
  
  Int.J.Cancer 127
  
  Pages: 1948-1957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] Anti-cancer approach with NK4 : Bivalent action and mechanisms2010
- Author(s)
  Nakamura T, Matsumoto K, et al.
- Journal Title
  
  Anti-cancer Agent Med. Chem. 10
  
  Pages: 36-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] p27 Nuclear localization and growth arrest caused by perlecan knockdown in human endothelial cells.2010
- Author(s)
  Sakai K, Oka K, Matsumoto K, Nakamura T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 392
  
  Pages: 403-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Anti-cancer approach with NK4 : Bivalent action and mechanisms.2010
- Author(s)
  Nakamura T, Sakai K, Nakamura T,Matsumoto K.
- Journal Title
  
  Anti-cancer Agent Med.Chem.
  
  Volume: 10 Pages: 36-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Inhibition of Met/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma.2010
- Author(s)
  Suzuki Y, Sakai K, Ueki J, Xu Q, Nakamura T, Shimada H, Nakamura T, Matsumoto K.
- Journal Title
  
  Int.J.Cancer 127
  
  Pages: 1948-1957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Inhibition of Met/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma.2010
- Author(s)
  Suzuki Y, Sakai K, Ueki J, Xu Q, Nakamura T, Shimada H, Nakamura T, Matsumoto K.
- Journal Title
  
  Int.J.Cancer
  
  Volume: 127 Pages: 1948-1957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Anti-cancer approach with NK4 : Bivalent action and mechanisms.2010
- Author(s)
  Nakamura.T
- Journal Title
  
  Anti-cancer Agent Med.Chem. 10
  
  Pages: 36-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] K.Anti-cancer approach with NK4 : Bivalent action and mechanisms.2010
- Author(s)
  akamura, T., Sakai, K., Nakamura, T., Matsumoto
- Journal Title
  
  Anti-Cancer Agent Med.Chem. 10(1)
  
  Pages: 36-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] HGF研究の進展と制癌剤開発2009
- Author(s)
  中村隆弘, 松本邦夫
- Journal Title
  
  がん分子標的治療(メディカルレビュー社) 7
  
  Pages: 92-101
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Characterization of the enhancing effect of protamine on the proliferative activity of hepatocyte growth factor in rat hepatocytes.2009
- Author(s)
  Liu KX, Kato Y, Matsumoto K, Nakamura T, Kaku T, Sugiyama Y.
- Journal Title
  
  Pharm. Res. 26
  
  Pages: 1012-1021
- NAID
  120001063570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Systemic NK4 gene therapy inhibits tumor growth and metastasis of melanoma and lung carcinoma in syngeneic mouse tumor models.2009
- Author(s)
  Kishi Y, Kuba K, Nakamura T, Wen J, Suzuki Y, Mizuno S, Nukiwa T, Matsumoto K, Nakamura T.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1351-1358
- NAID
  10027192650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] T.Systemic NK4 gene therapy inhibits tumor growth and metastasis of melanoma and lung carcinoma in syngeneic mouse tumor models.2009
- Author(s)
  Kishi, Y., Kuba, K., Nakamura, T., Wen, J., Suzuki, Y., Mizuno, S, Nukiwa, T., Matsumoto, K, Nakamura
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 1351-1358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] T.Angioinhibitory Action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.2009
- Author(s)
  Sakai, K., Nakamura, T., Matsumoto, K., Nakamura
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 22491-22499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] Different reactivities of enzyme-linked immunosorbent assays for hepatocyte growth factor.2009
- Author(s)
  Fukuta K, Adachi E, Matsumoto K, Nakamura, T.
- Journal Title
  
  Clinica Chimica Acta 402
  
  Pages: 42-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] T.Diseasedependent reciprocal phosphorylation of serine and tyrosine residues of c-Met/HGF receptor contributes disease retardation of a transgenic mouse model of ALS.2009
- Author(s)
  Kadoyama, K., Funakoshi, H., Ohya- Shimada, W., Nakamura, T., Matsumoto, K., Matsuyama, S., Nakamura
- Journal Title
  
  Neurosci.Res. 65
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790312
[Journal Article] Gene transfer of NK4, an angiogenesis inhibitor, induces CT26 tumor regression via tumor-specific T-lymphocyte activation.2009
- Author(s)
  Kubota T, Taiyoh H, Matsumura A, Murayama Y, Ichikawa D, Okamoto O, Fujiwara H, Ikoma H, Nakanishi N, Kikuchi S, Ochiai T, Sakakura C, Kokuba Y, Suzuki Y,Matsumoto K, Nakamura T, Otsuji E.
- Journal Title
  
  Int.J.Cancer. 125
  
  Pages: 2879-2886
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor prevents multiple organ injuries in endotoxemic mice through a heme oxygenase-1-dependent mechanism.2009
- Author(s)
  Kamimoto M, Mizuno S, Matsumoto K, Nakamura T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 380
  
  Pages: 333-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article]2009
- Author(s)
  中村隆弘, 松本邦夫
- Journal Title
  
  炎症・再生医学事典(朝倉書店)
  
  Pages: 518-521
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] NK4, an HGF ntagonist, prevents hematogenous pulmonary metastasis by inhibiting adhesion of CT26 cells to endothelial cells.2009
- Author(s)
  Kubota T, Fujiwara H, Matsumura A, Taiyoh H, Ichikawa I, Okamoto K, Matsumoto M, Nakamura T, Otsuji E.
- Journal Title
  
  Clin.Exp.Metastasis 26
  
  Pages: 447-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice.2009
- Author(s)
  Kanai M, Funakoshi H, Takahashi H, Hayakawa T, Mizuno S, Matsumoto K, Nakamura T.
- Journal Title
  
  Mol.Brain 2
  
  Pages: 8-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article]2009
- Author(s)
  中村隆弘, 極本邦夫, 他
- Journal Title
  
  がん分子標的治療Vol. 7 No. 2(メディカルレビュー社)
  
  Pages: 92-101
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Angioinhibitory Action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.2009
- Author(s)
  Sakai K, Nakamura T, Matsumoto K, Nakamura T.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 22491-22499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Disease-dependent reciprocal phosphorylation of serine and tyrosine residues of c-Met/HGF receptor contributes disease retardation of a transgenic mouse model of ALS.2009
- Author(s)
  Kadoyama K, Funakoshi H, Ohya-Shimada W, Nakamura T, Matsumoto K, Matsuyama S, Nakamura T.
- Journal Title
  
  Neurosci.Res. 65
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Radiation enhances adenoviral gene therapy in pancreatic cancer via activation of cytomegalovirus promoter and increased adenovirus uptake.2008
- Author(s)
  Egami T, Ohuchida K, Mizumoto K, Onimaru M, Toma H, Nishio S, Nagai E, Matsumoto K, Nakamura T, Tanaka M.
- Journal Title
  
  Clin.CancerRes. 14
  
  Pages: 1859-1867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor as a renotrophic and anti-fibrotic regulator in chronic renal disease.2008
- Author(s)
  Mizuno S, Matsumoto K, Nakamura T.
- Journal Title
  
  Front.Biosci. 13
  
  Pages: 7072-7086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Regulation of cell migration and cytokine production by HGF-like protein(HLP)/macrophage stimulating protein(MSP) in primary microglia2008
- Author(s)
  Suzuki, Y., Funakoshi, H., Machide, M., Matsumoto, K., Nakamura, T
- Journal Title
  
  Biomed. Res 29
  
  Pages: 77-84
- NAID
  130004724052
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] The functions and possible significance of Kremen as the gatekeeper of Wnt signaling in development and pathology.2008
- Author(s)
  Nakamura T., et. al.
- Journal Title
  
  J. Cell. Mol. Med. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015031
[Journal Article] The functions and possible significance of Kremen as the gatekeeper of Wnt signaling in development and pathology2008
- Author(s)
  Nakamura, T., Nakamura, T., Matsumoto, K
- Journal Title
  
  J. Cell. Mol. Med 12
  
  Pages: 391-408
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] The functions and possible significance of Kremen as the gatekeeper of Wnt signaling in development and palhology.2008
- Author(s)
  Nakamura T, Malsumolo K, et al.
- Journal Title
  
  J. Cell. Mol. Med. 12
  
  Pages: 391-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor improves synaptic localization of the NMDA receptor and intracellular signaling after excitotoxic injury in cultured hippocampal neurons.2008
- Author(s)
  Akita H, Takagi N, Ishihara N, Takagi K, Murotomi K, Funakoshi H, Matsumoto K, Nakamura T, Takeo S.
- Journal Title
  
  Exp Neurol. 210(1)
  
  Pages: 83-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] NK4 gene therapy targeting HGF-Met and angiogenesis2008
- Author(s)
  Matsumoto, K., Nakamura, T
- Journal Title
  
  Front Biosci 13
  
  Pages: 1943-1951
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Hepatocyte Growth Factor and Met in Tumor Biology and Therapeutic Approach with NK4.2008
- Author(s)
  Matsumoto K, Nakamura T, Sakai K, Nakamura T.
- Journal Title
  
  Proteomics 8
  
  Pages: 3360-3370
- NAID
  120001130499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] NK4 gene therapy targeting HGF-Met and angiogenesis.2008
- Author(s)
  Matsumoto K, Nakamura T.
- Journal Title
  
  Front Biosci. 13
  
  Pages: 1943-1951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Growth factors temporally associate with airway responsiveness and inflammation in allergen-exposed mice2008
- Author(s)
  Ito, W., Tanimoto, M., Ono, K., Mizuno, S., Yoshida, A., Koga, H., Fuchimoto, Y., Kondo, N., Tanimoto, Y., Kiura, K., Matsumoto, K., Kataoka, M., Nakamura, T., Gelfand, E., Kanehiro, A
- Journal Title
  
  Int. Arch. Allergy Immunol 145
  
  Pages: 324-339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Hepatocyte growth factor as a renotrophic and anti-fibrotic regulator in chronic renal disease2008
- Author(s)
  Mizuno, S., Matsumoto, K., Nakamura, T
- Journal Title
  
  Front. Biosci 13
  
  Pages: 7072-7086
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Growth factors temporally associate with airway responsiveness and inflammation in allergen-exposed mice.2008
- Author(s)
  Ito W, Tanimoto M, Ono K, Mizuno S, Yoshida A, Koga H, Fuchimoto Y, Kondo N, Tanimoto Y, Kiura K, Matsumoto K, Kataoka M, Nakamura T, Gelfand E, Kanehiro A.
- Journal Title
  
  Int.Arch.Allergy Immunol. 145
  
  Pages: 324-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Reduction of fibrosis in a rat model of non-alcoholic steatohepatitis cirrhosis by human HGF gene transfection using electroporation.2008
- Author(s)
  Kiyama S, Yamada T, Iwata H, Sekino T, Matsuo H, Yoshida N, Miyahara T, Umeda Y, Matsuno Y, Kimura M, Matsumoto K, Nakamura T, Takemura H.
- Journal Title
  
  J.Gastroenterol.Hepatol. 23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Hepatocyte growth factor improves synaptic localization of the NMDA receptor and intracellular signaling after excitotoxic injury in cultured hippocampal neurons2008
- Author(s)
  Akita, H., Takagi, N., Ishihara, N., Takagi, K., Murotomi, K., Funakoshi, H., Matsumoto, K., Nakamura, T., Takeo, S
- Journal Title
  
  Exp Neurol 210(1)
  
  Pages: 83-94
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Generation of engineered recombinant hepatocyte growth factor cleaved and activated by Genenase I.2008
- Author(s)
  Hayata D, Fukuta K, Matsumoto K, Adachi E, Hanada K, Adachi K, Nakamura T.
- Journal Title
  
  J Biotechnol. 133
  
  Pages: 478-485
- NAID
  120000811714
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] The functions and possible significance of Kremen as the gatekeeper of Wnt signaling in development and pathology.2008
- Author(s)
  Nakamura T., et. al.
- Journal Title
  
  J. Cell. Mol. Med. 12
  
  Pages: 391-408
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with EGF Receptor activating mutations.2008
- Author(s)
  Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakamura T, Ogino H, Kakiuchi S, Hanibuchi M, Nishioka Y, Uehara H, Mitsudomi T, Yatabe Y, Nakamura T, Sone S.
- Journal Title
  
  Cancer Res. 68
  
  Pages: 9479-9487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] The functions and possible significance of Kremen as the gatekeeper of Wnt signaling in development and pathology.2008
- Author(s)
  Nakamura T, Nakamura T, Matsumoto K.
- Journal Title
  
  J.Cell.Mol.Med. 12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] Generation of engineered recombinant hepatocyte growth factor cleaved and activated by Genenase I2008
- Author(s)
  Hayata, D., Fukuta, K., Matsumoto, K., Adachi, E., Hanada, K., Adachi, K., Nakamura, T
- Journal Title
  
  J Biotechnol 133
  
  Pages: 478-485
- NAID
  120000811714
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] The functions and possible significance of Kremen as the gatekeeper of Wnt signaling in development and pathology2008
- Author(s)
  Nakamura T., et. al.
- Journal Title
  
  J.Cell.Mol.Med. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Regulation of cell migration and cytokine production by HGF-like protein (HLP)/macrophage stimulating protein (MSP) in primary microglia.2008
- Author(s)
  Suzuki Y, Funakoshi H, Machide M, Matsumoto K, Nakamura T.
- Journal Title
  
  Biomed.Res. 29
  
  Pages: 77-84
- NAID
  130004724052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390077
[Journal Article] NK4 gene therapy targeting HGF-Met and angiogenesis2007
- Author(s)
  Matsumoto, K., Nakamura
- Journal Title
  
  In "Gene Therapy 2007" (eds, Ochiai, T., Shimada, H., Tagawa, M.)
  
  Pages: 22-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Hepatocyte growth factor promotes the number of PSD-95 clusters in young hippocampal neurons2007
- Author(s)
  Nakano, M., Takagi, N., Takagi, K., Funakoshi, H., Matsumoto, K., Nakamura, T., Takeo, S
- Journal Title
  
  Exp. Neurol 207(2)
  
  Pages: 195-202
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Inhibition of colon cancer growth and metastasis by NK4 gene repetitive delivery in mice2007
- Author(s)
  Wen, J., Matsumoto, K., Taniura, N., Tomioka, D., Nakamura, T
- Journal Title
  
  Biochem. Biophys. Res. Commun 358
  
  Pages: 117-123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Hepatocyte growth factor prevents pulmonary ischemia-reperfusion injury in mice2007
- Author(s)
  Makiuchi, A., Yamaura, K., Mizuno, S., Matsumoto, K., Nakamura, T., Amano, J., Ito, K
- Journal Title
  
  J. Heart Lung Transplant
  
  Pages: 935-943
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] A genomic analysis of adult T-cell leukemia2007
- Author(s)
  Choi, Y.L., Tsukasaki, K., O'neill, M.C., Yamada, Y., Onimaru, Y., Matsumoto, K., Ohashi, J., Yamashita, Y., Tsutsumi, S., Kaneda, R., Takada, S., Aburatani, H., Kamihira, S., Nakamura, T., Tomonaga, M., Mano, H
- Journal Title
  
  Oncogene 26
  
  Pages: 1245-1255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] A genomic analysis of adult T-cell leukemia2007
- Author(s)
  Choi, Y. L., Tsukasaki, K., O'neill, M., C., Yamada, Y., Onimaru, Y., Matsumoto, K., Ohashi, J., Yamashita, Y., Tsutsumi, S., Kaneda, R., Takada, S., Aburatani, H., Kamihira, S., Nakamura, T., Tomonaga, M., Mano, H
- Journal Title
  
  Oncogene 26
  
  Pages: 1245-1255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] NK4, an antagonist of hepatocyte growth factor (HGF), inhibits growth of multiple myeloma cells in vivo ; molecular targeting of angiogenic growth factor2007
- Author(s)
  Du, W., Hattori, Y., Yamada, T., Matsumoto, K., Nakamura, T., Sagawa, M., Otsuki, T., Niikura, T., Nukiwa, T., Ikeda, Y
- Journal Title
  
  Blood 109
  
  Pages: 3042-3049
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Stimulation of Hepatocyte Growth Factor Production by Heparin-derived Oligosaccharides2007
- Author(s)
  Sakiyama, R., Fukuta, K., Matsumoto, K., Furukawa, M., Takahashi, Y., Nakamura, T
- Journal Title
  
  J. Biochem 141
  
  Pages: 653-660
- NAID
  10020099195
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells2007
- Author(s)
  Kanehira, M., Xin, H., Hoshino, K., Maemondo, M., Mizuguchi, H., Hayakawa, T., Matsumoto, K., Nakamura, T., Nukiwa, T., Saijo, Y
- Journal Title
  
  Cancer Gene Ther 14
  
  Pages: 894-903
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Liver targeting of plasmid DNA with a cationized pullulan for tumor suppression2006
- Author(s)
  Jo, J., Yamamoto, M., Matsumoto, K., Nakamura, T., Tabata, Y
- Journal Title
  
  J. Nanosci. Nanotechnol 6
  
  Pages: 2853-2859
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions2006
- Author(s)
  Matsumoto, K., Nakamura, T
- Journal Title
  
  Int. J. Cancer 119
  
  Pages: 477-483
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] The protective effect of hepatocyte growth factor against cell death in the hippocampus after transient forebrain ischemia is related to the improvement of apurinic/apyrimidinic endonuclease/redox factor-1 level and inhibition of NADPH oxidase activity2006
- Author(s)
  Niimura, M., Takagi, N., Takagi, K., Mizutani, R., Tanonaka, K., Funakoshi, H., Matsumoto, K., Nakamura, T., Takeo, S
- Journal Title
  
  Neurosci. Lett. 407
  
  Pages: 136-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Peritumoral injection of adenovirus vector expressing NK4 combined with gemcitabine treatment suppresses growth and metastasis of human pancreatic cancer cells implanted orthotopically in nude mice and prolongs survival2006
- Author(s)
  Ogura, Y., Mizumoto, K., Nagai, E., Murakami, M., Inadome, N., Saimura, M., Matsumoto, K., Nakamura, T., Maemondo, M., Nukiwa, T., Tanaka, M
- Journal Title
  
  Cancer Gene Ther 13
  
  Pages: 520-529
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Intraventricular administration of hepatocyte growth factor treats mouse communicating hydrocephalus induced by transforming growth factor-β12006
- Author(s)
  Tada, T., Zhan, H., Tanaka, Y., Hongo, K., Matsumoto, K., Nakamura, T
- Journal Title
  
  Neurobiol. Disease 21
  
  Pages: 576-586
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Blockage of HGF/c-Met system by gene therapy (adenovirus-mediated NK4 gene) suppresses hepatocellular carcinoma in mice2006
- Author(s)
  Son, G., Hirano, T., Seki, E., Iimuro, Y., Nukiwa, T., Matsumoto, K., Nakamura, T., Fujimoto, J
- Journal Title
  
  J. Hepatol 45
  
  Pages: 688-695
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Model of vasculogenesis from embryonic stem cells for vascular research and regenerative medicine2006
- Author(s)
  Nakagami, H., Nakagawa, N., Takeya, Y., Kashiwagi, K., Ishida, C., Hayashi, S., Aoki, M., Matsumoto, K., Nakamura, T., Ogihara, T., Morishita, R
- Journal Title
  
  Hypertension 48
  
  Pages: 112-119
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Enhanced suppression of tumor growth using a combination of NK4 plasmid DNA-PEG engrafted cationized dextran complex and ultrasound irradiation2006
- Author(s)
  Hosseinkhani, H., Kushibiki, T., Matsumoto, K., Nakamura, T., Tabata, Y
- Journal Title
  
  Cancer Gene Therapy 13
  
  Pages: 479-489
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Preclinical study of a "tailor-made" combination of NK4-expressing gene therapy and gefitinib (ZD1839, Iressatrade mark) for disseminated peritoneal scirrhous gastric cancer2006
- Author(s)
  Narniki, Y., Namiki, T., Yoshida, H., Date, M., Yashiro, M., Matsumoto, K., Nakamura, T., Yanagihara, K., Tada, N., Satoi, J., Fujise, K
- Journal Title
  
  Int. J. Cancer 118
  
  Pages: 1545-1555
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Angiogenic and antifibrotic actions of hepatocyte growth factor improve cardiac dysfunction in porcine ischemic cardiomyopathy2006
- Author(s)
  Azuma, J., Taniyama, Y., Takeya, Y., Iekushi, K., Aoki, M., Dosaka, N., Matsumoto, K., Nakamura, T., Ogihara, T., Morishita, R
- Journal Title
  
  Gene Therapy 13
  
  Pages: 1206-1213
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Hepatocyte growth factor attenuates cerebral ischemia-induced increase in permeability of the blood-brain barrier and decreases in expression of tight junctional proteins in cerebral vessels2006
- Author(s)
  Date, I., Takagi, N., Takagi, K., Tanonaka, K., Funakoshi, H., Matsumoto, K., Nakamura, T., akeo, S
- Journal Title
  
  Neurosci. Lett. 407
  
  Pages: 141-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Prevention of apoptosis-inducing factor translocation is a possible mechanism for protective effects of hepatocyte growth factor against neuronal cell death in the hippocampus after transient forebrain ischemia2006
- Author(s)
  Niimura, M., Takagi, N., Takagi, K., Mizutani, R., Ishihara, N., Matsumoto, K., Funakoshi, H., Nakamura, T., Takeo, S
- Journal Title
  
  J. Cereb. Blood Flow Metab 26
  
  Pages: 1354-1365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Different activity regulation and subcellular localization of LIMKI1 and LIMK2 during cell cycle transition2006
- Author(s)
  Sumi, T., Hashigasako, A., Matsumoto, K., Nakamura, T
- Journal Title
  
  Exp. Cell Res 312
  
  Pages: 1021-2030
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Involvement of hepatocyte growth factor in the development of bone metastasis of a mouse mammary cancer cell line, BALB/c-MC2006
- Author(s)
  Ono, K., Kamiya, S., Akatsu, T., Nakamura, C., Li, M., Amizuka, N., Matsumoto, K., Nakamura, T., Kugai, N., Wada, S
- Journal Title
  
  Bone 39
  
  Pages: 27-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Contact inhibition of hepatocyte growth regulated by functional association of the c-Met/HGF receptor and LAR protein tyrosine phosphatase2006
- Author(s)
  Machide, M., Hashigasako, A., Matsumoto, K., Nakamura, T
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 8765-8772
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Hepatocyte Growth Factor and Met in Tumor Biology and Therapeutic Approach with NK4
- Author(s)
  Matsumoto, K., Nakamura, T., Sakai, K., Nakamura, T
- Journal Title
  
  Proteomics (in press)
- NAID
  120001130499
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Journal Article] Reduction of fibrosis in a rat model of non-alcoholic steatohepatitis cirrhosis by human HGF gene transfection using electroporation
- Author(s)
  Kiyama, S., Yamada, T., Iwata, H., Sekino, T., Matsuo, H., Yoshida, N., Miyahara, T., Umeda, Y., Matsuno, Y., Kimura, M., Matsumoto, K., Nakamura, T., Takemura, H
- Journal Title
  
  J. Gastroenterol. Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18570127
[Patent] 喘息治療剤2007
- Inventor(s)
  金廣有彦、中村敏一、谷本光音、伊藤亘、松本邦夫
- Industrial Property Rights Holder
  中村敏一・クリングルファーマ
- Acquisition Date
  2007-10-31
- Overseas
- Data Source
  KAKENHI-PROJECT-18015031
[Patent] 喘息治療剤2007
- Inventor(s)
  金廣有彦、中村敏一、谷本光音、伊藤亘、松本邦夫
- Industrial Property Rights Holder
  中村敏一・クリングルファーマ
- Acquisition Date
  2007-10-31
- Overseas
- Data Source
  KAKENHI-PROJECT-18570127
[Presentation] 肺がん細胞を用いたWnt/b-cateninシグナル抑制におけるKremenの機能解析.2012
- Author(s)
  中村隆弘
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] 肺がん細胞を用いたWnt/betacateninシグナル抑制におけるKremen1の機能解析2012
- Author(s)
  中村隆弘
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23790327
[Presentation] Functional Analyses of the Kremen in Lung Cancer Cells through Wnt/β-catenin Signaling Pathway2011
- Author(s)
  中村隆弘
- Organizer
  日本生化学会第84回大会
- Place of Presentation
  京都国際会議場（京都府）
- Data Source
  KAKENHI-PROJECT-23790327
[Presentation] Functional Analyses of the Kremen in Lung Cancer Cells through Wnt/β-catenin Signaling Pathway2011
- Author(s)
  中村隆弘
- Organizer
  日本分子生物学会北陸支部第11回シンホシウム
- Place of Presentation
  石川県立音楽堂(石川県)
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-23790327
[Presentation] Functional Analyses of the Kremen in Lung Cancer Cells through Wnt/β-catenin Signaling Pathway2011
- Author(s)
  中村隆弘
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23790327
[Presentation] Functional analysis of the Kremen in Lewis lung carcinoma cells throughWnt/β-catenin cionalino nathwav2010
- Author(s)
  Quing Xu, Masataka Fujikawa, Takahiro Nakamura, Kunio Matsumoto.
- Organizer
  第33回日本分子生物学会年会・日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] Pcrlecanによるp27の発現ならびに細胞内細胞内局在の制御を介した血管内皮細胞の増殖制御2010
- Author(s)
  酒井克也、岡清正、中村隆弘、松本邦夫、中村敏一
- Organizer
  第33回日本分子生物学会年会・日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] 肝細胞におけるMet/HGF受容体Ser985リン酸化と受容体活性化の制御2010
- Author(s)
  中山瑞穂、山下敦子、中村隆弘、徐慶、中村敏一、松本邦夫
- Organizer
  第33回同本分子生物学会年会・日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] Functional analysis of the Kremen in Lewis lung carcinoma cells throughWnt/b-catenin signaling pathway.2010
- Author(s)
  Xu Q, Fujikawa M, Nakamura T, Matsumoto K
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] 肝細胞におけるMet/HGF受容体Ser985リン酸化と受容体活性化の制御2010
- Author(s)
  中山瑞穂、中村敏一, (他4名)
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20390077
[Presentation] Kremenによる肺がん細胞におけるWnt/β-cateninシグナルの調節.
- Author(s)
  中村隆弘、酒井克也、足立恵理、松本邦夫
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24300329
[Presentation] 肺がん細胞を用いたWnt/beta-cateninシグナル抑制におけるKremen1の機能解析
- Author(s)
  中村隆弘
- Organizer
  日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-23790327
[Presentation] リポ酸によるヒト肺がん細胞増殖抑制機構の解析.
- Author(s)
  松郷誠一、道越洸充、中村隆弘、酒井克也、松本邦夫
- Organizer
  第8回α―リポ酸研究会
- Place of Presentation
  富山国際会議場（富山県）
- Data Source
  KAKENHI-PROJECT-24300329

1. MATSUMOTO Kunio (90201780)

# of Collaborated Projects: 4 results

# of Collaborated Products: 95 results
2. SAKAI Katsuya (10523318)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
3. YAMADA Tadaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
4. TAKEUCHI Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
5. SUGIURA Tomoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. WANG Wei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. YOSHIZAWA Hirohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 矢野聖二

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
9. 曽根三郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 西岡安彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 各務博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 藤原斉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 大辻英吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAMURA Takahiro 中村 隆弘

Research Projects

Research Products

Co-Researchers

Mechanisms for malignant tumor progression based on acquisition of 3-D invasiveness and regulation of epithelial morphogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of regeneration, disease and carcinogenesis throughthe ON-OFF conversion of the cMet/HGF receptor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of tissue regeneration, disease and oncogenesis through the natural isoform of the Met/HGF receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on tissue regeneration regulated by Met/HGF receptor ON-OFF regulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metレセプター過剰発現に基づく悪性中皮腫の治療とNK4による制癌の至適化

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of tissue regeneration and homeostasis through ON-OFFcontrol of the Met/HGF receptor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Hepatocyte growth factor. In “Reference Module in BiomedicalSciences”2015

Author(s)

Publisher

Data Source

[Book] Advances in Cancer Therapy2011

Author(s)

Publisher

Data Source

[Book] In"Cancer Treatment"(Significance, mechanisms, and progress of anticancer drugs targeting HGF-Met)2011

Author(s)

Publisher

Data Source

[Book] がん分子標的治療(HGF研究の進展と制癌剤開)2009

Author(s)

Publisher

Data Source

[Book] バイオ医薬開発技術とシーズ(山本重夫監修・(株))(新規がん分子標的薬-NK4(HGF アンタゴニスト/血管新生阻害分子)の開発-)2009

Author(s)

Publisher

Data Source

[Book] がん分子標的治療 Vol.7 No.22009

Author(s)

Publisher

Data Source

[Book] “HGF"、「炎症・再生医学事典」2009

Author(s)

Publisher

Data Source

[Book] がん分子標的治療Vol.7 No.22009

Author(s)

Publisher

Data Source

[Book] 炎症・再生医学事典(松島剛治・西脇徹編)(HGF)2009

Author(s)

Publisher

Data Source

[Book] Gene Therapy 20072007

Author(s)

Total Pages

Publisher

NAKAMURA Takahiro 中村隆弘